|
||||||
|
 | |
| |
| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
| |
| |
| The effects of the RNA editing to the stability of the RNA structures |
| |
| |
| |
|
Gene summary for AKT2 |
 Gene summary |
| Gene information | Gene symbol | AKT2 | Gene ID | 208 |
| Gene name | AKT serine/threonine kinase 2 | |
| Synonyms | HIHGHH|PKBB|PKBBETA|PRKBB|RAC-BETA | |
| Cytomap | 19q13.2 | |
| Type of gene | protein-coding | |
| Description | RAC-beta serine/threonine-protein kinasePKB betaRAC-PK-betamurine thymoma viral (v-akt) homolog-2protein kinase Akt-2protein kinase B betaputative v-akt murine thymoma viral oncoprotein 2rac protein kinase betav-akt murine thymoma viral oncogene h | |
| Modification date | 20200313 | |
| UniProtAcc | P31751, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| AKT2 | GO:0030335 | positive regulation of cell migration | 25428377 |
Top |
RNA A-to-I events for AKT2 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_750419(40230788, -), ADediting_750420(40230808, -), ADediting_750421(40230813, -), ADediting_750422(40230818, -), ADediting_750423(40230823, -), ADediting_750424(40230842, -), ADediting_750425(40230859, -), ADediting_750426(40230860, -), ADediting_750428(40230878, -), ADediting_750429(40230886, -), ADediting_750430(40230890, -), ADediting_750431(40230891, -), ADediting_750432(40230895, -), ADediting_750433(40230898, -), ADediting_750434(40230899, -), ADediting_750435(40230901, -), ADediting_750436(40230902, -), ADediting_750437(40230904, -), ADediting_750438(40230918, -), ADediting_750439(40230922, -), ADediting_750440(40230986, -), ADediting_750441(40230990, -), ADediting_750442(40230995, -), ADediting_750443(40230996, -), ADediting_750452(40240794, -), ADediting_750453(40240925, -), ADediting_750454(40240941, -), ADediting_750455(40244208, -), ADediting_750456(40244358, -), ADediting_750457(40246245, -), ADediting_750458(40246262, -), ADediting_750459(40246272, -), ADediting_750460(40246319, -), ADediting_750461(40246396, -), ADediting_750462(40246397, -), ADediting_750463(40246403, -), ADediting_750464(40246410, -), ADediting_750471(40254353, -), ADediting_750472(40254416, -), ADediting_750473(40254420, -), ADediting_750495(40266392, -), ADediting_750496(40266940, -), ADediting_750502(40268870, -), ADediting_750503(40268954, -), ADediting_750504(40269044, -), ADediting_750505(40269053, -), ADediting_750507(40270594, -), ADediting_750508(40270778, -), ADediting_750509(40271303, -), ADediting_750510(40271351, -), ADediting_750511(40271364, -), ADediting_750512(40271375, -), ADediting_750513(40271381, -), ADediting_750514(40271383, -), ADediting_750517(40275821, -), ADediting_750518(40275833, -), ADediting_750519(40275847, -), ADediting_750520(40275850, -), ADediting_750521(40275864, -), ADediting_750522(40275889, -), ADediting_750523(40275913, -), ADediting_750524(40275929, -), ADediting_750525(40275930, -), ADediting_750526(40275949, -), ADediting_750527(40275952, -), ADediting_750528(40276418, -), ADediting_750529(40276426, -), ADediting_750530(40276431, -), ADediting_750531(40276433, -), ADediting_750532(40276434, -), ADediting_750533(40276438, -), ADediting_750534(40276442, -), ADediting_750535(40276449, -), ADediting_750536(40276451, -), ADediting_750537(40276454, -), ADediting_750538(40276455, -), ADediting_750539(40276462, -), ADediting_750540(40276463, -), ADediting_750541(40276471, -), ADediting_750542(40276472, -), ADediting_750543(40276477, -), ADediting_750544(40276481, -), ADediting_750545(40276487, -), ADediting_750546(40276494, -), ADediting_750547(40276498, -), ADediting_750548(40276503, -), ADediting_750549(40276504, -), ADediting_750550(40276506, -), ADediting_750551(40276526, -), ADediting_750552(40276530, -), ADediting_750553(40276533, -), ADediting_750554(40276534, -), ADediting_750555(40276535, -), ADediting_750556(40276536, -), ADediting_750557(40276539, -), ADediting_750558(40276541, -), ADediting_750559(40276542, -), ADediting_750560(40276543, -), ADediting_750561(40276544, -), ADediting_750562(40276545, -), ADediting_750563(40276548, -), ADediting_750564(40276559, -), ADediting_750565(40276560, -), ADediting_750566(40276569, -), ADediting_750567(40276570, -), ADediting_750568(40276579, -), ADediting_750569(40276585, -), ADediting_750570(40276593, -), ADediting_750571(40276598, -), ADediting_750572(40276601, -), ADediting_750573(40276611, -), ADediting_750574(40276628, -), ADediting_750575(40276636, -), ADediting_750576(40276637, -), ADediting_750577(40276643, -), ADediting_750578(40276645, -), ADediting_750579(40276655, -), ADediting_750580(40276666, -), ADediting_750581(40276741, -), ADediting_750582(40276750, -), ADediting_750583(40276759, -), ADediting_750584(40276771, -), ADediting_750585(40276772, -), ADediting_750586(40276781, -), ADediting_750587(40276811, -), ADediting_750588(40276818, -), ADediting_750589(40276824, -), ADediting_750590(40276849, -), ADediting_750591(40276851, -), ADediting_750592(40276854, -), ADediting_750593(40276895, -), ADediting_750594(40276899, -), ADediting_750595(40276901, -), ADediting_750596(40276904, -), ADediting_750597(40276911, -), ADediting_750598(40276923, -), ADediting_750599(40276928, -), ADediting_750600(40276954, -), ADediting_750601(40276973, -), ADediting_750602(40276979, -), ADediting_750603(40276985, -), ADediting_750604(40276989, -), ADediting_750605(40276997, -), ADediting_750606(40277001, -), ADediting_750607(40277017, -), ADediting_750608(40277021, -), ADediting_750610(40281368, -), ADediting_750611(40281370, -), ADediting_750612(40281397, -), ADediting_750613(40281423, -), ADediting_750614(40282629, -), ADediting_750615(40282633, -), ADediting_750616(40282634, -), ADediting_750617(40282676, -), ADediting_750618(40283417, -), ADediting_750619(40284063, -), ADediting_750620(40284237, -), ADediting_750621(40284344, -), ADediting_1556044(40230987, -), ADediting_1556046(40241061, -), ADediting_1556047(40244332, -), ADediting_1556048(40246329, -), ADediting_1556049(40246366, -), ADediting_1556051(40250716, -), ADediting_1556052(40254802, -), ADediting_1556053(40270840, -), ADediting_1556054(40270961, -), ADediting_1556060(40275742, -), ADediting_1556061(40276537, -), ADediting_1556062(40276561, -), ADediting_1556063(40276888, -), ADediting_1556064(40276891, -), ADediting_1556065(40281294, -), ADediting_1556066(40282618, -), ADediting_1556067(40282625, -), ADediting_1631457(40250341, -), ADediting_1631458(40282624, -), |
Top |
RNA editing positional annotations for AKT2 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_750419 | chr19_40230788_- | UTR3 |
| ADediting_750420 | chr19_40230808_- | UTR3 |
| ADediting_750421 | chr19_40230813_- | UTR3 |
| ADediting_750422 | chr19_40230818_- | UTR3 |
| ADediting_750423 | chr19_40230823_- | UTR3 |
| ADediting_750424 | chr19_40230842_- | UTR3 |
| ADediting_750425 | chr19_40230859_- | UTR3 |
| ADediting_750426 | chr19_40230860_- | UTR3 |
| ADediting_750428 | chr19_40230878_- | UTR3 |
| ADediting_750429 | chr19_40230886_- | UTR3 |
| ADediting_750430 | chr19_40230890_- | UTR3 |
| ADediting_750431 | chr19_40230891_- | UTR3 |
| ADediting_750432 | chr19_40230895_- | UTR3 |
| ADediting_750433 | chr19_40230898_- | UTR3 |
| ADediting_750434 | chr19_40230899_- | UTR3 |
| ADediting_750435 | chr19_40230901_- | UTR3 |
| ADediting_750436 | chr19_40230902_- | UTR3 |
| ADediting_750437 | chr19_40230904_- | UTR3 |
| ADediting_750438 | chr19_40230918_- | UTR3 |
| ADediting_750439 | chr19_40230922_- | UTR3 |
| ADediting_750440 | chr19_40230986_- | UTR3 |
| ADediting_750441 | chr19_40230990_- | UTR3 |
| ADediting_750442 | chr19_40230995_- | UTR3 |
| ADediting_750443 | chr19_40230996_- | UTR3 |
| ADediting_750452 | chr19_40240794_- | intronic |
| ADediting_750453 | chr19_40240925_- | intronic |
| ADediting_750454 | chr19_40240941_- | intronic |
| ADediting_750455 | chr19_40244208_- | intronic |
| ADediting_750456 | chr19_40244358_- | UTR3 |
| ADediting_750457 | chr19_40246245_- | intronic |
| ADediting_750458 | chr19_40246262_- | intronic |
| ADediting_750459 | chr19_40246272_- | intronic |
| ADediting_750460 | chr19_40246319_- | intronic |
| ADediting_750461 | chr19_40246396_- | intronic |
| ADediting_750462 | chr19_40246397_- | intronic |
| ADediting_750463 | chr19_40246403_- | intronic |
| ADediting_750464 | chr19_40246410_- | intronic |
| ADediting_750471 | chr19_40254353_- | intronic |
| ADediting_750472 | chr19_40254416_- | intronic |
| ADediting_750473 | chr19_40254420_- | intronic |
| ADediting_750495 | chr19_40266392_- | intronic |
| ADediting_750496 | chr19_40266940_- | intronic |
| ADediting_750502 | chr19_40268870_- | intronic |
| ADediting_750503 | chr19_40268954_- | intronic |
| ADediting_750504 | chr19_40269044_- | intronic |
| ADediting_750505 | chr19_40269053_- | intronic |
| ADediting_750507 | chr19_40270594_- | UTR5 |
| ADediting_750508 | chr19_40270778_- | intronic |
| ADediting_750509 | chr19_40271303_- | intronic |
| ADediting_750510 | chr19_40271351_- | intronic |
| ADediting_750511 | chr19_40271364_- | intronic |
| ADediting_750512 | chr19_40271375_- | intronic |
| ADediting_750513 | chr19_40271381_- | intronic |
| ADediting_750514 | chr19_40271383_- | intronic |
| ADediting_750517 | chr19_40275821_- | intronic |
| ADediting_750518 | chr19_40275833_- | intronic |
| ADediting_750519 | chr19_40275847_- | intronic |
| ADediting_750520 | chr19_40275850_- | intronic |
| ADediting_750521 | chr19_40275864_- | intronic |
| ADediting_750522 | chr19_40275889_- | intronic |
| ADediting_750523 | chr19_40275913_- | intronic |
| ADediting_750524 | chr19_40275929_- | intronic |
| ADediting_750525 | chr19_40275930_- | intronic |
| ADediting_750526 | chr19_40275949_- | intronic |
| ADediting_750527 | chr19_40275952_- | intronic |
| ADediting_750528 | chr19_40276418_- | intronic |
| ADediting_750529 | chr19_40276426_- | intronic |
| ADediting_750530 | chr19_40276431_- | intronic |
| ADediting_750531 | chr19_40276433_- | intronic |
| ADediting_750532 | chr19_40276434_- | intronic |
| ADediting_750533 | chr19_40276438_- | intronic |
| ADediting_750534 | chr19_40276442_- | intronic |
| ADediting_750535 | chr19_40276449_- | intronic |
| ADediting_750536 | chr19_40276451_- | intronic |
| ADediting_750537 | chr19_40276454_- | intronic |
| ADediting_750538 | chr19_40276455_- | intronic |
| ADediting_750539 | chr19_40276462_- | intronic |
| ADediting_750540 | chr19_40276463_- | intronic |
| ADediting_750541 | chr19_40276471_- | intronic |
| ADediting_750542 | chr19_40276472_- | intronic |
| ADediting_750543 | chr19_40276477_- | intronic |
| ADediting_750544 | chr19_40276481_- | intronic |
| ADediting_750545 | chr19_40276487_- | intronic |
| ADediting_750546 | chr19_40276494_- | intronic |
| ADediting_750547 | chr19_40276498_- | intronic |
| ADediting_750548 | chr19_40276503_- | intronic |
| ADediting_750549 | chr19_40276504_- | intronic |
| ADediting_750550 | chr19_40276506_- | intronic |
| ADediting_750551 | chr19_40276526_- | intronic |
| ADediting_750552 | chr19_40276530_- | intronic |
| ADediting_750553 | chr19_40276533_- | intronic |
| ADediting_750554 | chr19_40276534_- | intronic |
| ADediting_750555 | chr19_40276535_- | intronic |
| ADediting_750556 | chr19_40276536_- | intronic |
| ADediting_750557 | chr19_40276539_- | intronic |
| ADediting_750558 | chr19_40276541_- | intronic |
| ADediting_750559 | chr19_40276542_- | intronic |
| ADediting_750560 | chr19_40276543_- | intronic |
| ADediting_750561 | chr19_40276544_- | intronic |
| ADediting_750562 | chr19_40276545_- | intronic |
| ADediting_750563 | chr19_40276548_- | intronic |
| ADediting_750564 | chr19_40276559_- | intronic |
| ADediting_750565 | chr19_40276560_- | intronic |
| ADediting_750566 | chr19_40276569_- | intronic |
| ADediting_750567 | chr19_40276570_- | intronic |
| ADediting_750568 | chr19_40276579_- | intronic |
| ADediting_750569 | chr19_40276585_- | intronic |
| ADediting_750570 | chr19_40276593_- | intronic |
| ADediting_750571 | chr19_40276598_- | intronic |
| ADediting_750572 | chr19_40276601_- | intronic |
| ADediting_750573 | chr19_40276611_- | intronic |
| ADediting_750574 | chr19_40276628_- | intronic |
| ADediting_750575 | chr19_40276636_- | intronic |
| ADediting_750576 | chr19_40276637_- | intronic |
| ADediting_750577 | chr19_40276643_- | intronic |
| ADediting_750578 | chr19_40276645_- | intronic |
| ADediting_750579 | chr19_40276655_- | intronic |
| ADediting_750580 | chr19_40276666_- | intronic |
| ADediting_750581 | chr19_40276741_- | intronic |
| ADediting_750582 | chr19_40276750_- | intronic |
| ADediting_750583 | chr19_40276759_- | intronic |
| ADediting_750584 | chr19_40276771_- | intronic |
| ADediting_750585 | chr19_40276772_- | intronic |
| ADediting_750586 | chr19_40276781_- | intronic |
| ADediting_750587 | chr19_40276811_- | intronic |
| ADediting_750588 | chr19_40276818_- | intronic |
| ADediting_750589 | chr19_40276824_- | intronic |
| ADediting_750590 | chr19_40276849_- | intronic |
| ADediting_750591 | chr19_40276851_- | intronic |
| ADediting_750592 | chr19_40276854_- | intronic |
| ADediting_750593 | chr19_40276895_- | intronic |
| ADediting_750594 | chr19_40276899_- | intronic |
| ADediting_750595 | chr19_40276901_- | intronic |
| ADediting_750596 | chr19_40276904_- | intronic |
| ADediting_750597 | chr19_40276911_- | intronic |
| ADediting_750598 | chr19_40276923_- | intronic |
| ADediting_750599 | chr19_40276928_- | intronic |
| ADediting_750600 | chr19_40276954_- | intronic |
| ADediting_750601 | chr19_40276973_- | intronic |
| ADediting_750602 | chr19_40276979_- | intronic |
| ADediting_750603 | chr19_40276985_- | intronic |
| ADediting_750604 | chr19_40276989_- | intronic |
| ADediting_750605 | chr19_40276997_- | intronic |
| ADediting_750606 | chr19_40277001_- | intronic |
| ADediting_750607 | chr19_40277017_- | intronic |
| ADediting_750608 | chr19_40277021_- | intronic |
| ADediting_750610 | chr19_40281368_- | intronic |
| ADediting_750611 | chr19_40281370_- | intronic |
| ADediting_750612 | chr19_40281397_- | intronic |
| ADediting_750613 | chr19_40281423_- | intronic |
| ADediting_750614 | chr19_40282629_- | ncRNA_exonic |
| ADediting_750615 | chr19_40282633_- | ncRNA_exonic |
| ADediting_750616 | chr19_40282634_- | ncRNA_exonic |
| ADediting_750617 | chr19_40282676_- | intronic |
| ADediting_750618 | chr19_40283417_- | intronic |
| ADediting_750619 | chr19_40284063_- | intronic |
| ADediting_750620 | chr19_40284237_- | intronic |
| ADediting_750621 | chr19_40284344_- | intronic |
| ADediting_1556044 | chr19_40230987_- | UTR3 |
| ADediting_1556046 | chr19_40241061_- | intronic |
| ADediting_1556047 | chr19_40244332_- | UTR3 |
| ADediting_1556048 | chr19_40246329_- | intronic |
| ADediting_1556049 | chr19_40246366_- | intronic |
| ADediting_1556051 | chr19_40250716_- | intronic |
| ADediting_1556052 | chr19_40254802_- | intronic |
| ADediting_1556053 | chr19_40270840_- | intronic |
| ADediting_1556054 | chr19_40270961_- | intronic |
| ADediting_1556060 | chr19_40275742_- | intronic |
| ADediting_1556061 | chr19_40276537_- | intronic |
| ADediting_1556062 | chr19_40276561_- | intronic |
| ADediting_1556063 | chr19_40276888_- | intronic |
| ADediting_1556064 | chr19_40276891_- | intronic |
| ADediting_1556065 | chr19_40281294_- | intronic |
| ADediting_1556066 | chr19_40282618_- | ncRNA_exonic |
| ADediting_1556067 | chr19_40282625_- | ncRNA_exonic |
| ADediting_1631457 | chr19_40250341_- | intronic |
| ADediting_1631458 | chr19_40282624_- | ncRNA_exonic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_750419 | chr19_40230788_- | SINE | Alu | Name=AluJr |
| ADediting_750420 | chr19_40230808_- | SINE | Alu | Name=AluJr |
| ADediting_750421 | chr19_40230813_- | SINE | Alu | Name=AluJr |
| ADediting_750422 | chr19_40230818_- | SINE | Alu | Name=AluJr |
| ADediting_750423 | chr19_40230823_- | SINE | Alu | Name=AluJr |
| ADediting_750424 | chr19_40230842_- | SINE | Alu | Name=AluJr |
| ADediting_750425 | chr19_40230859_- | SINE | Alu | Name=AluJr |
| ADediting_750426 | chr19_40230860_- | SINE | Alu | Name=AluJr |
| ADediting_750428 | chr19_40230878_- | SINE | Alu | Name=AluJr |
| ADediting_750429 | chr19_40230886_- | SINE | Alu | Name=AluJr |
| ADediting_750430 | chr19_40230890_- | SINE | Alu | Name=AluJr |
| ADediting_750431 | chr19_40230891_- | SINE | Alu | Name=AluJr |
| ADediting_750432 | chr19_40230895_- | SINE | Alu | Name=AluJr |
| ADediting_750433 | chr19_40230898_- | SINE | Alu | Name=AluJr |
| ADediting_750434 | chr19_40230899_- | SINE | Alu | Name=AluJr |
| ADediting_750435 | chr19_40230901_- | SINE | Alu | Name=AluJr |
| ADediting_750436 | chr19_40230902_- | SINE | Alu | Name=AluJr |
| ADediting_750437 | chr19_40230904_- | SINE | Alu | Name=AluJr |
| ADediting_750438 | chr19_40230918_- | SINE | Alu | Name=AluJr |
| ADediting_750439 | chr19_40230922_- | SINE | Alu | Name=AluJr |
| ADediting_750440 | chr19_40230986_- | SINE | Alu | Name=AluJr |
| ADediting_750441 | chr19_40230990_- | SINE | Alu | Name=AluJr |
| ADediting_750442 | chr19_40230995_- | SINE | Alu | Name=AluJr |
| ADediting_750443 | chr19_40230996_- | SINE | Alu | Name=AluJr |
| ADediting_750452 | chr19_40240794_- | SINE | Alu | Name=AluJo |
| ADediting_750453 | chr19_40240925_- | SINE | Alu | Name=AluJo |
| ADediting_750454 | chr19_40240941_- | SINE | Alu | Name=AluJo |
| ADediting_750455 | chr19_40244208_- | SINE | Alu | Name=AluJr |
| ADediting_750456 | chr19_40244358_- | SINE | Alu | Name=AluJr |
| ADediting_750457 | chr19_40246245_- | SINE | Alu | Name=AluSc |
| ADediting_750458 | chr19_40246262_- | SINE | Alu | Name=AluSc |
| ADediting_750459 | chr19_40246272_- | SINE | Alu | Name=AluSc |
| ADediting_750460 | chr19_40246319_- | SINE | Alu | Name=AluSc |
| ADediting_750461 | chr19_40246396_- | SINE | Alu | Name=AluSc |
| ADediting_750462 | chr19_40246397_- | SINE | Alu | Name=AluSc |
| ADediting_750463 | chr19_40246403_- | SINE | Alu | Name=AluSc |
| ADediting_750464 | chr19_40246410_- | SINE | Alu | Name=AluSc |
| ADediting_750471 | chr19_40254353_- | SINE | Alu | Name=AluSx |
| ADediting_750472 | chr19_40254416_- | SINE | Alu | Name=AluSx |
| ADediting_750473 | chr19_40254420_- | SINE | Alu | Name=AluSx |
| ADediting_750496 | chr19_40266940_- | SINE | Alu | Name=AluJb |
| ADediting_750502 | chr19_40268870_- | SINE | Alu | Name=AluSp |
| ADediting_750503 | chr19_40268954_- | SINE | Alu | Name=AluSp |
| ADediting_750504 | chr19_40269044_- | SINE | Alu | Name=AluSp |
| ADediting_750505 | chr19_40269053_- | SINE | Alu | Name=AluSp |
| ADediting_750508 | chr19_40270778_- | SINE | Alu | Name=AluJr |
| ADediting_750509 | chr19_40271303_- | SINE | Alu | Name=AluJb |
| ADediting_750510 | chr19_40271351_- | SINE | Alu | Name=AluJb |
| ADediting_750511 | chr19_40271364_- | SINE | Alu | Name=AluJb |
| ADediting_750512 | chr19_40271375_- | SINE | Alu | Name=AluJb |
| ADediting_750513 | chr19_40271381_- | SINE | Alu | Name=AluJb |
| ADediting_750514 | chr19_40271383_- | SINE | Alu | Name=AluJb |
| ADediting_750517 | chr19_40275821_- | SINE | Alu | Name=AluSg7 |
| ADediting_750518 | chr19_40275833_- | SINE | Alu | Name=AluSg7 |
| ADediting_750519 | chr19_40275847_- | SINE | Alu | Name=AluSg7 |
| ADediting_750520 | chr19_40275850_- | SINE | Alu | Name=AluSg7 |
| ADediting_750521 | chr19_40275864_- | SINE | Alu | Name=AluSg7 |
| ADediting_750522 | chr19_40275889_- | SINE | Alu | Name=AluSg7 |
| ADediting_750523 | chr19_40275913_- | SINE | Alu | Name=AluSg7 |
| ADediting_750524 | chr19_40275929_- | SINE | Alu | Name=AluSg7 |
| ADediting_750525 | chr19_40275930_- | SINE | Alu | Name=AluSg7 |
| ADediting_750526 | chr19_40275949_- | SINE | Alu | Name=AluSg7 |
| ADediting_750527 | chr19_40275952_- | SINE | Alu | Name=AluSg7 |
| ADediting_750528 | chr19_40276418_- | SINE | Alu | Name=AluSg7 |
| ADediting_750529 | chr19_40276426_- | SINE | Alu | Name=AluSg7 |
| ADediting_750530 | chr19_40276431_- | SINE | Alu | Name=AluSg7 |
| ADediting_750531 | chr19_40276433_- | SINE | Alu | Name=AluSg7 |
| ADediting_750532 | chr19_40276434_- | SINE | Alu | Name=AluSg7 |
| ADediting_750533 | chr19_40276438_- | SINE | Alu | Name=AluSg7 |
| ADediting_750534 | chr19_40276442_- | SINE | Alu | Name=AluSg7 |
| ADediting_750535 | chr19_40276449_- | SINE | Alu | Name=AluSg7 |
| ADediting_750536 | chr19_40276451_- | SINE | Alu | Name=AluSg7 |
| ADediting_750537 | chr19_40276454_- | SINE | Alu | Name=AluSg7 |
| ADediting_750538 | chr19_40276455_- | SINE | Alu | Name=AluSg7 |
| ADediting_750539 | chr19_40276462_- | SINE | Alu | Name=AluSg7 |
| ADediting_750540 | chr19_40276463_- | SINE | Alu | Name=AluSg7 |
| ADediting_750541 | chr19_40276471_- | SINE | Alu | Name=AluSg7 |
| ADediting_750542 | chr19_40276472_- | SINE | Alu | Name=AluSg7 |
| ADediting_750543 | chr19_40276477_- | SINE | Alu | Name=AluSg7 |
| ADediting_750544 | chr19_40276481_- | SINE | Alu | Name=AluSg7 |
| ADediting_750545 | chr19_40276487_- | SINE | Alu | Name=AluSg7 |
| ADediting_750546 | chr19_40276494_- | SINE | Alu | Name=AluSg7 |
| ADediting_750547 | chr19_40276498_- | SINE | Alu | Name=AluSg7 |
| ADediting_750548 | chr19_40276503_- | SINE | Alu | Name=AluSg7 |
| ADediting_750549 | chr19_40276504_- | SINE | Alu | Name=AluSg7 |
| ADediting_750550 | chr19_40276506_- | SINE | Alu | Name=AluSg7 |
| ADediting_750551 | chr19_40276526_- | SINE | Alu | Name=AluSg7 |
| ADediting_750552 | chr19_40276530_- | SINE | Alu | Name=AluSg7 |
| ADediting_750553 | chr19_40276533_- | SINE | Alu | Name=AluSg7 |
| ADediting_750554 | chr19_40276534_- | SINE | Alu | Name=AluSg7 |
| ADediting_750555 | chr19_40276535_- | SINE | Alu | Name=AluSg7 |
| ADediting_750556 | chr19_40276536_- | SINE | Alu | Name=AluSg7 |
| ADediting_750557 | chr19_40276539_- | SINE | Alu | Name=AluSg7 |
| ADediting_750558 | chr19_40276541_- | SINE | Alu | Name=AluSg7 |
| ADediting_750559 | chr19_40276542_- | SINE | Alu | Name=AluSg7 |
| ADediting_750560 | chr19_40276543_- | SINE | Alu | Name=AluSg7 |
| ADediting_750561 | chr19_40276544_- | SINE | Alu | Name=AluSg7 |
| ADediting_750562 | chr19_40276545_- | SINE | Alu | Name=AluSg7 |
| ADediting_750563 | chr19_40276548_- | SINE | Alu | Name=AluSg7 |
| ADediting_750564 | chr19_40276559_- | SINE | Alu | Name=AluSg7 |
| ADediting_750565 | chr19_40276560_- | SINE | Alu | Name=AluSg7 |
| ADediting_750566 | chr19_40276569_- | SINE | Alu | Name=AluSg7 |
| ADediting_750567 | chr19_40276570_- | SINE | Alu | Name=AluSg7 |
| ADediting_750568 | chr19_40276579_- | SINE | Alu | Name=AluSg7 |
| ADediting_750569 | chr19_40276585_- | SINE | Alu | Name=AluSg7 |
| ADediting_750570 | chr19_40276593_- | SINE | Alu | Name=AluSg7 |
| ADediting_750571 | chr19_40276598_- | SINE | Alu | Name=AluSg7 |
| ADediting_750572 | chr19_40276601_- | SINE | Alu | Name=AluSg7 |
| ADediting_750573 | chr19_40276611_- | SINE | Alu | Name=AluSg7 |
| ADediting_750574 | chr19_40276628_- | SINE | Alu | Name=AluSg7 |
| ADediting_750575 | chr19_40276636_- | SINE | Alu | Name=AluSg7 |
| ADediting_750576 | chr19_40276637_- | SINE | Alu | Name=AluSg7 |
| ADediting_750577 | chr19_40276643_- | SINE | Alu | Name=AluSg7 |
| ADediting_750578 | chr19_40276645_- | SINE | Alu | Name=AluSg7 |
| ADediting_750579 | chr19_40276655_- | SINE | Alu | Name=AluSg7 |
| ADediting_750581 | chr19_40276741_- | SINE | Alu | Name=AluJb |
| ADediting_750582 | chr19_40276750_- | SINE | Alu | Name=AluJb |
| ADediting_750583 | chr19_40276759_- | SINE | Alu | Name=AluJb |
| ADediting_750584 | chr19_40276771_- | SINE | Alu | Name=AluJb |
| ADediting_750585 | chr19_40276772_- | SINE | Alu | Name=AluJb |
| ADediting_750586 | chr19_40276781_- | SINE | Alu | Name=AluJb |
| ADediting_750587 | chr19_40276811_- | SINE | Alu | Name=AluJb |
| ADediting_750588 | chr19_40276818_- | SINE | Alu | Name=AluJb |
| ADediting_750589 | chr19_40276824_- | SINE | Alu | Name=AluJb |
| ADediting_750590 | chr19_40276849_- | SINE | Alu | Name=AluJb |
| ADediting_750591 | chr19_40276851_- | SINE | Alu | Name=AluJb |
| ADediting_750592 | chr19_40276854_- | SINE | Alu | Name=AluJb |
| ADediting_750593 | chr19_40276895_- | SINE | Alu | Name=AluJb |
| ADediting_750594 | chr19_40276899_- | SINE | Alu | Name=AluJb |
| ADediting_750595 | chr19_40276901_- | SINE | Alu | Name=AluJb |
| ADediting_750596 | chr19_40276904_- | SINE | Alu | Name=AluJb |
| ADediting_750597 | chr19_40276911_- | SINE | Alu | Name=AluJb |
| ADediting_750598 | chr19_40276923_- | SINE | Alu | Name=AluJb |
| ADediting_750599 | chr19_40276928_- | SINE | Alu | Name=AluJb |
| ADediting_750600 | chr19_40276954_- | SINE | Alu | Name=AluJb |
| ADediting_750601 | chr19_40276973_- | SINE | Alu | Name=AluJb |
| ADediting_750602 | chr19_40276979_- | SINE | Alu | Name=AluJb |
| ADediting_750603 | chr19_40276985_- | SINE | Alu | Name=AluJb |
| ADediting_750604 | chr19_40276989_- | SINE | Alu | Name=AluJb |
| ADediting_750605 | chr19_40276997_- | SINE | Alu | Name=AluJb |
| ADediting_750606 | chr19_40277001_- | SINE | Alu | Name=AluJb |
| ADediting_750607 | chr19_40277017_- | SINE | Alu | Name=AluJb |
| ADediting_750608 | chr19_40277021_- | SINE | Alu | Name=AluJb |
| ADediting_750610 | chr19_40281368_- | SINE | Alu | Name=AluJr |
| ADediting_750611 | chr19_40281370_- | SINE | Alu | Name=AluJr |
| ADediting_750612 | chr19_40281397_- | SINE | Alu | Name=AluJr |
| ADediting_750613 | chr19_40281423_- | SINE | Alu | Name=AluJr |
| ADediting_750617 | chr19_40282676_- | SINE | MIR | Name=MIR3 |
| ADediting_1556044 | chr19_40230987_- | SINE | Alu | Name=AluJr |
| ADediting_1556046 | chr19_40241061_- | SINE | Alu | Name=AluJo |
| ADediting_1556047 | chr19_40244332_- | SINE | Alu | Name=AluJr |
| ADediting_1556048 | chr19_40246329_- | SINE | Alu | Name=AluSc |
| ADediting_1556049 | chr19_40246366_- | SINE | Alu | Name=AluSc |
| ADediting_1556051 | chr19_40250716_- | SINE | Alu | Name=AluJb |
| ADediting_1556052 | chr19_40254802_- | SINE | Alu | Name=AluSq |
| ADediting_1556053 | chr19_40270840_- | SINE | Alu | Name=AluJr |
| ADediting_1556054 | chr19_40270961_- | SINE | Alu | Name=AluJr |
| ADediting_1556060 | chr19_40275742_- | SINE | Alu | Name=AluSg7 |
| ADediting_1556061 | chr19_40276537_- | SINE | Alu | Name=AluSg7 |
| ADediting_1556062 | chr19_40276561_- | SINE | Alu | Name=AluSg7 |
| ADediting_1556063 | chr19_40276888_- | SINE | Alu | Name=AluJb |
| ADediting_1556064 | chr19_40276891_- | SINE | Alu | Name=AluJb |
| ADediting_1556065 | chr19_40281294_- | SINE | Alu | Name=AluJr |
| ADediting_1631457 | chr19_40250341_- | SINE | Alu | Name=AluSp |
Top |
RNA A-to-I editing events in the alternative splicing sites for AKT2 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| A3SS | ADediting_750508 | chr19_40270778_- | 40270774:40270796 | 3ss | 2i | AAGAGATCCTCTTGCCTCAGCCT | 0.39 | AAGAGATCCTCTTGCCTCGGCCT | -7.57 |
| ES | ADediting_750508 | chr19_40270778_- | 40270774:40270796 | 3ss | 2i | AAGAGATCCTCTTGCCTCAGCCT | 0.39 | AAGAGATCCTCTTGCCTCGGCCT | -7.57 |
| ES | ADediting_750508 | chr19_40270778_- | 40270774:40270796 | 3ss | 2i | AAGAGATCCTCTTGCCTCAGCCT | 0.39 | AAGAGATCCTCTTGCCTCGGCCT | -7.57 |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for AKT2 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
 | |
| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
 |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for AKT2 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for AKT2 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_750419 | chr19_40230788_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-324-3p | chr19 | 40230788 | 40230794 | 7mer-m8 | 40230787 | 40230810 | 148 | -29.77 |
| ADediting_750419 | chr19_40230788_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-3651 | chr19 | 40230783 | 40230789 | 7mer-m8 | 40230782 | 40230804 | 151 | -20.62 |
| ADediting_750419 | chr19_40230788_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-324-3p | chr19 | 40230788 | 40230794 | 7mer-m8 | 40230787 | 40230810 | 148 | -29.77 |
| ADediting_750419 | chr19_40230788_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-3651 | chr19 | 40230783 | 40230789 | 7mer-m8 | 40230782 | 40230804 | 151 | -20.62 |
| ADediting_750421 | chr19_40230813_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-3136-3p | chr19 | 40230810 | 40230816 | 7mer-m8 | 40230809 | 40230830 | 142 | -14.96 |
| ADediting_750421 | chr19_40230813_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-6724-5p | chr19 | 40230808 | 40230814 | 7mer-m8 | 40230807 | 40230828 | 145 | -22.57 |
| ADediting_750421 | chr19_40230813_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-6773-5p | chr19 | 40230808 | 40230814 | 7mer-m8 | 40230807 | 40230829 | 153 | -23.04 |
| ADediting_750421 | chr19_40230813_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-7155-3p | chr19 | 40230810 | 40230816 | 7mer-m8 | 40230809 | 40230827 | 146 | -16.99 |
| ADediting_750421 | chr19_40230813_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-3136-3p | chr19 | 40230810 | 40230816 | 7mer-m8 | 40230809 | 40230830 | 142 | -14.96 |
| ADediting_750421 | chr19_40230813_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-6724-5p | chr19 | 40230808 | 40230814 | 7mer-m8 | 40230807 | 40230828 | 145 | -22.57 |
| ADediting_750421 | chr19_40230813_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-6773-5p | chr19 | 40230808 | 40230814 | 7mer-m8 | 40230807 | 40230829 | 153 | -23.04 |
| ADediting_750421 | chr19_40230813_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-7155-3p | chr19 | 40230810 | 40230816 | 7mer-m8 | 40230809 | 40230827 | 146 | -16.99 |
| ADediting_750423 | chr19_40230823_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-532-3p | chr19 | 40230823 | 40230829 | 7mer-m8 | 40230822 | 40230846 | 154 | -28.7 |
| ADediting_750423 | chr19_40230823_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-6749-3p | chr19 | 40230821 | 40230827 | 7mer-m8 | 40230820 | 40230844 | 151 | -28.01 |
| ADediting_750423 | chr19_40230823_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-532-3p | chr19 | 40230823 | 40230829 | 7mer-m8 | 40230822 | 40230846 | 154 | -28.7 |
| ADediting_750423 | chr19_40230823_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-6749-3p | chr19 | 40230821 | 40230827 | 7mer-m8 | 40230820 | 40230844 | 151 | -28.01 |
| ADediting_750424 | chr19_40230842_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-4290 | chr19 | 40230839 | 40230845 | 7mer-m8 | 40230838 | 40230856 | 140 | -14.16 |
| ADediting_750424 | chr19_40230842_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-4687-5p | chr19 | 40230838 | 40230844 | 7mer-m8 | 40230837 | 40230858 | 145 | -20.92 |
| ADediting_750424 | chr19_40230842_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-5695 | chr19 | 40230842 | 40230848 | 7mer-m8 | 40230841 | 40230862 | 140 | -11.91 |
| ADediting_750424 | chr19_40230842_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-4290 | chr19 | 40230839 | 40230845 | 7mer-m8 | 40230838 | 40230856 | 140 | -14.16 |
| ADediting_750424 | chr19_40230842_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-4687-5p | chr19 | 40230838 | 40230844 | 7mer-m8 | 40230837 | 40230858 | 145 | -20.92 |
| ADediting_750424 | chr19_40230842_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-5695 | chr19 | 40230842 | 40230848 | 7mer-m8 | 40230841 | 40230862 | 140 | -11.91 |
| ADediting_750425 | chr19_40230859_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-10394-5p | chr19 | 40230859 | 40230865 | 7mer-m8 | 40230858 | 40230878 | 145 | -23.96 |
| ADediting_750425 | chr19_40230859_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-1205 | chr19 | 40230859 | 40230865 | 7mer-m8 | 40230858 | 40230876 | 144 | -15.8 |
| ADediting_750425 | chr19_40230859_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-1288-3p | chr19 | 40230856 | 40230862 | 7mer-m8 | 40230855 | 40230875 | 140 | -12.22 |
| ADediting_750425 | chr19_40230859_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-3199 | chr19 | 40230854 | 40230861 | 8mer-1a | 40230854 | 40230876 | 145 | -18.74 |
| ADediting_750425 | chr19_40230859_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-4418 | chr19 | 40230858 | 40230864 | 7mer-m8 | 40230857 | 40230875 | 147 | -17.67 |
| ADediting_750425 | chr19_40230859_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-509-3-5p | chr19 | 40230858 | 40230864 | 7mer-m8 | 40230857 | 40230879 | 163 | -23.59 |
| ADediting_750425 | chr19_40230859_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-509-5p | chr19 | 40230858 | 40230864 | 7mer-m8 | 40230857 | 40230878 | 152 | -17.65 |
| ADediting_750425 | chr19_40230859_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-8052 | chr19 | 40230854 | 40230861 | 8mer-1a | 40230854 | 40230872 | 159 | -25.45 |
| ADediting_750425 | chr19_40230859_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-10394-5p | chr19 | 40230859 | 40230865 | 7mer-m8 | 40230858 | 40230878 | 145 | -23.96 |
| ADediting_750425 | chr19_40230859_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-1205 | chr19 | 40230859 | 40230865 | 7mer-m8 | 40230858 | 40230876 | 144 | -15.8 |
| ADediting_750425 | chr19_40230859_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-1288-3p | chr19 | 40230856 | 40230862 | 7mer-m8 | 40230855 | 40230875 | 140 | -12.22 |
| ADediting_750425 | chr19_40230859_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-3199 | chr19 | 40230854 | 40230861 | 8mer-1a | 40230854 | 40230876 | 145 | -18.74 |
| ADediting_750425 | chr19_40230859_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-4418 | chr19 | 40230858 | 40230864 | 7mer-m8 | 40230857 | 40230875 | 147 | -17.67 |
| ADediting_750425 | chr19_40230859_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-509-3-5p | chr19 | 40230858 | 40230864 | 7mer-m8 | 40230857 | 40230879 | 163 | -23.59 |
| ADediting_750425 | chr19_40230859_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-509-5p | chr19 | 40230858 | 40230864 | 7mer-m8 | 40230857 | 40230878 | 152 | -17.65 |
| ADediting_750425 | chr19_40230859_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-8052 | chr19 | 40230854 | 40230861 | 8mer-1a | 40230854 | 40230872 | 159 | -25.45 |
| ADediting_750426 | chr19_40230860_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-638 | chr19 | 40230854 | 40230861 | 8mer-1a | 40230854 | 40230878 | 171 | -33.9 |
| ADediting_750426 | chr19_40230860_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-638 | chr19 | 40230854 | 40230861 | 8mer-1a | 40230854 | 40230878 | 171 | -33.9 |
| ADediting_750430 | chr19_40230890_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-6844 | chr19 | 40230889 | 40230895 | 7mer-m8 | 40230888 | 40230908 | 152 | -7.49 |
| ADediting_750430 | chr19_40230890_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-6844 | chr19 | 40230889 | 40230895 | 7mer-m8 | 40230888 | 40230908 | 152 | -7.49 |
| ADediting_750431 | chr19_40230891_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-578 | chr19 | 40230889 | 40230895 | 7mer-m8 | 40230888 | 40230908 | 145 | -7.69 |
| ADediting_750431 | chr19_40230891_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-643 | chr19 | 40230890 | 40230897 | 8mer-1a | 40230890 | 40230911 | 140 | -10.49 |
| ADediting_750431 | chr19_40230891_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-578 | chr19 | 40230889 | 40230895 | 7mer-m8 | 40230888 | 40230908 | 145 | -7.69 |
| ADediting_750431 | chr19_40230891_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-643 | chr19 | 40230890 | 40230897 | 8mer-1a | 40230890 | 40230911 | 140 | -10.49 |
| ADediting_750432 | chr19_40230895_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-153-5p | chr19 | 40230895 | 40230901 | 7mer-m8 | 40230894 | 40230916 | 155 | -9.35 |
| ADediting_750432 | chr19_40230895_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-3680-3p | chr19 | 40230890 | 40230897 | 8mer-1a | 40230890 | 40230912 | 140 | -13.11 |
| ADediting_750432 | chr19_40230895_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-153-5p | chr19 | 40230895 | 40230901 | 7mer-m8 | 40230894 | 40230916 | 155 | -9.35 |
| ADediting_750432 | chr19_40230895_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-3680-3p | chr19 | 40230890 | 40230897 | 8mer-1a | 40230890 | 40230912 | 140 | -13.11 |
| ADediting_750434 | chr19_40230899_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-630 | chr19 | 40230893 | 40230900 | 8mer-1a | 40230893 | 40230916 | 152 | -16.93 |
| ADediting_750434 | chr19_40230899_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-6844 | chr19 | 40230897 | 40230904 | 8mer-1a | 40230897 | 40230917 | 140 | -8.12 |
| ADediting_750434 | chr19_40230899_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-630 | chr19 | 40230893 | 40230900 | 8mer-1a | 40230893 | 40230916 | 152 | -16.93 |
| ADediting_750434 | chr19_40230899_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-6844 | chr19 | 40230897 | 40230904 | 8mer-1a | 40230897 | 40230917 | 140 | -8.12 |
| ADediting_750437 | chr19_40230904_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-3678-3p | chr19 | 40230901 | 40230908 | 8mer-1a | 40230901 | 40230920 | 143 | -13.95 |
| ADediting_750437 | chr19_40230904_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-3678-3p | chr19 | 40230901 | 40230908 | 8mer-1a | 40230901 | 40230920 | 143 | -13.95 |
| ADediting_750440 | chr19_40230986_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-3692-5p | chr19 | 40230986 | 40230992 | 7mer-m8 | 40230985 | 40231013 | 151 | -27.45 |
| ADediting_750440 | chr19_40230986_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-548av-3p | chr19 | 40230983 | 40230989 | 7mer-m8 | 40230982 | 40231004 | 145 | -9.46 |
| ADediting_750440 | chr19_40230986_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-3692-5p | chr19 | 40230986 | 40230992 | 7mer-m8 | 40230985 | 40231013 | 151 | -27.45 |
| ADediting_750440 | chr19_40230986_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-548av-3p | chr19 | 40230983 | 40230989 | 7mer-m8 | 40230982 | 40231004 | 145 | -9.46 |
| ADediting_750442 | chr19_40230995_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-8052 | chr19 | 40230990 | 40230996 | 7mer-1a | 40230990 | 40231008 | 148 | -29.06 |
| ADediting_750442 | chr19_40230995_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-8052 | chr19 | 40230990 | 40230996 | 7mer-1a | 40230990 | 40231008 | 148 | -29.06 |
| ADediting_750443 | chr19_40230996_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-513a-5p | chr19 | 40230995 | 40231001 | 7mer-m8 | 40230994 | 40231011 | 152 | -17.32 |
| ADediting_750443 | chr19_40230996_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-638 | chr19 | 40230990 | 40230996 | 7mer-1a | 40230990 | 40231014 | 153 | -31.53 |
| ADediting_750443 | chr19_40230996_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-513a-5p | chr19 | 40230995 | 40231001 | 7mer-m8 | 40230994 | 40231011 | 152 | -17.32 |
| ADediting_750443 | chr19_40230996_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-638 | chr19 | 40230990 | 40230996 | 7mer-1a | 40230990 | 40231014 | 153 | -31.53 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1556044 | chr19_40230987_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-302f | chr19 | 40230984 | 40230990 | 7mer-m8 | 40230983 | 40230999 | 141 | -6.19 |
| ADediting_1556044 | chr19_40230987_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-302f | chr19 | 40230984 | 40230990 | 7mer-m8 | 40230983 | 40230999 | 141 | -6.19 |
| ADediting_750419 | chr19_40230788_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-7705 | chr19 | 40230783 | 40230789 | 7mer-m8 | 40230782 | 40230801 | 147 | -16.49 |
| ADediting_750419 | chr19_40230788_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-7705 | chr19 | 40230783 | 40230789 | 7mer-m8 | 40230782 | 40230801 | 147 | -16.49 |
| ADediting_750420 | chr19_40230808_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-10400-3p | chr19 | 40230808 | 40230814 | 7mer-m8 | 40230807 | 40230828 | 140 | -20.64 |
| ADediting_750420 | chr19_40230808_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-1343-3p | chr19 | 40230805 | 40230811 | 7mer-m8 | 40230804 | 40230825 | 140 | -19.96 |
| ADediting_750420 | chr19_40230808_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-4674 | chr19 | 40230808 | 40230814 | 7mer-m8 | 40230807 | 40230827 | 147 | -22.8 |
| ADediting_750420 | chr19_40230808_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-6783-3p | chr19 | 40230805 | 40230811 | 7mer-m8 | 40230804 | 40230825 | 151 | -20.85 |
| ADediting_750420 | chr19_40230808_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-939-3p | chr19 | 40230805 | 40230812 | 8mer-1a | 40230805 | 40230829 | 143 | -23.21 |
| ADediting_750420 | chr19_40230808_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-10400-3p | chr19 | 40230808 | 40230814 | 7mer-m8 | 40230807 | 40230828 | 140 | -20.64 |
| ADediting_750420 | chr19_40230808_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-1343-3p | chr19 | 40230805 | 40230811 | 7mer-m8 | 40230804 | 40230825 | 140 | -19.96 |
| ADediting_750420 | chr19_40230808_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-4674 | chr19 | 40230808 | 40230814 | 7mer-m8 | 40230807 | 40230827 | 147 | -22.8 |
| ADediting_750420 | chr19_40230808_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-6783-3p | chr19 | 40230805 | 40230811 | 7mer-m8 | 40230804 | 40230825 | 151 | -20.85 |
| ADediting_750420 | chr19_40230808_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-939-3p | chr19 | 40230805 | 40230812 | 8mer-1a | 40230805 | 40230829 | 143 | -23.21 |
| ADediting_750421 | chr19_40230813_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-10400-3p | chr19 | 40230808 | 40230814 | 7mer-m8 | 40230807 | 40230828 | 140 | -20.64 |
| ADediting_750421 | chr19_40230813_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-4437 | chr19 | 40230808 | 40230815 | 8mer-1a | 40230808 | 40230828 | 146 | -19.6 |
| ADediting_750421 | chr19_40230813_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-4674 | chr19 | 40230808 | 40230814 | 7mer-m8 | 40230807 | 40230827 | 147 | -22.8 |
| ADediting_750421 | chr19_40230813_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-10400-3p | chr19 | 40230808 | 40230814 | 7mer-m8 | 40230807 | 40230828 | 140 | -20.64 |
| ADediting_750421 | chr19_40230813_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-4437 | chr19 | 40230808 | 40230815 | 8mer-1a | 40230808 | 40230828 | 146 | -19.6 |
| ADediting_750421 | chr19_40230813_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-4674 | chr19 | 40230808 | 40230814 | 7mer-m8 | 40230807 | 40230827 | 147 | -22.8 |
| ADediting_750422 | chr19_40230818_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-1245a | chr19 | 40230816 | 40230822 | 7mer-m8 | 40230815 | 40230836 | 150 | -19.33 |
| ADediting_750422 | chr19_40230818_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-1245a | chr19 | 40230816 | 40230822 | 7mer-m8 | 40230815 | 40230836 | 150 | -19.33 |
| ADediting_750423 | chr19_40230823_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-141-5p | chr19 | 40230820 | 40230826 | 7mer-m8 | 40230819 | 40230841 | 141 | -12.17 |
| ADediting_750423 | chr19_40230823_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-141-5p | chr19 | 40230820 | 40230826 | 7mer-m8 | 40230819 | 40230841 | 141 | -12.17 |
| ADediting_750424 | chr19_40230842_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-3614-3p | chr19 | 40230838 | 40230844 | 7mer-m8 | 40230837 | 40230859 | 151 | -16.08 |
| ADediting_750424 | chr19_40230842_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-4297 | chr19 | 40230839 | 40230845 | 7mer-m8 | 40230838 | 40230853 | 140 | -13.4 |
| ADediting_750424 | chr19_40230842_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-3614-3p | chr19 | 40230838 | 40230844 | 7mer-m8 | 40230837 | 40230859 | 151 | -16.08 |
| ADediting_750424 | chr19_40230842_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-4297 | chr19 | 40230839 | 40230845 | 7mer-m8 | 40230838 | 40230853 | 140 | -13.4 |
| ADediting_750425 | chr19_40230859_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-5089-5p | chr19 | 40230854 | 40230860 | 7mer-m8 | 40230853 | 40230873 | 152 | -18.63 |
| ADediting_750425 | chr19_40230859_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-5089-5p | chr19 | 40230854 | 40230860 | 7mer-m8 | 40230853 | 40230873 | 152 | -18.63 |
| ADediting_750426 | chr19_40230860_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-6511b-5p | chr19 | 40230859 | 40230866 | 8mer-1a | 40230859 | 40230882 | 145 | -16.55 |
| ADediting_750426 | chr19_40230860_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-6511b-5p | chr19 | 40230859 | 40230866 | 8mer-1a | 40230859 | 40230882 | 145 | -16.55 |
| ADediting_750428 | chr19_40230878_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-6872-3p | chr19 | 40230875 | 40230881 | 7mer-m8 | 40230874 | 40230894 | 141 | -13.85 |
| ADediting_750428 | chr19_40230878_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-6872-3p | chr19 | 40230875 | 40230881 | 7mer-m8 | 40230874 | 40230894 | 141 | -13.85 |
| ADediting_750429 | chr19_40230886_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-4735-5p | chr19 | 40230885 | 40230891 | 7mer-m8 | 40230884 | 40230905 | 140 | -4.7 |
| ADediting_750429 | chr19_40230886_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-4735-5p | chr19 | 40230885 | 40230891 | 7mer-m8 | 40230884 | 40230905 | 140 | -4.7 |
| ADediting_750430 | chr19_40230890_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-4735-5p | chr19 | 40230885 | 40230891 | 7mer-m8 | 40230884 | 40230905 | 140 | -4.7 |
| ADediting_750430 | chr19_40230890_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-4735-5p | chr19 | 40230885 | 40230891 | 7mer-m8 | 40230884 | 40230905 | 140 | -4.7 |
| ADediting_750435 | chr19_40230901_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-3674 | chr19 | 40230900 | 40230907 | 8mer-1a | 40230900 | 40230921 | 146 | -10.13 |
| ADediting_750435 | chr19_40230901_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-3674 | chr19 | 40230900 | 40230907 | 8mer-1a | 40230900 | 40230921 | 146 | -10.13 |
| ADediting_750436 | chr19_40230902_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-3674 | chr19 | 40230900 | 40230907 | 8mer-1a | 40230900 | 40230921 | 146 | -10.13 |
| ADediting_750436 | chr19_40230902_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-3674 | chr19 | 40230900 | 40230907 | 8mer-1a | 40230900 | 40230921 | 146 | -10.13 |
| ADediting_750437 | chr19_40230904_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-3674 | chr19 | 40230900 | 40230907 | 8mer-1a | 40230900 | 40230921 | 146 | -10.13 |
| ADediting_750437 | chr19_40230904_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-6832-5p | chr19 | 40230902 | 40230909 | 8mer-1a | 40230902 | 40230924 | 152 | -15.27 |
| ADediting_750437 | chr19_40230904_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-3674 | chr19 | 40230900 | 40230907 | 8mer-1a | 40230900 | 40230921 | 146 | -10.13 |
| ADediting_750437 | chr19_40230904_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-6832-5p | chr19 | 40230902 | 40230909 | 8mer-1a | 40230902 | 40230924 | 152 | -15.27 |
| ADediting_750438 | chr19_40230918_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-4685-3p | chr19 | 40230916 | 40230922 | 7mer-1a | 40230916 | 40230938 | 140 | -30.48 |
| ADediting_750438 | chr19_40230918_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-6867-3p | chr19 | 40230916 | 40230922 | 7mer-m8 | 40230915 | 40230936 | 152 | -16.68 |
| ADediting_750438 | chr19_40230918_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-6883-3p | chr19 | 40230918 | 40230924 | 7mer-m8 | 40230917 | 40230942 | 143 | -16.46 |
| ADediting_750438 | chr19_40230918_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-4685-3p | chr19 | 40230916 | 40230922 | 7mer-1a | 40230916 | 40230938 | 140 | -30.48 |
| ADediting_750438 | chr19_40230918_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-6867-3p | chr19 | 40230916 | 40230922 | 7mer-m8 | 40230915 | 40230936 | 152 | -16.68 |
| ADediting_750438 | chr19_40230918_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-6883-3p | chr19 | 40230918 | 40230924 | 7mer-m8 | 40230917 | 40230942 | 143 | -16.46 |
| ADediting_750439 | chr19_40230922_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-4685-3p | chr19 | 40230916 | 40230922 | 7mer-1a | 40230916 | 40230938 | 140 | -30.48 |
| ADediting_750439 | chr19_40230922_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-6883-3p | chr19 | 40230918 | 40230924 | 7mer-m8 | 40230917 | 40230942 | 143 | -16.46 |
| ADediting_750439 | chr19_40230922_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-4685-3p | chr19 | 40230916 | 40230922 | 7mer-1a | 40230916 | 40230938 | 140 | -30.48 |
| ADediting_750439 | chr19_40230922_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-6883-3p | chr19 | 40230918 | 40230924 | 7mer-m8 | 40230917 | 40230942 | 143 | -16.46 |
| ADediting_750440 | chr19_40230986_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-302f | chr19 | 40230984 | 40230990 | 7mer-m8 | 40230983 | 40230999 | 141 | -6.19 |
| ADediting_750440 | chr19_40230986_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-302f | chr19 | 40230984 | 40230990 | 7mer-m8 | 40230983 | 40230999 | 141 | -6.19 |
| ADediting_750441 | chr19_40230990_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-5089-5p | chr19 | 40230990 | 40230996 | 7mer-m8 | 40230989 | 40231008 | 146 | -13.24 |
| ADediting_750441 | chr19_40230990_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-6506-5p | chr19 | 40230989 | 40230995 | 7mer-m8 | 40230988 | 40231010 | 144 | -16.21 |
| ADediting_750441 | chr19_40230990_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-5089-5p | chr19 | 40230990 | 40230996 | 7mer-m8 | 40230989 | 40231008 | 146 | -13.24 |
| ADediting_750441 | chr19_40230990_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-6506-5p | chr19 | 40230989 | 40230995 | 7mer-m8 | 40230988 | 40231010 | 144 | -16.21 |
| ADediting_750442 | chr19_40230995_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-10399-5p | chr19 | 40230994 | 40231000 | 7mer-m8 | 40230993 | 40231014 | 144 | -10.53 |
| ADediting_750442 | chr19_40230995_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-5089-5p | chr19 | 40230990 | 40230996 | 7mer-m8 | 40230989 | 40231008 | 146 | -13.24 |
| ADediting_750442 | chr19_40230995_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-10399-5p | chr19 | 40230994 | 40231000 | 7mer-m8 | 40230993 | 40231014 | 144 | -10.53 |
| ADediting_750442 | chr19_40230995_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-5089-5p | chr19 | 40230990 | 40230996 | 7mer-m8 | 40230989 | 40231008 | 146 | -13.24 |
| ADediting_750443 | chr19_40230996_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-10399-5p | chr19 | 40230994 | 40231000 | 7mer-m8 | 40230993 | 40231014 | 144 | -10.53 |
| ADediting_750443 | chr19_40230996_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-7151-3p | chr19 | 40230995 | 40231002 | 8mer-1a | 40230995 | 40231011 | 146 | -17.62 |
| ADediting_750443 | chr19_40230996_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-10399-5p | chr19 | 40230994 | 40231000 | 7mer-m8 | 40230993 | 40231014 | 144 | -10.53 |
| ADediting_750443 | chr19_40230996_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-7151-3p | chr19 | 40230995 | 40231002 | 8mer-1a | 40230995 | 40231011 | 146 | -17.62 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_750503 | chr19_40268954_- | ENSG00000105221.18 | ENST00000498350.1 | AKT2-227 | hsa-miR-4421 | chr19 | 40268952 | 40268959 | 8mer-1a | 40268952 | 40268975 | 154 | -20.07 |
| ADediting_750503 | chr19_40268954_- | ENSG00000105221.18 | ENST00000498350.1 | AKT2-227 | hsa-miR-5699-3p | chr19 | 40268952 | 40268959 | 8mer-1a | 40268952 | 40268973 | 149 | -19.76 |
| ADediting_750504 | chr19_40269044_- | ENSG00000105221.18 | ENST00000498350.1 | AKT2-227 | hsa-miR-25-5p | chr19 | 40269042 | 40269048 | 7mer-m8 | 40269041 | 40269062 | 148 | -21.05 |
| ADediting_750504 | chr19_40269044_- | ENSG00000105221.18 | ENST00000498350.1 | AKT2-227 | hsa-miR-658 | chr19 | 40269043 | 40269049 | 7mer-m8 | 40269042 | 40269067 | 143 | -27.38 |
| ADediting_750505 | chr19_40269053_- | ENSG00000105221.18 | ENST00000498350.1 | AKT2-227 | hsa-miR-5739 | chr19 | 40269053 | 40269059 | 7mer-m8 | 40269052 | 40269071 | 144 | -21.24 |
| ADediting_750505 | chr19_40269053_- | ENSG00000105221.18 | ENST00000498350.1 | AKT2-227 | hsa-miR-658 | chr19 | 40269051 | 40269057 | 7mer-1a | 40269051 | 40269078 | 149 | -28.4 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_750504 | chr19_40269044_- | ENSG00000105221.18 | ENST00000498350.1 | AKT2-227 | hsa-miR-3689d | chr19 | 40269039 | 40269045 | 7mer-m8 | 40269038 | 40269058 | 141 | -17.7 |
| ADediting_750504 | chr19_40269044_- | ENSG00000105221.18 | ENST00000498350.1 | AKT2-227 | hsa-miR-6851-5p | chr19 | 40269039 | 40269045 | 7mer-m8 | 40269038 | 40269064 | 151 | -26.73 |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-5688 | chr19 | 40231436 | 40231442 | 7mer-m8 | 40231435 | 40231453 | 151 | -11.1 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-5688 | chr19 | 40231436 | 40231442 | 7mer-m8 | 40231435 | 40231453 | 151 | -11.1 |
| ADediting_496066 | chr15_66496985_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-4512 | chr19 | 40231873 | 40231879 | 7mer-m8 | 40231872 | 40231893 | 157 | -21.42 |
| ADediting_496066 | chr15_66496985_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-4512 | chr19 | 40232876 | 40232882 | 7mer-m8 | 40232875 | 40232896 | 143 | -20.89 |
| ADediting_496066 | chr15_66496985_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-4512 | chr19 | 40233429 | 40233435 | 7mer-m8 | 40233428 | 40233450 | 151 | -26.18 |
| ADediting_496066 | chr15_66496985_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-4512 | chr19 | 40233732 | 40233738 | 7mer-m8 | 40233731 | 40233752 | 142 | -15.17 |
| ADediting_496066 | chr15_66496985_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-4512 | chr19 | 40231873 | 40231879 | 7mer-m8 | 40231872 | 40231893 | 157 | -21.42 |
| ADediting_496066 | chr15_66496985_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-4512 | chr19 | 40232876 | 40232882 | 7mer-m8 | 40232875 | 40232896 | 143 | -20.89 |
| ADediting_496066 | chr15_66496985_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-4512 | chr19 | 40233429 | 40233435 | 7mer-m8 | 40233428 | 40233450 | 151 | -26.18 |
| ADediting_496066 | chr15_66496985_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-4512 | chr19 | 40233732 | 40233738 | 7mer-m8 | 40233731 | 40233752 | 142 | -15.17 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1643790 | chr3_121049689_+ | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-5682 | chr19 | 40230353 | 40230359 | 7mer-m8 | 40230352 | 40230374 | 151 | -21.5 |
| ADediting_1643790 | chr3_121049689_+ | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-5682 | chr19 | 40230353 | 40230359 | 7mer-m8 | 40230352 | 40230374 | 151 | -21.5 |
| ADediting_291761 | chr11_93733708_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-1304-3p | chr19 | 40233575 | 40233581 | 7mer-m8 | 40233574 | 40233595 | 146 | -14.97 |
| ADediting_291761 | chr11_93733708_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-1304-3p | chr19 | 40233575 | 40233581 | 7mer-m8 | 40233574 | 40233595 | 146 | -14.97 |
| ADediting_496066 | chr15_66496985_- | ENSG00000105221.18 | ENST00000392038.7 | AKT2-206 | hsa-miR-4512 | chr19 | 40232073 | 40232079 | 7mer-m8 | 40232072 | 40232095 | 143 | -16.08 |
| ADediting_496066 | chr15_66496985_- | ENSG00000105221.18 | ENST00000424901.5 | AKT2-210 | hsa-miR-4512 | chr19 | 40232073 | 40232079 | 7mer-m8 | 40232072 | 40232095 | 143 | -16.08 |
| Differentially expressed gene-miRNA network |
Top |
The effects of the RNA editing to the stability of the RNA structures for AKT2 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000392038.7 | protein_coding |  |  |
| ENST00000424901.5 | protein_coding |  |  |
| ENST00000416362.5 | protein_coding |  |  |
| ENST00000498350.1 | lncRNA |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_750419 | ENST00000392038.7 | chr19_40230788_- | 4779 | -2232.20 | -2231.70 | -2258.60 |
| ADediting_750420 | ENST00000392038.7 | chr19_40230808_- | 4759 | -2233.10 | -2231.70 | -2258.60 |
| ADediting_750421 | ENST00000392038.7 | chr19_40230813_- | 4754 | -2232.90 | -2231.70 | -2258.60 |
| ADediting_750422 | ENST00000392038.7 | chr19_40230818_- | 4749 | -2231.30 | -2231.70 | -2258.60 |
| ADediting_750423 | ENST00000392038.7 | chr19_40230823_- | 4744 | -2232.20 | -2231.70 | -2258.60 |
| ADediting_750424 | ENST00000392038.7 | chr19_40230842_- | 4725 | -2233.70 | -2231.70 | -2258.60 |
| ADediting_750425 | ENST00000392038.7 | chr19_40230859_- | 4708 | -2232.30 | -2231.70 | -2258.60 |
| ADediting_750426 | ENST00000392038.7 | chr19_40230860_- | 4707 | -2233.40 | -2231.70 | -2258.60 |
| ADediting_750428 | ENST00000392038.7 | chr19_40230878_- | 4689 | -2231.60 | -2231.70 | -2258.60 |
| ADediting_750429 | ENST00000392038.7 | chr19_40230886_- | 4681 | -2231.40 | -2231.70 | -2258.60 |
| ADediting_750430 | ENST00000392038.7 | chr19_40230890_- | 4677 | -2233.60 | -2231.70 | -2258.60 |
| ADediting_750431 | ENST00000392038.7 | chr19_40230891_- | 4676 | -2232.90 | -2231.70 | -2258.60 |
| ADediting_750432 | ENST00000392038.7 | chr19_40230895_- | 4672 | -2231.70 | -2231.70 | -2258.60 |
| ADediting_750433 | ENST00000392038.7 | chr19_40230898_- | 4669 | -2232.70 | -2231.70 | -2258.60 |
| ADediting_750434 | ENST00000392038.7 | chr19_40230899_- | 4668 | -2232.50 | -2231.70 | -2258.60 |
| ADediting_750435 | ENST00000392038.7 | chr19_40230901_- | 4666 | -2231.90 | -2231.70 | -2258.60 |
| ADediting_750436 | ENST00000392038.7 | chr19_40230902_- | 4665 | -2232.30 | -2231.70 | -2258.60 |
| ADediting_750437 | ENST00000392038.7 | chr19_40230904_- | 4663 | -2236.50 | -2231.70 | -2258.60 |
| ADediting_750438 | ENST00000392038.7 | chr19_40230918_- | 4649 | -2231.90 | -2231.70 | -2258.60 |
| ADediting_750439 | ENST00000392038.7 | chr19_40230922_- | 4645 | -2231.70 | -2231.70 | -2258.60 |
| ADediting_750440 | ENST00000392038.7 | chr19_40230986_- | 4581 | -2233.50 | -2231.70 | -2258.60 |
| ADediting_1556044 | ENST00000392038.7 | chr19_40230987_- | 4580 | -2231.70 | -2231.70 | -2258.60 |
| ADediting_750441 | ENST00000392038.7 | chr19_40230990_- | 4577 | -2230.90 | -2231.70 | -2258.60 |
| ADediting_750442 | ENST00000392038.7 | chr19_40230995_- | 4572 | -2232.70 | -2231.70 | -2258.60 |
| ADediting_750443 | ENST00000392038.7 | chr19_40230996_- | 4571 | -2232.00 | -2231.70 | -2258.60 |
| ADediting_750419 | ENST00000424901.5 | chr19_40230788_- | 4700 | -2223.60 | -2223.10 | -2242.80 |
| ADediting_750420 | ENST00000424901.5 | chr19_40230808_- | 4680 | -2224.50 | -2223.10 | -2242.80 |
| ADediting_750421 | ENST00000424901.5 | chr19_40230813_- | 4675 | -2225.10 | -2223.10 | -2242.80 |
| ADediting_750422 | ENST00000424901.5 | chr19_40230818_- | 4670 | -2223.60 | -2223.10 | -2242.80 |
| ADediting_750423 | ENST00000424901.5 | chr19_40230823_- | 4665 | -2226.10 | -2223.10 | -2242.80 |
| ADediting_750424 | ENST00000424901.5 | chr19_40230842_- | 4646 | -2223.40 | -2223.10 | -2242.80 |
| ADediting_750425 | ENST00000424901.5 | chr19_40230859_- | 4629 | -2223.70 | -2223.10 | -2242.80 |
| ADediting_750426 | ENST00000424901.5 | chr19_40230860_- | 4628 | -2224.80 | -2223.10 | -2242.80 |
| ADediting_750428 | ENST00000424901.5 | chr19_40230878_- | 4610 | -2223.00 | -2223.10 | -2242.80 |
| ADediting_750429 | ENST00000424901.5 | chr19_40230886_- | 4602 | -2222.80 | -2223.10 | -2242.80 |
| ADediting_750430 | ENST00000424901.5 | chr19_40230890_- | 4598 | -2223.10 | -2223.10 | -2242.80 |
| ADediting_750431 | ENST00000424901.5 | chr19_40230891_- | 4597 | -2223.10 | -2223.10 | -2242.80 |
| ADediting_750432 | ENST00000424901.5 | chr19_40230895_- | 4593 | -2223.10 | -2223.10 | -2242.80 |
| ADediting_750433 | ENST00000424901.5 | chr19_40230898_- | 4590 | -2224.10 | -2223.10 | -2242.80 |
| ADediting_750434 | ENST00000424901.5 | chr19_40230899_- | 4589 | -2223.90 | -2223.10 | -2242.80 |
| ADediting_750435 | ENST00000424901.5 | chr19_40230901_- | 4587 | -2224.10 | -2223.10 | -2242.80 |
| ADediting_750436 | ENST00000424901.5 | chr19_40230902_- | 4586 | -2223.20 | -2223.10 | -2242.80 |
| ADediting_750437 | ENST00000424901.5 | chr19_40230904_- | 4584 | -2224.30 | -2223.10 | -2242.80 |
| ADediting_750438 | ENST00000424901.5 | chr19_40230918_- | 4570 | -2222.20 | -2223.10 | -2242.80 |
| ADediting_750439 | ENST00000424901.5 | chr19_40230922_- | 4566 | -2223.10 | -2223.10 | -2242.80 |
| ADediting_750440 | ENST00000424901.5 | chr19_40230986_- | 4502 | -2223.60 | -2223.10 | -2242.80 |
| ADediting_1556044 | ENST00000424901.5 | chr19_40230987_- | 4501 | -2222.80 | -2223.10 | -2242.80 |
| ADediting_750441 | ENST00000424901.5 | chr19_40230990_- | 4498 | -2222.60 | -2223.10 | -2242.80 |
| ADediting_750442 | ENST00000424901.5 | chr19_40230995_- | 4493 | -2223.80 | -2223.10 | -2242.80 |
| ADediting_750443 | ENST00000424901.5 | chr19_40230996_- | 4492 | -2226.20 | -2223.10 | -2242.80 |
| ADediting_750507 | ENST00000416362.5 | chr19_40270594_- | 176 | -353.70 | -351.40 | -353.70 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_750502 | ENST00000498350.1 | chr19_40268870_- | 334 | -212.10 | -212.10 | -213.70 |
| ADediting_750503 | ENST00000498350.1 | chr19_40268954_- | 250 | -212.50 | -212.10 | -213.70 |
| ADediting_750504 | ENST00000498350.1 | chr19_40269044_- | 160 | -213.30 | -212.10 | -213.70 |
| ADediting_750505 | ENST00000498350.1 | chr19_40269053_- | 151 | -212.10 | -212.10 | -213.70 |
Top |
Relation with ADAR for AKT2 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_750419 | chr19_40230788_- | 0.000341948158260904 | 0.288576279531934 | 5.01663966050933e-06 | 0.362907524504706 | 0.000148660083375363 | 0.304865555572169 |
| CER | ADediting_750420 | chr19_40230808_- | 1.04696149243429e-05 | 0.351253907582445 | 2.04035666118541e-13 | 0.553514323017187 | 2.42431679094877e-05 | 0.337364403699494 |
| CER | ADediting_750422 | chr19_40230818_- | 0.00244405766849901 | 0.245665495881696 | 2.53817985790204e-06 | 0.373306965732707 | 0.266261690699871 | 0.0913451942725363 |
| CER | ADediting_750423 | chr19_40230823_- | 0.00103578032467419 | 0.265265520258616 | 5.45113772474588e-11 | 0.502890897193093 | 6.68505488262484e-05 | 0.319646570062765 |
| CER | ADediting_750425 | chr19_40230859_- | 0.000466284064890045 | 0.282254804445592 | 6.64691155311524e-09 | 0.451544682928872 | 0.00025986227890287 | 0.294051527822956 |
| CER | ADediting_750426 | chr19_40230860_- | 0.014796564854616 | 0.198680322441909 | 1.85169936200517e-06 | 0.37800084552219 | 0.00135478637502868 | 0.259294631321052 |
| CER | ADediting_750428 | chr19_40230878_- | 0.00225278753624424 | 0.247591915809978 | 4.20009330597776e-10 | 0.482093230527854 | 0.000136414191035367 | 0.306493333604664 |
| CER | ADediting_750429 | chr19_40230886_- | 0.0787179804377722 | 0.144009723010303 | 4.09890709833417e-06 | 0.366029350335874 | 0.00685306195448728 | 0.219903051479149 |
| CER | ADediting_750430 | chr19_40230890_- | 0.0161518484548147 | 0.196134662585936 | 7.43235989921219e-07 | 0.391191061674314 | 0.000511302169929502 | 0.280347310072951 |
| CER | ADediting_750431 | chr19_40230891_- | 0.0688349598550505 | 0.148977768638421 | 4.64817756426286e-05 | 0.326120677774216 | 0.0139720020661565 | 0.200330475958736 |
| CER | ADediting_750432 | chr19_40230895_- | 0.0067325941433744 | 0.22037009672743 | 1.97954867384017e-07 | 0.409346370967409 | 0.000966729966760413 | 0.266777986757546 |
| CER | ADediting_750437 | chr19_40230904_- | 0.000919088821911638 | 0.267880368175923 | 1.7538101269945e-05 | 0.342798428783839 | 0.158996761398389 | 0.115580862803005 |
| CER | ADediting_750439 | chr19_40230922_- | 0.000182091692164948 | 0.300986488672609 | 6.03876581423946e-09 | 0.452658027903233 | 0.00241232256199962 | 0.245975448725744 |
| CER | ADediting_750442 | chr19_40230995_- | 0.00893178299983378 | 0.212814618566962 | 8.32195939738553e-08 | 0.420680825677036 | 0.000711104935483389 | 0.27340686829544 |
| CER | ADediting_750443 | chr19_40230996_- | 0.00737851488152048 | 0.217947607867876 | 1.75589385412954e-07 | 0.410939651861808 | 0.00181265325299185 | 0.252660106925802 |
| CER | ADediting_750505 | chr19_40269053_- | 0.0182971658185624 | 0.192461650700387 | 9.30171724116544e-05 | 0.31363102747839 | 0.0704758800309969 | 0.148114497390075 |
| DLPFC | ADediting_750507 | chr19_40270594_- | 1.0187840949892e-09 | 0.337931627852848 | 8.76626514916469e-05 | 0.220912619145436 | 0.000144246911548409 | 0.214223346271854 |
| CER | ADediting_750512 | chr19_40271375_- | 0.00143227501177983 | 0.258040328100426 | 4.51968703715761e-05 | 0.326614050383158 | 0.0271187018868211 | 0.180455494855667 |
| CER | ADediting_750514 | chr19_40271383_- | 8.02509516996534e-05 | 0.316335239389768 | 7.15273297407209e-07 | 0.391732820632078 | 0.0299904887060908 | 0.177274447179963 |
| DLPFC | ADediting_750517 | chr19_40275821_- | 0.54873800251752 | 0.0341861073045499 | 0.650500421051671 | -0.0258325448164284 | 2.30150860962738e-08 | 0.310723074630617 |
| CER | ADediting_750579 | chr19_40276655_- | 0.00017374855896033 | 0.301888205796698 | 8.20466364108301e-05 | 0.315931519675233 | 0.99434604354088 | -0.000583470278231256 |
| CER | ADediting_750583 | chr19_40276759_- | 2.81564987752914e-09 | 0.461372031900156 | 1.15234604479822e-09 | 0.471273935785955 | 0.0418973571561766 | 0.166351646648144 |
| CER | ADediting_750584 | chr19_40276771_- | 5.66934229362013e-06 | 0.361001578721527 | 2.40308650736809e-07 | 0.406752114938052 | 0.0828058647395503 | 0.142101274037451 |
| CER | ADediting_750586 | chr19_40276781_- | 1.37729944332974e-06 | 0.382340934168203 | 5.20259792191905e-07 | 0.396193144565716 | 0.0135783657837561 | 0.201148443694911 |
| CER | ADediting_750587 | chr19_40276811_- | 9.85130317549016e-06 | 0.352235751429719 | 3.87165696975437e-07 | 0.400275561552506 | 0.294311329378775 | 0.0861884174288199 |
| CER | ADediting_750591 | chr19_40276851_- | 1.09019629821839e-06 | 0.385725250408856 | 1.13665057151652e-05 | 0.349922969899596 | 0.161434749724467 | 0.114913139798451 |
| CER | ADediting_750593 | chr19_40276895_- | 1.35223087795701e-07 | 0.414382797786329 | 1.27940099738881e-05 | 0.347996638022101 | 0.321979749873406 | 0.0814123622837031 |
| CER | ADediting_750594 | chr19_40276899_- | 3.11789795503815e-06 | 0.370204936853308 | 6.05224644219437e-05 | 0.321432871912069 | 0.0583282519731423 | 0.15494229131269 |
| CER | ADediting_750595 | chr19_40276901_- | 1.01021020099354e-05 | 0.351830662182681 | 6.38696902929321e-05 | 0.320467324561243 | 0.00743168097543263 | 0.217756707378293 |
| CER | ADediting_750596 | chr19_40276904_- | 0.0079583348981539 | 0.215928445428119 | 0.000154044815120056 | 0.304189035834297 | 0.122376699007695 | 0.126689454988476 |
| CER | ADediting_750597 | chr19_40276911_- | 6.31423456706622e-09 | 0.452140947702154 | 4.99995308761423e-07 | 0.396745253911851 | 0.00587653629930019 | 0.223921410951362 |
| CER | ADediting_750598 | chr19_40276923_- | 3.57474770276971e-05 | 0.330709227867388 | 0.000291247330787392 | 0.291790597563581 | 0.00673949794188281 | 0.220343131168572 |
| CER | ADediting_750599 | chr19_40276928_- | 1.89801907380698e-05 | 0.34148146230659 | 4.79565370367856e-05 | 0.325569941651665 | 0.00132775914333773 | 0.259747565284291 |
| CER | ADediting_750600 | chr19_40276954_- | 0.000180121197835157 | 0.3011959357492 | 7.85109552935091e-05 | 0.316734583926192 | 0.260988161788741 | 0.0923552923203242 |
| CER | ADediting_750601 | chr19_40276973_- | 1.53153846585979e-07 | 0.412746360250347 | 0.000109400274873519 | 0.310629097391647 | 0.00942413028639188 | 0.211352537293276 |
| CER | ADediting_750605 | chr19_40276997_- | 1.72529222765562e-08 | 0.440254638468686 | 3.89028088889215e-09 | 0.457709675936441 | 0.00385710018045806 | 0.23459705851315 |
| CER | ADediting_750606 | chr19_40277001_- | 6.58364499291172e-07 | 0.392900753782708 | 1.45632704775651e-06 | 0.381527573694669 | 0.0168681286711719 | 0.194863526355158 |
| TCX | ADediting_750615 | chr19_40282633_- | 8.92263943750159e-05 | 0.314395813734767 | 0.10646812595346 | 0.132331562414288 | 0.00619170613561792 | 0.222563357815399 |
| TCX | ADediting_750616 | chr19_40282634_- | 2.17209044435239e-05 | 0.339219699085581 | 0.00140389048300379 | 0.258492432075983 | 0.795343694191858 | -0.0213543389869226 |
| TCX | ADediting_750619 | chr19_40284063_- | 0.000116384096690653 | 0.309475512702817 | 0.00477142615559677 | 0.22926191544095 | 0.979467112893794 | 0.00211914247205904 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 2.83811242801087e-29 | 0.58009956510318 | 3.14330142794933e-34 | 0.619388617485747 | 2.78393091056984e-21 | 0.502973709175825 |
| AC | 3.81888220537003e-40 | 0.713196692274745 | 7.76143630582226e-23 | 0.568869647548279 | 6.44716219308071e-36 | 0.684614170222963 |
| PCC | 3.40642498728607e-09 | 0.411303793627905 | 3.00422582470433e-07 | 0.360524347381373 | 1.00010563669102e-15 | 0.538046589805286 |
| CER | 1.37499803372788e-23 | 0.702128542157103 | 2.06556017320575e-30 | 0.767780556095248 | 1.01777865606894e-06 | 0.386713198320506 |
| TCX | 2.75658613955219e-08 | 0.434553807788018 | 0.0434237307207748 | 0.165148025003948 | 2.69307610800757e-15 | 0.587597217036485 |
| FP | 3.25580236431669e-13 | 0.510725807090794 | 1.79370423995391e-05 | 0.315459368718633 | 1.90815757332651e-16 | 0.565702862939318 |
| IFG | 0.000202272498331769 | 0.676932705721927 | 3.15707527517486e-05 | 0.732332066618214 | 0.000486288181692528 | 0.645998945432299 |
| PG | 0.0164047550797998 | 0.175773424926655 | 3.86375338002708e-05 | 0.296929231884669 | 5.11234291186814e-06 | 0.327314235300318 |
| STG | 0.000169332422952153 | 0.399131925883995 | 0.0275962103014216 | 0.240429649511864 | 7.38644449229786e-07 | 0.509610608047164 |
Top |
Relation with AD stages for AKT2 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_750420 | chr19_40230808_- | 9.80304268283688e-06 | 0.411259233568046 |
| CER | ADediting_750423 | chr19_40230823_- | 0.00152632383591192 | 0.30138054899004 |
| CER | ADediting_750425 | chr19_40230859_- | 0.000135230981124691 | 0.359114334693317 |
| CER | ADediting_750426 | chr19_40230860_- | 0.000276218063915094 | 0.343236419126139 |
| CER | ADediting_750428 | chr19_40230878_- | 0.00142444856724563 | 0.303193966502748 |
| CER | ADediting_750432 | chr19_40230895_- | 0.000857117463415475 | 0.316189445505934 |
| CER | ADediting_750439 | chr19_40230922_- | 0.00108961269200083 | 0.310122124867653 |
| CER | ADediting_750442 | chr19_40230995_- | 0.00104805408184233 | 0.311113861565795 |
| CER | ADediting_750443 | chr19_40230996_- | 0.000151029981372003 | 0.356711824063012 |
| CER | ADediting_750571 | chr19_40276598_- | 0.000914226316944904 | 0.314571211667509 |
| CER | ADediting_750603 | chr19_40276985_- | 0.000814484848782687 | 0.317463055390945 |
| CER | ADediting_750605 | chr19_40276997_- | 0.000854443007122826 | 0.316267620584209 |
| IFG | ADediting_750615 | chr19_40282633_- | 0.0354713369979928 | 0.422303326441651 |
| STG | ADediting_750618 | chr19_40283417_- | 0.00308942868559452 | 0.31911632270369 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 5.04013535410002e-09 | 0.525986134679791 |
| TCX | 2.46729142049422e-08 | 0.509329454597907 |
Top |
RelatedDrugs for AKT2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for AKT2 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| AKT2 | C0011860 | Diabetes Mellitus, Non-Insulin-Dependent | 2 | CTD_human;UNIPROT |
| AKT2 | C1852091 | INSULIN RESISTANCE, SUSCEPTIBILITY TO | 2 | UNIPROT |
| AKT2 | C4017238 | DIABETES MELLITUS, TYPE 2, PROTECTION AGAINST | 2 | UNIPROT |
| AKT2 | C0005586 | Bipolar Disorder | 1 | PSYGENET |
| AKT2 | C0006142 | Malignant neoplasm of breast | 1 | CGI;CTD_human |
| AKT2 | C0271694 | Familial partial lipodystrophy | 1 | CTD_human |
| AKT2 | C0678222 | Breast Carcinoma | 1 | CGI;CTD_human |
| AKT2 | C1257931 | Mammary Neoplasms, Human | 1 | CTD_human |
| AKT2 | C1458155 | Mammary Neoplasms | 1 | CTD_human |
| AKT2 | C1720859 | Familial Partial Lipodystrophy, Type 1 | 1 | CTD_human |
| AKT2 | C1720860 | Familial Partial Lipodystrophy, Type 2 | 1 | CTD_human |
| AKT2 | C1720861 | Familial Partial Lipodystrophy, Type 3 | 1 | CTD_human |
| AKT2 | C2931822 | Nasopharyngeal carcinoma | 1 | CTD_human |
| AKT2 | C3278384 | HYPOINSULINEMIC HYPOGLYCEMIA WITH HEMIHYPERTROPHY | 1 | CTD_human;ORPHANET;UNIPROT |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|