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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

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Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for ILDR2

check button Gene summary
Gene informationGene symbol

ILDR2

Gene ID

387597

Gene nameimmunoglobulin like domain containing receptor 2
SynonymsC1orf32|dJ782G3.1
Cytomap

1q24.1

Type of geneprotein-coding
Descriptionimmunoglobulin-like domain-containing receptor 2
Modification date20200313
UniProtAcc

Q71H61,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for ILDR2

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_41288(166896702, -), ADediting_41289(166896703, -), ADediting_41290(166896704, -), ADediting_41291(166896747, -), ADediting_41292(166896760, -), ADediting_41293(166896773, -), ADediting_41294(166896774, -), ADediting_41295(166896800, -), ADediting_41296(166896814, -), ADediting_41297(166896817, -), ADediting_41298(166896834, -), ADediting_41299(166896853, -), ADediting_41300(166896907, -), ADediting_41301(166896908, -), ADediting_41302(166896914, -), ADediting_41303(166898803, -), ADediting_41304(166898815, -), ADediting_41305(166898816, -), ADediting_41306(166898837, -), ADediting_41307(166898838, -), ADediting_41308(166898841, -), ADediting_41309(166898855, -), ADediting_41310(166898892, -), ADediting_41311(166898893, -), ADediting_41312(166898938, -), ADediting_41313(166898965, -), ADediting_41314(166898977, -), ADediting_41315(166898984, -), ADediting_41316(166899026, -), ADediting_41317(166899027, -), ADediting_41318(166899028, -), ADediting_41319(166899054, -), ADediting_41320(166899190, -), ADediting_41321(166899208, -), ADediting_41322(166899227, -), ADediting_41323(166899230, -), ADediting_41324(166899245, -), ADediting_41325(166899271, -), ADediting_41326(166899284, -), ADediting_41327(166899293, -), ADediting_41328(166899306, -), ADediting_41329(166899310, -), ADediting_41330(166899330, -), ADediting_41331(166899349, -), ADediting_41332(166901989, -), ADediting_41333(166901998, -), ADediting_41334(166901999, -), ADediting_41335(166902025, -), ADediting_41336(166902038, -), ADediting_41337(166902097, -), ADediting_41338(166902110, -), ADediting_41339(166902132, -), ADediting_41340(166902133, -), ADediting_41341(166910982, -), ADediting_41342(166911000, -), ADediting_41343(166911013, -), ADediting_41344(166911018, -), ADediting_41345(166911022, -), ADediting_41346(166911028, -), ADediting_41347(166911035, -), ADediting_41348(166911036, -), ADediting_41349(166911041, -), ADediting_41350(166913860, -), ADediting_41351(166913887, -), ADediting_41352(166913895, -), ADediting_41353(166913899, -), ADediting_41354(166913912, -), ADediting_41355(166913913, -), ADediting_41356(166913914, -), ADediting_41357(166913949, -), ADediting_41358(166913951, -), ADediting_41359(166913985, -), ADediting_41360(166913993, -), ADediting_41361(166914029, -), ADediting_41362(166914032, -), ADediting_41363(166914033, -), ADediting_41364(166914038, -), ADediting_41365(166914062, -), ADediting_41366(166965711, -), ADediting_41367(166971661, -), ADediting_1516223(166898936, -), ADediting_1516224(166899135, -), ADediting_1516225(166902092, -), ADediting_1596973(166926759, -),

