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	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited versus non-edited samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with AD stages
	Related drugs with this gene
	Related diseases with this gene

Gene summary for RALY

Gene summary

Gene information	Gene symbol	RALY
	Gene ID	22913
	Gene name	RALY heterogeneous nuclear ribonucleoprotein
	Synonyms	HNRPCL2|P542
	Cytomap	20q11.22
	Type of gene	protein-coding
	Description	RNA-binding protein RalyRNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog)RNA-binding protein (autoantigenic)RNA-binding protein (autoantigenic, hnRNP-associated with lethal yellow)autoantigen p542heterogeneous nuclear r
	Modification date	20200327
	UniProtAcc	Q9UKM9,
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for RALY

RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA editing frequencies across three data sets.

The number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA A-to-I editing events in AD.

ADediting_923891(33997216, +), ADediting_923892(33997232, +), ADediting_923893(33997295, +), ADediting_923894(33998951, +), ADediting_923895(33998983, +), ADediting_923896(33999010, +), ADediting_923905(34010341, +), ADediting_923906(34012010, +), ADediting_923909(34025509, +), ADediting_923910(34025556, +), ADediting_923911(34025566, +), ADediting_923912(34028166, +), ADediting_923913(34028211, +), ADediting_923915(34032019, +), ADediting_923916(34032024, +), ADediting_923917(34032063, +), ADediting_923918(34032066, +), ADediting_923919(34032067, +), ADediting_923920(34032096, +), ADediting_923922(34032146, +), ADediting_923923(34032225, +), ADediting_923924(34032237, +), ADediting_923925(34032240, +), ADediting_923930(34034898, +), ADediting_923931(34034965, +), ADediting_923932(34035006, +), ADediting_923933(34035032, +), ADediting_923934(34035038, +), ADediting_923935(34035042, +), ADediting_923936(34035059, +), ADediting_923937(34035062, +), ADediting_923938(34035085, +), ADediting_923951(34044610, +), ADediting_923955(34046876, +), ADediting_923956(34046949, +), ADediting_923958(34048753, +), ADediting_923959(34048801, +), ADediting_923963(34054683, +), ADediting_923964(34054715, +), ADediting_923965(34054746, +), ADediting_923966(34054747, +), ADediting_923967(34073913, +), ADediting_923968(34074005, +), ADediting_923969(34074057, +), ADediting_923970(34074602, +), ADediting_923971(34074610, +), ADediting_923972(34085153, +), ADediting_923973(34085163, +), ADediting_923974(34085180, +), ADediting_923975(34086027, +), ADediting_923976(34086057, +), ADediting_923977(34086059, +), ADediting_923978(34086110, +), ADediting_923979(34087196, +), ADediting_923980(34087236, +), ADediting_923981(34087240, +), ADediting_923982(34087329, +), ADediting_923983(34087355, +), ADediting_923984(34087381, +), ADediting_923985(34087644, +), ADediting_923986(34087648, +), ADediting_923987(34087649, +), ADediting_923988(34087684, +), ADediting_923989(34087734, +), ADediting_923990(34087760, +), ADediting_1565808(34074631, +), ADediting_1565809(34074639, +), ADediting_1565810(34074644, +), ADediting_1565811(34085111, +), ADediting_1565812(34085121, +), ADediting_1565813(34085127, +), ADediting_1565814(34085195, +), ADediting_1565815(34086091, +), ADediting_1565816(34086197, +), ADediting_1565817(34086200, +), ADediting_1640463(34005327, +),

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RNA editing positional annotations for RALY using Annovar

Protein coding RNA editing(s).

ADeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

ADeditome ID	Position	Variant type
ADediting_923891	chr20_33997216_+	intronic
ADediting_923892	chr20_33997232_+	intronic
ADediting_923893	chr20_33997295_+	intronic
ADediting_923894	chr20_33998951_+	intronic
ADediting_923895	chr20_33998983_+	intronic
ADediting_923896	chr20_33999010_+	intronic
ADediting_923905	chr20_34010341_+	intronic
ADediting_923906	chr20_34012010_+	intronic
ADediting_923909	chr20_34025509_+	intronic
ADediting_923910	chr20_34025556_+	intronic
ADediting_923911	chr20_34025566_+	intronic
ADediting_923912	chr20_34028166_+	intronic
ADediting_923913	chr20_34028211_+	intronic
ADediting_923915	chr20_34032019_+	intronic
ADediting_923916	chr20_34032024_+	intronic
ADediting_923917	chr20_34032063_+	intronic
ADediting_923918	chr20_34032066_+	intronic
ADediting_923919	chr20_34032067_+	intronic
ADediting_923920	chr20_34032096_+	intronic
ADediting_923922	chr20_34032146_+	intronic
ADediting_923923	chr20_34032225_+	intronic
ADediting_923924	chr20_34032237_+	intronic
ADediting_923925	chr20_34032240_+	intronic
ADediting_923930	chr20_34034898_+	intronic
ADediting_923931	chr20_34034965_+	intronic
ADediting_923932	chr20_34035006_+	intronic
ADediting_923933	chr20_34035032_+	intronic
ADediting_923934	chr20_34035038_+	intronic
ADediting_923935	chr20_34035042_+	intronic
ADediting_923936	chr20_34035059_+	intronic
ADediting_923937	chr20_34035062_+	intronic
ADediting_923938	chr20_34035085_+	intronic
ADediting_923951	chr20_34044610_+	intronic
ADediting_923955	chr20_34046876_+	intronic
ADediting_923956	chr20_34046949_+	intronic
ADediting_923958	chr20_34048753_+	intronic
ADediting_923959	chr20_34048801_+	intronic
ADediting_923963	chr20_34054683_+	intronic
ADediting_923964	chr20_34054715_+	intronic
ADediting_923965	chr20_34054746_+	intronic
ADediting_923966	chr20_34054747_+	intronic
ADediting_923967	chr20_34073913_+	intronic
ADediting_923968	chr20_34074005_+	intronic
ADediting_923969	chr20_34074057_+	intronic
ADediting_923970	chr20_34074602_+	intronic
ADediting_923971	chr20_34074610_+	intronic
ADediting_923972	chr20_34085153_+	downstream
ADediting_923973	chr20_34085163_+	downstream
ADediting_923974	chr20_34085180_+	downstream
ADediting_923975	chr20_34086027_+	intergenic
ADediting_923976	chr20_34086057_+	intergenic
ADediting_923977	chr20_34086059_+	intergenic
ADediting_923978	chr20_34086110_+	intergenic
ADediting_923979	chr20_34087196_+	intergenic
ADediting_923980	chr20_34087236_+	intergenic
ADediting_923981	chr20_34087240_+	intergenic
ADediting_923982	chr20_34087329_+	downstream
ADediting_923983	chr20_34087355_+	downstream
ADediting_923984	chr20_34087381_+	downstream
ADediting_923985	chr20_34087644_+	downstream
ADediting_923986	chr20_34087648_+	downstream
ADediting_923987	chr20_34087649_+	downstream
ADediting_923988	chr20_34087684_+	downstream
ADediting_923989	chr20_34087734_+	downstream
ADediting_923990	chr20_34087760_+	downstream
ADediting_1565808	chr20_34074631_+	intronic
ADediting_1565809	chr20_34074639_+	intronic
ADediting_1565810	chr20_34074644_+	intronic
ADediting_1565811	chr20_34085111_+	downstream
ADediting_1565812	chr20_34085121_+	downstream
ADediting_1565813	chr20_34085127_+	downstream
ADediting_1565814	chr20_34085195_+	downstream
ADediting_1565815	chr20_34086091_+	intergenic
ADediting_1565816	chr20_34086197_+	intergenic
ADediting_1565817	chr20_34086200_+	intergenic
ADediting_1640463	chr20_34005327_+	intronic

Repat-regional RNA editing(s).

ADeditome ID	Position	Repeat family	Repeat sub family	Repeat name
ADediting_923891	chr20_33997216_+	SINE	Alu	Name=AluSx
ADediting_923892	chr20_33997232_+	SINE	Alu	Name=AluSx
ADediting_923893	chr20_33997295_+	SINE	Alu	Name=AluSx
ADediting_923894	chr20_33998951_+	SINE	Alu	Name=AluSx1
ADediting_923895	chr20_33998983_+	SINE	Alu	Name=AluSx1
ADediting_923896	chr20_33999010_+	SINE	Alu	Name=AluSx1
ADediting_923905	chr20_34010341_+	SINE	Alu	Name=AluJr
ADediting_923906	chr20_34012010_+	SINE	Alu	Name=AluSz
ADediting_923909	chr20_34025509_+	SINE	Alu	Name=AluSx
ADediting_923910	chr20_34025556_+	SINE	Alu	Name=AluSx
ADediting_923911	chr20_34025566_+	SINE	Alu	Name=AluSx
ADediting_923912	chr20_34028166_+	SINE	Alu	Name=AluSz
ADediting_923913	chr20_34028211_+	SINE	Alu	Name=AluSz
ADediting_923915	chr20_34032019_+	SINE	Alu	Name=AluSp
ADediting_923916	chr20_34032024_+	SINE	Alu	Name=AluSp
ADediting_923917	chr20_34032063_+	SINE	Alu	Name=AluSp
ADediting_923918	chr20_34032066_+	SINE	Alu	Name=AluSp
ADediting_923919	chr20_34032067_+	SINE	Alu	Name=AluSp
ADediting_923920	chr20_34032096_+	SINE	Alu	Name=AluSp
ADediting_923922	chr20_34032146_+	SINE	Alu	Name=AluSp
ADediting_923923	chr20_34032225_+	SINE	Alu	Name=AluSp
ADediting_923924	chr20_34032237_+	SINE	Alu	Name=AluSp
ADediting_923925	chr20_34032240_+	SINE	Alu	Name=AluSp
ADediting_923930	chr20_34034898_+	SINE	Alu	Name=AluY
ADediting_923931	chr20_34034965_+	SINE	Alu	Name=AluY
ADediting_923932	chr20_34035006_+	SINE	Alu	Name=AluY
ADediting_923933	chr20_34035032_+	SINE	Alu	Name=AluY
ADediting_923934	chr20_34035038_+	SINE	Alu	Name=AluY
ADediting_923935	chr20_34035042_+	SINE	Alu	Name=AluY
ADediting_923936	chr20_34035059_+	SINE	Alu	Name=AluY
ADediting_923937	chr20_34035062_+	SINE	Alu	Name=AluY
ADediting_923938	chr20_34035085_+	SINE	Alu	Name=AluY
ADediting_923951	chr20_34044610_+	SINE	Alu	Name=AluSp
ADediting_923955	chr20_34046876_+	SINE	Alu	Name=AluSp
ADediting_923956	chr20_34046949_+	SINE	Alu	Name=AluSp
ADediting_923958	chr20_34048753_+	SINE	Alu	Name=AluY
ADediting_923959	chr20_34048801_+	SINE	Alu	Name=AluY
ADediting_923963	chr20_34054683_+	SINE	Alu	Name=AluSz
ADediting_923964	chr20_34054715_+	SINE	Alu	Name=AluSz
ADediting_923965	chr20_34054746_+	SINE	Alu	Name=AluSz
ADediting_923966	chr20_34054747_+	SINE	Alu	Name=AluSz
ADediting_923967	chr20_34073913_+	SINE	MIR	Name=MIR3
ADediting_923968	chr20_34074005_+	SINE	MIR	Name=MIR3
ADediting_923969	chr20_34074057_+	SINE	MIR	Name=MIR3
ADediting_923970	chr20_34074602_+	SINE	MIR	Name=MIRc
ADediting_923971	chr20_34074610_+	SINE	MIR	Name=MIRc
ADediting_923972	chr20_34085153_+	SINE	Alu	Name=AluY
ADediting_923973	chr20_34085163_+	SINE	Alu	Name=AluY
ADediting_923974	chr20_34085180_+	SINE	Alu	Name=AluY
ADediting_923975	chr20_34086027_+	SINE	Alu	Name=AluJb
ADediting_923976	chr20_34086057_+	SINE	Alu	Name=AluJb
ADediting_923977	chr20_34086059_+	SINE	Alu	Name=AluJb
ADediting_923978	chr20_34086110_+	SINE	Alu	Name=AluJb
ADediting_923979	chr20_34087196_+	SINE	Alu	Name=AluSx1
ADediting_923980	chr20_34087236_+	SINE	Alu	Name=AluSx1
ADediting_923981	chr20_34087240_+	SINE	Alu	Name=AluSx1
ADediting_923982	chr20_34087329_+	SINE	Alu	Name=AluSx1
ADediting_923983	chr20_34087355_+	SINE	Alu	Name=AluSx1
ADediting_923984	chr20_34087381_+	SINE	Alu	Name=AluSx1
ADediting_923985	chr20_34087644_+	SINE	Alu	Name=AluSx3
ADediting_923986	chr20_34087648_+	SINE	Alu	Name=AluSx3
ADediting_923987	chr20_34087649_+	SINE	Alu	Name=AluSx3
ADediting_923988	chr20_34087684_+	SINE	Alu	Name=AluSx3
ADediting_923989	chr20_34087734_+	SINE	Alu	Name=AluSx3
ADediting_923990	chr20_34087760_+	SINE	Alu	Name=AluSx3
ADediting_1565808	chr20_34074631_+	SINE	MIR	Name=MIRc
ADediting_1565809	chr20_34074639_+	SINE	MIR	Name=MIRc
ADediting_1565810	chr20_34074644_+	SINE	MIR	Name=MIRc
ADediting_1565811	chr20_34085111_+	SINE	Alu	Name=AluY
ADediting_1565812	chr20_34085121_+	SINE	Alu	Name=AluY
ADediting_1565813	chr20_34085127_+	SINE	Alu	Name=AluY
ADediting_1565814	chr20_34085195_+	SINE	Alu	Name=AluY
ADediting_1565815	chr20_34086091_+	SINE	Alu	Name=AluJb
ADediting_1565816	chr20_34086197_+	SINE	Alu	Name=AluJb
ADediting_1565817	chr20_34086200_+	SINE	Alu	Name=AluJb
ADediting_1640463	chr20_34005327_+	SINE	Alu	Name=AluSc5

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RNA A-to-I editing events in the alternative splicing sites for RALY

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

ADeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for RALY

Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A.

Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window.

- Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window.

ADeditome ID

Chr

Positoing

Skipped exon

ENSG

ENSTs

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Protein coding region RNA A-to-I editings for RALY

- Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for RALY

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_1337757

chr7_5495852_-

ENSG00000125970.12

ENST00000246194.8

RALY-201

hsa-miR-589-3p

chr20

34084590

34084596

7mer-m8

34084572

34084597

142

-18.14

ADediting_1337757

chr7_5495852_-

ENSG00000125970.12

ENST00000375114.7

RALY-203

hsa-miR-589-3p

chr20

34084590

34084596

7mer-m8

34084572

34084597

142

-18.14

ADediting_1631458

chr19_40282624_-

ENSG00000125970.12

ENST00000246194.8

RALY-201

hsa-miR-641

chr20

34080059

34080065

7mer-m8

34080043

34080066

147

-14.8

ADediting_1631458

chr19_40282624_-

ENSG00000125970.12

ENST00000375114.7

RALY-203

hsa-miR-641

chr20

34080059

34080065

7mer-m8

34080043

34080066

147

-14.8

ADediting_496066

chr15_66496985_-

ENSG00000125970.12

ENST00000246194.8

RALY-201

hsa-miR-4512

chr20

34082007

34082013

7mer-m8

34081995

34082014

149

-25.45

ADediting_496066

chr15_66496985_-

ENSG00000125970.12

ENST00000375114.7

RALY-203

hsa-miR-4512

chr20

34082007

34082013

7mer-m8

34081995

34082014

149

-25.45

ADediting_98288

chr1_32086990_+

ENSG00000125970.12

ENST00000246194.8

RALY-201

hsa-miR-5585-3p

chr20

34082572

34082578

7mer-m8

34082555

34082579

148

-17.13

ADediting_98288

chr1_32086990_+

ENSG00000125970.12

ENST00000375114.7

RALY-203

hsa-miR-5585-3p

chr20

34082572

34082578

7mer-m8

34082555

34082579

148

-17.13

ADediting_98289

chr1_32086992_+

ENSG00000125970.12

ENST00000246194.8

RALY-201

hsa-miR-5585-3p

chr20

34084830

34084837

8mer-1a

34084816

34084837

145

-14.64

ADediting_98289

chr1_32086992_+

ENSG00000125970.12

ENST00000375114.7

RALY-203

hsa-miR-5585-3p

chr20

34084830

34084837

8mer-1a

34084816

34084837

145

-14.64

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_1337757

chr7_5495852_-

ENSG00000125970.12

ENST00000246194.8

RALY-201

hsa-miR-589-3p

chr20

34080263

34080270

8mer-1a

34080248

34080270

148

-17.21

ADediting_1337757

chr7_5495852_-

ENSG00000125970.12

ENST00000375114.7

RALY-203

hsa-miR-589-3p

chr20

34080263

34080270

8mer-1a

34080248

34080270

148

-17.21

ADediting_527135

chr16_24203190_+

ENSG00000125970.12

ENST00000246194.8

RALY-201

hsa-miR-1273h-3p

chr20

34080112

34080118

7mer-m8

34080098

34080119

140

-12.13

ADediting_527135

chr16_24203190_+

ENSG00000125970.12

ENST00000246194.8

RALY-201

hsa-miR-1273h-3p

chr20

34082104

34082111

8mer-1a

34082090

34082111

152

-18.69

ADediting_527135

chr16_24203190_+

ENSG00000125970.12

ENST00000375114.7

RALY-203

hsa-miR-1273h-3p

chr20

34080112

34080118

7mer-m8

34080098

34080119

140

-12.13

ADediting_527135

chr16_24203190_+

ENSG00000125970.12

ENST00000375114.7

RALY-203

hsa-miR-1273h-3p

chr20

34082104

34082111

8mer-1a

34082090

34082111

152

-18.69

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for RALY

- RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in miRNA.

ADeditom_ID

ENST

mir_ID

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

RNA A-to-I editing in mRNA.

ADeditom_ID

ENST

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

RNA A-to-I editing in lncRNA.

ADeditom_ID

ENST

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for RALY

Correlation between ADAR gene expression and RNA editing frequency

Tissue	ADeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
DLPFC	ADediting_923896	chr20_33999010_+	0.386471051721701	-0.0493568782860332	0.00851703069851398	-0.149188103981507	2.41500815178374e-13	0.400066021912691
CER	ADediting_923967	chr20_34073913_+	1.52500574061045e-05	0.345113797821207	4.32972342124857e-06	0.365186089472186	0.182384439947632	0.109463911946757
TCX	ADediting_923967	chr20_34073913_+	0.780033792329775	0.0229920321542408	0.141787713665098	-0.120527433870815	1.78285168545596e-07	0.410737630595091
CER	ADediting_923968	chr20_34074005_+	0.000184552557922364	0.300727861039808	3.00886605059371e-05	0.333681433805421	0.434796768385781	0.064240674989429
CER	ADediting_923970	chr20_34074602_+	7.4103276469244e-06	0.356785343560785	0.000274202085593048	0.292988762377901	0.868982783888358	-0.013581160244743
CER	ADediting_923971	chr20_34074610_+	6.65136739535722e-09	0.451536893220568	4.35040599913827e-08	0.42890015421292	0.261444944621285	0.0922672508387314

Correlation between ADAR gene expression and this gene's expression

Tissue	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
DLPFC	3.01524829199155e-28	0.571245868585831	2.07221997158248e-10	0.350866924276144	5.91905252022362e-48	0.705391016709091
AC	3.88895233984883e-48	0.759082764961466	6.20836383645489e-27	0.610583316532522	7.8088569605187e-27	0.609638006678854
PCC	1.31103700192391e-17	0.566558164315693	3.72018198590532e-18	0.574356138655434	0.00166129342131073	0.226089040431364
CER	2.00951708495401e-23	0.700282582868859	8.98155142415618e-14	0.560284356925662	0.000391954340642971	0.285812456661704
TCX	3.51411006717207e-16	0.602359520240133	0.333654447084136	0.0794770982645596	5.6542799031835e-20	0.658118887343404
FP	2.135813251335e-27	0.698741758077499	4.70550141506721e-22	0.641875843381251	1.56474144938237e-06	0.350940392792093
IFG	0.000782605098664996	0.627676150832842	0.0293760790145783	0.435939322950766	0.0197469373831411	0.463069217063142
STG	5.81382064578357e-17	0.759215669893786	2.31231536673126e-08	0.564018860695939	0.00992294741012525	0.27988466422313

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Relation with AD stages for RALY

Correlation between AD stages and RNA editing frequency

Tissue	ADeditomID	position	P-val	Coeff.
CER	ADediting_923971	chr20_34074610_+	0.000297206453008467	0.341559827017445
TCX	ADediting_923967	chr20_34073913_+	3.60670425628326e-05	0.389893104149972
TCX	ADediting_923968	chr20_34074005_+	0.000382032261067607	0.338775504041597

Correlation between AD stages and this gene's expression

Tissue	P-val	Coeff.
TCX	1.32400123613133e-06	0.449711559403942

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RelatedDrugs for RALY

Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for RALY

Diseases associated with this gene. (DisGeNet 4.0)

Gene	Disease ID	Disease name	# pubmeds	Source
RALY	C0236733	Amphetamine-Related Disorders	1	CTD_human
RALY	C0236804	Amphetamine Addiction	1	CTD_human
RALY	C0236807	Amphetamine Abuse	1	CTD_human

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