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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for ERO1A

check button Gene summary
Gene informationGene symbol

ERO1A

Gene ID

30001

Gene nameendoplasmic reticulum oxidoreductase 1 alpha
SynonymsERO1-L|ERO1-L-alpha|ERO1-alpha|ERO1L|ERO1LA|Ero1alpha
Cytomap

14q22.1

Type of geneprotein-coding
DescriptionERO1-like protein alphaendoplasmic oxidoreductin-1-like proteinendoplasmic reticulum oxidoreductase alphaoxidoreductin-1-L-alpha
Modification date20200313
UniProtAcc

Q96HE7,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
ERO1A

GO:0051085

chaperone cofactor-dependent protein refolding

11707400


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RNA A-to-I events for ERO1A

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_435161(52642959, -), ADediting_435162(52642960, -), ADediting_435163(52643014, -), ADediting_435164(52643092, -), ADediting_435165(52643105, -), ADediting_435166(52644251, -), ADediting_435167(52645388, -), ADediting_435168(52645399, -), ADediting_435169(52645408, -), ADediting_435170(52645414, -), ADediting_435171(52645459, -), ADediting_435172(52645482, -), ADediting_435173(52645506, -), ADediting_435174(52645507, -), ADediting_435175(52645538, -), ADediting_435176(52645543, -), ADediting_435177(52645560, -), ADediting_435178(52645579, -), ADediting_435179(52645748, -), ADediting_435180(52645912, -), ADediting_435181(52645927, -), ADediting_435182(52645928, -), ADediting_435183(52645967, -), ADediting_435184(52645979, -), ADediting_435185(52646034, -), ADediting_435186(52647072, -), ADediting_435187(52647087, -), ADediting_435188(52647114, -), ADediting_435189(52647272, -), ADediting_435190(52647273, -), ADediting_435191(52649971, -), ADediting_435192(52650124, -), ADediting_435193(52651024, -), ADediting_435194(52651025, -), ADediting_435195(52651051, -), ADediting_435196(52651052, -), ADediting_435197(52651065, -), ADediting_435198(52651066, -), ADediting_435199(52652050, -), ADediting_435200(52652051, -), ADediting_435201(52652104, -), ADediting_435202(52652105, -), ADediting_435203(52664830, -), ADediting_435204(52664836, -), ADediting_435205(52664846, -), ADediting_435206(52665202, -), ADediting_435207(52665226, -), ADediting_435208(52666868, -), ADediting_435209(52669963, -), ADediting_435210(52670053, -), ADediting_435211(52670075, -), ADediting_435212(52670079, -), ADediting_435213(52670110, -), ADediting_435214(52670172, -), ADediting_435215(52670175, -), ADediting_435216(52670518, -), ADediting_435217(52672547, -), ADediting_435218(52672581, -), ADediting_435219(52673197, -), ADediting_435220(52673234, -), ADediting_435221(52673241, -), ADediting_435222(52673340, -), ADediting_435223(52673362, -), ADediting_435224(52675166, -), ADediting_435225(52675167, -), ADediting_435226(52675181, -), ADediting_435227(52675191, -), ADediting_435228(52675192, -), ADediting_435229(52675713, -), ADediting_435230(52675758, -), ADediting_435231(52675759, -), ADediting_435232(52675773, -), ADediting_435233(52675799, -), ADediting_435234(52675971, -), ADediting_435235(52678142, -), ADediting_435236(52678144, -), ADediting_435237(52688030, -), ADediting_435238(52688991, -), ADediting_435239(52689032, -), ADediting_435240(52689093, -), ADediting_435241(52690497, -), ADediting_435242(52690524, -), ADediting_435243(52690549, -), ADediting_435244(52690687, -), ADediting_435245(52690695, -), ADediting_435246(52690999, -), ADediting_435247(52691048, -), ADediting_435248(52693200, -), ADediting_435249(52693770, -), ADediting_1536982(52659936, -), ADediting_1536983(52660037, -), ADediting_1619318(52643107, -), ADediting_1619319(52644209, -), ADediting_1619320(52665190, -), ADediting_1619321(52667627, -), ADediting_1619322(52667689, -), ADediting_1619323(52670088, -), ADediting_1619324(52679574, -), ADediting_1619325(52679640, -), ADediting_1619326(52679644, -), ADediting_1619327(52679648, -), ADediting_1619328(52679825, -),