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RNA editing positional annotations for ILDR2 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_41288chr1_166896702_-intergenic
ADediting_41289chr1_166896703_-intergenic
ADediting_41290chr1_166896704_-intergenic
ADediting_41291chr1_166896747_-intergenic
ADediting_41292chr1_166896760_-intergenic
ADediting_41293chr1_166896773_-intergenic
ADediting_41294chr1_166896774_-intergenic
ADediting_41295chr1_166896800_-intergenic
ADediting_41296chr1_166896814_-intergenic
ADediting_41297chr1_166896817_-intergenic
ADediting_41298chr1_166896834_-intergenic
ADediting_41299chr1_166896853_-intergenic
ADediting_41300chr1_166896907_-intergenic
ADediting_41301chr1_166896908_-intergenic
ADediting_41302chr1_166896914_-intergenic
ADediting_41303chr1_166898803_-intergenic
ADediting_41304chr1_166898815_-intergenic
ADediting_41305chr1_166898816_-intergenic
ADediting_41306chr1_166898837_-intergenic
ADediting_41307chr1_166898838_-intergenic
ADediting_41308chr1_166898841_-intergenic
ADediting_41309chr1_166898855_-intergenic
ADediting_41310chr1_166898892_-intergenic
ADediting_41311chr1_166898893_-intergenic
ADediting_41312chr1_166898938_-intergenic
ADediting_41313chr1_166898965_-intergenic
ADediting_41314chr1_166898977_-intergenic
ADediting_41315chr1_166898984_-intergenic
ADediting_41316chr1_166899026_-intergenic
ADediting_41317chr1_166899027_-intergenic
ADediting_41318chr1_166899028_-intergenic
ADediting_41319chr1_166899054_-intergenic
ADediting_41320chr1_166899190_-intergenic
ADediting_41321chr1_166899208_-intergenic
ADediting_41322chr1_166899227_-intergenic
ADediting_41323chr1_166899230_-intergenic
ADediting_41324chr1_166899245_-intergenic
ADediting_41325chr1_166899271_-intergenic
ADediting_41326chr1_166899284_-intergenic
ADediting_41327chr1_166899293_-intergenic
ADediting_41328chr1_166899306_-intergenic
ADediting_41329chr1_166899310_-intergenic
ADediting_41330chr1_166899330_-intergenic
ADediting_41331chr1_166899349_-intergenic
ADediting_41332chr1_166901989_-intergenic
ADediting_41333chr1_166901998_-intergenic
ADediting_41334chr1_166901999_-intergenic
ADediting_41335chr1_166902025_-intergenic
ADediting_41336chr1_166902038_-intergenic
ADediting_41337chr1_166902097_-intergenic
ADediting_41338chr1_166902110_-intergenic
ADediting_41339chr1_166902132_-intergenic
ADediting_41340chr1_166902133_-intergenic
ADediting_41341chr1_166910982_-UTR3
ADediting_41342chr1_166911000_-UTR3
ADediting_41343chr1_166911013_-UTR3
ADediting_41344chr1_166911018_-UTR3
ADediting_41345chr1_166911022_-UTR3
ADediting_41346chr1_166911028_-UTR3
ADediting_41347chr1_166911035_-UTR3
ADediting_41348chr1_166911036_-UTR3
ADediting_41349chr1_166911041_-UTR3
ADediting_41350chr1_166913860_-UTR3
ADediting_41351chr1_166913887_-UTR3
ADediting_41352chr1_166913895_-UTR3
ADediting_41353chr1_166913899_-UTR3
ADediting_41354chr1_166913912_-UTR3
ADediting_41355chr1_166913913_-UTR3
ADediting_41356chr1_166913914_-UTR3
ADediting_41357chr1_166913949_-UTR3
ADediting_41358chr1_166913951_-UTR3
ADediting_41359chr1_166913985_-UTR3
ADediting_41360chr1_166913993_-UTR3
ADediting_41361chr1_166914029_-UTR3
ADediting_41362chr1_166914032_-UTR3
ADediting_41363chr1_166914033_-UTR3
ADediting_41364chr1_166914038_-UTR3
ADediting_41365chr1_166914062_-UTR3
ADediting_41366chr1_166965711_-intronic
ADediting_41367chr1_166971661_-intronic
ADediting_1516223chr1_166898936_-intergenic
ADediting_1516224chr1_166899135_-intergenic
ADediting_1516225chr1_166902092_-intergenic
ADediting_1596973chr1_166926759_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_41288chr1_166896702_-SINEAluName=AluSq2
ADediting_41289chr1_166896703_-SINEAluName=AluSq2
ADediting_41290chr1_166896704_-SINEAluName=AluSq2
ADediting_41291chr1_166896747_-SINEAluName=AluSq2
ADediting_41292chr1_166896760_-SINEAluName=AluSq2
ADediting_41293chr1_166896773_-SINEAluName=AluSq2
ADediting_41294chr1_166896774_-SINEAluName=AluSq2
ADediting_41295chr1_166896800_-SINEAluName=AluSq2
ADediting_41296chr1_166896814_-SINEAluName=AluSq2
ADediting_41297chr1_166896817_-SINEAluName=AluSq2
ADediting_41298chr1_166896834_-SINEAluName=AluSq2
ADediting_41299chr1_166896853_-SINEAluName=AluSq2
ADediting_41300chr1_166896907_-SINEAluName=AluSq2
ADediting_41301chr1_166896908_-SINEAluName=AluSq2
ADediting_41302chr1_166896914_-SINEAluName=AluSq2
ADediting_41303chr1_166898803_-SINEAluName=AluJr
ADediting_41304chr1_166898815_-SINEAluName=AluJr
ADediting_41305chr1_166898816_-SINEAluName=AluJr
ADediting_41306chr1_166898837_-SINEAluName=AluJr
ADediting_41307chr1_166898838_-SINEAluName=AluJr
ADediting_41308chr1_166898841_-SINEAluName=AluJr
ADediting_41309chr1_166898855_-SINEAluName=AluJr
ADediting_41310chr1_166898892_-SINEAluName=AluJr
ADediting_41311chr1_166898893_-SINEAluName=AluJr
ADediting_41312chr1_166898938_-SINEAluName=AluJr
ADediting_41313chr1_166898965_-SINEAluName=AluJr
ADediting_41314chr1_166898977_-SINEAluName=AluJr
ADediting_41315chr1_166898984_-SINEAluName=AluJr
ADediting_41316chr1_166899026_-SINEAluName=AluJr
ADediting_41317chr1_166899027_-SINEAluName=AluJr
ADediting_41318chr1_166899028_-SINEAluName=AluJr
ADediting_41319chr1_166899054_-SINEAluName=AluJr
ADediting_41320chr1_166899190_-SINEAluName=AluSx1
ADediting_41321chr1_166899208_-SINEAluName=AluSx1
ADediting_41322chr1_166899227_-SINEAluName=AluSx1
ADediting_41323chr1_166899230_-SINEAluName=AluSx1
ADediting_41324chr1_166899245_-SINEAluName=AluSx1
ADediting_41325chr1_166899271_-SINEAluName=AluSx1
ADediting_41326chr1_166899284_-SINEAluName=AluSx1
ADediting_41327chr1_166899293_-SINEAluName=AluSx1
ADediting_41328chr1_166899306_-SINEAluName=AluSx1
ADediting_41329chr1_166899310_-SINEAluName=AluSx1
ADediting_41330chr1_166899330_-SINEAluName=AluSx1
ADediting_41331chr1_166899349_-SINEAluName=AluSx1
ADediting_41332chr1_166901989_-SINEAluName=AluSp
ADediting_41333chr1_166901998_-SINEAluName=AluSp
ADediting_41334chr1_166901999_-SINEAluName=AluSp
ADediting_41335chr1_166902025_-SINEAluName=AluSp
ADediting_41336chr1_166902038_-SINEAluName=AluSp
ADediting_41337chr1_166902097_-SINEAluName=AluSp
ADediting_41338chr1_166902110_-SINEAluName=AluSp
ADediting_41339chr1_166902132_-SINEAluName=AluSp
ADediting_41340chr1_166902133_-SINEAluName=AluSp
ADediting_41341chr1_166910982_-SINEAluName=AluJr4
ADediting_41342chr1_166911000_-SINEAluName=AluJr4
ADediting_41343chr1_166911013_-SINEAluName=AluJr4
ADediting_41344chr1_166911018_-SINEAluName=AluJr4
ADediting_41345chr1_166911022_-SINEAluName=AluJr4
ADediting_41346chr1_166911028_-SINEAluName=AluJr4
ADediting_41347chr1_166911035_-SINEAluName=AluJr4
ADediting_41348chr1_166911036_-SINEAluName=AluJr4
ADediting_41349chr1_166911041_-SINEAluName=AluJr4
ADediting_41350chr1_166913860_-SINEAluName=AluJo
ADediting_41351chr1_166913887_-SINEAluName=AluJo
ADediting_41352chr1_166913895_-SINEAluName=AluJo
ADediting_41353chr1_166913899_-SINEAluName=AluJo
ADediting_41354chr1_166913912_-SINEAluName=AluJo
ADediting_41355chr1_166913913_-SINEAluName=AluJo
ADediting_41356chr1_166913914_-SINEAluName=AluJo
ADediting_41357chr1_166913949_-SINEAluName=AluJo
ADediting_41358chr1_166913951_-SINEAluName=AluJo
ADediting_41359chr1_166913985_-SINEAluName=AluJo
ADediting_41360chr1_166913993_-SINEAluName=AluJo
ADediting_41361chr1_166914029_-SINEAluName=AluJo
ADediting_41362chr1_166914032_-SINEAluName=AluJo
ADediting_41363chr1_166914033_-SINEAluName=AluJo
ADediting_41364chr1_166914038_-SINEAluName=AluJo
ADediting_41365chr1_166914062_-SINEAluName=AluJo
ADediting_41366chr1_166965711_-SINEAluName=AluSx3
ADediting_41367chr1_166971661_-SINEAluName=AluJb
ADediting_1516223chr1_166898936_-SINEAluName=AluJr
ADediting_1516224chr1_166899135_-SINEAluName=AluSx1
ADediting_1516225chr1_166902092_-SINEAluName=AluSp

