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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for CCDC28A

check button Gene summary
Gene informationGene symbol

CCDC28A

Gene ID

25901

Gene namecoiled-coil domain containing 28A
SynonymsC6orf80|CCRL1AP
Cytomap

6q24.1

Type of geneprotein-coding
Descriptioncoiled-coil domain-containing protein 28Achemokine C-C motif receptor-like 1 adjacent
Modification date20200321
UniProtAcc

Q8IWP9,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for CCDC28A

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1234517(138788599, +), ADediting_1234518(138788619, +), ADediting_1234519(138788626, +), ADediting_1234520(138788637, +), ADediting_1234521(138788643, +), ADediting_1234522(138788653, +), ADediting_1234523(138788655, +), ADediting_1234524(138788661, +), ADediting_1234525(138788670, +), ADediting_1234526(138788676, +), ADediting_1234527(138788677, +), ADediting_1234528(138788689, +), ADediting_1234529(138788694, +), ADediting_1234530(138788703, +), ADediting_1234531(138788704, +), ADediting_1234532(138788716, +), ADediting_1234533(138789551, +), ADediting_1234534(138789569, +), ADediting_1234535(138789570, +), ADediting_1234536(138789575, +), ADediting_1234537(138789615, +), ADediting_1234538(138789623, +), ADediting_1234539(138789624, +), ADediting_1234540(138789629, +), ADediting_1234541(138789660, +), ADediting_1234542(138789663, +), ADediting_1234543(138789669, +), ADediting_1234544(138789678, +), ADediting_1234545(138789682, +), ADediting_1234546(138789704, +), ADediting_1234547(138789705, +), ADediting_1234548(138789710, +), ADediting_1234549(138789714, +), ADediting_1234550(138789721, +), ADediting_1234551(138789731, +), ADediting_1234552(138789737, +), ADediting_1234553(138789746, +), ADediting_1234554(138789769, +), ADediting_1234555(138789773, +), ADediting_1234556(138790173, +), ADediting_1234557(138790196, +), ADediting_1234558(138790206, +), ADediting_1234559(138790209, +), ADediting_1234560(138790225, +), ADediting_1234561(138790231, +), ADediting_1234562(138790250, +), ADediting_1234563(138790251, +), ADediting_1234564(138790254, +), ADediting_1234565(138790255, +), ADediting_1234566(138790280, +), ADediting_1234567(138790290, +), ADediting_1234568(138790292, +), ADediting_1234569(138790306, +), ADediting_1234570(138790312, +), ADediting_1234571(138790316, +), ADediting_1234572(138790317, +), ADediting_1234573(138790325, +), ADediting_1234574(138790331, +), ADediting_1234575(138790334, +), ADediting_1234576(138790348, +), ADediting_1234577(138790351, +), ADediting_1234578(138790360, +), ADediting_1234579(138790373, +), ADediting_1234580(138790384, +), ADediting_1234581(138790411, +), ADediting_1234582(138790412, +), ADediting_1234583(138790424, +), ADediting_1234584(138790430, +), ADediting_1234585(138791316, +), ADediting_1234586(138791317, +), ADediting_1234587(138791334, +), ADediting_1234588(138792251, +), ADediting_1234589(138792267, +), ADediting_1234590(138792273, +), ADediting_1234591(138792274, +), ADediting_1234592(138792279, +), ADediting_1234593(138792296, +), ADediting_1234594(138792300, +), ADediting_1234595(138792304, +), ADediting_1234596(138792319, +), ADediting_1234597(138792327, +), ADediting_1234598(138792328, +), ADediting_1234599(138792364, +), ADediting_1234600(138792380, +), ADediting_1234601(138792393, +), ADediting_1234602(138792418, +), ADediting_1234603(138792424, +), ADediting_1234604(138792442, +), ADediting_1234605(138792447, +), ADediting_1234606(138792455, +), ADediting_1234607(138792456, +), ADediting_1234608(138792461, +), ADediting_1234609(138792463, +), ADediting_1234610(138792467, +), ADediting_1234611(138792468, +), ADediting_1234612(138792479, +), ADediting_1234613(138792492, +), ADediting_1234614(138792505, +), ADediting_1234615(138792517, +), ADediting_1234616(138792523, +), ADediting_1582629(138788199, +), ADediting_1582630(138788662, +), ADediting_1582631(138789586, +), ADediting_1582632(138789618, +), ADediting_1582633(138789639, +), ADediting_1582634(138789664, +), ADediting_1582635(138789665, +), ADediting_1582636(138789666, +), ADediting_1582637(138789667, +), ADediting_1582638(138789674, +), ADediting_1582639(138789675, +), ADediting_1582640(138789745, +), ADediting_1582641(138790203, +), ADediting_1582642(138790221, +), ADediting_1582643(138791302, +), ADediting_1582644(138791344, +), ADediting_1582645(138792282, +), ADediting_1582646(138792290, +), ADediting_1582647(138792496, +), ADediting_1659967(138789770, +), ADediting_1659968(138790230, +),

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RNA editing positional annotations for CCDC28A using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1234517chr6_138788599_+intronic
ADediting_1234518chr6_138788619_+intronic
ADediting_1234519chr6_138788626_+intronic
ADediting_1234520chr6_138788637_+intronic
ADediting_1234521chr6_138788643_+intronic
ADediting_1234522chr6_138788653_+intronic
ADediting_1234523chr6_138788655_+intronic
ADediting_1234524chr6_138788661_+intronic
ADediting_1234525chr6_138788670_+intronic
ADediting_1234526chr6_138788676_+intronic
ADediting_1234527chr6_138788677_+intronic
ADediting_1234528chr6_138788689_+intronic
ADediting_1234529chr6_138788694_+intronic
ADediting_1234530chr6_138788703_+intronic
ADediting_1234531chr6_138788704_+intronic
ADediting_1234532chr6_138788716_+intronic
ADediting_1234533chr6_138789551_+intronic
ADediting_1234534chr6_138789569_+intronic
ADediting_1234535chr6_138789570_+intronic
ADediting_1234536chr6_138789575_+intronic
ADediting_1234537chr6_138789615_+intronic
ADediting_1234538chr6_138789623_+intronic
ADediting_1234539chr6_138789624_+intronic
ADediting_1234540chr6_138789629_+intronic
ADediting_1234541chr6_138789660_+intronic
ADediting_1234542chr6_138789663_+intronic
ADediting_1234543chr6_138789669_+intronic
ADediting_1234544chr6_138789678_+intronic
ADediting_1234545chr6_138789682_+intronic
ADediting_1234546chr6_138789704_+intronic
ADediting_1234547chr6_138789705_+intronic
ADediting_1234548chr6_138789710_+intronic
ADediting_1234549chr6_138789714_+intronic
ADediting_1234550chr6_138789721_+intronic
ADediting_1234551chr6_138789731_+intronic
ADediting_1234552chr6_138789737_+intronic
ADediting_1234553chr6_138789746_+intronic
ADediting_1234554chr6_138789769_+intronic
ADediting_1234555chr6_138789773_+intronic
ADediting_1234556chr6_138790173_+intronic
ADediting_1234557chr6_138790196_+intronic
ADediting_1234558chr6_138790206_+intronic
ADediting_1234559chr6_138790209_+intronic
ADediting_1234560chr6_138790225_+intronic
ADediting_1234561chr6_138790231_+intronic
ADediting_1234562chr6_138790250_+intronic
ADediting_1234563chr6_138790251_+intronic
ADediting_1234564chr6_138790254_+intronic
ADediting_1234565chr6_138790255_+intronic
ADediting_1234566chr6_138790280_+intronic
ADediting_1234567chr6_138790290_+intronic
ADediting_1234568chr6_138790292_+intronic
ADediting_1234569chr6_138790306_+intronic
ADediting_1234570chr6_138790312_+intronic
ADediting_1234571chr6_138790316_+intronic
ADediting_1234572chr6_138790317_+intronic
ADediting_1234573chr6_138790325_+intronic
ADediting_1234574chr6_138790331_+intronic
ADediting_1234575chr6_138790334_+intronic
ADediting_1234576chr6_138790348_+intronic
ADediting_1234577chr6_138790351_+intronic
ADediting_1234578chr6_138790360_+intronic
ADediting_1234579chr6_138790373_+intronic
ADediting_1234580chr6_138790384_+intronic
ADediting_1234581chr6_138790411_+intronic
ADediting_1234582chr6_138790412_+intronic
ADediting_1234583chr6_138790424_+intronic
ADediting_1234584chr6_138790430_+intronic
ADediting_1234585chr6_138791316_+intronic
ADediting_1234586chr6_138791317_+intronic
ADediting_1234587chr6_138791334_+intronic
ADediting_1234588chr6_138792251_+intronic
ADediting_1234589chr6_138792267_+intronic
ADediting_1234590chr6_138792273_+intronic
ADediting_1234591chr6_138792274_+intronic
ADediting_1234592chr6_138792279_+intronic
ADediting_1234593chr6_138792296_+intronic
ADediting_1234594chr6_138792300_+intronic
ADediting_1234595chr6_138792304_+intronic
ADediting_1234596chr6_138792319_+intronic
ADediting_1234597chr6_138792327_+intronic
ADediting_1234598chr6_138792328_+intronic
ADediting_1234599chr6_138792364_+intronic
ADediting_1234600chr6_138792380_+intronic
ADediting_1234601chr6_138792393_+intronic
ADediting_1234602chr6_138792418_+intronic
ADediting_1234603chr6_138792424_+intronic
ADediting_1234604chr6_138792442_+intronic
ADediting_1234605chr6_138792447_+intronic
ADediting_1234606chr6_138792455_+intronic
ADediting_1234607chr6_138792456_+intronic
ADediting_1234608chr6_138792461_+intronic
ADediting_1234609chr6_138792463_+intronic
ADediting_1234610chr6_138792467_+intronic
ADediting_1234611chr6_138792468_+intronic
ADediting_1234612chr6_138792479_+intronic
ADediting_1234613chr6_138792492_+intronic
ADediting_1234614chr6_138792505_+intronic
ADediting_1234615chr6_138792517_+intronic
ADediting_1234616chr6_138792523_+intronic
ADediting_1582629chr6_138788199_+intronic
ADediting_1582630chr6_138788662_+intronic
ADediting_1582631chr6_138789586_+intronic
ADediting_1582632chr6_138789618_+intronic
ADediting_1582633chr6_138789639_+intronic
ADediting_1582634chr6_138789664_+intronic
ADediting_1582635chr6_138789665_+intronic
ADediting_1582636chr6_138789666_+intronic
ADediting_1582637chr6_138789667_+intronic
ADediting_1582638chr6_138789674_+intronic
ADediting_1582639chr6_138789675_+intronic
ADediting_1582640chr6_138789745_+intronic
ADediting_1582641chr6_138790203_+intronic
ADediting_1582642chr6_138790221_+intronic
ADediting_1582643chr6_138791302_+intronic
ADediting_1582644chr6_138791344_+intronic
ADediting_1582645chr6_138792282_+intronic
ADediting_1582646chr6_138792290_+intronic
ADediting_1582647chr6_138792496_+intronic
ADediting_1659967chr6_138789770_+intronic
ADediting_1659968chr6_138790230_+intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1234517chr6_138788599_+SINEAluName=AluJb
ADediting_1234518chr6_138788619_+SINEAluName=AluJb
ADediting_1234519chr6_138788626_+SINEAluName=AluJb
ADediting_1234520chr6_138788637_+SINEAluName=AluJb
ADediting_1234521chr6_138788643_+SINEAluName=AluJb
ADediting_1234522chr6_138788653_+SINEAluName=AluJb
ADediting_1234523chr6_138788655_+SINEAluName=AluJb
ADediting_1234524chr6_138788661_+SINEAluName=AluJb
ADediting_1234525chr6_138788670_+SINEAluName=AluJb
ADediting_1234526chr6_138788676_+SINEAluName=AluJb
ADediting_1234527chr6_138788677_+SINEAluName=AluJb
ADediting_1234528chr6_138788689_+SINEAluName=AluJb
ADediting_1234529chr6_138788694_+SINEAluName=AluJb
ADediting_1234530chr6_138788703_+SINEAluName=AluJb
ADediting_1234531chr6_138788704_+SINEAluName=AluJb
ADediting_1234532chr6_138788716_+SINEAluName=AluJb
ADediting_1234533chr6_138789551_+SINEAluName=AluSq2
ADediting_1234534chr6_138789569_+SINEAluName=AluSq2
ADediting_1234535chr6_138789570_+SINEAluName=AluSq2
ADediting_1234536chr6_138789575_+SINEAluName=AluSq2
ADediting_1234537chr6_138789615_+SINEAluName=AluSq2
ADediting_1234538chr6_138789623_+SINEAluName=AluSq2
ADediting_1234539chr6_138789624_+SINEAluName=AluSq2
ADediting_1234540chr6_138789629_+SINEAluName=AluSq2
ADediting_1234541chr6_138789660_+SINEAluName=AluSq2
ADediting_1234542chr6_138789663_+SINEAluName=AluSq2
ADediting_1234543chr6_138789669_+SINEAluName=AluSq2
ADediting_1234544chr6_138789678_+SINEAluName=AluSq2
ADediting_1234545chr6_138789682_+SINEAluName=AluSq2
ADediting_1234546chr6_138789704_+SINEAluName=AluSq2
ADediting_1234547chr6_138789705_+SINEAluName=AluSq2
ADediting_1234548chr6_138789710_+SINEAluName=AluSq2
ADediting_1234549chr6_138789714_+SINEAluName=AluSq2
ADediting_1234550chr6_138789721_+SINEAluName=AluSq2
ADediting_1234551chr6_138789731_+SINEAluName=AluSq2
ADediting_1234552chr6_138789737_+SINEAluName=AluSq2
ADediting_1234553chr6_138789746_+SINEAluName=AluSq2
ADediting_1234554chr6_138789769_+SINEAluName=AluSq2
ADediting_1234555chr6_138789773_+SINEAluName=AluSq2
ADediting_1234556chr6_138790173_+SINEAluName=AluSx1
ADediting_1234557chr6_138790196_+SINEAluName=AluSx1
ADediting_1234558chr6_138790206_+SINEAluName=AluSx1
ADediting_1234559chr6_138790209_+SINEAluName=AluSx1
ADediting_1234560chr6_138790225_+SINEAluName=AluSx1
ADediting_1234561chr6_138790231_+SINEAluName=AluSx1
ADediting_1234562chr6_138790250_+SINEAluName=AluSx1
ADediting_1234563chr6_138790251_+SINEAluName=AluSx1
ADediting_1234564chr6_138790254_+SINEAluName=AluSx1
ADediting_1234565chr6_138790255_+SINEAluName=AluSx1
ADediting_1234566chr6_138790280_+SINEAluName=AluSx1
ADediting_1234567chr6_138790290_+SINEAluName=AluSx1
ADediting_1234568chr6_138790292_+SINEAluName=AluSx1
ADediting_1234569chr6_138790306_+SINEAluName=AluSx1
ADediting_1234570chr6_138790312_+SINEAluName=AluSx1
ADediting_1234571chr6_138790316_+SINEAluName=AluSx1
ADediting_1234572chr6_138790317_+SINEAluName=AluSx1
ADediting_1234573chr6_138790325_+SINEAluName=AluSx1
ADediting_1234574chr6_138790331_+SINEAluName=AluSx1
ADediting_1234575chr6_138790334_+SINEAluName=AluSx1
ADediting_1234576chr6_138790348_+SINEAluName=AluSx1
ADediting_1234577chr6_138790351_+SINEAluName=AluSx1
ADediting_1234578chr6_138790360_+SINEAluName=AluSx1
ADediting_1234579chr6_138790373_+SINEAluName=AluSx1
ADediting_1234580chr6_138790384_+SINEAluName=AluSx1
ADediting_1234581chr6_138790411_+SINEAluName=AluSx1
ADediting_1234582chr6_138790412_+SINEAluName=AluSx1
ADediting_1234583chr6_138790424_+SINEAluName=AluSx1
ADediting_1234584chr6_138790430_+SINEAluName=AluSx1
ADediting_1234585chr6_138791316_+SINEAluName=AluJo
ADediting_1234586chr6_138791317_+SINEAluName=AluJo
ADediting_1234587chr6_138791334_+SINEAluName=AluJo
ADediting_1234588chr6_138792251_+SINEAluName=AluJr
ADediting_1234589chr6_138792267_+SINEAluName=AluJr
ADediting_1234590chr6_138792273_+SINEAluName=AluJr
ADediting_1234591chr6_138792274_+SINEAluName=AluJr
ADediting_1234592chr6_138792279_+SINEAluName=AluJr
ADediting_1234593chr6_138792296_+SINEAluName=AluJr
ADediting_1234594chr6_138792300_+SINEAluName=AluJr
ADediting_1234595chr6_138792304_+SINEAluName=AluJr
ADediting_1234596chr6_138792319_+SINEAluName=AluJr
ADediting_1234597chr6_138792327_+SINEAluName=AluJr
ADediting_1234598chr6_138792328_+SINEAluName=AluJr
ADediting_1234599chr6_138792364_+SINEAluName=AluJr
ADediting_1234600chr6_138792380_+SINEAluName=AluJr
ADediting_1234601chr6_138792393_+SINEAluName=AluJr
ADediting_1234602chr6_138792418_+SINEAluName=AluJr
ADediting_1234603chr6_138792424_+SINEAluName=AluJr
ADediting_1234604chr6_138792442_+SINEAluName=AluJr
ADediting_1234605chr6_138792447_+SINEAluName=AluJr
ADediting_1234606chr6_138792455_+SINEAluName=AluJr
ADediting_1234607chr6_138792456_+SINEAluName=AluJr
ADediting_1234608chr6_138792461_+SINEAluName=AluJr
ADediting_1234609chr6_138792463_+SINEAluName=AluJr
ADediting_1234610chr6_138792467_+SINEAluName=AluJr
ADediting_1234611chr6_138792468_+SINEAluName=AluJr
ADediting_1234612chr6_138792479_+SINEAluName=AluJr
ADediting_1234613chr6_138792492_+SINEAluName=AluJr
ADediting_1234614chr6_138792505_+SINEAluName=AluJr
ADediting_1234615chr6_138792517_+SINEAluName=AluJr
ADediting_1234616chr6_138792523_+SINEAluName=AluJr
ADediting_1582629chr6_138788199_+SINEAluName=AluJo
ADediting_1582630chr6_138788662_+SINEAluName=AluJb
ADediting_1582631chr6_138789586_+SINEAluName=AluSq2
ADediting_1582632chr6_138789618_+SINEAluName=AluSq2
ADediting_1582633chr6_138789639_+SINEAluName=AluSq2
ADediting_1582634chr6_138789664_+SINEAluName=AluSq2
ADediting_1582635chr6_138789665_+SINEAluName=AluSq2
ADediting_1582636chr6_138789666_+SINEAluName=AluSq2
ADediting_1582637chr6_138789667_+SINEAluName=AluSq2
ADediting_1582638chr6_138789674_+SINEAluName=AluSq2
ADediting_1582639chr6_138789675_+SINEAluName=AluSq2
ADediting_1582640chr6_138789745_+SINEAluName=AluSq2
ADediting_1582641chr6_138790203_+SINEAluName=AluSx1
ADediting_1582642chr6_138790221_+SINEAluName=AluSx1
ADediting_1582643chr6_138791302_+SINEAluName=AluJo
ADediting_1582644chr6_138791344_+SINEAluName=AluJo
ADediting_1582645chr6_138792282_+SINEAluName=AluJr
ADediting_1582646chr6_138792290_+SINEAluName=AluJr
ADediting_1582647chr6_138792496_+SINEAluName=AluJr
ADediting_1659967chr6_138789770_+SINEAluName=AluSq2
ADediting_1659968chr6_138790230_+SINEAluName=AluSx1

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RNA A-to-I editing events in the alternative splicing sites for CCDC28A

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CCDC28A

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for CCDC28A

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for CCDC28A


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_843620chr2_207754818_+ENSG00000024862.17ENST00000332797.10CCDC28A-201hsa-miR-4775chr61387932591387932657mer-1a138793243138793265155-17.68
ADediting_843620chr2_207754818_+ENSG00000024862.17ENST00000611852.4CCDC28A-202hsa-miR-4775chr61387932591387932657mer-1a138793243138793265155-17.68
ADediting_843620chr2_207754818_+ENSG00000024862.17ENST00000617445.4CCDC28A-203hsa-miR-4775chr61387932591387932657mer-1a138793243138793265155-17.68

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CCDC28A

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for CCDC28A

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_1234522chr6_138788653_+5.13871112964902e-050.2278684520072170.003950926757438120.1632496292003125.70195712771952e-090.323235449906766
CERADediting_1234529chr6_138788694_+0.0004704883070406930.2820696256775935.63726689556054e-050.3227019455394280.04736006790978110.162199684482942
DLPFCADediting_1234549chr6_138789714_+0.0001564906526885360.213109286717330.1717622653932950.07781219017172055.06108828121972e-150.424927191189758
DLPFCADediting_1234550chr6_138789721_+0.004686430277510910.1602185243354240.1721294133690120.07774578907951391.07871727622266e-080.317589775019211
CERADediting_1234552chr6_138789737_+0.003010686882959620.2406681587727227.42509390547697e-050.3177483879229860.4573393764578550.0611395471842588
DLPFCADediting_1234554chr6_138789769_+9.4908818974061e-110.3570001583689531.04478777869732e-050.2474360135445557.48210371291985e-090.32084368141546
CERADediting_1234554chr6_138789769_+0.0005903414417067020.2773450777356990.0001584975688285610.3036460481561370.3364221716218140.0790246865809707
DLPFCADediting_1234555chr6_138789773_+8.28037311086139e-090.3199459171921536.57128254747529e-050.2246928425311127.4548379925914e-080.299712941247808
DLPFCADediting_1234558chr6_138790206_+1.13555474168671e-060.272263095051187.02891262346025e-050.2238155286291668.27405331286924e-090.319952689918351
CERADediting_1234558chr6_138790206_+9.994681860944e-050.3123053681326760.0002867202272439370.2921023465084650.7068051865641280.0309642037830406
DLPFCADediting_1234559chr6_138790209_+1.75796846557349e-060.2675686266010560.0001333631784311020.2152907348517461.26384183617746e-090.336134288926277
CERADediting_1234559chr6_138790209_+6.11995378999126e-060.3598035632233081.13107543181432e-050.3500027581255160.1379193823649010.121701455352868
CERADediting_1234562chr6_138790250_+0.0004458393021326920.2831778912242892.48951521447904e-070.4062769587988530.830153394940755-0.0176606199917112
CERADediting_1234563chr6_138790251_+0.006852789733294660.2199040986024450.0001459352482710240.3052166438263180.6198971601564810.0408225230770144
CERADediting_1234565chr6_138790255_+0.0001552534575177220.3040402176459672.83370859116838e-070.4045291990296210.1832107444181180.109258673474246
DLPFCADediting_1234566chr6_138790280_+6.95617932871296e-050.2239513023291970.03540150476443220.1195383191767162.40645236577598e-160.443169827965752
CERADediting_1234566chr6_138790280_+0.004441028069478520.231074639401511.42238956994489e-050.3462607651987910.1936923199706510.106712198841318
DLPFCADediting_1234567chr6_138790290_+0.0003503219350378510.2017653726393470.04231740468767350.1153987854908461.10412865507755e-090.337262172048668
CERADediting_1234567chr6_138790290_+0.01686279629939320.1948728145848740.0001491214150903250.3048067085089040.2467039536495450.0951636048929186
DLPFCADediting_1234570chr6_138790312_+0.007862453190182190.1507053957271850.2133954487430280.07086792559392315.10170560789167e-090.324208637961635
DLPFCADediting_1234580chr6_138790384_+7.43241517173086e-080.2997417520522772.31298964903566e-080.3106774018594920.0002692247274190750.205539032656431
DLPFCADediting_1234583chr6_138790424_+5.77320472346521e-100.3426131671242612.3750998047688e-100.3497817704580430.001304220007648770.181812778283481
CERADediting_1234583chr6_138790424_+0.02142281115315530.1877281321982213.20713786536402e-050.3325843670373340.07192938383746590.147363350836254
DLPFCADediting_1234608chr6_138792461_+4.44411557530118e-070.2820534123631771.7337793991746e-100.3522791443973760.01466640591363910.138502672450589
DLPFCADediting_1234609chr6_138792463_+6.12767698756541e-080.3015814645610766.89985148014588e-100.341152120067820.02339881159380780.128732858278767
DLPFCADediting_1234612chr6_138792479_+1.35007933766034e-060.2704149056365313.48157105074499e-080.3068971231835120.04228495671470590.115416827171489

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.31780084411771e-500.7190635482100548.47865784419909e-720.8049518681263650.3377305282342590.0546281928080707
AC2.7824450785765e-720.8538621431174961.29619302108441e-480.7615341924561585.4898515828926e-110.399322669344239
PCC1.49589665153915e-310.7179036643641961.39367625085072e-320.7261879431852070.04095561772251860.148052930796814
TCX1.38797965663438e-210.6786765598254466.10459821729106e-250.7167630879132760.0420260774228177-0.166248739395059
FP1.60900243902742e-170.5819430700325963.1414609910263e-250.6771740302449510.663242939859134-0.0328603154270501
IFG0.001291829482078230.6070547670370730.004475849839385240.5490654310061320.22727691565612-0.250430551183551
PG2.08367798207734e-560.8628195114597565.38189555390268e-320.7280658545079820.333127154793485-0.0713555739630198
STG2.14788152118845e-150.733349853084514.57580010254221e-190.789475442770260.268988144005692-0.121985302741147

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Relation with AD stages for CCDC28A

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
TCXADediting_1234517chr6_138788599_+0.0001623900851883360.358310702041407

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.

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RelatedDrugs for CCDC28A

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for CCDC28A

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource