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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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Gene summary for HFE |
 Gene summary |
| Gene information | Gene symbol | HFE | Gene ID | 3077 |
| Gene name | homeostatic iron regulator | |
| Synonyms | HFE1|HH|HLA-H|MVCD7|TFQTL2 | |
| Cytomap | 6p22.2 | |
| Type of gene | protein-coding | |
| Description | hereditary hemochromatosis proteinMHC class I-like protein HFEhereditary hemochromatosis protein HLA-Hhigh Fe | |
| Modification date | 20200328 | |
| UniProtAcc | Q30201, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| HFE | GO:0006879 | cellular iron ion homeostasis | 10085150 |
| HFE | GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation | 24904118 |
| HFE | GO:0030509 | BMP signaling pathway | 24904118 |
| HFE | GO:1900121 | negative regulation of receptor binding | 9465039 |
| HFE | GO:2000059 | negative regulation of ubiquitin-dependent protein catabolic process | 24904118 |
| HFE | GO:2000272 | negative regulation of signaling receptor activity | 9465039 |
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RNA A-to-I events for HFE |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_1253197(26094800, +), ADediting_1253198(26095226, +), ADediting_1253199(26095234, +), ADediting_1253200(26095235, +), ADediting_1253201(26095240, +), ADediting_1253202(26095256, +), ADediting_1253203(26095258, +), ADediting_1253204(26095289, +), ADediting_1253205(26095312, +), ADediting_1253206(26095317, +), ADediting_1253207(26095323, +), ADediting_1253208(26095324, +), ADediting_1253209(26095328, +), ADediting_1253210(26095329, +), ADediting_1253211(26095342, +), ADediting_1253212(26095368, +), ADediting_1253213(26095374, +), ADediting_1253214(26095378, +), ADediting_1253215(26095385, +), ADediting_1253216(26095401, +), ADediting_1253217(26095409, +), ADediting_1253218(26095410, +), ADediting_1253219(26095414, +), ADediting_1253220(26095421, +), ADediting_1253221(26095464, +), ADediting_1253222(26096163, +), ADediting_1253223(26096170, +), ADediting_1253224(26096190, +), ADediting_1253225(26096227, +), ADediting_1253226(26096233, +), ADediting_1253227(26096234, +), ADediting_1253228(26096238, +), ADediting_1253229(26096251, +), ADediting_1253230(26096259, +), ADediting_1253231(26096260, +), ADediting_1253232(26096263, +), ADediting_1253233(26096273, +), ADediting_1253234(26096275, +), ADediting_1253235(26096299, +), ADediting_1253236(26096308, +), ADediting_1253237(26096314, +), ADediting_1253238(26096317, +), ADediting_1253239(26096323, +), ADediting_1253240(26096365, +), ADediting_1253241(26096395, +), ADediting_1253242(26096396, +), ADediting_1253243(26096403, +), ADediting_1253244(26096408, +), ADediting_1253245(26096417, +), ADediting_1583320(26095406, +), ADediting_1583321(26095434, +), ADediting_1583322(26095439, +), ADediting_1583323(26095471, +), ADediting_1583324(26096394, +), |
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RNA editing positional annotations for HFE using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1253197 | chr6_26094800_+ | UTR3 |
| ADediting_1253198 | chr6_26095226_+ | UTR3 |
| ADediting_1253199 | chr6_26095234_+ | UTR3 |
| ADediting_1253200 | chr6_26095235_+ | UTR3 |
| ADediting_1253201 | chr6_26095240_+ | UTR3 |
| ADediting_1253202 | chr6_26095256_+ | UTR3 |
| ADediting_1253203 | chr6_26095258_+ | UTR3 |
| ADediting_1253204 | chr6_26095289_+ | UTR3 |
| ADediting_1253205 | chr6_26095312_+ | UTR3 |
| ADediting_1253206 | chr6_26095317_+ | UTR3 |
| ADediting_1253207 | chr6_26095323_+ | UTR3 |
| ADediting_1253208 | chr6_26095324_+ | UTR3 |
| ADediting_1253209 | chr6_26095328_+ | UTR3 |
| ADediting_1253210 | chr6_26095329_+ | UTR3 |
| ADediting_1253211 | chr6_26095342_+ | UTR3 |
| ADediting_1253212 | chr6_26095368_+ | UTR3 |
| ADediting_1253213 | chr6_26095374_+ | UTR3 |
| ADediting_1253214 | chr6_26095378_+ | UTR3 |
| ADediting_1253215 | chr6_26095385_+ | UTR3 |
| ADediting_1253216 | chr6_26095401_+ | UTR3 |
| ADediting_1253217 | chr6_26095409_+ | UTR3 |
| ADediting_1253218 | chr6_26095410_+ | UTR3 |
| ADediting_1253219 | chr6_26095414_+ | UTR3 |
| ADediting_1253220 | chr6_26095421_+ | UTR3 |
| ADediting_1253221 | chr6_26095464_+ | UTR3 |
| ADediting_1253222 | chr6_26096163_+ | UTR3 |
| ADediting_1253223 | chr6_26096170_+ | UTR3 |
| ADediting_1253224 | chr6_26096190_+ | UTR3 |
| ADediting_1253225 | chr6_26096227_+ | UTR3 |
| ADediting_1253226 | chr6_26096233_+ | UTR3 |
| ADediting_1253227 | chr6_26096234_+ | UTR3 |
| ADediting_1253228 | chr6_26096238_+ | UTR3 |
| ADediting_1253229 | chr6_26096251_+ | UTR3 |
| ADediting_1253230 | chr6_26096259_+ | UTR3 |
| ADediting_1253231 | chr6_26096260_+ | UTR3 |
| ADediting_1253232 | chr6_26096263_+ | UTR3 |
| ADediting_1253233 | chr6_26096273_+ | UTR3 |
| ADediting_1253234 | chr6_26096275_+ | UTR3 |
| ADediting_1253235 | chr6_26096299_+ | UTR3 |
| ADediting_1253236 | chr6_26096308_+ | UTR3 |
| ADediting_1253237 | chr6_26096314_+ | UTR3 |
| ADediting_1253238 | chr6_26096317_+ | UTR3 |
| ADediting_1253239 | chr6_26096323_+ | UTR3 |
| ADediting_1253240 | chr6_26096365_+ | UTR3 |
| ADediting_1253241 | chr6_26096395_+ | UTR3 |
| ADediting_1253242 | chr6_26096396_+ | UTR3 |
| ADediting_1253243 | chr6_26096403_+ | UTR3 |
| ADediting_1253244 | chr6_26096408_+ | UTR3 |
| ADediting_1253245 | chr6_26096417_+ | UTR3 |
| ADediting_1583320 | chr6_26095406_+ | UTR3 |
| ADediting_1583321 | chr6_26095434_+ | UTR3 |
| ADediting_1583322 | chr6_26095439_+ | UTR3 |
| ADediting_1583323 | chr6_26095471_+ | UTR3 |
| ADediting_1583324 | chr6_26096394_+ | UTR3 |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1253197 | chr6_26094800_+ | DNA | hAT-Tip100 | Name=MER91B |
| ADediting_1253198 | chr6_26095226_+ | SINE | Alu | Name=AluY |
| ADediting_1253199 | chr6_26095234_+ | SINE | Alu | Name=AluY |
| ADediting_1253200 | chr6_26095235_+ | SINE | Alu | Name=AluY |
| ADediting_1253201 | chr6_26095240_+ | SINE | Alu | Name=AluY |
| ADediting_1253202 | chr6_26095256_+ | SINE | Alu | Name=AluY |
| ADediting_1253203 | chr6_26095258_+ | SINE | Alu | Name=AluY |
| ADediting_1253204 | chr6_26095289_+ | SINE | Alu | Name=AluY |
| ADediting_1253205 | chr6_26095312_+ | SINE | Alu | Name=AluY |
| ADediting_1253206 | chr6_26095317_+ | SINE | Alu | Name=AluY |
| ADediting_1253207 | chr6_26095323_+ | SINE | Alu | Name=AluY |
| ADediting_1253208 | chr6_26095324_+ | SINE | Alu | Name=AluY |
| ADediting_1253209 | chr6_26095328_+ | SINE | Alu | Name=AluY |
| ADediting_1253210 | chr6_26095329_+ | SINE | Alu | Name=AluY |
| ADediting_1253211 | chr6_26095342_+ | SINE | Alu | Name=AluY |
| ADediting_1253212 | chr6_26095368_+ | SINE | Alu | Name=AluY |
| ADediting_1253213 | chr6_26095374_+ | SINE | Alu | Name=AluY |
| ADediting_1253214 | chr6_26095378_+ | SINE | Alu | Name=AluY |
| ADediting_1253215 | chr6_26095385_+ | SINE | Alu | Name=AluY |
| ADediting_1253216 | chr6_26095401_+ | SINE | Alu | Name=AluY |
| ADediting_1253217 | chr6_26095409_+ | SINE | Alu | Name=AluY |
| ADediting_1253218 | chr6_26095410_+ | SINE | Alu | Name=AluY |
| ADediting_1253219 | chr6_26095414_+ | SINE | Alu | Name=AluY |
| ADediting_1253220 | chr6_26095421_+ | SINE | Alu | Name=AluY |
| ADediting_1253221 | chr6_26095464_+ | SINE | Alu | Name=AluY |
| ADediting_1253222 | chr6_26096163_+ | SINE | Alu | Name=AluSg |
| ADediting_1253223 | chr6_26096170_+ | SINE | Alu | Name=AluSg |
| ADediting_1253224 | chr6_26096190_+ | SINE | Alu | Name=AluSg |
| ADediting_1253225 | chr6_26096227_+ | SINE | Alu | Name=AluSg |
| ADediting_1253226 | chr6_26096233_+ | SINE | Alu | Name=AluSg |
| ADediting_1253227 | chr6_26096234_+ | SINE | Alu | Name=AluSg |
| ADediting_1253228 | chr6_26096238_+ | SINE | Alu | Name=AluSg |
| ADediting_1253229 | chr6_26096251_+ | SINE | Alu | Name=AluSg |
| ADediting_1253230 | chr6_26096259_+ | SINE | Alu | Name=AluSg |
| ADediting_1253231 | chr6_26096260_+ | SINE | Alu | Name=AluSg |
| ADediting_1253232 | chr6_26096263_+ | SINE | Alu | Name=AluSg |
| ADediting_1253233 | chr6_26096273_+ | SINE | Alu | Name=AluSg |
| ADediting_1253234 | chr6_26096275_+ | SINE | Alu | Name=AluSg |
| ADediting_1253235 | chr6_26096299_+ | SINE | Alu | Name=AluSg |
| ADediting_1253236 | chr6_26096308_+ | SINE | Alu | Name=AluSg |
| ADediting_1253237 | chr6_26096314_+ | SINE | Alu | Name=AluSg |
| ADediting_1253238 | chr6_26096317_+ | SINE | Alu | Name=AluSg |
| ADediting_1253239 | chr6_26096323_+ | SINE | Alu | Name=AluSg |
| ADediting_1253240 | chr6_26096365_+ | SINE | Alu | Name=AluSg |
| ADediting_1253241 | chr6_26096395_+ | SINE | Alu | Name=AluSg |
| ADediting_1253242 | chr6_26096396_+ | SINE | Alu | Name=AluSg |
| ADediting_1253243 | chr6_26096403_+ | SINE | Alu | Name=AluSg |
| ADediting_1253244 | chr6_26096408_+ | SINE | Alu | Name=AluSg |
| ADediting_1253245 | chr6_26096417_+ | SINE | Alu | Name=AluSg |
| ADediting_1583320 | chr6_26095406_+ | SINE | Alu | Name=AluY |
| ADediting_1583321 | chr6_26095434_+ | SINE | Alu | Name=AluY |
| ADediting_1583322 | chr6_26095439_+ | SINE | Alu | Name=AluY |
| ADediting_1583323 | chr6_26095471_+ | SINE | Alu | Name=AluY |
| ADediting_1583324 | chr6_26096394_+ | SINE | Alu | Name=AluSg |
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RNA A-to-I editing events in the alternative splicing sites for HFE |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for HFE |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
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| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for HFE |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for HFE |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000317896.11 | HFE-202 | hsa-miR-148a-3p | chr6 | 26094798 | 26094804 | 7mer-m8 | 26094780 | 26094805 | 147 | -17.07 |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000317896.11 | HFE-202 | hsa-miR-148b-3p | chr6 | 26094798 | 26094804 | 7mer-m8 | 26094788 | 26094805 | 142 | -14.97 |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000317896.11 | HFE-202 | hsa-miR-152-3p | chr6 | 26094798 | 26094804 | 7mer-m8 | 26094785 | 26094805 | 144 | -14.67 |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000349999.8 | HFE-204 | hsa-miR-148a-3p | chr6 | 26094798 | 26094804 | 7mer-m8 | 26094780 | 26094805 | 147 | -17.07 |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000349999.8 | HFE-204 | hsa-miR-148b-3p | chr6 | 26094798 | 26094804 | 7mer-m8 | 26094788 | 26094805 | 142 | -14.97 |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000349999.8 | HFE-204 | hsa-miR-152-3p | chr6 | 26094798 | 26094804 | 7mer-m8 | 26094785 | 26094805 | 144 | -14.67 |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-148a-3p | chr6 | 26094798 | 26094804 | 7mer-m8 | 26094780 | 26094805 | 147 | -17.07 |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-148b-3p | chr6 | 26094798 | 26094804 | 7mer-m8 | 26094788 | 26094805 | 142 | -14.97 |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-152-3p | chr6 | 26094798 | 26094804 | 7mer-m8 | 26094785 | 26094805 | 144 | -14.67 |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000485729.1 | HFE-212 | hsa-miR-148a-3p | chr6 | 26094798 | 26094804 | 7mer-m8 | 26094780 | 26094805 | 147 | -17.07 |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000485729.1 | HFE-212 | hsa-miR-148b-3p | chr6 | 26094798 | 26094804 | 7mer-m8 | 26094788 | 26094805 | 142 | -14.97 |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000485729.1 | HFE-212 | hsa-miR-152-3p | chr6 | 26094798 | 26094804 | 7mer-m8 | 26094785 | 26094805 | 144 | -14.67 |
| ADediting_1253198 | chr6_26095226_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4634 | chr6 | 26095223 | 26095229 | 7mer-m8 | 26095207 | 26095230 | 155 | -34.29 |
| ADediting_1253199 | chr6_26095234_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-513a-5p | chr6 | 26095228 | 26095234 | 7mer-m8 | 26095218 | 26095235 | 144 | -16.68 |
| ADediting_1253199 | chr6_26095234_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-638 | chr6 | 26095233 | 26095239 | 7mer-1a | 26095215 | 26095239 | 159 | -35.56 |
| ADediting_1253200 | chr6_26095235_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-8052 | chr6 | 26095233 | 26095239 | 7mer-1a | 26095221 | 26095239 | 140 | -24.15 |
| ADediting_1253201 | chr6_26095240_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-371a-3p | chr6 | 26095238 | 26095244 | 7mer-m8 | 26095223 | 26095245 | 145 | -17.36 |
| ADediting_1253202 | chr6_26095256_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-10392-5p | chr6 | 26095254 | 26095260 | 7mer-m8 | 26095239 | 26095261 | 149 | -17.27 |
| ADediting_1253203 | chr6_26095258_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-212-5p | chr6 | 26095252 | 26095258 | 7mer-m8 | 26095235 | 26095259 | 162 | -21.74 |
| ADediting_1253204 | chr6_26095289_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6878-3p | chr6 | 26095285 | 26095291 | 7mer-m8 | 26095270 | 26095292 | 150 | -20.85 |
| ADediting_1253205 | chr6_26095312_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-412-3p | chr6 | 26095305 | 26095311 | 7mer-m8 | 26095290 | 26095312 | 151 | -19.82 |
| ADediting_1253205 | chr6_26095312_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6754-3p | chr6 | 26095305 | 26095311 | 7mer-m8 | 26095292 | 26095312 | 144 | -16.46 |
| ADediting_1253206 | chr6_26095317_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-483-5p | chr6 | 26095313 | 26095319 | 7mer-m8 | 26095299 | 26095320 | 140 | -14.01 |
| ADediting_1253207 | chr6_26095323_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-361-5p | chr6 | 26095319 | 26095326 | 8mer-1a | 26095304 | 26095326 | 141 | -17.15 |
| ADediting_1253207 | chr6_26095323_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-374a-3p | chr6 | 26095320 | 26095327 | 8mer-1a | 26095304 | 26095327 | 146 | -9.32 |
| ADediting_1253207 | chr6_26095323_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4756-3p | chr6 | 26095316 | 26095323 | 8mer-1a | 26095304 | 26095323 | 151 | -16.93 |
| ADediting_1253209 | chr6_26095328_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-630 | chr6 | 26095326 | 26095333 | 8mer-1a | 26095313 | 26095333 | 158 | -15.14 |
| ADediting_1253212 | chr6_26095368_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-140-3p | chr6 | 26095363 | 26095369 | 7mer-m8 | 26095347 | 26095370 | 152 | -29.08 |
| ADediting_1253214 | chr6_26095378_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-1207-3p | chr6 | 26095371 | 26095377 | 7mer-m8 | 26095360 | 26095378 | 145 | -13.53 |
| ADediting_1253214 | chr6_26095378_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-646 | chr6 | 26095373 | 26095379 | 7mer-m8 | 26095361 | 26095380 | 148 | -21.05 |
| ADediting_1253215 | chr6_26095385_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-1470 | chr6 | 26095380 | 26095386 | 7mer-m8 | 26095367 | 26095387 | 140 | -20.38 |
| ADediting_1253215 | chr6_26095385_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4290 | chr6 | 26095381 | 26095387 | 7mer-m8 | 26095370 | 26095388 | 140 | -13.95 |
| ADediting_1253215 | chr6_26095385_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4687-5p | chr6 | 26095382 | 26095388 | 7mer-m8 | 26095368 | 26095389 | 145 | -20.77 |
| ADediting_1253216 | chr6_26095401_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4639-3p | chr6 | 26095396 | 26095402 | 7mer-m8 | 26095381 | 26095403 | 152 | -23.94 |
| ADediting_1253216 | chr6_26095401_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6777-3p | chr6 | 26095397 | 26095403 | 7mer-m8 | 26095385 | 26095404 | 164 | -29.74 |
| ADediting_1253217 | chr6_26095409_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-5581-3p | chr6 | 26095403 | 26095409 | 7mer-m8 | 26095388 | 26095410 | 148 | -18 |
| ADediting_1253218 | chr6_26095410_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-10400-3p | chr6 | 26095407 | 26095413 | 7mer-m8 | 26095393 | 26095414 | 140 | -20.37 |
| ADediting_1253218 | chr6_26095410_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4437 | chr6 | 26095406 | 26095413 | 8mer-1a | 26095393 | 26095413 | 145 | -16.69 |
| ADediting_1253218 | chr6_26095410_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4674 | chr6 | 26095407 | 26095413 | 7mer-m8 | 26095394 | 26095414 | 146 | -23.01 |
| ADediting_1253218 | chr6_26095410_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6847-3p | chr6 | 26095404 | 26095410 | 7mer-m8 | 26095390 | 26095411 | 154 | -22.53 |
| ADediting_1253220 | chr6_26095421_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-1281 | chr6 | 26095414 | 26095420 | 7mer-m8 | 26095405 | 26095421 | 145 | -17.85 |
| ADediting_1253221 | chr6_26095464_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-500b-3p | chr6 | 26095461 | 26095468 | 8mer-1a | 26095450 | 26095468 | 155 | -23.07 |
| ADediting_1253222 | chr6_26096163_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-5588-3p | chr6 | 26096160 | 26096166 | 7mer-m8 | 26096149 | 26096167 | 144 | -10.87 |
| ADediting_1253223 | chr6_26096170_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-196a-3p | chr6 | 26096168 | 26096174 | 7mer-m8 | 26096155 | 26096175 | 145 | -12.14 |
| ADediting_1253223 | chr6_26096170_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4797-5p | chr6 | 26096164 | 26096170 | 7mer-m8 | 26096151 | 26096171 | 144 | -11.19 |
| ADediting_1253224 | chr6_26096190_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-324-3p | chr6 | 26096186 | 26096192 | 7mer-m8 | 26096171 | 26096193 | 148 | -24.15 |
| ADediting_1253224 | chr6_26096190_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4252 | chr6 | 26096187 | 26096194 | 8mer-1a | 26096174 | 26096194 | 149 | -22.82 |
| ADediting_1253224 | chr6_26096190_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4793-3p | chr6 | 26096183 | 26096189 | 7mer-m8 | 26096168 | 26096190 | 149 | -19.2 |
| ADediting_1253225 | chr6_26096227_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-1247-3p | chr6 | 26096222 | 26096228 | 7mer-m8 | 26096207 | 26096229 | 148 | -22.7 |
| ADediting_1253227 | chr6_26096234_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6078 | chr6 | 26096230 | 26096237 | 8mer-1a | 26096219 | 26096237 | 149 | -21.5 |
| ADediting_1253228 | chr6_26096238_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-589-5p | chr6 | 26096236 | 26096242 | 7mer-m8 | 26096223 | 26096243 | 150 | -15.69 |
| ADediting_1253229 | chr6_26096251_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6089 | chr6 | 26096249 | 26096255 | 7mer-m8 | 26096233 | 26096256 | 160 | -38.36 |
| ADediting_1253230 | chr6_26096259_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6771-5p | chr6 | 26096253 | 26096259 | 7mer-m8 | 26096241 | 26096260 | 160 | -34.33 |
| ADediting_1253232 | chr6_26096263_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-3614-5p | chr6 | 26096256 | 26096262 | 7mer-m8 | 26096240 | 26096263 | 148 | -24.19 |
| ADediting_1253232 | chr6_26096263_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4691-3p | chr6 | 26096260 | 26096266 | 7mer-m8 | 26096240 | 26096267 | 155 | -27.66 |
| ADediting_1253235 | chr6_26096299_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-34a-3p | chr6 | 26096295 | 26096301 | 7mer-m8 | 26096280 | 26096302 | 145 | -11.29 |
| ADediting_1253239 | chr6_26096323_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-340-3p | chr6 | 26096317 | 26096323 | 7mer-m8 | 26096303 | 26096324 | 149 | -17.74 |
| ADediting_1253239 | chr6_26096323_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6827-3p | chr6 | 26096317 | 26096323 | 7mer-m8 | 26096304 | 26096324 | 153 | -17.53 |
| ADediting_1253240 | chr6_26096365_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-665 | chr6 | 26096358 | 26096364 | 7mer-m8 | 26096344 | 26096365 | 156 | -26.77 |
| ADediting_1253241 | chr6_26096395_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-326 | chr6 | 26096390 | 26096396 | 7mer-m8 | 26096378 | 26096397 | 140 | -14.6 |
| ADediting_1253241 | chr6_26096395_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-330-5p | chr6 | 26096390 | 26096396 | 7mer-m8 | 26096376 | 26096397 | 140 | -22.38 |
| ADediting_1253241 | chr6_26096395_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4314 | chr6 | 26096389 | 26096395 | 7mer-m8 | 26096379 | 26096396 | 140 | -21.61 |
| ADediting_1253241 | chr6_26096395_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-514a-5p | chr6 | 26096391 | 26096397 | 7mer-m8 | 26096375 | 26096398 | 146 | -18.62 |
| ADediting_1253242 | chr6_26096396_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-3189-3p | chr6 | 26096390 | 26096396 | 7mer-m8 | 26096378 | 26096397 | 145 | -25.82 |
| ADediting_1253242 | chr6_26096396_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6813-3p | chr6 | 26096391 | 26096397 | 7mer-m8 | 26096378 | 26096398 | 140 | -12.15 |
| ADediting_1253243 | chr6_26096403_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-7977 | chr6 | 26096398 | 26096404 | 7mer-m8 | 26096388 | 26096405 | 140 | -13.07 |
| ADediting_1253245 | chr6_26096417_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-663b | chr6 | 26096415 | 26096421 | 7mer-m8 | 26096401 | 26096422 | 147 | -26.98 |
| ADediting_1583320 | chr6_26095406_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-122-3p | chr6 | 26095400 | 26095406 | 7mer-m8 | 26095386 | 26095407 | 152 | -14.91 |
| ADediting_1583321 | chr6_26095434_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-324-3p | chr6 | 26095427 | 26095433 | 7mer-m8 | 26095415 | 26095434 | 153 | -25.48 |
| ADediting_1583321 | chr6_26095434_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6075 | chr6 | 26095431 | 26095438 | 8mer-1a | 26095416 | 26095438 | 148 | -24.08 |
| ADediting_1583322 | chr6_26095439_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-941 | chr6 | 26095434 | 26095440 | 7mer-m8 | 26095419 | 26095441 | 156 | -20.88 |
| ADediting_1583324 | chr6_26096394_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6771-5p | chr6 | 26096388 | 26096395 | 8mer-1a | 26096376 | 26096395 | 157 | -31.04 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000317896.11 | HFE-202 | hsa-let-7g-3p | chr6 | 26094795 | 26094801 | 7mer-m8 | 26094781 | 26094802 | 145 | -12.04 |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000317896.11 | HFE-202 | hsa-miR-3177-5p | chr6 | 26094796 | 26094802 | 7mer-m8 | 26094781 | 26094803 | 142 | -12.43 |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000349999.8 | HFE-204 | hsa-let-7g-3p | chr6 | 26094795 | 26094801 | 7mer-m8 | 26094781 | 26094802 | 145 | -12.04 |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000349999.8 | HFE-204 | hsa-miR-3177-5p | chr6 | 26094796 | 26094802 | 7mer-m8 | 26094781 | 26094803 | 142 | -12.43 |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-let-7g-3p | chr6 | 26094795 | 26094801 | 7mer-m8 | 26094781 | 26094802 | 145 | -12.04 |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-3177-5p | chr6 | 26094796 | 26094802 | 7mer-m8 | 26094781 | 26094803 | 142 | -12.43 |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000485729.1 | HFE-212 | hsa-let-7g-3p | chr6 | 26094795 | 26094801 | 7mer-m8 | 26094781 | 26094802 | 145 | -12.04 |
| ADediting_1253197 | chr6_26094800_+ | ENSG00000010704.18 | ENST00000485729.1 | HFE-212 | hsa-miR-3177-5p | chr6 | 26094796 | 26094802 | 7mer-m8 | 26094781 | 26094803 | 142 | -12.43 |
| ADediting_1253198 | chr6_26095226_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6807-5p | chr6 | 26095219 | 26095225 | 7mer-m8 | 26095204 | 26095226 | 144 | -25.48 |
| ADediting_1253199 | chr6_26095234_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-10399-5p | chr6 | 26095229 | 26095235 | 7mer-m8 | 26095215 | 26095236 | 144 | -11.21 |
| ADediting_1253199 | chr6_26095234_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6504-3p | chr6 | 26095229 | 26095235 | 7mer-m8 | 26095215 | 26095236 | 148 | -14.35 |
| ADediting_1253199 | chr6_26095234_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-7151-3p | chr6 | 26095227 | 26095234 | 8mer-1a | 26095214 | 26095234 | 144 | -16.51 |
| ADediting_1253200 | chr6_26095235_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-10399-5p | chr6 | 26095229 | 26095235 | 7mer-m8 | 26095215 | 26095236 | 144 | -11.21 |
| ADediting_1253200 | chr6_26095235_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-5089-5p | chr6 | 26095233 | 26095239 | 7mer-m8 | 26095218 | 26095240 | 148 | -14.13 |
| ADediting_1253200 | chr6_26095235_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6504-3p | chr6 | 26095229 | 26095235 | 7mer-m8 | 26095215 | 26095236 | 148 | -14.35 |
| ADediting_1253201 | chr6_26095240_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-5089-5p | chr6 | 26095233 | 26095239 | 7mer-m8 | 26095218 | 26095240 | 148 | -14.13 |
| ADediting_1253201 | chr6_26095240_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-512-3p | chr6 | 26095238 | 26095244 | 7mer-m8 | 26095224 | 26095245 | 149 | -15.51 |
| ADediting_1253201 | chr6_26095240_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6506-5p | chr6 | 26095234 | 26095240 | 7mer-m8 | 26095219 | 26095241 | 144 | -13.78 |
| ADediting_1253202 | chr6_26095256_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6878-3p | chr6 | 26095249 | 26095256 | 8mer-1a | 26095236 | 26095256 | 142 | -14.14 |
| ADediting_1253204 | chr6_26095289_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6843-3p | chr6 | 26095285 | 26095291 | 7mer-m8 | 26095274 | 26095292 | 150 | -20.32 |
| ADediting_1253204 | chr6_26095289_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6848-3p | chr6 | 26095285 | 26095291 | 7mer-m8 | 26095276 | 26095292 | 142 | -15.23 |
| ADediting_1253205 | chr6_26095312_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-193b-5p | chr6 | 26095309 | 26095316 | 8mer-1a | 26095295 | 26095316 | 142 | -13.06 |
| ADediting_1253205 | chr6_26095312_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-3170 | chr6 | 26095310 | 26095316 | 7mer-m8 | 26095293 | 26095317 | 143 | -14.72 |
| ADediting_1253205 | chr6_26095312_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6855-5p | chr6 | 26095310 | 26095316 | 7mer-m8 | 26095291 | 26095317 | 147 | -16.06 |
| ADediting_1253206 | chr6_26095317_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-3170 | chr6 | 26095310 | 26095316 | 7mer-m8 | 26095293 | 26095317 | 143 | -14.72 |
| ADediting_1253206 | chr6_26095317_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6855-5p | chr6 | 26095310 | 26095316 | 7mer-m8 | 26095291 | 26095317 | 147 | -16.06 |
| ADediting_1253206 | chr6_26095317_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6890-5p | chr6 | 26095311 | 26095317 | 7mer-m8 | 26095298 | 26095318 | 142 | -13.82 |
| ADediting_1253211 | chr6_26095342_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4735-5p | chr6 | 26095336 | 26095342 | 7mer-m8 | 26095322 | 26095343 | 140 | -4.28 |
| ADediting_1253212 | chr6_26095368_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-7151-3p | chr6 | 26095361 | 26095367 | 7mer-m8 | 26095348 | 26095368 | 140 | -18.03 |
| ADediting_1253215 | chr6_26095385_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-3614-3p | chr6 | 26095382 | 26095388 | 7mer-m8 | 26095365 | 26095389 | 151 | -17.34 |
| ADediting_1253215 | chr6_26095385_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4297 | chr6 | 26095381 | 26095387 | 7mer-m8 | 26095370 | 26095388 | 141 | -14.78 |
| ADediting_1253215 | chr6_26095385_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-5581-5p | chr6 | 26095381 | 26095387 | 7mer-m8 | 26095366 | 26095388 | 148 | -23.31 |
| ADediting_1253217 | chr6_26095409_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-1206 | chr6 | 26095404 | 26095410 | 7mer-m8 | 26095391 | 26095411 | 145 | -11.84 |
| ADediting_1253218 | chr6_26095410_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-1206 | chr6 | 26095404 | 26095410 | 7mer-m8 | 26095391 | 26095411 | 145 | -11.84 |
| ADediting_1253219 | chr6_26095414_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-1343-3p | chr6 | 26095410 | 26095416 | 7mer-m8 | 26095394 | 26095417 | 150 | -25.37 |
| ADediting_1253219 | chr6_26095414_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6742-3p | chr6 | 26095409 | 26095416 | 8mer-1a | 26095395 | 26095416 | 152 | -20.82 |
| ADediting_1253219 | chr6_26095414_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6783-3p | chr6 | 26095410 | 26095416 | 7mer-m8 | 26095396 | 26095417 | 150 | -20.17 |
| ADediting_1253220 | chr6_26095421_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-3194-3p | chr6 | 26095418 | 26095424 | 7mer-m8 | 26095407 | 26095425 | 153 | -23.95 |
| ADediting_1253220 | chr6_26095421_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-5001-3p | chr6 | 26095416 | 26095422 | 7mer-m8 | 26095399 | 26095423 | 154 | -19.84 |
| ADediting_1253220 | chr6_26095421_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6836-3p | chr6 | 26095414 | 26095420 | 7mer-m8 | 26095401 | 26095421 | 140 | -15.97 |
| ADediting_1253222 | chr6_26096163_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-371b-5p | chr6 | 26096157 | 26096164 | 8mer-1a | 26096143 | 26096164 | 146 | -9.96 |
| ADediting_1253222 | chr6_26096163_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-373-5p | chr6 | 26096157 | 26096164 | 8mer-1a | 26096143 | 26096164 | 142 | -9.74 |
| ADediting_1253222 | chr6_26096163_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-616-5p | chr6 | 26096157 | 26096164 | 8mer-1a | 26096143 | 26096164 | 140 | -9.28 |
| ADediting_1253224 | chr6_26096190_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-32-5p | chr6 | 26096184 | 26096190 | 7mer-m8 | 26096170 | 26096191 | 144 | -12.53 |
| ADediting_1253224 | chr6_26096190_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-363-3p | chr6 | 26096184 | 26096190 | 7mer-m8 | 26096170 | 26096191 | 147 | -16.12 |
| ADediting_1253224 | chr6_26096190_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-92a-3p | chr6 | 26096184 | 26096190 | 7mer-m8 | 26096174 | 26096191 | 155 | -26.92 |
| ADediting_1253225 | chr6_26096227_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-3689a-3p | chr6 | 26096220 | 26096226 | 7mer-m8 | 26096204 | 26096227 | 151 | -22.81 |
| ADediting_1253225 | chr6_26096227_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-3689b-3p | chr6 | 26096220 | 26096226 | 7mer-m8 | 26096204 | 26096227 | 151 | -22.77 |
| ADediting_1253225 | chr6_26096227_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-3689c | chr6 | 26096220 | 26096226 | 7mer-m8 | 26096204 | 26096227 | 151 | -22.77 |
| ADediting_1253225 | chr6_26096227_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-490-3p | chr6 | 26096224 | 26096230 | 7mer-m8 | 26096209 | 26096231 | 146 | -16.15 |
| ADediting_1253225 | chr6_26096227_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6779-5p | chr6 | 26096220 | 26096226 | 7mer-m8 | 26096209 | 26096227 | 148 | -23.13 |
| ADediting_1253225 | chr6_26096227_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6780a-5p | chr6 | 26096220 | 26096226 | 7mer-m8 | 26096202 | 26096227 | 148 | -24.54 |
| ADediting_1253229 | chr6_26096251_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-3929 | chr6 | 26096248 | 26096254 | 7mer-m8 | 26096234 | 26096255 | 152 | -18.17 |
| ADediting_1253229 | chr6_26096251_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4329 | chr6 | 26096245 | 26096251 | 7mer-m8 | 26096234 | 26096252 | 141 | -10.73 |
| ADediting_1253229 | chr6_26096251_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4478 | chr6 | 26096248 | 26096254 | 7mer-m8 | 26096240 | 26096255 | 149 | -25.11 |
| ADediting_1253230 | chr6_26096259_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-12126 | chr6 | 26096255 | 26096262 | 8mer-1a | 26096239 | 26096262 | 147 | -16.24 |
| ADediting_1253230 | chr6_26096259_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-1273h-5p | chr6 | 26096252 | 26096259 | 8mer-1a | 26096239 | 26096259 | 155 | -21.22 |
| ADediting_1253230 | chr6_26096259_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-30b-3p | chr6 | 26096252 | 26096259 | 8mer-1a | 26096238 | 26096259 | 148 | -16.41 |
| ADediting_1253230 | chr6_26096259_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-3689a-3p | chr6 | 26096252 | 26096259 | 8mer-1a | 26096237 | 26096259 | 154 | -19.43 |
| ADediting_1253230 | chr6_26096259_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-3689b-3p | chr6 | 26096252 | 26096259 | 8mer-1a | 26096237 | 26096259 | 154 | -18.98 |
| ADediting_1253230 | chr6_26096259_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-3689c | chr6 | 26096252 | 26096259 | 8mer-1a | 26096237 | 26096259 | 154 | -18.98 |
| ADediting_1253230 | chr6_26096259_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6779-5p | chr6 | 26096252 | 26096259 | 8mer-1a | 26096241 | 26096259 | 148 | -23.21 |
| ADediting_1253230 | chr6_26096259_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-887-5p | chr6 | 26096253 | 26096259 | 7mer-m8 | 26096243 | 26096260 | 150 | -21.51 |
| ADediting_1253231 | chr6_26096260_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-12126 | chr6 | 26096255 | 26096262 | 8mer-1a | 26096239 | 26096262 | 147 | -16.24 |
| ADediting_1253231 | chr6_26096260_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-887-5p | chr6 | 26096253 | 26096259 | 7mer-m8 | 26096243 | 26096260 | 150 | -21.51 |
| ADediting_1253232 | chr6_26096263_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-5690 | chr6 | 26096260 | 26096266 | 7mer-m8 | 26096247 | 26096267 | 145 | -16.74 |
| ADediting_1253238 | chr6_26096317_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-593-3p | chr6 | 26096316 | 26096322 | 7mer-1a | 26096304 | 26096322 | 140 | -19.02 |
| ADediting_1253239 | chr6_26096323_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-10a-5p | chr6 | 26096320 | 26096326 | 7mer-m8 | 26096305 | 26096327 | 145 | -13.67 |
| ADediting_1253239 | chr6_26096323_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-10b-5p | chr6 | 26096320 | 26096326 | 7mer-m8 | 26096305 | 26096327 | 140 | -13.05 |
| ADediting_1253239 | chr6_26096323_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-339-5p | chr6 | 26096319 | 26096325 | 7mer-m8 | 26096302 | 26096326 | 151 | -18.58 |
| ADediting_1253239 | chr6_26096323_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4421 | chr6 | 26096318 | 26096324 | 7mer-m8 | 26096304 | 26096325 | 154 | -16.19 |
| ADediting_1253239 | chr6_26096323_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-5699-3p | chr6 | 26096318 | 26096324 | 7mer-m8 | 26096304 | 26096325 | 153 | -17.34 |
| ADediting_1253239 | chr6_26096323_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6818-3p | chr6 | 26096316 | 26096322 | 7mer-m8 | 26096302 | 26096323 | 140 | -12.56 |
| ADediting_1253241 | chr6_26096395_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-887-5p | chr6 | 26096388 | 26096395 | 8mer-1a | 26096374 | 26096395 | 150 | -16.01 |
| ADediting_1253243 | chr6_26096403_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-216a-5p | chr6 | 26096400 | 26096407 | 8mer-1a | 26096386 | 26096407 | 150 | -16.7 |
| ADediting_1253245 | chr6_26096417_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4284 | chr6 | 26096413 | 26096420 | 8mer-1a | 26096403 | 26096420 | 151 | -19.56 |
| ADediting_1583320 | chr6_26095406_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-1206 | chr6 | 26095404 | 26095410 | 7mer-m8 | 26095391 | 26095411 | 145 | -11.84 |
| ADediting_1583321 | chr6_26095434_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4284 | chr6 | 26095430 | 26095436 | 7mer-m8 | 26095420 | 26095437 | 144 | -12.71 |
| ADediting_1583322 | chr6_26095439_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4638-5p | chr6 | 26095433 | 26095439 | 7mer-m8 | 26095421 | 26095440 | 146 | -23.42 |
| ADediting_1583323 | chr6_26095471_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-3664-5p | chr6 | 26095468 | 26095474 | 7mer-m8 | 26095454 | 26095475 | 148 | -14.2 |
| ADediting_1583323 | chr6_26095471_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6773-3p | chr6 | 26095465 | 26095472 | 8mer-1a | 26095451 | 26095472 | 146 | -16.39 |
| ADediting_1583324 | chr6_26096394_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-30b-3p | chr6 | 26096387 | 26096394 | 8mer-1a | 26096373 | 26096394 | 151 | -17.42 |
| ADediting_1583324 | chr6_26096394_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-3689a-3p | chr6 | 26096387 | 26096394 | 8mer-1a | 26096374 | 26096394 | 143 | -19.8 |
| ADediting_1583324 | chr6_26096394_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-3689b-3p | chr6 | 26096387 | 26096394 | 8mer-1a | 26096374 | 26096394 | 143 | -19.85 |
| ADediting_1583324 | chr6_26096394_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-3689c | chr6 | 26096387 | 26096394 | 8mer-1a | 26096374 | 26096394 | 143 | -19.85 |
| ADediting_1583324 | chr6_26096394_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-6779-5p | chr6 | 26096387 | 26096394 | 8mer-1a | 26096376 | 26096394 | 144 | -22.9 |
| ADediting_1583324 | chr6_26096394_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-887-5p | chr6 | 26096388 | 26096395 | 8mer-1a | 26096374 | 26096395 | 150 | -16.01 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-5688 | chr6 | 26095553 | 26095560 | 8mer-1a | 26095540 | 26095560 | 141 | -14.39 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000010704.18 | ENST00000317896.11 | HFE-202 | hsa-miR-4477b | chr6 | 26094378 | 26094385 | 8mer-1a | 26094364 | 26094385 | 147 | -10.43 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000010704.18 | ENST00000349999.8 | HFE-204 | hsa-miR-4477b | chr6 | 26094378 | 26094385 | 8mer-1a | 26094364 | 26094385 | 147 | -10.43 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000010704.18 | ENST00000352392.8 | HFE-205 | hsa-miR-4477b | chr6 | 26094378 | 26094385 | 8mer-1a | 26094364 | 26094385 | 147 | -10.43 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4477b | chr6 | 26094378 | 26094385 | 8mer-1a | 26094364 | 26094385 | 147 | -10.43 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-641 | chr6 | 26095680 | 26095686 | 7mer-1a | 26095664 | 26095686 | 140 | -25.63 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4775 | chr6 | 26097384 | 26097391 | 8mer-1a | 26097370 | 26097391 | 147 | -7.36 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-5585-3p | chr6 | 26097430 | 26097436 | 7mer-m8 | 26097417 | 26097437 | 150 | -15.75 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000010704.18 | ENST00000317896.11 | HFE-202 | hsa-miR-589-3p | chr6 | 26095043 | 26095050 | 8mer-1a | 26095027 | 26095050 | 145 | -18.02 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-589-3p | chr6 | 26095043 | 26095050 | 8mer-1a | 26095027 | 26095050 | 145 | -18.02 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000010704.18 | ENST00000317896.11 | HFE-202 | hsa-miR-4477b | chr6 | 26094562 | 26094569 | 8mer-1a | 26094548 | 26094569 | 143 | -6.67 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000010704.18 | ENST00000349999.8 | HFE-204 | hsa-miR-4477b | chr6 | 26094562 | 26094569 | 8mer-1a | 26094548 | 26094569 | 143 | -6.67 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4477b | chr6 | 26094562 | 26094569 | 8mer-1a | 26094548 | 26094569 | 143 | -6.67 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000010704.18 | ENST00000485729.1 | HFE-212 | hsa-miR-4477b | chr6 | 26094562 | 26094569 | 8mer-1a | 26094548 | 26094569 | 143 | -6.67 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000010704.18 | ENST00000317896.11 | HFE-202 | hsa-miR-4477b | chr6 | 26094562 | 26094569 | 8mer-1a | 26094548 | 26094569 | 143 | -6.67 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000010704.18 | ENST00000349999.8 | HFE-204 | hsa-miR-4477b | chr6 | 26094562 | 26094569 | 8mer-1a | 26094548 | 26094569 | 143 | -6.67 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4477b | chr6 | 26094562 | 26094569 | 8mer-1a | 26094548 | 26094569 | 143 | -6.67 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000010704.18 | ENST00000485729.1 | HFE-212 | hsa-miR-4477b | chr6 | 26094562 | 26094569 | 8mer-1a | 26094548 | 26094569 | 143 | -6.67 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000010704.18 | ENST00000317896.11 | HFE-202 | hsa-miR-4775 | chr6 | 26095056 | 26095062 | 7mer-m8 | 26095042 | 26095063 | 153 | -8.06 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000010704.18 | ENST00000357618.9 | HFE-207 | hsa-miR-4775 | chr6 | 26095056 | 26095062 | 7mer-m8 | 26095042 | 26095063 | 153 | -8.06 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for HFE |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000349999.8 | protein_coding |  |  |
| ENST00000317896.11 | protein_coding |  |  |
| ENST00000357618.9 | protein_coding |  |  |
| ENST00000485729.1 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1253197 | ENST00000349999.8 | chr6_26094800_+ | 1517 | -581.00 | -577.70 | -581.00 |
| ADediting_1253197 | ENST00000317896.11 | chr6_26094800_+ | 1505 | -614.20 | -610.90 | -614.20 |
| ADediting_1253197 | ENST00000357618.9 | chr6_26094800_+ | 1743 | -1801.10 | -1797.80 | -1846.80 |
| ADediting_1253198 | ENST00000357618.9 | chr6_26095226_+ | 2169 | -1797.40 | -1797.80 | -1846.80 |
| ADediting_1253199 | ENST00000357618.9 | chr6_26095234_+ | 2177 | -1797.90 | -1797.80 | -1846.80 |
| ADediting_1253200 | ENST00000357618.9 | chr6_26095235_+ | 2178 | -1797.80 | -1797.80 | -1846.80 |
| ADediting_1253201 | ENST00000357618.9 | chr6_26095240_+ | 2183 | -1797.10 | -1797.80 | -1846.80 |
| ADediting_1253202 | ENST00000357618.9 | chr6_26095256_+ | 2199 | -1803.40 | -1797.80 | -1846.80 |
| ADediting_1253203 | ENST00000357618.9 | chr6_26095258_+ | 2201 | -1804.00 | -1797.80 | -1846.80 |
| ADediting_1253204 | ENST00000357618.9 | chr6_26095289_+ | 2232 | -1797.20 | -1797.80 | -1846.80 |
| ADediting_1253205 | ENST00000357618.9 | chr6_26095312_+ | 2255 | -1797.80 | -1797.80 | -1846.80 |
| ADediting_1253206 | ENST00000357618.9 | chr6_26095317_+ | 2260 | -1801.20 | -1797.80 | -1846.80 |
| ADediting_1253207 | ENST00000357618.9 | chr6_26095323_+ | 2266 | -1797.50 | -1797.80 | -1846.80 |
| ADediting_1253208 | ENST00000357618.9 | chr6_26095324_+ | 2267 | -1800.40 | -1797.80 | -1846.80 |
| ADediting_1253209 | ENST00000357618.9 | chr6_26095328_+ | 2271 | -1797.90 | -1797.80 | -1846.80 |
| ADediting_1253210 | ENST00000357618.9 | chr6_26095329_+ | 2272 | -1797.90 | -1797.80 | -1846.80 |
| ADediting_1253211 | ENST00000357618.9 | chr6_26095342_+ | 2285 | -1797.50 | -1797.80 | -1846.80 |
| ADediting_1253212 | ENST00000357618.9 | chr6_26095368_+ | 2311 | -1797.40 | -1797.80 | -1846.80 |
| ADediting_1253213 | ENST00000357618.9 | chr6_26095374_+ | 2317 | -1797.10 | -1797.80 | -1846.80 |
| ADediting_1253214 | ENST00000357618.9 | chr6_26095378_+ | 2321 | -1797.80 | -1797.80 | -1846.80 |
| ADediting_1253215 | ENST00000357618.9 | chr6_26095385_+ | 2328 | -1797.80 | -1797.80 | -1846.80 |
| ADediting_1253216 | ENST00000357618.9 | chr6_26095401_+ | 2344 | -1797.80 | -1797.80 | -1846.80 |
| ADediting_1583320 | ENST00000357618.9 | chr6_26095406_+ | 2349 | -1797.80 | -1797.80 | -1846.80 |
| ADediting_1253217 | ENST00000357618.9 | chr6_26095409_+ | 2352 | -1797.30 | -1797.80 | -1846.80 |
| ADediting_1253218 | ENST00000357618.9 | chr6_26095410_+ | 2353 | -1797.80 | -1797.80 | -1846.80 |
| ADediting_1253219 | ENST00000357618.9 | chr6_26095414_+ | 2357 | -1801.70 | -1797.80 | -1846.80 |
| ADediting_1253220 | ENST00000357618.9 | chr6_26095421_+ | 2364 | -1797.10 | -1797.80 | -1846.80 |
| ADediting_1583321 | ENST00000357618.9 | chr6_26095434_+ | 2377 | -1796.90 | -1797.80 | -1846.80 |
| ADediting_1583322 | ENST00000357618.9 | chr6_26095439_+ | 2382 | -1796.90 | -1797.80 | -1846.80 |
| ADediting_1253221 | ENST00000357618.9 | chr6_26095464_+ | 2407 | -1804.40 | -1797.80 | -1846.80 |
| ADediting_1583323 | ENST00000357618.9 | chr6_26095471_+ | 2414 | -1797.50 | -1797.80 | -1846.80 |
| ADediting_1253222 | ENST00000357618.9 | chr6_26096163_+ | 3106 | -1797.30 | -1797.80 | -1846.80 |
| ADediting_1253223 | ENST00000357618.9 | chr6_26096170_+ | 3113 | -1803.70 | -1797.80 | -1846.80 |
| ADediting_1253224 | ENST00000357618.9 | chr6_26096190_+ | 3133 | -1804.00 | -1797.80 | -1846.80 |
| ADediting_1253225 | ENST00000357618.9 | chr6_26096227_+ | 3170 | -1801.70 | -1797.80 | -1846.80 |
| ADediting_1253226 | ENST00000357618.9 | chr6_26096233_+ | 3176 | -1797.70 | -1797.80 | -1846.80 |
| ADediting_1253227 | ENST00000357618.9 | chr6_26096234_+ | 3177 | -1797.80 | -1797.80 | -1846.80 |
| ADediting_1253228 | ENST00000357618.9 | chr6_26096238_+ | 3181 | -1798.10 | -1797.80 | -1846.80 |
| ADediting_1253229 | ENST00000357618.9 | chr6_26096251_+ | 3194 | -1797.10 | -1797.80 | -1846.80 |
| ADediting_1253230 | ENST00000357618.9 | chr6_26096259_+ | 3202 | -1803.80 | -1797.80 | -1846.80 |
| ADediting_1253231 | ENST00000357618.9 | chr6_26096260_+ | 3203 | -1797.70 | -1797.80 | -1846.80 |
| ADediting_1253232 | ENST00000357618.9 | chr6_26096263_+ | 3206 | -1797.50 | -1797.80 | -1846.80 |
| ADediting_1253233 | ENST00000357618.9 | chr6_26096273_+ | 3216 | -1797.80 | -1797.80 | -1846.80 |
| ADediting_1253234 | ENST00000357618.9 | chr6_26096275_+ | 3218 | -1797.10 | -1797.80 | -1846.80 |
| ADediting_1253235 | ENST00000357618.9 | chr6_26096299_+ | 3242 | -1797.90 | -1797.80 | -1846.80 |
| ADediting_1253236 | ENST00000357618.9 | chr6_26096308_+ | 3251 | -1797.80 | -1797.80 | -1846.80 |
| ADediting_1253237 | ENST00000357618.9 | chr6_26096314_+ | 3257 | -1797.50 | -1797.80 | -1846.80 |
| ADediting_1253238 | ENST00000357618.9 | chr6_26096317_+ | 3260 | -1797.50 | -1797.80 | -1846.80 |
| ADediting_1253239 | ENST00000357618.9 | chr6_26096323_+ | 3266 | -1801.60 | -1797.80 | -1846.80 |
| ADediting_1253240 | ENST00000357618.9 | chr6_26096365_+ | 3308 | -1797.20 | -1797.80 | -1846.80 |
| ADediting_1583324 | ENST00000357618.9 | chr6_26096394_+ | 3337 | -1797.50 | -1797.80 | -1846.80 |
| ADediting_1253241 | ENST00000357618.9 | chr6_26096395_+ | 3338 | -1797.90 | -1797.80 | -1846.80 |
| ADediting_1253242 | ENST00000357618.9 | chr6_26096396_+ | 3339 | -1797.50 | -1797.80 | -1846.80 |
| ADediting_1253243 | ENST00000357618.9 | chr6_26096403_+ | 3346 | -1804.70 | -1797.80 | -1846.80 |
| ADediting_1253244 | ENST00000357618.9 | chr6_26096408_+ | 3351 | -1797.80 | -1797.80 | -1846.80 |
| ADediting_1253245 | ENST00000357618.9 | chr6_26096417_+ | 3360 | -1796.90 | -1797.80 | -1846.80 |
| ADediting_1253197 | ENST00000485729.1 | chr6_26094800_+ | 557 | -221.90 | -218.60 | -221.90 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
Top |
Relation with ADAR for HFE |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_1253198 | chr6_26095226_+ | 0.726923971807906 | -0.0199128530838274 | 0.125509651350464 | -0.0872011381569294 | 3.94467005332565e-08 | 0.305731991482881 |
| DLPFC | ADediting_1253199 | chr6_26095234_+ | 0.527637192742784 | 0.0360072590066974 | 0.283495640411919 | -0.0611037999250783 | 4.61715476946267e-10 | 0.344433819372984 |
| DLPFC | ADediting_1253200 | chr6_26095235_+ | 0.820466301732709 | 0.0129413652319976 | 0.125569649360974 | -0.0871873536811359 | 1.92663760581058e-09 | 0.332584767752518 |
| DLPFC | ADediting_1253202 | chr6_26095256_+ | 0.409089222901745 | 0.0470492025247635 | 0.120287333841225 | -0.0884210652509282 | 3.15870044143719e-19 | 0.479487416002668 |
| DLPFC | ADediting_1253203 | chr6_26095258_+ | 0.56197326573086 | 0.0330614014774708 | 0.163570479367423 | -0.0793220599860625 | 1.06545013086354e-16 | 0.447869110672431 |
| DLPFC | ADediting_1253207 | chr6_26095323_+ | 0.168861280741887 | 0.0783406074613181 | 0.316123597056751 | -0.0571199057330895 | 5.53710955181821e-17 | 0.45159227246333 |
| DLPFC | ADediting_1253219 | chr6_26095414_+ | 0.770910271048004 | -0.0166041005562169 | 0.0690852214410941 | -0.103388442613738 | 5.66869487537462e-14 | 0.409631128292181 |
| DLPFC | ADediting_1253225 | chr6_26096227_+ | 0.271154490716815 | -0.0626907232596519 | 0.00396506567169558 | -0.163186719152785 | 1.62001047224131e-11 | 0.370420097115922 |
| DLPFC | ADediting_1253227 | chr6_26096234_+ | 0.226239371173185 | -0.0689259114591118 | 0.00501612885952287 | -0.158997158830288 | 7.71028719144466e-12 | 0.375875812721458 |
| DLPFC | ADediting_1253228 | chr6_26096238_+ | 0.596561187340568 | -0.0301802528070166 | 0.0590610499087459 | -0.107340014973697 | 2.48126665101088e-08 | 0.310031985844353 |
| DLPFC | ADediting_1253229 | chr6_26096251_+ | 0.231870235186982 | -0.0680992163151087 | 0.00938927692510103 | -0.147319973966166 | 3.49421764929365e-08 | 0.306863365872772 |
| DLPFC | ADediting_1253230 | chr6_26096259_+ | 0.167672776846636 | -0.0785590519991147 | 0.00653172196015419 | -0.1541736417921 | 3.88610095726421e-11 | 0.363856256899946 |
| DLPFC | ADediting_1253232 | chr6_26096263_+ | 0.326315673029356 | -0.0559312731222002 | 0.00846601504024359 | -0.149302556532545 | 5.59071518750661e-08 | 0.302451029030094 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 1.13683789641379e-09 | 0.337018829109673 | 0.0709453839287017 | 0.1027075957967 | 3.91197551149343e-73 | 0.809257701790228 |
| AC | 8.36328340735315e-42 | 0.723537106635695 | 3.35043259301163e-20 | 0.538514749789314 | 1.08485945764435e-35 | 0.682987700110171 |
| PCC | 2.78358222444318e-05 | 0.298241274900802 | 0.0178485369230644 | 0.171252420287131 | 1.04065764010869e-07 | 0.373345682003309 |
| CER | 0.000306982225891247 | 0.290740918401447 | 0.535570324412705 | 0.0509775793890402 | 2.35223544889956e-11 | 0.511060903980532 |
| TCX | 0.00244947520114215 | 0.245612948167774 | 0.0308472687305723 | -0.176375718312027 | 2.56780066029316e-11 | 0.510218589364992 |
| FP | 1.10111976375932e-05 | 0.322920222579098 | 0.00345795474078419 | 0.218040670823703 | 2.07340844434057e-08 | 0.40488898237867 |
| IFG | 0.25549845899282 | 0.236277158296167 | 0.333889971170191 | 0.201588345848249 | 0.0006199434302973 | 0.636793730860369 |
| PG | 1.97248709636488e-25 | 0.668340286008686 | 2.98666854052681e-10 | 0.440979833704343 | 0.0409903983266496 | 0.150008302177992 |
| STG | 0.425729630791572 | 0.0880579370538543 | 0.190314740287445 | -0.144307426697944 | 1.18343558121885e-05 | 0.458001187877114 |
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Relation with AD stages for HFE |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| TCX | ADediting_1253219 | chr6_26095414_+ | 0.00084275249608139 | 0.319495908969148 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| TCX | 3.51132861378361e-08 | 0.50448187201005 |
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RelatedDrugs for HFE |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for HFE |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| HFE | C0392514 | Hereditary hemochromatosis | 30 | CTD_human;UNIPROT |
| HFE | C3469186 | HEMOCHROMATOSIS, TYPE 1 | 16 | UNIPROT |
| HFE | C0018995 | Hemochromatosis | 14 | CTD_human |
| HFE | C0002395 | Alzheimer's Disease | 2 | CTD_human |
| HFE | C0011265 | Presenile dementia | 2 | CTD_human |
| HFE | C0276496 | Familial Alzheimer Disease (FAD) | 2 | CTD_human |
| HFE | C0494463 | Alzheimer Disease, Late Onset | 2 | CTD_human |
| HFE | C0546126 | Acute Confusional Senile Dementia | 2 | CTD_human |
| HFE | C0750900 | Alzheimer's Disease, Focal Onset | 2 | CTD_human |
| HFE | C0750901 | Alzheimer Disease, Early Onset | 2 | CTD_human |
| HFE | C0005612 | Birth Weight | 1 | CTD_human |
| HFE | C0019196 | Hepatitis C | 1 | CTD_human |
| HFE | C0020445 | Hypercholesterolemia, Familial | 1 | GENOMICS_ENGLAND |
| HFE | C0023176 | Lead Poisoning | 1 | CTD_human |
| HFE | C0030567 | Parkinson Disease | 1 | CTD_human |
| HFE | C0036337 | Schizoaffective Disorder | 1 | PSYGENET |
| HFE | C0036341 | Schizophrenia | 1 | PSYGENET |
| HFE | C0085762 | Alcohol abuse | 1 | PSYGENET |
| HFE | C1510586 | Autism Spectrum Disorders | 1 | CTD_human |
| HFE | C2713368 | Hematopoetic Myelodysplasia | 1 | CTD_human |
| HFE | C3463824 | MYELODYSPLASTIC SYNDROME | 1 | CTD_human |
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