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RNA A-to-I editing events in the alternative splicing sites for ILDR2

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ILDR2

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for ILDR2

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for ILDR2

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_41342chr1_166911000_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-5196-3pchr11669110001669110067mer-m8166910999166911018146-17.64
ADediting_41343chr1_166911013_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-6888-3pchr11669110121669110187mer-m8166911011166911034155-16.91
ADediting_41344chr1_166911018_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-2355-3pchr11669110121669110187mer-1a166911012166911036146-20.1
ADediting_41344chr1_166911018_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-4646-3pchr11669110121669110198mer-1a166911012166911032155-17.23
ADediting_41345chr1_166911022_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-6793-3pchr11669110181669110258mer-1a166911018166911037141-17.7
ADediting_41346chr1_166911028_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-3692-5pchr11669110251669110317mer-m8166911024166911052160-26.16
ADediting_41346chr1_166911028_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-6506-5pchr11669110281669110347mer-m8166911027166911049152-15.05
ADediting_41347chr1_166911035_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-4695-3pchr11669110321669110387mer-m8166911031166911052140-12.06
ADediting_41352chr1_166913895_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-1255b-2-3pchr11669138941669139007mer-m8166913893166913914140-9.3
ADediting_41352chr1_166913895_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-4751chr11669138901669138967mer-m8166913889166913912158-22.8
ADediting_41353chr1_166913899_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-3622a-3pchr11669138951669139028mer-1a166913895166913916140-15.99
ADediting_41353chr1_166913899_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-3622b-3pchr11669138951669139028mer-1a166913895166913915149-20.31
ADediting_41353chr1_166913899_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-4649-3pchr11669138991669139057mer-m8166913898166913918147-18.42
ADediting_41353chr1_166913899_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-544bchr11669138981669139047mer-m8166913897166913918154-18.39
ADediting_41354chr1_166913912_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-28-5pchr11669139071669139137mer-m8166913906166913931142-16.86
ADediting_41354chr1_166913912_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-3139chr11669139071669139137mer-m8166913906166913928165-23.54
ADediting_41354chr1_166913912_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-708-5pchr11669139071669139137mer-m8166913906166913931153-22.79
ADediting_41355chr1_166913913_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-4294chr11669139081669139147mer-m8166913907166913923143-17.86
ADediting_41355chr1_166913913_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-4329chr11669139121669139198mer-1a166913912166913930140-12.64
ADediting_41360chr1_166913993_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-17-3pchr11669139891669139968mer-1a166913989166914011150-17.21
ADediting_41360chr1_166913993_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-1910-5pchr11669139931669139997mer-m8166913992166914010149-19.42
ADediting_41364chr1_166914038_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-4433a-3pchr11669140381669140447mer-m8166914037166914059146-20.9
ADediting_41364chr1_166914038_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-665chr11669140371669140437mer-m8166914036166914055160-24.7
ADediting_41364chr1_166914038_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-6807-5pchr11669140321669140398mer-1a166914032166914052158-22.03
ADediting_41365chr1_166914062_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-4537chr11669140571669140648mer-1a166914057166914078140-25.25

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_41342chr1_166911000_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-9903chr11669110001669110067mer-m8166910999166911020145-16.71
ADediting_41344chr1_166911018_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-6867-3pchr11669110161669110227mer-m8166911015166911035140-11.25
ADediting_41346chr1_166911028_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-6513-5pchr11669110281669110347mer-m8166911027166911049145-14.3
ADediting_41347chr1_166911035_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-205-3pchr11669110331669110397mer-m8166911032166911055151-17.25
ADediting_41347chr1_166911035_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-3167chr11669110311669110377mer-m8166911030166911051150-14.78
ADediting_41348chr1_166911036_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-205-3pchr11669110331669110397mer-m8166911032166911055151-17.25
ADediting_41348chr1_166911036_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-3167chr11669110311669110377mer-m8166911030166911051150-14.78
ADediting_41349chr1_166911041_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-3934-5pchr11669110361669110438mer-1a166911036166911057153-26.47
ADediting_41350chr1_166913860_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-2054chr11669138581669138647mer-m8166913857166913877150-11.94
ADediting_41350chr1_166913860_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-3686chr11669138561669138627mer-m8166913855166913875143-10.59
ADediting_41351chr1_166913887_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-1233-5pchr11669138861669138927mer-m8166913885166913906145-22.05
ADediting_41351chr1_166913887_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-1273h-5pchr11669138871669138937mer-m8166913886166913911147-22.44
ADediting_41351chr1_166913887_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-30b-3pchr11669138871669138937mer-m8166913886166913907140-15.74
ADediting_41351chr1_166913887_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-3689a-3pchr11669138871669138937mer-m8166913886166913906142-16.13
ADediting_41351chr1_166913887_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-3689b-3pchr11669138871669138937mer-m8166913886166913905148-20.01
ADediting_41351chr1_166913887_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-3689cchr11669138871669138937mer-m8166913886166913905148-20.01
ADediting_41351chr1_166913887_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-4761-5pchr11669138821669138887mer-m8166913881166913904145-11.67
ADediting_41351chr1_166913887_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-6779-5pchr11669138871669138937mer-m8166913886166913906143-20.65
ADediting_41351chr1_166913887_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-6780a-5pchr11669138871669138937mer-m8166913886166913908141-19.09
ADediting_41357chr1_166913949_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-3675-3pchr11669139461669139527mer-m8166913945166913966144-13.72
ADediting_41358chr1_166913951_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-3675-3pchr11669139461669139527mer-m8166913945166913966144-13.72
ADediting_41360chr1_166913993_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-20b-3pchr11669139891669139968mer-1a166913989166914011149-14.3
ADediting_41365chr1_166914062_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-3160-3pchr11669140571669140648mer-1a166914057166914078145-15.63

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-589-3pchr11669140981669141047mer-m8166914097166914120158-17.61
ADediting_1471003chr9_63819626_+ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-4477bchr11669141911669141988mer-1a166914191166914214151-11.11
ADediting_1631458chr19_40282624_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-641chr11669087641669087707mer-m8166908763166908786142-13.03
ADediting_1631458chr19_40282624_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-641chr11669131071669131137mer-m8166913106166913132149-13.01
ADediting_1631458chr19_40282624_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-641chr11669153021669153087mer-m8166915301166915327153-15.49
ADediting_286380chr11_79422188_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-5579-3pchr11669081871669081937mer-m8166908187166908204156-13.76
ADediting_843620chr2_207754818_+ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-4775chr11669148721669148787mer-m8166914871166914892140-5.83
ADediting_843620chr2_207754818_+ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-4775chr11669188191669188268mer-1a166918819166918844146-16.25
ADediting_98289chr1_32086992_+ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-5585-3pchr11669142001669142067mer-m8166914199166914219141-10.98

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1097295chr3_85385762_+ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-5688chr11669115511669115588mer-1a166911551166911569150-10.91
ADediting_1097295chr3_85385762_+ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-5688chr11669139551669139617mer-m8166913954166913975145-9.66
ADediting_1337757chr7_5495852_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-589-3pchr11669187491669187568mer-1a166918749166918772140-13.25
ADediting_1337758chr7_5495892_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-589-5pchr11669107611669107677mer-m8166910760166910782141-15.82
ADediting_1471003chr9_63819626_+ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-4477bchr11669143631669143708mer-1a166914363166914383151-9.81
ADediting_1471004chr9_63819627_+ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-4477bchr11669143631669143708mer-1a166914363166914383151-9.81
ADediting_1596844chr1_162342605_+ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-556-3pchr11669137951669138017mer-m8166913794166913818148-13.76
ADediting_1643790chr3_121049689_+ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-5682chr11669140651669140717mer-m8166914064166914086152-18.96
ADediting_286380chr11_79422188_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-5579-3pchr11669129991669130057mer-m8166912998166913019140-10.69
ADediting_291761chr11_93733708_-ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-1304-3pchr11669092871669092937mer-m8166909286166909306141-14.46
ADediting_527135chr16_24203190_+ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-1273h-3pchr11669082901669082978mer-1a166908290166908312147-16.3
ADediting_843620chr2_207754818_+ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-4775chr11669107011669107077mer-m8166910700166910720148-5.05
ADediting_843620chr2_207754818_+ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-4775chr11669108641669108707mer-m8166910863166910886143-8.86
ADediting_843620chr2_207754818_+ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-4775chr11669144151669144217mer-m8166914414166914435140-5.82
ADediting_98288chr1_32086990_+ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-5585-3pchr11669118321669118387mer-m8166911831166911849148-13.99
ADediting_98289chr1_32086992_+ENSG00000143195.13ENST00000271417.8ILDR2-201hsa-miR-5585-3pchr11669118321669118387mer-m8166911831166911849148-13.99

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ILDR2

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000271417.8protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_41341ENST00000271417.8chr1_166910982_-10565-4159.00-4155.90-4198.40
ADediting_41342ENST00000271417.8chr1_166911000_-10547-4158.50-4155.90-4198.40
ADediting_41343ENST00000271417.8chr1_166911013_-10534-4156.30-4155.90-4198.40
ADediting_41344ENST00000271417.8chr1_166911018_-10529-4155.90-4155.90-4198.40
ADediting_41345ENST00000271417.8chr1_166911022_-10525-4155.60-4155.90-4198.40
ADediting_41346ENST00000271417.8chr1_166911028_-10519-4162.60-4155.90-4198.40
ADediting_41347ENST00000271417.8chr1_166911035_-10512-4155.90-4155.90-4198.40
ADediting_41348ENST00000271417.8chr1_166911036_-10511-4156.50-4155.90-4198.40
ADediting_41349ENST00000271417.8chr1_166911041_-10506-4156.90-4155.90-4198.40
ADediting_41350ENST00000271417.8chr1_166913860_-7687-4155.90-4155.90-4198.40
ADediting_41351ENST00000271417.8chr1_166913887_-7660-4155.50-4155.90-4198.40
ADediting_41352ENST00000271417.8chr1_166913895_-7652-4156.20-4155.90-4198.40
ADediting_41353ENST00000271417.8chr1_166913899_-7648-4155.60-4155.90-4198.40
ADediting_41354ENST00000271417.8chr1_166913912_-7635-4155.90-4155.90-4198.40
ADediting_41355ENST00000271417.8chr1_166913913_-7634-4155.90-4155.90-4198.40
ADediting_41356ENST00000271417.8chr1_166913914_-7633-4159.00-4155.90-4198.40
ADediting_41357ENST00000271417.8chr1_166913949_-7598-4158.10-4155.90-4198.40
ADediting_41358ENST00000271417.8chr1_166913951_-7596-4162.50-4155.90-4198.40
ADediting_41359ENST00000271417.8chr1_166913985_-7562-4158.80-4155.90-4198.40
ADediting_41360ENST00000271417.8chr1_166913993_-7554-4158.20-4155.90-4198.40
ADediting_41361ENST00000271417.8chr1_166914029_-7518-4155.60-4155.90-4198.40
ADediting_41362ENST00000271417.8chr1_166914032_-7515-4158.00-4155.90-4198.40
ADediting_41363ENST00000271417.8chr1_166914033_-7514-4156.70-4155.90-4198.40
ADediting_41364ENST00000271417.8chr1_166914038_-7509-4157.80-4155.90-4198.40
ADediting_41365ENST00000271417.8chr1_166914062_-7485-4155.90-4155.90-4198.40

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for ILDR2

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_41293chr1_166896773_-0.0003706735526335890.2009471354376290.05840375050888020.107617951524655.53671959389375e-080.302542883816744
DLPFCADediting_41294chr1_166896774_-1.94048156247788e-050.2400260672326750.01359806608536240.1400309388694092.55888056866919e-090.330169803591901
CERADediting_41304chr1_166898815_-0.05619573364300130.1562592767674470.0001034508101079850.3116674215684980.8669726261806910.0137914567347547
CERADediting_41305chr1_166898816_-0.02355806166768510.1848265027793467.69898728605214e-050.3170905292103150.4118419330662680.0674944942042859
TCXADediting_41309chr1_166898855_-0.002556659700773690.2445943704379879.51359424713364e-050.3132161690338680.36643254433821-0.0742633568564351
TCXADediting_41312chr1_166898938_-0.0002458771729450470.2951417856174520.0001268248719853450.3078660887474870.507160195059327-0.0545715849442087
DLPFCADediting_41313chr1_166898965_-1.3516672520842e-110.3717602572117292.3333174431373e-060.2644792797601181.83638408006652e-050.240695574551871
CERADediting_41313chr1_166898965_-0.02124420428844530.1879819835173728.72772358514667e-050.314800960952950.990830173946729-0.000946309590711836
DLPFCADediting_41314chr1_166898977_-1.30392373518753e-090.3358729836891140.0001332761719635680.2152995923176430.01164708834650.143117327445606
DLPFCADediting_41316chr1_166899026_-3.98636730849822e-090.3263547415576480.0004465590704613120.1982253213993642.00830188141033e-100.351115564735157
DLPFCADediting_41318chr1_166899028_-2.18482401908178e-060.2652002135429790.02103025623138360.1310177132882893.65978105547024e-130.397264932379849
DLPFCADediting_41322chr1_166899227_-6.93339784645549e-070.2774589566661520.003837231153158270.1637630390757217.32089109809742e-100.340664993002553
DLPFCADediting_41323chr1_166899230_-2.97743154147728e-060.2617880478123050.01669190928341610.1358553895977591.93166517782764e-080.312326060744767
TCXADediting_41341chr1_166910982_-4.27158160658457e-070.3989234356541923.60750201367843e-050.3305510616185730.13099561076938-0.123867119401032
TCXADediting_41342chr1_166911000_-0.001586458810435190.2557186562422672.4369935140455e-050.3372760321029660.187263474598038-0.108261758969645
CERADediting_41352chr1_166913895_-0.005574447853193020.2252855247358174.05343157638076e-050.3285223182863620.7691844570830540.0241580205902455
CERADediting_41353chr1_166913899_-0.0002089399090276210.2983251770335179.44278230963845e-080.4190539057849550.46751693808990.0597674482704975
CERADediting_41355chr1_166913913_-1.50193034888939e-060.3810771331543032.51969054647453e-100.4874302312856770.28826764169810.087270698482769
TCXADediting_41355chr1_166913913_-0.000309923171944710.2905502764236042.63046687430081e-120.5313891782980950.04096930311946-0.167101537401175
IFGADediting_41355chr1_166913913_-0.08751746824440190.3487587819712290.01807983207719550.4688226381850510.3795118340379530.183660050506676
CERADediting_41356chr1_166913914_-0.0006132357106424350.2765447092601445.32991350596905e-060.3619651424142240.437861715602360.0638137800100965
CERADediting_41358chr1_166913951_-2.35482839415219e-080.4364819468914492.9921068613858e-070.4037921260592890.07966912057765760.143558687250566
TCXADediting_41358chr1_166913951_-3.19944973569274e-050.3326257026007471.54227796012902e-060.3806893272454950.232109860708348-0.0981518791430033
IFGADediting_41358chr1_166913951_-0.002056896569068020.5865761634652120.002622798825362510.5753155799569530.0182955610598130.468054348693662
CERADediting_41359chr1_166913985_-0.01660009739629280.1953335893561961.15516478423844e-060.3848907465146640.07708840356806750.144792785124533

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC9.4176651716159e-250.5389327461642551.75704544155643e-270.5644635514355670.325254735383037-0.0560538692879271
AC1.05988062345342e-310.6524192373391638.28917592437899e-250.5896959603714035.34099681159071e-050.252632482422536
PCC4.44407347836523e-230.6363983629925696.59472419397239e-230.6344536379898280.01418329775114950.177219323082408
CER3.2057910091011e-050.3325916017318153.14649634198322e-090.4601183428076010.005106150035875360.227536699766511
TCX1.33450109862432e-060.3828001588317946.08400498055494e-060.3598960181439530.664489153797506-0.0357007451252061
FP1.07992237966531e-240.6715391032198744.47137312578631e-290.7142257077937438.19175923875246e-050.290860345420146
IFG6.77867718921877e-050.711024221883430.0001407660208896040.6887471751486780.944286222250764-0.014730160199897
PG1.99222440755028e-530.8512964157212281.02071381552857e-280.70008157019930.63219193059775-0.0353230464444362
STG3.76928130776759e-200.8033559310016023.20340985247965e-160.7473737159519730.2957751754504550.11542506257566

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Relation with AD stages for ILDR2

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_41355chr1_166913913_-0.0008051111310298930.317751246108738
CERADediting_41356chr1_166913914_-0.0004053275835182050.334350492356059
TCXADediting_41308chr1_166898841_-0.0004833474967992750.333173218251414
IFGADediting_41342chr1_166911000_-0.04897706951583-0.397704204776515
IFGADediting_41352chr1_166913895_-0.00684563398877336-0.526584349793649

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER2.12729870808112e-060.438024863605775
TCX0.0002715131860322770.346726085914306
STG0.00246650866258718-0.32612399497213

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RelatedDrugs for ILDR2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ILDR2

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource