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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for LINC00957 |
 Gene summary |
| Gene information | Gene symbol | LINC00957 | Gene ID | 255031 |
| Gene name | long intergenic non-protein coding RNA 957 | |
| Synonyms | - | |
| Cytomap | 7p13 | |
| Type of gene | ncRNA | |
| Description | - | |
| Modification date | 20200313 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for LINC00957 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_1332825(44042047, +), ADediting_1332826(44042053, +), ADediting_1332827(44042054, +), ADediting_1332828(44042059, +), ADediting_1332829(44042075, +), ADediting_1332830(44042076, +), ADediting_1332831(44042084, +), ADediting_1332832(44042097, +), ADediting_1332833(44042098, +), ADediting_1332834(44042121, +), ADediting_1332835(44042130, +), ADediting_1332836(44042131, +), ADediting_1332837(44042142, +), ADediting_1332838(44042145, +), ADediting_1332839(44042151, +), ADediting_1332840(44042154, +), ADediting_1332841(44042156, +), ADediting_1332842(44042168, +), ADediting_1332843(44042186, +), ADediting_1332844(44042192, +), ADediting_1332845(44042196, +), ADediting_1332846(44042200, +), ADediting_1332847(44042209, +), ADediting_1332848(44042213, +), ADediting_1332849(44042222, +), ADediting_1332850(44042227, +), ADediting_1332851(44042228, +), ADediting_1332852(44042302, +), ADediting_1587511(44042092, +), ADediting_1587512(44042239, +), |
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RNA editing positional annotations for LINC00957 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1332825 | chr7_44042047_+ | ncRNA_exonic |
| ADediting_1332826 | chr7_44042053_+ | ncRNA_exonic |
| ADediting_1332827 | chr7_44042054_+ | ncRNA_exonic |
| ADediting_1332828 | chr7_44042059_+ | ncRNA_exonic |
| ADediting_1332829 | chr7_44042075_+ | ncRNA_exonic |
| ADediting_1332830 | chr7_44042076_+ | ncRNA_exonic |
| ADediting_1332831 | chr7_44042084_+ | ncRNA_exonic |
| ADediting_1332832 | chr7_44042097_+ | ncRNA_exonic |
| ADediting_1332833 | chr7_44042098_+ | ncRNA_exonic |
| ADediting_1332834 | chr7_44042121_+ | ncRNA_exonic |
| ADediting_1332835 | chr7_44042130_+ | ncRNA_exonic |
| ADediting_1332836 | chr7_44042131_+ | ncRNA_exonic |
| ADediting_1332837 | chr7_44042142_+ | ncRNA_exonic |
| ADediting_1332838 | chr7_44042145_+ | ncRNA_exonic |
| ADediting_1332839 | chr7_44042151_+ | ncRNA_exonic |
| ADediting_1332840 | chr7_44042154_+ | ncRNA_exonic |
| ADediting_1332841 | chr7_44042156_+ | ncRNA_exonic |
| ADediting_1332842 | chr7_44042168_+ | ncRNA_exonic |
| ADediting_1332843 | chr7_44042186_+ | ncRNA_exonic |
| ADediting_1332844 | chr7_44042192_+ | ncRNA_exonic |
| ADediting_1332845 | chr7_44042196_+ | ncRNA_exonic |
| ADediting_1332846 | chr7_44042200_+ | ncRNA_exonic |
| ADediting_1332847 | chr7_44042209_+ | ncRNA_exonic |
| ADediting_1332848 | chr7_44042213_+ | ncRNA_exonic |
| ADediting_1332849 | chr7_44042222_+ | ncRNA_exonic |
| ADediting_1332850 | chr7_44042227_+ | ncRNA_exonic |
| ADediting_1332851 | chr7_44042228_+ | ncRNA_exonic |
| ADediting_1332852 | chr7_44042302_+ | ncRNA_exonic |
| ADediting_1587511 | chr7_44042092_+ | ncRNA_exonic |
| ADediting_1587512 | chr7_44042239_+ | ncRNA_exonic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1332825 | chr7_44042047_+ | SINE | Alu | Name=AluSc |
| ADediting_1332826 | chr7_44042053_+ | SINE | Alu | Name=AluSc |
| ADediting_1332827 | chr7_44042054_+ | SINE | Alu | Name=AluSc |
| ADediting_1332828 | chr7_44042059_+ | SINE | Alu | Name=AluSc |
| ADediting_1332829 | chr7_44042075_+ | SINE | Alu | Name=AluSc |
| ADediting_1332830 | chr7_44042076_+ | SINE | Alu | Name=AluSc |
| ADediting_1332831 | chr7_44042084_+ | SINE | Alu | Name=AluSc |
| ADediting_1332832 | chr7_44042097_+ | SINE | Alu | Name=AluSc |
| ADediting_1332833 | chr7_44042098_+ | SINE | Alu | Name=AluSc |
| ADediting_1332834 | chr7_44042121_+ | SINE | Alu | Name=AluSc |
| ADediting_1332835 | chr7_44042130_+ | SINE | Alu | Name=AluSc |
| ADediting_1332836 | chr7_44042131_+ | SINE | Alu | Name=AluSc |
| ADediting_1332837 | chr7_44042142_+ | SINE | Alu | Name=AluSc |
| ADediting_1332838 | chr7_44042145_+ | SINE | Alu | Name=AluSc |
| ADediting_1332839 | chr7_44042151_+ | SINE | Alu | Name=AluSc |
| ADediting_1332840 | chr7_44042154_+ | SINE | Alu | Name=AluSc |
| ADediting_1332841 | chr7_44042156_+ | SINE | Alu | Name=AluSc |
| ADediting_1332842 | chr7_44042168_+ | SINE | Alu | Name=AluSc |
| ADediting_1332843 | chr7_44042186_+ | SINE | Alu | Name=AluSc |
| ADediting_1332844 | chr7_44042192_+ | SINE | Alu | Name=AluSc |
| ADediting_1332845 | chr7_44042196_+ | SINE | Alu | Name=AluSc |
| ADediting_1332846 | chr7_44042200_+ | SINE | Alu | Name=AluSc |
| ADediting_1332847 | chr7_44042209_+ | SINE | Alu | Name=AluSc |
| ADediting_1332848 | chr7_44042213_+ | SINE | Alu | Name=AluSc |
| ADediting_1332849 | chr7_44042222_+ | SINE | Alu | Name=AluSc |
| ADediting_1332850 | chr7_44042227_+ | SINE | Alu | Name=AluSc |
| ADediting_1332851 | chr7_44042228_+ | SINE | Alu | Name=AluSc |
| ADediting_1332852 | chr7_44042302_+ | SINE | Alu | Name=AluSc |
| ADediting_1587511 | chr7_44042092_+ | SINE | Alu | Name=AluSc |
| ADediting_1587512 | chr7_44042239_+ | SINE | Alu | Name=AluSc |
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RNA A-to-I editing events in the alternative splicing sites for LINC00957 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for LINC00957 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for LINC00957 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for LINC00957 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1332826 | chr7_44042053_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-513a-5p | chr7 | 44042048 | 44042054 | 7mer-m8 | 44042038 | 44042055 | 144 | -17.77 |
| ADediting_1332826 | chr7_44042053_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-638 | chr7 | 44042053 | 44042059 | 7mer-1a | 44042035 | 44042059 | 151 | -33.99 |
| ADediting_1332830 | chr7_44042076_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-3176 | chr7 | 44042070 | 44042076 | 7mer-m8 | 44042057 | 44042077 | 143 | -17.19 |
| ADediting_1332830 | chr7_44042076_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-3620-3p | chr7 | 44042074 | 44042080 | 7mer-m8 | 44042059 | 44042081 | 156 | -24.24 |
| ADediting_1332830 | chr7_44042076_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-3922-3p | chr7 | 44042070 | 44042076 | 7mer-m8 | 44042056 | 44042077 | 141 | -20.4 |
| ADediting_1332833 | chr7_44042098_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-378a-5p | chr7 | 44042094 | 44042100 | 7mer-m8 | 44042080 | 44042101 | 153 | -23.97 |
| ADediting_1332834 | chr7_44042121_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-3190-5p | chr7 | 44042115 | 44042121 | 7mer-m8 | 44042103 | 44042122 | 150 | -18.87 |
| ADediting_1332835 | chr7_44042130_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-1182 | chr7 | 44042129 | 44042136 | 8mer-1a | 44042114 | 44042136 | 143 | -15.71 |
| ADediting_1332835 | chr7_44042130_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-1229-3p | chr7 | 44042125 | 44042131 | 7mer-m8 | 44042108 | 44042132 | 146 | -16.14 |
| ADediting_1332835 | chr7_44042130_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-6511a-3p | chr7 | 44042124 | 44042131 | 8mer-1a | 44042110 | 44042131 | 145 | -15.2 |
| ADediting_1332835 | chr7_44042130_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-6511b-3p | chr7 | 44042124 | 44042131 | 8mer-1a | 44042109 | 44042131 | 140 | -13.68 |
| ADediting_1332836 | chr7_44042131_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-3158-3p | chr7 | 44042129 | 44042136 | 8mer-1a | 44042116 | 44042136 | 150 | -20.03 |
| ADediting_1332836 | chr7_44042131_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-412-3p | chr7 | 44042125 | 44042131 | 7mer-m8 | 44042110 | 44042132 | 151 | -16.53 |
| ADediting_1332836 | chr7_44042131_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-6754-3p | chr7 | 44042125 | 44042131 | 7mer-m8 | 44042112 | 44042132 | 144 | -15.76 |
| ADediting_1332837 | chr7_44042142_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-374b-3p | chr7 | 44042140 | 44042147 | 8mer-1a | 44042122 | 44042147 | 150 | -14.59 |
| ADediting_1332837 | chr7_44042142_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-4756-3p | chr7 | 44042136 | 44042142 | 7mer-m8 | 44042120 | 44042143 | 149 | -15.72 |
| ADediting_1332838 | chr7_44042145_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-222-5p | chr7 | 44042140 | 44042147 | 8mer-1a | 44042129 | 44042147 | 144 | -11.65 |
| ADediting_1332838 | chr7_44042145_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-30a-3p | chr7 | 44042142 | 44042149 | 8mer-1a | 44042125 | 44042149 | 154 | -10.8 |
| ADediting_1332838 | chr7_44042145_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-30d-3p | chr7 | 44042142 | 44042149 | 8mer-1a | 44042124 | 44042149 | 151 | -10.92 |
| ADediting_1332838 | chr7_44042145_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-30e-3p | chr7 | 44042142 | 44042149 | 8mer-1a | 44042125 | 44042149 | 154 | -12.66 |
| ADediting_1332838 | chr7_44042145_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-936 | chr7 | 44042139 | 44042146 | 8mer-1a | 44042124 | 44042146 | 159 | -24.07 |
| ADediting_1332839 | chr7_44042151_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-153-5p | chr7 | 44042145 | 44042151 | 7mer-m8 | 44042129 | 44042152 | 147 | -8.22 |
| ADediting_1332839 | chr7_44042151_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-3680-3p | chr7 | 44042149 | 44042156 | 8mer-1a | 44042134 | 44042156 | 140 | -14.34 |
| ADediting_1332840 | chr7_44042154_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-4742-3p | chr7 | 44042148 | 44042155 | 8mer-1a | 44042133 | 44042155 | 142 | -9.18 |
| ADediting_1332841 | chr7_44042156_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-6844 | chr7 | 44042151 | 44042157 | 7mer-m8 | 44042137 | 44042158 | 155 | -7.49 |
| ADediting_1332843 | chr7_44042186_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-140-3p | chr7 | 44042182 | 44042188 | 7mer-m8 | 44042169 | 44042189 | 155 | -21.26 |
| ADediting_1332845 | chr7_44042196_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-1207-3p | chr7 | 44042190 | 44042196 | 7mer-m8 | 44042179 | 44042197 | 145 | -13.53 |
| ADediting_1332845 | chr7_44042196_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-646 | chr7 | 44042192 | 44042198 | 7mer-m8 | 44042180 | 44042199 | 148 | -21.05 |
| ADediting_1332847 | chr7_44042209_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-1913 | chr7 | 44042208 | 44042214 | 7mer-m8 | 44042196 | 44042215 | 148 | -25.01 |
| ADediting_1332847 | chr7_44042209_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-6849-3p | chr7 | 44042203 | 44042209 | 7mer-m8 | 44042188 | 44042210 | 141 | -14.9 |
| ADediting_1332850 | chr7_44042227_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-3691-3p | chr7 | 44042222 | 44042228 | 7mer-1a | 44042213 | 44042234 | 168 | -18.74 |
| ADediting_1587512 | chr7_44042239_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-1281 | chr7 | 44042233 | 44042239 | 7mer-m8 | 44042224 | 44042240 | 141 | -17.01 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1332825 | chr7_44042047_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-3934-5p | chr7 | 44042045 | 44042051 | 7mer-m8 | 44042030 | 44042052 | 147 | -21.08 |
| ADediting_1332825 | chr7_44042047_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-552-3p | chr7 | 44042046 | 44042053 | 8mer-1a | 44042033 | 44042053 | 140 | -14.35 |
| ADediting_1332826 | chr7_44042053_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-10399-5p | chr7 | 44042049 | 44042055 | 7mer-m8 | 44042035 | 44042056 | 148 | -10 |
| ADediting_1332826 | chr7_44042053_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-6504-3p | chr7 | 44042049 | 44042055 | 7mer-m8 | 44042035 | 44042056 | 145 | -18.79 |
| ADediting_1332827 | chr7_44042054_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-10399-5p | chr7 | 44042049 | 44042055 | 7mer-m8 | 44042035 | 44042056 | 148 | -10 |
| ADediting_1332827 | chr7_44042054_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-5089-5p | chr7 | 44042053 | 44042059 | 7mer-m8 | 44042038 | 44042060 | 148 | -13.62 |
| ADediting_1332827 | chr7_44042054_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-6504-3p | chr7 | 44042049 | 44042055 | 7mer-m8 | 44042035 | 44042056 | 145 | -18.79 |
| ADediting_1332828 | chr7_44042059_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-1278 | chr7 | 44042058 | 44042064 | 7mer-m8 | 44042044 | 44042065 | 147 | -9.54 |
| ADediting_1332828 | chr7_44042059_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-5089-5p | chr7 | 44042053 | 44042059 | 7mer-m8 | 44042038 | 44042060 | 148 | -13.62 |
| ADediting_1332828 | chr7_44042059_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-6506-5p | chr7 | 44042054 | 44042060 | 7mer-m8 | 44042039 | 44042061 | 144 | -14.65 |
| ADediting_1332829 | chr7_44042075_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-6878-3p | chr7 | 44042069 | 44042076 | 8mer-1a | 44042056 | 44042076 | 142 | -14.81 |
| ADediting_1332834 | chr7_44042121_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-4716-5p | chr7 | 44042120 | 44042126 | 7mer-m8 | 44042106 | 44042127 | 140 | -11.3 |
| ADediting_1332834 | chr7_44042121_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-4781-3p | chr7 | 44042118 | 44042124 | 7mer-m8 | 44042104 | 44042125 | 140 | -14.54 |
| ADediting_1332837 | chr7_44042142_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-6832-5p | chr7 | 44042137 | 44042143 | 7mer-m8 | 44042122 | 44042144 | 140 | -18.59 |
| ADediting_1332842 | chr7_44042168_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-6872-3p | chr7 | 44042165 | 44042171 | 7mer-m8 | 44042152 | 44042172 | 141 | -12.32 |
| ADediting_1332843 | chr7_44042186_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-7151-3p | chr7 | 44042180 | 44042186 | 7mer-m8 | 44042167 | 44042187 | 140 | -17.86 |
| ADediting_1332843 | chr7_44042186_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-8052 | chr7 | 44042186 | 44042192 | 7mer-1a | 44042172 | 44042192 | 141 | -25.19 |
| ADediting_1332845 | chr7_44042196_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-6869-5p | chr7 | 44042194 | 44042200 | 7mer-m8 | 44042177 | 44042201 | 153 | -22.99 |
| ADediting_1332846 | chr7_44042200_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-1200 | chr7 | 44042197 | 44042203 | 7mer-m8 | 44042183 | 44042204 | 141 | -18.61 |
| ADediting_1332846 | chr7_44042200_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-6869-5p | chr7 | 44042194 | 44042200 | 7mer-m8 | 44042177 | 44042201 | 153 | -22.99 |
| ADediting_1332848 | chr7_44042213_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-1976 | chr7 | 44042211 | 44042218 | 8mer-1a | 44042198 | 44042218 | 153 | -25.04 |
| ADediting_1332848 | chr7_44042213_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-6747-3p | chr7 | 44042209 | 44042216 | 8mer-1a | 44042194 | 44042216 | 149 | -23.42 |
| ADediting_1332849 | chr7_44042222_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-26a-5p | chr7 | 44042221 | 44042228 | 8mer-1a | 44042207 | 44042228 | 152 | -13.83 |
| ADediting_1332849 | chr7_44042222_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-4465 | chr7 | 44042221 | 44042228 | 8mer-1a | 44042202 | 44042228 | 148 | -16.7 |
| ADediting_1332849 | chr7_44042222_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-5697 | chr7 | 44042221 | 44042227 | 7mer-1a | 44042205 | 44042227 | 142 | -15.92 |
| ADediting_1332850 | chr7_44042227_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-26a-5p | chr7 | 44042221 | 44042228 | 8mer-1a | 44042207 | 44042228 | 152 | -13.83 |
| ADediting_1332850 | chr7_44042227_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-4465 | chr7 | 44042221 | 44042228 | 8mer-1a | 44042202 | 44042228 | 148 | -16.7 |
| ADediting_1587511 | chr7_44042092_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-6790-3p | chr7 | 44042090 | 44042097 | 8mer-1a | 44042077 | 44042097 | 147 | -20.4 |
| ADediting_1587512 | chr7_44042239_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-6836-3p | chr7 | 44042233 | 44042239 | 7mer-m8 | 44042220 | 44042240 | 145 | -17.9 |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_107020 | chr1_37500952_- | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-5581-3p | chr7 | 44041426 | 44041432 | 7mer-m8 | 44041412 | 44041433 | 154 | -25.97 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000235314.1 | ENST00000416824.1 | LINC00957-201 | hsa-miR-589-5p | chr7 | 44040497 | 44040503 | 7mer-m8 | 44040484 | 44040504 | 154 | -20.01 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-589-5p | chr7 | 44040497 | 44040503 | 7mer-m8 | 44040484 | 44040504 | 154 | -20.01 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000235314.1 | ENST00000416824.1 | LINC00957-201 | hsa-miR-151a-3p | chr7 | 44040165 | 44040171 | 7mer-m8 | 44040152 | 44040172 | 147 | -20.58 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000235314.1 | ENST00000416824.1 | LINC00957-201 | hsa-miR-151a-3p | chr7 | 44040535 | 44040542 | 8mer-1a | 44040523 | 44040542 | 143 | -16.69 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-151a-3p | chr7 | 44040165 | 44040171 | 7mer-m8 | 44040152 | 44040172 | 147 | -20.58 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-151a-3p | chr7 | 44040535 | 44040542 | 8mer-1a | 44040523 | 44040542 | 143 | -16.69 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000235314.1 | ENST00000416824.1 | LINC00957-201 | hsa-miR-4477b | chr7 | 44041025 | 44041032 | 8mer-1a | 44041011 | 44041032 | 148 | -13.07 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-4477b | chr7 | 44041025 | 44041032 | 8mer-1a | 44041011 | 44041032 | 148 | -13.07 |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000235314.1 | ENST00000416824.1 | LINC00957-201 | hsa-miR-4477b | chr7 | 44040983 | 44040989 | 7mer-m8 | 44040968 | 44040990 | 144 | -9.46 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-4477b | chr7 | 44040983 | 44040989 | 7mer-m8 | 44040968 | 44040990 | 144 | -9.46 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000235314.1 | ENST00000416824.1 | LINC00957-201 | hsa-miR-4477b | chr7 | 44040983 | 44040989 | 7mer-m8 | 44040968 | 44040990 | 144 | -9.46 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000235314.1 | ENST00000441052.1 | LINC00957-202 | hsa-miR-4477b | chr7 | 44040983 | 44040989 | 7mer-m8 | 44040968 | 44040990 | 144 | -9.46 |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| Differentially expressed gene-miRNA network |
| Differentially expressed lncRNA-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for LINC00957 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000441052.1 | lncRNA |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1332825 | ENST00000441052.1 | chr7_44042047_+ | 2331 | -1287.30 | -1283.50 | -1304.30 |
| ADediting_1332826 | ENST00000441052.1 | chr7_44042053_+ | 2337 | -1283.60 | -1283.50 | -1304.30 |
| ADediting_1332827 | ENST00000441052.1 | chr7_44042054_+ | 2338 | -1283.50 | -1283.50 | -1304.30 |
| ADediting_1332828 | ENST00000441052.1 | chr7_44042059_+ | 2343 | -1282.80 | -1283.50 | -1304.30 |
| ADediting_1332829 | ENST00000441052.1 | chr7_44042075_+ | 2359 | -1286.90 | -1283.50 | -1304.30 |
| ADediting_1332830 | ENST00000441052.1 | chr7_44042076_+ | 2360 | -1283.10 | -1283.50 | -1304.30 |
| ADediting_1332831 | ENST00000441052.1 | chr7_44042084_+ | 2368 | -1289.70 | -1283.50 | -1304.30 |
| ADediting_1587511 | ENST00000441052.1 | chr7_44042092_+ | 2376 | -1282.70 | -1283.50 | -1304.30 |
| ADediting_1332832 | ENST00000441052.1 | chr7_44042097_+ | 2381 | -1282.80 | -1283.50 | -1304.30 |
| ADediting_1332833 | ENST00000441052.1 | chr7_44042098_+ | 2382 | -1290.10 | -1283.50 | -1304.30 |
| ADediting_1332834 | ENST00000441052.1 | chr7_44042121_+ | 2405 | -1283.50 | -1283.50 | -1304.30 |
| ADediting_1332835 | ENST00000441052.1 | chr7_44042130_+ | 2414 | -1283.60 | -1283.50 | -1304.30 |
| ADediting_1332836 | ENST00000441052.1 | chr7_44042131_+ | 2415 | -1283.50 | -1283.50 | -1304.30 |
| ADediting_1332837 | ENST00000441052.1 | chr7_44042142_+ | 2426 | -1283.50 | -1283.50 | -1304.30 |
| ADediting_1332838 | ENST00000441052.1 | chr7_44042145_+ | 2429 | -1283.60 | -1283.50 | -1304.30 |
| ADediting_1332839 | ENST00000441052.1 | chr7_44042151_+ | 2435 | -1283.50 | -1283.50 | -1304.30 |
| ADediting_1332840 | ENST00000441052.1 | chr7_44042154_+ | 2438 | -1283.60 | -1283.50 | -1304.30 |
| ADediting_1332841 | ENST00000441052.1 | chr7_44042156_+ | 2440 | -1283.60 | -1283.50 | -1304.30 |
| ADediting_1332842 | ENST00000441052.1 | chr7_44042168_+ | 2452 | -1283.10 | -1283.50 | -1304.30 |
| ADediting_1332843 | ENST00000441052.1 | chr7_44042186_+ | 2470 | -1289.00 | -1283.50 | -1304.30 |
| ADediting_1332844 | ENST00000441052.1 | chr7_44042192_+ | 2476 | -1282.80 | -1283.50 | -1304.30 |
| ADediting_1332845 | ENST00000441052.1 | chr7_44042196_+ | 2480 | -1283.50 | -1283.50 | -1304.30 |
| ADediting_1332846 | ENST00000441052.1 | chr7_44042200_+ | 2484 | -1287.50 | -1283.50 | -1304.30 |
| ADediting_1332847 | ENST00000441052.1 | chr7_44042209_+ | 2493 | -1282.60 | -1283.50 | -1304.30 |
| ADediting_1332848 | ENST00000441052.1 | chr7_44042213_+ | 2497 | -1282.80 | -1283.50 | -1304.30 |
| ADediting_1332849 | ENST00000441052.1 | chr7_44042222_+ | 2506 | -1282.50 | -1283.50 | -1304.30 |
| ADediting_1332850 | ENST00000441052.1 | chr7_44042227_+ | 2511 | -1283.00 | -1283.50 | -1304.30 |
| ADediting_1332851 | ENST00000441052.1 | chr7_44042228_+ | 2512 | -1283.50 | -1283.50 | -1304.30 |
| ADediting_1587512 | ENST00000441052.1 | chr7_44042239_+ | 2523 | -1282.80 | -1283.50 | -1304.30 |
| ADediting_1332852 | ENST00000441052.1 | chr7_44042302_+ | 2586 | -1283.80 | -1283.50 | -1304.30 |
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Relation with ADAR for LINC00957 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| TCX | ADediting_1332833 | chr7_44042098_+ | 0.869775616799367 | 0.0134982407023521 | 0.0048254638569785 | -0.228976205143317 | 1.00437247391205e-06 | 0.386903410398549 |
| TCX | ADediting_1332843 | chr7_44042186_+ | 0.564870659320023 | -0.0473692154849594 | 1.94862836637497e-05 | -0.34104156830487 | 0.000128743362007913 | 0.307583875028811 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 4.12191667680438e-06 | 0.258150483752631 | 0.183584421612856 | 0.0757249483800669 | 6.75952408500077e-43 | 0.676943068471787 |
| AC | 2.59388023992811e-11 | 0.405495678693717 | 6.00975081661532e-08 | 0.334453198831346 | 8.50262701878145e-38 | 0.697743045388307 |
| PCC | 2.30654089130541e-26 | 0.671168608433676 | 3.91232312670895e-30 | 0.706004107142601 | 9.78120602613299e-05 | 0.278144192760014 |
| CER | 2.25590056705624e-12 | 0.532765101977276 | 7.8469336146061e-09 | 0.449609443046671 | 0.0136963042338941 | 0.200901218556659 |
| TCX | 9.65781927165174e-08 | 0.418763070748902 | 6.98926004314842e-06 | 0.357711490682114 | 0.0300042484710687 | 0.177259842179795 |
| FP | 5.39582291829021e-06 | 0.333483710899402 | 0.0182917878700634 | 0.176714622344726 | 4.08742135398864e-05 | 0.30239429759309 |
| IFG | 1.92865741776315e-09 | 0.89302431451936 | 1.96939111349559e-06 | 0.795856622127022 | 0.116420067368852 | 0.322051081612752 |
| STG | 3.73641830378566e-06 | 0.480478448612005 | 0.00316087364221761 | 0.318395619967747 | 0.00016757193968733 | 0.399385841971845 |
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Relation with AD stages for LINC00957 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
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RelatedDrugs for LINC00957 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for LINC00957 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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