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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

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Relation with AD stages

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Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for ZNF776

check button Gene summary
Gene informationGene symbol

ZNF776

Gene ID

284309

Gene namezinc finger protein 776
Synonyms-
Cytomap

19q13.43

Type of geneprotein-coding
Descriptionzinc finger protein 776
Modification date20200313
UniProtAcc

Q68DI1,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for ZNF776

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_785830(57749033, +), ADediting_785831(57749181, +), ADediting_785832(57749232, +), ADediting_785833(57749238, +), ADediting_785834(57750169, +), ADediting_785835(57750174, +), ADediting_785836(57750214, +), ADediting_785837(57750217, +), ADediting_785838(57750229, +), ADediting_785839(57750240, +), ADediting_785840(57750242, +), ADediting_785841(57750246, +), ADediting_785842(57750247, +), ADediting_785843(57750248, +), ADediting_785844(57750287, +), ADediting_785845(57750312, +), ADediting_785846(57750333, +), ADediting_785847(57750334, +), ADediting_785848(57750339, +), ADediting_785849(57750344, +), ADediting_785850(57750357, +), ADediting_785851(57750360, +), ADediting_785852(57750364, +), ADediting_785853(57750373, +), ADediting_785854(57750387, +), ADediting_785855(57750411, +), ADediting_785856(57750422, +), ADediting_785857(57750445, +), ADediting_785858(57756906, +), ADediting_785859(57756938, +), ADediting_785860(57756953, +), ADediting_785861(57756987, +), ADediting_785862(57757017, +), ADediting_785863(57757019, +), ADediting_785864(57757021, +), ADediting_785865(57757047, +), ADediting_785866(57757058, +), ADediting_785867(57757071, +), ADediting_785868(57757075, +), ADediting_785869(57757104, +), ADediting_785870(57757110, +), ADediting_785871(57757722, +), ADediting_785872(57757731, +), ADediting_785873(57757750, +), ADediting_1559374(57753209, +), ADediting_1559375(57756870, +),

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RNA editing positional annotations for ZNF776 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_785830chr19_57749033_+intronic
ADediting_785831chr19_57749181_+intronic
ADediting_785832chr19_57749232_+intronic
ADediting_785833chr19_57749238_+intronic
ADediting_785834chr19_57750169_+intronic
ADediting_785835chr19_57750174_+intronic
ADediting_785836chr19_57750214_+intronic
ADediting_785837chr19_57750217_+intronic
ADediting_785838chr19_57750229_+intronic
ADediting_785839chr19_57750240_+intronic
ADediting_785840chr19_57750242_+intronic
ADediting_785841chr19_57750246_+intronic
ADediting_785842chr19_57750247_+intronic
ADediting_785843chr19_57750248_+intronic
ADediting_785844chr19_57750287_+intronic
ADediting_785845chr19_57750312_+intronic
ADediting_785846chr19_57750333_+intronic
ADediting_785847chr19_57750334_+intronic
ADediting_785848chr19_57750339_+intronic
ADediting_785849chr19_57750344_+intronic
ADediting_785850chr19_57750357_+intronic
ADediting_785851chr19_57750360_+intronic
ADediting_785852chr19_57750364_+intronic
ADediting_785853chr19_57750373_+intronic
ADediting_785854chr19_57750387_+intronic
ADediting_785855chr19_57750411_+intronic
ADediting_785856chr19_57750422_+intronic
ADediting_785857chr19_57750445_+intronic
ADediting_785858chr19_57756906_+UTR3
ADediting_785859chr19_57756938_+UTR3
ADediting_785860chr19_57756953_+UTR3
ADediting_785861chr19_57756987_+UTR3
ADediting_785862chr19_57757017_+UTR3
ADediting_785863chr19_57757019_+UTR3
ADediting_785864chr19_57757021_+UTR3
ADediting_785865chr19_57757047_+UTR3
ADediting_785866chr19_57757058_+UTR3
ADediting_785867chr19_57757071_+UTR3
ADediting_785868chr19_57757075_+UTR3
ADediting_785869chr19_57757104_+UTR3
ADediting_785870chr19_57757110_+UTR3
ADediting_785871chr19_57757722_+UTR3
ADediting_785872chr19_57757731_+UTR3
ADediting_785873chr19_57757750_+UTR3
ADediting_1559374chr19_57753209_+intronic
ADediting_1559375chr19_57756870_+splicing

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_785830chr19_57749033_+SINEAluName=AluSx3
ADediting_785831chr19_57749181_+SINEAluName=AluSx3
ADediting_785832chr19_57749232_+SINEAluName=AluSx3
ADediting_785833chr19_57749238_+SINEAluName=AluSx3
ADediting_785834chr19_57750169_+SINEAluName=AluSq2
ADediting_785835chr19_57750174_+SINEAluName=AluSq2
ADediting_785836chr19_57750214_+SINEAluName=AluSq2
ADediting_785837chr19_57750217_+SINEAluName=AluSq2
ADediting_785838chr19_57750229_+SINEAluName=AluSq2
ADediting_785839chr19_57750240_+SINEAluName=AluSq2
ADediting_785840chr19_57750242_+SINEAluName=AluSq2
ADediting_785841chr19_57750246_+SINEAluName=AluSq2
ADediting_785842chr19_57750247_+SINEAluName=AluSq2
ADediting_785843chr19_57750248_+SINEAluName=AluSq2
ADediting_785844chr19_57750287_+SINEAluName=AluSq2
ADediting_785845chr19_57750312_+SINEAluName=AluSq2
ADediting_785846chr19_57750333_+SINEAluName=AluSq2
ADediting_785847chr19_57750334_+SINEAluName=AluSq2
ADediting_785848chr19_57750339_+SINEAluName=AluSq2
ADediting_785849chr19_57750344_+SINEAluName=AluSq2
ADediting_785850chr19_57750357_+SINEAluName=AluSq2
ADediting_785851chr19_57750360_+SINEAluName=AluSq2
ADediting_785852chr19_57750364_+SINEAluName=AluSq2
ADediting_785853chr19_57750373_+SINEAluName=AluSq2
ADediting_785854chr19_57750387_+SINEAluName=AluSq2
ADediting_785855chr19_57750411_+SINEAluName=AluSq2
ADediting_785856chr19_57750422_+SINEAluName=AluSq2
ADediting_785857chr19_57750445_+SINEAluName=AluSq2
ADediting_785858chr19_57756906_+SINEAluName=AluJo
ADediting_785859chr19_57756938_+SINEAluName=AluJo
ADediting_785860chr19_57756953_+SINEAluName=AluJo
ADediting_785861chr19_57756987_+SINEAluName=AluJo
ADediting_785862chr19_57757017_+SINEAluName=AluJo
ADediting_785863chr19_57757019_+SINEAluName=AluJo
ADediting_785864chr19_57757021_+SINEAluName=AluJo
ADediting_785865chr19_57757047_+SINEAluName=AluJo
ADediting_785866chr19_57757058_+SINEAluName=AluJo
ADediting_785867chr19_57757071_+SINEAluName=AluJo
ADediting_785868chr19_57757075_+SINEAluName=AluJo
ADediting_785869chr19_57757104_+SINEAluName=AluJo
ADediting_785870chr19_57757110_+SINEAluName=AluJo
ADediting_785871chr19_57757722_+SINEAluName=AluJr
ADediting_785872chr19_57757731_+SINEAluName=AluJr
ADediting_785873chr19_57757750_+SINEAluName=AluJr
ADediting_1559375chr19_57756870_+SINEAluName=AluJo

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RNA A-to-I editing events in the alternative splicing sites for ZNF776

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZNF776

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for ZNF776

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for ZNF776

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1559375chr19_57756870_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-2355-5pchr1957756868577568747mer-1a5775685557756874144-14.28
ADediting_1559375chr19_57756870_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-3613-3pchr1957756863577568697mer-m85775684757756870153-4.8
ADediting_785858chr19_57756906_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-148a-3pchr1957756904577569107mer-m85775689057756911154-19.06
ADediting_785858chr19_57756906_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-148b-3pchr1957756904577569107mer-m85775689057756911154-21.18
ADediting_785858chr19_57756906_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-152-3pchr1957756904577569107mer-m85775689157756911154-23.6
ADediting_785858chr19_57756906_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-148a-3pchr1957756904577569107mer-m85775689057756911154-19.06
ADediting_785858chr19_57756906_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-148b-3pchr1957756904577569107mer-m85775689057756911154-21.18
ADediting_785858chr19_57756906_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-152-3pchr1957756904577569107mer-m85775689157756911154-23.6
ADediting_785860chr19_57756953_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-1199-5pchr1957756946577569527mer-m85775693457756953156-28.57
ADediting_785860chr19_57756953_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-3622a-3pchr1957756949577569568mer-1a5775693557756956148-19.86
ADediting_785860chr19_57756953_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-3622b-3pchr1957756949577569568mer-1a5775693657756956157-24.67
ADediting_785860chr19_57756953_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-6751-3pchr1957756946577569527mer-m85775693357756953141-13.15
ADediting_785860chr19_57756953_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-1199-5pchr1957756946577569527mer-m85775693457756953156-28.57
ADediting_785860chr19_57756953_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-3622a-3pchr1957756949577569568mer-1a5775693557756956148-19.86
ADediting_785860chr19_57756953_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-3622b-3pchr1957756949577569568mer-1a5775693657756956157-24.67
ADediting_785860chr19_57756953_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-6751-3pchr1957756946577569527mer-m85775693357756953141-13.15
ADediting_785861chr19_57756987_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-4726-3pchr1957756981577569888mer-1a5775696957756988146-22.36
ADediting_785861chr19_57756987_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-4726-3pchr1957756981577569888mer-1a5775696957756988146-22.36
ADediting_785862chr19_57757017_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-1283chr1957757013577570208mer-1a5775699957757020147-12.11
ADediting_785862chr19_57757017_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-3613-3pchr1957757010577570167mer-m85775699457757017140-7.05
ADediting_785862chr19_57757017_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-519a-2-5pchr1957757015577570228mer-1a5775700257757022153-16.75
ADediting_785862chr19_57757017_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-520b-5pchr1957757015577570228mer-1a5775700257757022153-16.75
ADediting_785862chr19_57757017_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-1283chr1957757013577570208mer-1a5775699957757020147-12.11
ADediting_785862chr19_57757017_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-3613-3pchr1957757010577570167mer-m85775699457757017140-7.05
ADediting_785862chr19_57757017_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-519a-2-5pchr1957757015577570228mer-1a5775700257757022153-16.75
ADediting_785862chr19_57757017_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-520b-5pchr1957757015577570228mer-1a5775700257757022153-16.75
ADediting_785864chr19_57757021_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-6883-3pchr1957757016577570227mer-m85775700257757023140-9.74
ADediting_785864chr19_57757021_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-6883-3pchr1957757016577570227mer-m85775700257757023140-9.74
ADediting_785865chr19_57757047_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-3157-5pchr1957757044577570507mer-m85775703057757051164-22.11
ADediting_785865chr19_57757047_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-3157-5pchr1957757044577570507mer-m85775703057757051164-22.11
ADediting_785866chr19_57757058_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-28-5pchr1957757056577570627mer-m85775703857757063149-18.12
ADediting_785866chr19_57757058_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-3139chr1957757056577570627mer-m85775704157757063157-18.17
ADediting_785866chr19_57757058_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-3160-3pchr1957757054577570607mer-m85775703957757061149-17
ADediting_785866chr19_57757058_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-708-5pchr1957757056577570627mer-m85775704257757063152-19.26
ADediting_785866chr19_57757058_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-28-5pchr1957757056577570627mer-m85775703857757063149-18.12
ADediting_785866chr19_57757058_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-3139chr1957757056577570627mer-m85775704157757063157-18.17
ADediting_785866chr19_57757058_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-3160-3pchr1957757054577570607mer-m85775703957757061149-17
ADediting_785866chr19_57757058_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-708-5pchr1957757056577570627mer-m85775704257757063152-19.26
ADediting_785867chr19_57757071_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-4649-3pchr1957757064577570707mer-m85775705157757071147-18.42
ADediting_785867chr19_57757071_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-544bchr1957757065577570717mer-m85775705157757072149-18.39
ADediting_785867chr19_57757071_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-4649-3pchr1957757064577570707mer-m85775705157757071147-18.42
ADediting_785867chr19_57757071_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-544bchr1957757065577570717mer-m85775705157757072149-18.39
ADediting_785868chr19_57757075_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-4759chr1957757072577570787mer-m85775705657757079145-14.1
ADediting_785868chr19_57757075_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-4759chr1957757072577570787mer-m85775705657757079145-14.1
ADediting_785869chr19_57757104_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-1825chr1957757098577571047mer-m85775708857757105144-14.94
ADediting_785869chr19_57757104_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-1825chr1957757098577571047mer-m85775708857757105144-14.94
ADediting_785871chr19_57757722_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-3685chr1957757718577577247mer-m85775770457757725149-18.46
ADediting_785872chr19_57757731_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-5588-3pchr1957757728577577358mer-1a5775771757757735140-13.86
ADediting_785873chr19_57757750_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-7153-3pchr1957757745577577528mer-1a5775773257757752142-14.51

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_785858chr19_57756906_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-10395-3pchr1957756901577569077mer-m85775689157756908151-14.33
ADediting_785858chr19_57756906_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-10395-3pchr1957756901577569077mer-m85775689157756908151-14.33
ADediting_785861chr19_57756987_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-216a-5pchr1957756984577569918mer-1a5775697057756991148-14.11
ADediting_785861chr19_57756987_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-216a-5pchr1957756984577569918mer-1a5775697057756991148-14.11
ADediting_785863chr19_57757019_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-3675-3pchr1957757017577570248mer-1a5775700257757024152-8.78
ADediting_785863chr19_57757019_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-3675-3pchr1957757017577570248mer-1a5775700257757024152-8.78
ADediting_785864chr19_57757021_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-3675-3pchr1957757017577570248mer-1a5775700257757024152-8.78
ADediting_785864chr19_57757021_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-3675-3pchr1957757017577570248mer-1a5775700257757024152-8.78
ADediting_785866chr19_57757058_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-219a-1-3pchr1957757054577570607mer-m85775704057757061144-13.7
ADediting_785866chr19_57757058_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-219a-1-3pchr1957757054577570607mer-m85775704057757061144-13.7
ADediting_785867chr19_57757071_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-1304-5pchr1957757064577570707mer-m85775705357757071155-20.39
ADediting_785867chr19_57757071_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-1304-5pchr1957757064577570707mer-m85775705357757071155-20.39
ADediting_785868chr19_57757075_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-3159chr1957757072577570787mer-m85775705757757079149-19.61
ADediting_785868chr19_57757075_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-3159chr1957757072577570787mer-m85775705757757079149-19.61
ADediting_785869chr19_57757104_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-4473chr1957757097577571037mer-m85775708357757104147-15.39
ADediting_785869chr19_57757104_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-6080chr1957757098577571047mer-m85775708157757105141-22.42
ADediting_785869chr19_57757104_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-7975chr1957757100577571067mer-m85775709057757107140-11.35
ADediting_785869chr19_57757104_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-4473chr1957757097577571037mer-m85775708357757104147-15.39
ADediting_785869chr19_57757104_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-6080chr1957757098577571047mer-m85775708157757105141-22.42
ADediting_785869chr19_57757104_+ENSG00000152443.13ENST00000451849.1ZNF776-203hsa-miR-7975chr1957757100577571067mer-m85775709057757107140-11.35
ADediting_785872chr19_57757731_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-371a-5pchr1957757725577577328mer-1a5775771357757732145-11.6
ADediting_785872chr19_57757731_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-4474-5pchr1957757729577577357mer-m85775771657757736145-14.69

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_785831chr19_57749181_+ENSG00000152443.13ENST00000473585.1ZNF776-204hsa-miR-3940-3pchr1957749179577491857mer-m85774916557749186140-22.76
ADediting_785832chr19_57749232_+ENSG00000152443.13ENST00000473585.1ZNF776-204hsa-miR-3189-3pchr1957749227577492337mer-m85774921157749234153-26.36
ADediting_785832chr19_57749232_+ENSG00000152443.13ENST00000473585.1ZNF776-204hsa-miR-6813-3pchr1957749228577492347mer-m85774921557749235140-11.59
ADediting_785833chr19_57749238_+ENSG00000152443.13ENST00000473585.1ZNF776-204hsa-miR-383-3pchr1957749232577492387mer-m85774922157749239140-14.49
ADediting_785833chr19_57749238_+ENSG00000152443.13ENST00000473585.1ZNF776-204hsa-miR-7977chr1957749235577492417mer-m85774922557749242140-13.07
ADediting_785858chr19_57756906_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-148a-3pchr1957756905577569117mer-m85775689157756912154-19.06
ADediting_785858chr19_57756906_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-148b-3pchr1957756905577569117mer-m85775689157756912154-21.18
ADediting_785858chr19_57756906_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-152-3pchr1957756905577569117mer-m85775689257756912154-23.6
ADediting_785860chr19_57756953_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-1199-5pchr1957756947577569537mer-m85775693557756954156-28.57
ADediting_785860chr19_57756953_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-3622a-3pchr1957756950577569578mer-1a5775693657756957148-19.86
ADediting_785860chr19_57756953_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-3622b-3pchr1957756950577569578mer-1a5775693757756957157-24.67
ADediting_785860chr19_57756953_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-6751-3pchr1957756947577569537mer-m85775693457756954141-13.15
ADediting_785861chr19_57756987_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-4726-3pchr1957756982577569898mer-1a5775697057756989146-22.36
ADediting_785862chr19_57757017_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-1283chr1957757014577570218mer-1a5775700057757021147-12.11
ADediting_785862chr19_57757017_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-3613-3pchr1957757011577570177mer-m85775699557757018140-7.05
ADediting_785862chr19_57757017_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-519a-2-5pchr1957757016577570238mer-1a5775700357757023153-16.75
ADediting_785862chr19_57757017_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-520b-5pchr1957757016577570238mer-1a5775700357757023153-16.75
ADediting_785864chr19_57757021_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-6883-3pchr1957757017577570237mer-m85775700357757024140-9.74
ADediting_785865chr19_57757047_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-3157-5pchr1957757045577570517mer-m85775703157757052164-22.11
ADediting_785866chr19_57757058_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-28-5pchr1957757057577570637mer-m85775703957757064149-18.12
ADediting_785866chr19_57757058_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-3139chr1957757057577570637mer-m85775704257757064157-18.17
ADediting_785866chr19_57757058_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-3160-3pchr1957757055577570617mer-m85775704057757062149-17
ADediting_785866chr19_57757058_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-708-5pchr1957757057577570637mer-m85775704357757064152-19.26
ADediting_785867chr19_57757071_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-4649-3pchr1957757065577570717mer-m85775705257757072147-18.42
ADediting_785867chr19_57757071_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-544bchr1957757066577570727mer-m85775705257757073149-18.39
ADediting_785868chr19_57757075_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-4759chr1957757073577570797mer-m85775705757757080145-14.1
ADediting_785869chr19_57757104_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-1825chr1957757099577571057mer-m85775708957757106144-14.94

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_785831chr19_57749181_+ENSG00000152443.13ENST00000473585.1ZNF776-204hsa-miR-3190-5pchr1957749176577491827mer-m85774916557749183144-16.24
ADediting_785831chr19_57749181_+ENSG00000152443.13ENST00000473585.1ZNF776-204hsa-miR-548schr1957749175577491817mer-m85774915857749182151-13.28
ADediting_785858chr19_57756906_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-10395-3pchr1957756902577569087mer-m85775689257756909151-14.33
ADediting_785861chr19_57756987_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-216a-5pchr1957756985577569928mer-1a5775697157756992148-14.11
ADediting_785863chr19_57757019_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-3675-3pchr1957757018577570258mer-1a5775700357757025152-8.78
ADediting_785864chr19_57757021_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-3675-3pchr1957757018577570258mer-1a5775700357757025152-8.78
ADediting_785866chr19_57757058_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-219a-1-3pchr1957757055577570617mer-m85775704157757062144-13.7
ADediting_785867chr19_57757071_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-1304-5pchr1957757065577570717mer-m85775705457757072155-20.39
ADediting_785868chr19_57757075_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-3159chr1957757073577570797mer-m85775705857757080149-19.61
ADediting_785869chr19_57757104_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-4473chr1957757098577571047mer-m85775708457757105147-15.39
ADediting_785869chr19_57757104_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-6080chr1957757099577571057mer-m85775708257757106141-22.42
ADediting_785869chr19_57757104_+ENSG00000152443.13ENST00000489376.1ZNF776-205hsa-miR-7975chr1957757101577571077mer-m85775709157757108140-11.35

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1631458chr19_40282624_-ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-641chr1957755727577557337mer-m85775571257755734154-19.47
ADediting_291761chr11_93733708_-ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-1304-3pchr1957755191577551977mer-m85775517957755198143-18.66
ADediting_843620chr2_207754818_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-4775chr1957754777577547837mer-m85775476257754784146-8.38
ADediting_843620chr2_207754818_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-4775chr1957755390577553967mer-m85775537657755397140-6.35
ADediting_843620chr2_207754818_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-4775chr1957756065577560717mer-m85775605157756072151-9.36
ADediting_843620chr2_207754818_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-4775chr1957757570577575767mer-m85775755657757577149-8.36
ADediting_98289chr1_32086992_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-5585-3pchr1957755858577558647mer-m85775584657755865155-20.91

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1097295chr3_85385762_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-5688chr1957756464577564707mer-m85775645057756471140-10.81
ADediting_1337757chr7_5495852_-ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-589-3pchr1957756311577563177mer-m85775629657756318146-16.35
ADediting_843620chr2_207754818_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-4775chr1957755029577550357mer-m85775500957755036150-11.4
ADediting_98288chr1_32086990_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-5585-3pchr1957755058577550647mer-m85775504457755065140-9.95
ADediting_98289chr1_32086992_+ENSG00000152443.13ENST00000317178.10ZNF776-201hsa-miR-5585-3pchr1957755058577550647mer-m85775504457755065140-9.95

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ZNF776

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000473585.1lncRNASoverviewSoverview
ENST00000317178.10protein_codingSoverviewSoverview
ENST00000489376.1lncRNASoverviewSoverview
ENST00000451849.1protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_1559375ENST00000317178.10chr19_57756870_+3984-1508.30-1508.70-1532.00
ADediting_785858ENST00000317178.10chr19_57756906_+4020-1511.50-1508.70-1532.00
ADediting_785859ENST00000317178.10chr19_57756938_+4052-1508.60-1508.70-1532.00
ADediting_785860ENST00000317178.10chr19_57756953_+4067-1510.70-1508.70-1532.00
ADediting_785861ENST00000317178.10chr19_57756987_+4101-1515.30-1508.70-1532.00
ADediting_785862ENST00000317178.10chr19_57757017_+4131-1508.80-1508.70-1532.00
ADediting_785863ENST00000317178.10chr19_57757019_+4133-1508.40-1508.70-1532.00
ADediting_785864ENST00000317178.10chr19_57757021_+4135-1507.80-1508.70-1532.00
ADediting_785865ENST00000317178.10chr19_57757047_+4161-1515.90-1508.70-1532.00
ADediting_785866ENST00000317178.10chr19_57757058_+4172-1508.70-1508.70-1532.00
ADediting_785867ENST00000317178.10chr19_57757071_+4185-1508.40-1508.70-1532.00
ADediting_785868ENST00000317178.10chr19_57757075_+4189-1508.70-1508.70-1532.00
ADediting_785869ENST00000317178.10chr19_57757104_+4218-1513.60-1508.70-1532.00
ADediting_785870ENST00000317178.10chr19_57757110_+4224-1508.80-1508.70-1532.00
ADediting_785871ENST00000317178.10chr19_57757722_+4836-1510.90-1508.70-1532.00
ADediting_785872ENST00000317178.10chr19_57757731_+4845-1508.90-1508.70-1532.00
ADediting_785873ENST00000317178.10chr19_57757750_+4864-1508.40-1508.70-1532.00
ADediting_785858ENST00000451849.1chr19_57756906_+143-143.30-140.90-163.40
ADediting_785859ENST00000451849.1chr19_57756938_+175-142.00-140.90-163.40
ADediting_785860ENST00000451849.1chr19_57756953_+190-146.20-140.90-163.40
ADediting_785861ENST00000451849.1chr19_57756987_+224-146.80-140.90-163.40
ADediting_785862ENST00000451849.1chr19_57757017_+254-141.60-140.90-163.40
ADediting_785863ENST00000451849.1chr19_57757019_+256-142.80-140.90-163.40
ADediting_785864ENST00000451849.1chr19_57757021_+258-144.80-140.90-163.40
ADediting_785865ENST00000451849.1chr19_57757047_+284-146.60-140.90-163.40
ADediting_785866ENST00000451849.1chr19_57757058_+295-142.90-140.90-163.40
ADediting_785867ENST00000451849.1chr19_57757071_+308-144.00-140.90-163.40
ADediting_785868ENST00000451849.1chr19_57757075_+312-140.90-140.90-163.40
ADediting_785869ENST00000451849.1chr19_57757104_+341-140.90-140.90-163.40
ADediting_785870ENST00000451849.1chr19_57757110_+347-140.90-140.90-163.40

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_785831ENST00000473585.1chr19_57749181_+295-173.90-167.70-176.80
ADediting_785832ENST00000473585.1chr19_57749232_+346-168.20-167.70-176.80
ADediting_785833ENST00000473585.1chr19_57749238_+352-170.30-167.70-176.80
ADediting_785858ENST00000489376.1chr19_57756906_+1683-527.00-524.20-542.80
ADediting_785859ENST00000489376.1chr19_57756938_+1715-524.60-524.20-542.80
ADediting_785860ENST00000489376.1chr19_57756953_+1730-527.20-524.20-542.80
ADediting_785861ENST00000489376.1chr19_57756987_+1764-530.80-524.20-542.80
ADediting_785862ENST00000489376.1chr19_57757017_+1794-525.70-524.20-542.80
ADediting_785863ENST00000489376.1chr19_57757019_+1796-524.00-524.20-542.80
ADediting_785864ENST00000489376.1chr19_57757021_+1798-526.80-524.20-542.80
ADediting_785865ENST00000489376.1chr19_57757047_+1824-529.30-524.20-542.80
ADediting_785866ENST00000489376.1chr19_57757058_+1835-525.10-524.20-542.80
ADediting_785867ENST00000489376.1chr19_57757071_+1848-525.30-524.20-542.80
ADediting_785868ENST00000489376.1chr19_57757075_+1852-524.20-524.20-542.80
ADediting_785869ENST00000489376.1chr19_57757104_+1881-524.20-524.20-542.80
ADediting_785870ENST00000489376.1chr19_57757110_+1887-524.20-524.20-542.80

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Relation with ADAR for ZNF776

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_785862chr19_57757017_+4.86107247722269e-130.3953369625260945.63406579845062e-140.4096709254878550.7997726771374040.0144635341051499
DLPFCADediting_785863chr19_57757019_+2.3858366882237e-140.415200111551031.06570636708085e-140.4202950156938090.06685723248873490.104223934055575
CERADediting_785866chr19_57757058_+7.04414114707207e-060.3575878309102874.01032893127458e-050.3287090048359210.1035659627330940.133431032009538
TCXADediting_785866chr19_57757058_+0.001549043940426020.2562624918146111.17783241974766e-100.4952067417995640.000161536191631278-0.303283603791699
DLPFCADediting_785869chr19_57757104_+1.4441467393976e-060.2696917981139091.47355239485092e-100.3535610347291320.611711883145248-0.0289424042320904

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.06119432189303e-850.8449459755978552.3399350425286e-600.7631579498946252.61890388679436e-100.349001923204745
AC4.23156902756343e-670.8377115499838591.50123016752188e-450.7452646615452892.51701769111916e-150.472764665732189
PCC2.17682187127315e-490.8280942744261458.84813058675379e-480.8204913756350760.0001450304801935120.2715167139529
CER1.88427688712016e-430.8520708988198098.00077206464834e-380.8208230156274130.009993814288390710.209742687709061
TCX1.35554798731058e-260.7334811646729688.21847426176076e-170.6124460953779210.01026077322577380.209015983770935
FP2.29017580853231e-370.7779946946436829.15429115349322e-360.7671020561677260.0001199184742338970.284322167034284
IFG5.75235730747878e-080.8537536460089821.14621077507499e-070.8440389757478840.007677119904821520.520251565123219
PG1.66956310222168e-590.873773639365322.5606615569879e-410.7921725803780180.8521258985039910.0137601108200922
STG3.95195298868129e-230.8365009622998534.50779330709807e-150.7276365135132950.1037839254787250.178741890531523

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Relation with AD stages for ZNF776

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
IFGADediting_785863chr19_57757019_+0.0449220351546537-0.404459265579513

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER2.19326917399343e-060.437511594907992
TCX0.0009869908889141280.315489971324518

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RelatedDrugs for ZNF776

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ZNF776

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource