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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for GIPR |
 Gene summary |
| Gene information | Gene symbol | GIPR | Gene ID | 2696 |
| Gene name | gastric inhibitory polypeptide receptor | |
| Synonyms | PGQTL2 | |
| Cytomap | 19q13.32 | |
| Type of gene | protein-coding | |
| Description | gastric inhibitory polypeptide receptorGIP-Rglucose-dependent insulinotropic polypeptide receptor | |
| Modification date | 20200313 | |
| UniProtAcc | P48546, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for GIPR |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_763061(45669828, +), ADediting_763062(45669829, +), ADediting_763063(45669855, +), ADediting_763064(45669869, +), ADediting_763065(45669881, +), ADediting_763066(45669894, +), ADediting_763067(45669920, +), ADediting_763068(45670092, +), ADediting_763069(45670131, +), ADediting_763070(45670148, +), ADediting_763071(45670160, +), ADediting_763072(45670170, +), ADediting_763073(45670266, +), ADediting_763074(45670267, +), ADediting_763075(45670293, +), ADediting_763076(45675305, +), ADediting_763077(45675315, +), ADediting_763078(45675343, +), ADediting_763079(45675352, +), ADediting_763080(45675428, +), ADediting_763081(45675468, +), ADediting_763082(45675507, +), ADediting_763083(45675661, +), ADediting_763084(45675705, +), ADediting_763085(45675722, +), ADediting_763086(45675934, +), ADediting_763087(45675951, +), ADediting_763088(45675956, +), ADediting_763089(45676022, +), ADediting_763090(45676039, +), ADediting_763091(45676042, +), ADediting_763092(45676096, +), ADediting_763093(45676115, +), ADediting_763094(45676118, +), ADediting_763095(45676135, +), ADediting_763096(45676144, +), ADediting_763097(45676498, +), ADediting_763098(45676513, +), ADediting_763099(45676534, +), ADediting_763100(45676551, +), ADediting_763101(45676563, +), ADediting_763102(45676608, +), ADediting_763103(45676617, +), ADediting_763104(45676623, +), ADediting_763105(45676631, +), ADediting_763106(45676634, +), ADediting_763107(45676696, +), ADediting_763108(45678417, +), ADediting_763109(45678443, +), ADediting_763110(45678463, +), ADediting_763111(45678481, +), ADediting_763112(45678493, +), ADediting_763113(45678543, +), ADediting_763114(45678546, +), ADediting_763115(45678548, +), ADediting_763116(45678591, +), ADediting_763117(45678601, +), ADediting_763118(45678625, +), ADediting_763119(45679218, +), ADediting_763120(45679224, +), ADediting_763121(45679251, +), ADediting_763122(45679271, +), ADediting_763123(45679290, +), ADediting_763124(45679423, +), ADediting_763125(45679437, +), ADediting_763126(45679706, +), ADediting_763127(45679710, +), ADediting_763128(45679826, +), ADediting_763129(45679839, +), ADediting_763130(45679856, +), ADediting_763131(45679887, +), ADediting_763132(45679895, +), ADediting_763133(45680197, +), ADediting_763134(45680406, +), ADediting_763135(45680430, +), ADediting_763136(45680447, +), ADediting_763137(45680668, +), ADediting_763138(45681217, +), ADediting_763139(45681239, +), ADediting_763140(45681240, +), ADediting_763141(45681278, +), ADediting_763142(45681285, +), ADediting_763143(45681333, +), ADediting_763144(45681348, +), ADediting_763145(45681398, +), ADediting_763146(45681410, +), ADediting_763147(45682527, +), ADediting_763148(45682625, +), ADediting_763149(45682630, +), ADediting_763150(45682683, +), ADediting_763151(45682805, +), ADediting_763152(45682817, +), ADediting_1556769(45675303, +), ADediting_1556770(45678503, +), ADediting_1556771(45679620, +), ADediting_1556772(45679732, +), ADediting_1556773(45679909, +), ADediting_1556774(45680241, +), ADediting_1556775(45680312, +), ADediting_1556776(45680645, +), ADediting_1556777(45681339, +), ADediting_1556778(45681407, +), |
Top |
RNA editing positional annotations for GIPR using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_763061 | chr19_45669828_+ | intronic |
| ADediting_763062 | chr19_45669829_+ | intronic |
| ADediting_763063 | chr19_45669855_+ | intronic |
| ADediting_763064 | chr19_45669869_+ | intronic |
| ADediting_763065 | chr19_45669881_+ | intronic |
| ADediting_763066 | chr19_45669894_+ | intronic |
| ADediting_763067 | chr19_45669920_+ | intronic |
| ADediting_763068 | chr19_45670092_+ | intronic |
| ADediting_763069 | chr19_45670131_+ | intronic |
| ADediting_763070 | chr19_45670148_+ | intronic |
| ADediting_763071 | chr19_45670160_+ | intronic |
| ADediting_763072 | chr19_45670170_+ | intronic |
| ADediting_763073 | chr19_45670266_+ | UTR5 |
| ADediting_763074 | chr19_45670267_+ | UTR5 |
| ADediting_763075 | chr19_45670293_+ | UTR5 |
| ADediting_763076 | chr19_45675305_+ | intronic |
| ADediting_763077 | chr19_45675315_+ | intronic |
| ADediting_763078 | chr19_45675343_+ | intronic |
| ADediting_763079 | chr19_45675352_+ | intronic |
| ADediting_763080 | chr19_45675428_+ | intronic |
| ADediting_763081 | chr19_45675468_+ | intronic |
| ADediting_763082 | chr19_45675507_+ | intronic |
| ADediting_763083 | chr19_45675661_+ | intronic |
| ADediting_763084 | chr19_45675705_+ | intronic |
| ADediting_763085 | chr19_45675722_+ | intronic |
| ADediting_763086 | chr19_45675934_+ | intronic |
| ADediting_763087 | chr19_45675951_+ | intronic |
| ADediting_763088 | chr19_45675956_+ | intronic |
| ADediting_763089 | chr19_45676022_+ | intronic |
| ADediting_763090 | chr19_45676039_+ | intronic |
| ADediting_763091 | chr19_45676042_+ | intronic |
| ADediting_763092 | chr19_45676096_+ | intronic |
| ADediting_763093 | chr19_45676115_+ | intronic |
| ADediting_763094 | chr19_45676118_+ | intronic |
| ADediting_763095 | chr19_45676135_+ | intronic |
| ADediting_763096 | chr19_45676144_+ | intronic |
| ADediting_763097 | chr19_45676498_+ | intronic |
| ADediting_763098 | chr19_45676513_+ | intronic |
| ADediting_763099 | chr19_45676534_+ | intronic |
| ADediting_763100 | chr19_45676551_+ | intronic |
| ADediting_763101 | chr19_45676563_+ | intronic |
| ADediting_763102 | chr19_45676608_+ | intronic |
| ADediting_763103 | chr19_45676617_+ | intronic |
| ADediting_763104 | chr19_45676623_+ | intronic |
| ADediting_763105 | chr19_45676631_+ | intronic |
| ADediting_763106 | chr19_45676634_+ | intronic |
| ADediting_763107 | chr19_45676696_+ | intronic |
| ADediting_763108 | chr19_45678417_+ | intronic |
| ADediting_763109 | chr19_45678443_+ | intronic |
| ADediting_763110 | chr19_45678463_+ | intronic |
| ADediting_763111 | chr19_45678481_+ | intronic |
| ADediting_763112 | chr19_45678493_+ | intronic |
| ADediting_763113 | chr19_45678543_+ | intronic |
| ADediting_763114 | chr19_45678546_+ | intronic |
| ADediting_763115 | chr19_45678548_+ | intronic |
| ADediting_763116 | chr19_45678591_+ | intronic |
| ADediting_763117 | chr19_45678601_+ | intronic |
| ADediting_763118 | chr19_45678625_+ | intronic |
| ADediting_763119 | chr19_45679218_+ | intronic |
| ADediting_763120 | chr19_45679224_+ | intronic |
| ADediting_763121 | chr19_45679251_+ | intronic |
| ADediting_763122 | chr19_45679271_+ | intronic |
| ADediting_763123 | chr19_45679290_+ | intronic |
| ADediting_763124 | chr19_45679423_+ | intronic |
| ADediting_763125 | chr19_45679437_+ | intronic |
| ADediting_763126 | chr19_45679706_+ | intronic |
| ADediting_763127 | chr19_45679710_+ | intronic |
| ADediting_763128 | chr19_45679826_+ | intronic |
| ADediting_763129 | chr19_45679839_+ | intronic |
| ADediting_763130 | chr19_45679856_+ | intronic |
| ADediting_763131 | chr19_45679887_+ | intronic |
| ADediting_763132 | chr19_45679895_+ | intronic |
| ADediting_763133 | chr19_45680197_+ | intronic |
| ADediting_763134 | chr19_45680406_+ | intronic |
| ADediting_763135 | chr19_45680430_+ | intronic |
| ADediting_763136 | chr19_45680447_+ | intronic |
| ADediting_763137 | chr19_45680668_+ | intronic |
| ADediting_763138 | chr19_45681217_+ | intronic |
| ADediting_763139 | chr19_45681239_+ | intronic |
| ADediting_763140 | chr19_45681240_+ | intronic |
| ADediting_763141 | chr19_45681278_+ | intronic |
| ADediting_763142 | chr19_45681285_+ | intronic |
| ADediting_763143 | chr19_45681333_+ | intronic |
| ADediting_763144 | chr19_45681348_+ | intronic |
| ADediting_763145 | chr19_45681398_+ | intronic |
| ADediting_763146 | chr19_45681410_+ | intronic |
| ADediting_763147 | chr19_45682527_+ | UTR3 |
| ADediting_763148 | chr19_45682625_+ | UTR3 |
| ADediting_763149 | chr19_45682630_+ | UTR3 |
| ADediting_763150 | chr19_45682683_+ | UTR3 |
| ADediting_763151 | chr19_45682805_+ | UTR3 |
| ADediting_763152 | chr19_45682817_+ | UTR3 |
| ADediting_1556769 | chr19_45675303_+ | intronic |
| ADediting_1556770 | chr19_45678503_+ | intronic |
| ADediting_1556771 | chr19_45679620_+ | intronic |
| ADediting_1556772 | chr19_45679732_+ | intronic |
| ADediting_1556773 | chr19_45679909_+ | intronic |
| ADediting_1556774 | chr19_45680241_+ | intronic |
| ADediting_1556775 | chr19_45680312_+ | intronic |
| ADediting_1556776 | chr19_45680645_+ | intronic |
| ADediting_1556777 | chr19_45681339_+ | intronic |
| ADediting_1556778 | chr19_45681407_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_763061 | chr19_45669828_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763062 | chr19_45669829_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763063 | chr19_45669855_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763064 | chr19_45669869_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763065 | chr19_45669881_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763066 | chr19_45669894_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763067 | chr19_45669920_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763068 | chr19_45670092_+ | SINE | Alu | Name=AluSz |
| ADediting_763069 | chr19_45670131_+ | SINE | Alu | Name=AluSz |
| ADediting_763070 | chr19_45670148_+ | SINE | Alu | Name=AluSz |
| ADediting_763071 | chr19_45670160_+ | SINE | Alu | Name=AluSz |
| ADediting_763072 | chr19_45670170_+ | SINE | Alu | Name=AluSz |
| ADediting_763073 | chr19_45670266_+ | SINE | Alu | Name=AluSz |
| ADediting_763074 | chr19_45670267_+ | SINE | Alu | Name=AluSz |
| ADediting_763075 | chr19_45670293_+ | SINE | Alu | Name=AluSz |
| ADediting_763076 | chr19_45675305_+ | SINE | Alu | Name=AluSx4 |
| ADediting_763077 | chr19_45675315_+ | SINE | Alu | Name=AluSx4 |
| ADediting_763078 | chr19_45675343_+ | SINE | Alu | Name=AluSx4 |
| ADediting_763079 | chr19_45675352_+ | SINE | Alu | Name=AluSx4 |
| ADediting_763080 | chr19_45675428_+ | SINE | Alu | Name=AluSx4 |
| ADediting_763081 | chr19_45675468_+ | SINE | Alu | Name=AluSx4 |
| ADediting_763082 | chr19_45675507_+ | SINE | Alu | Name=AluSx4 |
| ADediting_763083 | chr19_45675661_+ | SINE | Alu | Name=AluJo |
| ADediting_763084 | chr19_45675705_+ | SINE | Alu | Name=AluJo |
| ADediting_763085 | chr19_45675722_+ | SINE | Alu | Name=AluJo |
| ADediting_763086 | chr19_45675934_+ | SINE | Alu | Name=AluSg |
| ADediting_763087 | chr19_45675951_+ | SINE | Alu | Name=AluSg |
| ADediting_763088 | chr19_45675956_+ | SINE | Alu | Name=AluSg |
| ADediting_763089 | chr19_45676022_+ | SINE | Alu | Name=AluSg |
| ADediting_763090 | chr19_45676039_+ | SINE | Alu | Name=AluSg |
| ADediting_763091 | chr19_45676042_+ | SINE | Alu | Name=AluSg |
| ADediting_763092 | chr19_45676096_+ | SINE | Alu | Name=AluSg |
| ADediting_763093 | chr19_45676115_+ | SINE | Alu | Name=AluSg |
| ADediting_763094 | chr19_45676118_+ | SINE | Alu | Name=AluSg |
| ADediting_763095 | chr19_45676135_+ | SINE | Alu | Name=AluSg |
| ADediting_763096 | chr19_45676144_+ | SINE | Alu | Name=AluSg |
| ADediting_763097 | chr19_45676498_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763098 | chr19_45676513_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763099 | chr19_45676534_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763100 | chr19_45676551_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763101 | chr19_45676563_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763102 | chr19_45676608_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763103 | chr19_45676617_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763104 | chr19_45676623_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763105 | chr19_45676631_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763106 | chr19_45676634_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763107 | chr19_45676696_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763108 | chr19_45678417_+ | SINE | Alu | Name=AluSx |
| ADediting_763109 | chr19_45678443_+ | SINE | Alu | Name=AluSx |
| ADediting_763110 | chr19_45678463_+ | SINE | Alu | Name=AluSx |
| ADediting_763111 | chr19_45678481_+ | SINE | Alu | Name=AluSx |
| ADediting_763112 | chr19_45678493_+ | SINE | Alu | Name=AluSx |
| ADediting_763113 | chr19_45678543_+ | SINE | Alu | Name=AluSx |
| ADediting_763114 | chr19_45678546_+ | SINE | Alu | Name=AluSx |
| ADediting_763115 | chr19_45678548_+ | SINE | Alu | Name=AluSx |
| ADediting_763116 | chr19_45678591_+ | SINE | Alu | Name=AluSx |
| ADediting_763117 | chr19_45678601_+ | SINE | Alu | Name=AluSx |
| ADediting_763118 | chr19_45678625_+ | SINE | Alu | Name=AluSx |
| ADediting_763119 | chr19_45679218_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763120 | chr19_45679224_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763121 | chr19_45679251_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763122 | chr19_45679271_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763123 | chr19_45679290_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763124 | chr19_45679423_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763125 | chr19_45679437_+ | SINE | Alu | Name=AluSx1 |
| ADediting_763126 | chr19_45679706_+ | SINE | Alu | Name=AluJo |
| ADediting_763127 | chr19_45679710_+ | SINE | Alu | Name=AluJo |
| ADediting_763128 | chr19_45679826_+ | SINE | Alu | Name=AluSq2 |
| ADediting_763129 | chr19_45679839_+ | SINE | Alu | Name=AluSq2 |
| ADediting_763130 | chr19_45679856_+ | SINE | Alu | Name=AluSq2 |
| ADediting_763131 | chr19_45679887_+ | SINE | Alu | Name=AluSq2 |
| ADediting_763132 | chr19_45679895_+ | SINE | Alu | Name=AluSq2 |
| ADediting_763133 | chr19_45680197_+ | SINE | Alu | Name=AluSg |
| ADediting_763134 | chr19_45680406_+ | SINE | Alu | Name=AluJr |
| ADediting_763135 | chr19_45680430_+ | SINE | Alu | Name=AluJr |
| ADediting_763136 | chr19_45680447_+ | SINE | Alu | Name=AluJr |
| ADediting_763137 | chr19_45680668_+ | SINE | Alu | Name=AluSx |
| ADediting_763138 | chr19_45681217_+ | SINE | Alu | Name=AluSq |
| ADediting_763139 | chr19_45681239_+ | SINE | Alu | Name=AluSq |
| ADediting_763140 | chr19_45681240_+ | SINE | Alu | Name=AluSq |
| ADediting_763141 | chr19_45681278_+ | SINE | Alu | Name=AluSq |
| ADediting_763142 | chr19_45681285_+ | SINE | Alu | Name=AluSq |
| ADediting_763143 | chr19_45681333_+ | SINE | Alu | Name=AluSq |
| ADediting_763144 | chr19_45681348_+ | SINE | Alu | Name=AluSq |
| ADediting_763145 | chr19_45681398_+ | SINE | Alu | Name=AluSq |
| ADediting_763146 | chr19_45681410_+ | SINE | Alu | Name=AluSq |
| ADediting_763147 | chr19_45682527_+ | SINE | Alu | Name=AluJo |
| ADediting_763148 | chr19_45682625_+ | SINE | Alu | Name=AluSz |
| ADediting_763149 | chr19_45682630_+ | SINE | Alu | Name=AluSz |
| ADediting_763150 | chr19_45682683_+ | SINE | Alu | Name=AluSz |
| ADediting_763151 | chr19_45682805_+ | SINE | Alu | Name=AluSz |
| ADediting_763152 | chr19_45682817_+ | SINE | Alu | Name=AluSz |
| ADediting_1556769 | chr19_45675303_+ | SINE | Alu | Name=AluSx4 |
| ADediting_1556770 | chr19_45678503_+ | SINE | Alu | Name=AluSx |
| ADediting_1556771 | chr19_45679620_+ | SINE | Alu | Name=AluJo |
| ADediting_1556772 | chr19_45679732_+ | SINE | Alu | Name=AluJo |
| ADediting_1556773 | chr19_45679909_+ | SINE | Alu | Name=AluSq2 |
| ADediting_1556774 | chr19_45680241_+ | SINE | Alu | Name=AluSg |
| ADediting_1556775 | chr19_45680312_+ | SINE | Alu | Name=AluSg |
| ADediting_1556776 | chr19_45680645_+ | SINE | Alu | Name=AluSx |
| ADediting_1556777 | chr19_45681339_+ | SINE | Alu | Name=AluSq |
| ADediting_1556778 | chr19_45681407_+ | SINE | Alu | Name=AluSq |
Top |
RNA A-to-I editing events in the alternative splicing sites for GIPR |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for GIPR |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for GIPR |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for GIPR |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_763148 | chr19_45682625_+ | ENSG00000010310.9 | ENST00000590918.6 | GIPR-205 | hsa-miR-3130-3p | chr19 | 45682618 | 45682624 | 7mer-m8 | 45682604 | 45682625 | 146 | -18.52 |
| ADediting_763148 | chr19_45682625_+ | ENSG00000010310.9 | ENST00000590918.6 | GIPR-205 | hsa-miR-4738-3p | chr19 | 45682622 | 45682629 | 8mer-1a | 45682609 | 45682629 | 153 | -18.57 |
| ADediting_763148 | chr19_45682625_+ | ENSG00000010310.9 | ENST00000590918.6 | GIPR-205 | hsa-miR-548av-3p | chr19 | 45682621 | 45682627 | 7mer-m8 | 45682610 | 45682628 | 153 | -13.58 |
| ADediting_763148 | chr19_45682625_+ | ENSG00000010310.9 | ENST00000652180.1 | GIPR-209 | hsa-miR-3130-3p | chr19 | 45682618 | 45682624 | 7mer-m8 | 45682604 | 45682625 | 146 | -18.52 |
| ADediting_763148 | chr19_45682625_+ | ENSG00000010310.9 | ENST00000652180.1 | GIPR-209 | hsa-miR-4738-3p | chr19 | 45682622 | 45682629 | 8mer-1a | 45682609 | 45682629 | 153 | -18.57 |
| ADediting_763148 | chr19_45682625_+ | ENSG00000010310.9 | ENST00000652180.1 | GIPR-209 | hsa-miR-548av-3p | chr19 | 45682621 | 45682627 | 7mer-m8 | 45682610 | 45682628 | 153 | -13.58 |
| ADediting_763149 | chr19_45682630_+ | ENSG00000010310.9 | ENST00000590918.6 | GIPR-205 | hsa-miR-4537 | chr19 | 45682627 | 45682634 | 8mer-1a | 45682613 | 45682634 | 143 | -23.22 |
| ADediting_763149 | chr19_45682630_+ | ENSG00000010310.9 | ENST00000652180.1 | GIPR-209 | hsa-miR-4537 | chr19 | 45682627 | 45682634 | 8mer-1a | 45682613 | 45682634 | 143 | -23.22 |
| ADediting_763151 | chr19_45682805_+ | ENSG00000010310.9 | ENST00000590918.6 | GIPR-205 | hsa-miR-3189-3p | chr19 | 45682799 | 45682805 | 7mer-m8 | 45682783 | 45682806 | 157 | -25.36 |
| ADediting_763151 | chr19_45682805_+ | ENSG00000010310.9 | ENST00000590918.6 | GIPR-205 | hsa-miR-6813-3p | chr19 | 45682800 | 45682806 | 7mer-m8 | 45682787 | 45682807 | 140 | -10.68 |
| ADediting_763151 | chr19_45682805_+ | ENSG00000010310.9 | ENST00000652180.1 | GIPR-209 | hsa-miR-3189-3p | chr19 | 45682799 | 45682805 | 7mer-m8 | 45682783 | 45682806 | 157 | -25.36 |
| ADediting_763151 | chr19_45682805_+ | ENSG00000010310.9 | ENST00000652180.1 | GIPR-209 | hsa-miR-6813-3p | chr19 | 45682800 | 45682806 | 7mer-m8 | 45682787 | 45682807 | 140 | -10.68 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_763148 | chr19_45682625_+ | ENSG00000010310.9 | ENST00000590918.6 | GIPR-205 | hsa-miR-25-3p | chr19 | 45682619 | 45682625 | 7mer-m8 | 45682601 | 45682626 | 153 | -24.46 |
| ADediting_763148 | chr19_45682625_+ | ENSG00000010310.9 | ENST00000590918.6 | GIPR-205 | hsa-miR-32-5p | chr19 | 45682619 | 45682625 | 7mer-m8 | 45682604 | 45682626 | 144 | -13.63 |
| ADediting_763148 | chr19_45682625_+ | ENSG00000010310.9 | ENST00000590918.6 | GIPR-205 | hsa-miR-363-3p | chr19 | 45682619 | 45682625 | 7mer-m8 | 45682600 | 45682626 | 149 | -20.53 |
| ADediting_763148 | chr19_45682625_+ | ENSG00000010310.9 | ENST00000590918.6 | GIPR-205 | hsa-miR-367-3p | chr19 | 45682619 | 45682625 | 7mer-m8 | 45682605 | 45682626 | 153 | -17.21 |
| ADediting_763148 | chr19_45682625_+ | ENSG00000010310.9 | ENST00000590918.6 | GIPR-205 | hsa-miR-92b-3p | chr19 | 45682619 | 45682625 | 7mer-m8 | 45682601 | 45682626 | 155 | -23.9 |
| ADediting_763148 | chr19_45682625_+ | ENSG00000010310.9 | ENST00000652180.1 | GIPR-209 | hsa-miR-25-3p | chr19 | 45682619 | 45682625 | 7mer-m8 | 45682601 | 45682626 | 153 | -24.46 |
| ADediting_763148 | chr19_45682625_+ | ENSG00000010310.9 | ENST00000652180.1 | GIPR-209 | hsa-miR-32-5p | chr19 | 45682619 | 45682625 | 7mer-m8 | 45682604 | 45682626 | 144 | -13.63 |
| ADediting_763148 | chr19_45682625_+ | ENSG00000010310.9 | ENST00000652180.1 | GIPR-209 | hsa-miR-363-3p | chr19 | 45682619 | 45682625 | 7mer-m8 | 45682600 | 45682626 | 149 | -20.53 |
| ADediting_763148 | chr19_45682625_+ | ENSG00000010310.9 | ENST00000652180.1 | GIPR-209 | hsa-miR-367-3p | chr19 | 45682619 | 45682625 | 7mer-m8 | 45682605 | 45682626 | 153 | -17.21 |
| ADediting_763148 | chr19_45682625_+ | ENSG00000010310.9 | ENST00000652180.1 | GIPR-209 | hsa-miR-92b-3p | chr19 | 45682619 | 45682625 | 7mer-m8 | 45682601 | 45682626 | 155 | -23.9 |
| ADediting_763149 | chr19_45682630_+ | ENSG00000010310.9 | ENST00000590918.6 | GIPR-205 | hsa-miR-3160-3p | chr19 | 45682627 | 45682634 | 8mer-1a | 45682613 | 45682634 | 148 | -15.37 |
| ADediting_763149 | chr19_45682630_+ | ENSG00000010310.9 | ENST00000652180.1 | GIPR-209 | hsa-miR-3160-3p | chr19 | 45682627 | 45682634 | 8mer-1a | 45682613 | 45682634 | 148 | -15.37 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_286380 | chr11_79422188_- | ENSG00000010310.9 | ENST00000590918.6 | GIPR-205 | hsa-miR-5579-3p | chr19 | 45682195 | 45682201 | 7mer-m8 | 45682181 | 45682202 | 157 | -20.66 |
| ADediting_286380 | chr11_79422188_- | ENSG00000010310.9 | ENST00000590918.6 | GIPR-205 | hsa-miR-5579-3p | chr19 | 45682823 | 45682829 | 7mer-m8 | 45682805 | 45682830 | 149 | -15.26 |
| ADediting_286380 | chr11_79422188_- | ENSG00000010310.9 | ENST00000652180.1 | GIPR-209 | hsa-miR-5579-3p | chr19 | 45682195 | 45682201 | 7mer-m8 | 45682181 | 45682202 | 157 | -20.66 |
| ADediting_286380 | chr11_79422188_- | ENSG00000010310.9 | ENST00000652180.1 | GIPR-209 | hsa-miR-5579-3p | chr19 | 45682823 | 45682829 | 7mer-m8 | 45682805 | 45682830 | 149 | -15.26 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_107020 | chr1_37500952_- | ENSG00000010310.9 | ENST00000263281.7 | GIPR-201 | hsa-miR-5581-3p | chr19 | 45681964 | 45681970 | 7mer-m8 | 45681951 | 45681971 | 147 | -12.87 |
| ADediting_107020 | chr1_37500952_- | ENSG00000010310.9 | ENST00000304207.12 | GIPR-202 | hsa-miR-5581-3p | chr19 | 45681964 | 45681970 | 7mer-m8 | 45681951 | 45681971 | 147 | -12.87 |
| ADediting_107020 | chr1_37500952_- | ENSG00000010310.9 | ENST00000590918.6 | GIPR-205 | hsa-miR-5581-3p | chr19 | 45681964 | 45681970 | 7mer-m8 | 45681951 | 45681971 | 147 | -12.87 |
| ADediting_107020 | chr1_37500952_- | ENSG00000010310.9 | ENST00000652180.1 | GIPR-209 | hsa-miR-5581-3p | chr19 | 45681964 | 45681970 | 7mer-m8 | 45681951 | 45681971 | 147 | -12.87 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000010310.9 | ENST00000590918.6 | GIPR-205 | hsa-miR-589-5p | chr19 | 45683661 | 45683667 | 7mer-m8 | 45683646 | 45683668 | 142 | -17.53 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000010310.9 | ENST00000652180.1 | GIPR-209 | hsa-miR-589-5p | chr19 | 45683661 | 45683667 | 7mer-m8 | 45683646 | 45683668 | 142 | -17.53 |
| ADediting_1596844 | chr1_162342605_+ | ENSG00000010310.9 | ENST00000590918.6 | GIPR-205 | hsa-miR-556-3p | chr19 | 45682428 | 45682434 | 7mer-m8 | 45682414 | 45682435 | 145 | -12.71 |
| ADediting_1596844 | chr1_162342605_+ | ENSG00000010310.9 | ENST00000652180.1 | GIPR-209 | hsa-miR-556-3p | chr19 | 45682428 | 45682434 | 7mer-m8 | 45682414 | 45682435 | 145 | -12.71 |
| ADediting_496066 | chr15_66496985_- | ENSG00000010310.9 | ENST00000590918.6 | GIPR-205 | hsa-miR-4512 | chr19 | 45682280 | 45682286 | 7mer-m8 | 45682261 | 45682287 | 149 | -22.96 |
| ADediting_496066 | chr15_66496985_- | ENSG00000010310.9 | ENST00000652180.1 | GIPR-209 | hsa-miR-4512 | chr19 | 45682280 | 45682286 | 7mer-m8 | 45682261 | 45682287 | 149 | -22.96 |
| Differentially expressed gene-miRNA network |
| Differentially expressed mRNA-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for GIPR |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000652180.1 | protein_coding |  |  |
| ENST00000590918.6 | protein_coding |  |  |
| ENST00000591322.1 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_763147 | ENST00000652180.1 | chr19_45682527_+ | 2247 | -1417.20 | -1416.90 | -1421.40 |
| ADediting_763148 | ENST00000652180.1 | chr19_45682625_+ | 2345 | -1416.90 | -1416.90 | -1421.40 |
| ADediting_763149 | ENST00000652180.1 | chr19_45682630_+ | 2350 | -1416.80 | -1416.90 | -1421.40 |
| ADediting_763150 | ENST00000652180.1 | chr19_45682683_+ | 2403 | -1417.50 | -1416.90 | -1421.40 |
| ADediting_763151 | ENST00000652180.1 | chr19_45682805_+ | 2525 | -1416.90 | -1416.90 | -1421.40 |
| ADediting_763152 | ENST00000652180.1 | chr19_45682817_+ | 2537 | -1418.50 | -1416.90 | -1421.40 |
| ADediting_763147 | ENST00000590918.6 | chr19_45682527_+ | 2115 | -1350.40 | -1350.60 | -1353.80 |
| ADediting_763148 | ENST00000590918.6 | chr19_45682625_+ | 2213 | -1350.60 | -1350.60 | -1353.80 |
| ADediting_763149 | ENST00000590918.6 | chr19_45682630_+ | 2218 | -1350.50 | -1350.60 | -1353.80 |
| ADediting_763150 | ENST00000590918.6 | chr19_45682683_+ | 2271 | -1350.30 | -1350.60 | -1353.80 |
| ADediting_763151 | ENST00000590918.6 | chr19_45682805_+ | 2393 | -1350.60 | -1350.60 | -1353.80 |
| ADediting_763152 | ENST00000590918.6 | chr19_45682817_+ | 2405 | -1352.20 | -1350.60 | -1353.80 |
| ADediting_763073 | ENST00000591322.1 | chr19_45670266_+ | 11 | -196.90 | -196.00 | -203.40 |
| ADediting_763074 | ENST00000591322.1 | chr19_45670267_+ | 12 | -196.10 | -196.00 | -203.40 |
| ADediting_763075 | ENST00000591322.1 | chr19_45670293_+ | 38 | -198.70 | -196.00 | -203.40 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for GIPR |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_763108 | chr19_45678417_+ | 0.117725668643952 | 0.0890346004358348 | 0.821978324911594 | 0.0128305167151112 | 1.04023167194957e-11 | 0.373687523275636 |
| DLPFC | ADediting_763111 | chr19_45678481_+ | 0.459205689449635 | 0.0421897184630399 | 0.993894392157286 | -0.000436385403718231 | 1.12259412284129e-09 | 0.337123950645783 |
| DLPFC | ADediting_763145 | chr19_45681398_+ | 0.423458195333172 | 0.0456223399311378 | 0.808507124430453 | -0.0138198621417869 | 4.4893476748182e-09 | 0.325323103318559 |
| DLPFC | ADediting_763146 | chr19_45681410_+ | 0.0579453001651191 | 0.107813340012537 | 0.825714274398897 | -0.0125568349143214 | 2.01237509734728e-18 | 0.469779925422138 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| AC | 2.98038913873859e-07 | 0.317289975284795 | 6.27559759239453e-06 | 0.281293376239129 | 3.02969727578981e-05 | 0.260546299959272 |
| CER | 0.0128403060904223 | 0.202739678977129 | 1.01013621371124e-06 | 0.386821337613213 | 0.00815914493965441 | 0.21525950096863 |
| TCX | 0.950122973179515 | 0.00515043013023926 | 0.0108381323619416 | -0.207499613277643 | 3.57910879546594e-05 | 0.33068809031342 |
| FP | 0.345267775750253 | 0.071152981596644 | 0.0234207394734212 | 0.169841834435955 | 1.68308080357081e-05 | 0.31644401845511 |
| IFG | 0.298624165939612 | 0.216482716332668 | 0.164492455649823 | 0.286825995277637 | 0.0219677241868392 | 0.455990038178981 |
| PG | 0.187657320852129 | -0.0970328002179811 | 0.126740834313536 | -0.112373609404099 | 2.08083130990559e-07 | 0.369617057323636 |
| STG | 0.655006571996383 | -0.0494631144488301 | 0.26837828600533 | -0.122139643180069 | 1.00689424667589e-09 | 0.60601905733604 |
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Relation with AD stages for GIPR |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 2.80690810115038e-06 | 0.43333462974055 |
| TCX | 0.000248368336889702 | 0.348766264791558 |
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RelatedDrugs for GIPR |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for GIPR |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| GIPR | C0005910 | Body Weight | 1 | CTD_human |
| GIPR | C0007131 | Non-Small Cell Lung Carcinoma | 1 | CTD_human |
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