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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for HAGH |
 Gene summary |
| Gene information | Gene symbol | HAGH | Gene ID | 3029 |
| Gene name | hydroxyacylglutathione hydrolase | |
| Synonyms | GLO2|GLX2|GLXII|HAGH1 | |
| Cytomap | 16p13.3 | |
| Type of gene | protein-coding | |
| Description | hydroxyacylglutathione hydrolase, mitochondrialglyoxalase IIhydroxyacylglutathione hydroxylase | |
| Modification date | 20200313 | |
| UniProtAcc | Q16775, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| HAGH | GO:0006750 | glutathione biosynthetic process | 8550579 |
Top |
RNA A-to-I events for HAGH |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_519997(1796374, -), ADediting_519998(1797567, -), ADediting_519999(1797605, -), ADediting_520000(1797630, -), ADediting_520001(1797644, -), ADediting_520002(1797715, -), ADediting_520003(1798381, -), ADediting_520004(1798455, -), ADediting_520005(1798472, -), ADediting_520006(1798475, -), ADediting_520007(1798516, -), ADediting_520008(1798530, -), ADediting_520009(1798538, -), ADediting_520010(1798543, -), ADediting_520011(1798555, -), ADediting_520012(1800179, -), ADediting_520013(1800269, -), ADediting_520014(1801192, -), ADediting_520015(1801224, -), ADediting_520016(1801225, -), ADediting_520017(1801281, -), ADediting_520018(1801285, -), ADediting_520019(1801289, -), ADediting_520020(1801295, -), ADediting_520021(1801324, -), ADediting_520022(1801331, -), ADediting_520023(1801340, -), ADediting_520024(1801351, -), ADediting_520025(1801588, -), ADediting_520026(1801589, -), ADediting_520027(1801623, -), ADediting_520028(1802160, -), ADediting_520029(1802161, -), ADediting_520030(1802170, -), ADediting_520031(1802176, -), ADediting_520032(1802187, -), ADediting_520033(1802208, -), ADediting_520034(1802239, -), ADediting_520035(1802256, -), ADediting_520036(1802257, -), ADediting_520037(1802273, -), ADediting_520038(1802281, -), ADediting_520039(1802283, -), ADediting_520040(1802293, -), ADediting_520041(1802296, -), ADediting_520042(1802305, -), ADediting_520043(1802306, -), ADediting_520044(1802311, -), ADediting_520045(1802325, -), ADediting_520046(1802335, -), ADediting_520047(1802340, -), ADediting_520048(1802350, -), ADediting_520049(1802353, -), ADediting_520050(1802375, -), ADediting_520051(1802917, -), ADediting_520052(1802943, -), ADediting_520053(1802947, -), ADediting_520054(1803223, -), ADediting_520055(1803249, -), ADediting_520056(1803252, -), ADediting_520057(1803253, -), ADediting_520058(1803267, -), ADediting_520059(1803302, -), ADediting_520060(1803619, -), ADediting_520061(1803623, -), ADediting_520062(1803667, -), ADediting_520063(1803850, -), ADediting_520064(1804926, -), ADediting_520065(1804927, -), ADediting_520066(1805512, -), ADediting_520067(1805517, -), ADediting_520068(1806082, -), ADediting_520069(1806183, -), ADediting_520070(1806225, -), ADediting_520071(1806251, -), ADediting_520072(1806254, -), ADediting_520073(1806256, -), ADediting_520074(1806289, -), ADediting_520075(1806291, -), ADediting_520076(1806333, -), ADediting_520077(1806360, -), ADediting_520078(1806622, -), ADediting_520079(1806655, -), ADediting_520080(1806675, -), ADediting_520081(1806683, -), ADediting_520082(1806684, -), ADediting_520083(1806695, -), ADediting_520084(1806715, -), ADediting_520085(1806725, -), ADediting_520086(1806751, -), ADediting_520087(1806769, -), ADediting_520088(1806824, -), ADediting_520089(1806960, -), ADediting_520090(1807025, -), ADediting_520091(1807102, -), ADediting_520092(1807103, -), ADediting_520093(1807283, -), ADediting_520094(1807295, -), ADediting_520095(1807296, -), ADediting_520096(1807310, -), ADediting_520097(1807314, -), ADediting_520098(1807348, -), ADediting_520099(1807374, -), ADediting_520100(1807377, -), ADediting_520101(1807406, -), ADediting_520102(1807409, -), ADediting_520103(1807417, -), ADediting_520104(1807419, -), ADediting_520105(1807429, -), ADediting_520106(1807441, -), ADediting_520107(1807458, -), ADediting_520108(1807459, -), ADediting_520109(1807479, -), ADediting_520110(1807484, -), ADediting_520111(1807494, -), ADediting_520112(1807535, -), ADediting_520113(1808205, -), ADediting_520114(1808219, -), ADediting_520115(1808223, -), ADediting_520116(1808236, -), ADediting_520117(1808246, -), ADediting_520118(1808439, -), ADediting_520119(1808447, -), ADediting_520120(1808503, -), ADediting_520121(1810070, -), ADediting_520122(1810118, -), ADediting_520123(1810121, -), ADediting_520124(1815798, -), ADediting_520125(1815856, -), ADediting_520126(1815897, -), ADediting_520127(1816008, -), ADediting_520128(1816009, -), ADediting_520129(1816033, -), ADediting_520130(1816073, -), ADediting_520131(1816121, -), ADediting_520132(1816157, -), ADediting_520133(1816168, -), ADediting_520134(1818063, -), ADediting_520135(1823197, -), ADediting_520136(1823211, -), ADediting_520137(1823259, -), ADediting_520138(1823260, -), ADediting_520139(1823379, -), ADediting_520140(1823392, -), ADediting_520141(1823400, -), ADediting_520142(1823406, -), ADediting_520143(1823432, -), ADediting_520144(1823546, -), ADediting_520145(1823621, -), ADediting_520146(1823643, -), ADediting_520147(1824181, -), ADediting_520148(1825074, -), ADediting_520149(1825075, -), ADediting_520150(1825145, -), ADediting_520151(1825196, -), ADediting_520152(1825206, -), ADediting_520153(1825235, -), ADediting_520154(1825255, -), ADediting_520155(1825272, -), ADediting_520156(1825616, -), ADediting_520157(1825666, -), ADediting_520158(1825689, -), ADediting_520159(1825712, -), ADediting_520160(1825792, -), ADediting_520161(1825841, -), ADediting_520162(1825863, -), ADediting_1541180(1801190, -), ADediting_1541181(1801336, -), ADediting_1541182(1806257, -), ADediting_1541183(1806343, -), ADediting_1541184(1807275, -), ADediting_1541185(1807454, -), ADediting_1541186(1815853, -), ADediting_1541187(1815975, -), ADediting_1541188(1815988, -), |
Top |
RNA editing positional annotations for HAGH using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_519997 | chr16_1796374_- | intronic |
| ADediting_519998 | chr16_1797567_- | intronic |
| ADediting_519999 | chr16_1797605_- | intronic |
| ADediting_520000 | chr16_1797630_- | intronic |
| ADediting_520001 | chr16_1797644_- | intronic |
| ADediting_520002 | chr16_1797715_- | intronic |
| ADediting_520003 | chr16_1798381_- | intronic |
| ADediting_520004 | chr16_1798455_- | intronic |
| ADediting_520005 | chr16_1798472_- | intronic |
| ADediting_520006 | chr16_1798475_- | intronic |
| ADediting_520007 | chr16_1798516_- | intronic |
| ADediting_520008 | chr16_1798530_- | intronic |
| ADediting_520009 | chr16_1798538_- | intronic |
| ADediting_520010 | chr16_1798543_- | intronic |
| ADediting_520011 | chr16_1798555_- | intronic |
| ADediting_520012 | chr16_1800179_- | intronic |
| ADediting_520013 | chr16_1800269_- | intronic |
| ADediting_520014 | chr16_1801192_- | intronic |
| ADediting_520015 | chr16_1801224_- | intronic |
| ADediting_520016 | chr16_1801225_- | intronic |
| ADediting_520017 | chr16_1801281_- | intronic |
| ADediting_520018 | chr16_1801285_- | intronic |
| ADediting_520019 | chr16_1801289_- | intronic |
| ADediting_520020 | chr16_1801295_- | intronic |
| ADediting_520021 | chr16_1801324_- | intronic |
| ADediting_520022 | chr16_1801331_- | intronic |
| ADediting_520023 | chr16_1801340_- | intronic |
| ADediting_520024 | chr16_1801351_- | intronic |
| ADediting_520025 | chr16_1801588_- | intronic |
| ADediting_520026 | chr16_1801589_- | intronic |
| ADediting_520027 | chr16_1801623_- | intronic |
| ADediting_520028 | chr16_1802160_- | intronic |
| ADediting_520029 | chr16_1802161_- | intronic |
| ADediting_520030 | chr16_1802170_- | intronic |
| ADediting_520031 | chr16_1802176_- | intronic |
| ADediting_520032 | chr16_1802187_- | intronic |
| ADediting_520033 | chr16_1802208_- | intronic |
| ADediting_520034 | chr16_1802239_- | intronic |
| ADediting_520035 | chr16_1802256_- | intronic |
| ADediting_520036 | chr16_1802257_- | intronic |
| ADediting_520037 | chr16_1802273_- | intronic |
| ADediting_520038 | chr16_1802281_- | intronic |
| ADediting_520039 | chr16_1802283_- | intronic |
| ADediting_520040 | chr16_1802293_- | intronic |
| ADediting_520041 | chr16_1802296_- | intronic |
| ADediting_520042 | chr16_1802305_- | intronic |
| ADediting_520043 | chr16_1802306_- | intronic |
| ADediting_520044 | chr16_1802311_- | intronic |
| ADediting_520045 | chr16_1802325_- | intronic |
| ADediting_520046 | chr16_1802335_- | intronic |
| ADediting_520047 | chr16_1802340_- | intronic |
| ADediting_520048 | chr16_1802350_- | intronic |
| ADediting_520049 | chr16_1802353_- | intronic |
| ADediting_520050 | chr16_1802375_- | intronic |
| ADediting_520051 | chr16_1802917_- | intronic |
| ADediting_520052 | chr16_1802943_- | intronic |
| ADediting_520053 | chr16_1802947_- | intronic |
| ADediting_520054 | chr16_1803223_- | intronic |
| ADediting_520055 | chr16_1803249_- | intronic |
| ADediting_520056 | chr16_1803252_- | intronic |
| ADediting_520057 | chr16_1803253_- | intronic |
| ADediting_520058 | chr16_1803267_- | intronic |
| ADediting_520059 | chr16_1803302_- | intronic |
| ADediting_520060 | chr16_1803619_- | intronic |
| ADediting_520061 | chr16_1803623_- | intronic |
| ADediting_520062 | chr16_1803667_- | intronic |
| ADediting_520063 | chr16_1803850_- | intronic |
| ADediting_520064 | chr16_1804926_- | intronic |
| ADediting_520065 | chr16_1804927_- | intronic |
| ADediting_520066 | chr16_1805512_- | intronic |
| ADediting_520067 | chr16_1805517_- | intronic |
| ADediting_520068 | chr16_1806082_- | intronic |
| ADediting_520069 | chr16_1806183_- | intronic |
| ADediting_520070 | chr16_1806225_- | intronic |
| ADediting_520071 | chr16_1806251_- | intronic |
| ADediting_520072 | chr16_1806254_- | intronic |
| ADediting_520073 | chr16_1806256_- | intronic |
| ADediting_520074 | chr16_1806289_- | intronic |
| ADediting_520075 | chr16_1806291_- | intronic |
| ADediting_520076 | chr16_1806333_- | intronic |
| ADediting_520077 | chr16_1806360_- | intronic |
| ADediting_520078 | chr16_1806622_- | intronic |
| ADediting_520079 | chr16_1806655_- | intronic |
| ADediting_520080 | chr16_1806675_- | intronic |
| ADediting_520081 | chr16_1806683_- | intronic |
| ADediting_520082 | chr16_1806684_- | intronic |
| ADediting_520083 | chr16_1806695_- | intronic |
| ADediting_520084 | chr16_1806715_- | intronic |
| ADediting_520085 | chr16_1806725_- | intronic |
| ADediting_520086 | chr16_1806751_- | intronic |
| ADediting_520087 | chr16_1806769_- | intronic |
| ADediting_520088 | chr16_1806824_- | intronic |
| ADediting_520089 | chr16_1806960_- | intronic |
| ADediting_520090 | chr16_1807025_- | intronic |
| ADediting_520091 | chr16_1807102_- | intronic |
| ADediting_520092 | chr16_1807103_- | intronic |
| ADediting_520093 | chr16_1807283_- | intronic |
| ADediting_520094 | chr16_1807295_- | intronic |
| ADediting_520095 | chr16_1807296_- | intronic |
| ADediting_520096 | chr16_1807310_- | intronic |
| ADediting_520097 | chr16_1807314_- | intronic |
| ADediting_520098 | chr16_1807348_- | intronic |
| ADediting_520099 | chr16_1807374_- | intronic |
| ADediting_520100 | chr16_1807377_- | intronic |
| ADediting_520101 | chr16_1807406_- | intronic |
| ADediting_520102 | chr16_1807409_- | intronic |
| ADediting_520103 | chr16_1807417_- | intronic |
| ADediting_520104 | chr16_1807419_- | intronic |
| ADediting_520105 | chr16_1807429_- | intronic |
| ADediting_520106 | chr16_1807441_- | intronic |
| ADediting_520107 | chr16_1807458_- | intronic |
| ADediting_520108 | chr16_1807459_- | intronic |
| ADediting_520109 | chr16_1807479_- | intronic |
| ADediting_520110 | chr16_1807484_- | intronic |
| ADediting_520111 | chr16_1807494_- | intronic |
| ADediting_520112 | chr16_1807535_- | intronic |
| ADediting_520113 | chr16_1808205_- | UTR3 |
| ADediting_520114 | chr16_1808219_- | UTR3 |
| ADediting_520115 | chr16_1808223_- | UTR3 |
| ADediting_520116 | chr16_1808236_- | UTR3 |
| ADediting_520117 | chr16_1808246_- | UTR3 |
| ADediting_520118 | chr16_1808439_- | UTR3 |
| ADediting_520119 | chr16_1808447_- | UTR3 |
| ADediting_520120 | chr16_1808503_- | UTR3 |
| ADediting_520121 | chr16_1810070_- | intronic |
| ADediting_520122 | chr16_1810118_- | intronic |
| ADediting_520123 | chr16_1810121_- | intronic |
| ADediting_520124 | chr16_1815798_- | intronic |
| ADediting_520125 | chr16_1815856_- | intronic |
| ADediting_520126 | chr16_1815897_- | intronic |
| ADediting_520127 | chr16_1816008_- | intronic |
| ADediting_520128 | chr16_1816009_- | intronic |
| ADediting_520129 | chr16_1816033_- | intronic |
| ADediting_520130 | chr16_1816073_- | intronic |
| ADediting_520131 | chr16_1816121_- | intronic |
| ADediting_520132 | chr16_1816157_- | intronic |
| ADediting_520133 | chr16_1816168_- | intronic |
| ADediting_520134 | chr16_1818063_- | intronic |
| ADediting_520135 | chr16_1823197_- | intronic |
| ADediting_520136 | chr16_1823211_- | intronic |
| ADediting_520137 | chr16_1823259_- | intronic |
| ADediting_520138 | chr16_1823260_- | intronic |
| ADediting_520139 | chr16_1823379_- | intronic |
| ADediting_520140 | chr16_1823392_- | intronic |
| ADediting_520141 | chr16_1823400_- | intronic |
| ADediting_520142 | chr16_1823406_- | intronic |
| ADediting_520143 | chr16_1823432_- | intronic |
| ADediting_520144 | chr16_1823546_- | intronic |
| ADediting_520145 | chr16_1823621_- | intronic |
| ADediting_520146 | chr16_1823643_- | intronic |
| ADediting_520147 | chr16_1824181_- | intronic |
| ADediting_520148 | chr16_1825074_- | intronic |
| ADediting_520149 | chr16_1825075_- | intronic |
| ADediting_520150 | chr16_1825145_- | intronic |
| ADediting_520151 | chr16_1825196_- | intronic |
| ADediting_520152 | chr16_1825206_- | intronic |
| ADediting_520153 | chr16_1825235_- | intronic |
| ADediting_520154 | chr16_1825255_- | intronic |
| ADediting_520155 | chr16_1825272_- | intronic |
| ADediting_520156 | chr16_1825616_- | intronic |
| ADediting_520157 | chr16_1825666_- | intronic |
| ADediting_520158 | chr16_1825689_- | intronic |
| ADediting_520159 | chr16_1825712_- | intronic |
| ADediting_520160 | chr16_1825792_- | intronic |
| ADediting_520161 | chr16_1825841_- | intronic |
| ADediting_520162 | chr16_1825863_- | intronic |
| ADediting_1541180 | chr16_1801190_- | intronic |
| ADediting_1541181 | chr16_1801336_- | intronic |
| ADediting_1541182 | chr16_1806257_- | intronic |
| ADediting_1541183 | chr16_1806343_- | intronic |
| ADediting_1541184 | chr16_1807275_- | intronic |
| ADediting_1541185 | chr16_1807454_- | intronic |
| ADediting_1541186 | chr16_1815853_- | intronic |
| ADediting_1541187 | chr16_1815975_- | intronic |
| ADediting_1541188 | chr16_1815988_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_519997 | chr16_1796374_- | SINE | Alu | Name=AluSp |
| ADediting_519998 | chr16_1797567_- | SINE | Alu | Name=AluSc |
| ADediting_519999 | chr16_1797605_- | SINE | Alu | Name=AluSc |
| ADediting_520000 | chr16_1797630_- | SINE | Alu | Name=AluSc |
| ADediting_520001 | chr16_1797644_- | SINE | Alu | Name=AluSc |
| ADediting_520002 | chr16_1797715_- | SINE | Alu | Name=AluSc |
| ADediting_520003 | chr16_1798381_- | SINE | Alu | Name=AluSx |
| ADediting_520004 | chr16_1798455_- | SINE | Alu | Name=AluSx |
| ADediting_520005 | chr16_1798472_- | SINE | Alu | Name=AluSx |
| ADediting_520006 | chr16_1798475_- | SINE | Alu | Name=AluSx |
| ADediting_520007 | chr16_1798516_- | SINE | Alu | Name=AluSx |
| ADediting_520008 | chr16_1798530_- | SINE | Alu | Name=AluSx |
| ADediting_520009 | chr16_1798538_- | SINE | Alu | Name=AluSx |
| ADediting_520010 | chr16_1798543_- | SINE | Alu | Name=AluSx |
| ADediting_520011 | chr16_1798555_- | SINE | Alu | Name=AluSx |
| ADediting_520012 | chr16_1800179_- | SINE | Alu | Name=AluJb |
| ADediting_520013 | chr16_1800269_- | SINE | Alu | Name=AluJb |
| ADediting_520014 | chr16_1801192_- | SINE | Alu | Name=AluY |
| ADediting_520015 | chr16_1801224_- | SINE | Alu | Name=AluY |
| ADediting_520016 | chr16_1801225_- | SINE | Alu | Name=AluY |
| ADediting_520017 | chr16_1801281_- | SINE | Alu | Name=AluY |
| ADediting_520018 | chr16_1801285_- | SINE | Alu | Name=AluY |
| ADediting_520019 | chr16_1801289_- | SINE | Alu | Name=AluY |
| ADediting_520020 | chr16_1801295_- | SINE | Alu | Name=AluY |
| ADediting_520021 | chr16_1801324_- | SINE | Alu | Name=AluY |
| ADediting_520022 | chr16_1801331_- | SINE | Alu | Name=AluY |
| ADediting_520023 | chr16_1801340_- | SINE | Alu | Name=AluY |
| ADediting_520024 | chr16_1801351_- | SINE | Alu | Name=AluY |
| ADediting_520025 | chr16_1801588_- | SINE | Alu | Name=AluSq2 |
| ADediting_520026 | chr16_1801589_- | SINE | Alu | Name=AluSq2 |
| ADediting_520027 | chr16_1801623_- | SINE | Alu | Name=AluSq2 |
| ADediting_520028 | chr16_1802160_- | SINE | Alu | Name=AluJo |
| ADediting_520029 | chr16_1802161_- | SINE | Alu | Name=AluJo |
| ADediting_520030 | chr16_1802170_- | SINE | Alu | Name=AluJo |
| ADediting_520031 | chr16_1802176_- | SINE | Alu | Name=AluJo |
| ADediting_520032 | chr16_1802187_- | SINE | Alu | Name=AluJo |
| ADediting_520033 | chr16_1802208_- | SINE | Alu | Name=AluJo |
| ADediting_520034 | chr16_1802239_- | SINE | Alu | Name=AluJo |
| ADediting_520035 | chr16_1802256_- | SINE | Alu | Name=AluJo |
| ADediting_520036 | chr16_1802257_- | SINE | Alu | Name=AluJo |
| ADediting_520037 | chr16_1802273_- | SINE | Alu | Name=AluJo |
| ADediting_520038 | chr16_1802281_- | SINE | Alu | Name=AluJo |
| ADediting_520039 | chr16_1802283_- | SINE | Alu | Name=AluJo |
| ADediting_520040 | chr16_1802293_- | SINE | Alu | Name=AluJo |
| ADediting_520041 | chr16_1802296_- | SINE | Alu | Name=AluJo |
| ADediting_520042 | chr16_1802305_- | SINE | Alu | Name=AluJo |
| ADediting_520043 | chr16_1802306_- | SINE | Alu | Name=AluJo |
| ADediting_520044 | chr16_1802311_- | SINE | Alu | Name=AluJo |
| ADediting_520045 | chr16_1802325_- | SINE | Alu | Name=AluJo |
| ADediting_520046 | chr16_1802335_- | SINE | Alu | Name=AluJo |
| ADediting_520047 | chr16_1802340_- | SINE | Alu | Name=AluJo |
| ADediting_520048 | chr16_1802350_- | SINE | Alu | Name=AluJo |
| ADediting_520049 | chr16_1802353_- | SINE | Alu | Name=AluJo |
| ADediting_520050 | chr16_1802375_- | SINE | Alu | Name=AluJo |
| ADediting_520051 | chr16_1802917_- | SINE | Alu | Name=AluSx |
| ADediting_520052 | chr16_1802943_- | SINE | Alu | Name=AluSx |
| ADediting_520053 | chr16_1802947_- | SINE | Alu | Name=AluSx |
| ADediting_520054 | chr16_1803223_- | SINE | Alu | Name=AluSx4 |
| ADediting_520055 | chr16_1803249_- | SINE | Alu | Name=AluSx4 |
| ADediting_520056 | chr16_1803252_- | SINE | Alu | Name=AluSx4 |
| ADediting_520057 | chr16_1803253_- | SINE | Alu | Name=AluSx4 |
| ADediting_520058 | chr16_1803267_- | SINE | Alu | Name=AluSx4 |
| ADediting_520059 | chr16_1803302_- | SINE | Alu | Name=AluSx4 |
| ADediting_520060 | chr16_1803619_- | SINE | Alu | Name=AluYh3 |
| ADediting_520061 | chr16_1803623_- | SINE | Alu | Name=AluYh3 |
| ADediting_520062 | chr16_1803667_- | SINE | Alu | Name=AluYh3 |
| ADediting_520063 | chr16_1803850_- | SINE | Alu | Name=AluYh3 |
| ADediting_520064 | chr16_1804926_- | SINE | Alu | Name=AluSz |
| ADediting_520065 | chr16_1804927_- | SINE | Alu | Name=AluSz |
| ADediting_520066 | chr16_1805512_- | SINE | Alu | Name=AluJo |
| ADediting_520067 | chr16_1805517_- | SINE | Alu | Name=AluJo |
| ADediting_520068 | chr16_1806082_- | SINE | Alu | Name=AluY |
| ADediting_520069 | chr16_1806183_- | SINE | Alu | Name=AluY |
| ADediting_520070 | chr16_1806225_- | SINE | Alu | Name=AluY |
| ADediting_520071 | chr16_1806251_- | SINE | Alu | Name=AluY |
| ADediting_520072 | chr16_1806254_- | SINE | Alu | Name=AluY |
| ADediting_520073 | chr16_1806256_- | SINE | Alu | Name=AluY |
| ADediting_520074 | chr16_1806289_- | SINE | Alu | Name=AluY |
| ADediting_520075 | chr16_1806291_- | SINE | Alu | Name=AluY |
| ADediting_520076 | chr16_1806333_- | SINE | Alu | Name=AluY |
| ADediting_520077 | chr16_1806360_- | SINE | Alu | Name=AluY |
| ADediting_520078 | chr16_1806622_- | SINE | Alu | Name=AluSz6 |
| ADediting_520079 | chr16_1806655_- | SINE | Alu | Name=AluSz6 |
| ADediting_520080 | chr16_1806675_- | SINE | Alu | Name=AluSz6 |
| ADediting_520081 | chr16_1806683_- | SINE | Alu | Name=AluSz6 |
| ADediting_520082 | chr16_1806684_- | SINE | Alu | Name=AluSz6 |
| ADediting_520083 | chr16_1806695_- | SINE | Alu | Name=AluSz6 |
| ADediting_520084 | chr16_1806715_- | SINE | Alu | Name=AluSz6 |
| ADediting_520085 | chr16_1806725_- | SINE | Alu | Name=AluSz6 |
| ADediting_520086 | chr16_1806751_- | SINE | Alu | Name=AluSz6 |
| ADediting_520087 | chr16_1806769_- | SINE | Alu | Name=AluSz6 |
| ADediting_520088 | chr16_1806824_- | SINE | Alu | Name=AluSz6 |
| ADediting_520089 | chr16_1806960_- | SINE | Alu | Name=AluYf1 |
| ADediting_520090 | chr16_1807025_- | SINE | Alu | Name=AluYf1 |
| ADediting_520091 | chr16_1807102_- | SINE | Alu | Name=AluYf1 |
| ADediting_520092 | chr16_1807103_- | SINE | Alu | Name=AluYf1 |
| ADediting_520093 | chr16_1807283_- | SINE | Alu | Name=AluSx |
| ADediting_520094 | chr16_1807295_- | SINE | Alu | Name=AluSx |
| ADediting_520095 | chr16_1807296_- | SINE | Alu | Name=AluSx |
| ADediting_520096 | chr16_1807310_- | SINE | Alu | Name=AluSx |
| ADediting_520097 | chr16_1807314_- | SINE | Alu | Name=AluSx |
| ADediting_520098 | chr16_1807348_- | SINE | Alu | Name=AluSx |
| ADediting_520099 | chr16_1807374_- | SINE | Alu | Name=AluSx |
| ADediting_520100 | chr16_1807377_- | SINE | Alu | Name=AluSx |
| ADediting_520101 | chr16_1807406_- | SINE | Alu | Name=AluSx |
| ADediting_520102 | chr16_1807409_- | SINE | Alu | Name=AluSx |
| ADediting_520103 | chr16_1807417_- | SINE | Alu | Name=AluSx |
| ADediting_520104 | chr16_1807419_- | SINE | Alu | Name=AluSx |
| ADediting_520105 | chr16_1807429_- | SINE | Alu | Name=AluSx |
| ADediting_520106 | chr16_1807441_- | SINE | Alu | Name=AluSx |
| ADediting_520107 | chr16_1807458_- | SINE | Alu | Name=AluSx |
| ADediting_520108 | chr16_1807459_- | SINE | Alu | Name=AluSx |
| ADediting_520109 | chr16_1807479_- | SINE | Alu | Name=AluSx |
| ADediting_520110 | chr16_1807484_- | SINE | Alu | Name=AluSx |
| ADediting_520111 | chr16_1807494_- | SINE | Alu | Name=AluSx |
| ADediting_520112 | chr16_1807535_- | SINE | Alu | Name=AluSx |
| ADediting_520113 | chr16_1808205_- | SINE | Alu | Name=AluJb |
| ADediting_520114 | chr16_1808219_- | SINE | Alu | Name=AluJb |
| ADediting_520115 | chr16_1808223_- | SINE | Alu | Name=AluJb |
| ADediting_520116 | chr16_1808236_- | SINE | Alu | Name=AluJb |
| ADediting_520117 | chr16_1808246_- | SINE | Alu | Name=AluJb |
| ADediting_520118 | chr16_1808439_- | SINE | Alu | Name=AluYm1 |
| ADediting_520119 | chr16_1808447_- | SINE | Alu | Name=AluYm1 |
| ADediting_520120 | chr16_1808503_- | SINE | Alu | Name=AluYm1 |
| ADediting_520121 | chr16_1810070_- | SINE | Alu | Name=AluJb |
| ADediting_520122 | chr16_1810118_- | SINE | Alu | Name=AluJb |
| ADediting_520123 | chr16_1810121_- | SINE | Alu | Name=AluJb |
| ADediting_520124 | chr16_1815798_- | SINE | Alu | Name=AluSx |
| ADediting_520125 | chr16_1815856_- | SINE | Alu | Name=AluSx |
| ADediting_520126 | chr16_1815897_- | SINE | Alu | Name=AluSx |
| ADediting_520127 | chr16_1816008_- | SINE | Alu | Name=AluSc |
| ADediting_520128 | chr16_1816009_- | SINE | Alu | Name=AluSc |
| ADediting_520129 | chr16_1816033_- | SINE | Alu | Name=AluSc |
| ADediting_520130 | chr16_1816073_- | SINE | Alu | Name=AluSc |
| ADediting_520131 | chr16_1816121_- | SINE | Alu | Name=AluSx |
| ADediting_520132 | chr16_1816157_- | SINE | Alu | Name=AluSx |
| ADediting_520133 | chr16_1816168_- | SINE | Alu | Name=AluSx |
| ADediting_520135 | chr16_1823197_- | SINE | Alu | Name=AluJr |
| ADediting_520136 | chr16_1823211_- | SINE | Alu | Name=AluJr |
| ADediting_520137 | chr16_1823259_- | SINE | Alu | Name=AluY |
| ADediting_520138 | chr16_1823260_- | SINE | Alu | Name=AluY |
| ADediting_520139 | chr16_1823379_- | SINE | Alu | Name=AluY |
| ADediting_520140 | chr16_1823392_- | SINE | Alu | Name=AluY |
| ADediting_520141 | chr16_1823400_- | SINE | Alu | Name=AluY |
| ADediting_520142 | chr16_1823406_- | SINE | Alu | Name=AluY |
| ADediting_520143 | chr16_1823432_- | SINE | Alu | Name=AluY |
| ADediting_520144 | chr16_1823546_- | SINE | Alu | Name=AluY |
| ADediting_520145 | chr16_1823621_- | SINE | Alu | Name=AluJr |
| ADediting_520146 | chr16_1823643_- | SINE | Alu | Name=AluJr |
| ADediting_520147 | chr16_1824181_- | SINE | Alu | Name=AluSx3 |
| ADediting_520148 | chr16_1825074_- | SINE | Alu | Name=AluSx4 |
| ADediting_520149 | chr16_1825075_- | SINE | Alu | Name=AluSx4 |
| ADediting_520150 | chr16_1825145_- | SINE | Alu | Name=AluSx4 |
| ADediting_520151 | chr16_1825196_- | SINE | Alu | Name=AluSx4 |
| ADediting_520152 | chr16_1825206_- | SINE | Alu | Name=AluSx4 |
| ADediting_520153 | chr16_1825235_- | SINE | Alu | Name=AluSx4 |
| ADediting_520154 | chr16_1825255_- | SINE | Alu | Name=AluSx4 |
| ADediting_520155 | chr16_1825272_- | SINE | Alu | Name=AluSx4 |
| ADediting_520156 | chr16_1825616_- | SINE | Alu | Name=AluJb |
| ADediting_520157 | chr16_1825666_- | SINE | Alu | Name=AluJb |
| ADediting_520158 | chr16_1825689_- | SINE | Alu | Name=AluJb |
| ADediting_520159 | chr16_1825712_- | SINE | Alu | Name=AluJb |
| ADediting_520160 | chr16_1825792_- | SINE | Alu | Name=AluJb |
| ADediting_520161 | chr16_1825841_- | SINE | Alu | Name=AluJb |
| ADediting_520162 | chr16_1825863_- | SINE | Alu | Name=AluJb |
| ADediting_1541180 | chr16_1801190_- | SINE | Alu | Name=AluY |
| ADediting_1541181 | chr16_1801336_- | SINE | Alu | Name=AluY |
| ADediting_1541182 | chr16_1806257_- | SINE | Alu | Name=AluY |
| ADediting_1541183 | chr16_1806343_- | SINE | Alu | Name=AluY |
| ADediting_1541184 | chr16_1807275_- | SINE | Alu | Name=AluSx |
| ADediting_1541185 | chr16_1807454_- | SINE | Alu | Name=AluSx |
| ADediting_1541186 | chr16_1815853_- | SINE | Alu | Name=AluSx |
| ADediting_1541187 | chr16_1815975_- | SINE | Alu | Name=AluSc |
| ADediting_1541188 | chr16_1815988_- | SINE | Alu | Name=AluSc |
Top |
RNA A-to-I editing events in the alternative splicing sites for HAGH |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for HAGH |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for HAGH |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for HAGH |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_520113 | chr16_1808205_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-3136-3p | chr16 | 1808202 | 1808208 | 7mer-m8 | 1808201 | 1808222 | 155 | -15.46 |
| ADediting_520113 | chr16_1808205_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-7155-3p | chr16 | 1808202 | 1808208 | 7mer-m8 | 1808201 | 1808222 | 148 | -23.78 |
| ADediting_520115 | chr16_1808223_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-1913 | chr16 | 1808218 | 1808224 | 7mer-m8 | 1808217 | 1808236 | 148 | -25.01 |
| ADediting_520115 | chr16_1808223_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-6849-3p | chr16 | 1808223 | 1808229 | 7mer-m8 | 1808222 | 1808244 | 141 | -14.54 |
| ADediting_520116 | chr16_1808236_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-646 | chr16 | 1808234 | 1808240 | 7mer-m8 | 1808233 | 1808252 | 144 | -17.91 |
| ADediting_520117 | chr16_1808246_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-140-3p | chr16 | 1808244 | 1808250 | 7mer-m8 | 1808243 | 1808263 | 152 | -22.41 |
| ADediting_520118 | chr16_1808439_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-140-3p | chr16 | 1808437 | 1808443 | 7mer-m8 | 1808436 | 1808459 | 152 | -26.91 |
| ADediting_520119 | chr16_1808447_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-1271-3p | chr16 | 1808444 | 1808450 | 7mer-m8 | 1808443 | 1808465 | 163 | -28.73 |
| ADediting_520119 | chr16_1808447_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-4722-3p | chr16 | 1808447 | 1808453 | 7mer-m8 | 1808446 | 1808469 | 158 | -25.44 |
| ADediting_520119 | chr16_1808447_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-4763-5p | chr16 | 1808445 | 1808452 | 8mer-1a | 1808445 | 1808464 | 157 | -23.76 |
| ADediting_520119 | chr16_1808447_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-550a-3-5p | chr16 | 1808444 | 1808450 | 7mer-m8 | 1808443 | 1808462 | 140 | -13.29 |
| ADediting_520119 | chr16_1808447_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-550a-5p | chr16 | 1808444 | 1808450 | 7mer-m8 | 1808443 | 1808465 | 140 | -21.63 |
| ADediting_520119 | chr16_1808447_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-6727-3p | chr16 | 1808447 | 1808453 | 7mer-m8 | 1808446 | 1808465 | 157 | -24.58 |
| ADediting_520119 | chr16_1808447_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-6894-3p | chr16 | 1808445 | 1808451 | 7mer-m8 | 1808444 | 1808465 | 152 | -20.93 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_520113 | chr16_1808205_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-4437 | chr16 | 1808201 | 1808207 | 7mer-m8 | 1808200 | 1808220 | 146 | -19.53 |
| ADediting_520114 | chr16_1808219_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-1976 | chr16 | 1808215 | 1808221 | 7mer-m8 | 1808214 | 1808234 | 153 | -29.73 |
| ADediting_520114 | chr16_1808219_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-660-3p | chr16 | 1808213 | 1808220 | 8mer-1a | 1808213 | 1808232 | 144 | -16.11 |
| ADediting_520114 | chr16_1808219_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-6747-3p | chr16 | 1808216 | 1808223 | 8mer-1a | 1808216 | 1808238 | 149 | -23.42 |
| ADediting_520116 | chr16_1808236_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-6869-5p | chr16 | 1808232 | 1808238 | 7mer-m8 | 1808231 | 1808254 | 153 | -19.95 |
| ADediting_520117 | chr16_1808246_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-3169 | chr16 | 1808240 | 1808246 | 7mer-1a | 1808240 | 1808260 | 146 | -23.69 |
| ADediting_520117 | chr16_1808246_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-4759 | chr16 | 1808240 | 1808247 | 8mer-1a | 1808240 | 1808259 | 151 | -17.69 |
| ADediting_520119 | chr16_1808447_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-4288 | chr16 | 1808445 | 1808451 | 7mer-m8 | 1808444 | 1808460 | 142 | -11.62 |
| ADediting_520119 | chr16_1808447_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-4727-5p | chr16 | 1808447 | 1808453 | 7mer-m8 | 1808446 | 1808462 | 144 | -17.54 |
| ADediting_520119 | chr16_1808447_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-632 | chr16 | 1808445 | 1808451 | 7mer-m8 | 1808444 | 1808462 | 148 | -19.16 |
| ADediting_520120 | chr16_1808503_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-4716-5p | chr16 | 1808500 | 1808506 | 7mer-m8 | 1808499 | 1808520 | 140 | -11.06 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_520121 | chr16_1810070_- | ENSG00000063854.13 | ENST00000567398.1 | HAGH-210 | hsa-miR-6765-5p | chr16 | 1810065 | 1810071 | 7mer-m8 | 1810064 | 1810085 | 155 | -26.81 |
| ADediting_520122 | chr16_1810118_- | ENSG00000063854.13 | ENST00000567398.1 | HAGH-210 | hsa-miR-191-3p | chr16 | 1810115 | 1810121 | 7mer-m8 | 1810114 | 1810137 | 151 | -22.18 |
| ADediting_520123 | chr16_1810121_- | ENSG00000063854.13 | ENST00000567398.1 | HAGH-210 | hsa-miR-1227-3p | chr16 | 1810116 | 1810123 | 8mer-1a | 1810116 | 1810135 | 152 | -22.5 |
| ADediting_520123 | chr16_1810121_- | ENSG00000063854.13 | ENST00000567398.1 | HAGH-210 | hsa-miR-324-3p | chr16 | 1810120 | 1810126 | 7mer-m8 | 1810119 | 1810141 | 156 | -26.94 |
| ADediting_520123 | chr16_1810121_- | ENSG00000063854.13 | ENST00000567398.1 | HAGH-210 | hsa-miR-4252 | chr16 | 1810118 | 1810125 | 8mer-1a | 1810118 | 1810138 | 142 | -22.82 |
| ADediting_520123 | chr16_1810121_- | ENSG00000063854.13 | ENST00000567398.1 | HAGH-210 | hsa-miR-6890-3p | chr16 | 1810121 | 1810127 | 7mer-m8 | 1810120 | 1810140 | 142 | -21.85 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_520121 | chr16_1810070_- | ENSG00000063854.13 | ENST00000567398.1 | HAGH-210 | hsa-miR-1233-5p | chr16 | 1810069 | 1810075 | 7mer-m8 | 1810068 | 1810093 | 155 | -28.28 |
| ADediting_520121 | chr16_1810070_- | ENSG00000063854.13 | ENST00000567398.1 | HAGH-210 | hsa-miR-1273h-5p | chr16 | 1810070 | 1810076 | 7mer-m8 | 1810069 | 1810090 | 141 | -17.33 |
| ADediting_520121 | chr16_1810070_- | ENSG00000063854.13 | ENST00000567398.1 | HAGH-210 | hsa-miR-30b-3p | chr16 | 1810070 | 1810076 | 7mer-m8 | 1810069 | 1810092 | 142 | -16.35 |
| ADediting_520121 | chr16_1810070_- | ENSG00000063854.13 | ENST00000567398.1 | HAGH-210 | hsa-miR-3689a-3p | chr16 | 1810070 | 1810076 | 7mer-m8 | 1810069 | 1810090 | 142 | -16.46 |
| ADediting_520121 | chr16_1810070_- | ENSG00000063854.13 | ENST00000567398.1 | HAGH-210 | hsa-miR-3689b-3p | chr16 | 1810070 | 1810076 | 7mer-m8 | 1810069 | 1810090 | 142 | -17.95 |
| ADediting_520121 | chr16_1810070_- | ENSG00000063854.13 | ENST00000567398.1 | HAGH-210 | hsa-miR-3689c | chr16 | 1810070 | 1810076 | 7mer-m8 | 1810069 | 1810090 | 142 | -17.95 |
| ADediting_520121 | chr16_1810070_- | ENSG00000063854.13 | ENST00000567398.1 | HAGH-210 | hsa-miR-6778-5p | chr16 | 1810069 | 1810075 | 7mer-m8 | 1810068 | 1810093 | 154 | -30.37 |
| ADediting_520121 | chr16_1810070_- | ENSG00000063854.13 | ENST00000567398.1 | HAGH-210 | hsa-miR-6779-5p | chr16 | 1810070 | 1810076 | 7mer-m8 | 1810069 | 1810086 | 147 | -19.96 |
| ADediting_520121 | chr16_1810070_- | ENSG00000063854.13 | ENST00000567398.1 | HAGH-210 | hsa-miR-6780a-5p | chr16 | 1810070 | 1810076 | 7mer-m8 | 1810069 | 1810091 | 141 | -21.68 |
| ADediting_520122 | chr16_1810118_- | ENSG00000063854.13 | ENST00000567398.1 | HAGH-210 | hsa-miR-5008-3p | chr16 | 1810115 | 1810121 | 7mer-m8 | 1810114 | 1810132 | 148 | -18.67 |
| ADediting_520122 | chr16_1810118_- | ENSG00000063854.13 | ENST00000567398.1 | HAGH-210 | hsa-miR-5089-3p | chr16 | 1810118 | 1810124 | 7mer-m8 | 1810117 | 1810139 | 140 | -15.92 |
| ADediting_520123 | chr16_1810121_- | ENSG00000063854.13 | ENST00000567398.1 | HAGH-210 | hsa-miR-5089-3p | chr16 | 1810118 | 1810124 | 7mer-m8 | 1810117 | 1810139 | 140 | -15.92 |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-589-3p | chr16 | 1808014 | 1808020 | 7mer-m8 | 1808013 | 1808037 | 145 | -18.47 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-641 | chr16 | 1808686 | 1808692 | 7mer-m8 | 1808685 | 1808709 | 141 | -20.19 |
| ADediting_496066 | chr15_66496985_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-4512 | chr16 | 1808878 | 1808884 | 7mer-m8 | 1808877 | 1808898 | 154 | -18.21 |
| ADediting_496066 | chr15_66496985_- | ENSG00000063854.13 | ENST00000455446.6 | HAGH-203 | hsa-miR-4512 | chr16 | 1808878 | 1808884 | 7mer-m8 | 1808877 | 1808898 | 154 | -18.21 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-5585-3p | chr16 | 1808082 | 1808088 | 7mer-m8 | 1808081 | 1808104 | 156 | -18.15 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-5688 | chr16 | 1807687 | 1807693 | 7mer-m8 | 1807686 | 1807707 | 144 | -8.62 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000063854.13 | ENST00000566644.5 | HAGH-207 | hsa-miR-5688 | chr16 | 1807687 | 1807693 | 7mer-m8 | 1807686 | 1807707 | 144 | -8.62 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-589-3p | chr16 | 1808051 | 1808058 | 8mer-1a | 1808051 | 1808078 | 143 | -22.37 |
| ADediting_291761 | chr11_93733708_- | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-1304-3p | chr16 | 1808006 | 1808012 | 7mer-m8 | 1808005 | 1808027 | 142 | -14.65 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-5585-3p | chr16 | 1808034 | 1808040 | 7mer-m8 | 1808033 | 1808056 | 147 | -9.49 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000063854.13 | ENST00000397356.8 | HAGH-202 | hsa-miR-5585-3p | chr16 | 1808034 | 1808040 | 7mer-m8 | 1808033 | 1808056 | 147 | -9.49 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for HAGH |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000397356.8 | protein_coding |  |  |
| ENST00000567398.1 | lncRNA |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_520113 | ENST00000397356.8 | chr16_1808205_- | 2043 | -1092.90 | -1090.90 | -1112.50 |
| ADediting_520114 | ENST00000397356.8 | chr16_1808219_- | 2029 | -1091.70 | -1090.90 | -1112.50 |
| ADediting_520115 | ENST00000397356.8 | chr16_1808223_- | 2025 | -1091.00 | -1090.90 | -1112.50 |
| ADediting_520116 | ENST00000397356.8 | chr16_1808236_- | 2012 | -1095.40 | -1090.90 | -1112.50 |
| ADediting_520117 | ENST00000397356.8 | chr16_1808246_- | 2002 | -1094.30 | -1090.90 | -1112.50 |
| ADediting_520118 | ENST00000397356.8 | chr16_1808439_- | 1809 | -1091.10 | -1090.90 | -1112.50 |
| ADediting_520119 | ENST00000397356.8 | chr16_1808447_- | 1801 | -1090.80 | -1090.90 | -1112.50 |
| ADediting_520120 | ENST00000397356.8 | chr16_1808503_- | 1745 | -1091.90 | -1090.90 | -1112.50 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_520121 | ENST00000567398.1 | chr16_1810070_- | 879 | -571.60 | -567.60 | -571.20 |
| ADediting_520122 | ENST00000567398.1 | chr16_1810118_- | 831 | -567.20 | -567.60 | -571.20 |
| ADediting_520123 | ENST00000567398.1 | chr16_1810121_- | 828 | -567.60 | -567.60 | -571.20 |
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Relation with ADAR for HAGH |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_520003 | chr16_1798381_- | 0.26805941192157 | 0.0910039766439173 | 2.77511341239474e-05 | 0.335065761851329 | 0.0847790567723982 | 0.141207029622694 |
| DLPFC | ADediting_520005 | chr16_1798472_- | 0.512836960702601 | -0.0373067054433294 | 0.0170762068163636 | -0.135385139237715 | 6.13553882787097e-12 | 0.377534221776603 |
| DLPFC | ADediting_520006 | chr16_1798475_- | 0.701448163269032 | -0.0218594493417085 | 0.0527432829458588 | -0.110125212134575 | 9.36734450210345e-10 | 0.338628661576267 |
| CER | ADediting_520017 | chr16_1801281_- | 0.0331239988256663 | 0.174086597430104 | 0.000130900525552579 | 0.307271199509702 | 0.00377016342096674 | 0.235161978843485 |
| CER | ADediting_520020 | chr16_1801295_- | 0.00639334898128419 | 0.221726463511615 | 1.79833336367437e-06 | 0.37843244767879 | 0.00355382756640167 | 0.236620318296548 |
| CER | ADediting_520026 | chr16_1801589_- | 0.00116792002690228 | 0.262612234941976 | 7.60814682359777e-05 | 0.317306254905212 | 0.418481954274181 | 0.0665426853956853 |
| CER | ADediting_520030 | chr16_1802170_- | 3.3608731590873e-05 | 0.331776784154476 | 4.86171146245702e-05 | 0.325328391510138 | 0.00941104053679876 | 0.211390526271195 |
| DLPFC | ADediting_520032 | chr16_1802187_- | 5.21842835605391e-05 | 0.227670967794477 | 7.63364291090287e-10 | 0.340320446527228 | 0.0381955886923399 | 0.117789993599082 |
| CER | ADediting_520034 | chr16_1802239_- | 0.000985103375808354 | 0.266366106932645 | 6.72895668297199e-06 | 0.358310827273027 | 0.0351813041226279 | 0.172130035393755 |
| CER | ADediting_520039 | chr16_1802283_- | 0.00757026832733303 | 0.217264729882067 | 7.58189723155109e-05 | 0.31736904077972 | 0.217876443012096 | 0.101196322034464 |
| DLPFC | ADediting_520040 | chr16_1802293_- | 9.64293196095502e-06 | 0.248378752929804 | 6.05843229038388e-11 | 0.360467206371049 | 0.0358710368708026 | 0.119236526498463 |
| CER | ADediting_520040 | chr16_1802293_- | 0.000301667515367744 | 0.291089770130794 | 5.15591510872218e-06 | 0.362481866723423 | 0.808942867052943 | 0.0199066448994176 |
| CER | ADediting_520049 | chr16_1802353_- | 0.00223856481012653 | 0.247741021317169 | 1.51870753451056e-05 | 0.345182064992345 | 0.0470241029374214 | 0.162443179324698 |
| CER | ADediting_520050 | chr16_1802375_- | 0.053243077015819 | 0.158152512361957 | 2.28603615160534e-05 | 0.338357707018284 | 0.0420966008284906 | 0.16619247035345 |
| CER | ADediting_520051 | chr16_1802917_- | 6.0465613986233e-06 | 0.359992869172635 | 3.65920527411174e-09 | 0.458406699888743 | 0.0750057047073214 | 0.145813267012292 |
| CER | ADediting_520054 | chr16_1803223_- | 0.000437422783384846 | 0.283569307647362 | 1.10157366076906e-06 | 0.385575747343706 | 0.0088616353042796 | 0.213028697187372 |
| CER | ADediting_520061 | chr16_1803623_- | 0.000264705192952233 | 0.293686649015757 | 2.95016937975152e-05 | 0.334019272917975 | 0.720755088533419 | 0.029425491390722 |
| CER | ADediting_520064 | chr16_1804926_- | 1.92187995732794e-05 | 0.341272704234284 | 3.80387244269392e-07 | 0.400517880400876 | 0.0120158501791575 | 0.204614845169631 |
| CER | ADediting_520071 | chr16_1806251_- | 0.00233169999011948 | 0.246779815422328 | 7.98730593590716e-08 | 0.421207468864361 | 0.00133802925373319 | 0.259574471060546 |
| CER | ADediting_520076 | chr16_1806333_- | 0.0294745344823656 | 0.177826255146272 | 2.77252124832536e-05 | 0.335081719806978 | 0.00130465587052807 | 0.260141465115872 |
| CER | ADediting_520079 | chr16_1806655_- | 0.00611665731443581 | 0.22288105130776 | 0.000103492759632019 | 0.311659907116327 | 0.0188369701171126 | 0.191596559893029 |
| CER | ADediting_520080 | chr16_1806675_- | 0.00814108422417148 | 0.215319064737916 | 4.0394828591583e-07 | 0.399692619799503 | 0.471622869131497 | 0.059218557808316 |
| CER | ADediting_520085 | chr16_1806725_- | 9.19812768618151e-06 | 0.353338374480641 | 3.24756900241904e-09 | 0.459760626503142 | 0.108419690879199 | 0.131605379792859 |
| CER | ADediting_520086 | chr16_1806751_- | 0.000129470164454702 | 0.307477984532623 | 2.89888945343885e-10 | 0.48597507216807 | 0.173143406445437 | 0.11180719187993 |
| CER | ADediting_520089 | chr16_1806960_- | 0.00382852168973712 | 0.234781488506428 | 8.11387750603749e-05 | 0.316134587374984 | 0.165722682651793 | 0.113756804771041 |
| CER | ADediting_520093 | chr16_1807283_- | 0.00512977656566285 | 0.227418785976852 | 0.000160643307018639 | 0.30338944289757 | 0.470053275026507 | 0.0594280749707657 |
| CER | ADediting_520096 | chr16_1807310_- | 0.000127588660132626 | 0.307753259964142 | 0.00022039084395777 | 0.297285809229685 | 0.225949161393454 | 0.0994529417060983 |
| CER | ADediting_520097 | chr16_1807314_- | 0.000507086525212955 | 0.280519211593368 | 4.56431643829933e-06 | 0.364371633926525 | 0.0630986500892028 | 0.152133689276458 |
| CER | ADediting_520099 | chr16_1807374_- | 0.0388393313488479 | 0.168878044645859 | 0.00188687446457967 | 0.251732030908782 | 0.000131094044821109 | 0.307243384754856 |
| CER | ADediting_520100 | chr16_1807377_- | 0.00231786435031294 | 0.246920380592912 | 2.15625503932649e-06 | 0.375743466444071 | 0.00972238473099974 | 0.210499324222349 |
| CER | ADediting_520111 | chr16_1807494_- | 0.0275356688436619 | 0.179976299731089 | 9.35900962227475e-06 | 0.353060076816476 | 0.0487573747247954 | 0.161202135913032 |
| CER | ADediting_520114 | chr16_1808219_- | 0.0439342440500233 | 0.164753356030269 | 8.15358017982861e-07 | 0.389878702588728 | 0.000765253382772519 | 0.271837838639345 |
| CER | ADediting_520128 | chr16_1816009_- | 0.0366923892630204 | 0.170753643932174 | 0.000165747148564012 | 0.302791683007399 | 0.742800348796219 | 0.0270142040326531 |
| DLPFC | ADediting_520129 | chr16_1816033_- | 0.421709238156895 | 0.0457944818531653 | 0.304878385778249 | -0.0584607883466137 | 2.58497159374004e-17 | 0.455868976522589 |
| CER | ADediting_520132 | chr16_1816157_- | 0.352035354564959 | 0.0765157611406268 | 0.000115406151282634 | 0.309633093900654 | 0.00973972977927289 | 0.21045041942251 |
| DLPFC | ADediting_520133 | chr16_1816168_- | 0.141214968397668 | 0.0837546439922325 | 0.908343879526869 | -0.00656526739184328 | 2.79795906666399e-08 | 0.308924434491952 |
| CER | ADediting_520133 | chr16_1816168_- | 0.212150628985848 | 0.102460911778782 | 6.88760484829663e-05 | 0.319108205065425 | 0.0216271376086361 | 0.187439953403991 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 2.61199030483288e-52 | 0.727432906787869 | 4.75150341121313e-71 | 0.802491361351578 | 1.28791939060626e-11 | 0.372116733458932 |
| AC | 4.00618947635845e-83 | 0.882284008530064 | 5.77798704339961e-65 | 0.830493325097477 | 4.63363508791619e-12 | 0.41921504408071 |
| PCC | 4.08795229041618e-44 | 0.801728975440386 | 9.89698486981961e-51 | 0.834163762743443 | 0.0534720222717608 | 0.139958920678654 |
| CER | 1.91260548766283e-14 | 0.57264248547242 | 2.4035415455225e-09 | 0.463149143120001 | 0.235150047255543 | -0.097518764879605 |
| TCX | 2.20133178627518e-21 | 0.676206704547593 | 3.93173052749412e-24 | 0.708120356098898 | 0.175245977989188 | -0.11126607450077 |
| FP | 7.69416922816787e-19 | 0.60074330513086 | 5.39809125286043e-15 | 0.542239374459347 | 0.148634925803888 | 0.108704883329068 |
| IFG | 1.21229133362501e-05 | 0.756496652357065 | 4.52411306998535e-06 | 0.778810946918164 | 0.895753795582407 | -0.0276142659829763 |
| PG | 0.00262828505236391 | 0.21935554076911 | 8.83294636408374e-06 | 0.319421051135822 | 0.670973909827124 | -0.0313524053315618 |
| STG | 1.26543159295381e-19 | 0.79675599048289 | 8.08400286159447e-12 | 0.660594136645821 | 0.500368144767851 | 0.0745442343222451 |
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Relation with AD stages for HAGH |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_520020 | chr16_1801295_- | 3.28096329515079e-05 | 0.388343173844265 |
| CER | ADediting_520049 | chr16_1802353_- | 0.000968105877700863 | 0.313127019840585 |
| CER | ADediting_520081 | chr16_1806683_- | 0.0015447401371799 | 0.301064519581723 |
| CER | ADediting_520086 | chr16_1806751_- | 0.00156595622237032 | 0.300704657120328 |
| CER | ADediting_520097 | chr16_1807314_- | 0.000951668852518254 | 0.313559652214638 |
| CER | ADediting_520114 | chr16_1808219_- | 0.000536647397314534 | 0.327675160192982 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| PG | 7.30413227822386e-07 | -0.353751103443205 |
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RelatedDrugs for HAGH |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| HAGH | Q16775 | DB00143 | Glutathione | Hydroxyacylglutathione hydrolase, mitochondrial {ECO:0000303|PubMed:15117945} | small molecule | approved|investigational|nutraceutical |
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RelatedDiseases for HAGH |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| HAGH | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| HAGH | C0036341 | Schizophrenia | 1 | PSYGENET |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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