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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for NR2F6

check button Gene summary
Gene informationGene symbol

NR2F6

Gene ID

2063

Gene namenuclear receptor subfamily 2 group F member 6
SynonymsEAR-2|EAR2|ERBAL2
Cytomap

19p13.11

Type of geneprotein-coding
Descriptionnuclear receptor subfamily 2 group F member 6ERBA-related gene-2V-erbA-related protein 2nuclear receptor V-erbA-relatedv-erb-a avian erythroblastic leukemia viral oncogene homolog-like 2
Modification date20200313
UniProtAcc

P10588,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
NR2F6

GO:0000122

negative regulation of transcription by RNA polymerase II

10644740


Top

RNA A-to-I events for NR2F6

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_720537(17232794, -), ADediting_720538(17232809, -), ADediting_720539(17232829, -), ADediting_720540(17232832, -), ADediting_720541(17232891, -), ADediting_720542(17232913, -), ADediting_720543(17232985, -), ADediting_720544(17232997, -), ADediting_720545(17233000, -), ADediting_720546(17233001, -), ADediting_720547(17233021, -), ADediting_720548(17233037, -), ADediting_720549(17233141, -), ADediting_720550(17233306, -), ADediting_720551(17233538, -), ADediting_720552(17233557, -), ADediting_720553(17233583, -), ADediting_720554(17233593, -), ADediting_720555(17233599, -), ADediting_720556(17233602, -), ADediting_720557(17233603, -), ADediting_720558(17233608, -), ADediting_720559(17233634, -), ADediting_720560(17233635, -), ADediting_720561(17233661, -), ADediting_720562(17233664, -), ADediting_720563(17233665, -), ADediting_720564(17233666, -), ADediting_720565(17233676, -), ADediting_720566(17233679, -), ADediting_720567(17233695, -), ADediting_720568(17233714, -), ADediting_720569(17233723, -), ADediting_720570(17233728, -), ADediting_720571(17233738, -), ADediting_720572(17233763, -), ADediting_720573(17233768, -), ADediting_720574(17233769, -), ADediting_720575(17233990, -), ADediting_720576(17234075, -), ADediting_720577(17234101, -), ADediting_720578(17234123, -), ADediting_720579(17234136, -), ADediting_720580(17234140, -), ADediting_720581(17234160, -), ADediting_720582(17234182, -), ADediting_720583(17234215, -), ADediting_720584(17234301, -), ADediting_720585(17234304, -), ADediting_720586(17234323, -), ADediting_720587(17234358, -), ADediting_720588(17234363, -), ADediting_720589(17234368, -), ADediting_720590(17234386, -), ADediting_720591(17234390, -), ADediting_720592(17234601, -), ADediting_720593(17234607, -), ADediting_720594(17234608, -), ADediting_720595(17234609, -), ADediting_720596(17234617, -), ADediting_720597(17234733, -), ADediting_720598(17234773, -), ADediting_720599(17234837, -), ADediting_720600(17237435, -), ADediting_720601(17237443, -), ADediting_720602(17237479, -), ADediting_720603(17237484, -), ADediting_720604(17237488, -), ADediting_720605(17237509, -), ADediting_720606(17237514, -), ADediting_720607(17237517, -), ADediting_720608(17237523, -), ADediting_720609(17237540, -), ADediting_720610(17237544, -), ADediting_720611(17237549, -), ADediting_720612(17237560, -), ADediting_720613(17237576, -), ADediting_720614(17237588, -), ADediting_720615(17237594, -), ADediting_720616(17237613, -), ADediting_720617(17237615, -), ADediting_720618(17237630, -), ADediting_720619(17237647, -), ADediting_720620(17237677, -), ADediting_720621(17237682, -), ADediting_720622(17237683, -), ADediting_720623(17237705, -), ADediting_720624(17237889, -), ADediting_720625(17237905, -), ADediting_720626(17237984, -), ADediting_720627(17238016, -), ADediting_720628(17238018, -), ADediting_720629(17238023, -), ADediting_720630(17238028, -), ADediting_720631(17238040, -), ADediting_720632(17238045, -), ADediting_720633(17238053, -), ADediting_720634(17238058, -), ADediting_720635(17238071, -), ADediting_720636(17238083, -), ADediting_720637(17238107, -), ADediting_720638(17238130, -), ADediting_720639(17238896, -), ADediting_720640(17239037, -), ADediting_1553176(17232841, -), ADediting_1553177(17232943, -), ADediting_1553178(17232982, -), ADediting_1553179(17233084, -), ADediting_1553180(17233085, -), ADediting_1553181(17233192, -), ADediting_1553182(17233205, -), ADediting_1553183(17233222, -), ADediting_1553184(17233625, -), ADediting_1553185(17233629, -), ADediting_1553186(17234371, -), ADediting_1553187(17234404, -), ADediting_1553188(17234736, -), ADediting_1553189(17234743, -), ADediting_1553190(17234797, -), ADediting_1553191(17236526, -), ADediting_1553192(17237495, -), ADediting_1553193(17237508, -), ADediting_1553194(17237520, -), ADediting_1553195(17237606, -), ADediting_1553196(17237918, -), ADediting_1553197(17237935, -), ADediting_1553198(17237936, -), ADediting_1553199(17237948, -), ADediting_1553200(17237974, -), ADediting_1553201(17237991, -), ADediting_1553202(17237992, -), ADediting_1553203(17238078, -), ADediting_1553204(17238088, -),

Top

RNA editing positional annotations for NR2F6 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_720537chr19_17232794_-intronic
ADediting_720538chr19_17232809_-intronic
ADediting_720539chr19_17232829_-intronic
ADediting_720540chr19_17232832_-intronic
ADediting_720541chr19_17232891_-intronic
ADediting_720542chr19_17232913_-intronic
ADediting_720543chr19_17232985_-intronic
ADediting_720544chr19_17232997_-intronic
ADediting_720545chr19_17233000_-intronic
ADediting_720546chr19_17233001_-intronic
ADediting_720547chr19_17233021_-intronic
ADediting_720548chr19_17233037_-intronic
ADediting_720549chr19_17233141_-intronic
ADediting_720550chr19_17233306_-intronic
ADediting_720551chr19_17233538_-intronic
ADediting_720552chr19_17233557_-intronic
ADediting_720553chr19_17233583_-intronic
ADediting_720554chr19_17233593_-intronic
ADediting_720555chr19_17233599_-intronic
ADediting_720556chr19_17233602_-intronic
ADediting_720557chr19_17233603_-intronic
ADediting_720558chr19_17233608_-intronic
ADediting_720559chr19_17233634_-intronic
ADediting_720560chr19_17233635_-intronic
ADediting_720561chr19_17233661_-intronic
ADediting_720562chr19_17233664_-intronic
ADediting_720563chr19_17233665_-intronic
ADediting_720564chr19_17233666_-intronic
ADediting_720565chr19_17233676_-intronic
ADediting_720566chr19_17233679_-intronic
ADediting_720567chr19_17233695_-intronic
ADediting_720568chr19_17233714_-intronic
ADediting_720569chr19_17233723_-intronic
ADediting_720570chr19_17233728_-intronic
ADediting_720571chr19_17233738_-intronic
ADediting_720572chr19_17233763_-intronic
ADediting_720573chr19_17233768_-intronic
ADediting_720574chr19_17233769_-intronic
ADediting_720575chr19_17233990_-intronic
ADediting_720576chr19_17234075_-intronic
ADediting_720577chr19_17234101_-intronic
ADediting_720578chr19_17234123_-intronic
ADediting_720579chr19_17234136_-intronic
ADediting_720580chr19_17234140_-intronic
ADediting_720581chr19_17234160_-intronic
ADediting_720582chr19_17234182_-intronic
ADediting_720583chr19_17234215_-intronic
ADediting_720584chr19_17234301_-intronic
ADediting_720585chr19_17234304_-intronic
ADediting_720586chr19_17234323_-intronic
ADediting_720587chr19_17234358_-intronic
ADediting_720588chr19_17234363_-intronic
ADediting_720589chr19_17234368_-intronic
ADediting_720590chr19_17234386_-intronic
ADediting_720591chr19_17234390_-intronic
ADediting_720592chr19_17234601_-intronic
ADediting_720593chr19_17234607_-intronic
ADediting_720594chr19_17234608_-intronic
ADediting_720595chr19_17234609_-intronic
ADediting_720596chr19_17234617_-intronic
ADediting_720597chr19_17234733_-intronic
ADediting_720598chr19_17234773_-intronic
ADediting_720599chr19_17234837_-intronic
ADediting_720600chr19_17237435_-intronic
ADediting_720601chr19_17237443_-intronic
ADediting_720602chr19_17237479_-intronic
ADediting_720603chr19_17237484_-intronic
ADediting_720604chr19_17237488_-intronic
ADediting_720605chr19_17237509_-intronic
ADediting_720606chr19_17237514_-intronic
ADediting_720607chr19_17237517_-intronic
ADediting_720608chr19_17237523_-intronic
ADediting_720609chr19_17237540_-intronic
ADediting_720610chr19_17237544_-intronic
ADediting_720611chr19_17237549_-intronic
ADediting_720612chr19_17237560_-intronic
ADediting_720613chr19_17237576_-intronic
ADediting_720614chr19_17237588_-intronic
ADediting_720615chr19_17237594_-intronic
ADediting_720616chr19_17237613_-intronic
ADediting_720617chr19_17237615_-intronic
ADediting_720618chr19_17237630_-intronic
ADediting_720619chr19_17237647_-intronic
ADediting_720620chr19_17237677_-intronic
ADediting_720621chr19_17237682_-intronic
ADediting_720622chr19_17237683_-intronic
ADediting_720623chr19_17237705_-intronic
ADediting_720624chr19_17237889_-intronic
ADediting_720625chr19_17237905_-intronic
ADediting_720626chr19_17237984_-intronic
ADediting_720627chr19_17238016_-intronic
ADediting_720628chr19_17238018_-intronic
ADediting_720629chr19_17238023_-intronic
ADediting_720630chr19_17238028_-intronic
ADediting_720631chr19_17238040_-intronic
ADediting_720632chr19_17238045_-intronic
ADediting_720633chr19_17238053_-intronic
ADediting_720634chr19_17238058_-intronic
ADediting_720635chr19_17238071_-intronic
ADediting_720636chr19_17238083_-intronic
ADediting_720637chr19_17238107_-intronic
ADediting_720638chr19_17238130_-intronic
ADediting_720639chr19_17238896_-intronic
ADediting_720640chr19_17239037_-intronic
ADediting_1553176chr19_17232841_-intronic
ADediting_1553177chr19_17232943_-intronic
ADediting_1553178chr19_17232982_-intronic
ADediting_1553179chr19_17233084_-intronic
ADediting_1553180chr19_17233085_-intronic
ADediting_1553181chr19_17233192_-intronic
ADediting_1553182chr19_17233205_-intronic
ADediting_1553183chr19_17233222_-intronic
ADediting_1553184chr19_17233625_-intronic
ADediting_1553185chr19_17233629_-intronic
ADediting_1553186chr19_17234371_-intronic
ADediting_1553187chr19_17234404_-intronic
ADediting_1553188chr19_17234736_-intronic
ADediting_1553189chr19_17234743_-intronic
ADediting_1553190chr19_17234797_-intronic
ADediting_1553191chr19_17236526_-intronic
ADediting_1553192chr19_17237495_-intronic
ADediting_1553193chr19_17237508_-intronic
ADediting_1553194chr19_17237520_-intronic
ADediting_1553195chr19_17237606_-intronic
ADediting_1553196chr19_17237918_-intronic
ADediting_1553197chr19_17237935_-intronic
ADediting_1553198chr19_17237936_-intronic
ADediting_1553199chr19_17237948_-intronic
ADediting_1553200chr19_17237974_-intronic
ADediting_1553201chr19_17237991_-intronic
ADediting_1553202chr19_17237992_-intronic
ADediting_1553203chr19_17238078_-intronic
ADediting_1553204chr19_17238088_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_720537chr19_17232794_-SINEAluName=AluJr
ADediting_720538chr19_17232809_-SINEAluName=AluJr
ADediting_720539chr19_17232829_-SINEAluName=AluJr
ADediting_720540chr19_17232832_-SINEAluName=AluJr
ADediting_720541chr19_17232891_-SINEAluName=AluSz
ADediting_720542chr19_17232913_-SINEAluName=AluSz
ADediting_720543chr19_17232985_-SINEAluName=AluSz
ADediting_720544chr19_17232997_-SINEAluName=AluSz
ADediting_720545chr19_17233000_-SINEAluName=AluSz
ADediting_720546chr19_17233001_-SINEAluName=AluSz
ADediting_720547chr19_17233021_-SINEAluName=AluSz
ADediting_720548chr19_17233037_-SINEAluName=AluSz
ADediting_720549chr19_17233141_-SINEAluName=AluSz
ADediting_720550chr19_17233306_-SINEAluName=AluJr
ADediting_720551chr19_17233538_-SINEAluName=AluSz6
ADediting_720552chr19_17233557_-SINEAluName=AluSz6
ADediting_720553chr19_17233583_-SINEAluName=AluSz6
ADediting_720554chr19_17233593_-SINEAluName=AluSz6
ADediting_720555chr19_17233599_-SINEAluName=AluSz6
ADediting_720556chr19_17233602_-SINEAluName=AluSz6
ADediting_720557chr19_17233603_-SINEAluName=AluSz6
ADediting_720558chr19_17233608_-SINEAluName=AluSz6
ADediting_720559chr19_17233634_-SINEAluName=AluSz6
ADediting_720560chr19_17233635_-SINEAluName=AluSz6
ADediting_720561chr19_17233661_-SINEAluName=AluSz6
ADediting_720562chr19_17233664_-SINEAluName=AluSz6
ADediting_720563chr19_17233665_-SINEAluName=AluSz6
ADediting_720564chr19_17233666_-SINEAluName=AluSz6
ADediting_720565chr19_17233676_-SINEAluName=AluSz6
ADediting_720566chr19_17233679_-SINEAluName=AluSz6
ADediting_720567chr19_17233695_-SINEAluName=AluSz6
ADediting_720568chr19_17233714_-SINEAluName=AluSz6
ADediting_720569chr19_17233723_-SINEAluName=AluSz6
ADediting_720570chr19_17233728_-SINEAluName=AluSz6
ADediting_720571chr19_17233738_-SINEAluName=AluSz6
ADediting_720572chr19_17233763_-SINEAluName=AluSz6
ADediting_720573chr19_17233768_-SINEAluName=AluSz6
ADediting_720574chr19_17233769_-SINEAluName=AluSz6
ADediting_720575chr19_17233990_-SINEAluName=AluSg
ADediting_720576chr19_17234075_-SINEAluName=AluSg
ADediting_720577chr19_17234101_-SINEAluName=AluSg
ADediting_720578chr19_17234123_-SINEAluName=AluSg
ADediting_720579chr19_17234136_-SINEAluName=AluSg
ADediting_720580chr19_17234140_-SINEAluName=AluSg
ADediting_720581chr19_17234160_-SINEAluName=AluSg
ADediting_720582chr19_17234182_-SINEAluName=AluSg
ADediting_720583chr19_17234215_-SINEAluName=AluSg
ADediting_720584chr19_17234301_-SINEAluName=FRAM
ADediting_720585chr19_17234304_-SINEAluName=FRAM
ADediting_720586chr19_17234323_-SINEAluName=FRAM
ADediting_720587chr19_17234358_-SINEAluName=FRAM
ADediting_720588chr19_17234363_-SINEAluName=FRAM
ADediting_720589chr19_17234368_-SINEAluName=FRAM
ADediting_720590chr19_17234386_-SINEAluName=FRAM
ADediting_720591chr19_17234390_-SINEAluName=FRAM
ADediting_720592chr19_17234601_-SINEAluName=AluJb
ADediting_720593chr19_17234607_-SINEAluName=AluJb
ADediting_720594chr19_17234608_-SINEAluName=AluJb
ADediting_720595chr19_17234609_-SINEAluName=AluJb
ADediting_720596chr19_17234617_-SINEAluName=AluJb
ADediting_720597chr19_17234733_-SINEAluName=AluJb
ADediting_720598chr19_17234773_-SINEAluName=AluJb
ADediting_720599chr19_17234837_-SINEAluName=AluJb
ADediting_720600chr19_17237435_-SINEAluName=AluSc5
ADediting_720601chr19_17237443_-SINEAluName=AluSc5
ADediting_720602chr19_17237479_-SINEAluName=AluSc5
ADediting_720603chr19_17237484_-SINEAluName=AluSc5
ADediting_720604chr19_17237488_-SINEAluName=AluSc5
ADediting_720605chr19_17237509_-SINEAluName=AluSc5
ADediting_720606chr19_17237514_-SINEAluName=AluSc5
ADediting_720607chr19_17237517_-SINEAluName=AluSc5
ADediting_720608chr19_17237523_-SINEAluName=AluSc5
ADediting_720609chr19_17237540_-SINEAluName=AluSc5
ADediting_720610chr19_17237544_-SINEAluName=AluSc5
ADediting_720611chr19_17237549_-SINEAluName=AluSc5
ADediting_720612chr19_17237560_-SINEAluName=AluSc5
ADediting_720613chr19_17237576_-SINEAluName=AluSc5
ADediting_720614chr19_17237588_-SINEAluName=AluSc5
ADediting_720615chr19_17237594_-SINEAluName=AluSc5
ADediting_720616chr19_17237613_-SINEAluName=AluSc5
ADediting_720617chr19_17237615_-SINEAluName=AluSc5
ADediting_720618chr19_17237630_-SINEAluName=AluSc5
ADediting_720619chr19_17237647_-SINEAluName=AluSc5
ADediting_720620chr19_17237677_-SINEAluName=AluSc5
ADediting_720621chr19_17237682_-SINEAluName=AluSc5
ADediting_720622chr19_17237683_-SINEAluName=AluSc5
ADediting_720623chr19_17237705_-SINEAluName=AluSc5
ADediting_720624chr19_17237889_-SINEAluName=AluJo
ADediting_720625chr19_17237905_-SINEAluName=AluJo
ADediting_720626chr19_17237984_-SINEAluName=AluJo
ADediting_720627chr19_17238016_-SINEAluName=AluJo
ADediting_720628chr19_17238018_-SINEAluName=AluJo
ADediting_720629chr19_17238023_-SINEAluName=AluJo
ADediting_720630chr19_17238028_-SINEAluName=AluJo
ADediting_720631chr19_17238040_-SINEAluName=AluJo
ADediting_720632chr19_17238045_-SINEAluName=AluJo
ADediting_720633chr19_17238053_-SINEAluName=AluJo
ADediting_720634chr19_17238058_-SINEAluName=AluJo
ADediting_720635chr19_17238071_-SINEAluName=AluJo
ADediting_720636chr19_17238083_-SINEAluName=AluJo
ADediting_720637chr19_17238107_-SINEAluName=AluJo
ADediting_720638chr19_17238130_-SINEAluName=AluJo
ADediting_720639chr19_17238896_-SINEAluName=FLAM_C
ADediting_720640chr19_17239037_-SINEAluName=AluSx
ADediting_1553176chr19_17232841_-SINEAluName=AluJr
ADediting_1553177chr19_17232943_-SINEAluName=AluSz
ADediting_1553178chr19_17232982_-SINEAluName=AluSz
ADediting_1553179chr19_17233084_-SINEAluName=AluSz
ADediting_1553180chr19_17233085_-SINEAluName=AluSz
ADediting_1553181chr19_17233192_-SINEAluName=AluJr
ADediting_1553182chr19_17233205_-SINEAluName=AluJr
ADediting_1553183chr19_17233222_-SINEAluName=AluJr
ADediting_1553184chr19_17233625_-SINEAluName=AluSz6
ADediting_1553185chr19_17233629_-SINEAluName=AluSz6
ADediting_1553186chr19_17234371_-SINEAluName=FRAM
ADediting_1553187chr19_17234404_-SINEAluName=FRAM
ADediting_1553188chr19_17234736_-SINEAluName=AluJb
ADediting_1553189chr19_17234743_-SINEAluName=AluJb
ADediting_1553190chr19_17234797_-SINEAluName=AluJb
ADediting_1553192chr19_17237495_-SINEAluName=AluSc5
ADediting_1553193chr19_17237508_-SINEAluName=AluSc5
ADediting_1553194chr19_17237520_-SINEAluName=AluSc5
ADediting_1553195chr19_17237606_-SINEAluName=AluSc5
ADediting_1553196chr19_17237918_-SINEAluName=AluJo
ADediting_1553197chr19_17237935_-SINEAluName=AluJo
ADediting_1553198chr19_17237936_-SINEAluName=AluJo
ADediting_1553199chr19_17237948_-SINEAluName=AluJo
ADediting_1553200chr19_17237974_-SINEAluName=AluJo
ADediting_1553201chr19_17237991_-SINEAluName=AluJo
ADediting_1553202chr19_17237992_-SINEAluName=AluJo
ADediting_1553203chr19_17238078_-SINEAluName=AluJo
ADediting_1553204chr19_17238088_-SINEAluName=AluJo

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RNA A-to-I editing events in the alternative splicing sites for NR2F6

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for NR2F6

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for NR2F6

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for NR2F6


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1097295chr3_85385762_+ENSG00000160113.5ENST00000291442.3NR2F6-201hsa-miR-5688chr1917232204172322107mer-m81723220317232224145-13.9

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for NR2F6

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for NR2F6

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_720552chr19_17233557_-0.03505995019425890.1197599967488820.5025362564355360.03822258629209481.98651995529404e-130.401373074375558
CERADediting_720552chr19_17233557_-0.08972506181008250.1390365511925580.0001254034982243720.3080777557449360.936279313685380.00658265139605166
DLPFCADediting_720553chr19_17233583_-0.01433303437696570.1389687674494710.7586316286900410.01752167232559768.09377940446039e-190.474593266405972
DLPFCADediting_720569chr19_17233723_-0.003077895371253380.1675945931962580.07908162805680820.09989029695664973.53173158064736e-100.346602020829911
DLPFCADediting_720570chr19_17233728_-0.0004825300216099770.1970825396854470.01059792287607130.1449711682701921.45244130684164e-090.334968316271445
DLPFCADediting_720571chr19_17233738_-0.009104654272888250.1479119666276940.1946372666949540.07386137304954193.04307140472313e-110.365705768421065
CERADediting_720575chr19_17233990_-0.01233011143819550.2038871520574631.3525288847871e-050.3470872033934560.6616680555509180.0360205444911052
CERADediting_720584chr19_17234301_-0.003232037411536630.2389447847960385.68329536636175e-050.3225569416532590.2712549817319890.0904012600104989
DLPFCADediting_720588chr19_17234363_-0.00508562626496580.1587489601143150.994549594729150.0003895554175812511.72557966014326e-260.555433864492769
CERADediting_720590chr19_17234386_-0.005650321961335170.2249368132205896.24858295582651e-050.3208606288835870.2422298478912470.0960663009728239

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC5.72278093810998e-150.42416771851199.67957624475105e-180.4612966514660042.21660266073514e-270.563557710495744
AC6.58756891883291e-200.5349334165687663.34516534787621e-230.5728448984308431.10012996496464e-170.506353567037541
PCC1.18174159563744e-140.5205086347501195.87658386340726e-230.6350231409882440.0001193531703165190.274816357335481
CER0.006508140137328910.221260482313471.75478983131249e-110.5138591033195340.03999307674723630.167905888471243
TCX2.38596351908194e-060.3742333096857589.23857576330884e-160.5954467252298970.134694500621015-0.122699548046135
FP2.64695888254085e-100.451037494326176.7643382182221e-110.4641617615812671.63535775672326e-050.31688781226888
IFG9.80316886095139e-060.7615132105774394.34300679159648e-090.8847823531538250.2553947490651660.236327248241842
STG1.7316987400192e-140.7168829663862611.09955836553894e-100.63240886709450.005320807557810990.301488019656134

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Relation with AD stages for NR2F6

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.

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RelatedDrugs for NR2F6

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for NR2F6

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource
NR2F6C0006142Malignant neoplasm of breast1CTD_human
NR2F6C0014175Endometriosis1CTD_human
NR2F6C0269102Endometrioma1CTD_human
NR2F6C0678222Breast Carcinoma1CTD_human
NR2F6C1257931Mammary Neoplasms, Human1CTD_human
NR2F6C1458155Mammary Neoplasms1CTD_human