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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for ARHGEF9 |
 Gene summary |
| Gene information | Gene symbol | ARHGEF9 | Gene ID | 23229 |
| Gene name | Cdc42 guanine nucleotide exchange factor 9 | |
| Synonyms | COLLYBISTIN|EIEE8|HPEM-2|PEM-2|PEM2 | |
| Cytomap | Xq11.1 | |
| Type of gene | protein-coding | |
| Description | rho guanine nucleotide exchange factor 9Cdc42 guanine nucleotide exchange factor (GEF) 9PEM-2 homologhPEM-2 collybistinrac/Cdc42 guanine nucleotide exchange factor 9 | |
| Modification date | 20200313 | |
| UniProtAcc | O43307, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for ARHGEF9 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_1505380(63641095, -), ADediting_1505381(63641107, -), ADediting_1505382(63641108, -), ADediting_1505383(63641160, -), ADediting_1505384(63641169, -), ADediting_1505385(63641172, -), ADediting_1505386(63641186, -), ADediting_1505387(63641189, -), ADediting_1505388(63641195, -), ADediting_1505389(63641204, -), ADediting_1505390(63641240, -), ADediting_1505391(63641243, -), ADediting_1505392(63641269, -), ADediting_1505393(63641270, -), ADediting_1505394(63641300, -), ADediting_1505395(63641313, -), ADediting_1505396(63643369, -), ADediting_1505397(63643370, -), ADediting_1505398(63643426, -), ADediting_1505399(63643431, -), ADediting_1505400(63643464, -), ADediting_1505401(63643470, -), ADediting_1505402(63643480, -), ADediting_1505403(63643487, -), ADediting_1505404(63643491, -), ADediting_1505405(63643497, -), ADediting_1505406(63643524, -), ADediting_1505407(63643525, -), ADediting_1505408(63643540, -), ADediting_1505409(63643541, -), ADediting_1505410(63643542, -), ADediting_1505411(63643550, -), ADediting_1505412(63643551, -), ADediting_1505413(63643560, -), ADediting_1505414(63643574, -), ADediting_1505415(63643579, -), ADediting_1505416(63643617, -), ADediting_1505417(63726406, -), ADediting_1505418(63726407, -), ADediting_1505419(63726506, -), ADediting_1505420(63726518, -), ADediting_1505421(63731631, -), ADediting_1505422(63742979, -), ADediting_1505423(63742991, -), ADediting_1505424(63742992, -), ADediting_1505425(63743001, -), ADediting_1505426(63743018, -), ADediting_1505427(63743039, -), ADediting_1505428(63743127, -), ADediting_1505429(63743151, -), ADediting_1505430(63743156, -), ADediting_1505431(63743159, -), ADediting_1505432(63743201, -), ADediting_1505433(63749265, -), ADediting_1505434(63749267, -), ADediting_1505435(63749324, -), ADediting_1505436(63749395, -), ADediting_1505437(63749413, -), ADediting_1505438(63749444, -), ADediting_1505439(63749481, -), ADediting_1505440(63749503, -), ADediting_1505441(63749504, -), ADediting_1505442(63749512, -), ADediting_1505443(63770527, -), ADediting_1675344(63659324, -), |
Top |
RNA editing positional annotations for ARHGEF9 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1505380 | chrX_63641095_- | UTR3 |
| ADediting_1505381 | chrX_63641107_- | UTR3 |
| ADediting_1505382 | chrX_63641108_- | UTR3 |
| ADediting_1505383 | chrX_63641160_- | UTR3 |
| ADediting_1505384 | chrX_63641169_- | UTR3 |
| ADediting_1505385 | chrX_63641172_- | UTR3 |
| ADediting_1505386 | chrX_63641186_- | UTR3 |
| ADediting_1505387 | chrX_63641189_- | UTR3 |
| ADediting_1505388 | chrX_63641195_- | UTR3 |
| ADediting_1505389 | chrX_63641204_- | UTR3 |
| ADediting_1505390 | chrX_63641240_- | UTR3 |
| ADediting_1505391 | chrX_63641243_- | UTR3 |
| ADediting_1505392 | chrX_63641269_- | UTR3 |
| ADediting_1505393 | chrX_63641270_- | UTR3 |
| ADediting_1505394 | chrX_63641300_- | UTR3 |
| ADediting_1505395 | chrX_63641313_- | UTR3 |
| ADediting_1505396 | chrX_63643369_- | intronic |
| ADediting_1505397 | chrX_63643370_- | intronic |
| ADediting_1505398 | chrX_63643426_- | intronic |
| ADediting_1505399 | chrX_63643431_- | intronic |
| ADediting_1505400 | chrX_63643464_- | intronic |
| ADediting_1505401 | chrX_63643470_- | intronic |
| ADediting_1505402 | chrX_63643480_- | intronic |
| ADediting_1505403 | chrX_63643487_- | intronic |
| ADediting_1505404 | chrX_63643491_- | intronic |
| ADediting_1505405 | chrX_63643497_- | intronic |
| ADediting_1505406 | chrX_63643524_- | intronic |
| ADediting_1505407 | chrX_63643525_- | intronic |
| ADediting_1505408 | chrX_63643540_- | intronic |
| ADediting_1505409 | chrX_63643541_- | intronic |
| ADediting_1505410 | chrX_63643542_- | intronic |
| ADediting_1505411 | chrX_63643550_- | intronic |
| ADediting_1505412 | chrX_63643551_- | intronic |
| ADediting_1505413 | chrX_63643560_- | intronic |
| ADediting_1505414 | chrX_63643574_- | intronic |
| ADediting_1505415 | chrX_63643579_- | intronic |
| ADediting_1505416 | chrX_63643617_- | intronic |
| ADediting_1505417 | chrX_63726406_- | intronic |
| ADediting_1505418 | chrX_63726407_- | intronic |
| ADediting_1505419 | chrX_63726506_- | intronic |
| ADediting_1505420 | chrX_63726518_- | intronic |
| ADediting_1505421 | chrX_63731631_- | intronic |
| ADediting_1505422 | chrX_63742979_- | intronic |
| ADediting_1505423 | chrX_63742991_- | intronic |
| ADediting_1505424 | chrX_63742992_- | intronic |
| ADediting_1505425 | chrX_63743001_- | intronic |
| ADediting_1505426 | chrX_63743018_- | intronic |
| ADediting_1505427 | chrX_63743039_- | intronic |
| ADediting_1505428 | chrX_63743127_- | intronic |
| ADediting_1505429 | chrX_63743151_- | intronic |
| ADediting_1505430 | chrX_63743156_- | intronic |
| ADediting_1505431 | chrX_63743159_- | intronic |
| ADediting_1505432 | chrX_63743201_- | intronic |
| ADediting_1505433 | chrX_63749265_- | intronic |
| ADediting_1505434 | chrX_63749267_- | intronic |
| ADediting_1505435 | chrX_63749324_- | intronic |
| ADediting_1505436 | chrX_63749395_- | intronic |
| ADediting_1505437 | chrX_63749413_- | intronic |
| ADediting_1505438 | chrX_63749444_- | intronic |
| ADediting_1505439 | chrX_63749481_- | intronic |
| ADediting_1505440 | chrX_63749503_- | intronic |
| ADediting_1505441 | chrX_63749504_- | intronic |
| ADediting_1505442 | chrX_63749512_- | intronic |
| ADediting_1505443 | chrX_63770527_- | intronic |
| ADediting_1675344 | chrX_63659324_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1505380 | chrX_63641095_- | SINE | Alu | Name=AluSq2 |
| ADediting_1505381 | chrX_63641107_- | SINE | Alu | Name=AluSq2 |
| ADediting_1505382 | chrX_63641108_- | SINE | Alu | Name=AluSq2 |
| ADediting_1505383 | chrX_63641160_- | SINE | Alu | Name=AluSq2 |
| ADediting_1505384 | chrX_63641169_- | SINE | Alu | Name=AluSq2 |
| ADediting_1505385 | chrX_63641172_- | SINE | Alu | Name=AluSq2 |
| ADediting_1505386 | chrX_63641186_- | SINE | Alu | Name=AluSq2 |
| ADediting_1505387 | chrX_63641189_- | SINE | Alu | Name=AluSq2 |
| ADediting_1505388 | chrX_63641195_- | SINE | Alu | Name=AluSq2 |
| ADediting_1505389 | chrX_63641204_- | SINE | Alu | Name=AluSq2 |
| ADediting_1505390 | chrX_63641240_- | SINE | Alu | Name=AluSq2 |
| ADediting_1505391 | chrX_63641243_- | SINE | Alu | Name=AluSq2 |
| ADediting_1505392 | chrX_63641269_- | SINE | Alu | Name=AluSq2 |
| ADediting_1505393 | chrX_63641270_- | SINE | Alu | Name=AluSq2 |
| ADediting_1505394 | chrX_63641300_- | SINE | Alu | Name=AluSq2 |
| ADediting_1505395 | chrX_63641313_- | SINE | Alu | Name=AluSq2 |
| ADediting_1505396 | chrX_63643369_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505397 | chrX_63643370_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505398 | chrX_63643426_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505399 | chrX_63643431_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505400 | chrX_63643464_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505401 | chrX_63643470_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505402 | chrX_63643480_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505403 | chrX_63643487_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505404 | chrX_63643491_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505405 | chrX_63643497_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505406 | chrX_63643524_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505407 | chrX_63643525_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505408 | chrX_63643540_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505409 | chrX_63643541_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505410 | chrX_63643542_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505411 | chrX_63643550_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505412 | chrX_63643551_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505413 | chrX_63643560_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505414 | chrX_63643574_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505415 | chrX_63643579_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505416 | chrX_63643617_- | SINE | Alu | Name=AluSc5 |
| ADediting_1505417 | chrX_63726406_- | SINE | Alu | Name=AluSz6 |
| ADediting_1505418 | chrX_63726407_- | SINE | Alu | Name=AluSz6 |
| ADediting_1505419 | chrX_63726506_- | SINE | Alu | Name=AluSz6 |
| ADediting_1505420 | chrX_63726518_- | SINE | Alu | Name=AluSz6 |
| ADediting_1505421 | chrX_63731631_- | SINE | Alu | Name=AluSx1 |
| ADediting_1505422 | chrX_63742979_- | SINE | Alu | Name=AluSz |
| ADediting_1505423 | chrX_63742991_- | SINE | Alu | Name=AluSz |
| ADediting_1505424 | chrX_63742992_- | SINE | Alu | Name=AluSz |
| ADediting_1505425 | chrX_63743001_- | SINE | Alu | Name=AluSz |
| ADediting_1505426 | chrX_63743018_- | SINE | Alu | Name=AluSz |
| ADediting_1505427 | chrX_63743039_- | SINE | Alu | Name=AluSz |
| ADediting_1505428 | chrX_63743127_- | SINE | Alu | Name=AluSz |
| ADediting_1505429 | chrX_63743151_- | SINE | Alu | Name=AluSz |
| ADediting_1505430 | chrX_63743156_- | SINE | Alu | Name=AluSz |
| ADediting_1505431 | chrX_63743159_- | SINE | Alu | Name=AluSz |
| ADediting_1505432 | chrX_63743201_- | SINE | Alu | Name=AluSz |
| ADediting_1505433 | chrX_63749265_- | SINE | Alu | Name=AluSx |
| ADediting_1505434 | chrX_63749267_- | SINE | Alu | Name=AluSx |
| ADediting_1505435 | chrX_63749324_- | SINE | Alu | Name=AluSx |
| ADediting_1505436 | chrX_63749395_- | SINE | Alu | Name=AluSx |
| ADediting_1505437 | chrX_63749413_- | SINE | Alu | Name=AluSx |
| ADediting_1505438 | chrX_63749444_- | SINE | Alu | Name=AluSx |
| ADediting_1505439 | chrX_63749481_- | SINE | Alu | Name=AluSx |
| ADediting_1505440 | chrX_63749503_- | SINE | Alu | Name=AluSx |
| ADediting_1505441 | chrX_63749504_- | SINE | Alu | Name=AluSx |
| ADediting_1505442 | chrX_63749512_- | SINE | Alu | Name=AluSx |
| ADediting_1505443 | chrX_63770527_- | LTR | ERVL-MaLR | Name=THE1D-int |
Top |
RNA A-to-I editing events in the alternative splicing sites for ARHGEF9 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for ARHGEF9 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |