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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for RNF180

check button Gene summary
Gene informationGene symbol

RNF180

Gene ID

285671

Gene namering finger protein 180
SynonymsRINES
Cytomap

5q12.3

Type of geneprotein-coding
DescriptionE3 ubiquitin-protein ligase RNF180RING-type E3 ubiquitin transferase RNF180
Modification date20200313
UniProtAcc

Q86T96,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for RNF180

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1209659(64178028, +), ADediting_1209660(64200332, +), ADediting_1209661(64217768, +), ADediting_1209662(64219584, +), ADediting_1209663(64219595, +), ADediting_1209664(64219608, +), ADediting_1209665(64219653, +), ADediting_1209666(64219656, +), ADediting_1209667(64219721, +), ADediting_1209668(64219787, +), ADediting_1209669(64228241, +), ADediting_1209670(64228258, +), ADediting_1209671(64228259, +), ADediting_1209672(64228391, +), ADediting_1209673(64229022, +), ADediting_1209674(64234208, +), ADediting_1209675(64234263, +), ADediting_1209676(64234278, +), ADediting_1209677(64234279, +), ADediting_1209678(64234398, +), ADediting_1209679(64281678, +), ADediting_1209680(64281698, +), ADediting_1209681(64281720, +), ADediting_1209682(64315623, +), ADediting_1209683(64315624, +), ADediting_1209684(64333202, +), ADediting_1209685(64333214, +), ADediting_1209686(64333226, +), ADediting_1209687(64333241, +), ADediting_1209688(64333242, +), ADediting_1209689(64333247, +), ADediting_1209690(64333255, +), ADediting_1209691(64333295, +), ADediting_1209692(64333303, +), ADediting_1209693(64333304, +), ADediting_1209694(64333307, +), ADediting_1209695(64333317, +), ADediting_1209696(64333339, +), ADediting_1209697(64333347, +), ADediting_1209698(64333350, +), ADediting_1209699(64333355, +), ADediting_1209700(64333358, +), ADediting_1209701(64333367, +), ADediting_1209702(64333413, +), ADediting_1209703(64333432, +), ADediting_1209704(64333433, +), ADediting_1209705(64333445, +), ADediting_1209706(64337055, +), ADediting_1209707(64337063, +), ADediting_1209708(64337101, +), ADediting_1209709(64337109, +), ADediting_1209710(64337113, +), ADediting_1209711(64337118, +), ADediting_1209712(64337126, +), ADediting_1209713(64337131, +), ADediting_1209714(64337143, +), ADediting_1209715(64337153, +), ADediting_1209716(64337155, +), ADediting_1209717(64337193, +), ADediting_1209718(64337199, +), ADediting_1209719(64337207, +), ADediting_1209720(64337210, +), ADediting_1209721(64337238, +), ADediting_1209722(64337270, +), ADediting_1209723(64337271, +), ADediting_1209724(64337277, +), ADediting_1209725(64337283, +), ADediting_1209726(64338379, +), ADediting_1209727(64338380, +), ADediting_1209728(64338385, +), ADediting_1209729(64338386, +), ADediting_1209730(64338406, +), ADediting_1209731(64338457, +), ADediting_1209732(64338514, +), ADediting_1209733(64338520, +), ADediting_1209734(64338524, +), ADediting_1209735(64338528, +), ADediting_1209736(64338541, +), ADediting_1209737(64338576, +), ADediting_1209738(64338618, +), ADediting_1657534(64217691, +), ADediting_1657535(64217771, +), ADediting_1657536(64217896, +), ADediting_1657537(64219655, +), ADediting_1657538(64228403, +), ADediting_1657539(64228434, +), ADediting_1657540(64228458, +), ADediting_1657541(64229021, +), ADediting_1657542(64229048, +), ADediting_1657543(64229051, +), ADediting_1657544(64229057, +), ADediting_1657545(64229058, +), ADediting_1657546(64229061, +), ADediting_1657547(64229063, +), ADediting_1657548(64235008, +), ADediting_1657549(64333409, +),

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RNA editing positional annotations for RNF180 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1209659chr5_64178028_+intronic
ADediting_1209660chr5_64200332_+intronic
ADediting_1209661chr5_64217768_+UTR3
ADediting_1209662chr5_64219584_+intronic
ADediting_1209663chr5_64219595_+intronic
ADediting_1209664chr5_64219608_+intronic
ADediting_1209665chr5_64219653_+intronic
ADediting_1209666chr5_64219656_+intronic
ADediting_1209667chr5_64219721_+intronic
ADediting_1209668chr5_64219787_+intronic
ADediting_1209669chr5_64228241_+intronic
ADediting_1209670chr5_64228258_+intronic
ADediting_1209671chr5_64228259_+intronic
ADediting_1209672chr5_64228391_+intronic
ADediting_1209673chr5_64229022_+intronic
ADediting_1209674chr5_64234208_+intronic
ADediting_1209675chr5_64234263_+intronic
ADediting_1209676chr5_64234278_+intronic
ADediting_1209677chr5_64234279_+intronic
ADediting_1209678chr5_64234398_+intronic
ADediting_1209679chr5_64281678_+intronic
ADediting_1209680chr5_64281698_+intronic
ADediting_1209681chr5_64281720_+intronic
ADediting_1209682chr5_64315623_+intronic
ADediting_1209683chr5_64315624_+intronic
ADediting_1209684chr5_64333202_+intronic
ADediting_1209685chr5_64333214_+intronic
ADediting_1209686chr5_64333226_+intronic
ADediting_1209687chr5_64333241_+intronic
ADediting_1209688chr5_64333242_+intronic
ADediting_1209689chr5_64333247_+intronic
ADediting_1209690chr5_64333255_+intronic
ADediting_1209691chr5_64333295_+intronic
ADediting_1209692chr5_64333303_+intronic
ADediting_1209693chr5_64333304_+intronic
ADediting_1209694chr5_64333307_+intronic
ADediting_1209695chr5_64333317_+intronic
ADediting_1209696chr5_64333339_+intronic
ADediting_1209697chr5_64333347_+intronic
ADediting_1209698chr5_64333350_+intronic
ADediting_1209699chr5_64333355_+intronic
ADediting_1209700chr5_64333358_+intronic
ADediting_1209701chr5_64333367_+intronic
ADediting_1209702chr5_64333413_+intronic
ADediting_1209703chr5_64333432_+intronic
ADediting_1209704chr5_64333433_+intronic
ADediting_1209705chr5_64333445_+intronic
ADediting_1209706chr5_64337055_+intronic
ADediting_1209707chr5_64337063_+intronic
ADediting_1209708chr5_64337101_+intronic
ADediting_1209709chr5_64337109_+intronic
ADediting_1209710chr5_64337113_+intronic
ADediting_1209711chr5_64337118_+intronic
ADediting_1209712chr5_64337126_+intronic
ADediting_1209713chr5_64337131_+intronic
ADediting_1209714chr5_64337143_+intronic
ADediting_1209715chr5_64337153_+intronic
ADediting_1209716chr5_64337155_+intronic
ADediting_1209717chr5_64337193_+intronic
ADediting_1209718chr5_64337199_+intronic
ADediting_1209719chr5_64337207_+intronic
ADediting_1209720chr5_64337210_+intronic
ADediting_1209721chr5_64337238_+intronic
ADediting_1209722chr5_64337270_+intronic
ADediting_1209723chr5_64337271_+intronic
ADediting_1209724chr5_64337277_+intronic
ADediting_1209725chr5_64337283_+intronic
ADediting_1209726chr5_64338379_+intronic
ADediting_1209727chr5_64338380_+intronic
ADediting_1209728chr5_64338385_+intronic
ADediting_1209729chr5_64338386_+intronic
ADediting_1209730chr5_64338406_+intronic
ADediting_1209731chr5_64338457_+intronic
ADediting_1209732chr5_64338514_+intronic
ADediting_1209733chr5_64338520_+intronic
ADediting_1209734chr5_64338524_+intronic
ADediting_1209735chr5_64338528_+intronic
ADediting_1209736chr5_64338541_+intronic
ADediting_1209737chr5_64338576_+intronic
ADediting_1209738chr5_64338618_+intronic
ADediting_1657534chr5_64217691_+UTR3
ADediting_1657535chr5_64217771_+UTR3
ADediting_1657536chr5_64217896_+intronic
ADediting_1657537chr5_64219655_+intronic
ADediting_1657538chr5_64228403_+intronic
ADediting_1657539chr5_64228434_+intronic
ADediting_1657540chr5_64228458_+intronic
ADediting_1657541chr5_64229021_+intronic
ADediting_1657542chr5_64229048_+intronic
ADediting_1657543chr5_64229051_+intronic
ADediting_1657544chr5_64229057_+intronic
ADediting_1657545chr5_64229058_+intronic
ADediting_1657546chr5_64229061_+intronic
ADediting_1657547chr5_64229063_+intronic
ADediting_1657548chr5_64235008_+intronic
ADediting_1657549chr5_64333409_+intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1209659chr5_64178028_+SINEAluName=AluSc5
ADediting_1209660chr5_64200332_+SINEAluName=AluJr
ADediting_1209661chr5_64217768_+SINEAluName=AluJo
ADediting_1209662chr5_64219584_+SINEAluName=AluSc
ADediting_1209663chr5_64219595_+SINEAluName=AluSc
ADediting_1209664chr5_64219608_+SINEAluName=AluSc
ADediting_1209665chr5_64219653_+SINEAluName=AluSc
ADediting_1209666chr5_64219656_+SINEAluName=AluSc
ADediting_1209667chr5_64219721_+SINEAluName=AluSc
ADediting_1209668chr5_64219787_+SINEAluName=AluSc
ADediting_1209669chr5_64228241_+SINEAluName=AluJb
ADediting_1209670chr5_64228258_+SINEAluName=AluJb
ADediting_1209671chr5_64228259_+SINEAluName=AluJb
ADediting_1209672chr5_64228391_+SINEAluName=AluJb
ADediting_1209673chr5_64229022_+SINEAluName=AluJb
ADediting_1209674chr5_64234208_+SINEAluName=AluSz
ADediting_1209675chr5_64234263_+SINEAluName=AluSz
ADediting_1209676chr5_64234278_+SINEAluName=AluSz
ADediting_1209677chr5_64234279_+SINEAluName=AluSz
ADediting_1209678chr5_64234398_+SINEAluName=AluSz
ADediting_1209679chr5_64281678_+SINEAluName=AluSg
ADediting_1209680chr5_64281698_+SINEAluName=AluSg
ADediting_1209681chr5_64281720_+SINEAluName=AluSg
ADediting_1209682chr5_64315623_+SINEAluName=AluSq2
ADediting_1209683chr5_64315624_+SINEAluName=AluSq2
ADediting_1209684chr5_64333202_+SINEAluName=AluSx
ADediting_1209685chr5_64333214_+SINEAluName=AluSx
ADediting_1209686chr5_64333226_+SINEAluName=AluSx
ADediting_1209687chr5_64333241_+SINEAluName=AluSx
ADediting_1209688chr5_64333242_+SINEAluName=AluSx
ADediting_1209689chr5_64333247_+SINEAluName=AluSx
ADediting_1209690chr5_64333255_+SINEAluName=AluSx
ADediting_1209691chr5_64333295_+SINEAluName=AluSx
ADediting_1209692chr5_64333303_+SINEAluName=AluSx
ADediting_1209693chr5_64333304_+SINEAluName=AluSx
ADediting_1209694chr5_64333307_+SINEAluName=AluSx
ADediting_1209695chr5_64333317_+SINEAluName=AluSx
ADediting_1209696chr5_64333339_+SINEAluName=AluSx
ADediting_1209697chr5_64333347_+SINEAluName=AluSx
ADediting_1209698chr5_64333350_+SINEAluName=AluSx
ADediting_1209699chr5_64333355_+SINEAluName=AluSx
ADediting_1209700chr5_64333358_+SINEAluName=AluSx
ADediting_1209701chr5_64333367_+SINEAluName=AluSx
ADediting_1209702chr5_64333413_+SINEAluName=AluSx
ADediting_1209703chr5_64333432_+SINEAluName=AluSx
ADediting_1209704chr5_64333433_+SINEAluName=AluSx
ADediting_1209705chr5_64333445_+SINEAluName=AluSx
ADediting_1209706chr5_64337055_+SINEAluName=AluJr
ADediting_1209707chr5_64337063_+SINEAluName=AluJr
ADediting_1209708chr5_64337101_+SINEAluName=AluJr
ADediting_1209709chr5_64337109_+SINEAluName=AluJr
ADediting_1209710chr5_64337113_+SINEAluName=AluJr
ADediting_1209711chr5_64337118_+SINEAluName=AluJr
ADediting_1209712chr5_64337126_+SINEAluName=AluJr
ADediting_1209713chr5_64337131_+SINEAluName=AluJr
ADediting_1209714chr5_64337143_+SINEAluName=AluJr
ADediting_1209715chr5_64337153_+SINEAluName=AluJr
ADediting_1209716chr5_64337155_+SINEAluName=AluJr
ADediting_1209717chr5_64337193_+SINEAluName=AluJr
ADediting_1209718chr5_64337199_+SINEAluName=AluJr
ADediting_1209719chr5_64337207_+SINEAluName=AluJr
ADediting_1209720chr5_64337210_+SINEAluName=AluJr
ADediting_1209721chr5_64337238_+SINEAluName=AluJr
ADediting_1209722chr5_64337270_+SINEAluName=AluJr
ADediting_1209723chr5_64337271_+SINEAluName=AluJr
ADediting_1209724chr5_64337277_+SINEAluName=AluJr
ADediting_1209725chr5_64337283_+SINEAluName=AluJr
ADediting_1209726chr5_64338379_+SINEAluName=AluY
ADediting_1209727chr5_64338380_+SINEAluName=AluY
ADediting_1209728chr5_64338385_+SINEAluName=AluY
ADediting_1209729chr5_64338386_+SINEAluName=AluY
ADediting_1209730chr5_64338406_+SINEAluName=AluY
ADediting_1209731chr5_64338457_+SINEAluName=AluY
ADediting_1209732chr5_64338514_+SINEAluName=AluY
ADediting_1209733chr5_64338520_+SINEAluName=AluY
ADediting_1209734chr5_64338524_+SINEAluName=AluY
ADediting_1209735chr5_64338528_+SINEAluName=AluY
ADediting_1209736chr5_64338541_+SINEAluName=AluY
ADediting_1209737chr5_64338576_+SINEAluName=AluY
ADediting_1209738chr5_64338618_+SINEAluName=AluY
ADediting_1657534chr5_64217691_+SINEAluName=AluJo
ADediting_1657535chr5_64217771_+SINEAluName=AluJo
ADediting_1657536chr5_64217896_+SINEAluName=AluJo
ADediting_1657537chr5_64219655_+SINEAluName=AluSc
ADediting_1657538chr5_64228403_+SINEAluName=AluJb
ADediting_1657539chr5_64228434_+SINEAluName=AluJb
ADediting_1657540chr5_64228458_+SINEAluName=AluJb
ADediting_1657541chr5_64229021_+SINEAluName=AluJb
ADediting_1657542chr5_64229048_+SINEAluName=AluJb
ADediting_1657543chr5_64229051_+SINEAluName=AluJb
ADediting_1657544chr5_64229057_+SINEAluName=AluJb
ADediting_1657545chr5_64229058_+SINEAluName=AluJb
ADediting_1657546chr5_64229061_+SINEAluName=AluJb
ADediting_1657547chr5_64229063_+SINEAluName=AluJb
ADediting_1657548chr5_64235008_+SINEAluName=AluJb
ADediting_1657549chr5_64333409_+SINEAluName=AluSx

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RNA A-to-I editing events in the alternative splicing sites for RNF180

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for RNF180

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for RNF180

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for RNF180

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1209661chr5_64217768_+ENSG00000164197.12ENST00000296615.10RNF180-201hsa-miR-4659a-5pchr564217764642177718mer-1a6421775064217771145-14.33
ADediting_1209661chr5_64217768_+ENSG00000164197.12ENST00000296615.10RNF180-201hsa-miR-4659b-5pchr564217764642177718mer-1a6421775364217771145-14.91
ADediting_1209661chr5_64217768_+ENSG00000164197.12ENST00000296615.10RNF180-201hsa-miR-4716-5pchr564217762642177687mer-m86421774864217769148-13.48
ADediting_1209661chr5_64217768_+ENSG00000164197.12ENST00000296615.10RNF180-201hsa-miR-4776-3pchr564217765642177728mer-1a6421774964217772153-18.04
ADediting_1657534chr5_64217691_+ENSG00000164197.12ENST00000296615.10RNF180-201hsa-miR-10399-5pchr564217688642176947mer-m86421767564217695146-10.94
ADediting_1657534chr5_64217691_+ENSG00000164197.12ENST00000296615.10RNF180-201hsa-miR-6504-3pchr564217688642176947mer-m86421767564217695146-11.61

