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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for ZNF385C

check button Gene summary
Gene informationGene symbol

ZNF385C

Gene ID

201181

Gene namezinc finger protein 385C
Synonyms-
Cytomap

17q21.2

Type of geneprotein-coding
Descriptionzinc finger protein 385CCTD-2132N18.2CTD-2132N18.4
Modification date20200327
UniProtAcc

Q66K41,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for ZNF385C

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_621374(42035746, -), ADediting_621376(42044123, -), ADediting_621377(42044189, -), ADediting_621378(42044210, -), ADediting_621379(42044232, -), ADediting_621380(42044258, -), ADediting_621381(42044274, -), ADediting_621382(42044289, -), ADediting_621383(42044360, -), ADediting_621384(42044434, -), ADediting_621385(42044451, -), ADediting_621386(42044454, -), ADediting_621387(42044494, -), ADediting_621388(42044504, -), ADediting_621389(42044575, -), ADediting_621390(42044577, -), ADediting_621391(42044985, -), ADediting_621392(42044986, -), ADediting_621393(42045014, -), ADediting_621394(42045050, -), ADediting_621395(42045056, -), ADediting_621396(42045082, -), ADediting_621397(42045189, -), ADediting_621398(42045190, -), ADediting_621399(42045198, -), ADediting_621400(42045280, -), ADediting_621401(42045323, -), ADediting_621402(42045324, -), ADediting_621403(42046334, -), ADediting_621404(42046336, -), ADediting_621405(42046341, -), ADediting_621406(42046348, -), ADediting_621407(42046349, -), ADediting_621408(42046350, -), ADediting_621409(42046363, -), ADediting_621410(42046373, -), ADediting_621411(42046420, -), ADediting_621412(42046465, -), ADediting_621413(42046468, -), ADediting_621414(42046476, -), ADediting_621415(42046478, -), ADediting_621416(42046488, -), ADediting_621417(42046500, -), ADediting_621418(42046505, -), ADediting_621419(42046517, -), ADediting_621420(42046531, -), ADediting_621421(42046548, -), ADediting_621422(42046930, -), ADediting_621423(42046978, -), ADediting_621424(42046991, -), ADediting_621425(42047000, -), ADediting_621426(42047001, -), ADediting_621427(42047011, -), ADediting_621428(42047027, -), ADediting_621429(42047038, -), ADediting_621430(42047128, -), ADediting_621431(42047143, -), ADediting_621432(42047160, -), ADediting_621433(42047237, -), ADediting_621434(42047304, -), ADediting_621435(42047305, -), ADediting_621436(42047337, -), ADediting_621437(42047442, -), ADediting_621438(42047447, -), ADediting_621439(42047448, -), ADediting_621440(42047683, -), ADediting_621441(42047689, -), ADediting_621442(42047708, -), ADediting_621443(42047746, -), ADediting_621444(42047750, -), ADediting_621445(42047765, -), ADediting_621446(42047778, -), ADediting_621447(42047791, -), ADediting_621448(42047818, -), ADediting_621449(42047920, -), ADediting_621450(42047925, -), ADediting_621451(42047926, -), ADediting_621452(42047928, -), ADediting_621453(42048281, -), ADediting_621454(42048287, -), ADediting_621455(42048304, -), ADediting_621456(42048321, -), ADediting_621457(42048322, -), ADediting_621458(42048336, -), ADediting_621459(42048356, -), ADediting_621460(42048367, -), ADediting_621461(42048371, -), ADediting_621462(42048372, -), ADediting_621463(42048373, -), ADediting_621464(42048433, -), ADediting_621465(42048445, -), ADediting_621466(42048462, -), ADediting_621467(42048463, -), ADediting_621468(42048491, -), ADediting_621469(42048507, -), ADediting_621470(42048525, -), ADediting_621471(42048541, -), ADediting_1546480(42038988, -), ADediting_1546481(42044059, -), ADediting_1546482(42044114, -), ADediting_1546483(42044199, -), ADediting_1546484(42045151, -), ADediting_1546485(42045246, -), ADediting_1546486(42046376, -), ADediting_1546487(42046426, -), ADediting_1546488(42046689, -), ADediting_1546489(42046915, -), ADediting_1546490(42047037, -), ADediting_1546491(42048309, -), ADediting_1546492(42048410, -), ADediting_1546493(42048421, -), ADediting_1546494(42048423, -), ADediting_1546495(42048501, -), ADediting_1546496(42048547, -), ADediting_1546497(42049919, -), ADediting_1546498(42054790, -), ADediting_1546499(42056532, -), ADediting_1546500(42056540, -), ADediting_1546501(42056544, -), ADediting_1546502(42057004, -), ADediting_1546503(42057079, -), ADediting_1546504(42057128, -), ADediting_1546505(42057131, -), ADediting_1546506(42057137, -), ADediting_1546507(42059279, -), ADediting_1546508(42059854, -), ADediting_1546509(42059868, -), ADediting_1546510(42061359, -), ADediting_1546511(42061365, -),

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RNA editing positional annotations for ZNF385C using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_621374chr17_42035746_-intronic
ADediting_621376chr17_42044123_-intronic
ADediting_621377chr17_42044189_-intronic
ADediting_621378chr17_42044210_-intronic
ADediting_621379chr17_42044232_-intronic
ADediting_621380chr17_42044258_-intronic
ADediting_621381chr17_42044274_-intronic
ADediting_621382chr17_42044289_-intronic
ADediting_621383chr17_42044360_-intronic
ADediting_621384chr17_42044434_-intronic
ADediting_621385chr17_42044451_-intronic
ADediting_621386chr17_42044454_-intronic
ADediting_621387chr17_42044494_-intronic
ADediting_621388chr17_42044504_-intronic
ADediting_621389chr17_42044575_-intronic
ADediting_621390chr17_42044577_-intronic
ADediting_621391chr17_42044985_-intronic
ADediting_621392chr17_42044986_-intronic
ADediting_621393chr17_42045014_-intronic
ADediting_621394chr17_42045050_-intronic
ADediting_621395chr17_42045056_-intronic
ADediting_621396chr17_42045082_-intronic
ADediting_621397chr17_42045189_-intronic
ADediting_621398chr17_42045190_-intronic
ADediting_621399chr17_42045198_-intronic
ADediting_621400chr17_42045280_-intronic
ADediting_621401chr17_42045323_-intronic
ADediting_621402chr17_42045324_-intronic
ADediting_621403chr17_42046334_-intronic
ADediting_621404chr17_42046336_-intronic
ADediting_621405chr17_42046341_-intronic
ADediting_621406chr17_42046348_-intronic
ADediting_621407chr17_42046349_-intronic
ADediting_621408chr17_42046350_-intronic
ADediting_621409chr17_42046363_-intronic
ADediting_621410chr17_42046373_-intronic
ADediting_621411chr17_42046420_-intronic
ADediting_621412chr17_42046465_-intronic
ADediting_621413chr17_42046468_-intronic
ADediting_621414chr17_42046476_-intronic
ADediting_621415chr17_42046478_-intronic
ADediting_621416chr17_42046488_-intronic
ADediting_621417chr17_42046500_-intronic
ADediting_621418chr17_42046505_-intronic
ADediting_621419chr17_42046517_-intronic
ADediting_621420chr17_42046531_-intronic
ADediting_621421chr17_42046548_-intronic
ADediting_621422chr17_42046930_-intronic
ADediting_621423chr17_42046978_-intronic
ADediting_621424chr17_42046991_-intronic
ADediting_621425chr17_42047000_-intronic
ADediting_621426chr17_42047001_-intronic
ADediting_621427chr17_42047011_-intronic
ADediting_621428chr17_42047027_-intronic
ADediting_621429chr17_42047038_-intronic
ADediting_621430chr17_42047128_-intronic
ADediting_621431chr17_42047143_-intronic
ADediting_621432chr17_42047160_-intronic
ADediting_621433chr17_42047237_-intronic
ADediting_621434chr17_42047304_-intronic
ADediting_621435chr17_42047305_-intronic
ADediting_621436chr17_42047337_-intronic
ADediting_621437chr17_42047442_-intronic
ADediting_621438chr17_42047447_-intronic
ADediting_621439chr17_42047448_-intronic
ADediting_621440chr17_42047683_-intronic
ADediting_621441chr17_42047689_-intronic
ADediting_621442chr17_42047708_-intronic
ADediting_621443chr17_42047746_-intronic
ADediting_621444chr17_42047750_-intronic
ADediting_621445chr17_42047765_-intronic
ADediting_621446chr17_42047778_-intronic
ADediting_621447chr17_42047791_-intronic
ADediting_621448chr17_42047818_-intronic
ADediting_621449chr17_42047920_-intronic
ADediting_621450chr17_42047925_-intronic
ADediting_621451chr17_42047926_-intronic
ADediting_621452chr17_42047928_-intronic
ADediting_621453chr17_42048281_-intronic
ADediting_621454chr17_42048287_-intronic
ADediting_621455chr17_42048304_-intronic
ADediting_621456chr17_42048321_-intronic
ADediting_621457chr17_42048322_-intronic
ADediting_621458chr17_42048336_-intronic
ADediting_621459chr17_42048356_-intronic
ADediting_621460chr17_42048367_-intronic
ADediting_621461chr17_42048371_-intronic
ADediting_621462chr17_42048372_-intronic
ADediting_621463chr17_42048373_-intronic
ADediting_621464chr17_42048433_-intronic
ADediting_621465chr17_42048445_-intronic
ADediting_621466chr17_42048462_-intronic
ADediting_621467chr17_42048463_-intronic
ADediting_621468chr17_42048491_-intronic
ADediting_621469chr17_42048507_-intronic
ADediting_621470chr17_42048525_-intronic
ADediting_621471chr17_42048541_-intronic
ADediting_1546480chr17_42038988_-UTR3
ADediting_1546481chr17_42044059_-intronic
ADediting_1546482chr17_42044114_-intronic
ADediting_1546483chr17_42044199_-intronic
ADediting_1546484chr17_42045151_-intronic
ADediting_1546485chr17_42045246_-intronic
ADediting_1546486chr17_42046376_-intronic
ADediting_1546487chr17_42046426_-intronic
ADediting_1546488chr17_42046689_-intronic
ADediting_1546489chr17_42046915_-intronic
ADediting_1546490chr17_42047037_-intronic
ADediting_1546491chr17_42048309_-intronic
ADediting_1546492chr17_42048410_-intronic
ADediting_1546493chr17_42048421_-intronic
ADediting_1546494chr17_42048423_-intronic
ADediting_1546495chr17_42048501_-intronic
ADediting_1546496chr17_42048547_-intronic
ADediting_1546497chr17_42049919_-intronic
ADediting_1546498chr17_42054790_-intronic
ADediting_1546499chr17_42056532_-intronic
ADediting_1546500chr17_42056540_-intronic
ADediting_1546501chr17_42056544_-intronic
ADediting_1546502chr17_42057004_-intronic
ADediting_1546503chr17_42057079_-intronic
ADediting_1546504chr17_42057128_-intronic
ADediting_1546505chr17_42057131_-intronic
ADediting_1546506chr17_42057137_-intronic
ADediting_1546507chr17_42059279_-intronic
ADediting_1546508chr17_42059854_-intronic
ADediting_1546509chr17_42059868_-intronic
ADediting_1546510chr17_42061359_-intronic
ADediting_1546511chr17_42061365_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_621374chr17_42035746_-SINEAluName=AluSx1
ADediting_621376chr17_42044123_-SINEAluName=AluJb
ADediting_621377chr17_42044189_-SINEAluName=AluJb
ADediting_621378chr17_42044210_-SINEAluName=AluJb
ADediting_621379chr17_42044232_-SINEAluName=AluJb
ADediting_621380chr17_42044258_-SINEAluName=AluJb
ADediting_621381chr17_42044274_-SINEAluName=AluJb
ADediting_621382chr17_42044289_-SINEAluName=AluJb
ADediting_621383chr17_42044360_-SINEAluName=AluSp
ADediting_621384chr17_42044434_-SINEAluName=AluSp
ADediting_621385chr17_42044451_-SINEAluName=AluSp
ADediting_621386chr17_42044454_-SINEAluName=AluSp
ADediting_621387chr17_42044494_-SINEAluName=AluSp
ADediting_621388chr17_42044504_-SINEAluName=AluSp
ADediting_621389chr17_42044575_-SINEAluName=AluSp
ADediting_621390chr17_42044577_-SINEAluName=AluSp
ADediting_621391chr17_42044985_-SINEAluName=AluYi6
ADediting_621392chr17_42044986_-SINEAluName=AluYi6
ADediting_621393chr17_42045014_-SINEAluName=AluYi6
ADediting_621394chr17_42045050_-SINEAluName=AluYi6
ADediting_621395chr17_42045056_-SINEAluName=AluYi6
ADediting_621396chr17_42045082_-SINEAluName=AluYi6
ADediting_621397chr17_42045189_-SINEAluName=AluYi6
ADediting_621398chr17_42045190_-SINEAluName=AluYi6
ADediting_621399chr17_42045198_-SINEAluName=AluYi6
ADediting_621400chr17_42045280_-SINEAluName=AluYg6
ADediting_621401chr17_42045323_-SINEAluName=AluYg6
ADediting_621402chr17_42045324_-SINEAluName=AluYg6
ADediting_621403chr17_42046334_-SINEAluName=AluJr
ADediting_621404chr17_42046336_-SINEAluName=AluJr
ADediting_621405chr17_42046341_-SINEAluName=AluJr
ADediting_621406chr17_42046348_-SINEAluName=AluJr
ADediting_621407chr17_42046349_-SINEAluName=AluJr
ADediting_621408chr17_42046350_-SINEAluName=AluJr
ADediting_621409chr17_42046363_-SINEAluName=AluJr
ADediting_621410chr17_42046373_-SINEAluName=AluJr
ADediting_621411chr17_42046420_-SINEAluName=AluJr
ADediting_621412chr17_42046465_-SINEAluName=AluJr
ADediting_621413chr17_42046468_-SINEAluName=AluJr
ADediting_621414chr17_42046476_-SINEAluName=AluJr
ADediting_621415chr17_42046478_-SINEAluName=AluJr
ADediting_621416chr17_42046488_-SINEAluName=AluJr
ADediting_621417chr17_42046500_-SINEAluName=AluJr
ADediting_621418chr17_42046505_-SINEAluName=AluJr
ADediting_621419chr17_42046517_-SINEAluName=AluJr
ADediting_621420chr17_42046531_-SINEAluName=AluJr
ADediting_621421chr17_42046548_-SINEAluName=AluJr
ADediting_621422chr17_42046930_-SINEAluName=AluSx
ADediting_621423chr17_42046978_-SINEAluName=AluSx
ADediting_621424chr17_42046991_-SINEAluName=AluSx
ADediting_621425chr17_42047000_-SINEAluName=AluSx
ADediting_621426chr17_42047001_-SINEAluName=AluSx
ADediting_621427chr17_42047011_-SINEAluName=AluSx
ADediting_621428chr17_42047027_-SINEAluName=AluSx
ADediting_621429chr17_42047038_-SINEAluName=AluY
ADediting_621430chr17_42047128_-SINEAluName=AluY
ADediting_621431chr17_42047143_-SINEAluName=AluY
ADediting_621432chr17_42047160_-SINEAluName=AluY
ADediting_621433chr17_42047237_-SINEAluName=AluY
ADediting_621434chr17_42047304_-SINEAluName=AluY
ADediting_621435chr17_42047305_-SINEAluName=AluY
ADediting_621436chr17_42047337_-SINEAluName=AluSx
ADediting_621437chr17_42047442_-SINEAluName=AluSx
ADediting_621438chr17_42047447_-SINEAluName=AluSx
ADediting_621439chr17_42047448_-SINEAluName=AluSx
ADediting_621440chr17_42047683_-SINEAluName=AluSx3
ADediting_621441chr17_42047689_-SINEAluName=AluSx3
ADediting_621442chr17_42047708_-SINEAluName=AluSx3
ADediting_621443chr17_42047746_-SINEAluName=AluSx3
ADediting_621444chr17_42047750_-SINEAluName=AluSx3
ADediting_621445chr17_42047765_-SINEAluName=AluSx3
ADediting_621446chr17_42047778_-SINEAluName=AluSx3
ADediting_621447chr17_42047791_-SINEAluName=AluSx3
ADediting_621448chr17_42047818_-SINEAluName=AluSx3
ADediting_621449chr17_42047920_-SINEAluName=AluSx3
ADediting_621450chr17_42047925_-SINEAluName=AluSx3
ADediting_621451chr17_42047926_-SINEAluName=AluSx3
ADediting_621452chr17_42047928_-SINEAluName=AluSx3
ADediting_621453chr17_42048281_-SINEAluName=AluJo
ADediting_621454chr17_42048287_-SINEAluName=AluJo
ADediting_621455chr17_42048304_-SINEAluName=AluJo
ADediting_621456chr17_42048321_-SINEAluName=AluJo
ADediting_621457chr17_42048322_-SINEAluName=AluJo
ADediting_621458chr17_42048336_-SINEAluName=AluJo
ADediting_621459chr17_42048356_-SINEAluName=AluJo
ADediting_621460chr17_42048367_-SINEAluName=AluJo
ADediting_621461chr17_42048371_-SINEAluName=AluJo
ADediting_621462chr17_42048372_-SINEAluName=AluJo
ADediting_621463chr17_42048373_-SINEAluName=AluJo
ADediting_621464chr17_42048433_-SINEAluName=AluJo
ADediting_621465chr17_42048445_-SINEAluName=AluJo
ADediting_621466chr17_42048462_-SINEAluName=AluJo
ADediting_621467chr17_42048463_-SINEAluName=AluJo
ADediting_621468chr17_42048491_-SINEAluName=AluJo
ADediting_621469chr17_42048507_-SINEAluName=AluJo
ADediting_621470chr17_42048525_-SINEAluName=AluJo
ADediting_621471chr17_42048541_-SINEAluName=AluJo
ADediting_1546480chr17_42038988_-SINEAluName=AluSx1
ADediting_1546481chr17_42044059_-SINEAluName=AluJb
ADediting_1546482chr17_42044114_-SINEAluName=AluJb
ADediting_1546483chr17_42044199_-SINEAluName=AluJb
ADediting_1546484chr17_42045151_-SINEAluName=AluYi6
ADediting_1546485chr17_42045246_-SINEAluName=AluYg6
ADediting_1546486chr17_42046376_-SINEAluName=AluJr
ADediting_1546487chr17_42046426_-SINEAluName=AluJr
ADediting_1546488chr17_42046689_-SINEAluName=FLAM_C
ADediting_1546489chr17_42046915_-SINEAluName=AluSx
ADediting_1546490chr17_42047037_-SINEAluName=AluY
ADediting_1546491chr17_42048309_-SINEAluName=AluJo
ADediting_1546492chr17_42048410_-SINEAluName=AluJo
ADediting_1546493chr17_42048421_-SINEAluName=AluJo
ADediting_1546494chr17_42048423_-SINEAluName=AluJo
ADediting_1546495chr17_42048501_-SINEAluName=AluJo
ADediting_1546496chr17_42048547_-SINEAluName=AluJo
ADediting_1546497chr17_42049919_-DNAhAT-CharlieName=MER3
ADediting_1546498chr17_42054790_-SINEAluName=AluSx1
ADediting_1546499chr17_42056532_-SINEAluName=AluJr
ADediting_1546500chr17_42056540_-SINEAluName=AluJr
ADediting_1546501chr17_42056544_-SINEAluName=AluJr
ADediting_1546502chr17_42057004_-SINEAluName=AluJr
ADediting_1546503chr17_42057079_-SINEAluName=AluJr
ADediting_1546504chr17_42057128_-SINEAluName=AluJr
ADediting_1546505chr17_42057131_-SINEAluName=AluJr
ADediting_1546506chr17_42057137_-SINEAluName=AluJr
ADediting_1546507chr17_42059279_-LINEL2Name=L2b
ADediting_1546508chr17_42059854_-SINEAluName=AluSz
ADediting_1546509chr17_42059868_-SINEAluName=AluSz
ADediting_1546510chr17_42061359_-SINEAluName=AluSz6
ADediting_1546511chr17_42061365_-SINEAluName=AluSz6

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RNA A-to-I editing events in the alternative splicing sites for ZNF385C

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZNF385C

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Soverview
Soverview
Soverview
Soverview
ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for ZNF385C

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for ZNF385C


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000187595.16ENST00000461831.1ZNF385C-203hsa-miR-589-3pchr1742026299420263068mer-1a4202629942026321168-29.16
ADediting_1337757chr7_5495852_-ENSG00000187595.16ENST00000618554.4ZNF385C-205hsa-miR-589-3pchr1742026299420263068mer-1a4202629942026321168-29.16
ADediting_1337757chr7_5495852_-ENSG00000187595.16ENST00000649819.1ZNF385C-206hsa-miR-589-3pchr1742026299420263068mer-1a4202629942026321168-29.16
ADediting_1535954chr14_101045974_+ENSG00000187595.16ENST00000461831.1ZNF385C-203hsa-miR-381-3pchr1742025707420257137mer-m84202570642025727160-17
ADediting_1535954chr14_101045974_+ENSG00000187595.16ENST00000618554.4ZNF385C-205hsa-miR-381-3pchr1742025707420257137mer-m84202570642025727160-17
ADediting_1535954chr14_101045974_+ENSG00000187595.16ENST00000649819.1ZNF385C-206hsa-miR-381-3pchr1742025707420257137mer-m84202570642025727160-17

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000187595.16ENST00000461831.1ZNF385C-203hsa-miR-589-3pchr1742026266420262727mer-m84202626542026287147-17.77
ADediting_1337757chr7_5495852_-ENSG00000187595.16ENST00000618554.4ZNF385C-205hsa-miR-589-3pchr1742026266420262727mer-m84202626542026287147-17.77
ADediting_1337757chr7_5495852_-ENSG00000187595.16ENST00000649819.1ZNF385C-206hsa-miR-589-3pchr1742026266420262727mer-m84202626542026287147-17.77

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ZNF385C

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for ZNF385C

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_1546497chr17_42049919_-0.0001456606031325550.3052523693894590.01785501840464210.1931868711428540.352305630985820.0764729531215255
DLPFCADediting_621379chr17_42044232_-0.01323284886187610.1405776470377270.2188575188113020.07003212264877857.22317300314805e-110.359114019022914
DLPFCADediting_621380chr17_42044258_-0.004758469720493680.1599451938120230.06058090988395850.1067070000019851.53512309563057e-090.334502839940875
DLPFCADediting_621381chr17_42044274_-0.001171658445128440.1835162009280230.05596271620234550.1086733223826485.03236828059942e-090.324328122780723
DLPFCADediting_621382chr17_42044289_-0.0007458684990983350.1905367981323330.611025727534650.02899816781309867.32499402050482e-190.475116115535638
DLPFCADediting_621388chr17_42044504_-0.1641044384107150.07922194038664360.771109943989177-0.01658921511858897.94714714288199e-180.462374779266056
DLPFCADediting_621396chr17_42045082_-0.249147371006930.06564779113108740.406589509405686-0.04730043033543173.10447743751041e-180.467461914598723
CERADediting_621403chr17_42046334_-0.0119170361605130.2048471070566330.0001337714651383440.3068624360203080.03608662415039520.171299561810136
CERADediting_621404chr17_42046336_-0.0001725274329618930.3020235517142682.23872030981963e-060.3751844540751360.6145288840789780.041449413146764
DLPFCADediting_621405chr17_42046341_-0.08645344315486510.09753368169498430.926819966386678-0.005237656056405986.57608283245627e-080.300909873550426
CERADediting_621415chr17_42046478_-0.001237379710823190.261325907845384.94647846945071e-050.3250229001138190.0160695960942830.196283752581077
DLPFCADediting_621418chr17_42046505_-0.5081976880041560.03771800299850270.162451461311275-0.07953267864252565.60067133681947e-190.476517811656959
DLPFCADediting_621425chr17_42047000_-0.1490347764803320.08214729339595010.917473720578916-0.005908838690197615.63226771846256e-140.409672998447192
DLPFCADediting_621427chr17_42047011_-0.1988625929270220.07316940907222860.737748318955269-0.01909284001239342.48215269230012e-130.399882045901052
DLPFCADediting_621431chr17_42047143_-0.778857337313462-0.01601251117137360.0453776343535835-0.1137473196197981.0782811693514e-100.356006734014159
DLPFCADediting_621438chr17_42047447_-0.2216840270751960.06960545870950620.852919296787793-0.01057213818816081.31749381217924e-080.315794708206618
DLPFCADediting_621446chr17_42047778_-0.1924658099151330.07422125529834970.637039234683735-0.02690268058588935.3054435768265e-170.451833817524281
DLPFCADediting_621451chr17_42047926_-0.0829260802449060.09864020197564660.3025286071401420.05874507478045572.20592799309983e-080.311112078721193
DLPFCADediting_621452chr17_42047928_-0.01302329133707690.1408973643640820.09420423202418950.095224107902611.56161505788694e-100.353104167715384
DLPFCADediting_621465chr17_42048445_-0.02203887588300160.1300188192710650.5776328391377620.03174698886571567.99799968528978e-110.358326949976702
DLPFCADediting_621466chr17_42048462_-0.01670053698117430.135844728909260.4252620263238050.04544523021169231.57601193630858e-100.353031868811503
DLPFCADediting_621468chr17_42048491_-0.002023251635723910.174674224532470.1198671823726720.08852099119303041.74553728576538e-100.352225744399963
DLPFCADediting_621469chr17_42048507_-0.008743715577041230.1486868038281670.2717165811550350.06261739074760964.5706498825233e-130.395756444495612

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC2.56514011120909e-180.4684844320821361.4838640285772e-270.5651206319055470.001325864486912470.181549880483093
AC5.99349577135091e-360.6848413738829212.29896124145895e-270.6146414777805281.06111818339953e-160.492786073654571
PCC1.7984770272173e-190.5923016737206355.53550836260099e-160.5421008623986832.10362618289435e-080.391691084721312
CER1.58707572724976e-100.4921803820761833.64959754753903e-080.4310888829457950.01298279657849080.202426345249125
FP0.009215945392169680.1946740109082510.06049533110363920.1409892219595342.18955846124879e-060.34630568982448
IFG0.0408976165380090.4116554547600840.0550678106650550.3883370579675270.07775284041249970.359281423328892
STG0.3529913289297530.1026103601613990.54381805115868-0.06716607902978113.75877044695178e-060.480366156078966

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Relation with AD stages for ZNF385C

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.

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RelatedDrugs for ZNF385C

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ZNF385C

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource