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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for FAM182A |
 Gene summary |
| Gene information | Gene symbol | FAM182A | Gene ID | 284800 |
| Gene name | family with sequence similarity 182 member A | |
| Synonyms | C20orf91|C20orf91A | |
| Cytomap | 20p11.1 | |
| Type of gene | ncRNA | |
| Description | - | |
| Modification date | 20200313 | |
| UniProtAcc | Q5T1J6, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for FAM182A |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_916676(25995874, +), ADediting_916677(25995900, +), ADediting_916678(25999317, +), ADediting_916679(26006782, +), ADediting_916680(26006995, +), ADediting_916681(26007005, +), ADediting_916682(26007606, +), ADediting_916683(26007609, +), ADediting_916684(26007610, +), ADediting_916685(26007635, +), ADediting_916686(26007715, +), ADediting_916687(26007735, +), ADediting_916688(26007740, +), ADediting_916689(26007744, +), ADediting_916690(26007745, +), ADediting_916691(26007758, +), ADediting_916692(26007774, +), ADediting_916693(26008063, +), ADediting_916694(26008485, +), ADediting_916695(26008486, +), ADediting_916696(26008506, +), ADediting_916697(26008523, +), ADediting_916698(26008527, +), ADediting_916699(26008549, +), ADediting_916700(26008550, +), ADediting_916701(26008555, +), ADediting_916702(26008559, +), ADediting_916703(26015492, +), ADediting_916704(26015551, +), ADediting_916705(26015552, +), ADediting_916706(26015556, +), ADediting_916713(26083283, +), ADediting_916714(26083493, +), ADediting_916715(26083571, +), ADediting_916716(26083600, +), ADediting_916717(26083615, +), ADediting_916718(26083662, +), ADediting_916719(26083698, +), ADediting_916720(26083699, +), ADediting_916721(26083713, +), ADediting_916722(26083717, +), ADediting_916723(26083735, +), ADediting_916724(26083764, +), ADediting_916725(26083779, +), ADediting_916726(26083943, +), ADediting_916727(26084013, +), ADediting_1565486(26000659, +), ADediting_1565487(26008541, +), |
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RNA editing positional annotations for FAM182A using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_916676 | chr20_25995874_+ | ncRNA_intronic |
| ADediting_916677 | chr20_25995900_+ | ncRNA_intronic |
| ADediting_916678 | chr20_25999317_+ | ncRNA_intronic |
| ADediting_916679 | chr20_26006782_+ | ncRNA_intronic |
| ADediting_916680 | chr20_26006995_+ | ncRNA_intronic |
| ADediting_916681 | chr20_26007005_+ | ncRNA_intronic |
| ADediting_916682 | chr20_26007606_+ | ncRNA_intronic |
| ADediting_916683 | chr20_26007609_+ | ncRNA_intronic |
| ADediting_916684 | chr20_26007610_+ | ncRNA_intronic |
| ADediting_916685 | chr20_26007635_+ | ncRNA_intronic |
| ADediting_916686 | chr20_26007715_+ | ncRNA_intronic |
| ADediting_916687 | chr20_26007735_+ | ncRNA_intronic |
| ADediting_916688 | chr20_26007740_+ | ncRNA_intronic |
| ADediting_916689 | chr20_26007744_+ | ncRNA_intronic |
| ADediting_916690 | chr20_26007745_+ | ncRNA_intronic |
| ADediting_916691 | chr20_26007758_+ | ncRNA_intronic |
| ADediting_916692 | chr20_26007774_+ | ncRNA_intronic |
| ADediting_916693 | chr20_26008063_+ | ncRNA_intronic |
| ADediting_916694 | chr20_26008485_+ | ncRNA_intronic |
| ADediting_916695 | chr20_26008486_+ | ncRNA_intronic |
| ADediting_916696 | chr20_26008506_+ | ncRNA_intronic |
| ADediting_916697 | chr20_26008523_+ | ncRNA_intronic |
| ADediting_916698 | chr20_26008527_+ | ncRNA_intronic |
| ADediting_916699 | chr20_26008549_+ | ncRNA_intronic |
| ADediting_916700 | chr20_26008550_+ | ncRNA_intronic |
| ADediting_916701 | chr20_26008555_+ | ncRNA_intronic |
| ADediting_916702 | chr20_26008559_+ | ncRNA_intronic |
| ADediting_916703 | chr20_26015492_+ | ncRNA_intronic |
| ADediting_916704 | chr20_26015551_+ | ncRNA_intronic |
| ADediting_916705 | chr20_26015552_+ | ncRNA_intronic |
| ADediting_916706 | chr20_26015556_+ | ncRNA_intronic |
| ADediting_916713 | chr20_26083283_+ | ncRNA_exonic |
| ADediting_916714 | chr20_26083493_+ | ncRNA_exonic |
| ADediting_916715 | chr20_26083571_+ | ncRNA_exonic |
| ADediting_916716 | chr20_26083600_+ | ncRNA_exonic |
| ADediting_916717 | chr20_26083615_+ | ncRNA_exonic |
| ADediting_916718 | chr20_26083662_+ | ncRNA_exonic |
| ADediting_916719 | chr20_26083698_+ | ncRNA_exonic |
| ADediting_916720 | chr20_26083699_+ | ncRNA_exonic |
| ADediting_916721 | chr20_26083713_+ | ncRNA_exonic |
| ADediting_916722 | chr20_26083717_+ | ncRNA_exonic |
| ADediting_916723 | chr20_26083735_+ | ncRNA_exonic |
| ADediting_916724 | chr20_26083764_+ | ncRNA_exonic |
| ADediting_916725 | chr20_26083779_+ | ncRNA_exonic |
| ADediting_916726 | chr20_26083943_+ | ncRNA_exonic |
| ADediting_916727 | chr20_26084013_+ | ncRNA_exonic |
| ADediting_1565486 | chr20_26000659_+ | ncRNA_intronic |
| ADediting_1565487 | chr20_26008541_+ | ncRNA_intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_916676 | chr20_25995874_+ | SINE | Alu | Name=AluSz |
| ADediting_916677 | chr20_25995900_+ | SINE | Alu | Name=AluSz |
| ADediting_916678 | chr20_25999317_+ | SINE | Alu | Name=AluSx1 |
| ADediting_916679 | chr20_26006782_+ | SINE | Alu | Name=AluSz |
| ADediting_916680 | chr20_26006995_+ | SINE | Alu | Name=AluSz |
| ADediting_916681 | chr20_26007005_+ | SINE | Alu | Name=AluSz |
| ADediting_916682 | chr20_26007606_+ | SINE | Alu | Name=AluSx3 |
| ADediting_916683 | chr20_26007609_+ | SINE | Alu | Name=AluSx3 |
| ADediting_916684 | chr20_26007610_+ | SINE | Alu | Name=AluSx3 |
| ADediting_916685 | chr20_26007635_+ | SINE | Alu | Name=AluSx3 |
| ADediting_916686 | chr20_26007715_+ | SINE | Alu | Name=AluSx3 |
| ADediting_916687 | chr20_26007735_+ | SINE | Alu | Name=AluSx3 |
| ADediting_916688 | chr20_26007740_+ | SINE | Alu | Name=AluSx3 |
| ADediting_916689 | chr20_26007744_+ | SINE | Alu | Name=AluSx3 |
| ADediting_916690 | chr20_26007745_+ | SINE | Alu | Name=AluSx3 |
| ADediting_916691 | chr20_26007758_+ | SINE | Alu | Name=AluSx3 |
| ADediting_916692 | chr20_26007774_+ | SINE | Alu | Name=AluSx3 |
| ADediting_916693 | chr20_26008063_+ | SINE | Alu | Name=AluSx |
| ADediting_916694 | chr20_26008485_+ | SINE | Alu | Name=AluSx |
| ADediting_916695 | chr20_26008486_+ | SINE | Alu | Name=AluSx |
| ADediting_916696 | chr20_26008506_+ | SINE | Alu | Name=AluSx |
| ADediting_916697 | chr20_26008523_+ | SINE | Alu | Name=AluSx |
| ADediting_916698 | chr20_26008527_+ | SINE | Alu | Name=AluSx |
| ADediting_916699 | chr20_26008549_+ | SINE | Alu | Name=AluSx |
| ADediting_916700 | chr20_26008550_+ | SINE | Alu | Name=AluSx |
| ADediting_916701 | chr20_26008555_+ | SINE | Alu | Name=AluSx |
| ADediting_916702 | chr20_26008559_+ | SINE | Alu | Name=AluSx |
| ADediting_916703 | chr20_26015492_+ | SINE | Alu | Name=AluSz6 |
| ADediting_916704 | chr20_26015551_+ | SINE | Alu | Name=AluSz6 |
| ADediting_916705 | chr20_26015552_+ | SINE | Alu | Name=AluSz6 |
| ADediting_916706 | chr20_26015556_+ | SINE | Alu | Name=AluSz6 |
| ADediting_1565486 | chr20_26000659_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1565487 | chr20_26008541_+ | SINE | Alu | Name=AluSx |
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RNA A-to-I editing events in the alternative splicing sites for FAM182A |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for FAM182A |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for FAM182A |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for FAM182A |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_916713 | chr20_26083283_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-1226-3p | chr20 | 26083280 | 26083286 | 7mer-m8 | 26083266 | 26083287 | 156 | -20.97 |
| ADediting_916713 | chr20_26083283_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-122b-3p | chr20 | 26083282 | 26083288 | 7mer-m8 | 26083268 | 26083289 | 146 | -12.28 |
| ADediting_916713 | chr20_26083283_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-21-3p | chr20 | 26083282 | 26083288 | 7mer-m8 | 26083269 | 26083289 | 155 | -20.42 |
| ADediting_916715 | chr20_26083571_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-516b-5p | chr20 | 26083566 | 26083572 | 7mer-m8 | 26083552 | 26083573 | 140 | -14.96 |
| ADediting_916716 | chr20_26083600_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-6765-3p | chr20 | 26083594 | 26083600 | 7mer-m8 | 26083578 | 26083601 | 143 | -20.79 |
| ADediting_916717 | chr20_26083615_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-378j | chr20 | 26083609 | 26083616 | 8mer-1a | 26083598 | 26083616 | 144 | -12.4 |
| ADediting_916717 | chr20_26083615_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-4782-5p | chr20 | 26083610 | 26083616 | 7mer-m8 | 26083595 | 26083617 | 151 | -11.61 |
| ADediting_916717 | chr20_26083615_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-5706 | chr20 | 26083610 | 26083616 | 7mer-m8 | 26083594 | 26083617 | 147 | -14.78 |
| ADediting_916717 | chr20_26083615_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-6839-5p | chr20 | 26083609 | 26083616 | 8mer-1a | 26083595 | 26083616 | 156 | -16.67 |
| ADediting_916720 | chr20_26083699_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-2861 | chr20 | 26083697 | 26083703 | 7mer-m8 | 26083686 | 26083704 | 143 | -23.01 |
| ADediting_916724 | chr20_26083764_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-500b-3p | chr20 | 26083758 | 26083764 | 7mer-m8 | 26083745 | 26083765 | 149 | -18.97 |
| ADediting_916726 | chr20_26083943_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-659-5p | chr20 | 26083941 | 26083947 | 7mer-m8 | 26083927 | 26083948 | 140 | -16.71 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_916713 | chr20_26083283_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-4704-5p | chr20 | 26083281 | 26083287 | 7mer-m8 | 26083267 | 26083288 | 152 | -15.41 |
| ADediting_916714 | chr20_26083493_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-4436b-5p | chr20 | 26083492 | 26083498 | 7mer-m8 | 26083477 | 26083499 | 150 | -22.39 |
| ADediting_916717 | chr20_26083615_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-5004-3p | chr20 | 26083609 | 26083616 | 8mer-1a | 26083595 | 26083616 | 146 | -14.32 |
| ADediting_916718 | chr20_26083662_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-622 | chr20 | 26083661 | 26083667 | 7mer-m8 | 26083648 | 26083668 | 147 | -13.54 |
| ADediting_916721 | chr20_26083713_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-331-5p | chr20 | 26083711 | 26083717 | 7mer-m8 | 26083697 | 26083718 | 152 | -21.61 |
| ADediting_916722 | chr20_26083717_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-331-5p | chr20 | 26083711 | 26083717 | 7mer-m8 | 26083697 | 26083718 | 152 | -21.61 |
| ADediting_916722 | chr20_26083717_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-6503-3p | chr20 | 26083715 | 26083721 | 7mer-m8 | 26083703 | 26083722 | 155 | -24.12 |
| ADediting_916723 | chr20_26083735_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-2861 | chr20 | 26083734 | 26083740 | 7mer-m8 | 26083723 | 26083741 | 141 | -21.1 |
| ADediting_916725 | chr20_26083779_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-3622a-3p | chr20 | 26083777 | 26083783 | 7mer-m8 | 26083763 | 26083784 | 140 | -15.47 |
| ADediting_916725 | chr20_26083779_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-3622b-3p | chr20 | 26083777 | 26083783 | 7mer-m8 | 26083764 | 26083784 | 148 | -19.95 |
| ADediting_916725 | chr20_26083779_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-4649-3p | chr20 | 26083774 | 26083780 | 7mer-m8 | 26083759 | 26083781 | 150 | -26.14 |
| ADediting_916725 | chr20_26083779_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-544b | chr20 | 26083775 | 26083781 | 7mer-m8 | 26083762 | 26083782 | 150 | -20.07 |
| ADediting_916726 | chr20_26083943_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-8083 | chr20 | 26083942 | 26083948 | 7mer-m8 | 26083929 | 26083949 | 143 | -14.65 |
| ADediting_916727 | chr20_26084013_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-7152-3p | chr20 | 26084008 | 26084015 | 8mer-1a | 26083992 | 26084015 | 149 | -28.1 |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-589-3p | chr20 | 26054785 | 26054792 | 8mer-1a | 26054768 | 26054792 | 153 | -18.56 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000125804.14 | ENST00000653942.1 | FAM182A-208 | hsa-miR-589-3p | chr20 | 25988410 | 25988416 | 7mer-m8 | 25988394 | 25988417 | 158 | -24.55 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000125804.14 | ENST00000653942.1 | FAM182A-208 | hsa-miR-589-3p | chr20 | 25988410 | 25988416 | 7mer-m8 | 25988410 | 25988434 | 147 | -17.85 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000125804.14 | ENST00000653942.1 | FAM182A-208 | hsa-miR-589-3p | chr20 | 25988427 | 25988433 | 7mer-m8 | 25988410 | 25988434 | 147 | -17.85 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000125804.14 | ENST00000653942.1 | FAM182A-208 | hsa-miR-589-3p | chr20 | 25988966 | 25988972 | 7mer-m8 | 25988950 | 25988973 | 152 | -15.72 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000125804.14 | ENST00000667959.1 | FAM182A-215 | hsa-miR-589-3p | chr20 | 25986204 | 25986210 | 7mer-m8 | 25986188 | 25986211 | 145 | -17.01 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000125804.14 | ENST00000667959.1 | FAM182A-215 | hsa-miR-589-3p | chr20 | 25986244 | 25986250 | 7mer-m8 | 25986228 | 25986251 | 150 | -15.97 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000125804.14 | ENST00000653942.1 | FAM182A-208 | hsa-miR-151a-3p | chr20 | 25988503 | 25988509 | 7mer-m8 | 25988486 | 25988510 | 148 | -13.48 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000125804.14 | ENST00000471057.2 | FAM182A-204 | hsa-miR-337-3p | chr20 | 26076427 | 26076434 | 8mer-1a | 26076413 | 26076434 | 163 | -18.04 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000125804.14 | ENST00000652966.1 | FAM182A-206 | hsa-miR-337-3p | chr20 | 26076427 | 26076434 | 8mer-1a | 26076413 | 26076434 | 163 | -18.04 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000125804.14 | ENST00000656743.1 | FAM182A-209 | hsa-miR-337-3p | chr20 | 26076427 | 26076434 | 8mer-1a | 26076413 | 26076434 | 163 | -18.04 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000125804.14 | ENST00000657899.1 | FAM182A-210 | hsa-miR-337-3p | chr20 | 26076427 | 26076434 | 8mer-1a | 26076413 | 26076434 | 163 | -18.04 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000125804.14 | ENST00000670372.1 | FAM182A-217 | hsa-miR-337-3p | chr20 | 26076427 | 26076434 | 8mer-1a | 26076413 | 26076434 | 163 | -18.04 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000125804.14 | ENST00000670756.1 | FAM182A-218 | hsa-miR-337-3p | chr20 | 26076427 | 26076434 | 8mer-1a | 26076413 | 26076434 | 163 | -18.04 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000125804.14 | ENST00000389261.4 | FAM182A-202 | hsa-miR-641 | chr20 | 26057485 | 26057491 | 7mer-m8 | 26057469 | 26057492 | 140 | -18.33 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000125804.14 | ENST00000482133.2 | FAM182A-205 | hsa-miR-641 | chr20 | 26057485 | 26057491 | 7mer-m8 | 26057469 | 26057492 | 140 | -18.33 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000125804.14 | ENST00000652966.1 | FAM182A-206 | hsa-miR-641 | chr20 | 26057485 | 26057491 | 7mer-m8 | 26057469 | 26057492 | 140 | -18.33 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000125804.14 | ENST00000656743.1 | FAM182A-209 | hsa-miR-641 | chr20 | 26057485 | 26057491 | 7mer-m8 | 26057469 | 26057492 | 140 | -18.33 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000125804.14 | ENST00000660813.1 | FAM182A-211 | hsa-miR-641 | chr20 | 26057485 | 26057491 | 7mer-m8 | 26057469 | 26057492 | 140 | -18.33 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000125804.14 | ENST00000666563.1 | FAM182A-213 | hsa-miR-641 | chr20 | 26057485 | 26057491 | 7mer-m8 | 26057469 | 26057492 | 140 | -18.33 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000125804.14 | ENST00000667322.1 | FAM182A-214 | hsa-miR-641 | chr20 | 26052162 | 26052168 | 7mer-m8 | 26052146 | 26052169 | 153 | -17.67 |
| ADediting_496066 | chr15_66496985_- | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-4512 | chr20 | 26083543 | 26083550 | 8mer-1a | 26083526 | 26083550 | 142 | -24.25 |
| ADediting_496066 | chr15_66496985_- | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-4512 | chr20 | 26083625 | 26083632 | 8mer-1a | 26083611 | 26083632 | 140 | -16.21 |
| ADediting_496066 | chr15_66496985_- | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-4512 | chr20 | 26083735 | 26083742 | 8mer-1a | 26083723 | 26083742 | 152 | -21.89 |
| ADediting_496066 | chr15_66496985_- | ENSG00000125804.14 | ENST00000653942.1 | FAM182A-208 | hsa-miR-4512 | chr20 | 25988345 | 25988351 | 7mer-m8 | 25988331 | 25988352 | 149 | -18.13 |
| ADediting_496066 | chr15_66496985_- | ENSG00000125804.14 | ENST00000667322.1 | FAM182A-214 | hsa-miR-4512 | chr20 | 26052405 | 26052412 | 8mer-1a | 26052395 | 26052412 | 143 | -21.37 |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-589-3p | chr20 | 26086861 | 26086867 | 7mer-m8 | 26086841 | 26086868 | 155 | -20.43 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-641 | chr20 | 26084988 | 26084994 | 7mer-m8 | 26084972 | 26084995 | 140 | -17.56 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000125804.14 | ENST00000653942.1 | FAM182A-208 | hsa-miR-641 | chr20 | 25988479 | 25988485 | 7mer-m8 | 25988462 | 25988486 | 151 | -13.27 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000125804.14 | ENST00000667959.1 | FAM182A-215 | hsa-miR-641 | chr20 | 25986256 | 25986262 | 7mer-m8 | 25986239 | 25986263 | 155 | -15.23 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-641 | chr20 | 26084988 | 26084994 | 7mer-m8 | 26084972 | 26084995 | 140 | -17.56 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000125804.14 | ENST00000653942.1 | FAM182A-208 | hsa-miR-641 | chr20 | 25988479 | 25988485 | 7mer-m8 | 25988462 | 25988486 | 151 | -13.27 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000125804.14 | ENST00000667959.1 | FAM182A-215 | hsa-miR-641 | chr20 | 25986256 | 25986262 | 7mer-m8 | 25986239 | 25986263 | 155 | -15.23 |
| ADediting_496066 | chr15_66496985_- | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-4512 | chr20 | 26083465 | 26083472 | 8mer-1a | 26083453 | 26083472 | 153 | -21.3 |
| ADediting_496066 | chr15_66496985_- | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-4512 | chr20 | 26083826 | 26083833 | 8mer-1a | 26083812 | 26083833 | 140 | -19.51 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000125804.14 | ENST00000376398.6 | FAM182A-201 | hsa-miR-4775 | chr20 | 26054805 | 26054812 | 8mer-1a | 26054791 | 26054812 | 140 | -8.98 |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for FAM182A |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000376398.6 | lncRNA |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_916713 | ENST00000376398.6 | chr20_26083283_+ | 1436 | -2127.90 | -2124.60 | -2146.80 |
| ADediting_916714 | ENST00000376398.6 | chr20_26083493_+ | 1646 | -2124.30 | -2124.60 | -2146.80 |
| ADediting_916715 | ENST00000376398.6 | chr20_26083571_+ | 1724 | -2124.60 | -2124.60 | -2146.80 |
| ADediting_916716 | ENST00000376398.6 | chr20_26083600_+ | 1753 | -2131.20 | -2124.60 | -2146.80 |
| ADediting_916717 | ENST00000376398.6 | chr20_26083615_+ | 1768 | -2124.70 | -2124.60 | -2146.80 |
| ADediting_916718 | ENST00000376398.6 | chr20_26083662_+ | 1815 | -2123.90 | -2124.60 | -2146.80 |
| ADediting_916719 | ENST00000376398.6 | chr20_26083698_+ | 1851 | -2124.30 | -2124.60 | -2146.80 |
| ADediting_916720 | ENST00000376398.6 | chr20_26083699_+ | 1852 | -2124.30 | -2124.60 | -2146.80 |
| ADediting_916721 | ENST00000376398.6 | chr20_26083713_+ | 1866 | -2124.30 | -2124.60 | -2146.80 |
| ADediting_916722 | ENST00000376398.6 | chr20_26083717_+ | 1870 | -2124.30 | -2124.60 | -2146.80 |
| ADediting_916723 | ENST00000376398.6 | chr20_26083735_+ | 1888 | -2124.60 | -2124.60 | -2146.80 |
| ADediting_916724 | ENST00000376398.6 | chr20_26083764_+ | 1917 | -2131.20 | -2124.60 | -2146.80 |
| ADediting_916725 | ENST00000376398.6 | chr20_26083779_+ | 1932 | -2130.80 | -2124.60 | -2146.80 |
| ADediting_916726 | ENST00000376398.6 | chr20_26083943_+ | 2096 | -2125.60 | -2124.60 | -2146.80 |
| ADediting_916727 | ENST00000376398.6 | chr20_26084013_+ | 2166 | -2125.70 | -2124.60 | -2146.80 |
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Relation with ADAR for FAM182A |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_916717 | chr20_26083615_+ | 0.0163696381898224 | 0.13625709037422 | 0.622094216164527 | 0.0281019527530173 | 3.15662523282688e-13 | 0.398264542728007 |
| DLPFC | ADediting_916720 | chr20_26083699_+ | 0.00194498936937046 | 0.175326497749421 | 0.0285846923609929 | 0.124355695309251 | 2.4916717653432e-11 | 0.367209023756955 |
| DLPFC | ADediting_916722 | chr20_26083717_+ | 3.28839462310358e-05 | 0.233521548150622 | 0.0125995138411774 | 0.141557998540546 | 2.53143141073543e-14 | 0.414822205452223 |
| DLPFC | ADediting_916723 | chr20_26083735_+ | 0.000549832633609483 | 0.195141997186723 | 0.0357157404758257 | 0.119335970503512 | 2.30821990055884e-12 | 0.384526736819096 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 4.72448966010706e-10 | 0.344247113276862 | 0.000440404780310985 | 0.198429360598058 | 9.32535461196029e-15 | 0.421130640688125 |
| AC | 2.82398776215786e-23 | 0.573638375324166 | 1.11076695321766e-13 | 0.446961695769634 | 1.83403333440135e-13 | 0.443375979098614 |
| PCC | 2.4397284891569e-06 | 0.333408163659876 | 0.000410616096168904 | 0.253135999435371 | 5.17547662763857e-07 | 0.353722663380448 |
| CER | 5.52006262531986e-21 | 0.671211039924335 | 1.76406353666597e-16 | 0.607188290103771 | 0.0288049569797626 | 0.178554757602615 |
| TCX | 5.05742686245168e-06 | 0.36278172131049 | 0.485192008949982 | 0.0574228470216358 | 3.40953730961292e-08 | 0.4319325607099 |
| FP | 2.44052945727404e-09 | 0.428397088206976 | 2.84718371523882e-08 | 0.401245023319246 | 2.65397337180323e-08 | 0.402056246408919 |
| IFG | 0.00979451273027902 | 0.506389854295765 | 0.00831098575233999 | 0.515798439481299 | 0.000338767753332228 | 0.659170357679396 |
| PG | 6.82418751858601e-25 | 0.662731789426751 | 2.9015822176079e-13 | 0.501957018287524 | 0.22730032741694 | 0.0889506852563723 |
| STG | 0.0425135462918221 | 0.221880581721425 | 0.047686319668293 | 0.216724590141186 | 9.15904119364054e-06 | 0.463136422793126 |
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Relation with AD stages for FAM182A |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_916678 | chr20_25999317_+ | 0.00152459162780626 | -0.301410452075041 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| TCX | 3.13166657406421e-07 | 0.472619595498993 |
| IFG | 0.0108006632133903 | 0.500663059896889 |
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RelatedDrugs for FAM182A |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for FAM182A |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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