ADeditome: functional annotation of RNA A-to-I editing in AD

Gene summary for STUM

Gene summary

Gene information	Gene symbol	STUM
	Gene ID	375057
	Gene name	stum, mechanosensory transduction mediator homolog
	Synonyms	C1orf95
	Cytomap	1q42.12
	Type of gene	protein-coding
	Description	protein stum homologstumble homolog
	Modification date	20200313
	UniProtAcc	Q69YW2,
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for STUM

RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA editing frequencies across three data sets.

The number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA A-to-I editing events in AD.

ADediting_71250(226570973, +), ADediting_71277(226592952, +), ADediting_71278(226592953, +), ADediting_71279(226592976, +), ADediting_71280(226592985, +), ADediting_71281(226600214, +), ADediting_71282(226604124, +), ADediting_71283(226604131, +), ADediting_71284(226604134, +), ADediting_71285(226604151, +), ADediting_71286(226604164, +), ADediting_71287(226604169, +), ADediting_71288(226604201, +), ADediting_71289(226604209, +), ADediting_71290(226604210, +), ADediting_71291(226604212, +), ADediting_71292(226604213, +), ADediting_71293(226604219, +), ADediting_71294(226604222, +), ADediting_71295(226604223, +), ADediting_71296(226604227, +), ADediting_71297(226604240, +), ADediting_71298(226604248, +), ADediting_71299(226604249, +), ADediting_71300(226604906, +), ADediting_71301(226605513, +), ADediting_71302(226605518, +), ADediting_71303(226605540, +), ADediting_71304(226605560, +), ADediting_71305(226605563, +), ADediting_71306(226605564, +), ADediting_71307(226605565, +), ADediting_71308(226605571, +), ADediting_71309(226605572, +), ADediting_71310(226605574, +), ADediting_71311(226605576, +), ADediting_71312(226605577, +), ADediting_71313(226605578, +), ADediting_71314(226605581, +), ADediting_71315(226605584, +), ADediting_71316(226605603, +), ADediting_71317(226605606, +), ADediting_71318(226605622, +), ADediting_71319(226605630, +), ADediting_71320(226605631, +), ADediting_71321(226605632, +), ADediting_71322(226605634, +), ADediting_71323(226605635, +), ADediting_71324(226605651, +), ADediting_71325(226605682, +), ADediting_71326(226605685, +), ADediting_1599276(226571055, +),

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RNA editing positional annotations for STUM using Annovar

Protein coding RNA editing(s).

ADeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

ADeditome ID	Position	Variant type
ADediting_71250	chr1_226570973_+	intronic
ADediting_71277	chr1_226592952_+	intronic
ADediting_71278	chr1_226592953_+	intronic
ADediting_71279	chr1_226592976_+	intronic
ADediting_71280	chr1_226592985_+	intronic
ADediting_71281	chr1_226600214_+	intronic
ADediting_71282	chr1_226604124_+	UTR3
ADediting_71283	chr1_226604131_+	UTR3
ADediting_71284	chr1_226604134_+	UTR3
ADediting_71285	chr1_226604151_+	UTR3
ADediting_71286	chr1_226604164_+	UTR3
ADediting_71287	chr1_226604169_+	UTR3
ADediting_71288	chr1_226604201_+	UTR3
ADediting_71289	chr1_226604209_+	UTR3
ADediting_71290	chr1_226604210_+	UTR3
ADediting_71291	chr1_226604212_+	UTR3
ADediting_71292	chr1_226604213_+	UTR3
ADediting_71293	chr1_226604219_+	UTR3
ADediting_71294	chr1_226604222_+	UTR3
ADediting_71295	chr1_226604223_+	UTR3
ADediting_71296	chr1_226604227_+	UTR3
ADediting_71297	chr1_226604240_+	UTR3
ADediting_71298	chr1_226604248_+	UTR3
ADediting_71299	chr1_226604249_+	UTR3
ADediting_71300	chr1_226604906_+	UTR3
ADediting_71301	chr1_226605513_+	UTR3
ADediting_71302	chr1_226605518_+	UTR3
ADediting_71303	chr1_226605540_+	UTR3
ADediting_71304	chr1_226605560_+	UTR3
ADediting_71305	chr1_226605563_+	UTR3
ADediting_71306	chr1_226605564_+	UTR3
ADediting_71307	chr1_226605565_+	UTR3
ADediting_71308	chr1_226605571_+	UTR3
ADediting_71309	chr1_226605572_+	UTR3
ADediting_71310	chr1_226605574_+	UTR3
ADediting_71311	chr1_226605576_+	UTR3
ADediting_71312	chr1_226605577_+	UTR3
ADediting_71313	chr1_226605578_+	UTR3
ADediting_71314	chr1_226605581_+	UTR3
ADediting_71315	chr1_226605584_+	UTR3
ADediting_71316	chr1_226605603_+	UTR3
ADediting_71317	chr1_226605606_+	UTR3
ADediting_71318	chr1_226605622_+	UTR3
ADediting_71319	chr1_226605630_+	UTR3
ADediting_71320	chr1_226605631_+	UTR3
ADediting_71321	chr1_226605632_+	UTR3
ADediting_71322	chr1_226605634_+	UTR3
ADediting_71323	chr1_226605635_+	UTR3
ADediting_71324	chr1_226605651_+	UTR3
ADediting_71325	chr1_226605682_+	UTR3
ADediting_71326	chr1_226605685_+	UTR3
ADediting_1599276	chr1_226571055_+	intronic

Repat-regional RNA editing(s).

ADeditome ID	Position	Repeat family	Repeat sub family	Repeat name
ADediting_71250	chr1_226570973_+	SINE	Alu	Name=AluSx1
ADediting_71277	chr1_226592952_+	SINE	Alu	Name=AluSz
ADediting_71278	chr1_226592953_+	SINE	Alu	Name=AluSz
ADediting_71279	chr1_226592976_+	SINE	Alu	Name=AluSz
ADediting_71280	chr1_226592985_+	SINE	Alu	Name=AluSz
ADediting_71281	chr1_226600214_+	SINE	Alu	Name=AluJo
ADediting_1599276	chr1_226571055_+	SINE	Alu	Name=AluSx1

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RNA A-to-I editing events in the alternative splicing sites for STUM

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

ADeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for STUM

Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

- Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

ADeditome ID

Chr

Positoing

Skipped exon

ENSG

ENSTs

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Protein coding region RNA A-to-I editings for STUM

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for STUM

RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

ADeditom_ID	Position	ENSG	ENST	Transcript name	miRNA ID	Chromosome	Targt	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
ADediting_71283	chr1_226604131_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4740-3p	chr1	226604126	226604133	8mer-1a	226604112	226604133	148	-20.04
ADediting_71283	chr1_226604131_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4740-3p	chr1	226604126	226604133	8mer-1a	226604112	226604133	148	-20.04
ADediting_71284	chr1_226604134_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-125b-5p	chr1	226604127	226604133	7mer-m8	226604113	226604134	155	-23.95
ADediting_71284	chr1_226604134_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4319	chr1	226604127	226604133	7mer-m8	226604118	226604134	140	-16.8
ADediting_71284	chr1_226604134_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-125b-5p	chr1	226604127	226604133	7mer-m8	226604113	226604134	155	-23.95
ADediting_71284	chr1_226604134_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4319	chr1	226604127	226604133	7mer-m8	226604118	226604134	140	-16.8
ADediting_71285	chr1_226604151_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-134-3p	chr1	226604144	226604151	8mer-1a	226604127	226604151	141	-18.21
ADediting_71285	chr1_226604151_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-134-3p	chr1	226604144	226604151	8mer-1a	226604127	226604151	141	-18.21
ADediting_71286	chr1_226604164_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-7109-3p	chr1	226604161	226604168	8mer-1a	226604146	226604168	161	-22.23
ADediting_71286	chr1_226604164_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-7109-3p	chr1	226604161	226604168	8mer-1a	226604146	226604168	161	-22.23
ADediting_71287	chr1_226604169_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-570-3p	chr1	226604167	226604173	7mer-m8	226604152	226604174	151	-12.28
ADediting_71287	chr1_226604169_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-570-3p	chr1	226604167	226604173	7mer-m8	226604152	226604174	151	-12.28
ADediting_71288	chr1_226604201_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-361-3p	chr1	226604197	226604203	7mer-m8	226604182	226604204	144	-22.89
ADediting_71288	chr1_226604201_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4530	chr1	226604194	226604200	7mer-m8	226604184	226604201	140	-20.94
ADediting_71288	chr1_226604201_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-361-3p	chr1	226604197	226604203	7mer-m8	226604182	226604204	144	-22.89
ADediting_71288	chr1_226604201_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4530	chr1	226604194	226604200	7mer-m8	226604184	226604201	140	-20.94
ADediting_71290	chr1_226604210_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-670-3p	chr1	226604206	226604212	7mer-m8	226604195	226604213	152	-20.49
ADediting_71290	chr1_226604210_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-6784-3p	chr1	226604203	226604209	7mer-m8	226604185	226604210	154	-34.44
ADediting_71290	chr1_226604210_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-6862-3p	chr1	226604203	226604209	7mer-m8	226604188	226604210	154	-30.56
ADediting_71290	chr1_226604210_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-670-3p	chr1	226604206	226604212	7mer-m8	226604195	226604213	152	-20.49
ADediting_71290	chr1_226604210_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-6784-3p	chr1	226604203	226604209	7mer-m8	226604185	226604210	154	-34.44
ADediting_71290	chr1_226604210_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-6862-3p	chr1	226604203	226604209	7mer-m8	226604188	226604210	154	-30.56
ADediting_71291	chr1_226604212_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-205-5p	chr1	226604206	226604212	7mer-1a	226604190	226604212	147	-29.13
ADediting_71291	chr1_226604212_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-6845-3p	chr1	226604209	226604216	8mer-1a	226604199	226604216	143	-19.96
ADediting_71291	chr1_226604212_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-205-5p	chr1	226604206	226604212	7mer-1a	226604190	226604212	147	-29.13
ADediting_71291	chr1_226604212_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-6845-3p	chr1	226604209	226604216	8mer-1a	226604199	226604216	143	-19.96
ADediting_71292	chr1_226604213_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4279	chr1	226604210	226604216	7mer-m8	226604202	226604217	140	-13.37
ADediting_71292	chr1_226604213_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-6515-3p	chr1	226604206	226604212	7mer-m8	226604194	226604213	151	-27.04
ADediting_71292	chr1_226604213_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-6881-3p	chr1	226604208	226604214	7mer-m8	226604194	226604215	157	-19.66
ADediting_71292	chr1_226604213_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-877-3p	chr1	226604207	226604214	8mer-1a	226604195	226604214	163	-28.67
ADediting_71292	chr1_226604213_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4279	chr1	226604210	226604216	7mer-m8	226604202	226604217	140	-13.37
ADediting_71292	chr1_226604213_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-6515-3p	chr1	226604206	226604212	7mer-m8	226604194	226604213	151	-27.04
ADediting_71292	chr1_226604213_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-6881-3p	chr1	226604208	226604214	7mer-m8	226604194	226604215	157	-19.66
ADediting_71292	chr1_226604213_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-877-3p	chr1	226604207	226604214	8mer-1a	226604195	226604214	163	-28.67
ADediting_71293	chr1_226604219_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4776-3p	chr1	226604216	226604222	7mer-m8	226604200	226604223	160	-19.51
ADediting_71293	chr1_226604219_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4776-3p	chr1	226604216	226604222	7mer-m8	226604200	226604223	160	-19.51
ADediting_71295	chr1_226604223_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-548av-3p	chr1	226604219	226604226	8mer-1a	226604207	226604226	162	-12.16
ADediting_71295	chr1_226604223_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-548g-3p	chr1	226604220	226604226	7mer-1a	226604205	226604226	150	-12.38
ADediting_71295	chr1_226604223_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-548av-3p	chr1	226604219	226604226	8mer-1a	226604207	226604226	162	-12.16
ADediting_71295	chr1_226604223_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-548g-3p	chr1	226604220	226604226	7mer-1a	226604205	226604226	150	-12.38
ADediting_71296	chr1_226604227_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4719	chr1	226604222	226604228	7mer-m8	226604206	226604229	147	-9.28
ADediting_71296	chr1_226604227_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4719	chr1	226604222	226604228	7mer-m8	226604206	226604229	147	-9.28
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-1269a	chr1	226604246	226604252	7mer-m8	226604232	226604253	147	-19.57
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-1269b	chr1	226604246	226604252	7mer-m8	226604232	226604253	151	-19.57
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-378a-3p	chr1	226604247	226604254	8mer-1a	226604235	226604254	149	-18.17
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-378b	chr1	226604247	226604254	8mer-1a	226604235	226604254	141	-13.35
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-378c	chr1	226604247	226604254	8mer-1a	226604232	226604254	154	-18.67
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-378d	chr1	226604247	226604254	8mer-1a	226604237	226604254	149	-16.77
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-378e	chr1	226604247	226604254	8mer-1a	226604238	226604254	149	-16.77
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-378f	chr1	226604247	226604254	8mer-1a	226604234	226604254	149	-14.62
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-378h	chr1	226604247	226604254	8mer-1a	226604236	226604254	157	-20.25
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-378i	chr1	226604247	226604254	8mer-1a	226604236	226604254	149	-16.77
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-422a	chr1	226604247	226604254	8mer-1a	226604235	226604254	149	-17.89
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-892a	chr1	226604243	226604249	7mer-m8	226604227	226604250	149	-20.55
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-1269a	chr1	226604246	226604252	7mer-m8	226604232	226604253	147	-19.57
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-1269b	chr1	226604246	226604252	7mer-m8	226604232	226604253	151	-19.57
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-378a-3p	chr1	226604247	226604254	8mer-1a	226604235	226604254	149	-18.17
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-378b	chr1	226604247	226604254	8mer-1a	226604235	226604254	141	-13.35
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-378c	chr1	226604247	226604254	8mer-1a	226604232	226604254	154	-18.67
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-378d	chr1	226604247	226604254	8mer-1a	226604237	226604254	149	-16.77
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-378e	chr1	226604247	226604254	8mer-1a	226604238	226604254	149	-16.77
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-378f	chr1	226604247	226604254	8mer-1a	226604234	226604254	149	-14.62
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-378h	chr1	226604247	226604254	8mer-1a	226604236	226604254	157	-20.25
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-378i	chr1	226604247	226604254	8mer-1a	226604236	226604254	149	-16.77
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-422a	chr1	226604247	226604254	8mer-1a	226604235	226604254	149	-17.89
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-892a	chr1	226604243	226604249	7mer-m8	226604227	226604250	149	-20.55
ADediting_71300	chr1_226604906_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-12133	chr1	226604903	226604910	8mer-1a	226604889	226604910	140	-9.9
ADediting_71300	chr1_226604906_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-1271-5p	chr1	226604903	226604910	8mer-1a	226604890	226604910	147	-17.47
ADediting_71300	chr1_226604906_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-182-5p	chr1	226604904	226604910	7mer-1a	226604886	226604910	143	-21.02
ADediting_71300	chr1_226604906_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-96-5p	chr1	226604903	226604910	8mer-1a	226604885	226604910	163	-21.68
ADediting_71300	chr1_226604906_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-12133	chr1	226604903	226604910	8mer-1a	226604889	226604910	140	-9.9
ADediting_71300	chr1_226604906_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-1271-5p	chr1	226604903	226604910	8mer-1a	226604890	226604910	147	-17.47
ADediting_71300	chr1_226604906_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-182-5p	chr1	226604904	226604910	7mer-1a	226604886	226604910	143	-21.02
ADediting_71300	chr1_226604906_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-96-5p	chr1	226604903	226604910	8mer-1a	226604885	226604910	163	-21.68
ADediting_71302	chr1_226605518_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-3683	chr1	226605512	226605519	8mer-1a	226605498	226605519	140	-14.2
ADediting_71302	chr1_226605518_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-3683	chr1	226605512	226605519	8mer-1a	226605498	226605519	140	-14.2
ADediting_71303	chr1_226605540_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-3937	chr1	226605537	226605543	7mer-m8	226605520	226605544	156	-21.54
ADediting_71303	chr1_226605540_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-3937	chr1	226605537	226605543	7mer-m8	226605520	226605544	156	-21.54
ADediting_71305	chr1_226605563_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4276	chr1	226605557	226605564	8mer-1a	226605548	226605564	152	-13.87
ADediting_71305	chr1_226605563_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-5190	chr1	226605556	226605563	8mer-1a	226605542	226605563	152	-16.03
ADediting_71305	chr1_226605563_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4276	chr1	226605557	226605564	8mer-1a	226605548	226605564	152	-13.87
ADediting_71305	chr1_226605563_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-5190	chr1	226605556	226605563	8mer-1a	226605542	226605563	152	-16.03
ADediting_71311	chr1_226605576_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4760-3p	chr1	226605573	226605580	8mer-1a	226605559	226605580	161	-11
ADediting_71311	chr1_226605576_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4760-3p	chr1	226605573	226605580	8mer-1a	226605559	226605580	161	-11
ADediting_71317	chr1_226605606_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-1199-3p	chr1	226605604	226605610	7mer-m8	226605591	226605611	147	-19.32
ADediting_71317	chr1_226605606_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-1908-3p	chr1	226605603	226605609	7mer-m8	226605590	226605610	143	-17.86
ADediting_71318	chr1_226605622_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-661	chr1	226605617	226605623	7mer-m8	226605599	226605624	147	-23.84
ADediting_71318	chr1_226605622_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-6849-3p	chr1	226605620	226605626	7mer-m8	226605606	226605627	147	-15.88
ADediting_71318	chr1_226605622_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-6852-5p	chr1	226605616	226605622	7mer-m8	226605603	226605623	145	-20.68
ADediting_71318	chr1_226605622_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-7155-5p	chr1	226605615	226605621	7mer-m8	226605605	226605622	145	-22.45
ADediting_71319	chr1_226605630_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4713-5p	chr1	226605624	226605631	8mer-1a	226605609	226605631	141	-16.59
ADediting_71319	chr1_226605630_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-629-3p	chr1	226605625	226605631	7mer-m8	226605611	226605632	149	-13.8
ADediting_71320	chr1_226605631_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-141-5p	chr1	226605626	226605633	8mer-1a	226605611	226605633	147	-15.96
ADediting_71322	chr1_226605634_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-1250-3p	chr1	226605627	226605634	8mer-1a	226605615	226605634	151	-13.51
ADediting_71324	chr1_226605651_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4643	chr1	226605647	226605653	7mer-m8	226605633	226605654	140	-10.52
ADediting_71324	chr1_226605651_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4717-3p	chr1	226605646	226605652	7mer-m8	226605633	226605653	159	-23.57

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

ADeditom_ID	Position	ENSG	ENST	Transcript name	miRNA ID	Chromosome	Targt	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
ADediting_71282	chr1_226604124_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-215-3p	chr1	226604118	226604124	7mer-m8	226604104	226604125	155	-19.62
ADediting_71282	chr1_226604124_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-215-3p	chr1	226604118	226604124	7mer-m8	226604104	226604125	155	-19.62
ADediting_71283	chr1_226604131_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-1200	chr1	226604127	226604133	7mer-m8	226604112	226604134	145	-22.71
ADediting_71283	chr1_226604131_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4324	chr1	226604126	226604133	8mer-1a	226604114	226604133	150	-17.81
ADediting_71283	chr1_226604131_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4329	chr1	226604125	226604131	7mer-m8	226604114	226604132	145	-21.03
ADediting_71283	chr1_226604131_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-544b	chr1	226604127	226604133	7mer-1a	226604112	226604133	145	-19.2
ADediting_71283	chr1_226604131_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-660-3p	chr1	226604129	226604135	7mer-m8	226604117	226604136	146	-15.99
ADediting_71283	chr1_226604131_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-1200	chr1	226604127	226604133	7mer-m8	226604112	226604134	145	-22.71
ADediting_71283	chr1_226604131_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4324	chr1	226604126	226604133	8mer-1a	226604114	226604133	150	-17.81
ADediting_71283	chr1_226604131_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4329	chr1	226604125	226604131	7mer-m8	226604114	226604132	145	-21.03
ADediting_71283	chr1_226604131_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-544b	chr1	226604127	226604133	7mer-1a	226604112	226604133	145	-19.2
ADediting_71283	chr1_226604131_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-660-3p	chr1	226604129	226604135	7mer-m8	226604117	226604136	146	-15.99
ADediting_71284	chr1_226604134_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-1200	chr1	226604127	226604133	7mer-m8	226604112	226604134	145	-22.71
ADediting_71284	chr1_226604134_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4667-3p	chr1	226604130	226604136	7mer-m8	226604113	226604137	154	-29.21
ADediting_71284	chr1_226604134_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-660-3p	chr1	226604129	226604135	7mer-m8	226604117	226604136	146	-15.99
ADediting_71284	chr1_226604134_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-6887-3p	chr1	226604131	226604137	7mer-m8	226604112	226604138	144	-21.45
ADediting_71284	chr1_226604134_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-1200	chr1	226604127	226604133	7mer-m8	226604112	226604134	145	-22.71
ADediting_71284	chr1_226604134_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4667-3p	chr1	226604130	226604136	7mer-m8	226604113	226604137	154	-29.21
ADediting_71284	chr1_226604134_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-660-3p	chr1	226604129	226604135	7mer-m8	226604117	226604136	146	-15.99
ADediting_71284	chr1_226604134_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-6887-3p	chr1	226604131	226604137	7mer-m8	226604112	226604138	144	-21.45
ADediting_71286	chr1_226604164_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-718	chr1	226604157	226604163	7mer-m8	226604145	226604164	145	-22.31
ADediting_71286	chr1_226604164_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-718	chr1	226604157	226604163	7mer-m8	226604145	226604164	145	-22.31
ADediting_71288	chr1_226604201_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4291	chr1	226604194	226604200	7mer-m8	226604186	226604201	140	-14.65
ADediting_71288	chr1_226604201_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4291	chr1	226604194	226604200	7mer-m8	226604186	226604201	140	-14.65
ADediting_71289	chr1_226604209_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4778-3p	chr1	226604207	226604214	8mer-1a	226604190	226604214	150	-24.88
ADediting_71289	chr1_226604209_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-6802-3p	chr1	226604202	226604209	8mer-1a	226604191	226604209	155	-26.05
ADediting_71289	chr1_226604209_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4778-3p	chr1	226604207	226604214	8mer-1a	226604190	226604214	150	-24.88
ADediting_71289	chr1_226604209_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-6802-3p	chr1	226604202	226604209	8mer-1a	226604191	226604209	155	-26.05
ADediting_71290	chr1_226604210_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4778-3p	chr1	226604207	226604214	8mer-1a	226604190	226604214	150	-24.88
ADediting_71290	chr1_226604210_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4778-3p	chr1	226604207	226604214	8mer-1a	226604190	226604214	150	-24.88
ADediting_71291	chr1_226604212_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4778-3p	chr1	226604207	226604214	8mer-1a	226604190	226604214	150	-24.88
ADediting_71291	chr1_226604212_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4778-3p	chr1	226604207	226604214	8mer-1a	226604190	226604214	150	-24.88
ADediting_71292	chr1_226604213_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4778-3p	chr1	226604207	226604214	8mer-1a	226604190	226604214	150	-24.88
ADediting_71292	chr1_226604213_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4778-3p	chr1	226604207	226604214	8mer-1a	226604190	226604214	150	-24.88
ADediting_71294	chr1_226604222_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-302f	chr1	226604218	226604224	7mer-m8	226604208	226604225	141	-7.18
ADediting_71294	chr1_226604222_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-302f	chr1	226604218	226604224	7mer-m8	226604208	226604225	141	-7.18
ADediting_71295	chr1_226604223_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-302f	chr1	226604218	226604224	7mer-m8	226604208	226604225	141	-7.18
ADediting_71295	chr1_226604223_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-302f	chr1	226604218	226604224	7mer-m8	226604208	226604225	141	-7.18
ADediting_71298	chr1_226604248_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-599	chr1	226604242	226604248	7mer-m8	226604231	226604249	151	-12.54
ADediting_71298	chr1_226604248_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-599	chr1	226604242	226604248	7mer-m8	226604231	226604249	151	-12.54
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-378j	chr1	226604247	226604254	8mer-1a	226604235	226604254	144	-12.19
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-599	chr1	226604242	226604248	7mer-m8	226604231	226604249	151	-12.54
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-6839-5p	chr1	226604247	226604254	8mer-1a	226604233	226604254	145	-17.22
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-378j	chr1	226604247	226604254	8mer-1a	226604235	226604254	144	-12.19
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-599	chr1	226604242	226604248	7mer-m8	226604231	226604249	151	-12.54
ADediting_71299	chr1_226604249_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-6839-5p	chr1	226604247	226604254	8mer-1a	226604233	226604254	145	-17.22
ADediting_71302	chr1_226605518_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4501	chr1	226605514	226605520	7mer-m8	226605501	226605521	142	-12.58
ADediting_71302	chr1_226605518_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4501	chr1	226605514	226605520	7mer-m8	226605501	226605521	142	-12.58
ADediting_71303	chr1_226605540_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4654	chr1	226605534	226605540	7mer-m8	226605521	226605541	143	-15.59
ADediting_71303	chr1_226605540_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4769-5p	chr1	226605534	226605540	7mer-m8	226605516	226605541	149	-21.23
ADediting_71303	chr1_226605540_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-5089-5p	chr1	226605533	226605539	7mer-m8	226605518	226605540	149	-16.44
ADediting_71303	chr1_226605540_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-552-3p	chr1	226605538	226605544	7mer-m8	226605522	226605545	142	-12.53
ADediting_71303	chr1_226605540_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4654	chr1	226605534	226605540	7mer-m8	226605521	226605541	143	-15.59
ADediting_71303	chr1_226605540_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4769-5p	chr1	226605534	226605540	7mer-m8	226605516	226605541	149	-21.23
ADediting_71303	chr1_226605540_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-5089-5p	chr1	226605533	226605539	7mer-m8	226605518	226605540	149	-16.44
ADediting_71303	chr1_226605540_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-552-3p	chr1	226605538	226605544	7mer-m8	226605522	226605545	142	-12.53
ADediting_71308	chr1_226605571_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4666b	chr1	226605564	226605571	8mer-1a	226605547	226605571	148	-15.34
ADediting_71308	chr1_226605571_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4666b	chr1	226605564	226605571	8mer-1a	226605547	226605571	148	-15.34
ADediting_71316	chr1_226605603_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-7160-5p	chr1	226605598	226605605	8mer-1a	226605585	226605605	140	-17.81
ADediting_71316	chr1_226605603_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-93-3p	chr1	226605600	226605606	7mer-m8	226605586	226605607	145	-14.09
ADediting_71317	chr1_226605606_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-6762-3p	chr1	226605602	226605608	7mer-m8	226605587	226605609	140	-16.85
ADediting_71317	chr1_226605606_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-93-3p	chr1	226605600	226605606	7mer-m8	226605586	226605607	145	-14.09
ADediting_71318	chr1_226605622_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4453	chr1	226605618	226605624	7mer-m8	226605605	226605625	149	-19.89
ADediting_71318	chr1_226605622_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4538	chr1	226605618	226605624	7mer-m8	226605603	226605625	151	-21.84
ADediting_71322	chr1_226605634_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-21-5p	chr1	226605631	226605637	7mer-m8	226605617	226605638	140	-10.69
ADediting_71322	chr1_226605634_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-590-5p	chr1	226605631	226605637	7mer-m8	226605617	226605638	145	-12.08
ADediting_71323	chr1_226605635_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-21-5p	chr1	226605631	226605637	7mer-m8	226605617	226605638	140	-10.69
ADediting_71323	chr1_226605635_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-590-5p	chr1	226605631	226605637	7mer-m8	226605617	226605638	145	-12.08
ADediting_71324	chr1_226605651_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-5580-3p	chr1	226605647	226605653	7mer-m8	226605633	226605654	153	-18.77

RNA A-to-I editing in lncRNA gained miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

ADeditom_ID	Position	ENSG	ENST	Transcript name	miRNA ID	Chromosome	Targt	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
ADediting_1097295	chr3_85385762_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-5688	chr1	226603547	226603553	7mer-m8	226603531	226603554	151	-14.39
ADediting_1097295	chr3_85385762_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-5688	chr1	226603547	226603553	7mer-m8	226603531	226603554	151	-14.39
ADediting_1337757	chr7_5495852_-	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-589-3p	chr1	226602237	226602243	7mer-m8	226602222	226602244	144	-20.38
ADediting_1337757	chr7_5495852_-	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-589-3p	chr1	226602237	226602243	7mer-m8	226602222	226602244	144	-20.38
ADediting_1337758	chr7_5495892_-	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-589-5p	chr1	226605182	226605189	8mer-1a	226605170	226605189	164	-28.38
ADediting_1337758	chr7_5495892_-	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-589-5p	chr1	226605182	226605189	8mer-1a	226605170	226605189	164	-28.38
ADediting_1391023	chr8_140732605_-	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-151a-3p	chr1	226607815	226607821	7mer-m8	226607801	226607822	150	-16.72
ADediting_1391023	chr8_140732605_-	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-151a-3p	chr1	226608685	226608691	7mer-m8	226608672	226608692	140	-18.23
ADediting_1471004	chr9_63819627_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4477b	chr1	226603305	226603311	7mer-m8	226603293	226603312	141	-14.43
ADediting_1471004	chr9_63819627_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4477b	chr1	226603305	226603311	7mer-m8	226603293	226603312	141	-14.43
ADediting_496066	chr15_66496985_-	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4512	chr1	226604422	226604428	7mer-m8	226604409	226604429	146	-22.86
ADediting_496066	chr15_66496985_-	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4512	chr1	226604462	226604468	7mer-m8	226604448	226604469	156	-25.29
ADediting_496066	chr15_66496985_-	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-4512	chr1	226608810	226608816	7mer-1a	226608793	226608816	142	-24.02
ADediting_496066	chr15_66496985_-	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4512	chr1	226604422	226604428	7mer-m8	226604409	226604429	146	-22.86
ADediting_496066	chr15_66496985_-	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-4512	chr1	226604462	226604468	7mer-m8	226604448	226604469	156	-25.29
ADediting_98288	chr1_32086990_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-5585-3p	chr1	226604007	226604013	7mer-m8	226603991	226604014	153	-24.14
ADediting_98288	chr1_32086990_+	ENSG00000203685.10	ENST00000366789.5	STUM-202	hsa-miR-5585-3p	chr1	226604007	226604013	7mer-m8	226603991	226604014	153	-24.14
ADediting_98289	chr1_32086992_+	ENSG00000203685.10	ENST00000366788.8	STUM-201	hsa-miR-5585-3p	chr1	226608262	226608268	7mer-m8	226608248	226608269	140	-10.87

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_107020

chr1_37500952_-

ENSG00000203685.10

ENST00000366788.8

STUM-201

hsa-miR-5581-3p

chr1

226607258

226607264

7mer-m8

226607245

226607265

154

-22.9

ADediting_1337758

chr7_5495892_-

ENSG00000203685.10

ENST00000366788.8

STUM-201

hsa-miR-589-5p

chr1

226604679

226604685

7mer-m8

226604665

226604686

140

-16.97

ADediting_1337758

chr7_5495892_-

ENSG00000203685.10

ENST00000366789.5

STUM-202

hsa-miR-589-5p

chr1

226604679

226604685

7mer-m8

226604665

226604686

140

-16.97

ADediting_1391023

chr8_140732605_-

ENSG00000203685.10

ENST00000366788.8

STUM-201

hsa-miR-151a-3p

chr1

226603069

226603076

8mer-1a

226603057

226603076

151

-20.16

ADediting_1391023

chr8_140732605_-

ENSG00000203685.10

ENST00000366789.5

STUM-202

hsa-miR-151a-3p

chr1

226603069

226603076

8mer-1a

226603057

226603076

151

-20.16

ADediting_496066

chr15_66496985_-

ENSG00000203685.10

ENST00000366788.8

STUM-201

hsa-miR-4512

chr1

226607305

226607311

7mer-m8

226607291

226607312

140

-16.79

ADediting_843620

chr2_207754818_+

ENSG00000203685.10

ENST00000366788.8

STUM-201

hsa-miR-4775

chr1

226603379

226603385

7mer-1a

226603371

226603395

140

-12.01

ADediting_843620

chr2_207754818_+

ENSG00000203685.10

ENST00000366788.8

STUM-201

hsa-miR-4775

chr1

226604671

226604677

7mer-m8

226604657

226604678

149

-8.78

ADediting_843620

chr2_207754818_+

ENSG00000203685.10

ENST00000366789.5

STUM-202

hsa-miR-4775

chr1

226603379

226603385

7mer-1a

226603371

226603395

140

-12.01

ADediting_843620

chr2_207754818_+

ENSG00000203685.10

ENST00000366789.5

STUM-202

hsa-miR-4775

chr1

226604671

226604677

7mer-m8

226604657

226604678

149

-8.78

Differentially expressed gene-miRNA network

Differentially expressed mRNA-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for STUM

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000366788.8	protein_coding
ENST00000366789.5	protein_coding

RNA A-to-I editing in miRNA.

ADeditom_ID

ENST

mir_ID

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

RNA A-to-I editing in mRNA.

ADeditom_ID	ENST	Editing_Information	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
ADediting_71282	ENST00000366788.8	chr1_226604124_+	2651	-3210.90	-3211.60	-3217.90
ADediting_71283	ENST00000366788.8	chr1_226604131_+	2658	-3210.90	-3211.60	-3217.90
ADediting_71284	ENST00000366788.8	chr1_226604134_+	2661	-3210.70	-3211.60	-3217.90
ADediting_71285	ENST00000366788.8	chr1_226604151_+	2678	-3211.60	-3211.60	-3217.90
ADediting_71286	ENST00000366788.8	chr1_226604164_+	2691	-3211.30	-3211.60	-3217.90
ADediting_71287	ENST00000366788.8	chr1_226604169_+	2696	-3211.60	-3211.60	-3217.90
ADediting_71288	ENST00000366788.8	chr1_226604201_+	2728	-3210.70	-3211.60	-3217.90
ADediting_71289	ENST00000366788.8	chr1_226604209_+	2736	-3218.50	-3211.60	-3217.90
ADediting_71290	ENST00000366788.8	chr1_226604210_+	2737	-3211.60	-3211.60	-3217.90
ADediting_71291	ENST00000366788.8	chr1_226604212_+	2739	-3211.10	-3211.60	-3217.90
ADediting_71292	ENST00000366788.8	chr1_226604213_+	2740	-3211.30	-3211.60	-3217.90
ADediting_71293	ENST00000366788.8	chr1_226604219_+	2746	-3218.20	-3211.60	-3217.90
ADediting_71294	ENST00000366788.8	chr1_226604222_+	2749	-3212.00	-3211.60	-3217.90
ADediting_71295	ENST00000366788.8	chr1_226604223_+	2750	-3211.60	-3211.60	-3217.90
ADediting_71296	ENST00000366788.8	chr1_226604227_+	2754	-3211.60	-3211.60	-3217.90
ADediting_71297	ENST00000366788.8	chr1_226604240_+	2767	-3211.30	-3211.60	-3217.90
ADediting_71298	ENST00000366788.8	chr1_226604248_+	2775	-3211.30	-3211.60	-3217.90
ADediting_71299	ENST00000366788.8	chr1_226604249_+	2776	-3211.60	-3211.60	-3217.90
ADediting_71300	ENST00000366788.8	chr1_226604906_+	3433	-3215.00	-3211.60	-3217.90
ADediting_71301	ENST00000366788.8	chr1_226605513_+	4040	-3213.50	-3211.60	-3217.90
ADediting_71302	ENST00000366788.8	chr1_226605518_+	4045	-3211.20	-3211.60	-3217.90
ADediting_71303	ENST00000366788.8	chr1_226605540_+	4067	-3211.20	-3211.60	-3217.90
ADediting_71304	ENST00000366788.8	chr1_226605560_+	4087	-3211.20	-3211.60	-3217.90
ADediting_71305	ENST00000366788.8	chr1_226605563_+	4090	-3211.70	-3211.60	-3217.90
ADediting_71306	ENST00000366788.8	chr1_226605564_+	4091	-3211.70	-3211.60	-3217.90
ADediting_71307	ENST00000366788.8	chr1_226605565_+	4092	-3211.60	-3211.60	-3217.90
ADediting_71308	ENST00000366788.8	chr1_226605571_+	4098	-3217.60	-3211.60	-3217.90
ADediting_71309	ENST00000366788.8	chr1_226605572_+	4099	-3211.80	-3211.60	-3217.90
ADediting_71310	ENST00000366788.8	chr1_226605574_+	4101	-3211.20	-3211.60	-3217.90
ADediting_71311	ENST00000366788.8	chr1_226605576_+	4103	-3211.70	-3211.60	-3217.90
ADediting_71312	ENST00000366788.8	chr1_226605577_+	4104	-3211.70	-3211.60	-3217.90
ADediting_71313	ENST00000366788.8	chr1_226605578_+	4105	-3211.60	-3211.60	-3217.90
ADediting_71314	ENST00000366788.8	chr1_226605581_+	4108	-3218.30	-3211.60	-3217.90
ADediting_71315	ENST00000366788.8	chr1_226605584_+	4111	-3211.90	-3211.60	-3217.90
ADediting_71316	ENST00000366788.8	chr1_226605603_+	4130	-3210.90	-3211.60	-3217.90
ADediting_71317	ENST00000366788.8	chr1_226605606_+	4133	-3210.90	-3211.60	-3217.90
ADediting_71318	ENST00000366788.8	chr1_226605622_+	4149	-3211.30	-3211.60	-3217.90
ADediting_71319	ENST00000366788.8	chr1_226605630_+	4157	-3211.70	-3211.60	-3217.90
ADediting_71320	ENST00000366788.8	chr1_226605631_+	4158	-3211.70	-3211.60	-3217.90
ADediting_71321	ENST00000366788.8	chr1_226605632_+	4159	-3211.60	-3211.60	-3217.90
ADediting_71322	ENST00000366788.8	chr1_226605634_+	4161	-3211.70	-3211.60	-3217.90
ADediting_71323	ENST00000366788.8	chr1_226605635_+	4162	-3211.30	-3211.60	-3217.90
ADediting_71324	ENST00000366788.8	chr1_226605651_+	4178	-3211.60	-3211.60	-3217.90
ADediting_71325	ENST00000366788.8	chr1_226605682_+	4209	-3211.20	-3211.60	-3217.90
ADediting_71326	ENST00000366788.8	chr1_226605685_+	4212	-3211.20	-3211.60	-3217.90
ADediting_71282	ENST00000366789.5	chr1_226604124_+	2615	-1687.70	-1686.50	-1711.30
ADediting_71283	ENST00000366789.5	chr1_226604131_+	2622	-1688.20	-1686.50	-1711.30
ADediting_71284	ENST00000366789.5	chr1_226604134_+	2625	-1690.50	-1686.50	-1711.30
ADediting_71285	ENST00000366789.5	chr1_226604151_+	2642	-1686.50	-1686.50	-1711.30
ADediting_71286	ENST00000366789.5	chr1_226604164_+	2655	-1688.10	-1686.50	-1711.30
ADediting_71287	ENST00000366789.5	chr1_226604169_+	2660	-1686.50	-1686.50	-1711.30
ADediting_71288	ENST00000366789.5	chr1_226604201_+	2692	-1685.60	-1686.50	-1711.30
ADediting_71289	ENST00000366789.5	chr1_226604209_+	2700	-1693.40	-1686.50	-1711.30
ADediting_71290	ENST00000366789.5	chr1_226604210_+	2701	-1686.50	-1686.50	-1711.30
ADediting_71291	ENST00000366789.5	chr1_226604212_+	2703	-1686.00	-1686.50	-1711.30
ADediting_71292	ENST00000366789.5	chr1_226604213_+	2704	-1686.20	-1686.50	-1711.30
ADediting_71293	ENST00000366789.5	chr1_226604219_+	2710	-1693.10	-1686.50	-1711.30
ADediting_71294	ENST00000366789.5	chr1_226604222_+	2713	-1686.90	-1686.50	-1711.30
ADediting_71295	ENST00000366789.5	chr1_226604223_+	2714	-1686.50	-1686.50	-1711.30
ADediting_71296	ENST00000366789.5	chr1_226604227_+	2718	-1686.50	-1686.50	-1711.30
ADediting_71297	ENST00000366789.5	chr1_226604240_+	2731	-1686.20	-1686.50	-1711.30
ADediting_71298	ENST00000366789.5	chr1_226604248_+	2739	-1686.20	-1686.50	-1711.30
ADediting_71299	ENST00000366789.5	chr1_226604249_+	2740	-1686.50	-1686.50	-1711.30
ADediting_71300	ENST00000366789.5	chr1_226604906_+	3397	-1689.90	-1686.50	-1711.30
ADediting_71301	ENST00000366789.5	chr1_226605513_+	4004	-1688.40	-1686.50	-1711.30
ADediting_71302	ENST00000366789.5	chr1_226605518_+	4009	-1686.10	-1686.50	-1711.30
ADediting_71303	ENST00000366789.5	chr1_226605540_+	4031	-1686.10	-1686.50	-1711.30
ADediting_71304	ENST00000366789.5	chr1_226605560_+	4051	-1686.10	-1686.50	-1711.30
ADediting_71305	ENST00000366789.5	chr1_226605563_+	4054	-1686.60	-1686.50	-1711.30
ADediting_71306	ENST00000366789.5	chr1_226605564_+	4055	-1686.60	-1686.50	-1711.30
ADediting_71307	ENST00000366789.5	chr1_226605565_+	4056	-1686.50	-1686.50	-1711.30
ADediting_71308	ENST00000366789.5	chr1_226605571_+	4062	-1692.50	-1686.50	-1711.30
ADediting_71309	ENST00000366789.5	chr1_226605572_+	4063	-1686.70	-1686.50	-1711.30
ADediting_71310	ENST00000366789.5	chr1_226605574_+	4065	-1686.10	-1686.50	-1711.30
ADediting_71311	ENST00000366789.5	chr1_226605576_+	4067	-1686.60	-1686.50	-1711.30
ADediting_71312	ENST00000366789.5	chr1_226605577_+	4068	-1686.60	-1686.50	-1711.30
ADediting_71313	ENST00000366789.5	chr1_226605578_+	4069	-1686.50	-1686.50	-1711.30
ADediting_71314	ENST00000366789.5	chr1_226605581_+	4072	-1693.20	-1686.50	-1711.30
ADediting_71315	ENST00000366789.5	chr1_226605584_+	4075	-1686.80	-1686.50	-1711.30

RNA A-to-I editing in lncRNA.

ADeditom_ID

ENST

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

Top

Relation with ADAR for STUM

Correlation between ADAR gene expression and RNA editing frequency

Tissue	ADeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
DLPFC	ADediting_71283	chr1_226604131_+	1.27415347501523e-08	0.316095816768663	1.70358418296864e-05	0.241603956526493	4.01944392450748e-06	0.258433975912251
DLPFC	ADediting_71284	chr1_226604134_+	5.44973999394577e-09	0.323631683661281	5.51972910584929e-06	0.254837695873026	0.000546314501927338	0.195237828643138
DLPFC	ADediting_71287	chr1_226604169_+	1.47270170298703e-08	0.314789768520471	1.97354426914323e-05	0.239820535744293	0.000754297016140343	0.19036507802668
CER	ADediting_71288	chr1_226604201_+	3.60480817672519e-05	0.330564018760126	0.01260229635994	0.203269915351678	0.0480271945063722	0.161720407006331
TCX	ADediting_71288	chr1_226604201_+	1.87908593293814e-05	0.34164887568134	0.000972019661799198	0.266658676329286	0.915230608097154	0.00876421233146763
TCX	ADediting_71289	chr1_226604209_+	0.000166478902397728	0.30270738904804	0.0110869910061755	0.206867846648367	0.747439426337761	0.0265097643823264
IFG	ADediting_71289	chr1_226604209_+	0.0256202109349872	0.445518351433814	0.265933095397787	0.231303148143534	0.97360581581069	-0.00697424664773262
TCX	ADediting_71290	chr1_226604210_+	0.000202276359137316	0.298954651832618	9.20542664803774e-05	0.313822493124029	0.0270977042199432	-0.180479792247785
DLPFC	ADediting_71292	chr1_226604213_+	8.10465702297406e-11	0.358224466532556	6.14350033868666e-08	0.301556970129156	0.519141414986595	0.0367508578842699
TCX	ADediting_71292	chr1_226604213_+	3.01959692128287e-05	0.333620341463312	0.000546664906454656	0.278954704942109	0.837565021702529	-0.0168789299292401
DLPFC	ADediting_71293	chr1_226604219_+	4.1688148427035e-15	0.426122109266983	4.33093237867595e-08	0.304857078019257	0.0484722569236039	0.112169711952182
CER	ADediting_71293	chr1_226604219_+	1.68153381452503e-06	0.379421235454194	0.00086845106434829	0.269111102810414	0.00298830935981339	0.240848696253341
TCX	ADediting_71293	chr1_226604219_+	6.86571667717537e-05	0.319165662614188	0.0405213123238025	0.167468634710681	0.638523235521438	0.0386652198140447
DLPFC	ADediting_71294	chr1_226604222_+	3.60303987375206e-11	0.364429520357545	5.60647111338696e-06	0.254659516920324	0.134218976999663	0.0852514184276093
CER	ADediting_71295	chr1_226604223_+	0.000176522741159611	0.301583985188491	0.00475610055719777	0.229343473104267	0.0173425881017781	0.194047119500512
DLPFC	ADediting_71296	chr1_226604227_+	1.66945511115552e-16	0.445287814681888	6.44521044680955e-11	0.359991692439405	0.0969012865151639	0.0944560525104258
CER	ADediting_71296	chr1_226604227_+	2.67842431688705e-09	0.461934220133513	1.04820651387143e-05	0.351234705861023	0.00140548117856696	0.25846687606935
IFG	ADediting_71296	chr1_226604227_+	0.251702447189365	0.238119232454287	0.467384218575043	0.152294055009753	0.0317371037681554	0.430410774201658
DLPFC	ADediting_71297	chr1_226604240_+	5.98549554781987e-19	0.476171374739486	5.56865448672814e-13	0.394409505509447	0.122238761360997	0.0879604826237649
CER	ADediting_71297	chr1_226604240_+	0.000109631313187492	0.310589848464359	0.000773599017516332	0.271605143893	0.00313543526448124	0.23968337582771
IFG	ADediting_71297	chr1_226604240_+	0.242322501766778	0.242750011770612	0.243060313764203	0.242381555821878	0.0143479951722994	0.483471227014455
TCX	ADediting_71303	chr1_226605540_+	0.154223275011668	0.116910787227892	0.617195453004651	-0.041137724252216	0.000146110190994675	0.30519392010824
DLPFC	ADediting_71308	chr1_226605571_+	6.58881853997025e-11	0.359822178873329	1.97249152992845e-06	0.26631696456194	0.0512781741985105	0.11081046491485
IFG	ADediting_71308	chr1_226605571_+	0.0140905635447745	0.484592938458957	0.0327076936948424	0.428233210330793	0.500376462540565	-0.141336332132824
DLPFC	ADediting_71311	chr1_226605576_+	3.70078222198169e-10	0.346224933166678	5.31168527528058e-07	0.280221235082719	0.0442308286204688	0.114354911338959
DLPFC	ADediting_71312	chr1_226605577_+	4.03522856438637e-15	0.426322302100862	4.71401934480929e-10	0.344265143792428	0.00653482344133106	0.154164849505036
TCX	ADediting_71312	chr1_226605577_+	6.37259792240641e-06	0.359167947285302	0.000310491897637077	0.290513603271634	0.769005519049669	0.0241772908686924
DLPFC	ADediting_71314	chr1_226605581_+	2.06339565838765e-17	0.457122796057124	4.27884490420703e-12	0.380131561193835	0.0650362612928572	0.104923907363017
TCX	ADediting_71314	chr1_226605581_+	3.7410927193384e-07	0.400746015226203	5.47033675910703e-06	0.361559653085853	0.662253127179383	-0.0359541767210887
DLPFC	ADediting_71315	chr1_226605584_+	3.60090274265192e-13	0.397374714281504	2.58812957227932e-09	0.330072648045663	0.0210597253403135	0.130987945275769
TCX	ADediting_71315	chr1_226605584_+	6.99771521830206e-05	0.318821728483258	0.00113029980298491	0.263338435342302	0.440104962857351	-0.0635024114810688
DLPFC	ADediting_71317	chr1_226605606_+	6.19297435032142e-13	0.393682258075825	5.58880386237622e-07	0.279696307027609	0.0194100892656222	0.132712834205646
TCX	ADediting_71317	chr1_226605606_+	8.08266533142535e-06	0.355405051817508	6.84177844094915e-05	0.319228698413218	0.277560999997487	-0.0892258490069867
DLPFC	ADediting_71319	chr1_226605630_+	3.89506576613682e-05	0.231393974307088	0.0619422448807728	0.106151034559009	1.78112309720469e-09	0.333249350232445
TCX	ADediting_71322	chr1_226605634_+	0.00037083680711223	0.286937353089433	1.20586196528298e-05	0.348962103347523	0.0038288304761772	-0.234779489160295
TCX	ADediting_71323	chr1_226605635_+	0.00287356643959357	0.24179405526962	0.000105909412601918	0.311231742438303	0.00134820800577758	-0.259404109592541

Correlation between ADAR gene expression and this gene's expression

Tissue	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
DLPFC	5.92190047888931e-49	0.710638936723085	1.40647407615755e-52	0.728726360995282	0.241570091671175	0.0667077575623913
AC	8.46185272471677e-75	0.861065693146626	4.96798598487279e-85	0.886636281649045	0.00777386580814188	0.167986913832183
PCC	6.81170978494954e-31	0.712452098936462	2.77838644781944e-20	0.602834959667873	0.313788898035264	0.0732688747604276
CER	2.6930080737677e-09	0.461873170767037	0.000243492114661141	0.29533344597863	0.000183945950453414	0.30079131382519
TCX	6.32211056114815e-11	0.501427265774117	1.85711404256395e-13	0.554298531649989	0.00030812393125004	-0.290666709054867
FP	5.26371933954239e-15	0.542423370983889	2.10225969613821e-07	0.377202294696903	0.000801456755415372	0.249048475376865
IFG	0.000492836439065025	0.64549953562967	0.00193793218264029	0.589275997306664	0.875834678560333	0.0329277116067402
PG	3.73385842266079e-09	0.41539156892137	5.48610020936531e-08	0.385580071037562	0.712146709440821	0.0272330926601849
STG	6.02998050082983e-06	0.471338933194637	0.000153508369969942	0.401507569300931	0.407757103891028	0.0915069268171731

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Relation with AD stages for STUM

Correlation between AD stages and RNA editing frequency

Tissue	ADeditomID	position	P-val	Coeff.
TCX	ADediting_71317	chr1_226605606_+	0.00156614590436284	0.303455861076133

Correlation between AD stages and this gene's expression

Tissue	P-val	Coeff.
CER	0.000103821306718588	0.364785419041677

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RelatedDrugs for STUM

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for STUM

Diseases associated with this gene.
(DisGeNet 4.0)

Gene

Disease ID

Disease name

# pubmeds

Source

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Gene summary for STUM

RNA A-to-I events for STUM

RNA editing positional annotations for STUM using Annovar

RNA A-to-I editing events in the alternative splicing sites for STUM

Differntial gene expression between RNA A-to-I edited versus non-edited samples for STUM

Protein coding region RNA A-to-I editings for STUM

The effects of the RNA editing to the miRNA binding sites for STUM

The effects of the RNA editing to the stability of the RNA structures for STUM

Relation with ADAR for STUM

Relation with AD stages for STUM

RelatedDrugs for STUM

RelatedDiseases for STUM

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited versus non-edited samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with AD stages
	Related drugs with this gene
	Related diseases with this gene