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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for PTGR1 |
 Gene summary |
| Gene information | Gene symbol | PTGR1 | Gene ID | 22949 |
| Gene name | prostaglandin reductase 1 | |
| Synonyms | LTB4DH|PGR1|ZADH3 | |
| Cytomap | 9q31.3 | |
| Type of gene | protein-coding | |
| Description | prostaglandin reductase 115-oxoprostaglandin 13-reductaseNADP-dependent leukotriene B4 12-hydroxydehydrogenasePRG-1leukotriene B4 12-hydroxydehydrogenasezinc binding alcohol dehydrogenase domain containing 3 | |
| Modification date | 20200313 | |
| UniProtAcc | Q14914, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for PTGR1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_1431262(111589836, -), ADediting_1431263(111590419, -), ADediting_1431264(111590421, -), ADediting_1431265(111590435, -), ADediting_1431266(111590444, -), ADediting_1431267(111590451, -), ADediting_1431268(111590456, -), ADediting_1431269(111590483, -), ADediting_1431270(111590496, -), ADediting_1431271(111590497, -), ADediting_1431272(111590519, -), ADediting_1431273(111590523, -), ADediting_1431274(111590527, -), ADediting_1431275(111590531, -), ADediting_1431276(111590536, -), ADediting_1431277(111590537, -), ADediting_1431278(111590538, -), ADediting_1431279(111590552, -), ADediting_1431280(111590562, -), ADediting_1431281(111590572, -), ADediting_1431282(111590582, -), ADediting_1431283(111590586, -), ADediting_1431284(111590605, -), ADediting_1431285(111590626, -), ADediting_1431286(111590631, -), ADediting_1431287(111590632, -), ADediting_1431288(111590648, -), ADediting_1431289(111591029, -), ADediting_1431290(111591035, -), ADediting_1431291(111591047, -), ADediting_1431292(111591048, -), ADediting_1431293(111591070, -), ADediting_1431294(111591075, -), ADediting_1431295(111591080, -), ADediting_1431296(111591087, -), ADediting_1431297(111591088, -), ADediting_1431298(111591095, -), ADediting_1431299(111591109, -), ADediting_1431300(111591126, -), ADediting_1431301(111591129, -), ADediting_1431302(111591135, -), ADediting_1431303(111591142, -), ADediting_1431304(111591143, -), ADediting_1431305(111591156, -), ADediting_1431306(111591163, -), ADediting_1431307(111591169, -), ADediting_1431308(111591179, -), ADediting_1431309(111591182, -), ADediting_1431310(111591183, -), ADediting_1431311(111591191, -), ADediting_1431312(111591221, -), ADediting_1431313(111591234, -), ADediting_1431314(111591235, -), ADediting_1431315(111591240, -), ADediting_1431316(111591250, -), ADediting_1431317(111591251, -), ADediting_1431318(111591258, -), ADediting_1431319(111591284, -), ADediting_1431320(111591401, -), ADediting_1431321(111591432, -), ADediting_1431322(111591442, -), ADediting_1431323(111591446, -), ADediting_1431324(111591466, -), ADediting_1431325(111591467, -), ADediting_1431326(111591485, -), ADediting_1431327(111591498, -), ADediting_1431328(111591502, -), ADediting_1431329(111591507, -), ADediting_1431330(111591508, -), ADediting_1431331(111591521, -), ADediting_1431332(111591533, -), ADediting_1431333(111591534, -), ADediting_1431334(111591537, -), ADediting_1431335(111591548, -), ADediting_1431336(111591563, -), ADediting_1431337(111591564, -), ADediting_1431338(111591571, -), ADediting_1431339(111591573, -), ADediting_1431340(111591583, -), ADediting_1431341(111591597, -), ADediting_1431342(111591602, -), ADediting_1431343(111591607, -), ADediting_1431344(111591612, -), ADediting_1431345(111591625, -), ADediting_1431346(111591637, -), ADediting_1431347(111591659, -), ADediting_1431348(111591662, -), ADediting_1431349(111593711, -), ADediting_1431350(111594689, -), ADediting_1431351(111594699, -), ADediting_1431352(111594717, -), ADediting_1431353(111594727, -), ADediting_1431354(111594746, -), ADediting_1431355(111594754, -), ADediting_1431356(111594809, -), ADediting_1431357(111594992, -), ADediting_1431358(111595019, -), ADediting_1431359(111595049, -), ADediting_1431360(111595058, -), ADediting_1431361(111595127, -), ADediting_1431362(111595128, -), ADediting_1431363(111595702, -), ADediting_1431364(111595737, -), ADediting_1431365(111595778, -), ADediting_1431366(111595808, -), ADediting_1431367(111595838, -), ADediting_1431368(111595867, -), ADediting_1431369(111595875, -), ADediting_1431370(111595879, -), ADediting_1431371(111595905, -), ADediting_1431372(111595912, -), ADediting_1431373(111596345, -), ADediting_1431374(111596356, -), ADediting_1431375(111596358, -), ADediting_1431376(111596370, -), ADediting_1431377(111596390, -), ADediting_1431378(111596423, -), ADediting_1431379(111596465, -), ADediting_1431380(111596492, -), ADediting_1431381(111596494, -), ADediting_1431382(111596506, -), ADediting_1431383(111596507, -), ADediting_1431384(111596508, -), ADediting_1431385(111596525, -), ADediting_1431386(111596571, -), ADediting_1431387(111596637, -), ADediting_1431388(111596639, -), ADediting_1431389(111596649, -), ADediting_1431390(111596661, -), ADediting_1431391(111596699, -), ADediting_1431392(111596805, -), ADediting_1431393(111596827, -), ADediting_1431394(111596844, -), ADediting_1431395(111596870, -), ADediting_1591934(111590455, -), ADediting_1591935(111590541, -), ADediting_1591936(111598762, -), ADediting_1671612(111591481, -), |
Top |
RNA editing positional annotations for PTGR1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1431262 | chr9_111589836_- | intronic |
| ADediting_1431263 | chr9_111590419_- | intronic |
| ADediting_1431264 | chr9_111590421_- | intronic |
| ADediting_1431265 | chr9_111590435_- | intronic |
| ADediting_1431266 | chr9_111590444_- | intronic |
| ADediting_1431267 | chr9_111590451_- | intronic |
| ADediting_1431268 | chr9_111590456_- | intronic |
| ADediting_1431269 | chr9_111590483_- | intronic |
| ADediting_1431270 | chr9_111590496_- | intronic |
| ADediting_1431271 | chr9_111590497_- | intronic |
| ADediting_1431272 | chr9_111590519_- | intronic |
| ADediting_1431273 | chr9_111590523_- | intronic |
| ADediting_1431274 | chr9_111590527_- | intronic |
| ADediting_1431275 | chr9_111590531_- | intronic |
| ADediting_1431276 | chr9_111590536_- | intronic |
| ADediting_1431277 | chr9_111590537_- | intronic |
| ADediting_1431278 | chr9_111590538_- | intronic |
| ADediting_1431279 | chr9_111590552_- | intronic |
| ADediting_1431280 | chr9_111590562_- | intronic |
| ADediting_1431281 | chr9_111590572_- | intronic |
| ADediting_1431282 | chr9_111590582_- | intronic |
| ADediting_1431283 | chr9_111590586_- | intronic |
| ADediting_1431284 | chr9_111590605_- | intronic |
| ADediting_1431285 | chr9_111590626_- | intronic |
| ADediting_1431286 | chr9_111590631_- | intronic |
| ADediting_1431287 | chr9_111590632_- | intronic |
| ADediting_1431288 | chr9_111590648_- | intronic |
| ADediting_1431289 | chr9_111591029_- | intronic |
| ADediting_1431290 | chr9_111591035_- | intronic |
| ADediting_1431291 | chr9_111591047_- | intronic |
| ADediting_1431292 | chr9_111591048_- | intronic |
| ADediting_1431293 | chr9_111591070_- | intronic |
| ADediting_1431294 | chr9_111591075_- | intronic |
| ADediting_1431295 | chr9_111591080_- | intronic |
| ADediting_1431296 | chr9_111591087_- | intronic |
| ADediting_1431297 | chr9_111591088_- | intronic |
| ADediting_1431298 | chr9_111591095_- | intronic |
| ADediting_1431299 | chr9_111591109_- | intronic |
| ADediting_1431300 | chr9_111591126_- | intronic |
| ADediting_1431301 | chr9_111591129_- | intronic |
| ADediting_1431302 | chr9_111591135_- | intronic |
| ADediting_1431303 | chr9_111591142_- | intronic |
| ADediting_1431304 | chr9_111591143_- | intronic |
| ADediting_1431305 | chr9_111591156_- | intronic |
| ADediting_1431306 | chr9_111591163_- | intronic |
| ADediting_1431307 | chr9_111591169_- | intronic |
| ADediting_1431308 | chr9_111591179_- | intronic |
| ADediting_1431309 | chr9_111591182_- | intronic |
| ADediting_1431310 | chr9_111591183_- | intronic |
| ADediting_1431311 | chr9_111591191_- | intronic |
| ADediting_1431312 | chr9_111591221_- | intronic |
| ADediting_1431313 | chr9_111591234_- | intronic |
| ADediting_1431314 | chr9_111591235_- | intronic |
| ADediting_1431315 | chr9_111591240_- | intronic |
| ADediting_1431316 | chr9_111591250_- | intronic |
| ADediting_1431317 | chr9_111591251_- | intronic |
| ADediting_1431318 | chr9_111591258_- | intronic |
| ADediting_1431319 | chr9_111591284_- | intronic |
| ADediting_1431320 | chr9_111591401_- | intronic |
| ADediting_1431321 | chr9_111591432_- | intronic |
| ADediting_1431322 | chr9_111591442_- | intronic |
| ADediting_1431323 | chr9_111591446_- | intronic |
| ADediting_1431324 | chr9_111591466_- | intronic |
| ADediting_1431325 | chr9_111591467_- | intronic |
| ADediting_1431326 | chr9_111591485_- | intronic |
| ADediting_1431327 | chr9_111591498_- | intronic |
| ADediting_1431328 | chr9_111591502_- | intronic |
| ADediting_1431329 | chr9_111591507_- | intronic |
| ADediting_1431330 | chr9_111591508_- | intronic |
| ADediting_1431331 | chr9_111591521_- | intronic |
| ADediting_1431332 | chr9_111591533_- | intronic |
| ADediting_1431333 | chr9_111591534_- | intronic |
| ADediting_1431334 | chr9_111591537_- | intronic |
| ADediting_1431335 | chr9_111591548_- | intronic |
| ADediting_1431336 | chr9_111591563_- | intronic |
| ADediting_1431337 | chr9_111591564_- | intronic |
| ADediting_1431338 | chr9_111591571_- | intronic |
| ADediting_1431339 | chr9_111591573_- | intronic |
| ADediting_1431340 | chr9_111591583_- | intronic |
| ADediting_1431341 | chr9_111591597_- | intronic |
| ADediting_1431342 | chr9_111591602_- | intronic |
| ADediting_1431343 | chr9_111591607_- | intronic |
| ADediting_1431344 | chr9_111591612_- | intronic |
| ADediting_1431345 | chr9_111591625_- | intronic |
| ADediting_1431346 | chr9_111591637_- | intronic |
| ADediting_1431347 | chr9_111591659_- | intronic |
| ADediting_1431348 | chr9_111591662_- | intronic |
| ADediting_1431349 | chr9_111593711_- | intronic |
| ADediting_1431350 | chr9_111594689_- | intronic |
| ADediting_1431351 | chr9_111594699_- | intronic |
| ADediting_1431352 | chr9_111594717_- | intronic |
| ADediting_1431353 | chr9_111594727_- | intronic |
| ADediting_1431354 | chr9_111594746_- | intronic |
| ADediting_1431355 | chr9_111594754_- | intronic |
| ADediting_1431356 | chr9_111594809_- | intronic |
| ADediting_1431357 | chr9_111594992_- | intronic |
| ADediting_1431358 | chr9_111595019_- | intronic |
| ADediting_1431359 | chr9_111595049_- | intronic |
| ADediting_1431360 | chr9_111595058_- | intronic |
| ADediting_1431361 | chr9_111595127_- | intronic |
| ADediting_1431362 | chr9_111595128_- | intronic |
| ADediting_1431363 | chr9_111595702_- | intronic |
| ADediting_1431364 | chr9_111595737_- | intronic |
| ADediting_1431365 | chr9_111595778_- | intronic |
| ADediting_1431366 | chr9_111595808_- | intronic |
| ADediting_1431367 | chr9_111595838_- | intronic |
| ADediting_1431368 | chr9_111595867_- | intronic |
| ADediting_1431369 | chr9_111595875_- | intronic |
| ADediting_1431370 | chr9_111595879_- | intronic |
| ADediting_1431371 | chr9_111595905_- | intronic |
| ADediting_1431372 | chr9_111595912_- | intronic |
| ADediting_1431373 | chr9_111596345_- | intronic |
| ADediting_1431374 | chr9_111596356_- | intronic |
| ADediting_1431375 | chr9_111596358_- | intronic |
| ADediting_1431376 | chr9_111596370_- | intronic |
| ADediting_1431377 | chr9_111596390_- | intronic |
| ADediting_1431378 | chr9_111596423_- | intronic |
| ADediting_1431379 | chr9_111596465_- | intronic |
| ADediting_1431380 | chr9_111596492_- | intronic |
| ADediting_1431381 | chr9_111596494_- | intronic |
| ADediting_1431382 | chr9_111596506_- | intronic |
| ADediting_1431383 | chr9_111596507_- | intronic |
| ADediting_1431384 | chr9_111596508_- | intronic |
| ADediting_1431385 | chr9_111596525_- | intronic |
| ADediting_1431386 | chr9_111596571_- | intronic |
| ADediting_1431387 | chr9_111596637_- | intronic |
| ADediting_1431388 | chr9_111596639_- | intronic |
| ADediting_1431389 | chr9_111596649_- | intronic |
| ADediting_1431390 | chr9_111596661_- | intronic |
| ADediting_1431391 | chr9_111596699_- | intronic |
| ADediting_1431392 | chr9_111596805_- | intronic |
| ADediting_1431393 | chr9_111596827_- | intronic |
| ADediting_1431394 | chr9_111596844_- | intronic |
| ADediting_1431395 | chr9_111596870_- | intronic |
| ADediting_1591934 | chr9_111590455_- | intronic |
| ADediting_1591935 | chr9_111590541_- | intronic |
| ADediting_1591936 | chr9_111598762_- | intronic |
| ADediting_1671612 | chr9_111591481_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1431262 | chr9_111589836_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431263 | chr9_111590419_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431264 | chr9_111590421_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431265 | chr9_111590435_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431266 | chr9_111590444_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431267 | chr9_111590451_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431268 | chr9_111590456_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431269 | chr9_111590483_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431270 | chr9_111590496_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431271 | chr9_111590497_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431272 | chr9_111590519_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431273 | chr9_111590523_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431274 | chr9_111590527_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431275 | chr9_111590531_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431276 | chr9_111590536_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431277 | chr9_111590537_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431278 | chr9_111590538_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431279 | chr9_111590552_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431280 | chr9_111590562_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431281 | chr9_111590572_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431282 | chr9_111590582_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431283 | chr9_111590586_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431284 | chr9_111590605_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431285 | chr9_111590626_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431286 | chr9_111590631_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431287 | chr9_111590632_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431288 | chr9_111590648_- | SINE | Alu | Name=AluSz6 |
| ADediting_1431289 | chr9_111591029_- | SINE | Alu | Name=AluSp |
| ADediting_1431290 | chr9_111591035_- | SINE | Alu | Name=AluSp |
| ADediting_1431291 | chr9_111591047_- | SINE | Alu | Name=AluSp |
| ADediting_1431292 | chr9_111591048_- | SINE | Alu | Name=AluSp |
| ADediting_1431293 | chr9_111591070_- | SINE | Alu | Name=AluSp |
| ADediting_1431294 | chr9_111591075_- | SINE | Alu | Name=AluSp |
| ADediting_1431295 | chr9_111591080_- | SINE | Alu | Name=AluSp |
| ADediting_1431296 | chr9_111591087_- | SINE | Alu | Name=AluSp |
| ADediting_1431297 | chr9_111591088_- | SINE | Alu | Name=AluSp |
| ADediting_1431298 | chr9_111591095_- | SINE | Alu | Name=AluSp |
| ADediting_1431299 | chr9_111591109_- | SINE | Alu | Name=AluSp |
| ADediting_1431300 | chr9_111591126_- | SINE | Alu | Name=AluSp |
| ADediting_1431301 | chr9_111591129_- | SINE | Alu | Name=AluSp |
| ADediting_1431302 | chr9_111591135_- | SINE | Alu | Name=AluSp |
| ADediting_1431303 | chr9_111591142_- | SINE | Alu | Name=AluSp |
| ADediting_1431304 | chr9_111591143_- | SINE | Alu | Name=AluSp |
| ADediting_1431305 | chr9_111591156_- | SINE | Alu | Name=AluSp |
| ADediting_1431306 | chr9_111591163_- | SINE | Alu | Name=AluSp |
| ADediting_1431307 | chr9_111591169_- | SINE | Alu | Name=AluSp |
| ADediting_1431308 | chr9_111591179_- | SINE | Alu | Name=AluSp |
| ADediting_1431309 | chr9_111591182_- | SINE | Alu | Name=AluSp |
| ADediting_1431310 | chr9_111591183_- | SINE | Alu | Name=AluSp |
| ADediting_1431311 | chr9_111591191_- | SINE | Alu | Name=AluSp |
| ADediting_1431312 | chr9_111591221_- | SINE | Alu | Name=AluSp |
| ADediting_1431313 | chr9_111591234_- | SINE | Alu | Name=AluSp |
| ADediting_1431314 | chr9_111591235_- | SINE | Alu | Name=AluSp |
| ADediting_1431315 | chr9_111591240_- | SINE | Alu | Name=AluSp |
| ADediting_1431316 | chr9_111591250_- | SINE | Alu | Name=AluSp |
| ADediting_1431317 | chr9_111591251_- | SINE | Alu | Name=AluSp |
| ADediting_1431318 | chr9_111591258_- | SINE | Alu | Name=AluSp |
| ADediting_1431319 | chr9_111591284_- | SINE | Alu | Name=AluSp |
| ADediting_1431320 | chr9_111591401_- | SINE | Alu | Name=AluSz |
| ADediting_1431321 | chr9_111591432_- | SINE | Alu | Name=AluSz |
| ADediting_1431322 | chr9_111591442_- | SINE | Alu | Name=AluSz |
| ADediting_1431323 | chr9_111591446_- | SINE | Alu | Name=AluSz |
| ADediting_1431324 | chr9_111591466_- | SINE | Alu | Name=AluSz |
| ADediting_1431325 | chr9_111591467_- | SINE | Alu | Name=AluSz |
| ADediting_1431326 | chr9_111591485_- | SINE | Alu | Name=AluSz |
| ADediting_1431327 | chr9_111591498_- | SINE | Alu | Name=AluSz |
| ADediting_1431328 | chr9_111591502_- | SINE | Alu | Name=AluSz |
| ADediting_1431329 | chr9_111591507_- | SINE | Alu | Name=AluSz |
| ADediting_1431330 | chr9_111591508_- | SINE | Alu | Name=AluSz |
| ADediting_1431331 | chr9_111591521_- | SINE | Alu | Name=AluSz |
| ADediting_1431332 | chr9_111591533_- | SINE | Alu | Name=AluSz |
| ADediting_1431333 | chr9_111591534_- | SINE | Alu | Name=AluSz |
| ADediting_1431334 | chr9_111591537_- | SINE | Alu | Name=AluSz |
| ADediting_1431335 | chr9_111591548_- | SINE | Alu | Name=AluSz |
| ADediting_1431336 | chr9_111591563_- | SINE | Alu | Name=AluSz |
| ADediting_1431337 | chr9_111591564_- | SINE | Alu | Name=AluSz |
| ADediting_1431338 | chr9_111591571_- | SINE | Alu | Name=AluSz |
| ADediting_1431339 | chr9_111591573_- | SINE | Alu | Name=AluSz |
| ADediting_1431340 | chr9_111591583_- | SINE | Alu | Name=AluSz |
| ADediting_1431341 | chr9_111591597_- | SINE | Alu | Name=AluSz |
| ADediting_1431342 | chr9_111591602_- | SINE | Alu | Name=AluSz |
| ADediting_1431343 | chr9_111591607_- | SINE | Alu | Name=AluSz |
| ADediting_1431344 | chr9_111591612_- | SINE | Alu | Name=AluSz |
| ADediting_1431345 | chr9_111591625_- | SINE | Alu | Name=AluSz |
| ADediting_1431346 | chr9_111591637_- | SINE | Alu | Name=AluSz |
| ADediting_1431347 | chr9_111591659_- | SINE | Alu | Name=AluSz |
| ADediting_1431348 | chr9_111591662_- | SINE | Alu | Name=AluSz |
| ADediting_1431349 | chr9_111593711_- | SINE | Alu | Name=AluSx3 |
| ADediting_1431350 | chr9_111594689_- | SINE | Alu | Name=AluY |
| ADediting_1431351 | chr9_111594699_- | SINE | Alu | Name=AluY |
| ADediting_1431352 | chr9_111594717_- | SINE | Alu | Name=AluY |
| ADediting_1431353 | chr9_111594727_- | SINE | Alu | Name=AluY |
| ADediting_1431354 | chr9_111594746_- | SINE | Alu | Name=AluY |
| ADediting_1431355 | chr9_111594754_- | SINE | Alu | Name=AluY |
| ADediting_1431356 | chr9_111594809_- | SINE | Alu | Name=AluY |
| ADediting_1431357 | chr9_111594992_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431358 | chr9_111595019_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431359 | chr9_111595049_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431360 | chr9_111595058_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431361 | chr9_111595127_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431362 | chr9_111595128_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431363 | chr9_111595702_- | SINE | Alu | Name=AluY |
| ADediting_1431364 | chr9_111595737_- | SINE | Alu | Name=AluY |
| ADediting_1431365 | chr9_111595778_- | SINE | Alu | Name=AluY |
| ADediting_1431366 | chr9_111595808_- | SINE | Alu | Name=AluY |
| ADediting_1431367 | chr9_111595838_- | SINE | Alu | Name=AluY |
| ADediting_1431368 | chr9_111595867_- | SINE | Alu | Name=AluY |
| ADediting_1431369 | chr9_111595875_- | SINE | Alu | Name=AluY |
| ADediting_1431370 | chr9_111595879_- | SINE | Alu | Name=AluY |
| ADediting_1431371 | chr9_111595905_- | SINE | Alu | Name=AluY |
| ADediting_1431372 | chr9_111595912_- | SINE | Alu | Name=AluY |
| ADediting_1431373 | chr9_111596345_- | SINE | Alu | Name=AluSx |
| ADediting_1431374 | chr9_111596356_- | SINE | Alu | Name=AluSx |
| ADediting_1431375 | chr9_111596358_- | SINE | Alu | Name=AluSx |
| ADediting_1431376 | chr9_111596370_- | SINE | Alu | Name=AluSx |
| ADediting_1431377 | chr9_111596390_- | SINE | Alu | Name=AluSx |
| ADediting_1431378 | chr9_111596423_- | SINE | Alu | Name=AluSx |
| ADediting_1431379 | chr9_111596465_- | SINE | Alu | Name=AluSx |
| ADediting_1431380 | chr9_111596492_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431381 | chr9_111596494_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431382 | chr9_111596506_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431383 | chr9_111596507_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431384 | chr9_111596508_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431385 | chr9_111596525_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431386 | chr9_111596571_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431387 | chr9_111596637_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431388 | chr9_111596639_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431389 | chr9_111596649_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431390 | chr9_111596661_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431391 | chr9_111596699_- | SINE | Alu | Name=AluSx1 |
| ADediting_1431392 | chr9_111596805_- | SINE | Alu | Name=AluSx |
| ADediting_1431393 | chr9_111596827_- | SINE | Alu | Name=AluSx |
| ADediting_1431394 | chr9_111596844_- | SINE | Alu | Name=AluSx |
| ADediting_1431395 | chr9_111596870_- | SINE | Alu | Name=AluSx |
| ADediting_1591934 | chr9_111590455_- | SINE | Alu | Name=AluSz6 |
| ADediting_1591935 | chr9_111590541_- | SINE | Alu | Name=AluSz6 |
| ADediting_1591936 | chr9_111598762_- | SINE | Alu | Name=AluSx1 |
| ADediting_1671612 | chr9_111591481_- | SINE | Alu | Name=AluSz |
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RNA A-to-I editing events in the alternative splicing sites for PTGR1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PTGR1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for PTGR1 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for PTGR1 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1556067 | chr19_40282625_- | ENSG00000106853.20 | ENST00000309195.9 | PTGR1-201 | hsa-miR-641 | chr9 | 111563027 | 111563034 | 8mer-1a | 111563027 | 111563053 | 154 | -12.77 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000106853.20 | ENST00000407693.7 | PTGR1-205 | hsa-miR-641 | chr9 | 111563027 | 111563034 | 8mer-1a | 111563027 | 111563053 | 154 | -12.77 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000106853.20 | ENST00000309195.9 | PTGR1-201 | hsa-miR-641 | chr9 | 111563027 | 111563034 | 8mer-1a | 111563027 | 111563053 | 154 | -12.77 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000106853.20 | ENST00000407693.7 | PTGR1-205 | hsa-miR-641 | chr9 | 111563027 | 111563034 | 8mer-1a | 111563027 | 111563053 | 154 | -12.77 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000106853.20 | ENST00000407693.7 | PTGR1-205 | hsa-miR-4775 | chr9 | 111562585 | 111562591 | 7mer-1a | 111562572 | 111562593 | 150 | -6.45 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for PTGR1 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for PTGR1 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_1431283 | chr9_111590586_- | 2.84131617893382e-05 | 0.235342072086815 | 6.63499255866496e-09 | 0.32190397644119 | 0.181821240751871 | 0.0760298079252369 |
| TCX | ADediting_1431283 | chr9_111590586_- | 0.00555316388752488 | 0.22538410541636 | 1.00964520494479e-06 | 0.386828311926336 | 0.0166021149849415 | -0.195330026423401 |
| DLPFC | ADediting_1431291 | chr9_111591047_- | 7.2481736237068e-05 | 0.223414086147364 | 2.39134799903406e-09 | 0.33074792278894 | 0.0525258103103469 | 0.11022591801098 |
| PCC | ADediting_1431291 | chr9_111591047_- | 8.36304651499887e-06 | 0.316167605422554 | 6.49819755393896e-07 | 0.350828821704801 | 0.871065031863377 | 0.0118212246788366 |
| TCX | ADediting_1431291 | chr9_111591047_- | 0.00010859478174509 | 0.310766543043833 | 3.91771053520895e-07 | 0.400113228349774 | 0.0209752508955532 | -0.188367736712382 |
| TCX | ADediting_1431294 | chr9_111591075_- | 0.0288539726784586 | 0.17850094163322 | 7.70910394772191e-06 | 0.356157919800867 | 0.0101983100205483 | -0.209184512049914 |
| TCX | ADediting_1431298 | chr9_111591095_- | 0.0245386024208943 | 0.183569184000543 | 0.000136661462684123 | 0.306459139748916 | 0.0424409942396383 | -0.165918815355046 |
| TCX | ADediting_1431301 | chr9_111591129_- | 0.00928118861387861 | 0.211769930198027 | 3.51767807799067e-05 | 0.330988092296689 | 0.148127082866214 | -0.118655038156401 |
| TCX | ADediting_1431315 | chr9_111591240_- | 0.000232293085356603 | 0.296257367897041 | 1.39234446681428e-05 | 0.346611388938044 | 0.266055557095767 | -0.0913844197339175 |
| TCX | ADediting_1431318 | chr9_111591258_- | 4.68800234830317e-05 | 0.32597035728474 | 4.80541546371141e-06 | 0.363574945533827 | 0.188528056888111 | -0.107953922333089 |
| TCX | ADediting_1431344 | chr9_111591612_- | 0.00238897843545587 | 0.246205814945561 | 7.267273921369e-05 | 0.31813784331763 | 0.0968742955921222 | -0.136061805931506 |
| CER | ADediting_1431345 | chr9_111591625_- | 0.00499072306807304 | 0.2281198793809 | 2.08929191504873e-05 | 0.339873218852268 | 0.923585829667771 | 0.00789760363410311 |
| TCX | ADediting_1431345 | chr9_111591625_- | 1.04512982993187e-06 | 0.386332421318133 | 1.30222742079028e-07 | 0.414876281600336 | 0.175751431923079 | -0.111136706814293 |
| DLPFC | ADediting_1431375 | chr9_111596358_- | 0.138788564878363 | 0.0842671907798436 | 0.47427360667223 | -0.0407879671458438 | 6.0954245610017e-13 | 0.393791032670217 |
| DLPFC | ADediting_1431382 | chr9_111596506_- | 0.258893572352584 | 0.0643168772825534 | 0.2747976222453 | -0.0622172502203575 | 3.56670352598022e-19 | 0.478859940857706 |
| DLPFC | ADediting_1431394 | chr9_111596844_- | 0.0896958209290952 | 0.0965481218450674 | 0.514314025675125 | 0.037176161192027 | 3.1627923340582e-09 | 0.328352922114064 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 8.83724739684563e-73 | 0.808127529482542 | 8.5101469001524e-66 | 0.784193778791364 | 0.187346530480103 | 0.0750816094353512 |
| AC | 4.09631185068739e-117 | 0.939186182271489 | 3.31249344320191e-65 | 0.83132768349036 | 3.97343062504603e-10 | 0.382385096829979 |
| PCC | 9.91126977798365e-60 | 0.869261752813639 | 9.78150667822102e-63 | 0.879117524277567 | 0.0233877785567751 | 0.164001540982358 |
| CER | 7.50094360401259e-34 | 0.79434946115502 | 1.4879595416545e-28 | 0.751785393313032 | 0.0353638567300296 | 0.17196113424794 |
| TCX | 3.69968106642755e-44 | 0.855553342169129 | 6.47370807275339e-29 | 0.75499660712802 | 0.542565306141624 | -0.0501075331779985 |
| FP | 7.12677442708611e-22 | 0.639723551650141 | 1.24311546777457e-14 | 0.536086531979853 | 0.545378760963929 | 0.0456219449562961 |
| IFG | 0.000347246854224437 | 0.65828914608512 | 0.000164353833496374 | 0.683763257692104 | 0.919450014794638 | 0.0213142863852385 |
| PG | 2.18628675583098e-52 | 0.847029168142164 | 1.7625271645153e-24 | 0.658361213805447 | 0.778676389393314 | -0.0207448000443939 |
| STG | 2.19376850258725e-11 | 0.650157870204036 | 4.79760551810307e-08 | 0.553327959599557 | 0.0780439714678191 | -0.193344730780616 |
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Relation with AD stages for PTGR1 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
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RelatedDrugs for PTGR1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PTGR1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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