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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for SIN3B

check button Gene summary
Gene informationGene symbol

SIN3B

Gene ID

23309

Gene nameSIN3 transcription regulator family member B
Synonyms-
Cytomap

19p13.11

Type of geneprotein-coding
Descriptionpaired amphipathic helix protein Sin3bSIN3 homolog B, transcriptional regulatorSIN3 transcription regulator homolog Bhistone deacetylase complex subunit Sin3btranscriptional corepressor Sin3b
Modification date20200313
UniProtAcc

O75182,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for SIN3B

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_719638(16832267, +), ADediting_719639(16832291, +), ADediting_719640(16832359, +), ADediting_719641(16832363, +), ADediting_719642(16832778, +), ADediting_719643(16833356, +), ADediting_719644(16833362, +), ADediting_719645(16833378, +), ADediting_719646(16833379, +), ADediting_719647(16833384, +), ADediting_719648(16833416, +), ADediting_719649(16833417, +), ADediting_719650(16833422, +), ADediting_719651(16833430, +), ADediting_719652(16833436, +), ADediting_719653(16833455, +), ADediting_719654(16833456, +), ADediting_719655(16833470, +), ADediting_719656(16833472, +), ADediting_719657(16833473, +), ADediting_719658(16833479, +), ADediting_719659(16833485, +), ADediting_719660(16833489, +), ADediting_719661(16833503, +), ADediting_719662(16833511, +), ADediting_719663(16833512, +), ADediting_719664(16833521, +), ADediting_719665(16833528, +), ADediting_719666(16833553, +), ADediting_719667(16833619, +), ADediting_719668(16833743, +), ADediting_719669(16833746, +), ADediting_719670(16833788, +), ADediting_719671(16833810, +), ADediting_719672(16833823, +), ADediting_719673(16833824, +), ADediting_719674(16833853, +), ADediting_719675(16833863, +), ADediting_719676(16833889, +), ADediting_719677(16833906, +), ADediting_719678(16833927, +), ADediting_719679(16833949, +), ADediting_719680(16833986, +), ADediting_719681(16833987, +), ADediting_719682(16833999, +), ADediting_719683(16834021, +), ADediting_719684(16834983, +), ADediting_719685(16838695, +), ADediting_719686(16838741, +), ADediting_719687(16838746, +), ADediting_719688(16838749, +), ADediting_719689(16838765, +), ADediting_719690(16838772, +), ADediting_719691(16838775, +), ADediting_719692(16838811, +), ADediting_719693(16838814, +), ADediting_719694(16838854, +), ADediting_719695(16838857, +), ADediting_719696(16838863, +), ADediting_719697(16838888, +), ADediting_719698(16839148, +), ADediting_719699(16839203, +), ADediting_719700(16839220, +), ADediting_719701(16839221, +), ADediting_719702(16839229, +), ADediting_719703(16839230, +), ADediting_719704(16839236, +), ADediting_719705(16839242, +), ADediting_719706(16839749, +), ADediting_719707(16839765, +), ADediting_719708(16839766, +), ADediting_719709(16839771, +), ADediting_719710(16839774, +), ADediting_719711(16839782, +), ADediting_719712(16839787, +), ADediting_719713(16839788, +), ADediting_719714(16839796, +), ADediting_719715(16839812, +), ADediting_719716(16839821, +), ADediting_719717(16839840, +), ADediting_719718(16839841, +), ADediting_719719(16839846, +), ADediting_719720(16839861, +), ADediting_719721(16839866, +), ADediting_719722(16839867, +), ADediting_719723(16839870, +), ADediting_719724(16839902, +), ADediting_719725(16839919, +), ADediting_719726(16839924, +), ADediting_719727(16839925, +), ADediting_719728(16839936, +), ADediting_719729(16839937, +), ADediting_719730(16839938, +), ADediting_719731(16839945, +), ADediting_719732(16839949, +), ADediting_719733(16839961, +), ADediting_719734(16839986, +), ADediting_719735(16839988, +), ADediting_719736(16839991, +), ADediting_719737(16839992, +), ADediting_719738(16839999, +), ADediting_719739(16840004, +), ADediting_719740(16843199, +), ADediting_719741(16849809, +), ADediting_719742(16849835, +), ADediting_719743(16849836, +), ADediting_719744(16849849, +), ADediting_719745(16849862, +), ADediting_719746(16849863, +), ADediting_719747(16849877, +), ADediting_719748(16849881, +), ADediting_719749(16855466, +), ADediting_719750(16855482, +), ADediting_719751(16855488, +), ADediting_719752(16855493, +), ADediting_719753(16855496, +), ADediting_719754(16855506, +), ADediting_719755(16855511, +), ADediting_719756(16855524, +), ADediting_719757(16855525, +), ADediting_719758(16855535, +), ADediting_719759(16855556, +), ADediting_719760(16855559, +), ADediting_719761(16855560, +), ADediting_719762(16855561, +), ADediting_719763(16855565, +), ADediting_719764(16855570, +), ADediting_719765(16855571, +), ADediting_719766(16855574, +), ADediting_719767(16855590, +), ADediting_719768(16855600, +), ADediting_719769(16855601, +), ADediting_719770(16855610, +), ADediting_719771(16855627, +), ADediting_719772(16855633, +), ADediting_719773(16855642, +), ADediting_719774(16855646, +), ADediting_719775(16855666, +), ADediting_719776(16855673, +), ADediting_719777(16855676, +), ADediting_719778(16855713, +), ADediting_719779(16855794, +), ADediting_719780(16855801, +), ADediting_719781(16855807, +), ADediting_719782(16855836, +), ADediting_719783(16855846, +), ADediting_719784(16855850, +), ADediting_719785(16855853, +), ADediting_719786(16855880, +), ADediting_719787(16855901, +), ADediting_719788(16855906, +), ADediting_719789(16855907, +), ADediting_719790(16855926, +), ADediting_719791(16855928, +), ADediting_719792(16856002, +), ADediting_719793(16856012, +), ADediting_719794(16856595, +), ADediting_719795(16856636, +), ADediting_719796(16856646, +), ADediting_719797(16856651, +), ADediting_719798(16856652, +), ADediting_719799(16856658, +), ADediting_719800(16856665, +), ADediting_719801(16856671, +), ADediting_719802(16856672, +), ADediting_719803(16856701, +), ADediting_719804(16856711, +), ADediting_719805(16856724, +), ADediting_719806(16856737, +), ADediting_719807(16856738, +), ADediting_719808(16856746, +), ADediting_719809(16856752, +), ADediting_719810(16856755, +), ADediting_719811(16856757, +), ADediting_719812(16856781, +), ADediting_719813(16856793, +), ADediting_719814(16856801, +), ADediting_719815(16856806, +), ADediting_719816(16856807, +), ADediting_719817(16856810, +), ADediting_719818(16856824, +), ADediting_719819(16856841, +), ADediting_719820(16857933, +), ADediting_719821(16857946, +), ADediting_719822(16857970, +), ADediting_719823(16857976, +), ADediting_719824(16858129, +), ADediting_719825(16858154, +), ADediting_719826(16858695, +), ADediting_719827(16858760, +), ADediting_719828(16858785, +), ADediting_719829(16858794, +), ADediting_719830(16858829, +), ADediting_719831(16858875, +), ADediting_719832(16859083, +), ADediting_719833(16860970, +), ADediting_719834(16861377, +), ADediting_719835(16861380, +), ADediting_719836(16861400, +), ADediting_719837(16861425, +), ADediting_719838(16861426, +), ADediting_719839(16861501, +), ADediting_719840(16861624, +), ADediting_719841(16861659, +), ADediting_719842(16861684, +), ADediting_719843(16861704, +), ADediting_719844(16861879, +), ADediting_1553139(16832634, +), ADediting_1553140(16835057, +), ADediting_1553141(16838715, +), ADediting_1553142(16838727, +), ADediting_1553143(16838776, +), ADediting_1553144(16839133, +), ADediting_1553145(16839202, +), ADediting_1553146(16839856, +), ADediting_1553147(16855870, +), ADediting_1630891(16834991, +), ADediting_1630892(16838813, +), ADediting_1630893(16839839, +), ADediting_1630894(16861441, +),

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RNA editing positional annotations for SIN3B using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_719638chr19_16832267_+intronic
ADediting_719639chr19_16832291_+intronic
ADediting_719640chr19_16832359_+intronic
ADediting_719641chr19_16832363_+intronic
ADediting_719642chr19_16832778_+intronic
ADediting_719643chr19_16833356_+intronic
ADediting_719644chr19_16833362_+intronic
ADediting_719645chr19_16833378_+intronic
ADediting_719646chr19_16833379_+intronic
ADediting_719647chr19_16833384_+intronic
ADediting_719648chr19_16833416_+intronic
ADediting_719649chr19_16833417_+intronic
ADediting_719650chr19_16833422_+intronic
ADediting_719651chr19_16833430_+intronic
ADediting_719652chr19_16833436_+intronic
ADediting_719653chr19_16833455_+intronic
ADediting_719654chr19_16833456_+intronic
ADediting_719655chr19_16833470_+intronic
ADediting_719656chr19_16833472_+intronic
ADediting_719657chr19_16833473_+intronic
ADediting_719658chr19_16833479_+intronic
ADediting_719659chr19_16833485_+intronic
ADediting_719660chr19_16833489_+intronic
ADediting_719661chr19_16833503_+intronic
ADediting_719662chr19_16833511_+intronic
ADediting_719663chr19_16833512_+intronic
ADediting_719664chr19_16833521_+intronic
ADediting_719665chr19_16833528_+intronic
ADediting_719666chr19_16833553_+intronic
ADediting_719667chr19_16833619_+intronic
ADediting_719668chr19_16833743_+intronic
ADediting_719669chr19_16833746_+intronic
ADediting_719670chr19_16833788_+intronic
ADediting_719671chr19_16833810_+intronic
ADediting_719672chr19_16833823_+intronic
ADediting_719673chr19_16833824_+intronic
ADediting_719674chr19_16833853_+intronic
ADediting_719675chr19_16833863_+intronic
ADediting_719676chr19_16833889_+intronic
ADediting_719677chr19_16833906_+intronic
ADediting_719678chr19_16833927_+intronic
ADediting_719679chr19_16833949_+intronic
ADediting_719680chr19_16833986_+intronic
ADediting_719681chr19_16833987_+intronic
ADediting_719682chr19_16833999_+intronic
ADediting_719683chr19_16834021_+intronic
ADediting_719684chr19_16834983_+intronic
ADediting_719685chr19_16838695_+intronic
ADediting_719686chr19_16838741_+intronic
ADediting_719687chr19_16838746_+intronic
ADediting_719688chr19_16838749_+intronic
ADediting_719689chr19_16838765_+intronic
ADediting_719690chr19_16838772_+intronic
ADediting_719691chr19_16838775_+intronic
ADediting_719692chr19_16838811_+intronic
ADediting_719693chr19_16838814_+intronic
ADediting_719694chr19_16838854_+intronic
ADediting_719695chr19_16838857_+intronic
ADediting_719696chr19_16838863_+intronic
ADediting_719697chr19_16838888_+intronic
ADediting_719698chr19_16839148_+intronic
ADediting_719699chr19_16839203_+intronic
ADediting_719700chr19_16839220_+intronic
ADediting_719701chr19_16839221_+intronic
ADediting_719702chr19_16839229_+intronic
ADediting_719703chr19_16839230_+intronic
ADediting_719704chr19_16839236_+intronic
ADediting_719705chr19_16839242_+intronic
ADediting_719706chr19_16839749_+intronic
ADediting_719707chr19_16839765_+intronic
ADediting_719708chr19_16839766_+intronic
ADediting_719709chr19_16839771_+intronic
ADediting_719710chr19_16839774_+intronic
ADediting_719711chr19_16839782_+intronic
ADediting_719712chr19_16839787_+intronic
ADediting_719713chr19_16839788_+intronic
ADediting_719714chr19_16839796_+intronic
ADediting_719715chr19_16839812_+intronic
ADediting_719716chr19_16839821_+intronic
ADediting_719717chr19_16839840_+intronic
ADediting_719718chr19_16839841_+intronic
ADediting_719719chr19_16839846_+intronic
ADediting_719720chr19_16839861_+intronic
ADediting_719721chr19_16839866_+intronic
ADediting_719722chr19_16839867_+intronic
ADediting_719723chr19_16839870_+intronic
ADediting_719724chr19_16839902_+intronic
ADediting_719725chr19_16839919_+intronic
ADediting_719726chr19_16839924_+intronic
ADediting_719727chr19_16839925_+intronic
ADediting_719728chr19_16839936_+intronic
ADediting_719729chr19_16839937_+intronic
ADediting_719730chr19_16839938_+intronic
ADediting_719731chr19_16839945_+intronic
ADediting_719732chr19_16839949_+intronic
ADediting_719733chr19_16839961_+intronic
ADediting_719734chr19_16839986_+intronic
ADediting_719735chr19_16839988_+intronic
ADediting_719736chr19_16839991_+intronic
ADediting_719737chr19_16839992_+intronic
ADediting_719738chr19_16839999_+intronic
ADediting_719739chr19_16840004_+intronic
ADediting_719740chr19_16843199_+intronic
ADediting_719741chr19_16849809_+intronic
ADediting_719742chr19_16849835_+intronic
ADediting_719743chr19_16849836_+intronic
ADediting_719744chr19_16849849_+intronic
ADediting_719745chr19_16849862_+intronic
ADediting_719746chr19_16849863_+intronic
ADediting_719747chr19_16849877_+intronic
ADediting_719748chr19_16849881_+intronic
ADediting_719749chr19_16855466_+UTR3
ADediting_719750chr19_16855482_+UTR3
ADediting_719751chr19_16855488_+UTR3
ADediting_719752chr19_16855493_+UTR3
ADediting_719753chr19_16855496_+UTR3
ADediting_719754chr19_16855506_+UTR3
ADediting_719755chr19_16855511_+UTR3
ADediting_719756chr19_16855524_+UTR3
ADediting_719757chr19_16855525_+UTR3
ADediting_719758chr19_16855535_+UTR3
ADediting_719759chr19_16855556_+UTR3
ADediting_719760chr19_16855559_+UTR3
ADediting_719761chr19_16855560_+UTR3
ADediting_719762chr19_16855561_+UTR3
ADediting_719763chr19_16855565_+UTR3
ADediting_719764chr19_16855570_+UTR3
ADediting_719765chr19_16855571_+UTR3
ADediting_719766chr19_16855574_+UTR3
ADediting_719767chr19_16855590_+UTR3
ADediting_719768chr19_16855600_+UTR3
ADediting_719769chr19_16855601_+UTR3
ADediting_719770chr19_16855610_+UTR3
ADediting_719771chr19_16855627_+UTR3
ADediting_719772chr19_16855633_+UTR3
ADediting_719773chr19_16855642_+UTR3
ADediting_719774chr19_16855646_+UTR3
ADediting_719775chr19_16855666_+UTR3
ADediting_719776chr19_16855673_+UTR3
ADediting_719777chr19_16855676_+UTR3
ADediting_719778chr19_16855713_+UTR3
ADediting_719779chr19_16855794_+intronic
ADediting_719780chr19_16855801_+intronic
ADediting_719781chr19_16855807_+intronic
ADediting_719782chr19_16855836_+intronic
ADediting_719783chr19_16855846_+intronic
ADediting_719784chr19_16855850_+intronic
ADediting_719785chr19_16855853_+intronic
ADediting_719786chr19_16855880_+intronic
ADediting_719787chr19_16855901_+intronic
ADediting_719788chr19_16855906_+intronic
ADediting_719789chr19_16855907_+intronic
ADediting_719790chr19_16855926_+intronic
ADediting_719791chr19_16855928_+intronic
ADediting_719792chr19_16856002_+intronic
ADediting_719793chr19_16856012_+intronic
ADediting_719794chr19_16856595_+intronic
ADediting_719795chr19_16856636_+intronic
ADediting_719796chr19_16856646_+intronic
ADediting_719797chr19_16856651_+intronic
ADediting_719798chr19_16856652_+intronic
ADediting_719799chr19_16856658_+intronic
ADediting_719800chr19_16856665_+intronic
ADediting_719801chr19_16856671_+intronic
ADediting_719802chr19_16856672_+intronic
ADediting_719803chr19_16856701_+intronic
ADediting_719804chr19_16856711_+intronic
ADediting_719805chr19_16856724_+intronic
ADediting_719806chr19_16856737_+intronic
ADediting_719807chr19_16856738_+intronic
ADediting_719808chr19_16856746_+intronic
ADediting_719809chr19_16856752_+intronic
ADediting_719810chr19_16856755_+intronic
ADediting_719811chr19_16856757_+intronic
ADediting_719812chr19_16856781_+intronic
ADediting_719813chr19_16856793_+intronic
ADediting_719814chr19_16856801_+intronic
ADediting_719815chr19_16856806_+intronic
ADediting_719816chr19_16856807_+intronic
ADediting_719817chr19_16856810_+intronic
ADediting_719818chr19_16856824_+intronic
ADediting_719819chr19_16856841_+intronic
ADediting_719820chr19_16857933_+intronic
ADediting_719821chr19_16857946_+intronic
ADediting_719822chr19_16857970_+intronic
ADediting_719823chr19_16857976_+intronic
ADediting_719824chr19_16858129_+intronic
ADediting_719825chr19_16858154_+intronic
ADediting_719826chr19_16858695_+intronic
ADediting_719827chr19_16858760_+intronic
ADediting_719828chr19_16858785_+intronic
ADediting_719829chr19_16858794_+intronic
ADediting_719830chr19_16858829_+intronic
ADediting_719831chr19_16858875_+intronic
ADediting_719832chr19_16859083_+intronic
ADediting_719833chr19_16860970_+intronic
ADediting_719834chr19_16861377_+intronic
ADediting_719835chr19_16861380_+intronic
ADediting_719836chr19_16861400_+intronic
ADediting_719837chr19_16861425_+intronic
ADediting_719838chr19_16861426_+intronic
ADediting_719839chr19_16861501_+intronic
ADediting_719840chr19_16861624_+intronic
ADediting_719841chr19_16861659_+intronic
ADediting_719842chr19_16861684_+intronic
ADediting_719843chr19_16861704_+intronic
ADediting_719844chr19_16861879_+intronic
ADediting_1553139chr19_16832634_+intronic
ADediting_1553140chr19_16835057_+intronic
ADediting_1553141chr19_16838715_+intronic
ADediting_1553142chr19_16838727_+intronic
ADediting_1553143chr19_16838776_+intronic
ADediting_1553144chr19_16839133_+intronic
ADediting_1553145chr19_16839202_+intronic
ADediting_1553146chr19_16839856_+intronic
ADediting_1553147chr19_16855870_+intronic
ADediting_1630891chr19_16834991_+intronic
ADediting_1630892chr19_16838813_+intronic
ADediting_1630893chr19_16839839_+intronic
ADediting_1630894chr19_16861441_+intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_719638chr19_16832267_+SINEAluName=AluSz
ADediting_719639chr19_16832291_+SINEAluName=AluSz
ADediting_719640chr19_16832359_+SINEAluName=AluSz
ADediting_719641chr19_16832363_+SINEAluName=AluSz
ADediting_719642chr19_16832778_+SINEAluName=AluJr
ADediting_719643chr19_16833356_+SINEAluName=AluSg
ADediting_719644chr19_16833362_+SINEAluName=AluSg
ADediting_719645chr19_16833378_+SINEAluName=AluSg
ADediting_719646chr19_16833379_+SINEAluName=AluSg
ADediting_719647chr19_16833384_+SINEAluName=AluSg
ADediting_719648chr19_16833416_+SINEAluName=AluSg
ADediting_719649chr19_16833417_+SINEAluName=AluSg
ADediting_719650chr19_16833422_+SINEAluName=AluSg
ADediting_719651chr19_16833430_+SINEAluName=AluSg
ADediting_719652chr19_16833436_+SINEAluName=AluSg
ADediting_719653chr19_16833455_+SINEAluName=AluSg
ADediting_719654chr19_16833456_+SINEAluName=AluSg
ADediting_719655chr19_16833470_+SINEAluName=AluSg
ADediting_719656chr19_16833472_+SINEAluName=AluSg
ADediting_719657chr19_16833473_+SINEAluName=AluSg
ADediting_719658chr19_16833479_+SINEAluName=AluSg
ADediting_719659chr19_16833485_+SINEAluName=AluSg
ADediting_719660chr19_16833489_+SINEAluName=AluSg
ADediting_719661chr19_16833503_+SINEAluName=AluSg
ADediting_719662chr19_16833511_+SINEAluName=AluSg
ADediting_719663chr19_16833512_+SINEAluName=AluSg
ADediting_719664chr19_16833521_+SINEAluName=AluSg
ADediting_719665chr19_16833528_+SINEAluName=AluSg
ADediting_719666chr19_16833553_+SINEAluName=AluSg
ADediting_719667chr19_16833619_+SINEAluName=AluSg
ADediting_719668chr19_16833743_+SINEAluName=AluSx3
ADediting_719669chr19_16833746_+SINEAluName=AluSx3
ADediting_719670chr19_16833788_+SINEAluName=AluSx3
ADediting_719671chr19_16833810_+SINEAluName=AluSx3
ADediting_719672chr19_16833823_+SINEAluName=AluSx3
ADediting_719673chr19_16833824_+SINEAluName=AluSx3
ADediting_719674chr19_16833853_+SINEAluName=AluSx3
ADediting_719675chr19_16833863_+SINEAluName=AluSx3
ADediting_719676chr19_16833889_+SINEAluName=AluSx3
ADediting_719677chr19_16833906_+SINEAluName=AluSx3
ADediting_719678chr19_16833927_+SINEAluName=AluSx3
ADediting_719679chr19_16833949_+SINEAluName=AluSx3
ADediting_719680chr19_16833986_+SINEAluName=AluSx3
ADediting_719681chr19_16833987_+SINEAluName=AluSx3
ADediting_719682chr19_16833999_+SINEAluName=AluSx3
ADediting_719683chr19_16834021_+SINEAluName=AluSx3
ADediting_719684chr19_16834983_+SINEAluName=AluSp
ADediting_719685chr19_16838695_+SINEAluName=AluSx3
ADediting_719686chr19_16838741_+SINEAluName=AluSx3
ADediting_719687chr19_16838746_+SINEAluName=AluSx3
ADediting_719688chr19_16838749_+SINEAluName=AluSx3
ADediting_719689chr19_16838765_+SINEAluName=AluSx3
ADediting_719690chr19_16838772_+SINEAluName=AluSx3
ADediting_719691chr19_16838775_+SINEAluName=AluSx3
ADediting_719692chr19_16838811_+SINEAluName=AluSx3
ADediting_719693chr19_16838814_+SINEAluName=AluSx3
ADediting_719694chr19_16838854_+SINEAluName=AluSx3
ADediting_719695chr19_16838857_+SINEAluName=AluSx3
ADediting_719696chr19_16838863_+SINEAluName=AluSx3
ADediting_719697chr19_16838888_+SINEAluName=AluSx3
ADediting_719698chr19_16839148_+SINEAluName=AluSq
ADediting_719699chr19_16839203_+SINEAluName=AluSq
ADediting_719700chr19_16839220_+SINEAluName=AluSq
ADediting_719701chr19_16839221_+SINEAluName=AluSq
ADediting_719702chr19_16839229_+SINEAluName=AluSq
ADediting_719703chr19_16839230_+SINEAluName=AluSq
ADediting_719704chr19_16839236_+SINEAluName=AluSq
ADediting_719705chr19_16839242_+SINEAluName=AluSq
ADediting_719706chr19_16839749_+SINEAluName=AluSz
ADediting_719707chr19_16839765_+SINEAluName=AluSz
ADediting_719708chr19_16839766_+SINEAluName=AluSz
ADediting_719709chr19_16839771_+SINEAluName=AluSz
ADediting_719710chr19_16839774_+SINEAluName=AluSz
ADediting_719711chr19_16839782_+SINEAluName=AluSz
ADediting_719712chr19_16839787_+SINEAluName=AluSz
ADediting_719713chr19_16839788_+SINEAluName=AluSz
ADediting_719714chr19_16839796_+SINEAluName=AluSz
ADediting_719715chr19_16839812_+SINEAluName=AluSz
ADediting_719716chr19_16839821_+SINEAluName=AluSz
ADediting_719717chr19_16839840_+SINEAluName=AluSz
ADediting_719718chr19_16839841_+SINEAluName=AluSz
ADediting_719719chr19_16839846_+SINEAluName=AluSz
ADediting_719720chr19_16839861_+SINEAluName=AluSz
ADediting_719721chr19_16839866_+SINEAluName=AluSz
ADediting_719722chr19_16839867_+SINEAluName=AluSz
ADediting_719723chr19_16839870_+SINEAluName=AluSz
ADediting_719724chr19_16839902_+SINEAluName=AluSz
ADediting_719725chr19_16839919_+SINEAluName=AluSz
ADediting_719726chr19_16839924_+SINEAluName=AluSz
ADediting_719727chr19_16839925_+SINEAluName=AluSz
ADediting_719728chr19_16839936_+SINEAluName=AluSz
ADediting_719729chr19_16839937_+SINEAluName=AluSz
ADediting_719730chr19_16839938_+SINEAluName=AluSz
ADediting_719731chr19_16839945_+SINEAluName=AluSz
ADediting_719732chr19_16839949_+SINEAluName=AluSz
ADediting_719733chr19_16839961_+SINEAluName=AluSz
ADediting_719734chr19_16839986_+SINEAluName=AluSz
ADediting_719735chr19_16839988_+SINEAluName=AluSz
ADediting_719736chr19_16839991_+SINEAluName=AluSz
ADediting_719737chr19_16839992_+SINEAluName=AluSz
ADediting_719738chr19_16839999_+SINEAluName=AluSz
ADediting_719739chr19_16840004_+SINEAluName=AluSz
ADediting_719740chr19_16843199_+SINEAluName=AluSx3
ADediting_719741chr19_16849809_+SINEAluName=AluSx
ADediting_719742chr19_16849835_+SINEAluName=AluSx
ADediting_719743chr19_16849836_+SINEAluName=AluSx
ADediting_719744chr19_16849849_+SINEAluName=AluSx
ADediting_719745chr19_16849862_+SINEAluName=AluSx
ADediting_719746chr19_16849863_+SINEAluName=AluSx
ADediting_719747chr19_16849877_+SINEAluName=AluSx
ADediting_719748chr19_16849881_+SINEAluName=AluSx
ADediting_719749chr19_16855466_+SINEAluName=AluSq2
ADediting_719750chr19_16855482_+SINEAluName=AluSq2
ADediting_719751chr19_16855488_+SINEAluName=AluSq2
ADediting_719752chr19_16855493_+SINEAluName=AluSq2
ADediting_719753chr19_16855496_+SINEAluName=AluSq2
ADediting_719754chr19_16855506_+SINEAluName=AluSq2
ADediting_719755chr19_16855511_+SINEAluName=AluSq2
ADediting_719756chr19_16855524_+SINEAluName=AluSq2
ADediting_719757chr19_16855525_+SINEAluName=AluSq2
ADediting_719758chr19_16855535_+SINEAluName=AluSq2
ADediting_719759chr19_16855556_+SINEAluName=AluSq2
ADediting_719760chr19_16855559_+SINEAluName=AluSq2
ADediting_719761chr19_16855560_+SINEAluName=AluSq2
ADediting_719762chr19_16855561_+SINEAluName=AluSq2
ADediting_719763chr19_16855565_+SINEAluName=AluSq2
ADediting_719764chr19_16855570_+SINEAluName=AluSq2
ADediting_719765chr19_16855571_+SINEAluName=AluSq2
ADediting_719766chr19_16855574_+SINEAluName=AluSq2
ADediting_719767chr19_16855590_+SINEAluName=AluSq2
ADediting_719768chr19_16855600_+SINEAluName=AluSq2
ADediting_719769chr19_16855601_+SINEAluName=AluSq2
ADediting_719770chr19_16855610_+SINEAluName=AluSq2
ADediting_719771chr19_16855627_+SINEAluName=AluSq2
ADediting_719772chr19_16855633_+SINEAluName=AluSq2
ADediting_719773chr19_16855642_+SINEAluName=AluSq2
ADediting_719774chr19_16855646_+SINEAluName=AluSq2
ADediting_719775chr19_16855666_+SINEAluName=AluSq2
ADediting_719776chr19_16855673_+SINEAluName=AluSq2
ADediting_719777chr19_16855676_+SINEAluName=AluSq2
ADediting_719778chr19_16855713_+SINEAluName=AluSq2
ADediting_719779chr19_16855794_+SINEAluName=AluJb
ADediting_719780chr19_16855801_+SINEAluName=AluJb
ADediting_719781chr19_16855807_+SINEAluName=AluJb
ADediting_719782chr19_16855836_+SINEAluName=AluJb
ADediting_719783chr19_16855846_+SINEAluName=AluJb
ADediting_719784chr19_16855850_+SINEAluName=AluJb
ADediting_719785chr19_16855853_+SINEAluName=AluJb
ADediting_719786chr19_16855880_+SINEAluName=AluJb
ADediting_719787chr19_16855901_+SINEAluName=AluJb
ADediting_719788chr19_16855906_+SINEAluName=AluJb
ADediting_719789chr19_16855907_+SINEAluName=AluJb
ADediting_719790chr19_16855926_+SINEAluName=AluJb
ADediting_719791chr19_16855928_+SINEAluName=AluJb
ADediting_719792chr19_16856002_+SINEAluName=AluJb
ADediting_719793chr19_16856012_+SINEAluName=AluJb
ADediting_719794chr19_16856595_+SINEAluName=AluSz6
ADediting_719795chr19_16856636_+SINEAluName=AluSz6
ADediting_719796chr19_16856646_+SINEAluName=AluSz6
ADediting_719797chr19_16856651_+SINEAluName=AluSz6
ADediting_719798chr19_16856652_+SINEAluName=AluSz6
ADediting_719799chr19_16856658_+SINEAluName=AluSz6
ADediting_719800chr19_16856665_+SINEAluName=AluSz6
ADediting_719801chr19_16856671_+SINEAluName=AluSz6
ADediting_719802chr19_16856672_+SINEAluName=AluSz6
ADediting_719803chr19_16856701_+SINEAluName=AluSz6
ADediting_719804chr19_16856711_+SINEAluName=AluSz6
ADediting_719805chr19_16856724_+SINEAluName=AluSz6
ADediting_719806chr19_16856737_+SINEAluName=AluSz6
ADediting_719807chr19_16856738_+SINEAluName=AluSz6
ADediting_719808chr19_16856746_+SINEAluName=AluSz6
ADediting_719809chr19_16856752_+SINEAluName=AluSz6
ADediting_719810chr19_16856755_+SINEAluName=AluSz6
ADediting_719811chr19_16856757_+SINEAluName=AluSz6
ADediting_719812chr19_16856781_+SINEAluName=AluSz6
ADediting_719813chr19_16856793_+SINEAluName=AluSz6
ADediting_719814chr19_16856801_+SINEAluName=AluSz6
ADediting_719815chr19_16856806_+SINEAluName=AluSz6
ADediting_719816chr19_16856807_+SINEAluName=AluSz6
ADediting_719817chr19_16856810_+SINEAluName=AluSz6
ADediting_719818chr19_16856824_+SINEAluName=AluSz6
ADediting_719819chr19_16856841_+SINEAluName=AluSz6
ADediting_719820chr19_16857933_+SINEAluName=AluSx1
ADediting_719821chr19_16857946_+SINEAluName=AluSx1
ADediting_719822chr19_16857970_+SINEAluName=AluSx1
ADediting_719823chr19_16857976_+SINEAluName=AluSx1
ADediting_719824chr19_16858129_+SINEAluName=AluSx1
ADediting_719825chr19_16858154_+SINEAluName=AluSx1
ADediting_719826chr19_16858695_+SINEAluName=AluSx
ADediting_719827chr19_16858760_+SINEAluName=AluSx
ADediting_719828chr19_16858785_+SINEAluName=AluSx
ADediting_719829chr19_16858794_+SINEAluName=AluSx
ADediting_719830chr19_16858829_+SINEAluName=AluSx
ADediting_719831chr19_16858875_+SINEAluName=AluSx
ADediting_719832chr19_16859083_+SINEAluName=AluJb
ADediting_719833chr19_16860970_+SINEAluName=FLAM_C
ADediting_719834chr19_16861377_+SINEAluName=AluJr
ADediting_719835chr19_16861380_+SINEAluName=AluJr
ADediting_719836chr19_16861400_+SINEAluName=AluJr
ADediting_719837chr19_16861425_+SINEAluName=AluJr
ADediting_719838chr19_16861426_+SINEAluName=AluJr
ADediting_719839chr19_16861501_+SINEAluName=AluSq2
ADediting_719840chr19_16861624_+SINEAluName=AluSq2
ADediting_719841chr19_16861659_+SINEAluName=AluSq2
ADediting_719842chr19_16861684_+SINEAluName=AluSq2
ADediting_719843chr19_16861704_+SINEAluName=AluSq2
ADediting_719844chr19_16861879_+SINEAluName=AluJr
ADediting_1553139chr19_16832634_+SINEAluName=AluJr
ADediting_1553140chr19_16835057_+SINEAluName=AluSp
ADediting_1553141chr19_16838715_+SINEAluName=AluSx3
ADediting_1553142chr19_16838727_+SINEAluName=AluSx3
ADediting_1553143chr19_16838776_+SINEAluName=AluSx3
ADediting_1553144chr19_16839133_+SINEAluName=AluSq
ADediting_1553145chr19_16839202_+SINEAluName=AluSq
ADediting_1553146chr19_16839856_+SINEAluName=AluSz
ADediting_1553147chr19_16855870_+SINEAluName=AluJb
ADediting_1630891chr19_16834991_+SINEAluName=AluSp
ADediting_1630892chr19_16838813_+SINEAluName=AluSx3
ADediting_1630893chr19_16839839_+SINEAluName=AluSz
ADediting_1630894chr19_16861441_+SINEAluName=AluJr

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RNA A-to-I editing events in the alternative splicing sites for SIN3B

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SIN3B

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for SIN3B

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for SIN3B

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_719750chr19_16855482_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-10392-3pchr1916855480168554878mer-1a1685546316855487144-22.69
ADediting_719751chr19_16855488_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4707-5pchr1916855483168554897mer-m81685546816855490142-26.95
ADediting_719751chr19_16855488_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-6802-3pchr1916855486168554927mer-m81685547216855493159-25.94
ADediting_719752chr19_16855493_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-1224-3pchr1916855487168554937mer-m81685547516855494156-26.33
ADediting_719753chr19_16855496_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-572chr1916855491168554977mer-m81685548016855498152-29.33
ADediting_719754chr19_16855506_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4645-5pchr1916855499168555057mer-m81685548816855506145-14.77
ADediting_719754chr19_16855506_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4673chr1916855499168555057mer-m81685548516855506141-21.94
ADediting_719757chr19_16855525_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-214-5pchr1916855520168555267mer-m81685550616855527167-21.86
ADediting_719757chr19_16855525_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4421chr1916855519168555257mer-m81685550516855526140-16.1
ADediting_719757chr19_16855525_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4650-5pchr1916855523168555297mer-m81685551216855530161-22.5
ADediting_719757chr19_16855525_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-5699-3pchr1916855519168555257mer-m81685550516855526151-19.28
ADediting_719757chr19_16855525_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-6735-3pchr1916855521168555277mer-m81685550216855528154-33.66
ADediting_719758chr19_16855535_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-3190-5pchr1916855528168555347mer-m81685551616855535154-23.55
ADediting_719759chr19_16855556_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-374b-3pchr1916855553168555608mer-1a1685553816855560155-14.25
ADediting_719759chr19_16855556_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4756-3pchr1916855549168555557mer-m81685553416855556155-20.78
ADediting_719760chr19_16855559_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-222-5pchr1916855553168555608mer-1a1685554016855560154-15.5
ADediting_719760chr19_16855559_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-30a-3pchr1916855555168555628mer-1a1685553816855562154-12.82
ADediting_719760chr19_16855559_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-30d-3pchr1916855555168555628mer-1a1685554016855562153-12.1
ADediting_719760chr19_16855559_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-30e-3pchr1916855555168555628mer-1a1685553816855562154-13.76
ADediting_719760chr19_16855559_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-936chr1916855552168555598mer-1a1685553616855559152-24.26
ADediting_719761chr19_16855560_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-325chr1916855553168555608mer-1a1685553816855560153-15.22
ADediting_719762chr19_16855561_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-630chr1916855559168555668mer-1a1685554616855566158-15.61
ADediting_719763chr19_16855565_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-153-5pchr1916855558168555647mer-m81685554316855565155-10.34
ADediting_719763chr19_16855565_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-3680-3pchr1916855562168555698mer-1a1685554716855569140-14.24
ADediting_719764chr19_16855570_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-6844chr1916855564168555707mer-m81685555016855571155-7.49
ADediting_719767chr19_16855590_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4258chr1916855585168555917mer-m81685557616855592156-29
ADediting_719767chr19_16855590_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4707-3pchr1916855586168555927mer-m81685557116855593156-31.43
ADediting_719768chr19_16855600_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-513a-5pchr1916855594168556007mer-m81685558416855601144-17.68
ADediting_719768chr19_16855600_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-638chr1916855599168556057mer-1a1685558116855605159-34.46
ADediting_719769chr19_16855601_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-8052chr1916855599168556057mer-1a1685558516855605145-22.32
ADediting_719770chr19_16855610_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-1207-3pchr1916855603168556097mer-m81685559316855610140-12.56
ADediting_719770chr19_16855610_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-646chr1916855605168556117mer-m81685559416855612145-16.24
ADediting_719772chr19_16855633_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4431chr1916855629168556357mer-m81685561516855636140-17.94
ADediting_719773chr19_16855642_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-10400-3pchr1916855639168556457mer-m81685562716855646141-23.04
ADediting_719773chr19_16855642_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4437chr1916855638168556458mer-1a1685562516855645146-19.59
ADediting_719773chr19_16855642_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4674chr1916855639168556457mer-m81685562716855646148-24.84
ADediting_719775chr19_16855666_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-324-3pchr1916855659168556657mer-m81685564416855666145-25.24
ADediting_719775chr19_16855666_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4690-3pchr1916855663168556708mer-1a1685565116855670165-30.74
ADediting_719775chr19_16855666_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-5685chr1916855663168556708mer-1a1685564716855670150-22.78
ADediting_719777chr19_16855676_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4634chr1916855673168556808mer-1a1685566016855680146-21.85

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_719749chr19_16855466_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-5089-5pchr1916855464168554707mer-m81685545116855471150-14.91
ADediting_719750chr19_16855482_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-150-5pchr1916855476168554827mer-m81685546216855483140-15.8
ADediting_719750chr19_16855482_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-6778-3pchr1916855478168554847mer-m81685546516855485143-13.97
ADediting_719752chr19_16855493_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-1178-3pchr1916855489168554957mer-m81685547516855496153-23.85
ADediting_719752chr19_16855493_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-767-3pchr1916855490168554978mer-1a1685547916855497144-24.62
ADediting_719753chr19_16855496_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-1178-3pchr1916855489168554957mer-m81685547516855496153-23.85
ADediting_719753chr19_16855496_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4686chr1916855492168554987mer-m81685547716855499146-18.13
ADediting_719753chr19_16855496_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-767-3pchr1916855490168554978mer-1a1685547916855497144-24.62
ADediting_719754chr19_16855506_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-6790-3pchr1916855504168555107mer-1a1685548816855510141-25.56
ADediting_719756chr19_16855524_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-6818-3pchr1916855518168555247mer-1a1685550316855524150-20.61
ADediting_719758chr19_16855535_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4716-5pchr1916855533168555397mer-m81685551916855540140-10.98
ADediting_719758chr19_16855535_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4781-3pchr1916855531168555377mer-m81685552016855538144-13.86
ADediting_719759chr19_16855556_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-6832-5pchr1916855550168555567mer-m81685553716855557146-16.01
ADediting_719764chr19_16855570_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4735-5pchr1916855568168555747mer-m81685555416855575140-5.48
ADediting_719765chr19_16855571_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4735-5pchr1916855568168555747mer-m81685555416855575140-5.48
ADediting_719766chr19_16855574_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4735-5pchr1916855568168555747mer-m81685555416855575140-5.48
ADediting_719767chr19_16855590_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4715-3pchr1916855583168555897mer-m81685556816855590143-17.21
ADediting_719767chr19_16855590_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-4763-5pchr1916855586168555927mer-m81685557016855593153-29.07
ADediting_719767chr19_16855590_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-6720-3pchr1916855588168555947mer-m81685557416855595147-22.55
ADediting_719768chr19_16855600_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-10399-5pchr1916855595168556017mer-m81685558316855602145-12.94
ADediting_719768chr19_16855600_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-6504-3pchr1916855595168556017mer-m81685558116855602148-14.15
ADediting_719768chr19_16855600_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-7151-3pchr1916855593168556008mer-1a1685558016855600140-12.35
ADediting_719769chr19_16855601_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-10399-5pchr1916855595168556017mer-m81685558316855602145-12.94
ADediting_719769chr19_16855601_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-5089-5pchr1916855599168556057mer-m81685558616855606144-13.5
ADediting_719769chr19_16855601_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-6504-3pchr1916855595168556017mer-m81685558116855602148-14.15
ADediting_719770chr19_16855610_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-562chr1916855606168556127mer-m81685559416855613150-12.74
ADediting_719770chr19_16855610_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-5697chr1916855607168556137mer-m81685559216855614149-18.32
ADediting_719771chr19_16855627_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-1976chr1916855624168556318mer-1a1685561116855631149-21.37
ADediting_719771chr19_16855627_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-6747-3pchr1916855622168556298mer-1a1685560816855629150-24.11
ADediting_719773chr19_16855642_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-498-5pchr1916855635168556417mer-m81685562016855642142-9.71
ADediting_719774chr19_16855646_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-1343-3pchr1916855642168556487mer-m81685562616855649150-24.17
ADediting_719774chr19_16855646_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-6742-3pchr1916855641168556488mer-1a1685562916855648145-14.93
ADediting_719774chr19_16855646_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-6783-3pchr1916855642168556487mer-m81685562916855649146-17.13
ADediting_719778chr19_16855713_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-1264chr1916855711168557177mer-m81685569516855718146-14.33
ADediting_719778chr19_16855713_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-431-5pchr1916855709168557157mer-m81685569416855716145-20.43

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-589-3pchr1916854760168547678mer-1a1685474316854767155-24.27
ADediting_1535951chr14_100874558_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-337-3pchr1916855341168553477mer-m81685532616855348159-18.39
ADediting_1535953chr14_101045971_+ENSG00000127511.9ENST00000596802.5SIN3B-209hsa-miR-381-3pchr1916854870168548767mer-m81685485716854877141-9.62

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000127511.9ENST00000248054.9SIN3B-201hsa-miR-589-3pchr1916880257168802637mer-m81688023916880264149-17.11
ADediting_1337757chr7_5495852_-ENSG00000127511.9ENST00000379803.5SIN3B-202hsa-miR-589-3pchr1916880257168802637mer-m81688023916880264149-17.11
ADediting_496066chr15_66496985_-ENSG00000127511.9ENST00000248054.9SIN3B-201hsa-miR-4512chr1916879267168792737mer-m81687925416879274148-21.01
ADediting_496066chr15_66496985_-ENSG00000127511.9ENST00000379803.5SIN3B-202hsa-miR-4512chr1916879267168792737mer-m81687925416879274148-21.01

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for SIN3B

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000596802.5protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_719749ENST00000596802.5chr19_16855466_+2277-899.10-899.10-927.30
ADediting_719750ENST00000596802.5chr19_16855482_+2293-900.90-899.10-927.30
ADediting_719751ENST00000596802.5chr19_16855488_+2299-905.10-899.10-927.30
ADediting_719752ENST00000596802.5chr19_16855493_+2304-900.20-899.10-927.30
ADediting_719753ENST00000596802.5chr19_16855496_+2307-901.80-899.10-927.30
ADediting_719754ENST00000596802.5chr19_16855506_+2317-900.60-899.10-927.30
ADediting_719755ENST00000596802.5chr19_16855511_+2322-899.10-899.10-927.30
ADediting_719756ENST00000596802.5chr19_16855524_+2335-899.10-899.10-927.30
ADediting_719757ENST00000596802.5chr19_16855525_+2336-899.10-899.10-927.30
ADediting_719758ENST00000596802.5chr19_16855535_+2346-898.80-899.10-927.30
ADediting_719759ENST00000596802.5chr19_16855556_+2367-900.70-899.10-927.30
ADediting_719760ENST00000596802.5chr19_16855559_+2370-899.20-899.10-927.30
ADediting_719761ENST00000596802.5chr19_16855560_+2371-899.10-899.10-927.30
ADediting_719762ENST00000596802.5chr19_16855561_+2372-899.20-899.10-927.30
ADediting_719763ENST00000596802.5chr19_16855565_+2376-899.40-899.10-927.30
ADediting_719764ENST00000596802.5chr19_16855570_+2381-899.10-899.10-927.30
ADediting_719765ENST00000596802.5chr19_16855571_+2382-901.60-899.10-927.30
ADediting_719766ENST00000596802.5chr19_16855574_+2385-902.00-899.10-927.30
ADediting_719767ENST00000596802.5chr19_16855590_+2401-898.40-899.10-927.30
ADediting_719768ENST00000596802.5chr19_16855600_+2411-899.10-899.10-927.30
ADediting_719769ENST00000596802.5chr19_16855601_+2412-899.10-899.10-927.30
ADediting_719770ENST00000596802.5chr19_16855610_+2421-899.10-899.10-927.30
ADediting_719771ENST00000596802.5chr19_16855627_+2438-898.40-899.10-927.30
ADediting_719772ENST00000596802.5chr19_16855633_+2444-902.70-899.10-927.30
ADediting_719773ENST00000596802.5chr19_16855642_+2453-899.40-899.10-927.30
ADediting_719774ENST00000596802.5chr19_16855646_+2457-898.40-899.10-927.30
ADediting_719775ENST00000596802.5chr19_16855666_+2477-900.90-899.10-927.30
ADediting_719776ENST00000596802.5chr19_16855673_+2484-899.10-899.10-927.30
ADediting_719777ENST00000596802.5chr19_16855676_+2487-898.40-899.10-927.30
ADediting_719778ENST00000596802.5chr19_16855713_+2524-898.80-899.10-927.30

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for SIN3B

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_719714chr19_16839796_+0.3447389181502390.05384206284035930.287565300904365-0.06059074415546151.10172018651275e-080.317400913978044
DLPFCADediting_719770chr19_16855610_+0.001444954973252420.180170248694410.0201036397897590.1319727042014073.70655812416133e-090.32698467460237
DLPFCADediting_719773chr19_16855642_+3.98979544030639e-080.3056256141891892.34669929146995e-050.2377032011227981.76840986357503e-060.267504404118352
DLPFCADediting_719774chr19_16855646_+1.05780723483325e-070.2963446133257585.43758152014236e-090.3236512303373280.0001055402439781170.218443596891672
DLPFCADediting_719777chr19_16855676_+2.36416109876402e-050.2376121285428211.84066044552109e-080.3127659698339830.0003435220414920080.202048646117563
DLPFCADediting_719791chr19_16855928_+2.69096236260785e-080.3092844474399540.0002376185842226480.207305447078890.00794951879011510.150497231894314
TCXADediting_719791chr19_16855928_+0.0008131618452557120.2705324951510312.96402044770327e-050.3339389843280530.533239293763088-0.0512687710069226
TCXADediting_719793chr19_16856012_+0.006172306173043440.2226451505828450.0001440290609755950.305465902008750.236871201582346-0.0971628774138083
DLPFCADediting_719798chr19_16856652_+9.3724747295735e-060.2487123672155432.16850396900324e-100.3505061112448210.04545158248260570.113708584941695
DLPFCADediting_719800chr19_16856665_+1.8709574805859e-050.2404693105529731.06404025176941e-090.3375701359968870.01225219312099620.142114203682986
DLPFCADediting_719809chr19_16856752_+2.95875035872346e-060.2618579065671153.40701318800704e-080.3070985773782460.1002136967782880.0935356949008427
DLPFCADediting_719816chr19_16856807_+3.15996357082072e-080.3077979170162261.42631874570274e-130.4035769971114460.001511523068527320.179443904722104
DLPFCADediting_719818chr19_16856824_+1.33086055014981e-100.3543609329388861.2348905845245e-160.4470232483595950.004498391836056810.160950228917574
TCXADediting_719818chr19_16856824_+0.001188502188435990.2622239357857391.6562229411719e-050.3437488889484360.183904750865507-0.109086819289109

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC2.23613892249675e-300.5893279235543321.41368618540159e-210.5061940710202461.93123144398374e-360.635289980515165
AC1.44713346938037e-500.7712639946587511.08680149782326e-480.7619245807898816.71807581204948e-100.377723824127424
PCC1.7616443818725e-460.8140787430352071.07404257542252e-420.7938735628438570.0001563018334822630.270238058627946
CER7.37501483763836e-310.7714500487162144.48471538665694e-270.7381133371678821.2539720144118e-050.348324416440769
TCX1.89204917174626e-430.8520619778517783.17654060659204e-230.6980360020338310.1128077728918220.130009185421568
FP4.47906462495351e-370.7760583063668717.43414929231484e-130.5039658366293123.70760688333467e-100.447708211691024
IFG8.32753921146456e-090.8776884893655731.43430687969661e-070.8407311978516990.05394455541277390.390001590821551
PG2.02744402057393e-100.444722288376473.69928897848915e-140.5179594293468770.04665223132244590.146074432026626
STG1.89200997454507e-200.8070038474152333.06478096651621e-090.5917768214276640.01838925517905960.256763152877773

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Relation with AD stages for SIN3B

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER4.06741515975783e-070.464648434174689
TCX0.0002326750897048780.350252106059612

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RelatedDrugs for SIN3B

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SIN3B

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource