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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for ZDHHC8 |
 Gene summary |
| Gene information | Gene symbol | ZDHHC8 | Gene ID | 29801 |
| Gene name | zinc finger DHHC-type palmitoyltransferase 8 | |
| Synonyms | DHHC8|ZDHHCL1|ZNF378 | |
| Cytomap | 22q11.21 | |
| Type of gene | protein-coding | |
| Description | probable palmitoyltransferase ZDHHC8membrane-associated DHHC8 zinc finger proteinzinc finger DHHC-type containing 8zinc finger protein 378zinc finger, DHHC domain like containing 1 | |
| Modification date | 20200313 | |
| UniProtAcc | Q9ULC8, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| ZDHHC8 | GO:0018345 | protein palmitoylation | 23034182 |
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RNA A-to-I events for ZDHHC8 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_969537(20133473, +), ADediting_969538(20133474, +), ADediting_969539(20133495, +), ADediting_969540(20133496, +), ADediting_969541(20133543, +), ADediting_969542(20133552, +), ADediting_969543(20133582, +), ADediting_969544(20133586, +), ADediting_969545(20133609, +), ADediting_969546(20133614, +), ADediting_969547(20133618, +), ADediting_969548(20133620, +), ADediting_969549(20133622, +), ADediting_969550(20133625, +), ADediting_969551(20133627, +), ADediting_969552(20133632, +), ADediting_969553(20133635, +), ADediting_969554(20133639, +), ADediting_969555(20133673, +), ADediting_969556(20133674, +), ADediting_969557(20133692, +), ADediting_969558(20134955, +), ADediting_969559(20134963, +), ADediting_969560(20134971, +), ADediting_969561(20134975, +), ADediting_969562(20134980, +), ADediting_969563(20134982, +), ADediting_969564(20135032, +), ADediting_969565(20135044, +), ADediting_969566(20135049, +), ADediting_969567(20135058, +), ADediting_969568(20135061, +), ADediting_969569(20135071, +), ADediting_969570(20135073, +), ADediting_969571(20135089, +), ADediting_969572(20135131, +), ADediting_969573(20135134, +), ADediting_969574(20135179, +), ADediting_969575(20135197, +), ADediting_969576(20135206, +), ADediting_969577(20135219, +), ADediting_969578(20135324, +), ADediting_1569748(20133542, +), ADediting_1569749(20135174, +), |
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RNA editing positional annotations for ZDHHC8 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_969537 | chr22_20133473_+ | intronic |
| ADediting_969538 | chr22_20133474_+ | intronic |
| ADediting_969539 | chr22_20133495_+ | intronic |
| ADediting_969540 | chr22_20133496_+ | intronic |
| ADediting_969541 | chr22_20133543_+ | intronic |
| ADediting_969542 | chr22_20133552_+ | intronic |
| ADediting_969543 | chr22_20133582_+ | intronic |
| ADediting_969544 | chr22_20133586_+ | intronic |
| ADediting_969545 | chr22_20133609_+ | intronic |
| ADediting_969546 | chr22_20133614_+ | intronic |
| ADediting_969547 | chr22_20133618_+ | intronic |
| ADediting_969548 | chr22_20133620_+ | intronic |
| ADediting_969549 | chr22_20133622_+ | intronic |
| ADediting_969550 | chr22_20133625_+ | intronic |
| ADediting_969551 | chr22_20133627_+ | intronic |
| ADediting_969552 | chr22_20133632_+ | intronic |
| ADediting_969553 | chr22_20133635_+ | intronic |
| ADediting_969554 | chr22_20133639_+ | intronic |
| ADediting_969555 | chr22_20133673_+ | intronic |
| ADediting_969556 | chr22_20133674_+ | intronic |
| ADediting_969557 | chr22_20133692_+ | intronic |
| ADediting_969558 | chr22_20134955_+ | intronic |
| ADediting_969559 | chr22_20134963_+ | intronic |
| ADediting_969560 | chr22_20134971_+ | intronic |
| ADediting_969561 | chr22_20134975_+ | intronic |
| ADediting_969562 | chr22_20134980_+ | intronic |
| ADediting_969563 | chr22_20134982_+ | intronic |
| ADediting_969564 | chr22_20135032_+ | intronic |
| ADediting_969565 | chr22_20135044_+ | intronic |
| ADediting_969566 | chr22_20135049_+ | intronic |
| ADediting_969567 | chr22_20135058_+ | intronic |
| ADediting_969568 | chr22_20135061_+ | intronic |
| ADediting_969569 | chr22_20135071_+ | intronic |
| ADediting_969570 | chr22_20135073_+ | intronic |
| ADediting_969571 | chr22_20135089_+ | intronic |
| ADediting_969572 | chr22_20135131_+ | intronic |
| ADediting_969573 | chr22_20135134_+ | intronic |
| ADediting_969574 | chr22_20135179_+ | intronic |
| ADediting_969575 | chr22_20135197_+ | intronic |
| ADediting_969576 | chr22_20135206_+ | intronic |
| ADediting_969577 | chr22_20135219_+ | intronic |
| ADediting_969578 | chr22_20135324_+ | intronic |
| ADediting_1569748 | chr22_20133542_+ | intronic |
| ADediting_1569749 | chr22_20135174_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_969537 | chr22_20133473_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969538 | chr22_20133474_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969539 | chr22_20133495_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969540 | chr22_20133496_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969541 | chr22_20133543_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969542 | chr22_20133552_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969543 | chr22_20133582_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969544 | chr22_20133586_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969545 | chr22_20133609_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969546 | chr22_20133614_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969547 | chr22_20133618_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969548 | chr22_20133620_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969549 | chr22_20133622_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969550 | chr22_20133625_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969551 | chr22_20133627_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969552 | chr22_20133632_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969553 | chr22_20133635_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969554 | chr22_20133639_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969555 | chr22_20133673_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969556 | chr22_20133674_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969557 | chr22_20133692_+ | SINE | Alu | Name=AluSx1 |
| ADediting_969558 | chr22_20134955_+ | SINE | Alu | Name=AluJb |
| ADediting_969559 | chr22_20134963_+ | SINE | Alu | Name=AluJb |
| ADediting_969560 | chr22_20134971_+ | SINE | Alu | Name=AluJb |
| ADediting_969561 | chr22_20134975_+ | SINE | Alu | Name=AluJb |
| ADediting_969562 | chr22_20134980_+ | SINE | Alu | Name=AluJb |
| ADediting_969563 | chr22_20134982_+ | SINE | Alu | Name=AluJb |
| ADediting_969564 | chr22_20135032_+ | SINE | Alu | Name=AluJb |
| ADediting_969565 | chr22_20135044_+ | SINE | Alu | Name=AluJb |
| ADediting_969566 | chr22_20135049_+ | SINE | Alu | Name=AluJb |
| ADediting_969567 | chr22_20135058_+ | SINE | Alu | Name=AluJb |
| ADediting_969568 | chr22_20135061_+ | SINE | Alu | Name=AluJb |
| ADediting_969569 | chr22_20135071_+ | SINE | Alu | Name=AluJb |
| ADediting_969570 | chr22_20135073_+ | SINE | Alu | Name=AluJb |
| ADediting_969571 | chr22_20135089_+ | SINE | Alu | Name=AluJb |
| ADediting_969572 | chr22_20135131_+ | SINE | Alu | Name=AluJb |
| ADediting_969573 | chr22_20135134_+ | SINE | Alu | Name=AluJb |
| ADediting_969574 | chr22_20135179_+ | SINE | Alu | Name=AluJb |
| ADediting_969575 | chr22_20135197_+ | SINE | Alu | Name=AluJb |
| ADediting_969576 | chr22_20135206_+ | SINE | Alu | Name=AluJb |
| ADediting_969577 | chr22_20135219_+ | SINE | Alu | Name=AluJb |
| ADediting_1569748 | chr22_20133542_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1569749 | chr22_20135174_+ | SINE | Alu | Name=AluJb |
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RNA A-to-I editing events in the alternative splicing sites for ZDHHC8 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZDHHC8 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for ZDHHC8 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for ZDHHC8 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000099904.15 | ENST00000320602.11 | ZDHHC8-201 | hsa-miR-589-3p | chr22 | 20145952 | 20145958 | 7mer-m8 | 20145938 | 20145959 | 145 | -23.62 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000099904.15 | ENST00000334554.11 | ZDHHC8-202 | hsa-miR-589-3p | chr22 | 20145952 | 20145958 | 7mer-m8 | 20145938 | 20145959 | 145 | -23.62 |
| ADediting_286380 | chr11_79422188_- | ENSG00000099904.15 | ENST00000334554.11 | ZDHHC8-202 | hsa-miR-5579-3p | chr22 | 20147523 | 20147529 | 7mer-m8 | 20147509 | 20147530 | 140 | -9.67 |
| ADediting_286380 | chr11_79422188_- | ENSG00000099904.15 | ENST00000405930.3 | ZDHHC8-203 | hsa-miR-5579-3p | chr22 | 20147523 | 20147529 | 7mer-m8 | 20147509 | 20147530 | 140 | -9.67 |
| ADediting_527135 | chr16_24203190_+ | ENSG00000099904.15 | ENST00000320602.11 | ZDHHC8-201 | hsa-miR-1273h-3p | chr22 | 20146265 | 20146271 | 7mer-m8 | 20146251 | 20146272 | 150 | -20.33 |
| ADediting_527135 | chr16_24203190_+ | ENSG00000099904.15 | ENST00000334554.11 | ZDHHC8-202 | hsa-miR-1273h-3p | chr22 | 20146265 | 20146271 | 7mer-m8 | 20146251 | 20146272 | 150 | -20.33 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_291761 | chr11_93733708_- | ENSG00000099904.15 | ENST00000320602.11 | ZDHHC8-201 | hsa-miR-1304-3p | chr22 | 20145663 | 20145669 | 7mer-m8 | 20145645 | 20145670 | 149 | -20.44 |
| ADediting_291761 | chr11_93733708_- | ENSG00000099904.15 | ENST00000334554.11 | ZDHHC8-202 | hsa-miR-1304-3p | chr22 | 20145663 | 20145669 | 7mer-m8 | 20145645 | 20145670 | 149 | -20.44 |
| ADediting_496066 | chr15_66496985_- | ENSG00000099904.15 | ENST00000320602.11 | ZDHHC8-201 | hsa-miR-4512 | chr22 | 20146219 | 20146225 | 7mer-m8 | 20146205 | 20146226 | 142 | -14.25 |
| ADediting_496066 | chr15_66496985_- | ENSG00000099904.15 | ENST00000334554.11 | ZDHHC8-202 | hsa-miR-4512 | chr22 | 20146219 | 20146225 | 7mer-m8 | 20146205 | 20146226 | 142 | -14.25 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for ZDHHC8 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for ZDHHC8 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_969537 | chr22_20133473_+ | 0.000584165759616725 | 0.277565872034979 | 7.4575035139497e-10 | 0.475985122716825 | 0.000165392978189067 | 0.302832605981698 |
| CER | ADediting_969539 | chr22_20133495_+ | 0.0110327738601695 | 0.207004414973045 | 2.27908932329342e-05 | 0.338409088050361 | 0.0200528143821436 | 0.18972401808039 |
| CER | ADediting_969541 | chr22_20133543_+ | 0.00919468104179697 | 0.212025300251786 | 1.373061628366e-06 | 0.382385795302413 | 0.000663737514343981 | 0.27487227326028 |
| CER | ADediting_969542 | chr22_20133552_+ | 0.00878766695681516 | 0.213256064963867 | 6.13572973604394e-06 | 0.359763152159359 | 0.000652381578396628 | 0.275237870149068 |
| CER | ADediting_969545 | chr22_20133609_+ | 0.297544025107423 | 0.0856155688838099 | 0.000787859315747832 | 0.271212821341914 | 1.3408746375653e-05 | 0.347228980051202 |
| CER | ADediting_969546 | chr22_20133614_+ | 0.0344101067146278 | 0.172851838756898 | 8.31944019404003e-06 | 0.35494472778775 | 0.000300761863562573 | 0.291149783507411 |
| CER | ADediting_969549 | chr22_20133622_+ | 0.221987419777486 | 0.10030289948412 | 0.00011987674487576 | 0.308922637629086 | 0.0173592449862397 | 0.194018811842336 |
| CER | ADediting_969550 | chr22_20133625_+ | 0.0564484271655502 | 0.156101092248123 | 1.03992543994161e-05 | 0.351362830553333 | 0.000629990087791282 | 0.27597624475172 |
| CER | ADediting_969553 | chr22_20133635_+ | 0.0477119117338323 | 0.16194621765533 | 2.10175575277588e-06 | 0.376124168487162 | 0.00744841549313469 | 0.217696870547747 |
| CER | ADediting_969557 | chr22_20133692_+ | 0.000969473997095451 | 0.266716019962411 | 1.53118024157251e-07 | 0.412749442746801 | 0.00325535899715152 | 0.238769461677557 |
| CER | ADediting_969559 | chr22_20134963_+ | 0.00878116847619786 | 0.213276121120681 | 1.17026300496864e-05 | 0.34944962200647 | 0.0334310694393314 | 0.173788146346406 |
| CER | ADediting_969561 | chr22_20134975_+ | 0.000962765385398287 | 0.266867801884605 | 2.59348189026573e-05 | 0.336219390410923 | 0.010787586317247 | 0.207629489399453 |
| CER | ADediting_969562 | chr22_20134980_+ | 0.00544235220207378 | 0.225902869200888 | 2.19279941140236e-05 | 0.339059917267765 | 0.00289373436598084 | 0.241625451515862 |
| CER | ADediting_969564 | chr22_20135032_+ | 8.89100604349984e-05 | 0.314461000060532 | 3.26179005808274e-05 | 0.332293184478285 | 0.000538270631692707 | 0.279277589403478 |
| CER | ADediting_969565 | chr22_20135044_+ | 0.000188530487599464 | 0.300316504516499 | 6.21352868069613e-10 | 0.477939746800339 | 0.0507046857146112 | 0.159850828873653 |
| CER | ADediting_969567 | chr22_20135058_+ | 0.00231128066579453 | 0.246987535749262 | 7.52802650352174e-05 | 0.317498532838452 | 0.814913631106071 | 0.0192729758673407 |
| CER | ADediting_969569 | chr22_20135071_+ | 0.000435333362029595 | 0.283667555480949 | 1.37608192350717e-06 | 0.382353809259259 | 0.00456627460346292 | 0.23037368002139 |
| CER | ADediting_969572 | chr22_20135131_+ | 4.67977029552652e-06 | 0.363985273692745 | 2.20366114029295e-08 | 0.437290477979873 | 0.0199462745486753 | 0.189884118446879 |
| CER | ADediting_969573 | chr22_20135134_+ | 0.000314830465960783 | 0.290235870435675 | 1.75646833962932e-07 | 0.410935315823527 | 0.210789762592025 | 0.102765047539886 |
| CER | ADediting_969574 | chr22_20135179_+ | 0.00793916558389047 | 0.21599308255241 | 2.57589985063722e-05 | 0.33633506858218 | 0.0842186534448009 | 0.14145929217994 |
| CER | ADediting_969575 | chr22_20135197_+ | 8.15831816797011e-05 | 0.316034919709246 | 7.46477738335135e-07 | 0.391129516891723 | 0.00156559880176921 | 0.256020401988988 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 3.83418471013197e-23 | 0.522784786807257 | 2.22085898451064e-28 | 0.572406762332366 | 2.26228776491747e-25 | 0.544922028569556 |
| AC | 2.36755738706823e-30 | 0.641219140240584 | 4.67410925634394e-30 | 0.638703030597706 | 1.93632214922676e-19 | 0.529132636574589 |
| PCC | 7.42882101630698e-21 | 0.61004697890098 | 8.43428114837161e-25 | 0.655191737635247 | 1.29805765504392e-07 | 0.370718320400808 |
| CER | 7.18594604146462e-10 | 0.476383419839007 | 9.18020084605243e-23 | 0.692748050034372 | 1.61125270720862e-06 | 0.380048194494815 |
| TCX | 5.17209279834181e-16 | 0.599615390638687 | 2.32232292093459e-07 | 0.407211133014101 | 7.61498473255969e-11 | 0.49958016457172 |
| FP | 1.82292774060108e-10 | 0.454681001513159 | 0.00852916815756079 | 0.196611681168093 | 8.05300089299457e-14 | 0.521834506099372 |
| IFG | 1.42909157128142e-05 | 0.75252763736898 | 7.10400085441708e-06 | 0.768896903566164 | 0.0232566450273109 | 0.452143995778496 |
| STG | 1.22260606854465e-06 | 0.500839031681548 | 0.0721093872551554 | 0.197247335428813 | 0.000367413928024507 | 0.379719012685697 |
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Relation with AD stages for ZDHHC8 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_969542 | chr22_20133552_+ | 0.000261342101419455 | 0.344497573870203 |
| CER | ADediting_969562 | chr22_20134980_+ | 0.000157490646235632 | 0.355796041605415 |
| CER | ADediting_969564 | chr22_20135032_+ | 0.000233645599192745 | 0.347033477422752 |
| CER | ADediting_969565 | chr22_20135044_+ | 0.000327268604759937 | 0.339339574161345 |
| CER | ADediting_969569 | chr22_20135071_+ | 5.41944501220846e-05 | 0.378301305733804 |
| CER | ADediting_969574 | chr22_20135179_+ | 6.75503800856117e-06 | 0.41799693780496 |
| CER | ADediting_969575 | chr22_20135197_+ | 1.66466666980402e-07 | 0.478140305985131 |
| CER | ADediting_969577 | chr22_20135219_+ | 0.000464411103132945 | 0.331132678727023 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 2.3688212803791e-09 | 0.535414011914015 |
| TCX | 2.95969726760906e-08 | 0.506839122274143 |
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RelatedDrugs for ZDHHC8 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ZDHHC8 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| ZDHHC8 | C0036341 | Schizophrenia | 5 | PSYGENET |
| ZDHHC8 | C0005586 | Bipolar Disorder | 1 | PSYGENET |
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