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1657535chr5_64217771_+ENSG00000164197.12ENST00000296615.10RNF180-201hsa-miR-19b-1-5pchr564217768642177747mer-m86421775564217775154-16.4
ADediting_1657535chr5_64217771_+ENSG00000164197.12ENST00000296615.10RNF180-201hsa-miR-19b-2-5pchr564217768642177747mer-m86421775464217775152-11.4

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_843620chr2_207754818_+ENSG00000164197.12ENST00000389100.9RNF180-202hsa-miR-4775chr564372380643723867mer-m86437236564372387164-14.2
ADediting_98289chr1_32086992_+ENSG00000164197.12ENST00000296615.10RNF180-201hsa-miR-5585-3pchr564217542642175487mer-1a6421752764217548144-14.36
ADediting_98289chr1_32086992_+ENSG00000164197.12ENST00000389100.9RNF180-202hsa-miR-5585-3pchr564371914643719218mer-1a6437189664371921154-19.19

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1391023chr8_140732605_-ENSG00000164197.12ENST00000389100.9RNF180-202hsa-miR-151a-3pchr564371589643715957mer-m86437157764371596153-13.57
ADediting_1471003chr9_63819626_+ENSG00000164197.12ENST00000296615.10RNF180-201hsa-miR-4477bchr564217591642175977mer-m86421757864217598146-7.61
ADediting_1471004chr9_63819627_+ENSG00000164197.12ENST00000296615.10RNF180-201hsa-miR-4477bchr564217591642175977mer-m86421757864217598146-7.61
ADediting_1556067chr19_40282625_-ENSG00000164197.12ENST00000389100.9RNF180-202hsa-miR-641chr564372555643725617mer-m86437253764372562148-9.96
ADediting_1631458chr19_40282624_-ENSG00000164197.12ENST00000389100.9RNF180-202hsa-miR-641chr564372555643725617mer-m86437253764372562148-9.96
ADediting_286380chr11_79422188_-ENSG00000164197.12ENST00000389100.9RNF180-202hsa-miR-5579-3pchr564371049643710568mer-1a6437103564371056146-10.86
ADediting_843620chr2_207754818_+ENSG00000164197.12ENST00000389100.9RNF180-202hsa-miR-4775chr564371743643717497mer-m86437172764371750150-4.88

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for RNF180

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000296615.10protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_1657534ENST00000296615.10chr5_64217691_+1632-507.20-505.10-507.60
ADediting_1209661ENST00000296615.10chr5_64217768_+1709-504.80-505.10-507.60
ADediting_1657535ENST00000296615.10chr5_64217771_+1712-504.80-505.10-507.60

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for RNF180

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_1209712chr5_64337126_+0.230831982932950.06825057019093140.367483757017258-0.05135821972416241.02401756081486e-170.460988153337646
DLPFCADediting_1209732chr5_64338514_+0.2927801826406430.05994038654455930.580682157233984-0.03149300350995285.16579247644954e-110.361688319944928
DLPFCADediting_1209735chr5_64338528_+0.3098792988723090.05786053399682560.0669746186586943-0.1041793499102369.70095192446151e-120.374199063677303
DLPFCADediting_1209736chr5_64338541_+0.1023655817660840.09295065036963780.362799687481159-0.05186170225357364.82039747064291e-100.344083736997313

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC9.4354258004218e-180.4614365318567914.84169240379926e-070.2811747272142490.109755794688296-0.0910127280674705
AC2.81774659224484e-520.7794116894588152.21596610819077e-390.7082795556324354.37187205954356e-090.360469581356423
PCC1.11647077218249e-290.7020503859529111.13498411606226e-220.63175572749443.05954401190899e-060.330318015696191
CER3.91531199666513e-260.7289465248606995.96455805727132e-120.523949705126890.004118095351588980.232967324112372
TCX8.7674842369588e-430.848697578278283.59916524055971e-180.6330074033035150.4837287198590760.0576151808967894
FP5.07729027418381e-250.6749979235850078.10119880038683e-350.7603700213739240.1271413532403550.114769406953363
IFG1.09521624710521e-070.8447012386168464.1119587536524e-060.7808475764021710.8018602152674420.0528592350455756
PG2.07519618651182e-590.8734537736108791.25581747003366e-360.7624386819447610.265326758743729-0.0820897770114502
STG8.02406917922132e-230.8333839931882261.0458465298899e-180.7846364734570920.4278168508861840.0876628741494666

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Relation with AD stages for RNF180

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
TCX0.0004546190141245290.334642764052986

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RelatedDrugs for RNF180

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for RNF180

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource