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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for LRRN4CL |
 Gene summary |
| Gene information | Gene symbol | LRRN4CL | Gene ID | 221091 |
| Gene name | LRRN4 C-terminal like | |
| Synonyms | - | |
| Cytomap | 11q12.3 | |
| Type of gene | protein-coding | |
| Description | LRRN4 C-terminal-like protein | |
| Modification date | 20200313 | |
| UniProtAcc | Q8ND94, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for LRRN4CL |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_262237(62686731, -), ADediting_262238(62686767, -), ADediting_262239(62686768, -), ADediting_262240(62686803, -), ADediting_262241(62686809, -), ADediting_262242(62686835, -), ADediting_262243(62686839, -), ADediting_262244(62686841, -), ADediting_262245(62686850, -), ADediting_262246(62686864, -), ADediting_262247(62686941, -), ADediting_262248(62686942, -), ADediting_262249(62687015, -), ADediting_262250(62687017, -), ADediting_262251(62687023, -), ADediting_262252(62687035, -), ADediting_262253(62687054, -), ADediting_262254(62687063, -), ADediting_262255(62687077, -), ADediting_262256(62687096, -), ADediting_262257(62687113, -), ADediting_262258(62687157, -), ADediting_262259(62687159, -), ADediting_262260(62687169, -), ADediting_262261(62687198, -), ADediting_262262(62687212, -), ADediting_262263(62687224, -), ADediting_262264(62687242, -), ADediting_262265(62687254, -), ADediting_1527357(62686782, -), ADediting_1527358(62686840, -), ADediting_1527359(62686847, -), ADediting_1527360(62686849, -), ADediting_1527361(62686874, -), ADediting_1527362(62686902, -), ADediting_1527363(62686911, -), ADediting_1527364(62686950, -), ADediting_1527365(62687014, -), ADediting_1527366(62687036, -), ADediting_1527367(62687116, -), ADediting_1527368(62687132, -), ADediting_1527369(62687133, -), ADediting_1527370(62687146, -), ADediting_1527371(62687194, -), ADediting_1527372(62687199, -), ADediting_1527373(62687219, -), ADediting_1527374(62687229, -), |
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RNA editing positional annotations for LRRN4CL using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_262237 | chr11_62686731_- | UTR3 |
| ADediting_262238 | chr11_62686767_- | UTR3 |
| ADediting_262239 | chr11_62686768_- | UTR3 |
| ADediting_262240 | chr11_62686803_- | UTR3 |
| ADediting_262241 | chr11_62686809_- | UTR3 |
| ADediting_262242 | chr11_62686835_- | UTR3 |
| ADediting_262243 | chr11_62686839_- | UTR3 |
| ADediting_262244 | chr11_62686841_- | UTR3 |
| ADediting_262245 | chr11_62686850_- | UTR3 |
| ADediting_262246 | chr11_62686864_- | UTR3 |
| ADediting_262247 | chr11_62686941_- | UTR3 |
| ADediting_262248 | chr11_62686942_- | UTR3 |
| ADediting_262249 | chr11_62687015_- | UTR3 |
| ADediting_262250 | chr11_62687017_- | UTR3 |
| ADediting_262251 | chr11_62687023_- | UTR3 |
| ADediting_262252 | chr11_62687035_- | UTR3 |
| ADediting_262253 | chr11_62687054_- | UTR3 |
| ADediting_262254 | chr11_62687063_- | UTR3 |
| ADediting_262255 | chr11_62687077_- | UTR3 |
| ADediting_262256 | chr11_62687096_- | UTR3 |
| ADediting_262257 | chr11_62687113_- | UTR3 |
| ADediting_262258 | chr11_62687157_- | UTR3 |
| ADediting_262259 | chr11_62687159_- | UTR3 |
| ADediting_262260 | chr11_62687169_- | UTR3 |
| ADediting_262261 | chr11_62687198_- | UTR3 |
| ADediting_262262 | chr11_62687212_- | UTR3 |
| ADediting_262263 | chr11_62687224_- | UTR3 |
| ADediting_262264 | chr11_62687242_- | UTR3 |
| ADediting_262265 | chr11_62687254_- | UTR3 |
| ADediting_1527357 | chr11_62686782_- | UTR3 |
| ADediting_1527358 | chr11_62686840_- | UTR3 |
| ADediting_1527359 | chr11_62686847_- | UTR3 |
| ADediting_1527360 | chr11_62686849_- | UTR3 |
| ADediting_1527361 | chr11_62686874_- | UTR3 |
| ADediting_1527362 | chr11_62686902_- | UTR3 |
| ADediting_1527363 | chr11_62686911_- | UTR3 |
| ADediting_1527364 | chr11_62686950_- | UTR3 |
| ADediting_1527365 | chr11_62687014_- | UTR3 |
| ADediting_1527366 | chr11_62687036_- | UTR3 |
| ADediting_1527367 | chr11_62687116_- | UTR3 |
| ADediting_1527368 | chr11_62687132_- | UTR3 |
| ADediting_1527369 | chr11_62687133_- | UTR3 |
| ADediting_1527370 | chr11_62687146_- | UTR3 |
| ADediting_1527371 | chr11_62687194_- | UTR3 |
| ADediting_1527372 | chr11_62687199_- | UTR3 |
| ADediting_1527373 | chr11_62687219_- | UTR3 |
| ADediting_1527374 | chr11_62687229_- | UTR3 |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_262237 | chr11_62686731_- | SINE | Alu | Name=AluY |
| ADediting_262238 | chr11_62686767_- | SINE | Alu | Name=AluY |
| ADediting_262239 | chr11_62686768_- | SINE | Alu | Name=AluY |
| ADediting_262240 | chr11_62686803_- | SINE | Alu | Name=AluY |
| ADediting_262241 | chr11_62686809_- | SINE | Alu | Name=AluY |
| ADediting_262242 | chr11_62686835_- | SINE | Alu | Name=AluY |
| ADediting_262243 | chr11_62686839_- | SINE | Alu | Name=AluY |
| ADediting_262244 | chr11_62686841_- | SINE | Alu | Name=AluY |
| ADediting_262245 | chr11_62686850_- | SINE | Alu | Name=AluY |
| ADediting_262246 | chr11_62686864_- | SINE | Alu | Name=AluY |
| ADediting_262247 | chr11_62686941_- | SINE | Alu | Name=AluY |
| ADediting_262248 | chr11_62686942_- | SINE | Alu | Name=AluY |
| ADediting_262249 | chr11_62687015_- | SINE | Alu | Name=AluSx1 |
| ADediting_262250 | chr11_62687017_- | SINE | Alu | Name=AluSx1 |
| ADediting_262251 | chr11_62687023_- | SINE | Alu | Name=AluSx1 |
| ADediting_262252 | chr11_62687035_- | SINE | Alu | Name=AluSx1 |
| ADediting_262253 | chr11_62687054_- | SINE | Alu | Name=AluSx1 |
| ADediting_262254 | chr11_62687063_- | SINE | Alu | Name=AluSx1 |
| ADediting_262255 | chr11_62687077_- | SINE | Alu | Name=AluSx1 |
| ADediting_262256 | chr11_62687096_- | SINE | Alu | Name=AluSx1 |
| ADediting_262257 | chr11_62687113_- | SINE | Alu | Name=AluSx1 |
| ADediting_262258 | chr11_62687157_- | SINE | Alu | Name=AluSx1 |
| ADediting_262259 | chr11_62687159_- | SINE | Alu | Name=AluSx1 |
| ADediting_262260 | chr11_62687169_- | SINE | Alu | Name=AluSx1 |
| ADediting_262261 | chr11_62687198_- | SINE | Alu | Name=AluSx1 |
| ADediting_262262 | chr11_62687212_- | SINE | Alu | Name=AluSx1 |
| ADediting_262263 | chr11_62687224_- | SINE | Alu | Name=AluSx1 |
| ADediting_262264 | chr11_62687242_- | SINE | Alu | Name=AluSx1 |
| ADediting_262265 | chr11_62687254_- | SINE | Alu | Name=AluSx1 |
| ADediting_1527357 | chr11_62686782_- | SINE | Alu | Name=AluY |
| ADediting_1527358 | chr11_62686840_- | SINE | Alu | Name=AluY |
| ADediting_1527359 | chr11_62686847_- | SINE | Alu | Name=AluY |
| ADediting_1527360 | chr11_62686849_- | SINE | Alu | Name=AluY |
| ADediting_1527361 | chr11_62686874_- | SINE | Alu | Name=AluY |
| ADediting_1527362 | chr11_62686902_- | SINE | Alu | Name=AluY |
| ADediting_1527363 | chr11_62686911_- | SINE | Alu | Name=AluY |
| ADediting_1527364 | chr11_62686950_- | SINE | Alu | Name=AluY |
| ADediting_1527365 | chr11_62687014_- | SINE | Alu | Name=AluSx1 |
| ADediting_1527366 | chr11_62687036_- | SINE | Alu | Name=AluSx1 |
| ADediting_1527367 | chr11_62687116_- | SINE | Alu | Name=AluSx1 |
| ADediting_1527368 | chr11_62687132_- | SINE | Alu | Name=AluSx1 |
| ADediting_1527369 | chr11_62687133_- | SINE | Alu | Name=AluSx1 |
| ADediting_1527370 | chr11_62687146_- | SINE | Alu | Name=AluSx1 |
| ADediting_1527371 | chr11_62687194_- | SINE | Alu | Name=AluSx1 |
| ADediting_1527372 | chr11_62687199_- | SINE | Alu | Name=AluSx1 |
| ADediting_1527373 | chr11_62687219_- | SINE | Alu | Name=AluSx1 |
| ADediting_1527374 | chr11_62687229_- | SINE | Alu | Name=AluSx1 |
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RNA A-to-I editing events in the alternative splicing sites for LRRN4CL |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for LRRN4CL |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for LRRN4CL |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for LRRN4CL |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1527358 | chr11_62686840_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-578 | chr11 | 62686838 | 62686844 | 7mer-m8 | 62686837 | 62686857 | 148 | -9.14 |
| ADediting_1527358 | chr11_62686840_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-643 | chr11 | 62686839 | 62686846 | 8mer-1a | 62686839 | 62686861 | 143 | -11.13 |
| ADediting_1527360 | chr11_62686849_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-325 | chr11 | 62686848 | 62686855 | 8mer-1a | 62686848 | 62686870 | 141 | -10.26 |
| ADediting_1527362 | chr11_62686902_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6790-3p | chr11 | 62686898 | 62686905 | 8mer-1a | 62686898 | 62686923 | 147 | -25.27 |
| ADediting_1527364 | chr11_62686950_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-4634 | chr11 | 62686946 | 62686952 | 7mer-m8 | 62686945 | 62686968 | 155 | -34.29 |
| ADediting_1527366 | chr11_62687036_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-3921 | chr11 | 62687034 | 62687040 | 7mer-m8 | 62687033 | 62687055 | 151 | -17.9 |
| ADediting_1527366 | chr11_62687036_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-4653-5p | chr11 | 62687034 | 62687040 | 7mer-m8 | 62687033 | 62687058 | 149 | -19.92 |
| ADediting_1527366 | chr11_62687036_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-4714-5p | chr11 | 62687033 | 62687039 | 7mer-m8 | 62687032 | 62687053 | 144 | -15.09 |
| ADediting_1527366 | chr11_62687036_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6761-5p | chr11 | 62687035 | 62687042 | 8mer-1a | 62687035 | 62687055 | 154 | -22.46 |
| ADediting_1527367 | chr11_62687116_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-3613-3p | chr11 | 62687116 | 62687122 | 7mer-m8 | 62687115 | 62687138 | 147 | -7.57 |
| ADediting_1527368 | chr11_62687132_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-548ae-3p | chr11 | 62687127 | 62687133 | 7mer-m8 | 62687126 | 62687146 | 141 | -10.65 |
| ADediting_1527368 | chr11_62687132_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-548ah-3p | chr11 | 62687127 | 62687133 | 7mer-m8 | 62687126 | 62687148 | 143 | -11.29 |
| ADediting_1527368 | chr11_62687132_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-548aj-3p | chr11 | 62687127 | 62687133 | 7mer-m8 | 62687126 | 62687146 | 141 | -8.54 |
| ADediting_1527368 | chr11_62687132_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-548am-3p | chr11 | 62687127 | 62687133 | 7mer-m8 | 62687126 | 62687148 | 143 | -10.65 |
| ADediting_1527368 | chr11_62687132_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-548aq-3p | chr11 | 62687127 | 62687133 | 7mer-m8 | 62687126 | 62687147 | 141 | -10.72 |
| ADediting_1527368 | chr11_62687132_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-548j-3p | chr11 | 62687127 | 62687133 | 7mer-m8 | 62687126 | 62687146 | 141 | -10.65 |
| ADediting_1527368 | chr11_62687132_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-548x-3p | chr11 | 62687127 | 62687133 | 7mer-m8 | 62687126 | 62687145 | 141 | -8.54 |
| ADediting_1527368 | chr11_62687132_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-7844-5p | chr11 | 62687129 | 62687135 | 7mer-m8 | 62687128 | 62687149 | 160 | -17.71 |
| ADediting_1527369 | chr11_62687133_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-34a-3p | chr11 | 62687130 | 62687136 | 7mer-m8 | 62687129 | 62687151 | 145 | -11.29 |
| ADediting_1527370 | chr11_62687146_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6786-5p | chr11 | 62687146 | 62687152 | 7mer-m8 | 62687145 | 62687166 | 148 | -25.3 |
| ADediting_1527371 | chr11_62687194_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-589-5p | chr11 | 62687189 | 62687195 | 7mer-m8 | 62687188 | 62687209 | 152 | -15.56 |
| ADediting_1527374 | chr11_62687229_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-4537 | chr11 | 62687224 | 62687231 | 8mer-1a | 62687224 | 62687247 | 154 | -24.08 |
| ADediting_262238 | chr11_62686767_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-4284 | chr11 | 62686765 | 62686771 | 7mer-m8 | 62686764 | 62686781 | 148 | -20.34 |
| ADediting_262238 | chr11_62686767_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-4437 | chr11 | 62686764 | 62686770 | 7mer-m8 | 62686763 | 62686783 | 145 | -18.43 |
| ADediting_262241 | chr11_62686809_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-140-3p | chr11 | 62686807 | 62686813 | 7mer-m8 | 62686806 | 62686826 | 156 | -24.57 |
| ADediting_262243 | chr11_62686839_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6844 | chr11 | 62686838 | 62686844 | 7mer-m8 | 62686837 | 62686858 | 155 | -7.49 |
| ADediting_262244 | chr11_62686841_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-4742-3p | chr11 | 62686840 | 62686847 | 8mer-1a | 62686840 | 62686862 | 142 | -9.18 |
| ADediting_262245 | chr11_62686850_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-222-5p | chr11 | 62686848 | 62686855 | 8mer-1a | 62686848 | 62686869 | 140 | -9.13 |
| ADediting_262245 | chr11_62686850_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-30a-3p | chr11 | 62686846 | 62686853 | 8mer-1a | 62686846 | 62686870 | 150 | -12.52 |
| ADediting_262245 | chr11_62686850_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-30d-3p | chr11 | 62686846 | 62686853 | 8mer-1a | 62686846 | 62686868 | 149 | -12.11 |
| ADediting_262245 | chr11_62686850_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-30e-3p | chr11 | 62686846 | 62686853 | 8mer-1a | 62686846 | 62686870 | 150 | -14.55 |
| ADediting_262245 | chr11_62686850_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-936 | chr11 | 62686849 | 62686856 | 8mer-1a | 62686849 | 62686871 | 159 | -22.47 |
| ADediting_262246 | chr11_62686864_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-412-3p | chr11 | 62686864 | 62686870 | 7mer-m8 | 62686863 | 62686885 | 151 | -19.78 |
| ADediting_262246 | chr11_62686864_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-4508 | chr11 | 62686859 | 62686865 | 7mer-m8 | 62686858 | 62686873 | 141 | -24.29 |
| ADediting_262246 | chr11_62686864_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6754-3p | chr11 | 62686864 | 62686870 | 7mer-m8 | 62686863 | 62686883 | 146 | -16.46 |
| ADediting_262247 | chr11_62686941_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-8052 | chr11 | 62686936 | 62686942 | 7mer-1a | 62686936 | 62686954 | 140 | -24.15 |
| ADediting_262248 | chr11_62686942_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-513a-5p | chr11 | 62686941 | 62686947 | 7mer-m8 | 62686940 | 62686957 | 144 | -16.68 |
| ADediting_262248 | chr11_62686942_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-638 | chr11 | 62686936 | 62686942 | 7mer-1a | 62686936 | 62686960 | 159 | -35.56 |
| ADediting_262249 | chr11_62687015_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6847-3p | chr11 | 62687012 | 62687018 | 7mer-m8 | 62687011 | 62687033 | 153 | -22.19 |
| ADediting_262253 | chr11_62687054_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-25-5p | chr11 | 62687052 | 62687058 | 7mer-m8 | 62687051 | 62687072 | 158 | -25.49 |
| ADediting_262253 | chr11_62687054_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-4767 | chr11 | 62687049 | 62687055 | 7mer-m8 | 62687048 | 62687073 | 141 | -23.43 |
| ADediting_262256 | chr11_62687096_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-433-5p | chr11 | 62687095 | 62687101 | 7mer-m8 | 62687094 | 62687117 | 163 | -28.05 |
| ADediting_262261 | chr11_62687198_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6078 | chr11 | 62687194 | 62687201 | 8mer-1a | 62687194 | 62687213 | 148 | -20.43 |
| ADediting_262264 | chr11_62687242_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-18a-3p | chr11 | 62687242 | 62687248 | 7mer-m8 | 62687241 | 62687262 | 141 | -19.11 |
| ADediting_262264 | chr11_62687242_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-324-3p | chr11 | 62687239 | 62687245 | 7mer-m8 | 62687238 | 62687262 | 158 | -25.6 |
| ADediting_262264 | chr11_62687242_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-4252 | chr11 | 62687238 | 62687244 | 7mer-m8 | 62687237 | 62687257 | 142 | -21.65 |
| ADediting_262264 | chr11_62687242_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6890-3p | chr11 | 62687240 | 62687246 | 7mer-m8 | 62687239 | 62687258 | 141 | -20.24 |
| ADediting_262265 | chr11_62687254_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6811-3p | chr11 | 62687252 | 62687258 | 7mer-m8 | 62687251 | 62687271 | 140 | -15.63 |
| ADediting_262265 | chr11_62687254_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6849-3p | chr11 | 62687248 | 62687255 | 8mer-1a | 62687248 | 62687269 | 160 | -23.2 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1527357 | chr11_62686782_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-1976 | chr11 | 62686777 | 62686784 | 8mer-1a | 62686777 | 62686797 | 148 | -21.52 |
| ADediting_1527361 | chr11_62686874_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-3152-3p | chr11 | 62686871 | 62686877 | 7mer-m8 | 62686870 | 62686890 | 145 | -18.08 |
| ADediting_1527364 | chr11_62686950_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6807-5p | chr11 | 62686950 | 62686956 | 7mer-m8 | 62686949 | 62686971 | 144 | -28.04 |
| ADediting_1527373 | chr11_62687219_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6516-5p | chr11 | 62687218 | 62687224 | 7mer-m8 | 62687217 | 62687239 | 149 | -13.64 |
| ADediting_1527374 | chr11_62687229_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-3160-3p | chr11 | 62687224 | 62687231 | 8mer-1a | 62687224 | 62687245 | 150 | -18.87 |
| ADediting_262242 | chr11_62686835_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-4735-5p | chr11 | 62686834 | 62686840 | 7mer-m8 | 62686833 | 62686854 | 140 | -5.48 |
| ADediting_262243 | chr11_62686839_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-4735-5p | chr11 | 62686834 | 62686840 | 7mer-m8 | 62686833 | 62686854 | 140 | -5.48 |
| ADediting_262246 | chr11_62686864_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-193b-5p | chr11 | 62686860 | 62686866 | 7mer-m8 | 62686859 | 62686880 | 142 | -17.8 |
| ADediting_262247 | chr11_62686941_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-10399-5p | chr11 | 62686940 | 62686946 | 7mer-m8 | 62686939 | 62686960 | 144 | -11.2 |
| ADediting_262247 | chr11_62686941_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-5089-5p | chr11 | 62686936 | 62686942 | 7mer-m8 | 62686935 | 62686957 | 148 | -14.13 |
| ADediting_262247 | chr11_62686941_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6504-3p | chr11 | 62686940 | 62686946 | 7mer-m8 | 62686939 | 62686960 | 148 | -14.35 |
| ADediting_262248 | chr11_62686942_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-10399-5p | chr11 | 62686940 | 62686946 | 7mer-m8 | 62686939 | 62686960 | 144 | -11.2 |
| ADediting_262248 | chr11_62686942_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6504-3p | chr11 | 62686940 | 62686946 | 7mer-m8 | 62686939 | 62686960 | 148 | -14.35 |
| ADediting_262248 | chr11_62686942_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-7151-3p | chr11 | 62686941 | 62686948 | 8mer-1a | 62686941 | 62686961 | 144 | -16.51 |
| ADediting_262249 | chr11_62687015_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-4633-5p | chr11 | 62687014 | 62687021 | 8mer-1a | 62687014 | 62687031 | 151 | -15.91 |
| ADediting_262250 | chr11_62687017_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-4633-5p | chr11 | 62687014 | 62687021 | 8mer-1a | 62687014 | 62687031 | 151 | -15.91 |
| ADediting_262250 | chr11_62687017_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6514-3p | chr11 | 62687017 | 62687023 | 7mer-m8 | 62687016 | 62687036 | 155 | -17.54 |
| ADediting_262253 | chr11_62687054_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-363-5p | chr11 | 62687051 | 62687057 | 7mer-m8 | 62687050 | 62687071 | 144 | -20.2 |
| ADediting_262253 | chr11_62687054_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6745 | chr11 | 62687051 | 62687057 | 7mer-m8 | 62687050 | 62687074 | 150 | -25.81 |
| ADediting_262254 | chr11_62687063_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-7162-3p | chr11 | 62687062 | 62687068 | 7mer-m8 | 62687061 | 62687081 | 142 | -17.47 |
| ADediting_262255 | chr11_62687077_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-3672 | chr11 | 62687076 | 62687082 | 7mer-1a | 62687076 | 62687099 | 141 | -13.62 |
| ADediting_262257 | chr11_62687113_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-4684-5p | chr11 | 62687109 | 62687115 | 7mer-m8 | 62687108 | 62687127 | 153 | -15.57 |
| ADediting_262258 | chr11_62687157_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6720-3p | chr11 | 62687152 | 62687158 | 7mer-m8 | 62687151 | 62687175 | 150 | -19.32 |
| ADediting_262260 | chr11_62687169_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-3129-3p | chr11 | 62687166 | 62687172 | 7mer-m8 | 62687165 | 62687183 | 144 | -10.13 |
| ADediting_262260 | chr11_62687169_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-5583-5p | chr11 | 62687166 | 62687172 | 7mer-m8 | 62687165 | 62687185 | 141 | -4.9 |
| ADediting_262262 | chr11_62687212_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-12114 | chr11 | 62687209 | 62687215 | 7mer-m8 | 62687208 | 62687230 | 151 | -21.38 |
| ADediting_262262 | chr11_62687212_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-3689d | chr11 | 62687207 | 62687213 | 7mer-m8 | 62687206 | 62687226 | 150 | -16.17 |
| ADediting_262262 | chr11_62687212_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6134 | chr11 | 62687208 | 62687214 | 7mer-m8 | 62687207 | 62687224 | 151 | -20.09 |
| ADediting_262262 | chr11_62687212_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-6851-5p | chr11 | 62687207 | 62687213 | 7mer-m8 | 62687206 | 62687228 | 147 | -24.94 |
| ADediting_262264 | chr11_62687242_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-4317 | chr11 | 62687240 | 62687246 | 7mer-m8 | 62687239 | 62687255 | 140 | -13.44 |
| ADediting_262265 | chr11_62687254_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-581 | chr11 | 62687253 | 62687259 | 7mer-m8 | 62687252 | 62687272 | 140 | -10.7 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1391023 | chr8_140732605_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-151a-3p | chr11 | 62687342 | 62687348 | 7mer-m8 | 62687341 | 62687360 | 153 | -22.05 |
| ADediting_286380 | chr11_79422188_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-5579-3p | chr11 | 62687010 | 62687016 | 7mer-m8 | 62687009 | 62687034 | 149 | -15.26 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_291761 | chr11_93733708_- | ENSG00000177363.5 | ENST00000317449.5 | LRRN4CL-201 | hsa-miR-1304-3p | chr11 | 62686742 | 62686748 | 7mer-m8 | 62686741 | 62686762 | 151 | -21.2 |
| Differentially expressed gene-miRNA network |
| Differentially expressed mRNA-miRNA network |
 |
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The effects of the RNA editing to the stability of the RNA structures for LRRN4CL |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000317449.5 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_262237 | ENST00000317449.5 | chr11_62686731_- | 1887 | -1094.50 | -1089.10 | -1146.60 |
| ADediting_262238 | ENST00000317449.5 | chr11_62686767_- | 1851 | -1089.10 | -1089.10 | -1146.60 |
| ADediting_262239 | ENST00000317449.5 | chr11_62686768_- | 1850 | -1088.60 | -1089.10 | -1146.60 |
| ADediting_1527357 | ENST00000317449.5 | chr11_62686782_- | 1836 | -1088.40 | -1089.10 | -1146.60 |
| ADediting_262240 | ENST00000317449.5 | chr11_62686803_- | 1815 | -1088.30 | -1089.10 | -1146.60 |
| ADediting_262241 | ENST00000317449.5 | chr11_62686809_- | 1809 | -1088.70 | -1089.10 | -1146.60 |
| ADediting_262242 | ENST00000317449.5 | chr11_62686835_- | 1783 | -1088.80 | -1089.10 | -1146.60 |
| ADediting_262243 | ENST00000317449.5 | chr11_62686839_- | 1779 | -1089.20 | -1089.10 | -1146.60 |
| ADediting_1527358 | ENST00000317449.5 | chr11_62686840_- | 1778 | -1089.20 | -1089.10 | -1146.60 |
| ADediting_262244 | ENST00000317449.5 | chr11_62686841_- | 1777 | -1089.20 | -1089.10 | -1146.60 |
| ADediting_1527359 | ENST00000317449.5 | chr11_62686847_- | 1771 | -1089.50 | -1089.10 | -1146.60 |
| ADediting_1527360 | ENST00000317449.5 | chr11_62686849_- | 1769 | -1089.50 | -1089.10 | -1146.60 |
| ADediting_262245 | ENST00000317449.5 | chr11_62686850_- | 1768 | -1089.20 | -1089.10 | -1146.60 |
| ADediting_262246 | ENST00000317449.5 | chr11_62686864_- | 1754 | -1089.10 | -1089.10 | -1146.60 |
| ADediting_1527361 | ENST00000317449.5 | chr11_62686874_- | 1744 | -1089.10 | -1089.10 | -1146.60 |
| ADediting_1527362 | ENST00000317449.5 | chr11_62686902_- | 1716 | -1095.70 | -1089.10 | -1146.60 |
| ADediting_1527363 | ENST00000317449.5 | chr11_62686911_- | 1707 | -1093.70 | -1089.10 | -1146.60 |
| ADediting_262247 | ENST00000317449.5 | chr11_62686941_- | 1677 | -1089.10 | -1089.10 | -1146.60 |
| ADediting_262248 | ENST00000317449.5 | chr11_62686942_- | 1676 | -1089.20 | -1089.10 | -1146.60 |
| ADediting_1527364 | ENST00000317449.5 | chr11_62686950_- | 1668 | -1089.40 | -1089.10 | -1146.60 |
| ADediting_1527365 | ENST00000317449.5 | chr11_62687014_- | 1604 | -1089.10 | -1089.10 | -1146.60 |
| ADediting_262249 | ENST00000317449.5 | chr11_62687015_- | 1603 | -1095.10 | -1089.10 | -1146.60 |
| ADediting_262250 | ENST00000317449.5 | chr11_62687017_- | 1601 | -1094.50 | -1089.10 | -1146.60 |
| ADediting_262251 | ENST00000317449.5 | chr11_62687023_- | 1595 | -1089.10 | -1089.10 | -1146.60 |
| ADediting_262252 | ENST00000317449.5 | chr11_62687035_- | 1583 | -1088.80 | -1089.10 | -1146.60 |
| ADediting_1527366 | ENST00000317449.5 | chr11_62687036_- | 1582 | -1089.20 | -1089.10 | -1146.60 |
| ADediting_262253 | ENST00000317449.5 | chr11_62687054_- | 1564 | -1092.90 | -1089.10 | -1146.60 |
| ADediting_262254 | ENST00000317449.5 | chr11_62687063_- | 1555 | -1093.30 | -1089.10 | -1146.60 |
| ADediting_262255 | ENST00000317449.5 | chr11_62687077_- | 1541 | -1094.70 | -1089.10 | -1146.60 |
| ADediting_262256 | ENST00000317449.5 | chr11_62687096_- | 1522 | -1094.90 | -1089.10 | -1146.60 |
| ADediting_262257 | ENST00000317449.5 | chr11_62687113_- | 1505 | -1088.80 | -1089.10 | -1146.60 |
| ADediting_1527367 | ENST00000317449.5 | chr11_62687116_- | 1502 | -1088.80 | -1089.10 | -1146.60 |
| ADediting_1527368 | ENST00000317449.5 | chr11_62687132_- | 1486 | -1089.10 | -1089.10 | -1146.60 |
| ADediting_1527369 | ENST00000317449.5 | chr11_62687133_- | 1485 | -1089.20 | -1089.10 | -1146.60 |
| ADediting_1527370 | ENST00000317449.5 | chr11_62687146_- | 1472 | -1088.70 | -1089.10 | -1146.60 |
| ADediting_262258 | ENST00000317449.5 | chr11_62687157_- | 1461 | -1088.40 | -1089.10 | -1146.60 |
| ADediting_262259 | ENST00000317449.5 | chr11_62687159_- | 1459 | -1089.10 | -1089.10 | -1146.60 |
| ADediting_262260 | ENST00000317449.5 | chr11_62687169_- | 1449 | -1088.80 | -1089.10 | -1146.60 |
| ADediting_1527371 | ENST00000317449.5 | chr11_62687194_- | 1424 | -1089.40 | -1089.10 | -1146.60 |
| ADediting_262261 | ENST00000317449.5 | chr11_62687198_- | 1420 | -1091.70 | -1089.10 | -1146.60 |
| ADediting_1527372 | ENST00000317449.5 | chr11_62687199_- | 1419 | -1089.80 | -1089.10 | -1146.60 |
| ADediting_262262 | ENST00000317449.5 | chr11_62687212_- | 1406 | -1094.50 | -1089.10 | -1146.60 |
| ADediting_1527373 | ENST00000317449.5 | chr11_62687219_- | 1399 | -1088.80 | -1089.10 | -1146.60 |
| ADediting_262263 | ENST00000317449.5 | chr11_62687224_- | 1394 | -1088.70 | -1089.10 | -1146.60 |
| ADediting_1527374 | ENST00000317449.5 | chr11_62687229_- | 1389 | -1091.00 | -1089.10 | -1146.60 |
| ADediting_262264 | ENST00000317449.5 | chr11_62687242_- | 1376 | -1095.30 | -1089.10 | -1146.60 |
| ADediting_262265 | ENST00000317449.5 | chr11_62687254_- | 1364 | -1095.70 | -1089.10 | -1146.60 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for LRRN4CL |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 4.06538619957658e-06 | 0.258306033653086 | 0.176833774701621 | 0.0769041536840138 | 6.30393021364229e-31 | 0.593818485383316 |
| PCC | 1.08469610680396e-18 | 0.581790818065567 | 1.40590555179942e-17 | 0.566119576825999 | 0.476079774758749 | 0.0518692704235132 |
| CER | 0.0292050621072006 | 0.178117729780755 | 1.25618996369896e-05 | 0.348295578458513 | 0.160897397041912 | 0.115059659989529 |
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Relation with AD stages for LRRN4CL |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
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RelatedDrugs for LRRN4CL |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for LRRN4CL |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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