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RNA editing positional annotations for ERO1A using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_435161chr14_52642959_-UTR3
ADediting_435162chr14_52642960_-UTR3
ADediting_435163chr14_52643014_-UTR3
ADediting_435164chr14_52643092_-UTR3
ADediting_435165chr14_52643105_-UTR3
ADediting_435166chr14_52644251_-intronic
ADediting_435167chr14_52645388_-intronic
ADediting_435168chr14_52645399_-intronic
ADediting_435169chr14_52645408_-intronic
ADediting_435170chr14_52645414_-intronic
ADediting_435171chr14_52645459_-intronic
ADediting_435172chr14_52645482_-intronic
ADediting_435173chr14_52645506_-intronic
ADediting_435174chr14_52645507_-intronic
ADediting_435175chr14_52645538_-intronic
ADediting_435176chr14_52645543_-intronic
ADediting_435177chr14_52645560_-intronic
ADediting_435178chr14_52645579_-intronic
ADediting_435179chr14_52645748_-intronic
ADediting_435180chr14_52645912_-intronic
ADediting_435181chr14_52645927_-intronic
ADediting_435182chr14_52645928_-intronic
ADediting_435183chr14_52645967_-intronic
ADediting_435184chr14_52645979_-intronic
ADediting_435185chr14_52646034_-intronic
ADediting_435186chr14_52647072_-intronic
ADediting_435187chr14_52647087_-intronic
ADediting_435188chr14_52647114_-intronic
ADediting_435189chr14_52647272_-intronic
ADediting_435190chr14_52647273_-intronic
ADediting_435191chr14_52649971_-intronic
ADediting_435192chr14_52650124_-intronic
ADediting_435193chr14_52651024_-intronic
ADediting_435194chr14_52651025_-intronic
ADediting_435195chr14_52651051_-intronic
ADediting_435196chr14_52651052_-intronic
ADediting_435197chr14_52651065_-intronic
ADediting_435198chr14_52651066_-intronic
ADediting_435199chr14_52652050_-intronic
ADediting_435200chr14_52652051_-intronic
ADediting_435201chr14_52652104_-intronic
ADediting_435202chr14_52652105_-intronic
ADediting_435203chr14_52664830_-intronic
ADediting_435204chr14_52664836_-intronic
ADediting_435205chr14_52664846_-intronic
ADediting_435206chr14_52665202_-intronic
ADediting_435207chr14_52665226_-intronic
ADediting_435208chr14_52666868_-intronic
ADediting_435209chr14_52669963_-intronic
ADediting_435210chr14_52670053_-intronic
ADediting_435211chr14_52670075_-intronic
ADediting_435212chr14_52670079_-intronic
ADediting_435213chr14_52670110_-intronic
ADediting_435214chr14_52670172_-intronic
ADediting_435215chr14_52670175_-intronic
ADediting_435216chr14_52670518_-intronic
ADediting_435217chr14_52672547_-intronic
ADediting_435218chr14_52672581_-intronic
ADediting_435219chr14_52673197_-intronic
ADediting_435220chr14_52673234_-intronic
ADediting_435221chr14_52673241_-intronic
ADediting_435222chr14_52673340_-intronic
ADediting_435223chr14_52673362_-intronic
ADediting_435224chr14_52675166_-intronic
ADediting_435225chr14_52675167_-intronic
ADediting_435226chr14_52675181_-intronic
ADediting_435227chr14_52675191_-intronic
ADediting_435228chr14_52675192_-intronic
ADediting_435229chr14_52675713_-intronic
ADediting_435230chr14_52675758_-intronic
ADediting_435231chr14_52675759_-intronic
ADediting_435232chr14_52675773_-intronic
ADediting_435233chr14_52675799_-intronic
ADediting_435234chr14_52675971_-intronic
ADediting_435235chr14_52678142_-intronic
ADediting_435236chr14_52678144_-intronic
ADediting_435237chr14_52688030_-intronic
ADediting_435238chr14_52688991_-intronic
ADediting_435239chr14_52689032_-intronic
ADediting_435240chr14_52689093_-intronic
ADediting_435241chr14_52690497_-intronic
ADediting_435242chr14_52690524_-intronic
ADediting_435243chr14_52690549_-intronic
ADediting_435244chr14_52690687_-intronic
ADediting_435245chr14_52690695_-intronic
ADediting_435246chr14_52690999_-intronic
ADediting_435247chr14_52691048_-intronic
ADediting_435248chr14_52693200_-intronic
ADediting_435249chr14_52693770_-intronic
ADediting_1536982chr14_52659936_-intronic
ADediting_1536983chr14_52660037_-intronic
ADediting_1619318chr14_52643107_-UTR3
ADediting_1619319chr14_52644209_-intronic
ADediting_1619320chr14_52665190_-intronic
ADediting_1619321chr14_52667627_-intronic
ADediting_1619322chr14_52667689_-intronic
ADediting_1619323chr14_52670088_-intronic
ADediting_1619324chr14_52679574_-intronic
ADediting_1619325chr14_52679640_-intronic
ADediting_1619326chr14_52679644_-intronic
ADediting_1619327chr14_52679648_-intronic
ADediting_1619328chr14_52679825_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_435162chr14_52642960_-DNAhAT-BlackjackName=MER53
ADediting_435163chr14_52643014_-DNAhAT-BlackjackName=MER53
ADediting_435164chr14_52643092_-DNAhAT-BlackjackName=MER53
ADediting_435165chr14_52643105_-DNAhAT-BlackjackName=MER53
ADediting_435166chr14_52644251_-SINEAluName=AluSz6
ADediting_435167chr14_52645388_-SINEAluName=AluSz
ADediting_435168chr14_52645399_-SINEAluName=AluSz
ADediting_435169chr14_52645408_-SINEAluName=AluSz
ADediting_435170chr14_52645414_-SINEAluName=AluSz
ADediting_435171chr14_52645459_-SINEAluName=AluSz
ADediting_435172chr14_52645482_-SINEAluName=AluSz
ADediting_435173chr14_52645506_-SINEAluName=AluSz
ADediting_435174chr14_52645507_-SINEAluName=AluSz
ADediting_435175chr14_52645538_-SINEAluName=AluSz
ADediting_435176chr14_52645543_-SINEAluName=AluSz
ADediting_435177chr14_52645560_-SINEAluName=AluSz
ADediting_435178chr14_52645579_-SINEAluName=AluSz
ADediting_435179chr14_52645748_-SINEAluName=AluSx
ADediting_435180chr14_52645912_-SINEAluName=AluSx
ADediting_435181chr14_52645927_-SINEAluName=AluSx
ADediting_435182chr14_52645928_-SINEAluName=AluSx
ADediting_435183chr14_52645967_-SINEAluName=AluSx
ADediting_435184chr14_52645979_-SINEAluName=AluSx
ADediting_435185chr14_52646034_-SINEAluName=AluSx
ADediting_435186chr14_52647072_-SINEAluName=AluY
ADediting_435187chr14_52647087_-SINEAluName=AluY
ADediting_435188chr14_52647114_-SINEAluName=AluY
ADediting_435189chr14_52647272_-SINEAluName=AluY
ADediting_435190chr14_52647273_-SINEAluName=AluY
ADediting_435191chr14_52649971_-SINEAluName=AluJr
ADediting_435192chr14_52650124_-SINEAluName=AluJr
ADediting_435193chr14_52651024_-SINEAluName=AluJo
ADediting_435194chr14_52651025_-SINEAluName=AluJo
ADediting_435195chr14_52651051_-SINEAluName=AluJo
ADediting_435196chr14_52651052_-SINEAluName=AluJo
ADediting_435197chr14_52651065_-SINEAluName=AluJo
ADediting_435198chr14_52651066_-SINEAluName=AluJo
ADediting_435199chr14_52652050_-SINEAluName=FLAM_C
ADediting_435200chr14_52652051_-SINEAluName=FLAM_C
ADediting_435201chr14_52652104_-SINEAluName=FLAM_C
ADediting_435202chr14_52652105_-SINEAluName=FLAM_C
ADediting_435203chr14_52664830_-SINEAluName=AluY
ADediting_435204chr14_52664836_-SINEAluName=AluY
ADediting_435205chr14_52664846_-SINEAluName=AluY
ADediting_435206chr14_52665202_-SINEAluName=AluSx
ADediting_435207chr14_52665226_-SINEAluName=AluSx
ADediting_435208chr14_52666868_-SINEAluName=AluSz
ADediting_435209chr14_52669963_-SINEAluName=AluJr
ADediting_435210chr14_52670053_-SINEAluName=AluJr
ADediting_435211chr14_52670075_-SINEAluName=AluJr
ADediting_435212chr14_52670079_-SINEAluName=AluJr
ADediting_435213chr14_52670110_-SINEAluName=AluJr
ADediting_435214chr14_52670172_-SINEAluName=AluJr
ADediting_435215chr14_52670175_-SINEAluName=AluJr
ADediting_435216chr14_52670518_-SINEAluName=AluSc
ADediting_435217chr14_52672547_-SINEAluName=AluJr4
ADediting_435218chr14_52672581_-SINEAluName=AluJr4
ADediting_435219chr14_52673197_-SINEAluName=AluJb
ADediting_435220chr14_52673234_-SINEAluName=AluJb
ADediting_435221chr14_52673241_-SINEAluName=AluJb
ADediting_435222chr14_52673340_-SINEAluName=AluJb
ADediting_435223chr14_52673362_-SINEAluName=AluJb
ADediting_435224chr14_52675166_-SINEAluName=AluSq2
ADediting_435225chr14_52675167_-SINEAluName=AluSq2
ADediting_435226chr14_52675181_-SINEAluName=AluSq2
ADediting_435227chr14_52675191_-SINEAluName=AluSq2
ADediting_435228chr14_52675192_-SINEAluName=AluSq2
ADediting_435229chr14_52675713_-SINEAluName=AluJb
ADediting_435230chr14_52675758_-SINEAluName=AluJb
ADediting_435231chr14_52675759_-SINEAluName=AluJb
ADediting_435232chr14_52675773_-SINEAluName=AluJb
ADediting_435233chr14_52675799_-SINEAluName=AluJb
ADediting_435234chr14_52675971_-SINEAluName=AluJb
ADediting_435235chr14_52678142_-SINEAluName=AluSp
ADediting_435236chr14_52678144_-SINEAluName=AluSp
ADediting_435237chr14_52688030_-SINEAluName=AluJr
ADediting_435238chr14_52688991_-SINEAluName=AluSq2
ADediting_435239chr14_52689032_-SINEAluName=AluSq2
ADediting_435240chr14_52689093_-SINEAluName=AluSq2
ADediting_435241chr14_52690497_-SINEAluName=AluSx1
ADediting_435242chr14_52690524_-SINEAluName=AluSx1
ADediting_435243chr14_52690549_-SINEAluName=AluSx1
ADediting_435244chr14_52690687_-SINEAluName=AluSx1
ADediting_435245chr14_52690695_-SINEAluName=AluSx1
ADediting_435246chr14_52690999_-SINEAluName=AluSp
ADediting_435247chr14_52691048_-SINEAluName=AluSp
ADediting_435248chr14_52693200_-SINEAluName=AluJb
ADediting_435249chr14_52693770_-SINEAluName=AluJb
ADediting_1536982chr14_52659936_-SINEAluName=AluSz
ADediting_1536983chr14_52660037_-SINEAluName=AluSz
ADediting_1619318chr14_52643107_-DNAhAT-BlackjackName=MER53
ADediting_1619319chr14_52644209_-SINEAluName=AluSz6
ADediting_1619320chr14_52665190_-SINEAluName=AluSx
ADediting_1619321chr14_52667627_-SINEAluName=AluJb
ADediting_1619322chr14_52667689_-SINEAluName=AluJb
ADediting_1619323chr14_52670088_-SINEAluName=AluJr
ADediting_1619324chr14_52679574_-SINEAluName=AluSx1
ADediting_1619325chr14_52679640_-SINEAluName=AluSx1
ADediting_1619326chr14_52679644_-SINEAluName=AluSx1
ADediting_1619327chr14_52679648_-SINEAluName=AluSx1
ADediting_1619328chr14_52679825_-SINEAluName=AluJb

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RNA A-to-I editing events in the alternative splicing sites for ERO1A

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ERO1A

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot
boxplot
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for ERO1A

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for ERO1A

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1619318chr14_52643107_-ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-153-5pchr1452643106526431138mer-1a5264310652643126153-12.53
ADediting_435161chr14_52642959_-ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-630chr1452642953526429608mer-1a5264295352642978151-16.11
ADediting_435162chr14_52642960_-ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-205-3pchr1452642955526429628mer-1a5264295552642980144-11.65
ADediting_435165chr14_52643105_-ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-500a-5pchr1452643101526431077mer-m85264310052643122143-11.54

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_435161chr14_52642959_-ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-651-5pchr1452642958526429658mer-1a5264295852642978146-11.6
ADediting_435162chr14_52642960_-ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-651-5pchr1452642958526429658mer-1a5264295852642978146-11.6
ADediting_435163chr14_52643014_-ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-5692achr1452643011526430177mer-m85264301052643031141-9.8

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1471003chr9_63819626_+ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-4477bchr1452640906526409127mer-m85264090552640926145-13.33
ADediting_1471003chr9_63819626_+ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-4477bchr1452642622526426287mer-m85264262152642644163-19.06
ADediting_1471004chr9_63819627_+ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-4477bchr1452640546526405527mer-m85264054552640571142-15.04
ADediting_1471004chr9_63819627_+ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-4477bchr1452641943526419497mer-m85264194252641963153-15.76
ADediting_1471004chr9_63819627_+ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-4477bchr1452642203526422108mer-1a5264220352642224145-10.55
ADediting_286380chr11_79422188_-ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-5579-3pchr1452643475526434828mer-1a5264347552643495152-17.04

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-589-3pchr1452640450526404567mer-m85264044952640472144-15.65
ADediting_1471003chr9_63819626_+ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-4477bchr1452640147526401537mer-m85264014652640165143-7.99
ADediting_1471003chr9_63819626_+ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-4477bchr1452641022526410298mer-1a5264102252641042151-10.44
ADediting_1471003chr9_63819626_+ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-4477bchr1452641244526412507mer-m85264124352641266143-9.12
ADediting_1471004chr9_63819627_+ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-4477bchr1452640147526401537mer-m85264014652640165143-7.99
ADediting_1471004chr9_63819627_+ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-4477bchr1452641022526410298mer-1a5264102252641042151-10.44
ADediting_1471004chr9_63819627_+ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-4477bchr1452641244526412507mer-m85264124352641266143-9.12
ADediting_1535953chr14_101045971_+ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-381-3pchr1452642977526429837mer-m85264297652642997141-16.08
ADediting_1535954chr14_101045974_+ENSG00000197930.13ENST00000395686.8ERO1A-201hsa-miR-381-3pchr1452642977526429837mer-m85264297652642997141-16.08

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ERO1A

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000395686.8protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_435161ENST00000395686.8chr14_52642959_-2095-1278.70-1278.60-1283.30
ADediting_435162ENST00000395686.8chr14_52642960_-2094-1278.70-1278.60-1283.30
ADediting_435163ENST00000395686.8chr14_52643014_-2040-1284.20-1278.60-1283.30
ADediting_435164ENST00000395686.8chr14_52643092_-1962-1278.20-1278.60-1283.30
ADediting_435165ENST00000395686.8chr14_52643105_-1949-1278.30-1278.60-1283.30
ADediting_1619318ENST00000395686.8chr14_52643107_-1947-1278.70-1278.60-1283.30

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for ERO1A

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_435167chr14_52645388_-0.08937077761661210.09664562160385630.744486893614177-0.01858433860741932.44489342966278e-140.415044173127835
DLPFCADediting_435170chr14_52645414_-0.01032940769479680.1454716691233720.85501972910206-0.01041946378170281.77606157525117e-230.526209373722593

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC6.82861123755402e-660.7845436822442713.46651958935323e-450.6902334654583731.37045814843404e-070.293823878100815
AC4.28618640826641e-1120.9330361724487161.87801436873824e-860.8897715847006185.25173039221256e-060.283537802204754
PCC1.47476557646057e-730.908535805194297.44461821846922e-760.9137442915899660.0305686047485340.1565449279078
CER2.7408072955754e-460.8655191846090327.86253923233001e-260.7259151088714070.04657257108778260.162772724789094
TCX8.72632990894531e-410.8380907047737064.23477191296686e-180.6319752224331630.7311808875925620.028282137750563
FP1.31190602439173e-180.5975310950615812.05697767262306e-280.7082338943023820.7209254087792370.0269600142531018
IFG0.0001794022985800460.6809021723721120.005349653030643320.5398146017978920.9313421230387730.0181596126159226
PG8.83106247378238e-500.835737340667076.33696741717448e-420.7956951988713440.0826101334066085-0.127609913913385
STG7.70867243535258e-160.7410135719244691.22072479574736e-190.7969555726852210.837531256802602-0.0227104481928594

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Relation with AD stages for ERO1A

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER0.001557155257267130.300853396711854

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RelatedDrugs for ERO1A

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ERO1A

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource