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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for DIO2 |
 Gene summary |
| Gene information | Gene symbol | DIO2 | Gene ID | 1734 |
| Gene name | iodothyronine deiodinase 2 | |
| Synonyms | 5DII|D2|DIOII|SelY|TXDI2 | |
| Cytomap | 14q31.1 | |
| Type of gene | protein-coding | |
| Description | type II iodothyronine deiodinasedeiodinase, iodothyronine type IIdeiodinase-2deiodonase-2thyroxine deiodinase, type IItype 2 DItype 2 iodothyronine deiodinasetype-II 5'-deiodinasetype-II 5'deiodinase | |
| Modification date | 20200313 | |
| UniProtAcc | Q92813, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| DIO2 | GO:0042403 | thyroid hormone metabolic process | 19651899 |
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RNA A-to-I events for DIO2 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_455673(80197776, -), |
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RNA editing positional annotations for DIO2 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_455673 | chr14_80197776_- | UTR3 |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
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RNA A-to-I editing events in the alternative splicing sites for DIO2 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for DIO2 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for DIO2 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for DIO2 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_455673 | chr14_80197776_- | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-6715a-3p | chr14 | 80197771 | 80197777 | 7mer-m8 | 80197770 | 80197789 | 161 | -18.59 |
| ADediting_455673 | chr14_80197776_- | ENSG00000211448.12 | ENST00000438257.8 | DIO2-202 | hsa-miR-6715a-3p | chr14 | 80197771 | 80197777 | 7mer-m8 | 80197770 | 80197789 | 161 | -18.59 |
| ADediting_455673 | chr14_80197776_- | ENSG00000211448.12 | ENST00000557010.5 | DIO2-210 | hsa-miR-6715a-3p | chr14 | 80197771 | 80197777 | 7mer-m8 | 80197770 | 80197789 | 161 | -18.59 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_455673 | chr14_80197776_- | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-3129-3p | chr14 | 80197773 | 80197779 | 7mer-m8 | 80197772 | 80197795 | 154 | -11.76 |
| ADediting_455673 | chr14_80197776_- | ENSG00000211448.12 | ENST00000438257.8 | DIO2-202 | hsa-miR-3129-3p | chr14 | 80197773 | 80197779 | 7mer-m8 | 80197772 | 80197795 | 154 | -11.76 |
| ADediting_455673 | chr14_80197776_- | ENSG00000211448.12 | ENST00000557010.5 | DIO2-210 | hsa-miR-3129-3p | chr14 | 80197773 | 80197779 | 7mer-m8 | 80197772 | 80197795 | 154 | -11.76 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-4477b | chr14 | 80198765 | 80198772 | 8mer-1a | 80198765 | 80198786 | 142 | -8.45 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-4477b | chr14 | 80199806 | 80199812 | 7mer-m8 | 80199805 | 80199826 | 145 | -14.34 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000211448.12 | ENST00000438257.8 | DIO2-202 | hsa-miR-4477b | chr14 | 80198765 | 80198772 | 8mer-1a | 80198765 | 80198786 | 142 | -8.45 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000211448.12 | ENST00000438257.8 | DIO2-202 | hsa-miR-4477b | chr14 | 80199806 | 80199812 | 7mer-m8 | 80199805 | 80199826 | 145 | -14.34 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000211448.12 | ENST00000557010.5 | DIO2-210 | hsa-miR-4477b | chr14 | 80198765 | 80198772 | 8mer-1a | 80198765 | 80198786 | 142 | -8.45 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000211448.12 | ENST00000557010.5 | DIO2-210 | hsa-miR-4477b | chr14 | 80199806 | 80199812 | 7mer-m8 | 80199805 | 80199826 | 145 | -14.34 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-337-3p | chr14 | 80199046 | 80199052 | 7mer-m8 | 80199045 | 80199068 | 147 | -15.44 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000211448.12 | ENST00000438257.8 | DIO2-202 | hsa-miR-337-3p | chr14 | 80199046 | 80199052 | 7mer-m8 | 80199045 | 80199068 | 147 | -15.44 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000211448.12 | ENST00000557010.5 | DIO2-210 | hsa-miR-337-3p | chr14 | 80199046 | 80199052 | 7mer-m8 | 80199045 | 80199068 | 147 | -15.44 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-641 | chr14 | 80198832 | 80198838 | 7mer-1a | 80198832 | 80198855 | 149 | -18.1 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-641 | chr14 | 80203242 | 80203248 | 7mer-m8 | 80203241 | 80203264 | 142 | -13.37 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000211448.12 | ENST00000438257.8 | DIO2-202 | hsa-miR-641 | chr14 | 80198832 | 80198838 | 7mer-1a | 80198832 | 80198855 | 149 | -18.1 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000211448.12 | ENST00000556811.5 | DIO2-209 | hsa-miR-641 | chr14 | 80203242 | 80203248 | 7mer-m8 | 80203241 | 80203264 | 142 | -13.37 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000211448.12 | ENST00000557010.5 | DIO2-210 | hsa-miR-641 | chr14 | 80198832 | 80198838 | 7mer-1a | 80198832 | 80198855 | 149 | -18.1 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-641 | chr14 | 80198605 | 80198611 | 7mer-m8 | 80198604 | 80198631 | 150 | -16.27 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000211448.12 | ENST00000438257.8 | DIO2-202 | hsa-miR-641 | chr14 | 80198605 | 80198611 | 7mer-m8 | 80198604 | 80198631 | 150 | -16.27 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000211448.12 | ENST00000557010.5 | DIO2-210 | hsa-miR-641 | chr14 | 80198605 | 80198611 | 7mer-m8 | 80198604 | 80198631 | 150 | -16.27 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-4775 | chr14 | 80200005 | 80200012 | 8mer-1a | 80200005 | 80200025 | 150 | -12.73 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-4775 | chr14 | 80200368 | 80200374 | 7mer-m8 | 80200367 | 80200387 | 149 | -9.56 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-4775 | chr14 | 80200652 | 80200658 | 7mer-m8 | 80200651 | 80200672 | 143 | -10.69 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000211448.12 | ENST00000438257.8 | DIO2-202 | hsa-miR-4775 | chr14 | 80200005 | 80200012 | 8mer-1a | 80200005 | 80200025 | 150 | -12.73 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000211448.12 | ENST00000438257.8 | DIO2-202 | hsa-miR-4775 | chr14 | 80200368 | 80200374 | 7mer-m8 | 80200367 | 80200387 | 149 | -9.56 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000211448.12 | ENST00000438257.8 | DIO2-202 | hsa-miR-4775 | chr14 | 80200652 | 80200658 | 7mer-m8 | 80200651 | 80200672 | 143 | -10.69 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000211448.12 | ENST00000557010.5 | DIO2-210 | hsa-miR-4775 | chr14 | 80200005 | 80200012 | 8mer-1a | 80200005 | 80200025 | 150 | -12.73 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000211448.12 | ENST00000557010.5 | DIO2-210 | hsa-miR-4775 | chr14 | 80200368 | 80200374 | 7mer-m8 | 80200367 | 80200387 | 149 | -9.56 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000211448.12 | ENST00000557010.5 | DIO2-210 | hsa-miR-4775 | chr14 | 80200652 | 80200658 | 7mer-m8 | 80200651 | 80200672 | 143 | -10.69 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-5585-3p | chr14 | 80199676 | 80199683 | 8mer-1a | 80199676 | 80199698 | 145 | -14.13 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-5585-3p | chr14 | 80202521 | 80202528 | 8mer-1a | 80202521 | 80202541 | 148 | -13.48 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000211448.12 | ENST00000438257.8 | DIO2-202 | hsa-miR-5585-3p | chr14 | 80199676 | 80199683 | 8mer-1a | 80199676 | 80199698 | 145 | -14.13 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000211448.12 | ENST00000438257.8 | DIO2-202 | hsa-miR-5585-3p | chr14 | 80202521 | 80202528 | 8mer-1a | 80202521 | 80202541 | 148 | -13.48 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000211448.12 | ENST00000556811.5 | DIO2-209 | hsa-miR-5585-3p | chr14 | 80202521 | 80202528 | 8mer-1a | 80202521 | 80202541 | 148 | -13.48 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000211448.12 | ENST00000557010.5 | DIO2-210 | hsa-miR-5585-3p | chr14 | 80199676 | 80199683 | 8mer-1a | 80199676 | 80199698 | 145 | -14.13 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000211448.12 | ENST00000557010.5 | DIO2-210 | hsa-miR-5585-3p | chr14 | 80202521 | 80202528 | 8mer-1a | 80202521 | 80202541 | 148 | -13.48 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-5585-3p | chr14 | 80201437 | 80201443 | 7mer-m8 | 80201436 | 80201460 | 160 | -25.47 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000211448.12 | ENST00000438257.8 | DIO2-202 | hsa-miR-5585-3p | chr14 | 80201437 | 80201443 | 7mer-m8 | 80201436 | 80201460 | 160 | -25.47 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000211448.12 | ENST00000557010.5 | DIO2-210 | hsa-miR-5585-3p | chr14 | 80201437 | 80201443 | 7mer-m8 | 80201436 | 80201460 | 160 | -25.47 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_107020 | chr1_37500952_- | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-5581-3p | chr14 | 80202864 | 80202870 | 7mer-m8 | 80202863 | 80202887 | 146 | -14.1 |
| ADediting_107020 | chr1_37500952_- | ENSG00000211448.12 | ENST00000556811.5 | DIO2-209 | hsa-miR-5581-3p | chr14 | 80202864 | 80202870 | 7mer-m8 | 80202863 | 80202887 | 146 | -14.1 |
| ADediting_107020 | chr1_37500952_- | ENSG00000211448.12 | ENST00000557125.1 | DIO2-211 | hsa-miR-5581-3p | chr14 | 80202864 | 80202870 | 7mer-m8 | 80202863 | 80202887 | 146 | -14.1 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-641 | chr14 | 80199647 | 80199653 | 7mer-m8 | 80199646 | 80199669 | 151 | -14.39 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-641 | chr14 | 80200133 | 80200139 | 7mer-m8 | 80200132 | 80200155 | 150 | -12.35 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000211448.12 | ENST00000438257.8 | DIO2-202 | hsa-miR-641 | chr14 | 80199647 | 80199653 | 7mer-m8 | 80199646 | 80199669 | 151 | -14.39 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000211448.12 | ENST00000438257.8 | DIO2-202 | hsa-miR-641 | chr14 | 80200133 | 80200139 | 7mer-m8 | 80200132 | 80200155 | 150 | -12.35 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000211448.12 | ENST00000557010.5 | DIO2-210 | hsa-miR-641 | chr14 | 80199647 | 80199653 | 7mer-m8 | 80199646 | 80199669 | 151 | -14.39 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000211448.12 | ENST00000557010.5 | DIO2-210 | hsa-miR-641 | chr14 | 80200133 | 80200139 | 7mer-m8 | 80200132 | 80200155 | 150 | -12.35 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-641 | chr14 | 80199647 | 80199653 | 7mer-m8 | 80199646 | 80199669 | 151 | -14.39 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-641 | chr14 | 80200133 | 80200139 | 7mer-m8 | 80200132 | 80200155 | 150 | -12.35 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000211448.12 | ENST00000438257.8 | DIO2-202 | hsa-miR-641 | chr14 | 80199647 | 80199653 | 7mer-m8 | 80199646 | 80199669 | 151 | -14.39 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000211448.12 | ENST00000438257.8 | DIO2-202 | hsa-miR-641 | chr14 | 80200133 | 80200139 | 7mer-m8 | 80200132 | 80200155 | 150 | -12.35 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000211448.12 | ENST00000557010.5 | DIO2-210 | hsa-miR-641 | chr14 | 80199647 | 80199653 | 7mer-m8 | 80199646 | 80199669 | 151 | -14.39 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000211448.12 | ENST00000557010.5 | DIO2-210 | hsa-miR-641 | chr14 | 80200133 | 80200139 | 7mer-m8 | 80200132 | 80200155 | 150 | -12.35 |
| ADediting_496066 | chr15_66496985_- | ENSG00000211448.12 | ENST00000422005.7 | DIO2-201 | hsa-miR-4512 | chr14 | 80198532 | 80198538 | 7mer-m8 | 80198531 | 80198552 | 141 | -24.86 |
| ADediting_496066 | chr15_66496985_- | ENSG00000211448.12 | ENST00000438257.8 | DIO2-202 | hsa-miR-4512 | chr14 | 80198532 | 80198538 | 7mer-m8 | 80198531 | 80198552 | 141 | -24.86 |
| ADediting_496066 | chr15_66496985_- | ENSG00000211448.12 | ENST00000557010.5 | DIO2-210 | hsa-miR-4512 | chr14 | 80198532 | 80198538 | 7mer-m8 | 80198531 | 80198552 | 141 | -24.86 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for DIO2 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000422005.7 | protein_coding |  |  |
| ENST00000438257.8 | protein_coding |  |  |
| ENST00000557010.5 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_455673 | ENST00000422005.7 | chr14_80197776_- | 6023 | -1772.67 | -1766.07 | -1772.67 |
| ADediting_455673 | ENST00000438257.8 | chr14_80197776_- | 5890 | -1748.67 | -1742.07 | -1748.67 |
| ADediting_455673 | ENST00000557010.5 | chr14_80197776_- | 6121 | -1844.47 | -1837.87 | -1844.47 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for DIO2 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| AC | 1.21082655007848e-12 | 0.429489568466925 | 5.33783647437069e-12 | 0.418111326435191 | 3.86635333426443e-06 | 0.287352124919884 |
| PCC | 3.01074127572852e-11 | 0.457037855512415 | 4.08180089868039e-08 | 0.384220948842664 | 0.251631732628328 | 0.083352953381316 |
| TCX | 0.630796964487678 | 0.0395568142082986 | 0.318921957676226 | 0.081926688365264 | 2.03232653829783e-06 | -0.376622991705551 |
| PG | 1.76611559697842e-09 | 0.423201134141179 | 3.92039543694849e-07 | 0.361720511896655 | 0.0564103297243635 | -0.14014409706595 |
| STG | 0.000181590593087442 | 0.397428610828337 | 0.00844831744430576 | 0.285617503632175 | 0.294205193227859 | 0.115798424476311 |
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Relation with AD stages for DIO2 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
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RelatedDrugs for DIO2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for DIO2 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| DIO2 | C0005586 | Bipolar Disorder | 1 | PSYGENET |
| DIO2 | C0014175 | Endometriosis | 1 | CTD_human |
| DIO2 | C0025500 | Mesothelioma | 1 | CTD_human |
| DIO2 | C0040128 | Thyroid Diseases | 1 | CTD_human |
| DIO2 | C0269102 | Endometrioma | 1 | CTD_human |
| DIO2 | C1510586 | Autism Spectrum Disorders | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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