|
||||||
|
 | |
| |
| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
| |
| |
| The effects of the RNA editing to the stability of the RNA structures |
| |
| |
| |
|
Gene summary for TRIM59 |
 Gene summary |
| Gene information | Gene symbol | TRIM59 | Gene ID | 286827 |
| Gene name | tripartite motif containing 59 | |
| Synonyms | IFT80L|MRF1|RNF104|TRIM57|TSBF1 | |
| Cytomap | 3q25.33 | |
| Type of gene | protein-coding | |
| Description | tripartite motif-containing protein 59RING finger protein 104tripartite motif-containing 57tumor suppressor TSBF-1tumor suppressor TSBF1 | |
| Modification date | 20200327 | |
| UniProtAcc | Q8IWR1, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for TRIM59 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_1035443(160435202, -), ADediting_1035444(160435234, -), ADediting_1035445(160435283, -), ADediting_1035446(160435350, -), ADediting_1035447(160435376, -), ADediting_1035448(160435378, -), ADediting_1035449(160436573, -), ADediting_1035450(160436609, -), ADediting_1035451(160436631, -), ADediting_1035452(160436634, -), ADediting_1035453(160437167, -), ADediting_1035454(160437232, -), ADediting_1035455(160479807, -), ADediting_1035456(160479854, -), ADediting_1035457(160480687, -), ADediting_1035458(160480757, -), ADediting_1035459(160480767, -), ADediting_1035460(160480799, -), ADediting_1035461(160480802, -), ADediting_1035462(160481578, -), ADediting_1035463(160481588, -), ADediting_1035464(160481666, -), ADediting_1572780(160436540, -), ADediting_1572781(160437228, -), ADediting_1572782(160437242, -), ADediting_1572783(160480915, -), |
Top |
RNA editing positional annotations for TRIM59 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1035443 | chr3_160435202_- | UTR3 |
| ADediting_1035444 | chr3_160435234_- | UTR3 |
| ADediting_1035445 | chr3_160435283_- | UTR3 |
| ADediting_1035446 | chr3_160435350_- | UTR3 |
| ADediting_1035447 | chr3_160435376_- | UTR3 |
| ADediting_1035448 | chr3_160435378_- | UTR3 |
| ADediting_1035449 | chr3_160436573_- | UTR3 |
| ADediting_1035450 | chr3_160436609_- | UTR3 |
| ADediting_1035451 | chr3_160436631_- | UTR3 |
| ADediting_1035452 | chr3_160436634_- | UTR3 |
| ADediting_1035453 | chr3_160437167_- | UTR3 |
| ADediting_1035454 | chr3_160437232_- | UTR3 |
| ADediting_1035455 | chr3_160479807_- | intronic |
| ADediting_1035456 | chr3_160479854_- | intronic |
| ADediting_1035457 | chr3_160480687_- | intronic |
| ADediting_1035458 | chr3_160480757_- | intronic |
| ADediting_1035459 | chr3_160480767_- | intronic |
| ADediting_1035460 | chr3_160480799_- | intronic |
| ADediting_1035461 | chr3_160480802_- | intronic |
| ADediting_1035462 | chr3_160481578_- | intronic |
| ADediting_1035463 | chr3_160481588_- | intronic |
| ADediting_1035464 | chr3_160481666_- | intronic |
| ADediting_1572780 | chr3_160436540_- | UTR3 |
| ADediting_1572781 | chr3_160437228_- | UTR3 |
| ADediting_1572782 | chr3_160437242_- | UTR3 |
| ADediting_1572783 | chr3_160480915_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1035443 | chr3_160435202_- | SINE | Alu | Name=AluSz6 |
| ADediting_1035444 | chr3_160435234_- | SINE | Alu | Name=AluSz6 |
| ADediting_1035445 | chr3_160435283_- | SINE | Alu | Name=AluSz6 |
| ADediting_1035446 | chr3_160435350_- | SINE | Alu | Name=AluSz6 |
| ADediting_1035447 | chr3_160435376_- | SINE | Alu | Name=AluSz6 |
| ADediting_1035448 | chr3_160435378_- | SINE | Alu | Name=AluSz6 |
| ADediting_1035449 | chr3_160436573_- | SINE | Alu | Name=AluY |
| ADediting_1035450 | chr3_160436609_- | SINE | Alu | Name=AluY |
| ADediting_1035451 | chr3_160436631_- | SINE | Alu | Name=AluY |
| ADediting_1035452 | chr3_160436634_- | SINE | Alu | Name=AluY |
| ADediting_1035453 | chr3_160437167_- | SINE | Alu | Name=AluJb |
| ADediting_1035454 | chr3_160437232_- | SINE | Alu | Name=AluJb |
| ADediting_1035455 | chr3_160479807_- | SINE | Alu | Name=AluSp |
| ADediting_1035456 | chr3_160479854_- | SINE | Alu | Name=AluSp |
| ADediting_1035457 | chr3_160480687_- | SINE | Alu | Name=AluSx1 |
| ADediting_1035458 | chr3_160480757_- | SINE | Alu | Name=AluSx1 |
| ADediting_1035459 | chr3_160480767_- | SINE | Alu | Name=AluSx1 |
| ADediting_1035460 | chr3_160480799_- | SINE | Alu | Name=AluSx1 |
| ADediting_1035461 | chr3_160480802_- | SINE | Alu | Name=AluSx1 |
| ADediting_1035462 | chr3_160481578_- | SINE | Alu | Name=AluSx1 |
| ADediting_1035463 | chr3_160481588_- | SINE | Alu | Name=AluSx1 |
| ADediting_1035464 | chr3_160481666_- | SINE | Alu | Name=AluSx1 |
| ADediting_1572780 | chr3_160436540_- | SINE | Alu | Name=AluY |
| ADediting_1572781 | chr3_160437228_- | SINE | Alu | Name=AluJb |
| ADediting_1572782 | chr3_160437242_- | SINE | Alu | Name=AluJb |
| ADediting_1572783 | chr3_160480915_- | SINE | Alu | Name=AluSx1 |
Top |
RNA A-to-I editing events in the alternative splicing sites for TRIM59 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for TRIM59 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
 | |
 | |
| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
 |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
 |
 |
 |
| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for TRIM59 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for TRIM59 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1035443 | chr3_160435202_- | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-4437 | chr3 | 160435199 | 160435205 | 7mer-m8 | 160435198 | 160435220 | 151 | -22.3 |
| ADediting_1035444 | chr3_160435234_- | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-1207-3p | chr3 | 160435234 | 160435240 | 7mer-m8 | 160435233 | 160435251 | 145 | -13.53 |
| ADediting_1035444 | chr3_160435234_- | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-646 | chr3 | 160435232 | 160435238 | 7mer-m8 | 160435231 | 160435250 | 148 | -20.6 |
| ADediting_1035445 | chr3_160435283_- | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-4677-5p | chr3 | 160435279 | 160435285 | 7mer-m8 | 160435278 | 160435298 | 146 | -13.8 |
| ADediting_1035446 | chr3_160435350_- | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-4707-3p | chr3 | 160435346 | 160435353 | 8mer-1a | 160435346 | 160435367 | 162 | -27.57 |
| ADediting_1035447 | chr3_160435376_- | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-3619-3p | chr3 | 160435371 | 160435378 | 8mer-1a | 160435371 | 160435396 | 146 | -20.47 |
| ADediting_1035447 | chr3_160435376_- | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-4776-5p | chr3 | 160435371 | 160435377 | 7mer-m8 | 160435370 | 160435389 | 153 | -25.03 |
| ADediting_1035448 | chr3_160435378_- | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-7151-3p | chr3 | 160435376 | 160435382 | 7mer-m8 | 160435375 | 160435391 | 146 | -22.21 |
| ADediting_1035450 | chr3_160436609_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-3190-5p | chr3 | 160436604 | 160436610 | 7mer-m8 | 160436603 | 160436621 | 148 | -20.6 |
| ADediting_1035450 | chr3_160436609_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-548s | chr3 | 160436605 | 160436611 | 7mer-m8 | 160436604 | 160436626 | 149 | -15.9 |
| ADediting_1035453 | chr3_160437167_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-196a-3p | chr3 | 160437162 | 160437168 | 7mer-m8 | 160437161 | 160437182 | 151 | -14.23 |
| ADediting_1035453 | chr3_160437167_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-942-3p | chr3 | 160437166 | 160437172 | 7mer-m8 | 160437165 | 160437185 | 152 | -15.18 |
| ADediting_1035454 | chr3_160437232_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-339-5p | chr3 | 160437230 | 160437236 | 7mer-m8 | 160437229 | 160437249 | 161 | -26.63 |
| ADediting_1035454 | chr3_160437232_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-6748-3p | chr3 | 160437231 | 160437237 | 7mer-m8 | 160437230 | 160437249 | 157 | -25.34 |
| ADediting_1035454 | chr3_160437232_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-874-3p | chr3 | 160437228 | 160437234 | 7mer-m8 | 160437227 | 160437248 | 153 | -25.08 |
| ADediting_1572782 | chr3_160437242_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-6743-3p | chr3 | 160437240 | 160437246 | 7mer-m8 | 160437239 | 160437261 | 141 | -16.39 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1035443 | chr3_160435202_- | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-498-5p | chr3 | 160435202 | 160435208 | 7mer-m8 | 160435201 | 160435224 | 144 | -12.4 |
| ADediting_1035444 | chr3_160435234_- | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-6869-5p | chr3 | 160435230 | 160435236 | 7mer-m8 | 160435229 | 160435252 | 152 | -21.27 |
| ADediting_1035446 | chr3_160435350_- | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-6747-3p | chr3 | 160435348 | 160435354 | 7mer-m8 | 160435347 | 160435368 | 150 | -22.22 |
| ADediting_1035447 | chr3_160435376_- | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-625-3p | chr3 | 160435374 | 160435380 | 7mer-m8 | 160435373 | 160435394 | 144 | -12.62 |
| ADediting_1035448 | chr3_160435378_- | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-625-3p | chr3 | 160435374 | 160435380 | 7mer-m8 | 160435373 | 160435394 | 144 | -12.62 |
| ADediting_1035449 | chr3_160436573_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-3681-5p | chr3 | 160436571 | 160436577 | 7mer-m8 | 160436570 | 160436591 | 155 | -14.91 |
| ADediting_1035449 | chr3_160436573_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-6849-5p | chr3 | 160436571 | 160436577 | 7mer-m8 | 160436570 | 160436592 | 148 | -22.94 |
| ADediting_1035450 | chr3_160436609_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-664a-5p | chr3 | 160436604 | 160436610 | 7mer-m8 | 160436603 | 160436625 | 148 | -14.11 |
| ADediting_1035451 | chr3_160436631_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-3675-3p | chr3 | 160436626 | 160436632 | 7mer-m8 | 160436625 | 160436646 | 145 | -12.88 |
| ADediting_1035451 | chr3_160436631_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-4684-5p | chr3 | 160436627 | 160436633 | 7mer-m8 | 160436626 | 160436648 | 152 | -14.44 |
| ADediting_1035453 | chr3_160437167_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-5583-3p | chr3 | 160437165 | 160437171 | 7mer-m8 | 160437164 | 160437186 | 155 | -9.75 |
| ADediting_1035454 | chr3_160437232_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-4312 | chr3 | 160437228 | 160437235 | 8mer-1a | 160437228 | 160437246 | 154 | -19.73 |
| ADediting_1035454 | chr3_160437232_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-4646-3p | chr3 | 160437232 | 160437238 | 7mer-m8 | 160437231 | 160437251 | 145 | -18.12 |
| ADediting_1572781 | chr3_160437228_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-550b-2-5p | chr3 | 160437226 | 160437232 | 7mer-m8 | 160437225 | 160437246 | 140 | -12.81 |
| ADediting_1572781 | chr3_160437228_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-6867-5p | chr3 | 160437223 | 160437229 | 7mer-m8 | 160437222 | 160437244 | 141 | -12.99 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-589-3p | chr3 | 160436779 | 160436785 | 7mer-m8 | 160436778 | 160436802 | 162 | -21.11 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-4477b | chr3 | 160434580 | 160434586 | 7mer-m8 | 160434579 | 160434601 | 158 | -16.2 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-4775 | chr3 | 160437522 | 160437529 | 8mer-1a | 160437522 | 160437546 | 151 | -11.64 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-4775 | chr3 | 160433005 | 160433011 | 7mer-m8 | 160433004 | 160433030 | 153 | -13.19 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-4775 | chr3 | 160433169 | 160433176 | 8mer-1a | 160433169 | 160433190 | 143 | -10.31 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-4775 | chr3 | 160433851 | 160433857 | 7mer-m8 | 160433850 | 160433872 | 155 | -8.53 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-5585-3p | chr3 | 160437419 | 160437425 | 7mer-m8 | 160437418 | 160437438 | 144 | -11.39 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_107020 | chr1_37500952_- | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-5581-3p | chr3 | 160437902 | 160437908 | 7mer-m8 | 160437901 | 160437922 | 145 | -16.29 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-5688 | chr3 | 160433658 | 160433664 | 7mer-m8 | 160433657 | 160433678 | 145 | -12.92 |
| ADediting_1596844 | chr1_162342605_+ | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-556-3p | chr3 | 160434236 | 160434243 | 8mer-1a | 160434236 | 160434257 | 141 | -7.22 |
| ADediting_291761 | chr11_93733708_- | ENSG00000213186.8 | ENST00000543469.1 | TRIM59-208 | hsa-miR-1304-3p | chr3 | 160435134 | 160435141 | 8mer-1a | 160435134 | 160435155 | 153 | -21.61 |
| ADediting_527135 | chr16_24203190_+ | ENSG00000213186.8 | ENST00000309784.9 | TRIM59-201 | hsa-miR-1273h-3p | chr3 | 160436925 | 160436932 | 8mer-1a | 160436925 | 160436945 | 154 | -17.31 |
| Differentially expressed gene-miRNA network |
Top |
The effects of the RNA editing to the stability of the RNA structures for TRIM59 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000543469.1 | protein_coding |  |  |
| ENST00000309784.9 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1035443 | ENST00000543469.1 | chr3_160435202_- | 1858 | -1071.50 | -1065.90 | -1074.70 |
| ADediting_1035444 | ENST00000543469.1 | chr3_160435234_- | 1826 | -1065.60 | -1065.90 | -1074.70 |
| ADediting_1035445 | ENST00000543469.1 | chr3_160435283_- | 1777 | -1068.20 | -1065.90 | -1074.70 |
| ADediting_1035446 | ENST00000543469.1 | chr3_160435350_- | 1710 | -1065.80 | -1065.90 | -1074.70 |
| ADediting_1035447 | ENST00000543469.1 | chr3_160435376_- | 1684 | -1069.40 | -1065.90 | -1074.70 |
| ADediting_1035448 | ENST00000543469.1 | chr3_160435378_- | 1682 | -1071.10 | -1065.90 | -1074.70 |
| ADediting_1572780 | ENST00000309784.9 | chr3_160436540_- | 2787 | -955.20 | -951.40 | -965.20 |
| ADediting_1035449 | ENST00000309784.9 | chr3_160436573_- | 2754 | -952.70 | -951.40 | -965.20 |
| ADediting_1035450 | ENST00000309784.9 | chr3_160436609_- | 2718 | -954.50 | -951.40 | -965.20 |
| ADediting_1035451 | ENST00000309784.9 | chr3_160436631_- | 2696 | -952.90 | -951.40 | -965.20 |
| ADediting_1035452 | ENST00000309784.9 | chr3_160436634_- | 2693 | -952.50 | -951.40 | -965.20 |
| ADediting_1035453 | ENST00000309784.9 | chr3_160437167_- | 2160 | -951.80 | -951.40 | -965.20 |
| ADediting_1572781 | ENST00000309784.9 | chr3_160437228_- | 2099 | -950.90 | -951.40 | -965.20 |
| ADediting_1035454 | ENST00000309784.9 | chr3_160437232_- | 2095 | -953.40 | -951.40 | -965.20 |
| ADediting_1572782 | ENST00000309784.9 | chr3_160437242_- | 2085 | -954.40 | -951.40 | -965.20 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
Top |
Relation with ADAR for TRIM59 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 5.60142305102271e-12 | 0.378192751613 | 1.39491571778471e-07 | 0.293650795138363 | 3.6774909900755e-33 | 0.611368520748962 |
| AC | 1.4575078469131e-20 | 0.542866053461187 | 1.24538144750711e-12 | 0.429277671427279 | 8.62453236010866e-37 | 0.690803074441514 |
| PCC | 9.76426544238434e-05 | 0.278172989993199 | 0.00025022593443246 | 0.262049636066443 | 3.11961386394425e-11 | 0.456718455995315 |
| CER | 0.00587933826722252 | 0.223909054055636 | 0.0623380824132634 | 0.152569546560076 | 4.1273549568096e-06 | 0.365923020162205 |
| TCX | 0.0109269276888224 | 0.207272741960319 | 0.00650094889998167 | -0.221289458564188 | 1.19936658236061e-19 | 0.653743623801573 |
| FP | 5.77660664756557e-05 | 0.29671679650151 | 2.77244836356307e-08 | 0.401552342571499 | 1.70283389961162e-11 | 0.476887284340816 |
| IFG | 0.955639882509384 | 0.0117251054123021 | 0.412577985943388 | -0.171431332675877 | 0.0108731869334977 | 0.500267617686774 |
| PG | 1.42318457794062e-17 | 0.572292077417344 | 5.94882478920805e-07 | 0.356403844630683 | 6.92239028263912e-06 | 0.3229664821768 |
| STG | 4.84678515066382e-05 | 0.42816703674056 | 0.0142600338151057 | 0.26652520998481 | 8.49938325912513e-08 | 0.54468124243377 |
Top |
Relation with AD stages for TRIM59 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 9.51508163476432e-05 | 0.36663360553782 |
| TCX | 0.000914243351741387 | 0.317438193907798 |
Top |
RelatedDrugs for TRIM59 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for TRIM59 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| TRIM59 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|