ADeditome: functional annotation of RNA A-to-I editing in AD

Gene summary for PGAM5

Gene summary

Gene information	Gene symbol	PGAM5
	Gene ID	192111
	Gene name	PGAM family member 5, mitochondrial serine/threonine protein phosphatase
	Synonyms	BXLBV68
	Cytomap	12q24.33
	Type of gene	protein-coding
	Description	serine/threonine-protein phosphatase PGAM5, mitochondrialBcl-XL-binding protein v68PGAM family member 5, serine/threonine protein phosphatase, mitochondrialphosphoglycerate mutase family member 5
	Modification date	20200313
	UniProtAcc	Q96HS1,
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for PGAM5

RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA editing frequencies across three data sets.

The number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA A-to-I editing events in AD.

ADediting_330649(132711519, +), ADediting_330650(132711600, +), ADediting_330651(132712513, +), ADediting_330652(132712521, +), ADediting_330653(132712557, +), ADediting_330654(132712560, +), ADediting_330655(132712561, +), ADediting_330656(132712636, +), ADediting_330657(132712656, +), ADediting_330658(132712896, +), ADediting_330659(132712902, +), ADediting_330660(132713085, +), ADediting_330661(132713150, +), ADediting_330662(132715695, +), ADediting_330663(132715854, +), ADediting_330664(132716185, +), ADediting_330665(132716186, +), ADediting_330666(132716284, +), ADediting_330667(132716292, +), ADediting_330668(132716346, +), ADediting_330669(132716347, +), ADediting_330670(132716350, +), ADediting_330671(132716359, +), ADediting_330672(132716491, +), ADediting_330673(132716497, +), ADediting_330674(132721316, +), ADediting_330675(132721318, +), ADediting_330676(132721328, +), ADediting_330677(132721340, +), ADediting_330678(132721344, +), ADediting_330679(132721348, +), ADediting_330680(132721356, +), ADediting_330681(132721370, +), ADediting_330682(132721375, +), ADediting_330683(132721380, +), ADediting_330684(132721388, +), ADediting_330685(132721430, +), ADediting_330686(132721433, +), ADediting_330687(132721434, +), ADediting_330688(132721435, +), ADediting_330689(132721436, +), ADediting_330690(132721437, +), ADediting_330691(132721439, +), ADediting_330692(132721441, +), ADediting_330693(132721448, +), ADediting_330694(132721467, +), ADediting_330695(132721471, +), ADediting_330696(132721473, +), ADediting_330697(132721483, +), ADediting_330698(132721490, +), ADediting_330699(132721496, +), ADediting_330700(132721509, +), ADediting_330701(132721522, +), ADediting_330702(132721535, +), ADediting_330703(132721539, +), ADediting_330704(132721546, +), ADediting_330705(132721559, +), ADediting_330706(132721653, +), ADediting_330707(132721663, +), ADediting_330708(132721668, +), ADediting_330709(132721669, +), ADediting_330710(132721689, +), ADediting_330711(132721693, +), ADediting_330712(132721706, +), ADediting_330713(132721717, +), ADediting_330714(132721729, +), ADediting_330715(132721753, +), ADediting_330716(132721754, +), ADediting_330717(132721763, +), ADediting_330718(132721769, +), ADediting_330719(132721773, +), ADediting_330720(132721824, +), ADediting_330721(132721825, +), ADediting_330722(132721831, +), ADediting_330723(132721837, +), ADediting_330724(132721842, +), ADediting_330725(132721865, +), ADediting_330726(132721877, +), ADediting_330727(132721878, +), ADediting_330728(132721879, +), ADediting_330729(132722331, +), ADediting_330730(132722350, +), ADediting_330731(132722351, +), ADediting_330732(132722352, +), ADediting_330733(132722368, +), ADediting_330734(132722376, +), ADediting_330735(132722377, +), ADediting_330736(132722380, +), ADediting_330737(132722392, +), ADediting_330738(132722416, +), ADediting_330739(132722417, +), ADediting_330740(132722424, +), ADediting_330741(132722430, +), ADediting_330742(132722433, +), ADediting_330743(132722447, +), ADediting_330744(132722472, +), ADediting_1531718(132711671, +), ADediting_1531719(132721389, +), ADediting_1531720(132721554, +), ADediting_1531721(132721632, +), ADediting_1612693(132721334, +), ADediting_1612694(132721479, +), ADediting_1612695(132721745, +),

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RNA editing positional annotations for PGAM5 using Annovar

Protein coding RNA editing(s).

ADeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

ADeditome ID	Position	Variant type
ADediting_330649	chr12_132711519_+	ncRNA_intronic
ADediting_330650	chr12_132711600_+	ncRNA_intronic
ADediting_330651	chr12_132712513_+	ncRNA_intronic
ADediting_330652	chr12_132712521_+	ncRNA_intronic
ADediting_330653	chr12_132712557_+	ncRNA_intronic
ADediting_330654	chr12_132712560_+	ncRNA_intronic
ADediting_330655	chr12_132712561_+	ncRNA_intronic
ADediting_330656	chr12_132712636_+	ncRNA_intronic
ADediting_330657	chr12_132712656_+	ncRNA_intronic
ADediting_330658	chr12_132712896_+	ncRNA_intronic
ADediting_330659	chr12_132712902_+	ncRNA_intronic
ADediting_330660	chr12_132713085_+	ncRNA_intronic
ADediting_330661	chr12_132713150_+	ncRNA_intronic
ADediting_330662	chr12_132715695_+	intronic
ADediting_330663	chr12_132715854_+	intronic
ADediting_330664	chr12_132716185_+	intronic
ADediting_330665	chr12_132716186_+	intronic
ADediting_330666	chr12_132716284_+	intronic
ADediting_330667	chr12_132716292_+	intronic
ADediting_330668	chr12_132716346_+	intronic
ADediting_330669	chr12_132716347_+	intronic
ADediting_330670	chr12_132716350_+	intronic
ADediting_330671	chr12_132716359_+	intronic
ADediting_330672	chr12_132716491_+	intronic
ADediting_330673	chr12_132716497_+	intronic
ADediting_330674	chr12_132721316_+	UTR3
ADediting_330675	chr12_132721318_+	UTR3
ADediting_330676	chr12_132721328_+	UTR3
ADediting_330677	chr12_132721340_+	UTR3
ADediting_330678	chr12_132721344_+	UTR3
ADediting_330679	chr12_132721348_+	UTR3
ADediting_330680	chr12_132721356_+	UTR3
ADediting_330681	chr12_132721370_+	UTR3
ADediting_330682	chr12_132721375_+	UTR3
ADediting_330683	chr12_132721380_+	UTR3
ADediting_330684	chr12_132721388_+	UTR3
ADediting_330685	chr12_132721430_+	UTR3
ADediting_330686	chr12_132721433_+	UTR3
ADediting_330687	chr12_132721434_+	UTR3
ADediting_330688	chr12_132721435_+	UTR3
ADediting_330689	chr12_132721436_+	UTR3
ADediting_330690	chr12_132721437_+	UTR3
ADediting_330691	chr12_132721439_+	UTR3
ADediting_330692	chr12_132721441_+	UTR3
ADediting_330693	chr12_132721448_+	UTR3
ADediting_330694	chr12_132721467_+	UTR3
ADediting_330695	chr12_132721471_+	UTR3
ADediting_330696	chr12_132721473_+	UTR3
ADediting_330697	chr12_132721483_+	UTR3
ADediting_330698	chr12_132721490_+	UTR3
ADediting_330699	chr12_132721496_+	UTR3
ADediting_330700	chr12_132721509_+	UTR3
ADediting_330701	chr12_132721522_+	UTR3
ADediting_330702	chr12_132721535_+	UTR3
ADediting_330703	chr12_132721539_+	UTR3
ADediting_330704	chr12_132721546_+	UTR3
ADediting_330705	chr12_132721559_+	UTR3
ADediting_330706	chr12_132721653_+	UTR3
ADediting_330707	chr12_132721663_+	UTR3
ADediting_330708	chr12_132721668_+	UTR3
ADediting_330709	chr12_132721669_+	UTR3
ADediting_330710	chr12_132721689_+	UTR3
ADediting_330711	chr12_132721693_+	UTR3
ADediting_330712	chr12_132721706_+	UTR3
ADediting_330713	chr12_132721717_+	UTR3
ADediting_330714	chr12_132721729_+	UTR3
ADediting_330715	chr12_132721753_+	UTR3
ADediting_330716	chr12_132721754_+	UTR3
ADediting_330717	chr12_132721763_+	UTR3
ADediting_330718	chr12_132721769_+	UTR3
ADediting_330719	chr12_132721773_+	UTR3
ADediting_330720	chr12_132721824_+	UTR3
ADediting_330721	chr12_132721825_+	UTR3
ADediting_330722	chr12_132721831_+	UTR3
ADediting_330723	chr12_132721837_+	UTR3
ADediting_330724	chr12_132721842_+	UTR3
ADediting_330725	chr12_132721865_+	UTR3
ADediting_330726	chr12_132721877_+	UTR3
ADediting_330727	chr12_132721878_+	UTR3
ADediting_330728	chr12_132721879_+	UTR3
ADediting_330729	chr12_132722331_+	UTR3
ADediting_330730	chr12_132722350_+	UTR3
ADediting_330731	chr12_132722351_+	UTR3
ADediting_330732	chr12_132722352_+	UTR3
ADediting_330733	chr12_132722368_+	UTR3
ADediting_330734	chr12_132722376_+	UTR3
ADediting_330735	chr12_132722377_+	UTR3
ADediting_330736	chr12_132722380_+	UTR3
ADediting_330737	chr12_132722392_+	UTR3
ADediting_330738	chr12_132722416_+	UTR3
ADediting_330739	chr12_132722417_+	UTR3
ADediting_330740	chr12_132722424_+	UTR3
ADediting_330741	chr12_132722430_+	UTR3
ADediting_330742	chr12_132722433_+	UTR3
ADediting_330743	chr12_132722447_+	UTR3
ADediting_330744	chr12_132722472_+	UTR3
ADediting_1531718	chr12_132711671_+	ncRNA_intronic
ADediting_1531719	chr12_132721389_+	UTR3
ADediting_1531720	chr12_132721554_+	UTR3
ADediting_1531721	chr12_132721632_+	UTR3
ADediting_1612693	chr12_132721334_+	UTR3
ADediting_1612694	chr12_132721479_+	UTR3
ADediting_1612695	chr12_132721745_+	UTR3

Repat-regional RNA editing(s).

ADeditome ID	Position	Repeat family	Repeat sub family	Repeat name
ADediting_330649	chr12_132711519_+	SINE	Alu	Name=AluJo
ADediting_330650	chr12_132711600_+	SINE	Alu	Name=AluJo
ADediting_330651	chr12_132712513_+	SINE	Alu	Name=AluSp
ADediting_330652	chr12_132712521_+	SINE	Alu	Name=AluSp
ADediting_330653	chr12_132712557_+	SINE	Alu	Name=AluSp
ADediting_330654	chr12_132712560_+	SINE	Alu	Name=AluSp
ADediting_330655	chr12_132712561_+	SINE	Alu	Name=AluSp
ADediting_330656	chr12_132712636_+	SINE	Alu	Name=AluSp
ADediting_330657	chr12_132712656_+	SINE	Alu	Name=AluSp
ADediting_330658	chr12_132712896_+	SINE	Alu	Name=AluSz
ADediting_330659	chr12_132712902_+	SINE	Alu	Name=AluSz
ADediting_330660	chr12_132713085_+	SINE	Alu	Name=AluSz
ADediting_330661	chr12_132713150_+	SINE	Alu	Name=AluSz
ADediting_330662	chr12_132715695_+	SINE	Alu	Name=AluSx1
ADediting_330663	chr12_132715854_+	SINE	Alu	Name=AluSx1
ADediting_330664	chr12_132716185_+	SINE	Alu	Name=AluSc8
ADediting_330665	chr12_132716186_+	SINE	Alu	Name=AluSc8
ADediting_330666	chr12_132716284_+	SINE	Alu	Name=AluSc8
ADediting_330667	chr12_132716292_+	SINE	Alu	Name=AluSc8
ADediting_330668	chr12_132716346_+	SINE	Alu	Name=AluSc8
ADediting_330669	chr12_132716347_+	SINE	Alu	Name=AluSc8
ADediting_330670	chr12_132716350_+	SINE	Alu	Name=AluSc8
ADediting_330671	chr12_132716359_+	SINE	Alu	Name=AluSc8
ADediting_330672	chr12_132716491_+	SINE	Alu	Name=AluSx4
ADediting_330673	chr12_132716497_+	SINE	Alu	Name=AluSx4
ADediting_330674	chr12_132721316_+	SINE	Alu	Name=AluJo
ADediting_330675	chr12_132721318_+	SINE	Alu	Name=AluJo
ADediting_330676	chr12_132721328_+	SINE	Alu	Name=AluJo
ADediting_330677	chr12_132721340_+	SINE	Alu	Name=AluJo
ADediting_330678	chr12_132721344_+	SINE	Alu	Name=AluJo
ADediting_330679	chr12_132721348_+	SINE	Alu	Name=AluJo
ADediting_330680	chr12_132721356_+	SINE	Alu	Name=AluJo
ADediting_330681	chr12_132721370_+	SINE	Alu	Name=AluJo
ADediting_330682	chr12_132721375_+	SINE	Alu	Name=AluJo
ADediting_330683	chr12_132721380_+	SINE	Alu	Name=AluJo
ADediting_330684	chr12_132721388_+	SINE	Alu	Name=AluJo
ADediting_330685	chr12_132721430_+	SINE	Alu	Name=AluJo
ADediting_330686	chr12_132721433_+	SINE	Alu	Name=AluJo
ADediting_330687	chr12_132721434_+	SINE	Alu	Name=AluJo
ADediting_330688	chr12_132721435_+	SINE	Alu	Name=AluJo
ADediting_330689	chr12_132721436_+	SINE	Alu	Name=AluJo
ADediting_330690	chr12_132721437_+	SINE	Alu	Name=AluJo
ADediting_330691	chr12_132721439_+	SINE	Alu	Name=AluJo
ADediting_330692	chr12_132721441_+	SINE	Alu	Name=AluJo
ADediting_330693	chr12_132721448_+	SINE	Alu	Name=AluJo
ADediting_330694	chr12_132721467_+	SINE	Alu	Name=AluJo
ADediting_330695	chr12_132721471_+	SINE	Alu	Name=AluJo
ADediting_330696	chr12_132721473_+	SINE	Alu	Name=AluJo
ADediting_330697	chr12_132721483_+	SINE	Alu	Name=AluJo
ADediting_330698	chr12_132721490_+	SINE	Alu	Name=AluJo
ADediting_330699	chr12_132721496_+	SINE	Alu	Name=AluJo
ADediting_330700	chr12_132721509_+	SINE	Alu	Name=AluJo
ADediting_330701	chr12_132721522_+	SINE	Alu	Name=AluJo
ADediting_330702	chr12_132721535_+	SINE	Alu	Name=AluJo
ADediting_330703	chr12_132721539_+	SINE	Alu	Name=AluJo
ADediting_330704	chr12_132721546_+	SINE	Alu	Name=AluJo
ADediting_330705	chr12_132721559_+	SINE	Alu	Name=AluJo
ADediting_330706	chr12_132721653_+	SINE	Alu	Name=AluSq
ADediting_330707	chr12_132721663_+	SINE	Alu	Name=AluSq
ADediting_330708	chr12_132721668_+	SINE	Alu	Name=AluSq
ADediting_330709	chr12_132721669_+	SINE	Alu	Name=AluSq
ADediting_330710	chr12_132721689_+	SINE	Alu	Name=AluSq
ADediting_330711	chr12_132721693_+	SINE	Alu	Name=AluSq
ADediting_330712	chr12_132721706_+	SINE	Alu	Name=AluSq
ADediting_330713	chr12_132721717_+	SINE	Alu	Name=AluSq
ADediting_330714	chr12_132721729_+	SINE	Alu	Name=AluSq
ADediting_330715	chr12_132721753_+	SINE	Alu	Name=AluSq
ADediting_330716	chr12_132721754_+	SINE	Alu	Name=AluSq
ADediting_330717	chr12_132721763_+	SINE	Alu	Name=AluSq
ADediting_330718	chr12_132721769_+	SINE	Alu	Name=AluSq
ADediting_330719	chr12_132721773_+	SINE	Alu	Name=AluSq
ADediting_330720	chr12_132721824_+	SINE	Alu	Name=AluSq
ADediting_330721	chr12_132721825_+	SINE	Alu	Name=AluSq
ADediting_330722	chr12_132721831_+	SINE	Alu	Name=AluSq
ADediting_330723	chr12_132721837_+	SINE	Alu	Name=AluSq
ADediting_330724	chr12_132721842_+	SINE	Alu	Name=AluSq
ADediting_330725	chr12_132721865_+	SINE	Alu	Name=AluSq
ADediting_330726	chr12_132721877_+	SINE	Alu	Name=AluSq
ADediting_330727	chr12_132721878_+	SINE	Alu	Name=AluSq
ADediting_330728	chr12_132721879_+	SINE	Alu	Name=AluSq
ADediting_330729	chr12_132722331_+	SINE	Alu	Name=AluSg
ADediting_330730	chr12_132722350_+	SINE	Alu	Name=AluSg
ADediting_330731	chr12_132722351_+	SINE	Alu	Name=AluSg
ADediting_330732	chr12_132722352_+	SINE	Alu	Name=AluSg
ADediting_330733	chr12_132722368_+	SINE	Alu	Name=AluSg
ADediting_330734	chr12_132722376_+	SINE	Alu	Name=AluSg
ADediting_330735	chr12_132722377_+	SINE	Alu	Name=AluSg
ADediting_330736	chr12_132722380_+	SINE	Alu	Name=AluSg
ADediting_330737	chr12_132722392_+	SINE	Alu	Name=AluSg
ADediting_330738	chr12_132722416_+	SINE	Alu	Name=AluSg
ADediting_330739	chr12_132722417_+	SINE	Alu	Name=AluSg
ADediting_330740	chr12_132722424_+	SINE	Alu	Name=AluSg
ADediting_330741	chr12_132722430_+	SINE	Alu	Name=AluSg
ADediting_330742	chr12_132722433_+	SINE	Alu	Name=AluSg
ADediting_330743	chr12_132722447_+	SINE	Alu	Name=AluSg
ADediting_330744	chr12_132722472_+	SINE	Alu	Name=AluSg
ADediting_1531718	chr12_132711671_+	SINE	Alu	Name=AluJo
ADediting_1531719	chr12_132721389_+	SINE	Alu	Name=AluJo
ADediting_1531720	chr12_132721554_+	SINE	Alu	Name=AluJo
ADediting_1531721	chr12_132721632_+	SINE	Alu	Name=AluSq
ADediting_1612693	chr12_132721334_+	SINE	Alu	Name=AluJo
ADediting_1612694	chr12_132721479_+	SINE	Alu	Name=AluJo
ADediting_1612695	chr12_132721745_+	SINE	Alu	Name=AluSq

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RNA A-to-I editing events in the alternative splicing sites for PGAM5

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

ADeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PGAM5

Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

- Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

ADeditome ID

Chr

Positoing

Skipped exon

ENSG

ENSTs

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Protein coding region RNA A-to-I editings for PGAM5

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for PGAM5

RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

ADeditom_ID	Position	ENSG	ENST	Transcript name	miRNA ID	Chromosome	Targt	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
ADediting_1531719	chr12_132721389_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-12113	chr12	132721382	132721388	7mer-m8	132721369	132721389	149	-19.67
ADediting_1531719	chr12_132721389_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4539	chr12	132721382	132721388	7mer-m8	132721370	132721389	159	-22.01
ADediting_1531721	chr12_132721632_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3940-3p	chr12	132721629	132721635	7mer-m8	132721615	132721636	143	-21.15
ADediting_1612693	chr12_132721334_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6768-5p	chr12	132721328	132721334	7mer-m8	132721313	132721335	140	-23.35
ADediting_1612695	chr12_132721745_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3622b-5p	chr12	132721740	132721746	7mer-m8	132721729	132721747	143	-25.8
ADediting_1612695	chr12_132721745_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4645-5p	chr12	132721743	132721749	7mer-m8	132721732	132721750	142	-13.03
ADediting_1612695	chr12_132721745_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4673	chr12	132721743	132721749	7mer-m8	132721725	132721750	150	-22.99
ADediting_330678	chr12_132721344_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-1207-3p	chr12	132721337	132721343	7mer-m8	132721327	132721344	140	-12.56
ADediting_330678	chr12_132721344_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-646	chr12	132721339	132721345	7mer-m8	132721328	132721346	145	-14.99
ADediting_330680	chr12_132721356_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4707-5p	chr12	132721352	132721358	7mer-m8	132721337	132721359	140	-28
ADediting_330685	chr12_132721430_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-374b-3p	chr12	132721427	132721434	8mer-1a	132721413	132721434	141	-8.74
ADediting_330686	chr12_132721433_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-222-5p	chr12	132721427	132721434	8mer-1a	132721411	132721434	146	-15.3
ADediting_330686	chr12_132721433_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-30a-3p	chr12	132721429	132721436	8mer-1a	132721414	132721436	145	-10.42
ADediting_330686	chr12_132721433_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-30d-3p	chr12	132721429	132721436	8mer-1a	132721410	132721436	149	-17.26
ADediting_330686	chr12_132721433_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-30e-3p	chr12	132721429	132721436	8mer-1a	132721414	132721436	145	-11.19
ADediting_330687	chr12_132721434_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-325	chr12	132721427	132721434	8mer-1a	132721412	132721434	141	-14.36
ADediting_330688	chr12_132721435_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-630	chr12	132721433	132721440	8mer-1a	132721419	132721440	157	-16.15
ADediting_330691	chr12_132721439_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-153-5p	chr12	132721432	132721438	7mer-m8	132721419	132721439	146	-9.95
ADediting_330691	chr12_132721439_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-20a-3p	chr12	132721435	132721442	8mer-1a	132721421	132721442	151	-10.59
ADediting_330693	chr12_132721448_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4480	chr12	132721443	132721449	7mer-m8	132721430	132721450	140	-12.86
ADediting_330694	chr12_132721467_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6786-3p	chr12	132721462	132721468	7mer-m8	132721446	132721469	148	-20.84
ADediting_330695	chr12_132721471_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-508-5p	chr12	132721468	132721474	7mer-m8	132721452	132721475	156	-21.49
ADediting_330696	chr12_132721473_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3649	chr12	132721472	132721478	7mer-1a	132721459	132721478	144	-21.57
ADediting_330697	chr12_132721483_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-1207-3p	chr12	132721476	132721482	7mer-m8	132721466	132721483	149	-16.89
ADediting_330697	chr12_132721483_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-646	chr12	132721478	132721484	7mer-m8	132721465	132721485	150	-21.69
ADediting_330698	chr12_132721490_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3943	chr12	132721487	132721493	7mer-m8	132721474	132721494	146	-22.28
ADediting_330699	chr12_132721496_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6849-3p	chr12	132721489	132721495	7mer-m8	132721475	132721496	140	-18.03
ADediting_330701	chr12_132721522_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3943	chr12	132721518	132721524	7mer-m8	132721504	132721525	159	-26.59
ADediting_330701	chr12_132721522_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6840-5p	chr12	132721516	132721522	7mer-m8	132721499	132721523	156	-28.8
ADediting_330703	chr12_132721539_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-324-3p	chr12	132721532	132721538	7mer-m8	132721513	132721539	149	-30.82
ADediting_330703	chr12_132721539_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4690-3p	chr12	132721536	132721542	7mer-m8	132721524	132721543	169	-31.41
ADediting_330703	chr12_132721539_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-5685	chr12	132721536	132721542	7mer-m8	132721520	132721543	157	-26.81
ADediting_330703	chr12_132721539_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6856-3p	chr12	132721537	132721543	7mer-m8	132721522	132721544	154	-28.26
ADediting_330704	chr12_132721546_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-140-3p	chr12	132721540	132721546	7mer-m8	132721527	132721547	140	-16.14
ADediting_330707	chr12_132721663_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4285	chr12	132721659	132721665	7mer-m8	132721650	132721666	151	-24.79
ADediting_330709	chr12_132721669_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-485-5p	chr12	132721666	132721672	7mer-m8	132721653	132721673	153	-20.87
ADediting_330709	chr12_132721669_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-604	chr12	132721664	132721670	7mer-m8	132721653	132721671	145	-21.23
ADediting_330709	chr12_132721669_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6884-5p	chr12	132721666	132721672	7mer-m8	132721650	132721673	147	-28.25
ADediting_330710	chr12_132721689_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3622a-3p	chr12	132721685	132721692	8mer-1a	132721671	132721692	148	-20.48
ADediting_330710	chr12_132721689_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3622b-3p	chr12	132721685	132721692	8mer-1a	132721672	132721692	155	-22.19
ADediting_330711	chr12_132721693_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-1255b-2-3p	chr12	132721687	132721693	7mer-m8	132721673	132721694	140	-13.19
ADediting_330711	chr12_132721693_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-589-5p	chr12	132721691	132721697	7mer-m8	132721677	132721698	160	-19.85
ADediting_330712	chr12_132721706_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4537	chr12	132721703	132721709	7mer-m8	132721687	132721710	147	-19.88
ADediting_330713	chr12_132721717_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4691-3p	chr12	132721714	132721720	7mer-m8	132721695	132721721	154	-28.16
ADediting_330715	chr12_132721753_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3157-5p	chr12	132721747	132721753	7mer-m8	132721732	132721754	155	-20.09
ADediting_330715	chr12_132721753_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-34a-3p	chr12	132721749	132721755	7mer-m8	132721734	132721756	157	-11.8
ADediting_330716	chr12_132721754_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-548ae-3p	chr12	132721752	132721758	7mer-m8	132721738	132721759	143	-6.93
ADediting_330716	chr12_132721754_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-548ah-3p	chr12	132721752	132721758	7mer-m8	132721736	132721759	150	-7.88
ADediting_330716	chr12_132721754_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-548aj-3p	chr12	132721752	132721758	7mer-m8	132721738	132721759	143	-7.83
ADediting_330716	chr12_132721754_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-548am-3p	chr12	132721752	132721758	7mer-m8	132721736	132721759	150	-7.23
ADediting_330716	chr12_132721754_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-548aq-3p	chr12	132721752	132721758	7mer-m8	132721737	132721759	143	-7.31
ADediting_330716	chr12_132721754_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-548j-3p	chr12	132721752	132721758	7mer-m8	132721739	132721759	141	-6.93
ADediting_330716	chr12_132721754_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-548x-3p	chr12	132721752	132721758	7mer-m8	132721739	132721759	143	-7.83
ADediting_330716	chr12_132721754_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-7844-5p	chr12	132721750	132721756	7mer-m8	132721736	132721757	164	-21.17
ADediting_330719	chr12_132721773_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4684-5p	chr12	132721769	132721775	7mer-m8	132721754	132721776	159	-15.66
ADediting_330719	chr12_132721773_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-593-3p	chr12	132721771	132721777	7mer-1a	132721759	132721777	140	-19.02
ADediting_330719	chr12_132721773_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6818-3p	chr12	132721771	132721777	7mer-m8	132721757	132721778	140	-12.56
ADediting_330720	chr12_132721824_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-1289	chr12	132721822	132721828	7mer-m8	132721808	132721829	154	-21.14
ADediting_330721	chr12_132721825_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4300	chr12	132721823	132721830	8mer-1a	132721811	132721830	149	-22.2
ADediting_330721	chr12_132721825_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-5591-5p	chr12	132721823	132721830	8mer-1a	132721808	132721830	141	-20.34
ADediting_330721	chr12_132721825_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6726-5p	chr12	132721823	132721830	8mer-1a	132721809	132721830	156	-26.8
ADediting_330721	chr12_132721825_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-920	chr12	132721823	132721830	8mer-1a	132721812	132721830	152	-22.34
ADediting_330722	chr12_132721831_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6771-5p	chr12	132721825	132721831	7mer-m8	132721812	132721832	154	-26.53
ADediting_330724	chr12_132721842_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6776-3p	chr12	132721837	132721843	7mer-m8	132721822	132721844	140	-12.6
ADediting_330725	chr12_132721865_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3189-3p	chr12	132721859	132721865	7mer-m8	132721843	132721866	149	-20.43
ADediting_330725	chr12_132721865_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6813-3p	chr12	132721860	132721866	7mer-m8	132721847	132721867	140	-16.1
ADediting_330729	chr12_132722331_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-17-3p	chr12	132722324	132722330	7mer-m8	132722310	132722331	150	-17.74
ADediting_330729	chr12_132722331_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-485-5p	chr12	132722328	132722334	7mer-m8	132722315	132722335	153	-20.87
ADediting_330729	chr12_132722331_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6884-5p	chr12	132722328	132722334	7mer-m8	132722312	132722335	150	-25.7
ADediting_330733	chr12_132722368_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6089	chr12	132722366	132722372	7mer-m8	132722350	132722373	164	-40
ADediting_330734	chr12_132722376_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6771-5p	chr12	132722370	132722376	7mer-m8	132722358	132722377	160	-34.33
ADediting_330736	chr12_132722380_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3614-5p	chr12	132722373	132722379	7mer-m8	132722357	132722380	152	-25.27
ADediting_330736	chr12_132722380_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4691-3p	chr12	132722377	132722383	7mer-m8	132722357	132722384	150	-26.36
ADediting_330738	chr12_132722416_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3157-5p	chr12	132722410	132722416	7mer-m8	132722395	132722417	163	-23.67
ADediting_330738	chr12_132722416_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-34a-3p	chr12	132722412	132722418	7mer-m8	132722397	132722419	153	-11.29
ADediting_330739	chr12_132722417_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-548ae-3p	chr12	132722415	132722421	7mer-m8	132722401	132722422	143	-6.93
ADediting_330739	chr12_132722417_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-548ah-3p	chr12	132722415	132722421	7mer-m8	132722399	132722422	146	-7.88
ADediting_330739	chr12_132722417_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-548aj-3p	chr12	132722415	132722421	7mer-m8	132722401	132722422	143	-7.83
ADediting_330739	chr12_132722417_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-548am-3p	chr12	132722415	132722421	7mer-m8	132722399	132722422	146	-7.4
ADediting_330739	chr12_132722417_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-548aq-3p	chr12	132722415	132722421	7mer-m8	132722400	132722422	143	-7.31
ADediting_330739	chr12_132722417_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-548j-3p	chr12	132722415	132722421	7mer-m8	132722402	132722422	141	-6.93
ADediting_330739	chr12_132722417_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-548x-3p	chr12	132722415	132722421	7mer-m8	132722402	132722422	143	-7.83
ADediting_330739	chr12_132722417_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-7844-5p	chr12	132722413	132722419	7mer-m8	132722399	132722420	160	-17.88
ADediting_330740	chr12_132722424_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3613-3p	chr12	132722417	132722423	7mer-m8	132722402	132722424	145	-10.61
ADediting_330744	chr12_132722472_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-28-5p	chr12	132722470	132722476	7mer-m8	132722457	132722477	151	-22.03
ADediting_330744	chr12_132722472_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3139	chr12	132722470	132722476	7mer-m8	132722455	132722477	165	-26.52
ADediting_330744	chr12_132722472_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-708-5p	chr12	132722470	132722476	7mer-m8	132722456	132722477	150	-22.21

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

ADeditom_ID	Position	ENSG	ENST	Transcript name	miRNA ID	Chromosome	Targt	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
ADediting_1531720	chr12_132721554_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-5190	chr12	132721550	132721556	7mer-m8	132721537	132721557	151	-16.46
ADediting_1531721	chr12_132721632_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-5189-5p	chr12	132721626	132721632	7mer-m8	132721611	132721633	152	-22.82
ADediting_1531721	chr12_132721632_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-612	chr12	132721626	132721632	7mer-m8	132721608	132721633	154	-24.12
ADediting_1531721	chr12_132721632_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-661	chr12	132721628	132721634	7mer-m8	132721612	132721635	147	-17.4
ADediting_1531721	chr12_132721632_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6860	chr12	132721626	132721632	7mer-m8	132721614	132721633	149	-20.71
ADediting_1531721	chr12_132721632_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-939-3p	chr12	132721627	132721633	7mer-m8	132721614	132721634	140	-15.63
ADediting_1612693	chr12_132721334_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6716-5p	chr12	132721333	132721339	7mer-1a	132721320	132721339	142	-27.1
ADediting_330674	chr12_132721316_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6529-3p	chr12	132721312	132721318	7mer-m8	132721298	132721319	141	-12.43
ADediting_330674	chr12_132721316_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6889-3p	chr12	132721312	132721318	7mer-m8	132721300	132721319	145	-20.56
ADediting_330675	chr12_132721318_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4252	chr12	132721316	132721322	7mer-m8	132721304	132721323	154	-21.53
ADediting_330675	chr12_132721318_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6529-3p	chr12	132721312	132721318	7mer-m8	132721298	132721319	141	-12.43
ADediting_330675	chr12_132721318_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6889-3p	chr12	132721312	132721318	7mer-m8	132721300	132721319	145	-20.56
ADediting_330676	chr12_132721328_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-552-3p	chr12	132721326	132721333	8mer-1a	132721313	132721333	140	-14.1
ADediting_330677	chr12_132721340_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-204-3p	chr12	132721334	132721340	7mer-m8	132721321	132721341	148	-19.7
ADediting_330677	chr12_132721340_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4646-5p	chr12	132721334	132721340	7mer-m8	132721319	132721341	152	-21.82
ADediting_330678	chr12_132721344_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6869-5p	chr12	132721341	132721347	7mer-m8	132721326	132721348	146	-17.48
ADediting_330679	chr12_132721348_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-1200	chr12	132721344	132721350	7mer-m8	132721330	132721351	142	-17.86
ADediting_330679	chr12_132721348_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6869-5p	chr12	132721341	132721347	7mer-m8	132721326	132721348	146	-17.48
ADediting_330680	chr12_132721356_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3176	chr12	132721350	132721356	7mer-m8	132721338	132721357	144	-15.37
ADediting_330680	chr12_132721356_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3620-3p	chr12	132721354	132721360	7mer-m8	132721339	132721361	150	-19.51
ADediting_330680	chr12_132721356_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3922-3p	chr12	132721350	132721356	7mer-m8	132721335	132721357	147	-18.43
ADediting_330680	chr12_132721356_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6878-3p	chr12	132721349	132721355	7mer-m8	132721336	132721356	146	-18.75
ADediting_330681	chr12_132721370_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-1245a	chr12	132721365	132721371	7mer-m8	132721352	132721372	141	-18.36
ADediting_330683	chr12_132721380_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-1200	chr12	132721376	132721382	7mer-m8	132721362	132721383	153	-28.41
ADediting_330685	chr12_132721430_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6832-5p	chr12	132721424	132721430	7mer-m8	132721409	132721431	140	-22
ADediting_330690	chr12_132721437_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4742-3p	chr12	132721435	132721442	8mer-1a	132721420	132721442	142	-10.99
ADediting_330691	chr12_132721439_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4742-3p	chr12	132721435	132721442	8mer-1a	132721420	132721442	142	-10.99
ADediting_330692	chr12_132721441_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-148b-5p	chr12	132721439	132721445	7mer-m8	132721426	132721446	146	-12.21
ADediting_330692	chr12_132721441_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4742-3p	chr12	132721435	132721442	8mer-1a	132721420	132721442	142	-10.99
ADediting_330692	chr12_132721441_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6874-3p	chr12	132721439	132721445	7mer-m8	132721425	132721446	153	-10.06
ADediting_330695	chr12_132721471_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4777-5p	chr12	132721466	132721472	7mer-m8	132721450	132721473	150	-20
ADediting_330695	chr12_132721471_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-517-5p	chr12	132721467	132721473	7mer-m8	132721453	132721474	150	-15.69
ADediting_330695	chr12_132721471_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-5684	chr12	132721468	132721474	7mer-m8	132721457	132721475	142	-11.83
ADediting_330696	chr12_132721473_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4777-5p	chr12	132721466	132721472	7mer-m8	132721450	132721473	150	-20
ADediting_330696	chr12_132721473_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-517-5p	chr12	132721467	132721473	7mer-m8	132721453	132721474	150	-15.69
ADediting_330696	chr12_132721473_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-5684	chr12	132721468	132721474	7mer-m8	132721457	132721475	142	-11.83
ADediting_330697	chr12_132721483_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-562	chr12	132721479	132721485	7mer-m8	132721467	132721486	150	-13.17
ADediting_330697	chr12_132721483_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-5697	chr12	132721480	132721486	7mer-m8	132721466	132721487	146	-14.21
ADediting_330698	chr12_132721490_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-150-5p	chr12	132721484	132721490	7mer-m8	132721470	132721491	140	-13.79
ADediting_330698	chr12_132721490_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6778-3p	chr12	132721486	132721492	7mer-m8	132721473	132721493	140	-14.56
ADediting_330700	chr12_132721509_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-1245a	chr12	132721504	132721510	7mer-m8	132721491	132721511	153	-19.08
ADediting_330700	chr12_132721509_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-8079	chr12	132721504	132721510	7mer-m8	132721492	132721511	149	-13.16
ADediting_330701	chr12_132721522_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4267	chr12	132721520	132721527	8mer-1a	132721512	132721527	146	-19.76
ADediting_330701	chr12_132721522_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6736-3p	chr12	132721519	132721525	7mer-m8	132721506	132721526	141	-22.35
ADediting_330702	chr12_132721535_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-1184	chr12	132721529	132721535	7mer-m8	132721514	132721536	144	-20.47
ADediting_330702	chr12_132721535_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4418	chr12	132721530	132721536	7mer-m8	132721520	132721537	152	-23.55
ADediting_330702	chr12_132721535_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-509-3-5p	chr12	132721530	132721536	7mer-m8	132721516	132721537	142	-20.37
ADediting_330702	chr12_132721535_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-509-5p	chr12	132721530	132721536	7mer-m8	132721517	132721537	148	-18.91
ADediting_330702	chr12_132721535_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-7156-3p	chr12	132721528	132721534	7mer-m8	132721513	132721535	145	-24.1
ADediting_330704	chr12_132721546_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4705	chr12	132721542	132721548	7mer-m8	132721529	132721549	153	-16.31
ADediting_330708	chr12_132721668_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-377-5p	chr12	132721666	132721672	7mer-m8	132721650	132721673	150	-21.59
ADediting_330708	chr12_132721668_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6086	chr12	132721666	132721672	7mer-m8	132721654	132721673	154	-22.96
ADediting_330709	chr12_132721669_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-377-5p	chr12	132721666	132721672	7mer-m8	132721650	132721673	150	-21.59
ADediting_330709	chr12_132721669_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6086	chr12	132721666	132721672	7mer-m8	132721654	132721673	154	-22.96
ADediting_330710	chr12_132721689_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3614-5p	chr12	132721686	132721692	7mer-1a	132721669	132721692	151	-22.59
ADediting_330711	chr12_132721693_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-34b-3p	chr12	132721688	132721694	7mer-m8	132721672	132721695	148	-11.44
ADediting_330712	chr12_132721706_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4649-3p	chr12	132721700	132721706	7mer-m8	132721687	132721707	140	-14.11
ADediting_330712	chr12_132721706_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-7160-5p	chr12	132721701	132721707	7mer-m8	132721688	132721708	146	-18.13
ADediting_330713	chr12_132721717_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-5690	chr12	132721714	132721720	7mer-m8	132721701	132721721	145	-16.75
ADediting_330719	chr12_132721773_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-511-5p	chr12	132721771	132721777	7mer-m8	132721759	132721778	142	-8.44
ADediting_330722	chr12_132721831_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-377-5p	chr12	132721829	132721836	8mer-1a	132721814	132721836	141	-13.21
ADediting_330722	chr12_132721831_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4425	chr12	132721826	132721832	7mer-m8	132721814	132721833	150	-19.48
ADediting_330722	chr12_132721831_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6086	chr12	132721829	132721836	8mer-1a	132721817	132721836	155	-25.91
ADediting_330722	chr12_132721831_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-887-5p	chr12	132721825	132721831	7mer-m8	132721815	132721832	143	-15.19
ADediting_330722	chr12_132721831_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-92a-1-5p	chr12	132721827	132721833	7mer-m8	132721810	132721834	149	-22.77
ADediting_330723	chr12_132721837_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3622a-3p	chr12	132721834	132721841	8mer-1a	132721820	132721841	140	-12.75
ADediting_330723	chr12_132721837_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3622b-3p	chr12	132721834	132721841	8mer-1a	132721821	132721841	147	-16.66
ADediting_330723	chr12_132721837_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-7162-3p	chr12	132721831	132721837	7mer-m8	132721819	132721838	143	-16.6
ADediting_330729	chr12_132722331_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-377-5p	chr12	132722328	132722334	7mer-m8	132722312	132722335	150	-19.39
ADediting_330729	chr12_132722331_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6086	chr12	132722328	132722334	7mer-m8	132722316	132722335	150	-21.06
ADediting_330729	chr12_132722331_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6516-5p	chr12	132722324	132722330	7mer-m8	132722309	132722331	144	-14.69
ADediting_330730	chr12_132722350_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-5707	chr12	132722347	132722354	8mer-1a	132722333	132722354	152	-17.72
ADediting_330731	chr12_132722351_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-5707	chr12	132722347	132722354	8mer-1a	132722333	132722354	152	-17.72
ADediting_330732	chr12_132722352_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-5707	chr12	132722347	132722354	8mer-1a	132722333	132722354	152	-17.72
ADediting_330733	chr12_132722368_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4478	chr12	132722365	132722371	7mer-m8	132722357	132722372	149	-25.05
ADediting_330733	chr12_132722368_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4649-3p	chr12	132722362	132722368	7mer-m8	132722349	132722369	140	-14.11
ADediting_330733	chr12_132722368_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-7160-5p	chr12	132722363	132722369	7mer-m8	132722350	132722370	146	-18.5
ADediting_330734	chr12_132722376_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-12126	chr12	132722372	132722379	8mer-1a	132722356	132722379	147	-13.23
ADediting_330734	chr12_132722376_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-30b-3p	chr12	132722369	132722376	8mer-1a	132722355	132722376	151	-15.38
ADediting_330734	chr12_132722376_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3689a-3p	chr12	132722369	132722376	8mer-1a	132722356	132722376	147	-18.72
ADediting_330734	chr12_132722376_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3689b-3p	chr12	132722369	132722376	8mer-1a	132722356	132722376	147	-17.55
ADediting_330734	chr12_132722376_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3689c	chr12	132722369	132722376	8mer-1a	132722356	132722376	147	-17.55
ADediting_330734	chr12_132722376_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6779-5p	chr12	132722369	132722376	8mer-1a	132722358	132722376	148	-22.58
ADediting_330734	chr12_132722376_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-6780a-5p	chr12	132722369	132722376	8mer-1a	132722353	132722376	152	-25.37
ADediting_330734	chr12_132722376_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-887-5p	chr12	132722370	132722376	7mer-m8	132722358	132722377	143	-19.73
ADediting_330735	chr12_132722377_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-12126	chr12	132722372	132722379	8mer-1a	132722356	132722379	147	-13.23
ADediting_330735	chr12_132722377_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-887-5p	chr12	132722370	132722376	7mer-m8	132722358	132722377	143	-19.73
ADediting_330736	chr12_132722380_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-5690	chr12	132722377	132722383	7mer-m8	132722364	132722384	145	-16.74
ADediting_330742	chr12_132722433_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-3675-3p	chr12	132722431	132722437	7mer-m8	132722417	132722438	145	-12.58
ADediting_330742	chr12_132722433_+	ENSG00000247077.7	ENST00000498926.7	PGAM5-203	hsa-miR-4684-5p	chr12	132722430	132722436	7mer-m8	132722416	132722437	151	-11.86

RNA A-to-I editing in lncRNA gained miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_1337757

chr7_5495852_-

ENSG00000247077.7

ENST00000317555.6

PGAM5-201

hsa-miR-589-3p

chr12

132718954

132718960

7mer-m8

132718938

132718961

140

-15.23

ADediting_1535954

chr14_101045974_+

ENSG00000247077.7

ENST00000498926.7

PGAM5-203

hsa-miR-381-3p

chr12

132721328

132721334

7mer-m8

132721313

132721335

155

-19.55

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

Differentially expressed mRNA-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for PGAM5

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000498926.7	protein_coding
ENST00000543955.5	protein_coding

RNA A-to-I editing in miRNA.

ADeditom_ID

ENST

mir_ID

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

RNA A-to-I editing in mRNA.

ADeditom_ID	ENST	Editing_Information	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
ADediting_330674	ENST00000498926.7	chr12_132721316_+	1393	-1289.10	-1289.50	-1324.70
ADediting_330675	ENST00000498926.7	chr12_132721318_+	1395	-1294.70	-1289.50	-1324.70
ADediting_330676	ENST00000498926.7	chr12_132721328_+	1405	-1289.10	-1289.50	-1324.70
ADediting_1612693	ENST00000498926.7	chr12_132721334_+	1411	-1289.20	-1289.50	-1324.70
ADediting_330677	ENST00000498926.7	chr12_132721340_+	1417	-1288.80	-1289.50	-1324.70
ADediting_330678	ENST00000498926.7	chr12_132721344_+	1421	-1289.10	-1289.50	-1324.70
ADediting_330679	ENST00000498926.7	chr12_132721348_+	1425	-1293.10	-1289.50	-1324.70
ADediting_330680	ENST00000498926.7	chr12_132721356_+	1433	-1288.70	-1289.50	-1324.70
ADediting_330681	ENST00000498926.7	chr12_132721370_+	1447	-1289.10	-1289.50	-1324.70
ADediting_330682	ENST00000498926.7	chr12_132721375_+	1452	-1288.60	-1289.50	-1324.70
ADediting_330683	ENST00000498926.7	chr12_132721380_+	1457	-1293.10	-1289.50	-1324.70
ADediting_330684	ENST00000498926.7	chr12_132721388_+	1465	-1295.50	-1289.50	-1324.70
ADediting_1531719	ENST00000498926.7	chr12_132721389_+	1466	-1289.40	-1289.50	-1324.70
ADediting_330685	ENST00000498926.7	chr12_132721430_+	1507	-1289.50	-1289.50	-1324.70
ADediting_330686	ENST00000498926.7	chr12_132721433_+	1510	-1289.60	-1289.50	-1324.70
ADediting_330687	ENST00000498926.7	chr12_132721434_+	1511	-1289.60	-1289.50	-1324.70
ADediting_330688	ENST00000498926.7	chr12_132721435_+	1512	-1289.60	-1289.50	-1324.70
ADediting_330689	ENST00000498926.7	chr12_132721436_+	1513	-1289.60	-1289.50	-1324.70
ADediting_330690	ENST00000498926.7	chr12_132721437_+	1514	-1289.50	-1289.50	-1324.70
ADediting_330691	ENST00000498926.7	chr12_132721439_+	1516	-1289.50	-1289.50	-1324.70
ADediting_330692	ENST00000498926.7	chr12_132721441_+	1518	-1288.70	-1289.50	-1324.70
ADediting_330693	ENST00000498926.7	chr12_132721448_+	1525	-1289.20	-1289.50	-1324.70
ADediting_330694	ENST00000498926.7	chr12_132721467_+	1544	-1292.50	-1289.50	-1324.70
ADediting_330695	ENST00000498926.7	chr12_132721471_+	1548	-1292.70	-1289.50	-1324.70
ADediting_330696	ENST00000498926.7	chr12_132721473_+	1550	-1288.10	-1289.50	-1324.70
ADediting_1612694	ENST00000498926.7	chr12_132721479_+	1556	-1288.80	-1289.50	-1324.70
ADediting_330697	ENST00000498926.7	chr12_132721483_+	1560	-1289.50	-1289.50	-1324.70
ADediting_330698	ENST00000498926.7	chr12_132721490_+	1567	-1288.60	-1289.50	-1324.70
ADediting_330699	ENST00000498926.7	chr12_132721496_+	1573	-1288.60	-1289.50	-1324.70
ADediting_330700	ENST00000498926.7	chr12_132721509_+	1586	-1289.10	-1289.50	-1324.70
ADediting_330701	ENST00000498926.7	chr12_132721522_+	1599	-1290.30	-1289.50	-1324.70
ADediting_330702	ENST00000498926.7	chr12_132721535_+	1612	-1295.70	-1289.50	-1324.70
ADediting_330703	ENST00000498926.7	chr12_132721539_+	1616	-1288.60	-1289.50	-1324.70
ADediting_330704	ENST00000498926.7	chr12_132721546_+	1623	-1288.90	-1289.50	-1324.70
ADediting_1531720	ENST00000498926.7	chr12_132721554_+	1631	-1289.10	-1289.50	-1324.70
ADediting_330705	ENST00000498926.7	chr12_132721559_+	1636	-1289.10	-1289.50	-1324.70
ADediting_1531721	ENST00000498926.7	chr12_132721632_+	1709	-1288.80	-1289.50	-1324.70
ADediting_330706	ENST00000498926.7	chr12_132721653_+	1730	-1289.00	-1289.50	-1324.70
ADediting_330707	ENST00000498926.7	chr12_132721663_+	1740	-1289.10	-1289.50	-1324.70
ADediting_330708	ENST00000498926.7	chr12_132721668_+	1745	-1288.80	-1289.50	-1324.70
ADediting_330709	ENST00000498926.7	chr12_132721669_+	1746	-1296.20	-1289.50	-1324.70
ADediting_330710	ENST00000498926.7	chr12_132721689_+	1766	-1289.20	-1289.50	-1324.70
ADediting_330711	ENST00000498926.7	chr12_132721693_+	1770	-1288.90	-1289.50	-1324.70
ADediting_330712	ENST00000498926.7	chr12_132721706_+	1783	-1288.80	-1289.50	-1324.70
ADediting_330713	ENST00000498926.7	chr12_132721717_+	1794	-1289.20	-1289.50	-1324.70
ADediting_330714	ENST00000498926.7	chr12_132721729_+	1806	-1289.50	-1289.50	-1324.70
ADediting_1612695	ENST00000498926.7	chr12_132721745_+	1822	-1288.50	-1289.50	-1324.70
ADediting_330715	ENST00000498926.7	chr12_132721753_+	1830	-1289.60	-1289.50	-1324.70
ADediting_330716	ENST00000498926.7	chr12_132721754_+	1831	-1289.20	-1289.50	-1324.70
ADediting_330717	ENST00000498926.7	chr12_132721763_+	1840	-1289.50	-1289.50	-1324.70
ADediting_330718	ENST00000498926.7	chr12_132721769_+	1846	-1289.20	-1289.50	-1324.70
ADediting_330719	ENST00000498926.7	chr12_132721773_+	1850	-1295.90	-1289.50	-1324.70
ADediting_330720	ENST00000498926.7	chr12_132721824_+	1901	-1289.00	-1289.50	-1324.70
ADediting_330721	ENST00000498926.7	chr12_132721825_+	1902	-1289.50	-1289.50	-1324.70
ADediting_330722	ENST00000498926.7	chr12_132721831_+	1908	-1292.50	-1289.50	-1324.70
ADediting_330723	ENST00000498926.7	chr12_132721837_+	1914	-1288.70	-1289.50	-1324.70
ADediting_330724	ENST00000498926.7	chr12_132721842_+	1919	-1288.90	-1289.50	-1324.70
ADediting_330725	ENST00000498926.7	chr12_132721865_+	1942	-1290.30	-1289.50	-1324.70
ADediting_330726	ENST00000498926.7	chr12_132721877_+	1954	-1289.20	-1289.50	-1324.70
ADediting_330727	ENST00000498926.7	chr12_132721878_+	1955	-1292.10	-1289.50	-1324.70
ADediting_330728	ENST00000498926.7	chr12_132721879_+	1956	-1289.50	-1289.50	-1324.70
ADediting_330729	ENST00000498926.7	chr12_132722331_+	2408	-1289.50	-1289.50	-1324.70
ADediting_330730	ENST00000498926.7	chr12_132722350_+	2427	-1290.50	-1289.50	-1324.70
ADediting_330731	ENST00000498926.7	chr12_132722351_+	2428	-1295.70	-1289.50	-1324.70
ADediting_330732	ENST00000498926.7	chr12_132722352_+	2429	-1295.40	-1289.50	-1324.70
ADediting_330733	ENST00000498926.7	chr12_132722368_+	2445	-1288.80	-1289.50	-1324.70
ADediting_330734	ENST00000498926.7	chr12_132722376_+	2453	-1288.80	-1289.50	-1324.70
ADediting_330735	ENST00000498926.7	chr12_132722377_+	2454	-1293.10	-1289.50	-1324.70
ADediting_330736	ENST00000498926.7	chr12_132722380_+	2457	-1289.50	-1289.50	-1324.70
ADediting_330737	ENST00000498926.7	chr12_132722392_+	2469	-1289.50	-1289.50	-1324.70
ADediting_330738	ENST00000498926.7	chr12_132722416_+	2493	-1288.60	-1289.50	-1324.70
ADediting_330739	ENST00000498926.7	chr12_132722417_+	2494	-1287.90	-1289.50	-1324.70
ADediting_330740	ENST00000498926.7	chr12_132722424_+	2501	-1288.50	-1289.50	-1324.70
ADediting_330741	ENST00000498926.7	chr12_132722430_+	2507	-1290.40	-1289.50	-1324.70
ADediting_330742	ENST00000498926.7	chr12_132722433_+	2510	-1289.10	-1289.50	-1324.70
ADediting_330743	ENST00000498926.7	chr12_132722447_+	2524	-1289.80	-1289.50	-1324.70
ADediting_330744	ENST00000498926.7	chr12_132722472_+	2549	-1292.60	-1289.50	-1324.70
ADediting_330649	ENST00000543955.5	chr12_132711519_+	438	-719.90	-719.30	-721.20
ADediting_330650	ENST00000543955.5	chr12_132711600_+	519	-719.20	-719.30	-721.20
ADediting_1531718	ENST00000543955.5	chr12_132711671_+	590	-719.30	-719.30	-721.20

RNA A-to-I editing in lncRNA.

ADeditom_ID

ENST

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for PGAM5

Correlation between ADAR gene expression and RNA editing frequency

Tissue	ADeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
STG	ADediting_330675	chr12_132721318_+	6.49544528764964e-05	0.421605297614629	0.000103958953757461	0.410773215955848	0.0206053898229173	-0.252281729426711
CER	ADediting_330679	chr12_132721348_+	0.0118424837873834	0.205023463340474	0.000145846758067632	0.305228147695591	0.0556988721692564	0.15657202630748
CER	ADediting_330680	chr12_132721356_+	0.0408883641326518	0.167167611207007	1.18677955520375e-07	0.416088734482428	0.246701245980183	0.0951641477410292
STG	ADediting_330681	chr12_132721370_+	0.00161840224467747	0.338815759519918	0.00695253640078983	0.292412058264808	0.213515475705383	-0.137139365962866
STG	ADediting_330683	chr12_132721380_+	0.000614587199476758	0.366129017785834	0.000641043712932398	0.364988985034236	0.0144642285628799	-0.26598832179543
CER	ADediting_330684	chr12_132721388_+	0.0124351004637036	0.20364766557934	7.00735271813392e-07	0.39202251774621	0.0280228190218701	0.179424232117191
CER	ADediting_330695	chr12_132721471_+	0.00362372627023087	0.236140587330566	1.8803077657946e-06	0.377774319157995	0.73330797948307	0.0280495376585734
CER	ADediting_330697	chr12_132721483_+	0.00331039748523057	0.238360151242375	2.48709158250318e-08	0.43581442618841	0.95882956860628	0.00425048992784025
CER	ADediting_330700	chr12_132721509_+	0.0130487724836854	0.202282284314069	6.28828889447305e-05	0.320746953172228	0.534675497025499	0.051089285934807
CER	ADediting_330702	chr12_132721535_+	1.15253755792422e-06	0.384923615283118	9.70337874313428e-11	0.497157576885801	0.308174094594112	-0.0837603430385444
TCX	ADediting_330702	chr12_132721535_+	0.00884620153987166	0.213075999381415	6.95712993933638e-11	0.500478474746534	7.91617036878226e-08	-0.42132213646758
STG	ADediting_330702	chr12_132721535_+	0.144430092907695	0.16061425918481	0.00183173766703095	0.33514076105796	0.00484363292344713	-0.304610732052097
DLPFC	ADediting_330709	chr12_132721669_+	0.00163556167367369	0.178165417259683	1.39749236014842e-08	0.315263244984744	0.420553416087518	0.0459084728755173
CER	ADediting_330709	chr12_132721669_+	0.00122844937378438	0.261487534844696	4.52292576527209e-08	0.428413461872764	0.0311544645649128	-0.176058645605913
TCX	ADediting_330709	chr12_132721669_+	0.0125855455240057	0.203307562332754	4.83302256741857e-12	0.525878680902059	1.40543232766846e-05	-0.346457785357576
CER	ADediting_330710	chr12_132721689_+	0.000191242881791556	0.300040621590715	1.06030700492598e-05	0.351049197096688	0.428420369777196	0.0651343503474492
STG	ADediting_330710	chr12_132721689_+	0.0827557934153995	0.190411859487636	0.000147021271364795	0.402547470086638	0.0131696584128715	-0.269510231720069
CER	ADediting_330712	chr12_132721706_+	0.00272594856581661	0.24306176111729	5.29599368911053e-06	0.362064607367947	0.319097046318916	0.0818971522016987
CER	ADediting_330713	chr12_132721717_+	0.0227067901268438	0.185955058994121	0.000186099822076396	0.300566887562078	0.103231133992815	0.1335594327621
STG	ADediting_330715	chr12_132721753_+	0.000258649533388864	0.388664305111196	0.0012002212995113	0.347509739245443	0.623830874265883	-0.054284013216203
STG	ADediting_330717	chr12_132721763_+	0.00116583464671499	0.348342150019191	0.00130386540863013	0.345125449980565	0.502455088437644	0.0741825589486126
STG	ADediting_330723	chr12_132721837_+	0.00760159726509722	0.289319709429684	1.15457338887637e-05	0.458499577384162	0.236620307644989	-0.130530414615156
STG	ADediting_330724	chr12_132721842_+	0.00473333869832367	0.305371242898334	0.00437549174915774	0.307952102659314	0.469192215177353	-0.0800449350650381
CER	ADediting_330728	chr12_132721879_+	0.00174887449619698	0.253485648289611	9.96789127144412e-06	0.352046240706822	0.637083351932631	0.0388310356755691
CER	ADediting_330729	chr12_132722331_+	0.0381753463200147	0.169448585131789	1.68722404952447e-05	0.343441350979679	0.727680750143287	0.0286653702279573
CER	ADediting_330732	chr12_132722352_+	0.00677921815366278	0.220188463654064	4.0934453573873e-06	0.366049844868854	0.00163144543659867	0.255080028356513
CER	ADediting_330734	chr12_132722376_+	0.00868069678088692	0.213587887656728	0.00010897446450955	0.310701637528171	0.112804593262396	0.13001032433094
CER	ADediting_330741	chr12_132722430_+	0.0381376076011449	0.169481262851453	2.96738678233455e-09	0.460780344667411	0.00368661434111375	0.235716038324502

Correlation between ADAR gene expression and this gene's expression

Tissue	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
DLPFC	1.60582432131946e-12	0.387080212376342	5.14703174392786e-05	0.227847704738545	7.35067697480271e-34	0.616644460735379
AC	8.89301814026052e-99	0.913383767516704	1.54844523705847e-70	0.848627939460276	3.40437809779407e-10	0.38374310049914
PCC	8.09459762364884e-62	0.876195581631791	2.63775815484975e-73	0.907943370090543	0.5766817262823	0.0406427958985341
CER	2.14351131905369e-05	0.339442577118123	3.8627716154399e-10	0.482974004407674	0.712450462078805	0.030340253443644
TCX	6.48125639660879e-19	0.643657520211802	3.65674409357142e-29	0.757172192767827	0.0219064593191705	-0.187049774311121
FP	5.88775801297282e-21	0.628504372313552	6.97153448782067e-26	0.683878765095174	0.160540284108909	0.105628245302942
IFG	1.44066905308123e-06	0.801880416873535	2.83017358500116e-06	0.788612531366826	0.815106978907313	-0.0492622866743205
PG	3.84323016679407e-12	0.480628646669194	8.01594420435074e-18	0.57589671246086	0.0910058467550016	-0.124282180913229
STG	4.13104955178067e-22	0.825917730260353	2.11579179599644e-15	0.73346437115555	0.769800449066936	-0.0324063834287344

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Relation with AD stages for PGAM5

Correlation between AD stages and RNA editing frequency

Tissue	ADeditomID	position	P-val	Coeff.
CER	ADediting_330680	chr12_132721356_+	0.00122081132297347	0.307202923073462
CER	ADediting_330732	chr12_132722352_+	0.000283040943142754	0.342678854796154
CER	ADediting_330741	chr12_132722430_+	0.00033225446963109	0.338989668128244
IFG	ADediting_330675	chr12_132721318_+	0.00887152063421571	-0.512090603463099
IFG	ADediting_330744	chr12_132722472_+	0.0100551275039657	0.504861263675046

Correlation between AD stages and this gene's expression

Tissue

P-val

Coeff.

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RelatedDrugs for PGAM5

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for PGAM5

Diseases associated with this gene.
(DisGeNet 4.0)

Gene

Disease ID

Disease name

# pubmeds

Source

Home

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Statistics

Landscape

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Gene summary for PGAM5

RNA A-to-I events for PGAM5

RNA editing positional annotations for PGAM5 using Annovar

RNA A-to-I editing events in the alternative splicing sites for PGAM5

Differntial gene expression between RNA A-to-I edited versus non-edited samples for PGAM5

Protein coding region RNA A-to-I editings for PGAM5

The effects of the RNA editing to the miRNA binding sites for PGAM5

The effects of the RNA editing to the stability of the RNA structures for PGAM5

Relation with ADAR for PGAM5

Relation with AD stages for PGAM5

RelatedDrugs for PGAM5

RelatedDiseases for PGAM5

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited versus non-edited samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with AD stages
	Related drugs with this gene
	Related diseases with this gene