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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

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The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

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Relation with AD stages

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Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for INTS7

check button Gene summary
Gene informationGene symbol

INTS7

Gene ID

25896

Gene nameintegrator complex subunit 7
SynonymsC1orf73|INT7
Cytomap

1q32.3

Type of geneprotein-coding
Descriptionintegrator complex subunit 7
Modification date20200313
UniProtAcc

Q9NVH2,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
INTS7

GO:0016180

snRNA processing

16239144

INTS7

GO:0071479

cellular response to ionizing radiation

21659603


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RNA A-to-I events for INTS7

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_63858(211941454, -), ADediting_63859(211941486, -), ADediting_63860(211941490, -), ADediting_63861(211941496, -), ADediting_63862(211941506, -), ADediting_63863(211941514, -), ADediting_63864(211941522, -), ADediting_63865(211941540, -), ADediting_63866(211941554, -), ADediting_63867(211941560, -), ADediting_63868(211941621, -), ADediting_63869(211948832, -), ADediting_63870(211948934, -), ADediting_63871(211957287, -), ADediting_63872(211969028, -), ADediting_63873(211969095, -), ADediting_63874(211969100, -), ADediting_63875(211969163, -), ADediting_63876(211969173, -), ADediting_63877(211969223, -), ADediting_63878(211969226, -), ADediting_63879(211969238, -), ADediting_63880(211969658, -), ADediting_63881(211969659, -), ADediting_63882(211969716, -), ADediting_63883(211969791, -), ADediting_63884(211969867, -), ADediting_63885(211969923, -), ADediting_63886(211969924, -), ADediting_63887(211969947, -), ADediting_63888(211969964, -), ADediting_63889(211969991, -), ADediting_63890(211969997, -), ADediting_63891(211970017, -), ADediting_63892(211970057, -), ADediting_63893(211971744, -), ADediting_63894(211971807, -), ADediting_63895(211971808, -), ADediting_63896(211971833, -), ADediting_1517367(211941401, -), ADediting_1517368(211941555, -), ADediting_1517369(211941627, -), ADediting_1598911(211960933, -), ADediting_1598912(211960963, -),

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RNA editing positional annotations for INTS7 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_63858chr1_211941454_-UTR3
ADediting_63859chr1_211941486_-UTR3
ADediting_63860chr1_211941490_-UTR3
ADediting_63861chr1_211941496_-UTR3
ADediting_63862chr1_211941506_-UTR3
ADediting_63863chr1_211941514_-UTR3
ADediting_63864chr1_211941522_-UTR3
ADediting_63865chr1_211941540_-UTR3
ADediting_63866chr1_211941554_-UTR3
ADediting_63867chr1_211941560_-UTR3
ADediting_63868chr1_211941621_-UTR3
ADediting_63869chr1_211948832_-intronic
ADediting_63870chr1_211948934_-intronic
ADediting_63871chr1_211957287_-intronic
ADediting_63872chr1_211969028_-intronic
ADediting_63873chr1_211969095_-intronic
ADediting_63874chr1_211969100_-intronic
ADediting_63875chr1_211969163_-intronic
ADediting_63876chr1_211969173_-intronic
ADediting_63877chr1_211969223_-intronic
ADediting_63878chr1_211969226_-intronic
ADediting_63879chr1_211969238_-intronic
ADediting_63880chr1_211969658_-intronic
ADediting_63881chr1_211969659_-intronic
ADediting_63882chr1_211969716_-intronic
ADediting_63883chr1_211969791_-intronic
ADediting_63884chr1_211969867_-intronic
ADediting_63885chr1_211969923_-intronic
ADediting_63886chr1_211969924_-intronic
ADediting_63887chr1_211969947_-intronic
ADediting_63888chr1_211969964_-intronic
ADediting_63889chr1_211969991_-intronic
ADediting_63890chr1_211969997_-intronic
ADediting_63891chr1_211970017_-intronic
ADediting_63892chr1_211970057_-intronic
ADediting_63893chr1_211971744_-intronic
ADediting_63894chr1_211971807_-intronic
ADediting_63895chr1_211971808_-intronic
ADediting_63896chr1_211971833_-intronic
ADediting_1517367chr1_211941401_-UTR3
ADediting_1517368chr1_211941555_-UTR3
ADediting_1517369chr1_211941627_-UTR3
ADediting_1598911chr1_211960933_-intronic
ADediting_1598912chr1_211960963_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_63858chr1_211941454_-SINEAluName=AluY
ADediting_63859chr1_211941486_-SINEAluName=AluY
ADediting_63860chr1_211941490_-SINEAluName=AluY
ADediting_63861chr1_211941496_-SINEAluName=AluY
ADediting_63862chr1_211941506_-SINEAluName=AluY
ADediting_63863chr1_211941514_-SINEAluName=AluY
ADediting_63864chr1_211941522_-SINEAluName=AluY
ADediting_63865chr1_211941540_-SINEAluName=AluY
ADediting_63866chr1_211941554_-SINEAluName=AluY
ADediting_63867chr1_211941560_-SINEAluName=AluY
ADediting_63868chr1_211941621_-SINEAluName=AluY
ADediting_63869chr1_211948832_-SINEAluName=AluSg
ADediting_63870chr1_211948934_-SINEAluName=AluSg
ADediting_63871chr1_211957287_-SINEAluName=AluSx
ADediting_63872chr1_211969028_-SINEAluName=AluY
ADediting_63873chr1_211969095_-SINEAluName=AluY
ADediting_63874chr1_211969100_-SINEAluName=AluY
ADediting_63875chr1_211969163_-SINEAluName=AluY
ADediting_63876chr1_211969173_-SINEAluName=AluY
ADediting_63877chr1_211969223_-SINEAluName=AluY
ADediting_63878chr1_211969226_-SINEAluName=AluY
ADediting_63879chr1_211969238_-SINEAluName=AluY
ADediting_63880chr1_211969658_-SINEAluName=AluJr
ADediting_63881chr1_211969659_-SINEAluName=AluJr
ADediting_63882chr1_211969716_-SINEAluName=AluJr
ADediting_63883chr1_211969791_-SINEAluName=AluY
ADediting_63884chr1_211969867_-SINEAluName=AluY
ADediting_63885chr1_211969923_-SINEAluName=AluY
ADediting_63886chr1_211969924_-SINEAluName=AluY
ADediting_63887chr1_211969947_-SINEAluName=AluY
ADediting_63888chr1_211969964_-SINEAluName=AluY
ADediting_63889chr1_211969991_-SINEAluName=AluY
ADediting_63890chr1_211969997_-SINEAluName=AluY
ADediting_63891chr1_211970017_-SINEAluName=AluJr
ADediting_63892chr1_211970057_-SINEAluName=AluJr
ADediting_63893chr1_211971744_-SINEAluName=AluSq2
ADediting_63894chr1_211971807_-SINEAluName=AluSq2
ADediting_63895chr1_211971808_-SINEAluName=AluSq2
ADediting_63896chr1_211971833_-SINEAluName=AluSq2
ADediting_1517367chr1_211941401_-SINEAluName=AluY
ADediting_1517368chr1_211941555_-SINEAluName=AluY
ADediting_1517369chr1_211941627_-SINEAluName=AluY
ADediting_1598911chr1_211960933_-SINEAluName=AluSz
ADediting_1598912chr1_211960963_-SINEAluName=AluSz

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RNA A-to-I editing events in the alternative splicing sites for INTS7

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for INTS7

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot
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boxplot
boxplot
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for INTS7

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for INTS7

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1517367chr1_211941401_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-1181chr12119414012119414077mer-m8211941400211941420147-23.33
ADediting_1517367chr1_211941401_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-1181chr12119414012119414077mer-m8211941400211941420147-23.33
ADediting_1517367chr1_211941401_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-1181chr12119414012119414077mer-m8211941400211941420147-23.33
ADediting_1517368chr1_211941555_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-1304-3pchr12119415542119415618mer-1a211941554211941578152-21.72
ADediting_1517368chr1_211941555_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-1304-3pchr12119415542119415618mer-1a211941554211941578152-21.72
ADediting_1517368chr1_211941555_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-1304-3pchr12119415542119415618mer-1a211941554211941578152-21.72
ADediting_1517368chr1_211941555_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-1304-3pchr12119415542119415618mer-1a211941554211941578152-21.72
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-513a-5pchr12119416262119416327mer-m8211941625211941642140-13.8
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-638chr12119416212119416277mer-1a211941621211941644161-38.31
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-513a-5pchr12119416262119416327mer-m8211941625211941642140-13.8
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-638chr12119416212119416277mer-1a211941621211941644161-38.31
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-513a-5pchr12119416262119416327mer-m8211941625211941642140-13.8
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-638chr12119416212119416277mer-1a211941621211941644161-38.31
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-513a-5pchr12119416262119416327mer-m8211941625211941642140-13.8
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-638chr12119416212119416277mer-1a211941621211941644161-38.31
ADediting_63858chr1_211941454_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-3155achr12119414502119414567mer-m8211941449211941468142-19.16
ADediting_63858chr1_211941454_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-3155bchr12119414502119414567mer-m8211941449211941465142-19.16
ADediting_63858chr1_211941454_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-342-3pchr12119414542119414607mer-m8211941453211941475140-15.26
ADediting_63858chr1_211941454_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-4284chr12119414522119414587mer-m8211941451211941468156-21.36
ADediting_63858chr1_211941454_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-484chr12119414502119414567mer-m8211941449211941470155-25.4
ADediting_63858chr1_211941454_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-3155achr12119414502119414567mer-m8211941449211941468142-19.16
ADediting_63858chr1_211941454_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-3155bchr12119414502119414567mer-m8211941449211941465142-19.16
ADediting_63858chr1_211941454_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-342-3pchr12119414542119414607mer-m8211941453211941475140-15.26
ADediting_63858chr1_211941454_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-4284chr12119414522119414587mer-m8211941451211941468156-21.36
ADediting_63858chr1_211941454_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-484chr12119414502119414567mer-m8211941449211941470155-25.4
ADediting_63858chr1_211941454_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-3155achr12119414502119414567mer-m8211941449211941468142-19.16
ADediting_63858chr1_211941454_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-3155bchr12119414502119414567mer-m8211941449211941465142-19.16
ADediting_63858chr1_211941454_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-342-3pchr12119414542119414607mer-m8211941453211941475140-15.26
ADediting_63858chr1_211941454_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-4284chr12119414522119414587mer-m8211941451211941468156-21.36
ADediting_63858chr1_211941454_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-484chr12119414502119414567mer-m8211941449211941470155-25.4
ADediting_63859chr1_211941486_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-1207-3pchr12119414862119414927mer-m8211941485211941503145-13.53
ADediting_63859chr1_211941486_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-646chr12119414842119414907mer-m8211941483211941502148-22.3
ADediting_63859chr1_211941486_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-1207-3pchr12119414862119414927mer-m8211941485211941503145-13.53
ADediting_63859chr1_211941486_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-646chr12119414842119414907mer-m8211941483211941502148-22.3
ADediting_63859chr1_211941486_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-1207-3pchr12119414862119414927mer-m8211941485211941503145-13.53
ADediting_63859chr1_211941486_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-646chr12119414842119414907mer-m8211941483211941502148-22.3
ADediting_63861chr1_211941496_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-140-3pchr12119414942119415007mer-m8211941493211941513147-22.25
ADediting_63861chr1_211941496_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-140-3pchr12119414942119415007mer-m8211941493211941513147-22.25
ADediting_63861chr1_211941496_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-140-3pchr12119414942119415007mer-m8211941493211941513147-22.25
ADediting_63862chr1_211941506_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-4258chr12119415042119415107mer-m8211941503211941520154-29.36
ADediting_63862chr1_211941506_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-4707-3pchr12119415032119415097mer-m8211941502211941524155-26.49
ADediting_63862chr1_211941506_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-4258chr12119415042119415107mer-m8211941503211941520154-29.36
ADediting_63862chr1_211941506_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-4707-3pchr12119415032119415097mer-m8211941502211941524155-26.49
ADediting_63862chr1_211941506_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-4258chr12119415042119415107mer-m8211941503211941520154-29.36
ADediting_63862chr1_211941506_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-4707-3pchr12119415032119415097mer-m8211941502211941524155-26.49
ADediting_63864chr1_211941522_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-548schr12119415172119415248mer-1a211941517211941538143-10.44
ADediting_63864chr1_211941522_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-548schr12119415172119415248mer-1a211941517211941538143-10.44
ADediting_63864chr1_211941522_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-548schr12119415172119415248mer-1a211941517211941538143-10.44
ADediting_63865chr1_211941540_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-194-3pchr12119415392119415457mer-1a211941539211941559142-17.61
ADediting_63865chr1_211941540_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-30a-3pchr12119415362119415438mer-1a211941536211941560150-12.23
ADediting_63865chr1_211941540_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-30d-3pchr12119415362119415438mer-1a211941536211941562150-16
ADediting_63865chr1_211941540_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-30e-3pchr12119415362119415438mer-1a211941536211941560150-14.38
ADediting_63865chr1_211941540_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-194-3pchr12119415392119415457mer-1a211941539211941559142-17.61
ADediting_63865chr1_211941540_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-30a-3pchr12119415362119415438mer-1a211941536211941560150-12.23
ADediting_63865chr1_211941540_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-30d-3pchr12119415362119415438mer-1a211941536211941562150-16
ADediting_63865chr1_211941540_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-30e-3pchr12119415362119415438mer-1a211941536211941560150-14.38
ADediting_63865chr1_211941540_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-194-3pchr12119415392119415457mer-1a211941539211941559142-17.61
ADediting_63865chr1_211941540_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-30a-3pchr12119415362119415438mer-1a211941536211941560150-12.23
ADediting_63865chr1_211941540_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-30d-3pchr12119415362119415438mer-1a211941536211941562150-16
ADediting_63865chr1_211941540_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-30e-3pchr12119415362119415438mer-1a211941536211941560150-14.38
ADediting_63865chr1_211941540_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-194-3pchr12119415392119415457mer-1a211941539211941559142-17.61
ADediting_63865chr1_211941540_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-30a-3pchr12119415362119415438mer-1a211941536211941560150-12.23
ADediting_63865chr1_211941540_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-30d-3pchr12119415362119415438mer-1a211941536211941562150-16
ADediting_63865chr1_211941540_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-30e-3pchr12119415362119415438mer-1a211941536211941560150-14.38
ADediting_63866chr1_211941554_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-4508chr12119415492119415557mer-m8211941548211941564140-21.16
ADediting_63866chr1_211941554_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-6837-3pchr12119415542119415607mer-m8211941553211941575155-18.62
ADediting_63866chr1_211941554_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-4508chr12119415492119415557mer-m8211941548211941564140-21.16
ADediting_63866chr1_211941554_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-6837-3pchr12119415542119415607mer-m8211941553211941575155-18.62
ADediting_63866chr1_211941554_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-4508chr12119415492119415557mer-m8211941548211941564140-21.16
ADediting_63866chr1_211941554_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-6837-3pchr12119415542119415607mer-m8211941553211941575155-18.62
ADediting_63866chr1_211941554_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-4508chr12119415492119415557mer-m8211941548211941564140-21.16
ADediting_63866chr1_211941554_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-6837-3pchr12119415542119415607mer-m8211941553211941575155-18.62
ADediting_63868chr1_211941621_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-371a-3pchr12119416162119416227mer-m8211941615211941637145-17.36
ADediting_63868chr1_211941621_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-371a-3pchr12119416162119416227mer-m8211941615211941637145-17.36
ADediting_63868chr1_211941621_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-371a-3pchr12119416162119416227mer-m8211941615211941637145-17.36
ADediting_63868chr1_211941621_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-371a-3pchr12119416162119416227mer-m8211941615211941637145-17.36

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1517368chr1_211941555_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-193b-5pchr12119415502119415567mer-m8211941549211941570142-19.28
ADediting_1517368chr1_211941555_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-193b-5pchr12119415502119415567mer-m8211941549211941570142-19.28
ADediting_1517368chr1_211941555_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-193b-5pchr12119415502119415567mer-m8211941549211941570142-19.28
ADediting_1517368chr1_211941555_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-193b-5pchr12119415502119415567mer-m8211941549211941570142-19.28
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-10399-5pchr12119416252119416317mer-m8211941624211941644140-10.39
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-6504-3pchr12119416252119416317mer-m8211941624211941648142-14.58
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-7151-3pchr12119416262119416338mer-1a211941626211941646146-15.79
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-10399-5pchr12119416252119416317mer-m8211941624211941644140-10.39
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-6504-3pchr12119416252119416317mer-m8211941624211941648142-14.58
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-7151-3pchr12119416262119416338mer-1a211941626211941646146-15.79
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-10399-5pchr12119416252119416317mer-m8211941624211941644140-10.39
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-6504-3pchr12119416252119416317mer-m8211941624211941648142-14.58
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-7151-3pchr12119416262119416338mer-1a211941626211941646146-15.79
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-10399-5pchr12119416252119416317mer-m8211941624211941644140-10.39
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-6504-3pchr12119416252119416317mer-m8211941624211941648142-14.58
ADediting_1517369chr1_211941627_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-7151-3pchr12119416262119416338mer-1a211941626211941646146-15.79
ADediting_63859chr1_211941486_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-562chr12119414832119414897mer-m8211941482211941502151-14.2
ADediting_63859chr1_211941486_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-5697chr12119414822119414887mer-m8211941481211941502146-18.01
ADediting_63859chr1_211941486_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-562chr12119414832119414897mer-m8211941482211941502151-14.2
ADediting_63859chr1_211941486_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-5697chr12119414822119414887mer-m8211941481211941502146-18.01
ADediting_63859chr1_211941486_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-562chr12119414832119414897mer-m8211941482211941502151-14.2
ADediting_63859chr1_211941486_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-5697chr12119414822119414887mer-m8211941481211941502146-18.01
ADediting_63861chr1_211941496_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-7151-3pchr12119414962119415027mer-m8211941495211941515140-16.94
ADediting_63861chr1_211941496_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-8052chr12119414902119414967mer-1a211941490211941510145-22.32
ADediting_63861chr1_211941496_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-7151-3pchr12119414962119415027mer-m8211941495211941515140-16.94
ADediting_63861chr1_211941496_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-8052chr12119414902119414967mer-1a211941490211941510145-22.32
ADediting_63861chr1_211941496_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-7151-3pchr12119414962119415027mer-m8211941495211941515140-16.94
ADediting_63861chr1_211941496_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-8052chr12119414902119414967mer-1a211941490211941510145-22.32
ADediting_63862chr1_211941506_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-4715-3pchr12119415062119415127mer-m8211941505211941527143-15.19
ADediting_63862chr1_211941506_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-4722-3pchr12119415042119415107mer-m8211941503211941522148-17.3
ADediting_63862chr1_211941506_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-4763-5pchr12119415032119415097mer-m8211941502211941520147-23.16
ADediting_63862chr1_211941506_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-6720-3pchr12119415012119415077mer-m8211941500211941521145-19.25
ADediting_63862chr1_211941506_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-4715-3pchr12119415062119415127mer-m8211941505211941527143-15.19
ADediting_63862chr1_211941506_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-4722-3pchr12119415042119415107mer-m8211941503211941522148-17.3
ADediting_63862chr1_211941506_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-4763-5pchr12119415032119415097mer-m8211941502211941520147-23.16
ADediting_63862chr1_211941506_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-6720-3pchr12119415012119415077mer-m8211941500211941521145-19.25
ADediting_63862chr1_211941506_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-4715-3pchr12119415062119415127mer-m8211941505211941527143-15.19
ADediting_63862chr1_211941506_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-4722-3pchr12119415042119415107mer-m8211941503211941522148-17.3
ADediting_63862chr1_211941506_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-4763-5pchr12119415032119415097mer-m8211941502211941520147-23.16
ADediting_63862chr1_211941506_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-6720-3pchr12119415012119415077mer-m8211941500211941521145-19.25
ADediting_63864chr1_211941522_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-4735-5pchr12119415212119415277mer-m8211941520211941541140-4.28
ADediting_63864chr1_211941522_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-4775chr12119415222119415287mer-m8211941521211941543153-6.63
ADediting_63864chr1_211941522_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-4735-5pchr12119415212119415277mer-m8211941520211941541140-4.28
ADediting_63864chr1_211941522_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-4775chr12119415222119415287mer-m8211941521211941543153-6.63
ADediting_63864chr1_211941522_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-4735-5pchr12119415212119415277mer-m8211941520211941541140-4.28
ADediting_63864chr1_211941522_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-4775chr12119415222119415287mer-m8211941521211941543153-6.63
ADediting_63866chr1_211941554_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-193b-5pchr12119415502119415567mer-m8211941549211941570142-19.28
ADediting_63866chr1_211941554_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-193b-5pchr12119415502119415567mer-m8211941549211941570142-19.28
ADediting_63866chr1_211941554_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-193b-5pchr12119415502119415567mer-m8211941549211941570142-19.28
ADediting_63866chr1_211941554_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-193b-5pchr12119415502119415567mer-m8211941549211941570142-19.28
ADediting_63867chr1_211941560_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-892achr12119415582119415647mer-m8211941557211941577140-15.2
ADediting_63867chr1_211941560_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-892achr12119415582119415647mer-m8211941557211941577140-15.2
ADediting_63867chr1_211941560_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-892achr12119415582119415647mer-m8211941557211941577140-15.2
ADediting_63867chr1_211941560_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-892achr12119415582119415647mer-m8211941557211941577140-15.2
ADediting_63868chr1_211941621_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-5089-5pchr12119416212119416277mer-m8211941620211941642153-18.02
ADediting_63868chr1_211941621_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-512-3pchr12119416162119416227mer-m8211941615211941636149-15.51
ADediting_63868chr1_211941621_-ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-6506-5pchr12119416202119416267mer-m8211941619211941644145-13.31
ADediting_63868chr1_211941621_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-5089-5pchr12119416212119416277mer-m8211941620211941642153-18.02
ADediting_63868chr1_211941621_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-512-3pchr12119416162119416227mer-m8211941615211941636149-15.51
ADediting_63868chr1_211941621_-ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-6506-5pchr12119416202119416267mer-m8211941619211941644145-13.31
ADediting_63868chr1_211941621_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-5089-5pchr12119416212119416277mer-m8211941620211941642153-18.02
ADediting_63868chr1_211941621_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-512-3pchr12119416162119416227mer-m8211941615211941636149-15.51
ADediting_63868chr1_211941621_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-6506-5pchr12119416202119416267mer-m8211941619211941644145-13.31
ADediting_63868chr1_211941621_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-5089-5pchr12119416212119416277mer-m8211941620211941642153-18.02
ADediting_63868chr1_211941621_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-512-3pchr12119416162119416227mer-m8211941615211941636149-15.51
ADediting_63868chr1_211941621_-ENSG00000143493.13ENST00000440600.6INTS7-204hsa-miR-6506-5pchr12119416202119416267mer-m8211941619211941644145-13.31

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1097295chr3_85385762_+ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-5688chr12119406982119407047mer-m8211940697211940721154-14.6
ADediting_1391023chr8_140732605_-ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-151a-3pchr12119410392119410468mer-1a211941039211941058141-12.03
ADediting_527135chr16_24203190_+ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-1273h-3pchr12119408892119408968mer-1a211940889211940910145-14.39
ADediting_843620chr2_207754818_+ENSG00000143493.13ENST00000366992.7INTS7-201hsa-miR-4775chr12119415222119415287mer-m8211941521211941543153-6.63
ADediting_843620chr2_207754818_+ENSG00000143493.13ENST00000366993.7INTS7-202hsa-miR-4775chr12119415222119415287mer-m8211941521211941543153-6.63
ADediting_843620chr2_207754818_+ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-4775chr12119409142119409218mer-1a211940914211940935152-8.08
ADediting_843620chr2_207754818_+ENSG00000143493.13ENST00000366994.8INTS7-203hsa-miR-4775chr12119415222119415287mer-m8211941521211941543153-6.63

check button Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for INTS7

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000366994.8protein_codingSoverviewSoverview
ENST00000366993.7protein_codingSoverviewSoverview
ENST00000366992.7protein_codingSoverviewSoverview
ENST00000440600.6protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_1517367ENST00000366994.8chr1_211941401_-3432-1291.90-1293.40-1304.80
ADediting_63858ENST00000366994.8chr1_211941454_-3379-1293.10-1293.40-1304.80
ADediting_63859ENST00000366994.8chr1_211941486_-3347-1297.10-1293.40-1304.80
ADediting_63860ENST00000366994.8chr1_211941490_-3343-1292.70-1293.40-1304.80
ADediting_63861ENST00000366994.8chr1_211941496_-3337-1295.40-1293.40-1304.80
ADediting_63862ENST00000366994.8chr1_211941506_-3327-1294.30-1293.40-1304.80
ADediting_63863ENST00000366994.8chr1_211941514_-3319-1293.40-1293.40-1304.80
ADediting_63864ENST00000366994.8chr1_211941522_-3311-1293.80-1293.40-1304.80
ADediting_63865ENST00000366994.8chr1_211941540_-3293-1296.10-1293.40-1304.80
ADediting_63866ENST00000366994.8chr1_211941554_-3279-1295.00-1293.40-1304.80
ADediting_1517368ENST00000366994.8chr1_211941555_-3278-1298.30-1293.40-1304.80
ADediting_63867ENST00000366994.8chr1_211941560_-3273-1295.00-1293.40-1304.80
ADediting_63868ENST00000366994.8chr1_211941621_-3212-1292.60-1293.40-1304.80
ADediting_1517369ENST00000366994.8chr1_211941627_-3206-1293.40-1293.40-1304.80
ADediting_1517367ENST00000366993.7chr1_211941401_-3369-1011.60-1013.10-1025.40
ADediting_63858ENST00000366993.7chr1_211941454_-3316-1013.40-1013.10-1025.40
ADediting_63859ENST00000366993.7chr1_211941486_-3284-1014.40-1013.10-1025.40
ADediting_63860ENST00000366993.7chr1_211941490_-3280-1013.10-1013.10-1025.40
ADediting_63861ENST00000366993.7chr1_211941496_-3274-1013.80-1013.10-1025.40
ADediting_63862ENST00000366993.7chr1_211941506_-3264-1014.00-1013.10-1025.40
ADediting_63863ENST00000366993.7chr1_211941514_-3256-1013.10-1013.10-1025.40
ADediting_63864ENST00000366993.7chr1_211941522_-3248-1014.70-1013.10-1025.40
ADediting_63865ENST00000366993.7chr1_211941540_-3230-1014.70-1013.10-1025.40
ADediting_63866ENST00000366993.7chr1_211941554_-3216-1013.90-1013.10-1025.40
ADediting_1517368ENST00000366993.7chr1_211941555_-3215-1016.90-1013.10-1025.40
ADediting_63867ENST00000366993.7chr1_211941560_-3210-1014.20-1013.10-1025.40
ADediting_63868ENST00000366993.7chr1_211941621_-3149-1012.30-1013.10-1025.40
ADediting_1517369ENST00000366993.7chr1_211941627_-3143-1013.10-1013.10-1025.40
ADediting_1517367ENST00000366992.7chr1_211941401_-3335-996.60-996.20-1008.90
ADediting_63858ENST00000366992.7chr1_211941454_-3282-996.70-996.20-1008.90
ADediting_63859ENST00000366992.7chr1_211941486_-3250-998.90-996.20-1008.90
ADediting_63860ENST00000366992.7chr1_211941490_-3246-995.70-996.20-1008.90
ADediting_63861ENST00000366992.7chr1_211941496_-3240-997.90-996.20-1008.90
ADediting_63862ENST00000366992.7chr1_211941506_-3230-997.40-996.20-1008.90
ADediting_63863ENST00000366992.7chr1_211941514_-3222-995.80-996.20-1008.90
ADediting_63864ENST00000366992.7chr1_211941522_-3214-997.30-996.20-1008.90
ADediting_63865ENST00000366992.7chr1_211941540_-3196-998.50-996.20-1008.90
ADediting_63866ENST00000366992.7chr1_211941554_-3182-998.30-996.20-1008.90
ADediting_1517368ENST00000366992.7chr1_211941555_-3181-1000.70-996.20-1008.90
ADediting_63867ENST00000366992.7chr1_211941560_-3176-997.40-996.20-1008.90
ADediting_63868ENST00000366992.7chr1_211941621_-3115-995.40-996.20-1008.90
ADediting_1517369ENST00000366992.7chr1_211941627_-3109-996.20-996.20-1008.90
ADediting_63865ENST00000440600.6chr1_211941540_-3128-914.40-914.40-915.40
ADediting_63866ENST00000440600.6chr1_211941554_-3114-916.50-914.40-915.40
ADediting_1517368ENST00000440600.6chr1_211941555_-3113-914.40-914.40-915.40
ADediting_63867ENST00000440600.6chr1_211941560_-3108-914.40-914.40-915.40
ADediting_63868ENST00000440600.6chr1_211941621_-3047-913.60-914.40-915.40
ADediting_1517369ENST00000440600.6chr1_211941627_-3041-914.40-914.40-915.40

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for INTS7

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_63862chr1_211941506_-0.1273883950104150.1250303875336649.78242218223759e-050.3127020550734330.01072217432911790.207798360189082
CERADediting_63867chr1_211941560_-0.02772761357544010.1797577888987933.64399972839279e-060.3678321120670670.09527216139606030.136712904110228
DLPFCADediting_63878chr1_211969226_-0.2574181554789970.06451610347088330.502488037094069-0.03822689668846551.55645120277624e-100.353130257820556
DLPFCADediting_63879chr1_211969238_-0.917180306378778-0.005929922374546340.102137419822957-0.09301221753034862.68454906595348e-110.366649288678061
DLPFCADediting_63882chr1_211969716_-0.3553936865277930.05266610019272730.273508177275199-0.06238433949218326.82100308198054e-160.437052874668026
DLPFCADediting_63888chr1_211969964_-0.5799134524194280.03155697202659780.206358226124215-0.07196773012046071.70695986501497e-190.482646660279346
DLPFCADediting_63890chr1_211969997_-0.815193109104012-0.01332833428338920.0307577429250939-0.1227223530891811.52187762839344e-140.418053106162223

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.23449947824878e-580.7560044951715859.77215750993631e-490.7095070170060493.56507967230453e-050.232508849477469
AC7.68024179731634e-1000.9151550216242495.73743080810938e-840.8842323425336382.44074765049336e-050.263498025162028
PCC2.03841828046615e-330.7326826383742099.53111535265779e-400.7763944530256590.004803388387901170.203243194174606
CER1.94821266864387e-120.5340727744907577.75500288679976e-220.6817597463619550.0004293427032645980.283951680569034
TCX5.56008420377935e-150.5821555538974080.001156896920118390.2628227758264553.03470222269779e-090.460527136236193
FP1.61999213558744e-220.6473268680783132.16267905442239e-320.7420471099300141.40073329054799e-050.3192651684937
IFG3.42571658112231e-050.7301447889226960.0001778040843535690.6811958383679920.002027964138139980.58722023374041
PG9.65389679260172e-530.8485001444916826.13379173784897e-240.652504311286170.4957573246985530.0502537779823508
STG1.09268529261055e-080.5746189265304747.76474424312386e-130.6835689096392130.04899018706304160.215498292126806

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Relation with AD stages for INTS7

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER0.00101696431530320.311879508334671
TCX0.0001992393989942640.353754631611197

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RelatedDrugs for INTS7

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for INTS7

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource