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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for POLM |
 Gene summary |
| Gene information | Gene symbol | POLM | Gene ID | 27434 |
| Gene name | DNA polymerase mu | |
| Synonyms | Pol Mu|Tdt-N | |
| Cytomap | 7p13 | |
| Type of gene | protein-coding | |
| Description | DNA-directed DNA/RNA polymerase muPol iotapolymerase (DNA) mupolymerase (DNA-directed), muterminal transferase | |
| Modification date | 20200313 | |
| UniProtAcc | Q9NP87, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for POLM |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_1332873(44075124, -), ADediting_1332874(44075153, -), ADediting_1332875(44075162, -), ADediting_1332876(44075179, -), ADediting_1332877(44075188, -), ADediting_1332878(44075189, -), ADediting_1332879(44075199, -), ADediting_1332880(44075215, -), ADediting_1332881(44075269, -), ADediting_1332882(44075772, -), ADediting_1332883(44075787, -), ADediting_1332884(44075847, -), ADediting_1332885(44075848, -), ADediting_1332886(44075850, -), ADediting_1332887(44075867, -), ADediting_1332888(44075877, -), ADediting_1332889(44075892, -), ADediting_1332890(44075903, -), ADediting_1332891(44075921, -), ADediting_1332892(44075957, -), ADediting_1332893(44075958, -), ADediting_1332894(44075966, -), ADediting_1332895(44075971, -), ADediting_1332896(44075990, -), ADediting_1332897(44076018, -), ADediting_1332898(44078201, -), ADediting_1332899(44078218, -), ADediting_1332900(44078219, -), ADediting_1332901(44078244, -), ADediting_1332902(44078245, -), ADediting_1332903(44078252, -), ADediting_1332904(44078260, -), ADediting_1332905(44078270, -), ADediting_1332906(44078297, -), ADediting_1332907(44078298, -), ADediting_1332908(44078326, -), ADediting_1332909(44078338, -), ADediting_1332910(44078342, -), ADediting_1332911(44078344, -), ADediting_1332912(44078347, -), ADediting_1332913(44078354, -), ADediting_1332914(44078366, -), ADediting_1332915(44078371, -), ADediting_1332916(44078382, -), ADediting_1332917(44078383, -), ADediting_1332918(44078384, -), ADediting_1332919(44078409, -), ADediting_1332920(44078430, -), ADediting_1332921(44078460, -), ADediting_1332922(44078464, -), ADediting_1587519(44075072, -), ADediting_1587520(44075089, -), ADediting_1587521(44075123, -), ADediting_1587522(44075147, -), ADediting_1587523(44075277, -), ADediting_1587524(44075750, -), ADediting_1587525(44075854, -), ADediting_1587526(44075885, -), ADediting_1587527(44075932, -), ADediting_1587528(44075989, -), ADediting_1587529(44076003, -), ADediting_1587530(44078259, -), ADediting_1587531(44078440, -), |
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RNA editing positional annotations for POLM using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1332873 | chr7_44075124_- | intronic |
| ADediting_1332874 | chr7_44075153_- | intronic |
| ADediting_1332875 | chr7_44075162_- | intronic |
| ADediting_1332876 | chr7_44075179_- | intronic |
| ADediting_1332877 | chr7_44075188_- | intronic |
| ADediting_1332878 | chr7_44075189_- | intronic |
| ADediting_1332879 | chr7_44075199_- | intronic |
| ADediting_1332880 | chr7_44075215_- | intronic |
| ADediting_1332881 | chr7_44075269_- | intronic |
| ADediting_1332882 | chr7_44075772_- | intronic |
| ADediting_1332883 | chr7_44075787_- | intronic |
| ADediting_1332884 | chr7_44075847_- | intronic |
| ADediting_1332885 | chr7_44075848_- | intronic |
| ADediting_1332886 | chr7_44075850_- | intronic |
| ADediting_1332887 | chr7_44075867_- | intronic |
| ADediting_1332888 | chr7_44075877_- | intronic |
| ADediting_1332889 | chr7_44075892_- | intronic |
| ADediting_1332890 | chr7_44075903_- | intronic |
| ADediting_1332891 | chr7_44075921_- | intronic |
| ADediting_1332892 | chr7_44075957_- | intronic |
| ADediting_1332893 | chr7_44075958_- | intronic |
| ADediting_1332894 | chr7_44075966_- | intronic |
| ADediting_1332895 | chr7_44075971_- | intronic |
| ADediting_1332896 | chr7_44075990_- | intronic |
| ADediting_1332897 | chr7_44076018_- | intronic |
| ADediting_1332898 | chr7_44078201_- | intronic |
| ADediting_1332899 | chr7_44078218_- | intronic |
| ADediting_1332900 | chr7_44078219_- | intronic |
| ADediting_1332901 | chr7_44078244_- | intronic |
| ADediting_1332902 | chr7_44078245_- | intronic |
| ADediting_1332903 | chr7_44078252_- | intronic |
| ADediting_1332904 | chr7_44078260_- | intronic |
| ADediting_1332905 | chr7_44078270_- | intronic |
| ADediting_1332906 | chr7_44078297_- | intronic |
| ADediting_1332907 | chr7_44078298_- | intronic |
| ADediting_1332908 | chr7_44078326_- | UTR3 |
| ADediting_1332909 | chr7_44078338_- | UTR3 |
| ADediting_1332910 | chr7_44078342_- | UTR3 |
| ADediting_1332911 | chr7_44078344_- | UTR3 |
| ADediting_1332912 | chr7_44078347_- | UTR3 |
| ADediting_1332913 | chr7_44078354_- | UTR3 |
| ADediting_1332914 | chr7_44078366_- | UTR3 |
| ADediting_1332915 | chr7_44078371_- | UTR3 |
| ADediting_1332916 | chr7_44078382_- | UTR3 |
| ADediting_1332917 | chr7_44078383_- | UTR3 |
| ADediting_1332918 | chr7_44078384_- | UTR3 |
| ADediting_1332919 | chr7_44078409_- | UTR3 |
| ADediting_1332920 | chr7_44078430_- | UTR3 |
| ADediting_1332921 | chr7_44078460_- | intronic |
| ADediting_1332922 | chr7_44078464_- | intronic |
| ADediting_1587519 | chr7_44075072_- | intronic |
| ADediting_1587520 | chr7_44075089_- | intronic |
| ADediting_1587521 | chr7_44075123_- | intronic |
| ADediting_1587522 | chr7_44075147_- | intronic |
| ADediting_1587523 | chr7_44075277_- | intronic |
| ADediting_1587524 | chr7_44075750_- | intronic |
| ADediting_1587525 | chr7_44075854_- | intronic |
| ADediting_1587526 | chr7_44075885_- | intronic |
| ADediting_1587527 | chr7_44075932_- | intronic |
| ADediting_1587528 | chr7_44075989_- | intronic |
| ADediting_1587529 | chr7_44076003_- | intronic |
| ADediting_1587530 | chr7_44078259_- | intronic |
| ADediting_1587531 | chr7_44078440_- | splicing |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1332873 | chr7_44075124_- | SINE | Alu | Name=AluSq |
| ADediting_1332874 | chr7_44075153_- | SINE | Alu | Name=AluSq |
| ADediting_1332875 | chr7_44075162_- | SINE | Alu | Name=AluSq |
| ADediting_1332876 | chr7_44075179_- | SINE | Alu | Name=AluSq |
| ADediting_1332877 | chr7_44075188_- | SINE | Alu | Name=AluSq |
| ADediting_1332878 | chr7_44075189_- | SINE | Alu | Name=AluSq |
| ADediting_1332879 | chr7_44075199_- | SINE | Alu | Name=AluSq |
| ADediting_1332880 | chr7_44075215_- | SINE | Alu | Name=AluSq |
| ADediting_1332881 | chr7_44075269_- | SINE | Alu | Name=AluSq |
| ADediting_1332882 | chr7_44075772_- | SINE | Alu | Name=AluJb |
| ADediting_1332883 | chr7_44075787_- | SINE | Alu | Name=AluJb |
| ADediting_1332884 | chr7_44075847_- | SINE | Alu | Name=AluJb |
| ADediting_1332885 | chr7_44075848_- | SINE | Alu | Name=AluJb |
| ADediting_1332886 | chr7_44075850_- | SINE | Alu | Name=AluJb |
| ADediting_1332887 | chr7_44075867_- | SINE | Alu | Name=AluJb |
| ADediting_1332888 | chr7_44075877_- | SINE | Alu | Name=AluJb |
| ADediting_1332889 | chr7_44075892_- | SINE | Alu | Name=AluJb |
| ADediting_1332890 | chr7_44075903_- | SINE | Alu | Name=AluJb |
| ADediting_1332891 | chr7_44075921_- | SINE | Alu | Name=AluJb |
| ADediting_1332892 | chr7_44075957_- | SINE | Alu | Name=AluJb |
| ADediting_1332893 | chr7_44075958_- | SINE | Alu | Name=AluJb |
| ADediting_1332894 | chr7_44075966_- | SINE | Alu | Name=AluJb |
| ADediting_1332895 | chr7_44075971_- | SINE | Alu | Name=AluJb |
| ADediting_1332896 | chr7_44075990_- | SINE | Alu | Name=AluJb |
| ADediting_1332897 | chr7_44076018_- | SINE | Alu | Name=AluJb |
| ADediting_1332898 | chr7_44078201_- | SINE | Alu | Name=AluJr |
| ADediting_1332899 | chr7_44078218_- | SINE | Alu | Name=AluJr |
| ADediting_1332900 | chr7_44078219_- | SINE | Alu | Name=AluJr |
| ADediting_1332901 | chr7_44078244_- | SINE | Alu | Name=AluJr |
| ADediting_1332902 | chr7_44078245_- | SINE | Alu | Name=AluJr |
| ADediting_1332903 | chr7_44078252_- | SINE | Alu | Name=AluJr |
| ADediting_1332904 | chr7_44078260_- | SINE | Alu | Name=AluJr |
| ADediting_1332905 | chr7_44078270_- | SINE | Alu | Name=AluJr |
| ADediting_1332906 | chr7_44078297_- | SINE | Alu | Name=AluJr |
| ADediting_1332907 | chr7_44078298_- | SINE | Alu | Name=AluJr |
| ADediting_1332908 | chr7_44078326_- | SINE | Alu | Name=AluJr |
| ADediting_1332909 | chr7_44078338_- | SINE | Alu | Name=AluJr |
| ADediting_1332910 | chr7_44078342_- | SINE | Alu | Name=AluJr |
| ADediting_1332911 | chr7_44078344_- | SINE | Alu | Name=AluJr |
| ADediting_1332912 | chr7_44078347_- | SINE | Alu | Name=AluJr |
| ADediting_1332913 | chr7_44078354_- | SINE | Alu | Name=AluJr |
| ADediting_1332914 | chr7_44078366_- | SINE | Alu | Name=AluJr |
| ADediting_1332915 | chr7_44078371_- | SINE | Alu | Name=AluJr |
| ADediting_1332916 | chr7_44078382_- | SINE | Alu | Name=AluJr |
| ADediting_1332917 | chr7_44078383_- | SINE | Alu | Name=AluJr |
| ADediting_1332918 | chr7_44078384_- | SINE | Alu | Name=AluJr |
| ADediting_1332919 | chr7_44078409_- | SINE | Alu | Name=AluJr |
| ADediting_1332920 | chr7_44078430_- | SINE | Alu | Name=AluJr |
| ADediting_1332921 | chr7_44078460_- | SINE | Alu | Name=AluJr |
| ADediting_1332922 | chr7_44078464_- | SINE | Alu | Name=AluJr |
| ADediting_1587519 | chr7_44075072_- | SINE | Alu | Name=AluSq |
| ADediting_1587520 | chr7_44075089_- | SINE | Alu | Name=AluSq |
| ADediting_1587521 | chr7_44075123_- | SINE | Alu | Name=AluSq |
| ADediting_1587522 | chr7_44075147_- | SINE | Alu | Name=AluSq |
| ADediting_1587523 | chr7_44075277_- | SINE | Alu | Name=AluSq |
| ADediting_1587524 | chr7_44075750_- | SINE | Alu | Name=AluJb |
| ADediting_1587525 | chr7_44075854_- | SINE | Alu | Name=AluJb |
| ADediting_1587526 | chr7_44075885_- | SINE | Alu | Name=AluJb |
| ADediting_1587527 | chr7_44075932_- | SINE | Alu | Name=AluJb |
| ADediting_1587528 | chr7_44075989_- | SINE | Alu | Name=AluJb |
| ADediting_1587529 | chr7_44076003_- | SINE | Alu | Name=AluJb |
| ADediting_1587530 | chr7_44078259_- | SINE | Alu | Name=AluJr |
| ADediting_1587531 | chr7_44078440_- | SINE | Alu | Name=AluJr |
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RNA A-to-I editing events in the alternative splicing sites for POLM |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for POLM |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for POLM |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for POLM |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1556067 | chr19_40282625_- | ENSG00000122678.17 | ENST00000242248.10 | POLM-201 | hsa-miR-641 | chr7 | 44072642 | 44072649 | 8mer-1a | 44072642 | 44072665 | 149 | -15.32 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000122678.17 | ENST00000242248.10 | POLM-201 | hsa-miR-641 | chr7 | 44072928 | 44072934 | 7mer-1a | 44072928 | 44072952 | 141 | -16.28 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000122678.17 | ENST00000242248.10 | POLM-201 | hsa-miR-641 | chr7 | 44073224 | 44073230 | 7mer-m8 | 44073223 | 44073246 | 140 | -13.48 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000122678.17 | ENST00000335195.10 | POLM-202 | hsa-miR-641 | chr7 | 44072642 | 44072649 | 8mer-1a | 44072642 | 44072665 | 149 | -15.32 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000122678.17 | ENST00000335195.10 | POLM-202 | hsa-miR-641 | chr7 | 44072928 | 44072934 | 7mer-1a | 44072928 | 44072952 | 141 | -16.28 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000122678.17 | ENST00000335195.10 | POLM-202 | hsa-miR-641 | chr7 | 44073224 | 44073230 | 7mer-m8 | 44073223 | 44073246 | 140 | -13.48 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000122678.17 | ENST00000395831.7 | POLM-203 | hsa-miR-641 | chr7 | 44072642 | 44072649 | 8mer-1a | 44072642 | 44072665 | 149 | -15.32 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000122678.17 | ENST00000395831.7 | POLM-203 | hsa-miR-641 | chr7 | 44072928 | 44072934 | 7mer-1a | 44072928 | 44072952 | 141 | -16.28 |
| ADediting_496066 | chr15_66496985_- | ENSG00000122678.17 | ENST00000242248.10 | POLM-201 | hsa-miR-4512 | chr7 | 44072489 | 44072495 | 7mer-m8 | 44072488 | 44072509 | 158 | -22.47 |
| ADediting_496066 | chr15_66496985_- | ENSG00000122678.17 | ENST00000335195.10 | POLM-202 | hsa-miR-4512 | chr7 | 44072489 | 44072495 | 7mer-m8 | 44072488 | 44072509 | 158 | -22.47 |
| ADediting_496066 | chr15_66496985_- | ENSG00000122678.17 | ENST00000395831.7 | POLM-203 | hsa-miR-4512 | chr7 | 44072489 | 44072495 | 7mer-m8 | 44072488 | 44072509 | 158 | -22.47 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1643790 | chr3_121049689_+ | ENSG00000122678.17 | ENST00000242248.10 | POLM-201 | hsa-miR-5682 | chr7 | 44072126 | 44072132 | 7mer-m8 | 44072125 | 44072146 | 142 | -17.75 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for POLM |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for POLM |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_1332893 | chr7_44075958_- | 4.21763755577825e-06 | 0.365590113598775 | 5.71865159732625e-06 | 0.360866170694216 | 0.125586783099927 | 0.125620896082518 |
| CER | ADediting_1332894 | chr7_44075966_- | 8.6104147819046e-06 | 0.354395713585942 | 1.50717695488311e-06 | 0.381026147905669 | 0.768226927209571 | 0.0242611546317877 |
| DLPFC | ADediting_1332910 | chr7_44078342_- | 0.231632257723202 | 0.068133865708321 | 0.389797646016617 | -0.0490124680491691 | 6.37347269653634e-15 | 0.423500520473283 |
| TCX | ADediting_1332910 | chr7_44078342_- | 0.63290264251946 | 0.0393133718787496 | 0.575441188459842 | -0.0460896365720873 | 1.68130823885489e-05 | 0.34349962335534 |
| DLPFC | ADediting_1332911 | chr7_44078344_- | 0.243350285841366 | 0.0664566662355549 | 0.507963332538081 | -0.0377388317157264 | 5.82289423229426e-13 | 0.39410418361936 |
| TCX | ADediting_1332911 | chr7_44078344_- | 0.856301157195814 | -0.0149093996222523 | 0.147480530020738 | -0.118843191018024 | 2.78166595813466e-06 | 0.371929603883341 |
| CER | ADediting_1332913 | chr7_44078354_- | 0.00454027322556514 | 0.230517769843591 | 3.63252049652012e-05 | 0.330431157199571 | 0.631153360185306 | 0.039515586423768 |
| TCX | ADediting_1332913 | chr7_44078354_- | 0.343605997395137 | 0.0778613566429448 | 0.127488929810218 | -0.124997625574243 | 2.90215691111322e-07 | 0.404205977143898 |
| DLPFC | ADediting_1332914 | chr7_44078366_- | 0.100835992729938 | 0.093365492576291 | 0.974401674872501 | 0.00182988080863901 | 9.98957325999988e-12 | 0.373984326362208 |
| TCX | ADediting_1332914 | chr7_44078366_- | 0.149866592914596 | 0.118151888397544 | 0.136326380486219 | -0.122192230623137 | 2.76192473427732e-07 | 0.404876289253356 |
| TCX | ADediting_1332915 | chr7_44078371_- | 0.0955226491098643 | 0.13661053801586 | 0.271167823466107 | -0.0904176348240679 | 9.78547745403887e-07 | 0.387276739329457 |
| CER | ADediting_1332919 | chr7_44078409_- | 0.00675047132182135 | 0.220300320755192 | 0.000152107504657175 | 0.30442985838347 | 0.169754577629085 | 0.112689668662901 |
| DLPFC | ADediting_1332920 | chr7_44078430_- | 0.014491949147677 | 0.138745411490632 | 0.936497162297591 | -0.00454346574848691 | 7.18939527661615e-17 | 0.450112269919777 |
| CER | ADediting_1332920 | chr7_44078430_- | 1.84907658529842e-05 | 0.341917514886409 | 7.60078202006666e-06 | 0.356382691109738 | 0.46721398635668 | 0.0598080519775658 |
| TCX | ADediting_1332920 | chr7_44078430_- | 0.380843729780769 | 0.0720628393824292 | 0.579337586041227 | -0.0456207590073133 | 3.71106565322131e-06 | 0.367553346340671 |
| CER | ADediting_1587528 | chr7_44075989_- | 4.34363476716425e-06 | 0.365136638371679 | 1.85976113285885e-07 | 0.410176939696744 | 0.102511504431223 | 0.133836510848094 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 1.08680999700055e-19 | 0.484943542543806 | 1.03111456462969e-19 | 0.485210062167608 | 3.76726336458905e-28 | 0.570397633360184 |
| AC | 9.09478535523853e-18 | 0.507465838489677 | 1.87681154123941e-10 | 0.38891753629187 | 7.36385755849429e-31 | 0.645485207653211 |
| PCC | 3.90536546025112e-08 | 0.384724736782753 | 5.820278373344e-06 | 0.321351000042053 | 6.0644392203332e-10 | 0.428795590843578 |
| CER | 5.34355060503124e-08 | 0.426318154438517 | 0.0109410559067531 | 0.207236794137815 | 0.639225661882495 | -0.0385843853656674 |
| TCX | 1.26749820474534e-05 | 0.348149291150478 | 0.479733823977463 | -0.0581418660802338 | 7.39772248593082e-18 | 0.628404957986143 |
| FP | 4.64915280925147e-09 | 0.421504214594506 | 0.0103883150302433 | 0.191643573287647 | 4.67563529387492e-16 | 0.559590131737003 |
| IFG | 0.0136413564649292 | 0.486591311188678 | 0.0205054403009311 | 0.460581712022988 | 0.00764843371337922 | 0.520460260138465 |
| PG | 0.88448721724987 | 0.0107246787997212 | 0.693240528589161 | -0.0291134322909802 | 9.40881399471163e-14 | 0.510810142223488 |
| STG | 0.0840417656352011 | 0.189634563093316 | 0.745293915063566 | -0.0359716601527904 | 7.94415750931777e-07 | 0.50835859022822 |
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Relation with AD stages for POLM |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_1332877 | chr7_44075188_- | 0.000977636939034007 | 0.312879218276371 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| TCX | 2.76984514798375e-07 | 0.474495586602943 |
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RelatedDrugs for POLM |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for POLM |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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