ADeditome: functional annotation of RNA A-to-I editing in AD

Gene summary for ACADM

Gene summary

Gene information	Gene symbol	ACADM
	Gene ID	34
	Gene name	acyl-CoA dehydrogenase medium chain
	Synonyms	ACAD1\|MCAD\|MCADH
	Cytomap	1p31.1
	Type of gene	protein-coding
	Description	medium-chain specific acyl-CoA dehydrogenase, mitochondrialacyl-CoA dehydrogenase, C-4 to C-12 straight chainacyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chainmedium-chain acyl-CoA dehydrogenasetesticular tissue protein Li 7
	Modification date	20200313
	UniProtAcc	P11310,
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
ACADM	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	1902818\|3597357\|19224950\|25416781
ACADM	GO:0051791	medium-chain fatty acid metabolic process	1970566
ACADM	GO:0051793	medium-chain fatty acid catabolic process	1970566
ACADM	GO:0055114	oxidation-reduction process	1902818

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RNA A-to-I events for ACADM

RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA editing frequencies across three data sets.

The number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA A-to-I editing events in AD.

ADediting_138857(75726232, +), ADediting_138858(75726247, +), ADediting_138859(75726248, +), ADediting_138860(75726249, +), ADediting_138861(75726250, +), ADediting_138862(75726252, +), ADediting_138863(75726258, +), ADediting_138864(75726259, +), ADediting_138865(75726262, +), ADediting_138866(75726270, +), ADediting_138867(75726275, +), ADediting_138868(75726289, +), ADediting_138869(75726294, +), ADediting_138870(75726856, +), ADediting_138871(75726860, +), ADediting_138872(75726885, +), ADediting_138873(75726962, +), ADediting_138874(75726971, +), ADediting_138875(75726988, +), ADediting_138876(75727025, +), ADediting_138877(75727050, +), ADediting_138878(75727065, +), ADediting_138879(75729523, +), ADediting_138880(75729574, +), ADediting_138881(75729666, +), ADediting_138882(75729953, +), ADediting_138883(75729975, +), ADediting_138884(75729994, +), ADediting_138885(75729995, +), ADediting_138886(75730012, +), ADediting_138887(75730020, +), ADediting_138888(75730021, +), ADediting_138889(75730029, +), ADediting_138890(75730034, +), ADediting_138891(75730036, +), ADediting_138892(75730060, +), ADediting_138893(75730067, +), ADediting_138894(75730069, +), ADediting_138895(75730075, +), ADediting_138896(75730078, +), ADediting_138897(75730117, +), ADediting_138898(75730130, +), ADediting_138899(75730138, +), ADediting_138900(75730558, +), ADediting_138901(75730559, +), ADediting_138902(75730561, +), ADediting_138903(75730565, +), ADediting_138904(75730573, +), ADediting_138905(75730581, +), ADediting_138906(75730634, +), ADediting_138907(75730650, +), ADediting_138908(75730655, +), ADediting_138909(75730673, +), ADediting_138910(75730679, +), ADediting_138911(75730729, +), ADediting_138912(75730779, +), ADediting_138913(75730789, +), ADediting_138914(75730790, +), ADediting_138915(75730795, +), ADediting_138916(75730879, +), ADediting_138917(75731032, +), ADediting_138918(75731037, +), ADediting_138919(75731132, +), ADediting_138920(75731158, +), ADediting_138921(75731164, +), ADediting_138922(75731172, +), ADediting_138923(75731181, +), ADediting_138924(75731183, +), ADediting_138925(75731185, +), ADediting_138926(75731747, +), ADediting_138927(75731783, +), ADediting_138928(75731796, +), ADediting_138929(75731823, +), ADediting_138930(75731824, +), ADediting_138931(75731842, +), ADediting_138932(75731918, +), ADediting_138933(75731919, +), ADediting_138934(75731951, +), ADediting_138935(75731968, +), ADediting_138936(75731973, +), ADediting_138937(75731987, +), ADediting_138938(75731991, +), ADediting_138939(75731992, +), ADediting_138940(75731999, +), ADediting_138941(75732005, +), ADediting_138942(75732037, +), ADediting_138943(75732041, +), ADediting_138944(75732049, +), ADediting_138945(75732062, +), ADediting_138946(75732067, +), ADediting_138947(75732071, +), ADediting_138948(75732072, +), ADediting_138949(75732091, +), ADediting_138950(75732135, +), ADediting_138951(75732137, +), ADediting_138952(75734044, +), ADediting_138953(75735145, +), ADediting_138954(75735193, +), ADediting_138955(75735195, +), ADediting_138956(75735196, +), ADediting_138957(75735209, +), ADediting_138958(75735251, +), ADediting_138959(75735271, +), ADediting_138960(75735643, +), ADediting_138961(75735756, +), ADediting_138962(75735894, +), ADediting_138963(75737195, +), ADediting_138964(75738010, +), ADediting_138965(75738034, +), ADediting_138966(75738042, +), ADediting_138967(75738108, +), ADediting_138968(75738190, +), ADediting_138969(75738317, +), ADediting_138970(75738411, +), ADediting_138971(75738450, +), ADediting_138972(75738456, +), ADediting_138973(75745278, +), ADediting_138974(75747566, +), ADediting_138975(75747572, +), ADediting_138976(75750797, +), ADediting_138977(75750812, +), ADediting_138978(75750813, +), ADediting_138979(75750826, +), ADediting_138980(75750843, +), ADediting_138981(75750878, +), ADediting_138982(75750888, +), ADediting_138983(75750890, +), ADediting_138984(75750914, +), ADediting_138985(75750929, +), ADediting_138986(75750932, +), ADediting_138987(75750934, +), ADediting_138988(75751011, +), ADediting_138989(75751086, +), ADediting_138990(75751087, +), ADediting_138991(75751092, +), ADediting_138992(75751265, +), ADediting_138993(75751523, +), ADediting_138994(75751543, +), ADediting_138995(75751552, +), ADediting_138996(75751560, +), ADediting_138997(75751660, +), ADediting_138998(75751767, +), ADediting_138999(75758260, +), ADediting_139000(75759739, +), ADediting_139001(75759742, +), ADediting_139002(75759748, +), ADediting_139003(75759762, +), ADediting_139004(75759801, +), ADediting_139005(75759841, +), ADediting_139006(75759883, +), ADediting_139007(75759895, +), ADediting_139008(75759935, +), ADediting_139009(75759943, +), ADediting_139010(75760016, +), ADediting_139011(75760100, +), ADediting_139012(75760165, +), ADediting_139013(75760166, +), ADediting_139014(75760211, +), ADediting_139015(75760233, +), ADediting_139016(75760243, +), ADediting_139017(75760311, +), ADediting_139018(75760328, +), ADediting_139019(75760332, +), ADediting_139020(75760333, +), ADediting_139021(75760334, +), ADediting_139022(75760354, +), ADediting_139023(75760363, +), ADediting_139024(75760367, +), ADediting_139025(75760375, +), ADediting_139026(75760403, +), ADediting_139027(75760404, +), ADediting_139028(75760412, +), ADediting_139029(75760486, +), ADediting_139030(75760935, +), ADediting_139031(75760951, +), ADediting_139032(75760952, +), ADediting_139033(75760966, +), ADediting_139034(75760974, +), ADediting_139035(75760975, +), ADediting_139036(75760978, +), ADediting_139037(75761028, +), ADediting_1521478(75726193, +), ADediting_1521479(75726198, +), ADediting_1521480(75726243, +), ADediting_1521481(75726861, +), ADediting_1521482(75750875, +), ADediting_1521483(75760528, +), ADediting_1602384(75730061, +), ADediting_1602385(75730129, +), ADediting_1602386(75746732, +), ADediting_1602387(75746748, +), ADediting_1602388(75746764, +),

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RNA editing positional annotations for ACADM using Annovar

Protein coding RNA editing(s).

ADeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

ADeditome ID	Position	Variant type
ADediting_138857	chr1_75726232_+	intronic
ADediting_138858	chr1_75726247_+	intronic
ADediting_138859	chr1_75726248_+	intronic
ADediting_138860	chr1_75726249_+	intronic
ADediting_138861	chr1_75726250_+	intronic
ADediting_138862	chr1_75726252_+	intronic
ADediting_138863	chr1_75726258_+	intronic
ADediting_138864	chr1_75726259_+	intronic
ADediting_138865	chr1_75726262_+	intronic
ADediting_138866	chr1_75726270_+	intronic
ADediting_138867	chr1_75726275_+	intronic
ADediting_138868	chr1_75726289_+	intronic
ADediting_138869	chr1_75726294_+	intronic
ADediting_138870	chr1_75726856_+	intronic
ADediting_138871	chr1_75726860_+	intronic
ADediting_138872	chr1_75726885_+	intronic
ADediting_138873	chr1_75726962_+	intronic
ADediting_138874	chr1_75726971_+	intronic
ADediting_138875	chr1_75726988_+	intronic
ADediting_138876	chr1_75727025_+	intronic
ADediting_138877	chr1_75727050_+	intronic
ADediting_138878	chr1_75727065_+	intronic
ADediting_138879	chr1_75729523_+	intronic
ADediting_138880	chr1_75729574_+	intronic
ADediting_138881	chr1_75729666_+	intronic
ADediting_138882	chr1_75729953_+	intronic
ADediting_138883	chr1_75729975_+	intronic
ADediting_138884	chr1_75729994_+	intronic
ADediting_138885	chr1_75729995_+	intronic
ADediting_138886	chr1_75730012_+	intronic
ADediting_138887	chr1_75730020_+	intronic
ADediting_138888	chr1_75730021_+	intronic
ADediting_138889	chr1_75730029_+	intronic
ADediting_138890	chr1_75730034_+	intronic
ADediting_138891	chr1_75730036_+	intronic
ADediting_138892	chr1_75730060_+	intronic
ADediting_138893	chr1_75730067_+	intronic
ADediting_138894	chr1_75730069_+	intronic
ADediting_138895	chr1_75730075_+	intronic
ADediting_138896	chr1_75730078_+	intronic
ADediting_138897	chr1_75730117_+	intronic
ADediting_138898	chr1_75730130_+	intronic
ADediting_138899	chr1_75730138_+	intronic
ADediting_138900	chr1_75730558_+	intronic
ADediting_138901	chr1_75730559_+	intronic
ADediting_138902	chr1_75730561_+	intronic
ADediting_138903	chr1_75730565_+	intronic
ADediting_138904	chr1_75730573_+	intronic
ADediting_138905	chr1_75730581_+	intronic
ADediting_138906	chr1_75730634_+	intronic
ADediting_138907	chr1_75730650_+	intronic
ADediting_138908	chr1_75730655_+	intronic
ADediting_138909	chr1_75730673_+	intronic
ADediting_138910	chr1_75730679_+	intronic
ADediting_138911	chr1_75730729_+	intronic
ADediting_138912	chr1_75730779_+	intronic
ADediting_138913	chr1_75730789_+	intronic
ADediting_138914	chr1_75730790_+	intronic
ADediting_138915	chr1_75730795_+	intronic
ADediting_138916	chr1_75730879_+	intronic
ADediting_138917	chr1_75731032_+	intronic
ADediting_138918	chr1_75731037_+	intronic
ADediting_138919	chr1_75731132_+	intronic
ADediting_138920	chr1_75731158_+	intronic
ADediting_138921	chr1_75731164_+	intronic
ADediting_138922	chr1_75731172_+	intronic
ADediting_138923	chr1_75731181_+	intronic
ADediting_138924	chr1_75731183_+	intronic
ADediting_138925	chr1_75731185_+	intronic
ADediting_138926	chr1_75731747_+	intronic
ADediting_138927	chr1_75731783_+	intronic
ADediting_138928	chr1_75731796_+	intronic
ADediting_138929	chr1_75731823_+	intronic
ADediting_138930	chr1_75731824_+	intronic
ADediting_138931	chr1_75731842_+	intronic
ADediting_138932	chr1_75731918_+	intronic
ADediting_138933	chr1_75731919_+	intronic
ADediting_138934	chr1_75731951_+	intronic
ADediting_138935	chr1_75731968_+	intronic
ADediting_138936	chr1_75731973_+	intronic
ADediting_138937	chr1_75731987_+	intronic
ADediting_138938	chr1_75731991_+	intronic
ADediting_138939	chr1_75731992_+	intronic
ADediting_138940	chr1_75731999_+	intronic
ADediting_138941	chr1_75732005_+	intronic
ADediting_138942	chr1_75732037_+	intronic
ADediting_138943	chr1_75732041_+	intronic
ADediting_138944	chr1_75732049_+	intronic
ADediting_138945	chr1_75732062_+	intronic
ADediting_138946	chr1_75732067_+	intronic
ADediting_138947	chr1_75732071_+	intronic
ADediting_138948	chr1_75732072_+	intronic
ADediting_138949	chr1_75732091_+	intronic
ADediting_138950	chr1_75732135_+	intronic
ADediting_138951	chr1_75732137_+	intronic
ADediting_138952	chr1_75734044_+	intronic
ADediting_138953	chr1_75735145_+	intronic
ADediting_138954	chr1_75735193_+	intronic
ADediting_138955	chr1_75735195_+	intronic
ADediting_138956	chr1_75735196_+	intronic
ADediting_138957	chr1_75735209_+	intronic
ADediting_138958	chr1_75735251_+	intronic
ADediting_138959	chr1_75735271_+	intronic
ADediting_138960	chr1_75735643_+	intronic
ADediting_138961	chr1_75735756_+	intronic
ADediting_138962	chr1_75735894_+	intronic
ADediting_138963	chr1_75737195_+	intronic
ADediting_138964	chr1_75738010_+	intronic
ADediting_138965	chr1_75738034_+	intronic
ADediting_138966	chr1_75738042_+	intronic
ADediting_138967	chr1_75738108_+	intronic
ADediting_138968	chr1_75738190_+	intronic
ADediting_138969	chr1_75738317_+	intronic
ADediting_138970	chr1_75738411_+	intronic
ADediting_138971	chr1_75738450_+	intronic
ADediting_138972	chr1_75738456_+	intronic
ADediting_138973	chr1_75745278_+	intronic
ADediting_138974	chr1_75747566_+	intronic
ADediting_138975	chr1_75747572_+	intronic
ADediting_138976	chr1_75750797_+	intronic
ADediting_138977	chr1_75750812_+	intronic
ADediting_138978	chr1_75750813_+	intronic
ADediting_138979	chr1_75750826_+	intronic
ADediting_138980	chr1_75750843_+	intronic
ADediting_138981	chr1_75750878_+	intronic
ADediting_138982	chr1_75750888_+	intronic
ADediting_138983	chr1_75750890_+	intronic
ADediting_138984	chr1_75750914_+	intronic
ADediting_138985	chr1_75750929_+	intronic
ADediting_138986	chr1_75750932_+	intronic
ADediting_138987	chr1_75750934_+	intronic
ADediting_138988	chr1_75751011_+	intronic
ADediting_138989	chr1_75751086_+	intronic
ADediting_138990	chr1_75751087_+	intronic
ADediting_138991	chr1_75751092_+	intronic
ADediting_138992	chr1_75751265_+	intronic
ADediting_138993	chr1_75751523_+	intronic
ADediting_138994	chr1_75751543_+	intronic
ADediting_138995	chr1_75751552_+	intronic
ADediting_138996	chr1_75751560_+	intronic
ADediting_138997	chr1_75751660_+	intronic
ADediting_138998	chr1_75751767_+	intronic
ADediting_138999	chr1_75758260_+	intronic
ADediting_139000	chr1_75759739_+	intronic
ADediting_139001	chr1_75759742_+	intronic
ADediting_139002	chr1_75759748_+	intronic
ADediting_139003	chr1_75759762_+	intronic
ADediting_139004	chr1_75759801_+	intronic
ADediting_139005	chr1_75759841_+	intronic
ADediting_139006	chr1_75759883_+	intronic
ADediting_139007	chr1_75759895_+	intronic
ADediting_139008	chr1_75759935_+	intronic
ADediting_139009	chr1_75759943_+	intronic
ADediting_139010	chr1_75760016_+	intronic
ADediting_139011	chr1_75760100_+	intronic
ADediting_139012	chr1_75760165_+	intronic
ADediting_139013	chr1_75760166_+	intronic
ADediting_139014	chr1_75760211_+	intronic
ADediting_139015	chr1_75760233_+	intronic
ADediting_139016	chr1_75760243_+	intronic
ADediting_139017	chr1_75760311_+	intronic
ADediting_139018	chr1_75760328_+	intronic
ADediting_139019	chr1_75760332_+	intronic
ADediting_139020	chr1_75760333_+	intronic
ADediting_139021	chr1_75760334_+	intronic
ADediting_139022	chr1_75760354_+	intronic
ADediting_139023	chr1_75760363_+	intronic
ADediting_139024	chr1_75760367_+	intronic
ADediting_139025	chr1_75760375_+	intronic
ADediting_139026	chr1_75760403_+	intronic
ADediting_139027	chr1_75760404_+	intronic
ADediting_139028	chr1_75760412_+	intronic
ADediting_139029	chr1_75760486_+	intronic
ADediting_139030	chr1_75760935_+	intronic
ADediting_139031	chr1_75760951_+	intronic
ADediting_139032	chr1_75760952_+	intronic
ADediting_139033	chr1_75760966_+	intronic
ADediting_139034	chr1_75760974_+	intronic
ADediting_139035	chr1_75760975_+	intronic
ADediting_139036	chr1_75760978_+	intronic
ADediting_139037	chr1_75761028_+	intronic
ADediting_1521478	chr1_75726193_+	intronic
ADediting_1521479	chr1_75726198_+	intronic
ADediting_1521480	chr1_75726243_+	intronic
ADediting_1521481	chr1_75726861_+	intronic
ADediting_1521482	chr1_75750875_+	intronic
ADediting_1521483	chr1_75760528_+	intronic
ADediting_1602384	chr1_75730061_+	intronic
ADediting_1602385	chr1_75730129_+	intronic
ADediting_1602386	chr1_75746732_+	intronic
ADediting_1602387	chr1_75746748_+	intronic
ADediting_1602388	chr1_75746764_+	intronic

Repat-regional RNA editing(s).

ADeditome ID	Position	Repeat family	Repeat sub family	Repeat name
ADediting_138857	chr1_75726232_+	SINE	Alu	Name=AluSz6
ADediting_138858	chr1_75726247_+	SINE	Alu	Name=AluSz6
ADediting_138859	chr1_75726248_+	SINE	Alu	Name=AluSz6
ADediting_138860	chr1_75726249_+	SINE	Alu	Name=AluSz6
ADediting_138861	chr1_75726250_+	SINE	Alu	Name=AluSz6
ADediting_138862	chr1_75726252_+	SINE	Alu	Name=AluSz6
ADediting_138863	chr1_75726258_+	SINE	Alu	Name=AluSz6
ADediting_138864	chr1_75726259_+	SINE	Alu	Name=AluSz6
ADediting_138865	chr1_75726262_+	SINE	Alu	Name=AluSz6
ADediting_138866	chr1_75726270_+	SINE	Alu	Name=AluSz6
ADediting_138867	chr1_75726275_+	SINE	Alu	Name=AluSz6
ADediting_138868	chr1_75726289_+	SINE	Alu	Name=AluSz6
ADediting_138869	chr1_75726294_+	SINE	Alu	Name=AluSz6
ADediting_138870	chr1_75726856_+	SINE	Alu	Name=AluSg
ADediting_138871	chr1_75726860_+	SINE	Alu	Name=AluSg
ADediting_138872	chr1_75726885_+	SINE	Alu	Name=AluSg
ADediting_138873	chr1_75726962_+	SINE	Alu	Name=AluSg
ADediting_138874	chr1_75726971_+	SINE	Alu	Name=AluSg
ADediting_138875	chr1_75726988_+	SINE	Alu	Name=AluSg
ADediting_138876	chr1_75727025_+	SINE	Alu	Name=AluSg
ADediting_138877	chr1_75727050_+	SINE	Alu	Name=AluSg
ADediting_138878	chr1_75727065_+	SINE	Alu	Name=AluSg
ADediting_138879	chr1_75729523_+	SINE	Alu	Name=AluSz6
ADediting_138880	chr1_75729574_+	SINE	Alu	Name=AluSz6
ADediting_138881	chr1_75729666_+	SINE	Alu	Name=AluSz6
ADediting_138882	chr1_75729953_+	SINE	Alu	Name=AluSz
ADediting_138883	chr1_75729975_+	SINE	Alu	Name=AluSz
ADediting_138884	chr1_75729994_+	SINE	Alu	Name=AluSz
ADediting_138885	chr1_75729995_+	SINE	Alu	Name=AluSz
ADediting_138886	chr1_75730012_+	SINE	Alu	Name=AluSz
ADediting_138887	chr1_75730020_+	SINE	Alu	Name=AluSz
ADediting_138888	chr1_75730021_+	SINE	Alu	Name=AluSz
ADediting_138889	chr1_75730029_+	SINE	Alu	Name=AluSz
ADediting_138890	chr1_75730034_+	SINE	Alu	Name=AluSz
ADediting_138891	chr1_75730036_+	SINE	Alu	Name=AluSz
ADediting_138892	chr1_75730060_+	SINE	Alu	Name=AluSz
ADediting_138893	chr1_75730067_+	SINE	Alu	Name=AluSz
ADediting_138894	chr1_75730069_+	SINE	Alu	Name=AluSz
ADediting_138895	chr1_75730075_+	SINE	Alu	Name=AluSz
ADediting_138896	chr1_75730078_+	SINE	Alu	Name=AluSz
ADediting_138897	chr1_75730117_+	SINE	Alu	Name=AluSz
ADediting_138898	chr1_75730130_+	SINE	Alu	Name=AluSz
ADediting_138899	chr1_75730138_+	SINE	Alu	Name=AluSz
ADediting_138900	chr1_75730558_+	SINE	Alu	Name=AluJr4
ADediting_138901	chr1_75730559_+	SINE	Alu	Name=AluJr4
ADediting_138902	chr1_75730561_+	SINE	Alu	Name=AluJr4
ADediting_138903	chr1_75730565_+	SINE	Alu	Name=AluJr4
ADediting_138904	chr1_75730573_+	SINE	Alu	Name=AluJr4
ADediting_138905	chr1_75730581_+	SINE	Alu	Name=AluJr4
ADediting_138906	chr1_75730634_+	SINE	Alu	Name=AluJr4
ADediting_138907	chr1_75730650_+	SINE	Alu	Name=AluJr4
ADediting_138908	chr1_75730655_+	SINE	Alu	Name=AluJr4
ADediting_138909	chr1_75730673_+	SINE	Alu	Name=AluJr4
ADediting_138910	chr1_75730679_+	SINE	Alu	Name=AluJr4
ADediting_138911	chr1_75730729_+	SINE	Alu	Name=AluJr4
ADediting_138912	chr1_75730779_+	SINE	Alu	Name=AluJr4
ADediting_138913	chr1_75730789_+	SINE	Alu	Name=AluJr4
ADediting_138914	chr1_75730790_+	SINE	Alu	Name=AluJr4
ADediting_138915	chr1_75730795_+	SINE	Alu	Name=AluJr4
ADediting_138917	chr1_75731032_+	SINE	Alu	Name=AluYc
ADediting_138918	chr1_75731037_+	SINE	Alu	Name=AluYc
ADediting_138919	chr1_75731132_+	SINE	Alu	Name=AluYc
ADediting_138920	chr1_75731158_+	SINE	Alu	Name=AluYc
ADediting_138921	chr1_75731164_+	SINE	Alu	Name=AluYc
ADediting_138922	chr1_75731172_+	SINE	Alu	Name=AluYc
ADediting_138923	chr1_75731181_+	SINE	Alu	Name=AluYc
ADediting_138924	chr1_75731183_+	SINE	Alu	Name=AluYc
ADediting_138925	chr1_75731185_+	SINE	Alu	Name=AluYc
ADediting_138926	chr1_75731747_+	SINE	Alu	Name=FLAM_C
ADediting_138927	chr1_75731783_+	SINE	Alu	Name=FLAM_C
ADediting_138928	chr1_75731796_+	SINE	Alu	Name=FLAM_C
ADediting_138929	chr1_75731823_+	SINE	Alu	Name=FLAM_C
ADediting_138930	chr1_75731824_+	SINE	Alu	Name=FLAM_C
ADediting_138931	chr1_75731842_+	SINE	Alu	Name=FLAM_C
ADediting_138932	chr1_75731918_+	SINE	Alu	Name=AluJb
ADediting_138933	chr1_75731919_+	SINE	Alu	Name=AluJb
ADediting_138934	chr1_75731951_+	SINE	Alu	Name=AluJb
ADediting_138935	chr1_75731968_+	SINE	Alu	Name=AluJb
ADediting_138936	chr1_75731973_+	SINE	Alu	Name=AluJb
ADediting_138937	chr1_75731987_+	SINE	Alu	Name=AluJb
ADediting_138938	chr1_75731991_+	SINE	Alu	Name=AluJb
ADediting_138939	chr1_75731992_+	SINE	Alu	Name=AluJb
ADediting_138940	chr1_75731999_+	SINE	Alu	Name=AluJb
ADediting_138941	chr1_75732005_+	SINE	Alu	Name=AluJb
ADediting_138942	chr1_75732037_+	SINE	Alu	Name=AluJb
ADediting_138943	chr1_75732041_+	SINE	Alu	Name=AluJb
ADediting_138944	chr1_75732049_+	SINE	Alu	Name=AluJb
ADediting_138945	chr1_75732062_+	SINE	Alu	Name=AluJb
ADediting_138946	chr1_75732067_+	SINE	Alu	Name=AluJb
ADediting_138947	chr1_75732071_+	SINE	Alu	Name=AluJb
ADediting_138948	chr1_75732072_+	SINE	Alu	Name=AluJb
ADediting_138949	chr1_75732091_+	SINE	Alu	Name=AluJb
ADediting_138950	chr1_75732135_+	SINE	Alu	Name=AluJb
ADediting_138951	chr1_75732137_+	SINE	Alu	Name=AluJb
ADediting_138952	chr1_75734044_+	SINE	Alu	Name=AluSx
ADediting_138953	chr1_75735145_+	SINE	Alu	Name=AluSz
ADediting_138954	chr1_75735193_+	SINE	Alu	Name=AluSz
ADediting_138955	chr1_75735195_+	SINE	Alu	Name=AluSz
ADediting_138956	chr1_75735196_+	SINE	Alu	Name=AluSz
ADediting_138957	chr1_75735209_+	SINE	Alu	Name=AluSz
ADediting_138958	chr1_75735251_+	SINE	Alu	Name=AluSz
ADediting_138959	chr1_75735271_+	SINE	Alu	Name=AluSz
ADediting_138960	chr1_75735643_+	SINE	Alu	Name=AluSx
ADediting_138961	chr1_75735756_+	SINE	Alu	Name=AluSx
ADediting_138962	chr1_75735894_+	SINE	Alu	Name=AluJo
ADediting_138963	chr1_75737195_+	SINE	Alu	Name=FLAM_C,SVA_A
ADediting_138964	chr1_75738010_+	SINE	Alu	Name=AluSc8
ADediting_138965	chr1_75738034_+	SINE	Alu	Name=AluSc8
ADediting_138966	chr1_75738042_+	SINE	Alu	Name=AluSc8
ADediting_138967	chr1_75738108_+	SINE	Alu	Name=AluSc8
ADediting_138968	chr1_75738190_+	SINE	Alu	Name=AluSc8
ADediting_138969	chr1_75738317_+	SINE	Alu	Name=AluSx1
ADediting_138970	chr1_75738411_+	SINE	Alu	Name=AluSx1
ADediting_138971	chr1_75738450_+	SINE	Alu	Name=AluSx1
ADediting_138972	chr1_75738456_+	SINE	Alu	Name=AluSx1
ADediting_138973	chr1_75745278_+	SINE	Alu	Name=AluJb
ADediting_138974	chr1_75747566_+	SINE	Alu	Name=AluJb
ADediting_138975	chr1_75747572_+	SINE	Alu	Name=AluJb
ADediting_138976	chr1_75750797_+	SINE	Alu	Name=AluSg
ADediting_138977	chr1_75750812_+	SINE	Alu	Name=AluSg
ADediting_138978	chr1_75750813_+	SINE	Alu	Name=AluSg
ADediting_138979	chr1_75750826_+	SINE	Alu	Name=AluSg
ADediting_138980	chr1_75750843_+	SINE	Alu	Name=AluSg
ADediting_138981	chr1_75750878_+	SINE	Alu	Name=AluSg
ADediting_138982	chr1_75750888_+	SINE	Alu	Name=AluSg
ADediting_138983	chr1_75750890_+	SINE	Alu	Name=AluSg
ADediting_138984	chr1_75750914_+	SINE	Alu	Name=AluSg
ADediting_138985	chr1_75750929_+	SINE	Alu	Name=AluSg
ADediting_138986	chr1_75750932_+	SINE	Alu	Name=AluSg
ADediting_138987	chr1_75750934_+	SINE	Alu	Name=AluSg
ADediting_138988	chr1_75751011_+	SINE	Alu	Name=AluSg
ADediting_138989	chr1_75751086_+	SINE	Alu	Name=AluY
ADediting_138990	chr1_75751087_+	SINE	Alu	Name=AluY
ADediting_138991	chr1_75751092_+	SINE	Alu	Name=AluY
ADediting_138992	chr1_75751265_+	SINE	Alu	Name=AluY
ADediting_138993	chr1_75751523_+	SINE	Alu	Name=AluSz
ADediting_138994	chr1_75751543_+	SINE	Alu	Name=AluSz
ADediting_138995	chr1_75751552_+	SINE	Alu	Name=AluSz
ADediting_138996	chr1_75751560_+	SINE	Alu	Name=AluSz
ADediting_138997	chr1_75751660_+	SINE	Alu	Name=AluSz
ADediting_138998	chr1_75751767_+	SINE	Alu	Name=AluSz
ADediting_138999	chr1_75758260_+	SINE	Alu	Name=AluSq2
ADediting_139000	chr1_75759739_+	SINE	Alu	Name=AluSp
ADediting_139001	chr1_75759742_+	SINE	Alu	Name=AluSp
ADediting_139002	chr1_75759748_+	SINE	Alu	Name=AluSp
ADediting_139003	chr1_75759762_+	SINE	Alu	Name=AluSp
ADediting_139004	chr1_75759801_+	SINE	Alu	Name=AluSp
ADediting_139005	chr1_75759841_+	SINE	Alu	Name=AluSp
ADediting_139006	chr1_75759883_+	SINE	Alu	Name=AluSp
ADediting_139007	chr1_75759895_+	SINE	Alu	Name=AluSp
ADediting_139008	chr1_75759935_+	SINE	Alu	Name=AluSp
ADediting_139009	chr1_75759943_+	SINE	Alu	Name=AluSp
ADediting_139010	chr1_75760016_+	SINE	Alu	Name=AluJo
ADediting_139011	chr1_75760100_+	SINE	Alu	Name=AluJo
ADediting_139012	chr1_75760165_+	SINE	Alu	Name=AluSx
ADediting_139013	chr1_75760166_+	SINE	Alu	Name=AluSx
ADediting_139014	chr1_75760211_+	SINE	Alu	Name=AluSx
ADediting_139015	chr1_75760233_+	SINE	Alu	Name=AluSx
ADediting_139016	chr1_75760243_+	SINE	Alu	Name=AluSx
ADediting_139017	chr1_75760311_+	SINE	Alu	Name=AluSx
ADediting_139018	chr1_75760328_+	SINE	Alu	Name=AluSx
ADediting_139019	chr1_75760332_+	SINE	Alu	Name=AluSx
ADediting_139020	chr1_75760333_+	SINE	Alu	Name=AluSx
ADediting_139021	chr1_75760334_+	SINE	Alu	Name=AluSx
ADediting_139022	chr1_75760354_+	SINE	Alu	Name=AluSx
ADediting_139023	chr1_75760363_+	SINE	Alu	Name=AluSx
ADediting_139024	chr1_75760367_+	SINE	Alu	Name=AluSx
ADediting_139025	chr1_75760375_+	SINE	Alu	Name=AluSx
ADediting_139026	chr1_75760403_+	SINE	Alu	Name=AluSx
ADediting_139027	chr1_75760404_+	SINE	Alu	Name=AluSx
ADediting_139028	chr1_75760412_+	SINE	Alu	Name=AluSx
ADediting_139029	chr1_75760486_+	SINE	Alu	Name=AluJo
ADediting_139030	chr1_75760935_+	SINE	Alu	Name=AluJr
ADediting_139031	chr1_75760951_+	SINE	Alu	Name=AluJr
ADediting_139032	chr1_75760952_+	SINE	Alu	Name=AluJr
ADediting_139033	chr1_75760966_+	SINE	Alu	Name=AluJr
ADediting_139034	chr1_75760974_+	SINE	Alu	Name=AluJr
ADediting_139035	chr1_75760975_+	SINE	Alu	Name=AluJr
ADediting_139036	chr1_75760978_+	SINE	Alu	Name=AluJr
ADediting_139037	chr1_75761028_+	SINE	Alu	Name=AluJr
ADediting_1521478	chr1_75726193_+	SINE	Alu	Name=AluSz6
ADediting_1521479	chr1_75726198_+	SINE	Alu	Name=AluSz6
ADediting_1521480	chr1_75726243_+	SINE	Alu	Name=AluSz6
ADediting_1521481	chr1_75726861_+	SINE	Alu	Name=AluSg
ADediting_1521482	chr1_75750875_+	SINE	Alu	Name=AluSg
ADediting_1521483	chr1_75760528_+	SINE	Alu	Name=AluJo
ADediting_1602384	chr1_75730061_+	SINE	Alu	Name=AluSz
ADediting_1602385	chr1_75730129_+	SINE	Alu	Name=AluSz
ADediting_1602386	chr1_75746732_+	SINE	Alu	Name=AluJo
ADediting_1602387	chr1_75746748_+	SINE	Alu	Name=AluJo
ADediting_1602388	chr1_75746764_+	SINE	Alu	Name=AluJo

Top

RNA A-to-I editing events in the alternative splicing sites for ACADM

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	ADeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
ES	ADediting_138983	chr1_75750890_+	75750889:75750897	5ss	2e	CAGGTGCGC	9.10	CGGGTGCGC	6.64

Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for ACADM

Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

- Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

ADeditome ID

Chr

Positoing

Skipped exon

ENSG

ENSTs

Top

Protein coding region RNA A-to-I editings for ACADM

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

Top

The effects of the RNA editing to the miRNA binding sites for ACADM

RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_138976

chr1_75750797_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-508-5p

chr1

75750795

75750801

7mer-m8

75750778

75750802

148

-21.76

ADediting_138976

chr1_75750797_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-6512-3p

chr1

75750793

75750799

7mer-m8

75750779

75750800

146

-18.79

ADediting_138976

chr1_75750797_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-6720-5p

chr1

75750793

75750799

7mer-m8

75750778

75750800

147

-25.85

ADediting_138976

chr1_75750797_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-6849-3p

chr1

75750792

75750799

8mer-1a

75750779

75750799

150

-18.23

ADediting_138976

chr1_75750797_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-766-3p

chr1

75750794

75750800

7mer-m8

75750779

75750801

151

-25.09

ADediting_138978

chr1_75750813_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-6529-3p

chr1

75750807

75750813

7mer-m8

75750792

75750814

151

-16.29

ADediting_138978

chr1_75750813_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-6889-3p

chr1

75750807

75750813

7mer-m8

75750794

75750814

151

-16.82

ADediting_138978

chr1_75750813_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-873-3p

chr1

75750811

75750817

7mer-m8

75750798

75750818

141

-14.7

ADediting_138980

chr1_75750843_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-1247-3p

chr1

75750838

75750844

7mer-m8

75750823

75750845

166

-31.49

ADediting_138981

chr1_75750878_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-1255b-2-3p

chr1

75750874

75750880

7mer-m8

75750860

75750881

142

-10.54

ADediting_138981

chr1_75750878_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-3614-5p

chr1

75750872

75750878

7mer-m8

75750856

75750879

152

-25.27

ADediting_138982

chr1_75750888_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-17-3p

chr1

75750885

75750891

7mer-m8

75750870

75761122

150

-20.88

ADediting_138982

chr1_75750888_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-584-3p

chr1

75750882

75750888

7mer-m8

75750870

75750889

141

-14.71

RNA A-to-I editing in lncRNA lost miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_138976

chr1_75750797_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-1251-5p

chr1

75750794

75750800

7mer-m8

75750777

75750801

151

-21.62

ADediting_138977

chr1_75750812_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-5186

chr1

75750811

75750817

7mer-m8

75750798

75750818

140

-10.89

ADediting_138978

chr1_75750813_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-5186

chr1

75750811

75750817

7mer-m8

75750798

75750818

140

-10.89

ADediting_138979

chr1_75750826_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-4318

chr1

75750824

75750830

7mer-m8

75750814

75750831

143

-13.28

ADediting_138980

chr1_75750843_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-6771-5p

chr1

75750837

75750843

7mer-m8

75750824

75750844

147

-26.69

ADediting_138981

chr1_75750878_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-4301

chr1

75750877

75750884

8mer-1a

75750865

75750884

155

-18.95

ADediting_138982

chr1_75750888_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-20b-3p

chr1

75750885

75750891

7mer-m8

75750870

75761122

149

-19.7

ADediting_138983

chr1_75750890_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-20b-3p

chr1

75750885

75750891

7mer-m8

75750870

75761122

149

-19.7

ADediting_1521482

chr1_75750875_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-12126

chr1

75750871

75750878

8mer-1a

75750855

75750878

147

-13.23

ADediting_1521482

chr1_75750875_+

ENSG00000117054.13

ENST00000481374.1

ACADM-205

hsa-miR-887-5p

chr1

75750869

75750875

7mer-m8

75750857

75750876

143

-19.73

RNA A-to-I editing in miRNAs gained binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_1535953

chr14_101045971_+

ENSG00000117054.13

ENST00000370841.8

ACADM-202

hsa-miR-381-3p

chr1

75763553

75763559

7mer-m8

75763538

75763560

147

-12.31

ADediting_1535953

chr14_101045971_+

ENSG00000117054.13

ENST00000541113.5

ACADM-218

hsa-miR-381-3p

chr1

75763553

75763559

7mer-m8

75763538

75763560

147

-12.31

ADediting_1535954

chr14_101045974_+

ENSG00000117054.13

ENST00000370841.8

ACADM-202

hsa-miR-381-3p

chr1

75763553

75763559

7mer-m8

75763538

75763560

147

-12.31

ADediting_1535954

chr14_101045974_+

ENSG00000117054.13

ENST00000541113.5

ACADM-218

hsa-miR-381-3p

chr1

75763553

75763559

7mer-m8

75763538

75763560

147

-12.31

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ACADM

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000481374.1	lncRNA

RNA A-to-I editing in miRNA.

ADeditom_ID

ENST

mir_ID

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

RNA A-to-I editing in mRNA.

ADeditom_ID

ENST

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

RNA A-to-I editing in lncRNA.

ADeditom_ID	ENST	Editing_Information	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
ADediting_138976	ENST00000481374.1	chr1_75750797_+	124	-170.00	-169.30	-180.60
ADediting_138977	ENST00000481374.1	chr1_75750812_+	139	-170.50	-169.30	-180.60
ADediting_138978	ENST00000481374.1	chr1_75750813_+	140	-169.30	-169.30	-180.60
ADediting_138979	ENST00000481374.1	chr1_75750826_+	153	-168.80	-169.30	-180.60
ADediting_138980	ENST00000481374.1	chr1_75750843_+	170	-168.50	-169.30	-180.60
ADediting_1521482	ENST00000481374.1	chr1_75750875_+	202	-170.10	-169.30	-180.60
ADediting_138981	ENST00000481374.1	chr1_75750878_+	205	-169.30	-169.30	-180.60
ADediting_138982	ENST00000481374.1	chr1_75750888_+	215	-169.30	-169.30	-180.60
ADediting_138983	ENST00000481374.1	chr1_75750890_+	217	-169.30	-169.30	-180.60

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Relation with ADAR for ACADM

Correlation between ADAR gene expression and RNA editing frequency

Tissue	ADeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
DLPFC	ADediting_138957	chr1_75735209_+	0.619648581614227	-0.0282993739054519	0.0198414251355394	-0.132249882152472	1.28650535540669e-10	0.354626646492337
CER	ADediting_138976	chr1_75750797_+	0.000115618039385406	0.30959884582559	0.00224958260677031	0.247625440371637	0.0683666116003676	0.149227229225721
CER	ADediting_138981	chr1_75750878_+	0.00017552050293979	0.301693375208637	0.00970053088029901	0.210561051407958	0.698426399061843	0.0318935492644457
DLPFC	ADediting_139000	chr1_75759739_+	0.667864763952828	0.0244653110364861	0.447509741546397	-0.0432955291826529	1.0898573157649e-09	0.337370543955627
DLPFC	ADediting_139002	chr1_75759748_+	0.535877253142234	-0.0352918246026887	0.150088516280269	-0.0819356405351423	4.19441633932436e-09	0.325913535910788
DLPFC	ADediting_139005	chr1_75759841_+	0.264705064732506	0.0635396683567457	0.449402342042978	-0.0431154971266967	2.76623717405144e-10	0.34856418365498
DLPFC	ADediting_139008	chr1_75759935_+	0.503898098094872	0.0381009389937101	0.145571358520227	-0.0828510643102024	1.81982537546362e-19	0.482319514902029
DLPFC	ADediting_139009	chr1_75759943_+	0.365574696780033	0.0515629370867813	0.392893195166745	-0.0486935726871709	8.6106460840158e-19	0.474268516331342
DLPFC	ADediting_139014	chr1_75760211_+	0.769125532768923	-0.0167372013444884	0.176587080170872	-0.0769478729138313	1.03254092827694e-08	0.31798095031085
DLPFC	ADediting_139027	chr1_75760404_+	0.847912859243749	-0.0109363482152462	0.0824496579325648	-0.0987925462041705	5.36201194248589e-12	0.37850806301235

Correlation between ADAR gene expression and this gene's expression

Tissue	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
DLPFC	1.86777701265483e-43	0.680250666572661	9.70790786129803e-29	0.57552551883174	0.0308205880133859	0.12267660358452
AC	4.47005298814317e-72	0.853255152256027	1.94990171142866e-40	0.715049480110269	9.66124369931406e-21	0.544992558657089
PCC	5.43837878324753e-23	0.635405263478368	1.06656334304976e-19	0.595287621699674	0.000355326066866872	0.255771540245019
CER	4.97475274543249e-30	0.764594433432677	3.241361837698e-10	0.484811098933163	0.0213786636533485	0.187790708166471
TCX	1.41330994553215e-26	0.733304499413851	1.73326363111292e-07	0.41111154680182	0.00104849327200669	0.264997173003391
FP	2.38567326811953e-30	0.725316294457286	2.51437588607924e-25	0.67817699961515	0.0335270065227645	0.159431740099699
IFG	3.25268591804112e-05	0.731535376849938	0.013226132493898	0.488487292655115	0.151165311046749	0.295758301122414
PG	5.02060383455381e-54	0.853692551461059	2.10715938107735e-23	0.646578137932016	0.566826165808074	0.042260873272243
STG	1.37903564702858e-15	0.736696384458763	4.43063372843502e-15	0.727771233250779	0.366807143880911	0.0997159873521573

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Relation with AD stages for ACADM

Correlation between AD stages and RNA editing frequency

Tissue

ADeditomID

position

P-val

Coeff.

Correlation between AD stages and this gene's expression

Tissue	P-val	Coeff.
TCX	4.72250461093426e-06	0.428021875700955

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RelatedDrugs for ACADM

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for ACADM

Diseases associated with this gene.
(DisGeNet 4.0)

Gene	Disease ID	Disease name	# pubmeds	Source
ACADM	C0220710	Medium-chain acyl-coenzyme A dehydrogenase deficiency	16	CTD_human;ORPHANET;UNIPROT
ACADM	C3714756	Intellectual Disability	8	GENOMICS_ENGLAND
ACADM	C0006142	Malignant neoplasm of breast	1	UNIPROT
ACADM	C0028754	Obesity	1	CTD_human
ACADM	C0043094	Weight Gain	1	CTD_human
ACADM	C0085605	Liver Failure	1	CTD_human
ACADM	C0520459	Necrotizing Enterocolitis	1	CTD_human

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Gene summary for ACADM

RNA A-to-I events for ACADM

RNA editing positional annotations for ACADM using Annovar

RNA A-to-I editing events in the alternative splicing sites for ACADM

Differntial gene expression between RNA A-to-I edited versus non-edited samples for ACADM

Protein coding region RNA A-to-I editings for ACADM

The effects of the RNA editing to the miRNA binding sites for ACADM

The effects of the RNA editing to the stability of the RNA structures for ACADM

Relation with ADAR for ACADM

Relation with AD stages for ACADM

RelatedDrugs for ACADM

RelatedDiseases for ACADM

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited versus non-edited samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with AD stages
	Related drugs with this gene
	Related diseases with this gene