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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for ENDOV

check button Gene summary
Gene informationGene symbol

ENDOV

Gene ID

284131

Gene nameendonuclease V
Synonyms-
Cytomap

17q25.3

Type of geneprotein-coding
Descriptionendonuclease VhEndoVinosine-specific endoribonuclease
Modification date20200313
UniProtAcc

Q8N8Q3,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for ENDOV

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_671935(80415974, +), ADediting_671936(80415982, +), ADediting_671937(80415983, +), ADediting_671938(80415988, +), ADediting_671939(80415991, +), ADediting_671940(80415999, +), ADediting_671941(80416015, +), ADediting_671942(80416018, +), ADediting_671943(80416023, +), ADediting_671944(80416042, +), ADediting_671945(80416048, +), ADediting_671946(80416052, +), ADediting_671947(80416054, +), ADediting_671948(80416061, +), ADediting_671949(80416062, +), ADediting_671950(80416073, +), ADediting_671951(80416076, +), ADediting_671952(80416078, +), ADediting_671953(80416080, +), ADediting_671954(80416082, +), ADediting_671955(80416085, +), ADediting_671956(80416086, +), ADediting_671957(80416087, +), ADediting_671958(80416090, +), ADediting_671959(80416110, +), ADediting_671960(80416116, +), ADediting_671961(80416117, +), ADediting_671962(80416122, +), ADediting_671963(80416126, +), ADediting_671964(80416133, +), ADediting_671965(80416146, +), ADediting_671966(80416149, +), ADediting_671967(80416158, +), ADediting_671968(80416192, +), ADediting_671969(80416799, +), ADediting_671970(80416800, +), ADediting_671971(80416805, +), ADediting_671972(80416811, +), ADediting_671973(80416813, +), ADediting_671974(80416843, +), ADediting_671975(80416844, +), ADediting_671976(80416857, +), ADediting_671977(80416858, +), ADediting_671978(80416870, +), ADediting_671979(80416884, +), ADediting_671980(80416888, +), ADediting_671981(80416894, +), ADediting_671982(80416903, +), ADediting_671983(80416929, +), ADediting_671984(80416938, +), ADediting_671985(80416940, +), ADediting_671986(80416944, +), ADediting_671987(80416952, +), ADediting_671988(80416964, +), ADediting_671989(80416976, +), ADediting_671990(80416989, +), ADediting_671991(80416990, +), ADediting_671992(80417016, +), ADediting_671993(80417017, +), ADediting_671994(80417024, +), ADediting_671995(80417029, +), ADediting_671996(80417039, +), ADediting_671997(80417047, +), ADediting_671998(80418900, +), ADediting_671999(80418916, +), ADediting_672000(80418917, +), ADediting_672001(80418922, +), ADediting_672002(80418960, +), ADediting_672003(80418984, +), ADediting_672004(80418993, +), ADediting_672005(80418994, +), ADediting_672006(80419034, +), ADediting_672007(80419052, +), ADediting_672008(80419058, +), ADediting_672009(80419062, +), ADediting_672010(80420074, +), ADediting_672011(80420757, +), ADediting_672012(80420777, +), ADediting_672013(80420778, +), ADediting_672014(80420781, +), ADediting_672015(80420795, +), ADediting_672016(80420804, +), ADediting_672017(80420807, +), ADediting_672018(80420817, +), ADediting_672019(80420830, +), ADediting_672020(80420857, +), ADediting_672021(80420861, +), ADediting_672022(80420877, +), ADediting_672023(80420886, +), ADediting_672024(80420938, +), ADediting_672025(80420950, +), ADediting_672026(80422906, +), ADediting_672027(80434682, +), ADediting_672028(80434707, +), ADediting_672029(80434717, +), ADediting_672030(80434764, +), ADediting_672031(80434825, +), ADediting_672032(80435756, +), ADediting_672033(80435823, +), ADediting_672034(80435890, +), ADediting_672035(80435892, +), ADediting_672036(80435989, +), ADediting_672037(80435990, +), ADediting_1549788(80416881, +), ADediting_1549789(80434690, +), ADediting_1549790(80434691, +), ADediting_1549791(80434696, +), ADediting_1549792(80434759, +), ADediting_1549793(80434760, +), ADediting_1549794(80434800, +), ADediting_1549795(80434803, +), ADediting_1549796(80434823, +), ADediting_1549797(80434826, +), ADediting_1549798(80434861, +), ADediting_1549799(80434865, +), ADediting_1549800(80435878, +), ADediting_1549801(80435939, +), ADediting_1549802(80435976, +), ADediting_1549803(80435977, +), ADediting_1549804(80436029, +),

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RNA editing positional annotations for ENDOV using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_671935chr17_80415974_+intronic
ADediting_671936chr17_80415982_+intronic
ADediting_671937chr17_80415983_+intronic
ADediting_671938chr17_80415988_+intronic
ADediting_671939chr17_80415991_+intronic
ADediting_671940chr17_80415999_+intronic
ADediting_671941chr17_80416015_+intronic
ADediting_671942chr17_80416018_+intronic
ADediting_671943chr17_80416023_+intronic
ADediting_671944chr17_80416042_+intronic
ADediting_671945chr17_80416048_+intronic
ADediting_671946chr17_80416052_+intronic
ADediting_671947chr17_80416054_+intronic
ADediting_671948chr17_80416061_+intronic
ADediting_671949chr17_80416062_+intronic
ADediting_671950chr17_80416073_+intronic
ADediting_671951chr17_80416076_+intronic
ADediting_671952chr17_80416078_+intronic
ADediting_671953chr17_80416080_+intronic
ADediting_671954chr17_80416082_+intronic
ADediting_671955chr17_80416085_+intronic
ADediting_671956chr17_80416086_+intronic
ADediting_671957chr17_80416087_+intronic
ADediting_671958chr17_80416090_+intronic
ADediting_671959chr17_80416110_+intronic
ADediting_671960chr17_80416116_+intronic
ADediting_671961chr17_80416117_+intronic
ADediting_671962chr17_80416122_+intronic
ADediting_671963chr17_80416126_+intronic
ADediting_671964chr17_80416133_+intronic
ADediting_671965chr17_80416146_+intronic
ADediting_671966chr17_80416149_+intronic
ADediting_671967chr17_80416158_+intronic
ADediting_671968chr17_80416192_+intronic
ADediting_671969chr17_80416799_+intronic
ADediting_671970chr17_80416800_+intronic
ADediting_671971chr17_80416805_+intronic
ADediting_671972chr17_80416811_+intronic
ADediting_671973chr17_80416813_+intronic
ADediting_671974chr17_80416843_+intronic
ADediting_671975chr17_80416844_+intronic
ADediting_671976chr17_80416857_+intronic
ADediting_671977chr17_80416858_+intronic
ADediting_671978chr17_80416870_+intronic
ADediting_671979chr17_80416884_+intronic
ADediting_671980chr17_80416888_+intronic
ADediting_671981chr17_80416894_+intronic
ADediting_671982chr17_80416903_+intronic
ADediting_671983chr17_80416929_+intronic
ADediting_671984chr17_80416938_+intronic
ADediting_671985chr17_80416940_+intronic
ADediting_671986chr17_80416944_+intronic
ADediting_671987chr17_80416952_+intronic
ADediting_671988chr17_80416964_+intronic
ADediting_671989chr17_80416976_+intronic
ADediting_671990chr17_80416989_+intronic
ADediting_671991chr17_80416990_+intronic
ADediting_671992chr17_80417016_+intronic
ADediting_671993chr17_80417017_+intronic
ADediting_671994chr17_80417024_+intronic
ADediting_671995chr17_80417029_+intronic
ADediting_671996chr17_80417039_+intronic
ADediting_671997chr17_80417047_+intronic
ADediting_671998chr17_80418900_+intronic
ADediting_671999chr17_80418916_+intronic
ADediting_672000chr17_80418917_+intronic
ADediting_672001chr17_80418922_+intronic
ADediting_672002chr17_80418960_+intronic
ADediting_672003chr17_80418984_+intronic
ADediting_672004chr17_80418993_+intronic
ADediting_672005chr17_80418994_+intronic
ADediting_672006chr17_80419034_+intronic
ADediting_672007chr17_80419052_+intronic
ADediting_672008chr17_80419058_+intronic
ADediting_672009chr17_80419062_+intronic
ADediting_672010chr17_80420074_+UTR3
ADediting_672011chr17_80420757_+intronic
ADediting_672012chr17_80420777_+intronic
ADediting_672013chr17_80420778_+intronic
ADediting_672014chr17_80420781_+intronic
ADediting_672015chr17_80420795_+intronic
ADediting_672016chr17_80420804_+intronic
ADediting_672017chr17_80420807_+intronic
ADediting_672018chr17_80420817_+intronic
ADediting_672019chr17_80420830_+intronic
ADediting_672020chr17_80420857_+intronic
ADediting_672021chr17_80420861_+intronic
ADediting_672022chr17_80420877_+intronic
ADediting_672023chr17_80420886_+intronic
ADediting_672024chr17_80420938_+intronic
ADediting_672025chr17_80420950_+intronic
ADediting_672026chr17_80422906_+intronic
ADediting_672027chr17_80434682_+intronic
ADediting_672028chr17_80434707_+intronic
ADediting_672029chr17_80434717_+intronic
ADediting_672030chr17_80434764_+intronic
ADediting_672031chr17_80434825_+intronic
ADediting_672032chr17_80435756_+intronic
ADediting_672033chr17_80435823_+intronic
ADediting_672034chr17_80435890_+intronic
ADediting_672035chr17_80435892_+intronic
ADediting_672036chr17_80435989_+intronic
ADediting_672037chr17_80435990_+intronic
ADediting_1549788chr17_80416881_+intronic
ADediting_1549789chr17_80434690_+intronic
ADediting_1549790chr17_80434691_+intronic
ADediting_1549791chr17_80434696_+intronic
ADediting_1549792chr17_80434759_+intronic
ADediting_1549793chr17_80434760_+intronic
ADediting_1549794chr17_80434800_+intronic
ADediting_1549795chr17_80434803_+intronic
ADediting_1549796chr17_80434823_+intronic
ADediting_1549797chr17_80434826_+intronic
ADediting_1549798chr17_80434861_+intronic
ADediting_1549799chr17_80434865_+intronic
ADediting_1549800chr17_80435878_+intronic
ADediting_1549801chr17_80435939_+intronic
ADediting_1549802chr17_80435976_+intronic
ADediting_1549803chr17_80435977_+intronic
ADediting_1549804chr17_80436029_+intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_671935chr17_80415974_+SINEAluName=AluSp
ADediting_671936chr17_80415982_+SINEAluName=AluSp
ADediting_671937chr17_80415983_+SINEAluName=AluSp
ADediting_671938chr17_80415988_+SINEAluName=AluSp
ADediting_671939chr17_80415991_+SINEAluName=AluSp
ADediting_671940chr17_80415999_+SINEAluName=AluSp
ADediting_671941chr17_80416015_+SINEAluName=AluSp
ADediting_671942chr17_80416018_+SINEAluName=AluSp
ADediting_671943chr17_80416023_+SINEAluName=AluSp
ADediting_671944chr17_80416042_+SINEAluName=AluSp
ADediting_671945chr17_80416048_+SINEAluName=AluSp
ADediting_671946chr17_80416052_+SINEAluName=AluSp
ADediting_671947chr17_80416054_+SINEAluName=AluSp
ADediting_671948chr17_80416061_+SINEAluName=AluSp
ADediting_671949chr17_80416062_+SINEAluName=AluSp
ADediting_671950chr17_80416073_+SINEAluName=AluSp
ADediting_671951chr17_80416076_+SINEAluName=AluSp
ADediting_671952chr17_80416078_+SINEAluName=AluSp
ADediting_671953chr17_80416080_+SINEAluName=AluSp
ADediting_671954chr17_80416082_+SINEAluName=AluSp
ADediting_671955chr17_80416085_+SINEAluName=AluSp
ADediting_671956chr17_80416086_+SINEAluName=AluSp
ADediting_671957chr17_80416087_+SINEAluName=AluSp
ADediting_671958chr17_80416090_+SINEAluName=AluSp
ADediting_671959chr17_80416110_+SINEAluName=AluSp
ADediting_671960chr17_80416116_+SINEAluName=AluSp
ADediting_671961chr17_80416117_+SINEAluName=AluSp
ADediting_671962chr17_80416122_+SINEAluName=AluSp
ADediting_671963chr17_80416126_+SINEAluName=AluSp
ADediting_671964chr17_80416133_+SINEAluName=AluSp
ADediting_671965chr17_80416146_+SINEAluName=AluSp
ADediting_671966chr17_80416149_+SINEAluName=AluSp
ADediting_671967chr17_80416158_+SINEAluName=AluSp
ADediting_671968chr17_80416192_+SINEAluName=AluSp
ADediting_671969chr17_80416799_+SINEAluName=AluJo
ADediting_671970chr17_80416800_+SINEAluName=AluJo
ADediting_671971chr17_80416805_+SINEAluName=AluJo
ADediting_671972chr17_80416811_+SINEAluName=AluJo
ADediting_671973chr17_80416813_+SINEAluName=AluJo
ADediting_671974chr17_80416843_+SINEAluName=AluJo
ADediting_671975chr17_80416844_+SINEAluName=AluJo
ADediting_671976chr17_80416857_+SINEAluName=AluJo
ADediting_671977chr17_80416858_+SINEAluName=AluJo
ADediting_671978chr17_80416870_+SINEAluName=AluJo
ADediting_671979chr17_80416884_+SINEAluName=AluJo
ADediting_671980chr17_80416888_+SINEAluName=AluJo
ADediting_671981chr17_80416894_+SINEAluName=AluJo
ADediting_671982chr17_80416903_+SINEAluName=AluJo
ADediting_671983chr17_80416929_+SINEAluName=AluJo
ADediting_671984chr17_80416938_+SINEAluName=AluJo
ADediting_671985chr17_80416940_+SINEAluName=AluJo
ADediting_671986chr17_80416944_+SINEAluName=AluJo
ADediting_671987chr17_80416952_+SINEAluName=AluJo
ADediting_671988chr17_80416964_+SINEAluName=AluJo
ADediting_671989chr17_80416976_+SINEAluName=AluJo
ADediting_671990chr17_80416989_+SINEAluName=AluJo
ADediting_671991chr17_80416990_+SINEAluName=AluJo
ADediting_671992chr17_80417016_+SINEAluName=AluJo
ADediting_671993chr17_80417017_+SINEAluName=AluJo
ADediting_671994chr17_80417024_+SINEAluName=AluJo
ADediting_671995chr17_80417029_+SINEAluName=AluJo
ADediting_671996chr17_80417039_+SINEAluName=AluJo
ADediting_671997chr17_80417047_+SINEAluName=AluJo
ADediting_671998chr17_80418900_+SINEAluName=AluY
ADediting_671999chr17_80418916_+SINEAluName=AluY
ADediting_672000chr17_80418917_+SINEAluName=AluY
ADediting_672001chr17_80418922_+SINEAluName=AluY
ADediting_672002chr17_80418960_+SINEAluName=AluY
ADediting_672003chr17_80418984_+SINEAluName=AluY
ADediting_672004chr17_80418993_+SINEAluName=AluY
ADediting_672005chr17_80418994_+SINEAluName=AluY
ADediting_672006chr17_80419034_+SINEAluName=AluY
ADediting_672007chr17_80419052_+SINEAluName=AluY
ADediting_672008chr17_80419058_+SINEAluName=AluY
ADediting_672009chr17_80419062_+SINEAluName=AluY
ADediting_672011chr17_80420757_+SINEAluName=AluSp
ADediting_672012chr17_80420777_+SINEAluName=AluSp
ADediting_672013chr17_80420778_+SINEAluName=AluSp
ADediting_672014chr17_80420781_+SINEAluName=AluSp
ADediting_672015chr17_80420795_+SINEAluName=AluSp
ADediting_672016chr17_80420804_+SINEAluName=AluSp
ADediting_672017chr17_80420807_+SINEAluName=AluSp
ADediting_672018chr17_80420817_+SINEAluName=AluSp
ADediting_672019chr17_80420830_+SINEAluName=AluSp
ADediting_672020chr17_80420857_+SINEAluName=AluSp
ADediting_672021chr17_80420861_+SINEAluName=AluSp
ADediting_672022chr17_80420877_+SINEAluName=AluSp
ADediting_672023chr17_80420886_+SINEAluName=AluSp
ADediting_672024chr17_80420938_+SINEAluName=AluSp
ADediting_672025chr17_80420950_+SINEAluName=AluSp
ADediting_672026chr17_80422906_+SINEAluName=AluY
ADediting_672027chr17_80434682_+SINEAluName=AluJb
ADediting_672028chr17_80434707_+SINEAluName=AluJb
ADediting_672029chr17_80434717_+SINEAluName=AluJb
ADediting_672030chr17_80434764_+SINEAluName=AluJb
ADediting_672031chr17_80434825_+SINEAluName=AluJb
ADediting_672032chr17_80435756_+SINEAluName=AluY
ADediting_672033chr17_80435823_+SINEAluName=AluY
ADediting_672034chr17_80435890_+SINEAluName=AluY
ADediting_672035chr17_80435892_+SINEAluName=AluY
ADediting_672036chr17_80435989_+SINEAluName=AluJb
ADediting_672037chr17_80435990_+SINEAluName=AluJb
ADediting_1549788chr17_80416881_+SINEAluName=AluJo
ADediting_1549789chr17_80434690_+SINEAluName=AluJb
ADediting_1549790chr17_80434691_+SINEAluName=AluJb
ADediting_1549791chr17_80434696_+SINEAluName=AluJb
ADediting_1549792chr17_80434759_+SINEAluName=AluJb
ADediting_1549793chr17_80434760_+SINEAluName=AluJb
ADediting_1549794chr17_80434800_+SINEAluName=AluJb
ADediting_1549795chr17_80434803_+SINEAluName=AluJb
ADediting_1549796chr17_80434823_+SINEAluName=AluJb
ADediting_1549797chr17_80434826_+SINEAluName=AluJb
ADediting_1549798chr17_80434861_+SINEAluName=AluJb
ADediting_1549799chr17_80434865_+SINEAluName=AluJb
ADediting_1549800chr17_80435878_+SINEAluName=AluY
ADediting_1549801chr17_80435939_+SINEAluName=AluJb
ADediting_1549802chr17_80435976_+SINEAluName=AluJb
ADediting_1549803chr17_80435977_+SINEAluName=AluJb
ADediting_1549804chr17_80436029_+SINEAluName=AluJb

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RNA A-to-I editing events in the alternative splicing sites for ENDOV

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ENDOV

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for ENDOV

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for ENDOV

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_672010chr17_80420074_+ENSG00000173818.17ENST00000523999.5ENDOV-229hsa-miR-543chr1780420069804200757mer-m88042005680420076154-14.13

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_671986chr17_80416944_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-340-3pchr1780415821804169457mer-m88041580780416946140-16.55
ADediting_671986chr17_80416944_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-6827-3pchr1780415821804169457mer-m88041580880416946156-20.85
ADediting_671988chr17_80416964_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-5587-3pchr1780416961804169677mer-m88041694880416968163-27.76
ADediting_671989chr17_80416976_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-5091chr1780416970804169767mer-m88041695880416977149-22.47
ADediting_671991chr17_80416990_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-1199-5pchr1780416984804169907mer-m88041697280416991156-29.14
ADediting_671991chr17_80416990_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-125a-5pchr1780416986804169927mer-m88041697080416993147-24.54
ADediting_671991chr17_80416990_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-125b-5pchr1780416986804169927mer-m88041697280416993151-23
ADediting_671991chr17_80416990_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-331-3pchr1780416988804169947mer-1a8041697480416994145-25.52
ADediting_671991chr17_80416990_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-4319chr1780416986804169927mer-m88041697780416993149-21.73
ADediting_671991chr17_80416990_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-6751-3pchr1780416984804169907mer-m88041697180416991141-14.25
ADediting_671992chr17_80417016_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-6777-5pchr1780417010804170178mer-1a8041699380417017154-28.45
ADediting_671993chr17_80417017_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-4667-5pchr1780417011804170177mer-m88041699680417018159-25.42
ADediting_671993chr17_80417017_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-4700-5pchr1780417011804170177mer-m88041700080417018148-21.83
ADediting_671993chr17_80417017_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-6765-3pchr1780417014804170207mer-m88041700180417021148-21.19
ADediting_671993chr17_80417017_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-6804-3pchr1780417015804170217mer-m88041700180417022140-13.3
ADediting_671993chr17_80417017_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-6852-5pchr1780417012804170187mer-m88041699880417019147-23.18
ADediting_671993chr17_80417017_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-7851-3pchr1780417013804170197mer-m88041699880417020167-30.08
ADediting_671993chr17_80417017_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-8089chr1780417011804170177mer-m88041699280417018152-30.77
ADediting_671994chr17_80417024_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-7977chr1780417020804170267mer-m88041701080417027140-13.07
ADediting_671996chr17_80417039_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-10398-5pchr1780417035804170428mer-1a8041702280417042150-22.2
ADediting_671996chr17_80417039_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-532-3pchr1780417033804170397mer-m88041702080417040142-15.91
ADediting_671997chr17_80417047_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-1268achr1780417044804170518mer-1a8041703480417051165-27.52
ADediting_671997chr17_80417047_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-1268bchr1780417044804170518mer-1a8041703280417051165-27.52
ADediting_671997chr17_80417047_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-4486chr1780417046804170527mer-m88041703880417053153-26.36

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_671985chr17_80416940_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-516a-5pchr1780415816804169407mer-m88041579980416941148-22.48
ADediting_671985chr17_80416940_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-6818-3pchr1780415820804169447mer-m88041580780416945151-20.03
ADediting_671986chr17_80416944_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-4421chr1780416940804169478mer-1a8041580880416947149-19.11
ADediting_671986chr17_80416944_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-5699-3pchr1780416940804169478mer-1a8041580880416947151-21.84
ADediting_671986chr17_80416944_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-6818-3pchr1780415820804169447mer-m88041580780416945151-20.03
ADediting_671987chr17_80416952_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-921chr1780416949804169557mer-m88041581480416956142-12.36
ADediting_671988chr17_80416964_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-3620-3pchr1780416963804169697mer-m88041694980416970140-17.03
ADediting_671988chr17_80416964_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-4292chr1780416961804169677mer-m88041695180416968145-20.43
ADediting_671988chr17_80416964_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-5189-5pchr1780416959804169657mer-m88041694080416966146-21.81
ADediting_671988chr17_80416964_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-6791-5pchr1780416961804169677mer-m88041694780416968140-18.58
ADediting_671988chr17_80416964_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-6860chr1780416959804169657mer-m88041694880416966152-24.98
ADediting_671988chr17_80416964_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-939-3pchr1780416960804169667mer-m88041694780416967140-20.43
ADediting_671989chr17_80416976_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-3135bchr1780416972804169787mer-m88041696080416979145-18.63
ADediting_671989chr17_80416976_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-4487chr1780416974804169807mer-m88041696380416981140-16.41
ADediting_671991chr17_80416990_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-188-5pchr1780416989804169957mer-m88041697680416996151-19.51
ADediting_671991chr17_80416990_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-6866-3pchr1780416989804169957mer-m88041697580416996145-19.08
ADediting_671992chr17_80417016_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-12126chr1780417013804170197mer-m88041699580417020153-19.41
ADediting_671992chr17_80417016_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-3150a-3pchr1780417010804170178mer-1a8041699980417017147-24.91
ADediting_671992chr17_80417016_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-3614-5pchr1780417014804170207mer-m88041699780417021144-15.27
ADediting_671992chr17_80417016_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-450a-2-3pchr1780417011804170177mer-m88041699780417018140-12.1
ADediting_671992chr17_80417016_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-6763-5pchr1780417010804170178mer-1a8041700180417017150-22.68
ADediting_671993chr17_80417017_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-12126chr1780417013804170197mer-m88041699580417020153-19.41
ADediting_671993chr17_80417017_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-3614-5pchr1780417014804170207mer-m88041699780417021144-15.27
ADediting_671993chr17_80417017_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-450a-2-3pchr1780417011804170177mer-m88041699780417018140-12.1
ADediting_671994chr17_80417024_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-216a-5pchr1780417022804170298mer-1a8041700880417029150-17.09
ADediting_671996chr17_80417039_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-218-1-3pchr1780417036804170427mer-m88041702280417043140-16.38
ADediting_671997chr17_80417047_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-4455chr1780417044804170518mer-1a8041703680417051153-17.01
ADediting_671997chr17_80417047_+ENSG00000173818.17ENST00000523165.1ENDOV-226hsa-miR-6776-5pchr1780417046804170527mer-m88041703580417053154-21.52

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1391023chr8_140732605_-ENSG00000173818.17ENST00000518644.5ENDOV-205hsa-miR-151a-3pchr1780424311804243177mer-m88042430080424318164-23.43

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1471003chr9_63819626_+ENSG00000173818.17ENST00000517795.5ENDOV-203hsa-miR-4477bchr1780436475804364828mer-1a8043646180436482144-8.97
ADediting_1471003chr9_63819626_+ENSG00000173818.17ENST00000518137.6ENDOV-204hsa-miR-4477bchr1780436475804364828mer-1a8043646180436482144-8.97
ADediting_1471003chr9_63819626_+ENSG00000173818.17ENST00000518901.5ENDOV-206hsa-miR-4477bchr1780436475804364828mer-1a8043646180436482144-8.97
ADediting_1471003chr9_63819626_+ENSG00000173818.17ENST00000518907.5ENDOV-207hsa-miR-4477bchr1780436475804364828mer-1a8043646180436482144-8.97
ADediting_1471003chr9_63819626_+ENSG00000173818.17ENST00000520284.5ENDOV-212hsa-miR-4477bchr1780436475804364828mer-1a8043646180436482144-8.97
ADediting_1471003chr9_63819626_+ENSG00000173818.17ENST00000520367.5ENDOV-213hsa-miR-4477bchr1780436475804364828mer-1a8043646180436482144-8.97
ADediting_1471004chr9_63819627_+ENSG00000173818.17ENST00000517795.5ENDOV-203hsa-miR-4477bchr1780436475804364828mer-1a8043646180436482144-8.97
ADediting_1471004chr9_63819627_+ENSG00000173818.17ENST00000518137.6ENDOV-204hsa-miR-4477bchr1780436475804364828mer-1a8043646180436482144-8.97
ADediting_1471004chr9_63819627_+ENSG00000173818.17ENST00000518901.5ENDOV-206hsa-miR-4477bchr1780436475804364828mer-1a8043646180436482144-8.97
ADediting_1471004chr9_63819627_+ENSG00000173818.17ENST00000518907.5ENDOV-207hsa-miR-4477bchr1780436475804364828mer-1a8043646180436482144-8.97
ADediting_1471004chr9_63819627_+ENSG00000173818.17ENST00000520284.5ENDOV-212hsa-miR-4477bchr1780436475804364828mer-1a8043646180436482144-8.97
ADediting_1471004chr9_63819627_+ENSG00000173818.17ENST00000520367.5ENDOV-213hsa-miR-4477bchr1780436475804364828mer-1a8043646180436482144-8.97
ADediting_1535953chr14_101045971_+ENSG00000173818.17ENST00000517795.5ENDOV-203hsa-miR-381-3pchr1780436661804366677mer-m88043665080436668146-8.96
ADediting_1535953chr14_101045971_+ENSG00000173818.17ENST00000518137.6ENDOV-204hsa-miR-381-3pchr1780436661804366677mer-m88043665080436668146-8.96
ADediting_1535953chr14_101045971_+ENSG00000173818.17ENST00000518901.5ENDOV-206hsa-miR-381-3pchr1780436661804366677mer-m88043665080436668146-8.96
ADediting_1535953chr14_101045971_+ENSG00000173818.17ENST00000518907.5ENDOV-207hsa-miR-381-3pchr1780436661804366677mer-m88043665080436668146-8.96
ADediting_1535953chr14_101045971_+ENSG00000173818.17ENST00000520284.5ENDOV-212hsa-miR-381-3pchr1780436661804366677mer-m88043665080436668146-8.96
ADediting_1535953chr14_101045971_+ENSG00000173818.17ENST00000520367.5ENDOV-213hsa-miR-381-3pchr1780436661804366677mer-m88043665080436668146-8.96
ADediting_1535954chr14_101045974_+ENSG00000173818.17ENST00000517795.5ENDOV-203hsa-miR-381-3pchr1780436661804366677mer-m88043665080436668146-8.96
ADediting_1535954chr14_101045974_+ENSG00000173818.17ENST00000518137.6ENDOV-204hsa-miR-381-3pchr1780436661804366677mer-m88043665080436668146-8.96
ADediting_1535954chr14_101045974_+ENSG00000173818.17ENST00000518901.5ENDOV-206hsa-miR-381-3pchr1780436661804366677mer-m88043665080436668146-8.96
ADediting_1535954chr14_101045974_+ENSG00000173818.17ENST00000518907.5ENDOV-207hsa-miR-381-3pchr1780436661804366677mer-m88043665080436668146-8.96
ADediting_1535954chr14_101045974_+ENSG00000173818.17ENST00000520284.5ENDOV-212hsa-miR-381-3pchr1780436661804366677mer-m88043665080436668146-8.96
ADediting_1535954chr14_101045974_+ENSG00000173818.17ENST00000520367.5ENDOV-213hsa-miR-381-3pchr1780436661804366677mer-m88043665080436668146-8.96

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ENDOV

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000523999.5protein_codingSoverviewSoverview
ENST00000523165.1lncRNASoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_672010ENST00000523999.5chr17_80420074_+405-332.90-331.00-332.90

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_671985ENST00000523165.1chr17_80416940_+170-145.40-142.20-157.90
ADediting_671986ENST00000523165.1chr17_80416944_+174-143.80-142.20-157.90
ADediting_671987ENST00000523165.1chr17_80416952_+182-142.50-142.20-157.90
ADediting_671988ENST00000523165.1chr17_80416964_+194-141.50-142.20-157.90
ADediting_671989ENST00000523165.1chr17_80416976_+206-143.10-142.20-157.90
ADediting_671990ENST00000523165.1chr17_80416989_+219-141.50-142.20-157.90
ADediting_671991ENST00000523165.1chr17_80416990_+220-143.60-142.20-157.90
ADediting_671992ENST00000523165.1chr17_80417016_+246-143.80-142.20-157.90
ADediting_671993ENST00000523165.1chr17_80417017_+247-146.00-142.20-157.90
ADediting_671994ENST00000523165.1chr17_80417024_+254-146.50-142.20-157.90
ADediting_671995ENST00000523165.1chr17_80417029_+259-142.40-142.20-157.90
ADediting_671996ENST00000523165.1chr17_80417039_+269-141.90-142.20-157.90
ADediting_671997ENST00000523165.1chr17_80417047_+277-142.20-142.20-157.90

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Relation with ADAR for ENDOV

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_671935chr17_80415974_+6.48532111144413e-060.3588920176969020.003024922354621660.2405539392885730.1689684690431610.112896241220901
CERADediting_671936chr17_80415982_+2.59807294191985e-060.3729568783726754.92252827206548e-050.3251087131637610.01699278516593970.194647116076346
CERADediting_671937chr17_80415983_+3.25705623164961e-050.3323182237437830.007192972228951330.2186235365668520.02504573428414060.182935728936186
CERADediting_671944chr17_80416042_+4.30548970884376e-060.3652725947840030.003829374832403280.2347759648880610.0128315784700803-0.202758969643841
DLPFCADediting_671949chr17_80416062_+0.1604487614287970.07991235730125640.6527856847452430.02565177751211046.33304148829057e-090.32231388213841
CERADediting_671958chr17_80416090_+6.87475833874203e-060.3579724766605810.004452482036952710.2310098041466250.108609812631203-0.131535183991179
TCXADediting_671958chr17_80416090_+1.02316308954685e-050.3516251561231387.03112133390745e-060.3576170848180530.244674234442438-0.0955716993564378
DLPFCADediting_671959chr17_80416110_+0.0820192534414252-0.09893078725381660.0119132655806418-0.1426705348466941.46798126610229e-100.353590823888937
CERADediting_671960chr17_80416116_+1.631856823944e-060.3798617371785860.002989232671800420.2408412230448620.9522939675999780.00492597668476474
CERADediting_671961chr17_80416117_+1.54665860126054e-050.3448811118976380.001470448357968520.2574450298288170.6356808486328020.0389926970724926
CERADediting_671962chr17_80416122_+1.38974747433998e-060.3822099161398050.0004974594806253120.2809167717569070.962928495450811-0.00382699281443223
CERADediting_671964chr17_80416133_+1.15415249117312e-060.3849034026972620.0001746288473053350.3017911854270360.5214555390002610.0527506899942132
CERADediting_671966chr17_80416149_+1.12255648649721e-050.3501253970284930.0004614318001705170.2824704522010310.57936347888286-0.0456176480814212
CERADediting_671969chr17_80416799_+3.02603376856666e-070.4036391132949780.000776018059076710.271538126857340.888867647527094-0.0115053634471258
CERADediting_671972chr17_80416811_+1.73996071017437e-060.3789187187128513.74691081843114e-050.3298926271928190.6267631409502780.040024135290743
CERADediting_671978chr17_80416870_+3.87126441710383e-050.3293244426250110.001264504495198870.2608414415600250.7342482492018760.0279467887583037
CERADediting_671980chr17_80416888_+2.66093232609215e-060.3725976035135750.01844432063122560.1922236513494310.9266096750096820.00758418682142516
CERADediting_671991chr17_80416990_+9.6791171825534e-060.3525195495041810.0002327232050074230.2962211263637260.283549668077338-0.0881261442238881
DLPFCADediting_671998chr17_80418900_+0.3355982476627280.05486943381656070.286303208957201-0.06074932881666271.04436365582088e-140.420421805515363
DLPFCADediting_671999chr17_80418916_+0.816434073203758-0.01323721280047550.049489581954502-0.1116694872269551.4557382888117e-090.334949268599352
DLPFCADediting_672000chr17_80418917_+0.4129113005103920.04666682417026570.5091936953119-0.03762953711927691.68696945597171e-100.352495288245555
DLPFCADediting_672007chr17_80419052_+0.317425407706457-0.05696670808111640.0088654197830998-0.1484224121274056.22624792948003e-120.37742796882957
CERADediting_672025chr17_80420950_+0.01580087114822330.1967755145378687.17878600353135e-050.3183596849546590.007780509472942250.216533433067888

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC3.50786069837572e-230.5231826122952329.50869843031687e-190.473747345243785.70333338064389e-420.671361600282825
AC4.47742425455994e-880.8932358157313979.15540484154095e-680.8398891327053196.81143942333895e-120.416200005108517
PCC5.10305945249096e-460.8117370084494812.67467440509664e-490.8276811538575870.007650439389223810.192442018405401
CER7.64051756508952e-120.5216633063011932.40365113664955e-060.3741228294946110.9389907764922050.00630199019941141
TCX1.18821145650218e-210.6795033562244052.58910041497892e-160.6045099775082820.139501998923770.12121814379678
FP2.91274656752008e-180.5926616111669464.4454315272719e-160.5599378459602032.54847318483881e-050.309963381108523
IFG1.69193999065963e-070.838245616785461.11649550864785e-050.7584551017924660.1525917863109210.294776216834813
PG2.09619842948118e-110.4657769551517151.2266278354792e-150.5427104397868970.0700596735704570.133133013888534
STG3.08825103727971e-080.5598253869720044.94765750941229e-060.4751485321228130.06736882260727380.200554764304802

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Relation with AD stages for ENDOV

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_672018chr17_80420817_+0.0009463605573419520.31370082774444

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.

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RelatedDrugs for ENDOV

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ENDOV

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource