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Center for Computational Systems Medicine
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Gene summary

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RNA A-to-I events

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Differntial gene expression between RNA A-to-I edited versus non-edited samples

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Protein coding region RNA A-to-I editings

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The effects of the RNA editing to the miRNA binding sites

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The effects of the RNA editing to the stability of the RNA structures

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Relation with ADAR

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Relation with AD stages

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Related drugs with this gene

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Related diseases with this gene


Gene summary for SVIP

check button Gene summary
Gene informationGene symbol

SVIP

Gene ID

258010

Gene namesmall VCP interacting protein
Synonyms-
Cytomap

11p14.3

Type of geneprotein-coding
Descriptionsmall VCP/p97-interacting protein
Modification date20200313
UniProtAcc

Q8NHG7,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for SVIP

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_247125(22816307, -), ADediting_247126(22816416, -), ADediting_247127(22816487, -), ADediting_247128(22816488, -), ADediting_247129(22816504, -), ADediting_247130(22819515, -), ADediting_247131(22819624, -), ADediting_247132(22819660, -), ADediting_247133(22819689, -), ADediting_247134(22819690, -), ADediting_247135(22819696, -), ADediting_247136(22819720, -), ADediting_1526609(22819623, -),

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RNA editing positional annotations for SVIP using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_247125chr11_22816307_-intergenic
ADediting_247126chr11_22816416_-intergenic
ADediting_247127chr11_22816487_-intergenic
ADediting_247128chr11_22816488_-intergenic
ADediting_247129chr11_22816504_-intergenic
ADediting_247130chr11_22819515_-UTR3
ADediting_247131chr11_22819624_-UTR3
ADediting_247132chr11_22819660_-UTR3
ADediting_247133chr11_22819689_-UTR3
ADediting_247134chr11_22819690_-UTR3
ADediting_247135chr11_22819696_-UTR3
ADediting_247136chr11_22819720_-UTR3
ADediting_1526609chr11_22819623_-UTR3

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_247125chr11_22816307_-SINEAluName=AluSz
ADediting_247126chr11_22816416_-SINEAluName=AluSz
ADediting_247127chr11_22816487_-SINEAluName=AluSz
ADediting_247128chr11_22816488_-SINEAluName=AluSz
ADediting_247129chr11_22816504_-SINEAluName=AluSz
ADediting_247130chr11_22819515_-SINEAluName=AluSp
ADediting_247131chr11_22819624_-SINEAluName=AluSp
ADediting_247132chr11_22819660_-SINEAluName=AluSp
ADediting_247133chr11_22819689_-SINEAluName=AluSp
ADediting_247134chr11_22819690_-SINEAluName=AluSp
ADediting_247135chr11_22819696_-SINEAluName=AluSp
ADediting_247136chr11_22819720_-SINEAluName=AluSp
ADediting_1526609chr11_22819623_-SINEAluName=AluSp

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RNA A-to-I editing events in the alternative splicing sites for SVIP

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SVIP

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs