ADeditome: functional annotation of RNA A-to-I editing in AD

Gene summary for NBPF14

Gene summary

Gene information	Gene symbol	NBPF14
	Gene ID	25832
	Gene name	NBPF member 14
	Synonyms	DJ328E19.C1.1\|NBPF
	Cytomap	1q21.2
	Type of gene	protein-coding
	Description	neuroblastoma breakpoint family member 14AE5
	Modification date	20200313
	UniProtAcc	Q5TI25,
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

Top

RNA A-to-I events for NBPF14

RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA editing frequencies across three data sets.

The number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA A-to-I editing events in AD.

ADediting_16484(148531980, -), ADediting_16486(148532133, -), ADediting_16487(148532136, -), ADediting_16488(148532139, -), ADediting_16489(148532140, -), ADediting_16490(148532141, -), ADediting_16491(148532142, -), ADediting_16492(148532143, -), ADediting_16493(148532145, -), ADediting_16494(148532163, -), ADediting_16495(148532191, -),

Top

RNA editing positional annotations for NBPF14 using Annovar

Protein coding RNA editing(s).

ADeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

ADeditome ID	Position	Variant type
ADediting_16484	chr1_148531980_-	UTR3
ADediting_16486	chr1_148532133_-	UTR3
ADediting_16487	chr1_148532136_-	UTR3
ADediting_16488	chr1_148532139_-	UTR3
ADediting_16489	chr1_148532140_-	UTR3
ADediting_16490	chr1_148532141_-	UTR3
ADediting_16491	chr1_148532142_-	UTR3
ADediting_16492	chr1_148532143_-	UTR3
ADediting_16493	chr1_148532145_-	UTR3
ADediting_16494	chr1_148532163_-	UTR3
ADediting_16495	chr1_148532191_-	UTR3

Repat-regional RNA editing(s).

ADeditome ID	Position	Repeat family	Repeat sub family	Repeat name
ADediting_16484	chr1_148531980_-	LINE	L1	Name=L1MC4
ADediting_16486	chr1_148532133_-	LINE	L1	Name=L1MC4
ADediting_16487	chr1_148532136_-	LINE	L1	Name=L1MC4
ADediting_16488	chr1_148532139_-	LINE	L1	Name=L1MC4
ADediting_16489	chr1_148532140_-	LINE	L1	Name=L1MC4
ADediting_16490	chr1_148532141_-	LINE	L1	Name=L1MC4
ADediting_16491	chr1_148532142_-	LINE	L1	Name=L1MC4
ADediting_16492	chr1_148532143_-	LINE	L1	Name=L1MC4
ADediting_16493	chr1_148532145_-	LINE	L1	Name=L1MC4
ADediting_16494	chr1_148532163_-	LINE	L1	Name=L1MC4
ADediting_16495	chr1_148532191_-	LINE	L1	Name=L1MC4

Top

RNA A-to-I editing events in the alternative splicing sites for NBPF14

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

ADeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for NBPF14

Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

- Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

ADeditome ID

Chr

Positoing

Skipped exon

ENSG

ENSTs

Top

Protein coding region RNA A-to-I editings for NBPF14

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

Top

The effects of the RNA editing to the miRNA binding sites for NBPF14

RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

ADeditom_ID	Position	ENSG	ENST	Transcript name	miRNA ID	Chromosome	Targt	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
ADediting_16484	chr1_148531980_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-1199-5p	chr1	148531980	148531986	7mer-m8	148531979	148531997	150	-18.91
ADediting_16484	chr1_148531980_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-181b-2-3p	chr1	148531977	148531983	7mer-m8	148531976	148531994	145	-11.96
ADediting_16484	chr1_148531980_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-181b-3p	chr1	148531977	148531983	7mer-m8	148531976	148531995	149	-11.79
ADediting_16484	chr1_148531980_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-4420	chr1	148531977	148531983	7mer-m8	148531976	148531997	161	-25.99
ADediting_16484	chr1_148531980_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-6751-3p	chr1	148531980	148531986	7mer-m8	148531979	148531999	140	-18.55
ADediting_16484	chr1_148531980_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-1199-5p	chr1	148531980	148531986	7mer-m8	148531979	148531997	150	-18.91
ADediting_16484	chr1_148531980_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-181b-2-3p	chr1	148531977	148531983	7mer-m8	148531976	148531994	145	-11.96
ADediting_16484	chr1_148531980_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-181b-3p	chr1	148531977	148531983	7mer-m8	148531976	148531995	149	-11.79
ADediting_16484	chr1_148531980_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-4420	chr1	148531977	148531983	7mer-m8	148531976	148531997	161	-25.99
ADediting_16484	chr1_148531980_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-6751-3p	chr1	148531980	148531986	7mer-m8	148531979	148531999	140	-18.55
ADediting_16486	chr1_148532133_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-4279	chr1	148532129	148532135	7mer-m8	148532128	148532143	142	-14.13
ADediting_16486	chr1_148532133_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-6845-3p	chr1	148532133	148532139	7mer-m8	148532132	148532152	146	-19.78
ADediting_16486	chr1_148532133_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-7111-3p	chr1	148532131	148532137	7mer-m8	148532130	148532151	146	-14.36
ADediting_16486	chr1_148532133_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-4279	chr1	148532129	148532135	7mer-m8	148532128	148532143	142	-14.13
ADediting_16486	chr1_148532133_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-6845-3p	chr1	148532133	148532139	7mer-m8	148532132	148532152	146	-19.78
ADediting_16486	chr1_148532133_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-7111-3p	chr1	148532131	148532137	7mer-m8	148532130	148532151	146	-14.36
ADediting_16486	chr1_148532133_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-4279	chr1	148532129	148532135	7mer-m8	148532128	148532143	142	-14.13
ADediting_16486	chr1_148532133_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-6845-3p	chr1	148532133	148532139	7mer-m8	148532132	148532152	146	-19.78
ADediting_16486	chr1_148532133_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-7111-3p	chr1	148532131	148532137	7mer-m8	148532130	148532151	146	-14.36
ADediting_16487	chr1_148532136_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-6832-3p	chr1	148532136	148532142	7mer-m8	148532135	148532154	147	-9.85
ADediting_16487	chr1_148532136_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-6832-3p	chr1	148532136	148532142	7mer-m8	148532135	148532154	147	-9.85
ADediting_16487	chr1_148532136_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-6832-3p	chr1	148532136	148532142	7mer-m8	148532135	148532154	147	-9.85
ADediting_16488	chr1_148532139_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-204-5p	chr1	148532136	148532142	7mer-m8	148532135	148532157	141	-11.65
ADediting_16488	chr1_148532139_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-211-5p	chr1	148532136	148532142	7mer-m8	148532135	148532157	141	-11.65
ADediting_16488	chr1_148532139_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-4287	chr1	148532134	148532141	8mer-1a	148532134	148532152	140	-14.47
ADediting_16488	chr1_148532139_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-4685-3p	chr1	148532134	148532141	8mer-1a	148532134	148532155	140	-15.67
ADediting_16488	chr1_148532139_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-6832-3p	chr1	148532136	148532143	8mer-1a	148532136	148532155	143	-8.39
ADediting_16488	chr1_148532139_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-6867-3p	chr1	148532133	148532140	8mer-1a	148532133	148532153	147	-11.27
ADediting_16488	chr1_148532139_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-204-5p	chr1	148532136	148532142	7mer-m8	148532135	148532157	141	-11.65
ADediting_16488	chr1_148532139_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-211-5p	chr1	148532136	148532142	7mer-m8	148532135	148532157	141	-11.65
ADediting_16488	chr1_148532139_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-4287	chr1	148532134	148532141	8mer-1a	148532134	148532152	140	-14.47
ADediting_16488	chr1_148532139_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-4685-3p	chr1	148532134	148532141	8mer-1a	148532134	148532155	140	-15.67
ADediting_16488	chr1_148532139_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-6832-3p	chr1	148532136	148532143	8mer-1a	148532136	148532155	143	-8.39
ADediting_16488	chr1_148532139_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-6867-3p	chr1	148532133	148532140	8mer-1a	148532133	148532153	147	-11.27
ADediting_16488	chr1_148532139_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-204-5p	chr1	148532136	148532142	7mer-m8	148532135	148532157	141	-11.65
ADediting_16488	chr1_148532139_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-211-5p	chr1	148532136	148532142	7mer-m8	148532135	148532157	141	-11.65
ADediting_16488	chr1_148532139_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-4287	chr1	148532134	148532141	8mer-1a	148532134	148532152	140	-14.47
ADediting_16488	chr1_148532139_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-4685-3p	chr1	148532134	148532141	8mer-1a	148532134	148532155	140	-15.67
ADediting_16488	chr1_148532139_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-6832-3p	chr1	148532136	148532143	8mer-1a	148532136	148532155	143	-8.39
ADediting_16488	chr1_148532139_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-6867-3p	chr1	148532133	148532140	8mer-1a	148532133	148532153	147	-11.27
ADediting_16489	chr1_148532140_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-6844	chr1	148532139	148532145	7mer-m8	148532138	148532159	155	-9.16
ADediting_16489	chr1_148532140_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-6881-3p	chr1	148532136	148532142	7mer-m8	148532135	148532155	146	-11.27
ADediting_16489	chr1_148532140_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-6844	chr1	148532139	148532145	7mer-m8	148532138	148532159	155	-9.16
ADediting_16489	chr1_148532140_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-6881-3p	chr1	148532136	148532142	7mer-m8	148532135	148532155	146	-11.27
ADediting_16489	chr1_148532140_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-6844	chr1	148532139	148532145	7mer-m8	148532138	148532159	155	-9.16
ADediting_16489	chr1_148532140_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-6881-3p	chr1	148532136	148532142	7mer-m8	148532135	148532155	146	-11.27
ADediting_16490	chr1_148532141_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-1248	chr1	148532136	148532143	8mer-1a	148532136	148532163	155	-16.84
ADediting_16490	chr1_148532141_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-578	chr1	148532139	148532145	7mer-m8	148532138	148532156	148	-13.77
ADediting_16490	chr1_148532141_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-6868-3p	chr1	148532136	148532142	7mer-m8	148532135	148532156	163	-20.5
ADediting_16490	chr1_148532141_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-1248	chr1	148532136	148532143	8mer-1a	148532136	148532163	155	-16.84
ADediting_16490	chr1_148532141_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-578	chr1	148532139	148532145	7mer-m8	148532138	148532156	148	-13.77
ADediting_16490	chr1_148532141_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-6868-3p	chr1	148532136	148532142	7mer-m8	148532135	148532156	163	-20.5
ADediting_16490	chr1_148532141_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-1248	chr1	148532136	148532143	8mer-1a	148532136	148532163	155	-16.84
ADediting_16490	chr1_148532141_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-578	chr1	148532139	148532145	7mer-m8	148532138	148532156	148	-13.77
ADediting_16490	chr1_148532141_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-6868-3p	chr1	148532136	148532142	7mer-m8	148532135	148532156	163	-20.5
ADediting_16491	chr1_148532142_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-4652-3p	chr1	148532139	148532146	8mer-1a	148532139	148532160	140	-7.14
ADediting_16491	chr1_148532142_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-4652-3p	chr1	148532139	148532146	8mer-1a	148532139	148532160	140	-7.14
ADediting_16491	chr1_148532142_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-4652-3p	chr1	148532139	148532146	8mer-1a	148532139	148532160	140	-7.14
ADediting_16494	chr1_148532163_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-4802-3p	chr1	148532162	148532168	7mer-m8	148532161	148532183	141	-11.1
ADediting_16494	chr1_148532163_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-4802-3p	chr1	148532162	148532168	7mer-m8	148532161	148532183	141	-11.1
ADediting_16494	chr1_148532163_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-4802-3p	chr1	148532162	148532168	7mer-m8	148532161	148532183	141	-11.1

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

ADeditom_ID	Position	ENSG	ENST	Transcript name	miRNA ID	Chromosome	Targt	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
ADediting_16486	chr1_148532133_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-942-5p	chr1	148532131	148532137	7mer-1a	148532131	148532152	146	-20.42
ADediting_16486	chr1_148532133_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-942-5p	chr1	148532131	148532137	7mer-1a	148532131	148532152	146	-20.42
ADediting_16486	chr1_148532133_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-942-5p	chr1	148532131	148532137	7mer-1a	148532131	148532152	146	-20.42
ADediting_16487	chr1_148532136_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-942-5p	chr1	148532131	148532137	7mer-1a	148532131	148532152	146	-20.42
ADediting_16487	chr1_148532136_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-942-5p	chr1	148532131	148532137	7mer-1a	148532131	148532152	146	-20.42
ADediting_16487	chr1_148532136_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-942-5p	chr1	148532131	148532137	7mer-1a	148532131	148532152	146	-20.42
ADediting_16494	chr1_148532163_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-3689a-5p	chr1	148532159	148532165	7mer-m8	148532158	148532179	140	-10.31
ADediting_16494	chr1_148532163_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-3689b-5p	chr1	148532159	148532165	7mer-m8	148532158	148532179	140	-10.31
ADediting_16494	chr1_148532163_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-3689e	chr1	148532159	148532165	7mer-m8	148532158	148532179	140	-10.31
ADediting_16494	chr1_148532163_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-3689f	chr1	148532159	148532165	7mer-m8	148532158	148532178	146	-10.66
ADediting_16494	chr1_148532163_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-8076	chr1	148532162	148532168	7mer-m8	148532161	148532183	155	-12.69
ADediting_16494	chr1_148532163_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-3689a-5p	chr1	148532159	148532165	7mer-m8	148532158	148532179	140	-10.31
ADediting_16494	chr1_148532163_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-3689b-5p	chr1	148532159	148532165	7mer-m8	148532158	148532179	140	-10.31
ADediting_16494	chr1_148532163_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-3689e	chr1	148532159	148532165	7mer-m8	148532158	148532179	140	-10.31
ADediting_16494	chr1_148532163_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-3689f	chr1	148532159	148532165	7mer-m8	148532158	148532178	146	-10.66
ADediting_16494	chr1_148532163_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-8076	chr1	148532162	148532168	7mer-m8	148532161	148532183	155	-12.69
ADediting_16494	chr1_148532163_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-3689a-5p	chr1	148532159	148532165	7mer-m8	148532158	148532179	140	-10.31
ADediting_16494	chr1_148532163_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-3689b-5p	chr1	148532159	148532165	7mer-m8	148532158	148532179	140	-10.31
ADediting_16494	chr1_148532163_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-3689e	chr1	148532159	148532165	7mer-m8	148532158	148532179	140	-10.31
ADediting_16494	chr1_148532163_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-3689f	chr1	148532159	148532165	7mer-m8	148532158	148532178	146	-10.66
ADediting_16494	chr1_148532163_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-8076	chr1	148532162	148532168	7mer-m8	148532161	148532183	155	-12.69
ADediting_16495	chr1_148532191_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-223-3p	chr1	148532186	148532192	7mer-m8	148532185	148532205	146	-12.93
ADediting_16495	chr1_148532191_-	ENSG00000270629.6	ENST00000614999.4	NBPF14-205	hsa-miR-2355-3p	chr1	148532191	148532197	7mer-m8	148532190	148532210	147	-13.44
ADediting_16495	chr1_148532191_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-223-3p	chr1	148532186	148532192	7mer-m8	148532185	148532205	146	-12.93
ADediting_16495	chr1_148532191_-	ENSG00000270629.6	ENST00000619423.4	NBPF14-207	hsa-miR-2355-3p	chr1	148532191	148532197	7mer-m8	148532190	148532210	147	-13.44
ADediting_16495	chr1_148532191_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-223-3p	chr1	148532186	148532192	7mer-m8	148532185	148532205	146	-12.93
ADediting_16495	chr1_148532191_-	ENSG00000270629.6	ENST00000621066.4	NBPF14-209	hsa-miR-2355-3p	chr1	148532191	148532197	7mer-m8	148532190	148532210	147	-13.44

RNA A-to-I editing in lncRNA gained miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_1097295

chr3_85385762_+

ENSG00000270629.6

ENST00000614999.4

NBPF14-205

hsa-miR-5688

chr1

148531843

148531849

7mer-m8

148531842

148531866

143

-12.95

ADediting_1097295

chr3_85385762_+

ENSG00000270629.6

ENST00000619423.4

NBPF14-207

hsa-miR-5688

chr1

148531843

148531849

7mer-m8

148531842

148531866

143

-12.95

ADediting_1535951

chr14_100874558_+

ENSG00000270629.6

ENST00000614329.4

NBPF14-204

hsa-miR-337-3p

chr1

148533201

148533207

7mer-m8

148533200

148533223

154

-17.62

ADediting_1535951

chr14_100874558_+

ENSG00000270629.6

ENST00000616120.4

NBPF14-206

hsa-miR-337-3p

chr1

148533201

148533207

7mer-m8

148533200

148533223

154

-17.62

ADediting_1535951

chr14_100874558_+

ENSG00000270629.6

ENST00000620240.1

NBPF14-208

hsa-miR-337-3p

chr1

148533201

148533207

7mer-m8

148533200

148533223

154

-17.62

ADediting_1535954

chr14_101045974_+

ENSG00000270629.6

ENST00000614999.4

NBPF14-205

hsa-miR-381-3p

chr1

148531712

148531718

7mer-m8

148531711

148531732

141

-16.98

ADediting_1535954

chr14_101045974_+

ENSG00000270629.6

ENST00000619423.4

NBPF14-207

hsa-miR-381-3p

chr1

148531712

148531718

7mer-m8

148531711

148531732

141

-16.98

ADediting_1556067

chr19_40282625_-

ENSG00000270629.6

ENST00000614999.4

NBPF14-205

hsa-miR-641

chr1

148532689

148532695

7mer-m8

148532688

148532717

144

-19.81

ADediting_1556067

chr19_40282625_-

ENSG00000270629.6

ENST00000619423.4

NBPF14-207

hsa-miR-641

chr1

148532689

148532695

7mer-m8

148532688

148532717

144

-19.81

ADediting_1556067

chr19_40282625_-

ENSG00000270629.6

ENST00000621066.4

NBPF14-209

hsa-miR-641

chr1

148532689

148532695

7mer-m8

148532688

148532717

144

-19.81

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_1556067

chr19_40282625_-

ENSG00000270629.6

ENST00000614999.4

NBPF14-205

hsa-miR-641

chr1

148531946

148531952

7mer-m8

148531945

148531971

147

-15.43

ADediting_1556067

chr19_40282625_-

ENSG00000270629.6

ENST00000619423.4

NBPF14-207

hsa-miR-641

chr1

148531946

148531952

7mer-m8

148531945

148531971

147

-15.43

ADediting_1631458

chr19_40282624_-

ENSG00000270629.6

ENST00000614999.4

NBPF14-205

hsa-miR-641

chr1

148531946

148531952

7mer-m8

148531945

148531971

147

-15.43

ADediting_1631458

chr19_40282624_-

ENSG00000270629.6

ENST00000619423.4

NBPF14-207

hsa-miR-641

chr1

148531946

148531952

7mer-m8

148531945

148531971

147

-15.43

Differentially expressed gene-miRNA network

Differentially expressed mRNA-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for NBPF14

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000614999.4	protein_coding
ENST00000619423.4	protein_coding
ENST00000621066.4	protein_coding

RNA A-to-I editing in miRNA.

ADeditom_ID

ENST

mir_ID

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

RNA A-to-I editing in mRNA.

ADeditom_ID	ENST	Editing_Information	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
ADediting_16484	ENST00000614999.4	chr1_148531980_-	9485	-3242.19	-3235.99	-3258.79
ADediting_16486	ENST00000614999.4	chr1_148532133_-	9332	-3242.59	-3235.99	-3258.79
ADediting_16487	ENST00000614999.4	chr1_148532136_-	9329	-3235.39	-3235.99	-3258.79
ADediting_16488	ENST00000614999.4	chr1_148532139_-	9326	-3235.69	-3235.99	-3258.79
ADediting_16489	ENST00000614999.4	chr1_148532140_-	9325	-3236.09	-3235.99	-3258.79
ADediting_16490	ENST00000614999.4	chr1_148532141_-	9324	-3236.09	-3235.99	-3258.79
ADediting_16491	ENST00000614999.4	chr1_148532142_-	9323	-3236.09	-3235.99	-3258.79
ADediting_16492	ENST00000614999.4	chr1_148532143_-	9322	-3235.69	-3235.99	-3258.79
ADediting_16493	ENST00000614999.4	chr1_148532145_-	9320	-3235.99	-3235.99	-3258.79
ADediting_16494	ENST00000614999.4	chr1_148532163_-	9302	-3242.19	-3235.99	-3258.79
ADediting_16495	ENST00000614999.4	chr1_148532191_-	9274	-3242.69	-3235.99	-3258.79
ADediting_16484	ENST00000619423.4	chr1_148531980_-	10184	-3475.29	-3469.09	-3491.89
ADediting_16486	ENST00000619423.4	chr1_148532133_-	10031	-3475.69	-3469.09	-3491.89
ADediting_16487	ENST00000619423.4	chr1_148532136_-	10028	-3468.49	-3469.09	-3491.89
ADediting_16488	ENST00000619423.4	chr1_148532139_-	10025	-3468.79	-3469.09	-3491.89
ADediting_16489	ENST00000619423.4	chr1_148532140_-	10024	-3469.19	-3469.09	-3491.89
ADediting_16490	ENST00000619423.4	chr1_148532141_-	10023	-3469.19	-3469.09	-3491.89
ADediting_16491	ENST00000619423.4	chr1_148532142_-	10022	-3469.19	-3469.09	-3491.89
ADediting_16492	ENST00000619423.4	chr1_148532143_-	10021	-3468.79	-3469.09	-3491.89
ADediting_16493	ENST00000619423.4	chr1_148532145_-	10019	-3469.09	-3469.09	-3491.89
ADediting_16494	ENST00000619423.4	chr1_148532163_-	10001	-3475.29	-3469.09	-3491.89
ADediting_16495	ENST00000619423.4	chr1_148532191_-	9973	-3475.79	-3469.09	-3491.89
ADediting_16486	ENST00000621066.4	chr1_148532133_-	3655	-1162.50	-1159.90	-1168.30
ADediting_16487	ENST00000621066.4	chr1_148532136_-	3652	-1159.90	-1159.90	-1168.30
ADediting_16488	ENST00000621066.4	chr1_148532139_-	3649	-1159.90	-1159.90	-1168.30
ADediting_16489	ENST00000621066.4	chr1_148532140_-	3648	-1159.90	-1159.90	-1168.30
ADediting_16490	ENST00000621066.4	chr1_148532141_-	3647	-1161.50	-1159.90	-1168.30
ADediting_16491	ENST00000621066.4	chr1_148532142_-	3646	-1159.90	-1159.90	-1168.30
ADediting_16492	ENST00000621066.4	chr1_148532143_-	3645	-1159.90	-1159.90	-1168.30
ADediting_16493	ENST00000621066.4	chr1_148532145_-	3643	-1161.10	-1159.90	-1168.30
ADediting_16494	ENST00000621066.4	chr1_148532163_-	3625	-1162.20	-1159.90	-1168.30
ADediting_16495	ENST00000621066.4	chr1_148532191_-	3597	-1161.10	-1159.90	-1168.30

RNA A-to-I editing in lncRNA.

ADeditom_ID

ENST

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

Top

Relation with ADAR for NBPF14

Correlation between ADAR gene expression and RNA editing frequency

Tissue	ADeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
AC	ADediting_16484	chr1_148531980_-	2.31509208979404e-09	0.366441189422151	1.18754850253854e-06	0.301557574140707	1.76588374253716e-11	0.40861293297061
TCX	ADediting_16484	chr1_148531980_-	0.153003422046125	-0.117255599587269	0.000852690175969546	-0.269507621687554	0.000128563968032514	0.307610097383766
CER	ADediting_16488	chr1_148532139_-	1.4655991133022e-05	0.345768578901577	2.60705035238756e-05	0.336130622499346	0.0665015480621142	-0.150234649243752

Correlation between ADAR gene expression and this gene's expression

Tissue	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
DLPFC	3.63235263856826e-05	0.232273868903042	0.231771653676198	0.0681135666810515	2.08115355610925e-46	0.697041073807763
AC	9.78331411409463e-10	0.374341786773409	2.83522353167228e-05	0.261455958796146	5.6427241303016e-28	0.620280951568473
PCC	0.994864396757558	-0.00046881115475951	0.612205372401619	-0.0369098036199251	3.28827605503117e-17	0.560732846828008
CER	1.63088489845645e-16	0.607733142375303	9.60623838546104e-13	0.540300624086029	2.10714675662418e-07	0.408512946335356
TCX	0.0556724297018665	0.156588734892816	0.178752989864454	-0.110374079705486	3.15608444852737e-10	0.485089407098487
FP	5.7288362584342e-07	0.364378243880504	0.0020453071263637	0.229644624198361	5.49110530667181e-11	0.466119560140978
IFG	0.0229274795197916	0.453109452263459	0.00682969152413419	0.526711928619967	0.000569988630487391	0.640012078223386
PG	3.47054228849182e-12	0.481499285370925	4.74104806610636e-08	0.387277094978458	0.00520228890303091	0.204097887794114
STG	0.153279317939977	0.157197194556544	0.953048728746629	-0.00652184767286801	9.84441949498724e-08	0.542420043981593

Top

Relation with AD stages for NBPF14

Correlation between AD stages and RNA editing frequency

Tissue

ADeditomID

position

P-val

Coeff.

Correlation between AD stages and this gene's expression

Tissue	P-val	Coeff.
CER	6.68427907829926e-05	0.374004973212277
TCX	6.67730053555849e-09	0.526652838010071
IFG	0.0402140309698017	0.412932809274726

Top

RelatedDrugs for NBPF14

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

RelatedDiseases for NBPF14

Diseases associated with this gene.
(DisGeNet 4.0)

Gene

Disease ID

Disease name

# pubmeds

Source

Home

Download

Statistics

Landscape

Help

Contact

Gene summary for NBPF14

RNA A-to-I events for NBPF14

RNA editing positional annotations for NBPF14 using Annovar

RNA A-to-I editing events in the alternative splicing sites for NBPF14

Differntial gene expression between RNA A-to-I edited versus non-edited samples for NBPF14

Protein coding region RNA A-to-I editings for NBPF14

The effects of the RNA editing to the miRNA binding sites for NBPF14

The effects of the RNA editing to the stability of the RNA structures for NBPF14

Relation with ADAR for NBPF14

Relation with AD stages for NBPF14

RelatedDrugs for NBPF14

RelatedDiseases for NBPF14

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited versus non-edited samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with AD stages
	Related drugs with this gene
	Related diseases with this gene