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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

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The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

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Relation with AD stages

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Related drugs with this gene

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Related diseases with this gene


Gene summary for DHFR

check button Gene summary
Gene informationGene symbol

DHFR

Gene ID

1719

Gene namedihydrofolate reductase
SynonymsDHFRP1|DYR
Cytomap

5q14.1

Type of geneprotein-coding
Descriptiondihydrofolate reductase
Modification date20200315
UniProtAcc

P00374,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
DHFR

GO:0017148

negative regulation of translation

8490020

DHFR

GO:0046452

dihydrofolate metabolic process

2303423|23707606

DHFR

GO:0046653

tetrahydrofolate metabolic process

12096917|21876184

DHFR

GO:0046654

tetrahydrofolate biosynthetic process

2303423

DHFR

GO:0055114

oxidation-reduction process

23707606


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RNA A-to-I events for DHFR

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1215889(80626973, -), ADediting_1215890(80627448, -), ADediting_1215891(80627451, -), ADediting_1215892(80627454, -), ADediting_1215893(80627466, -), ADediting_1215894(80627470, -), ADediting_1215895(80627474, -), ADediting_1215896(80627478, -), ADediting_1215897(80627484, -), ADediting_1215898(80627490, -), ADediting_1215899(80627492, -), ADediting_1215900(80627502, -), ADediting_1215901(80627510, -), ADediting_1215902(80627513, -), ADediting_1215903(80627514, -), ADediting_1215904(80627515, -), ADediting_1215905(80627516, -), ADediting_1215906(80627517, -), ADediting_1215907(80627519, -), ADediting_1215908(80627522, -), ADediting_1215909(80627523, -), ADediting_1215910(80627525, -), ADediting_1215911(80627528, -), ADediting_1215912(80627534, -), ADediting_1215913(80627540, -), ADediting_1215914(80627541, -), ADediting_1215915(80627542, -), ADediting_1215916(80627547, -), ADediting_1215917(80627549, -), ADediting_1215918(80627559, -), ADediting_1215919(80627562, -), ADediting_1215920(80627569, -), ADediting_1215921(80627574, -), ADediting_1215922(80627578, -), ADediting_1215923(80627582, -), ADediting_1215924(80627583, -), ADediting_1215925(80627599, -), ADediting_1215926(80627604, -), ADediting_1215927(80627605, -), ADediting_1215928(80627611, -), ADediting_1215929(80627613, -), ADediting_1215930(80627627, -), ADediting_1215931(80627947, -), ADediting_1215932(80627959, -), ADediting_1215933(80627960, -), ADediting_1215934(80627969, -), ADediting_1215935(80627974, -), ADediting_1215936(80627982, -), ADediting_1215937(80628007, -), ADediting_1215938(80628021, -), ADediting_1215939(80628024, -), ADediting_1215940(80628036, -), ADediting_1215941(80628038, -), ADediting_1215942(80628041, -), ADediting_1215943(80628047, -), ADediting_1215944(80628054, -), ADediting_1215945(80628076, -), ADediting_1215946(80628087, -), ADediting_1215947(80628093, -), ADediting_1215948(80628097, -), ADediting_1215949(80628100, -), ADediting_1215950(80628101, -), ADediting_1215951(80628126, -), ADediting_1215952(80628133, -), ADediting_1215953(80628171, -), ADediting_1215954(80628176, -), ADediting_1215955(80628179, -), ADediting_1215956(80630047, -), ADediting_1215957(80630082, -), ADediting_1215958(80630092, -), ADediting_1215959(80630099, -), ADediting_1215960(80630137, -), ADediting_1215961(80630143, -), ADediting_1215962(80630153, -), ADediting_1215963(80630178, -), ADediting_1215964(80630182, -), ADediting_1215965(80630189, -), ADediting_1215966(80630203, -), ADediting_1215967(80630208, -), ADediting_1215968(80630439, -), ADediting_1215969(80630491, -), ADediting_1215970(80630501, -), ADediting_1215971(80630507, -), ADediting_1215972(80630563, -), ADediting_1215973(80630596, -), ADediting_1215974(80631039, -), ADediting_1215975(80631158, -), ADediting_1215976(80631210, -), ADediting_1215977(80633422, -), ADediting_1215978(80633434, -), ADediting_1215979(80633460, -), ADediting_1215980(80644907, -), ADediting_1215981(80646330, -), ADediting_1215982(80647724, -), ADediting_1215983(80647740, -), ADediting_1215984(80647744, -), ADediting_1215985(80647771, -), ADediting_1581991(80627467, -),

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RNA editing positional annotations for DHFR using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1215889chr5_80626973_-UTR3
ADediting_1215890chr5_80627448_-UTR3
ADediting_1215891chr5_80627451_-UTR3
ADediting_1215892chr5_80627454_-UTR3
ADediting_1215893chr5_80627466_-UTR3
ADediting_1215894chr5_80627470_-UTR3
ADediting_1215895chr5_80627474_-UTR3
ADediting_1215896chr5_80627478_-UTR3
ADediting_1215897chr5_80627484_-UTR3
ADediting_1215898chr5_80627490_-UTR3
ADediting_1215899chr5_80627492_-UTR3
ADediting_1215900chr5_80627502_-UTR3
ADediting_1215901chr5_80627510_-UTR3
ADediting_1215902chr5_80627513_-UTR3
ADediting_1215903chr5_80627514_-UTR3
ADediting_1215904chr5_80627515_-UTR3
ADediting_1215905chr5_80627516_-UTR3
ADediting_1215906chr5_80627517_-UTR3
ADediting_1215907chr5_80627519_-UTR3
ADediting_1215908chr5_80627522_-UTR3
ADediting_1215909chr5_80627523_-UTR3
ADediting_1215910chr5_80627525_-UTR3
ADediting_1215911chr5_80627528_-UTR3
ADediting_1215912chr5_80627534_-UTR3
ADediting_1215913chr5_80627540_-UTR3
ADediting_1215914chr5_80627541_-UTR3
ADediting_1215915chr5_80627542_-UTR3
ADediting_1215916chr5_80627547_-UTR3
ADediting_1215917chr5_80627549_-UTR3
ADediting_1215918chr5_80627559_-UTR3
ADediting_1215919chr5_80627562_-UTR3
ADediting_1215920chr5_80627569_-UTR3
ADediting_1215921chr5_80627574_-UTR3
ADediting_1215922chr5_80627578_-UTR3
ADediting_1215923chr5_80627582_-UTR3
ADediting_1215924chr5_80627583_-UTR3
ADediting_1215925chr5_80627599_-UTR3
ADediting_1215926chr5_80627604_-UTR3
ADediting_1215927chr5_80627605_-UTR3
ADediting_1215928chr5_80627611_-UTR3
ADediting_1215929chr5_80627613_-UTR3
ADediting_1215930chr5_80627627_-UTR3
ADediting_1215931chr5_80627947_-UTR3
ADediting_1215932chr5_80627959_-UTR3
ADediting_1215933chr5_80627960_-UTR3
ADediting_1215934chr5_80627969_-UTR3
ADediting_1215935chr5_80627974_-UTR3
ADediting_1215936chr5_80627982_-UTR3
ADediting_1215937chr5_80628007_-UTR3
ADediting_1215938chr5_80628021_-UTR3
ADediting_1215939chr5_80628024_-UTR3
ADediting_1215940chr5_80628036_-UTR3
ADediting_1215941chr5_80628038_-UTR3
ADediting_1215942chr5_80628041_-UTR3
ADediting_1215943chr5_80628047_-UTR3
ADediting_1215944chr5_80628054_-UTR3
ADediting_1215945chr5_80628076_-UTR3
ADediting_1215946chr5_80628087_-UTR3
ADediting_1215947chr5_80628093_-UTR3
ADediting_1215948chr5_80628097_-UTR3
ADediting_1215949chr5_80628100_-UTR3
ADediting_1215950chr5_80628101_-UTR3
ADediting_1215951chr5_80628126_-UTR3
ADediting_1215952chr5_80628133_-UTR3
ADediting_1215953chr5_80628171_-UTR3
ADediting_1215954chr5_80628176_-UTR3
ADediting_1215955chr5_80628179_-UTR3
ADediting_1215956chr5_80630047_-intronic
ADediting_1215957chr5_80630082_-intronic
ADediting_1215958chr5_80630092_-intronic
ADediting_1215959chr5_80630099_-intronic
ADediting_1215960chr5_80630137_-intronic
ADediting_1215961chr5_80630143_-intronic
ADediting_1215962chr5_80630153_-intronic
ADediting_1215963chr5_80630178_-intronic
ADediting_1215964chr5_80630182_-intronic
ADediting_1215965chr5_80630189_-intronic
ADediting_1215966chr5_80630203_-intronic
ADediting_1215967chr5_80630208_-intronic
ADediting_1215968chr5_80630439_-ncRNA_exonic
ADediting_1215969chr5_80630491_-ncRNA_intronic
ADediting_1215970chr5_80630501_-ncRNA_intronic
ADediting_1215971chr5_80630507_-ncRNA_intronic
ADediting_1215972chr5_80630563_-ncRNA_intronic
ADediting_1215973chr5_80630596_-ncRNA_intronic
ADediting_1215974chr5_80631039_-ncRNA_intronic
ADediting_1215975chr5_80631158_-ncRNA_intronic
ADediting_1215976chr5_80631210_-ncRNA_exonic
ADediting_1215977chr5_80633422_-intronic
ADediting_1215978chr5_80633434_-intronic
ADediting_1215979chr5_80633460_-intronic
ADediting_1215980chr5_80644907_-intronic
ADediting_1215981chr5_80646330_-intronic
ADediting_1215982chr5_80647724_-intronic
ADediting_1215983chr5_80647740_-intronic
ADediting_1215984chr5_80647744_-intronic
ADediting_1215985chr5_80647771_-intronic
ADediting_1581991chr5_80627467_-UTR3

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1215889chr5_80626973_-SINEAluName=FLAM_A
ADediting_1215890chr5_80627448_-SINEAluName=AluJb
ADediting_1215891chr5_80627451_-SINEAluName=AluJb
ADediting_1215892chr5_80627454_-SINEAluName=AluJb
ADediting_1215893chr5_80627466_-SINEAluName=AluJb
ADediting_1215894chr5_80627470_-SINEAluName=AluJb
ADediting_1215895chr5_80627474_-SINEAluName=AluJb
ADediting_1215896chr5_80627478_-SINEAluName=AluJb
ADediting_1215897chr5_80627484_-SINEAluName=AluJb
ADediting_1215898chr5_80627490_-SINEAluName=AluJb
ADediting_1215899chr5_80627492_-SINEAluName=AluJb
ADediting_1215900chr5_80627502_-SINEAluName=AluJb
ADediting_1215901chr5_80627510_-SINEAluName=AluJb
ADediting_1215902chr5_80627513_-SINEAluName=AluJb
ADediting_1215903chr5_80627514_-SINEAluName=AluJb
ADediting_1215904chr5_80627515_-SINEAluName=AluJb
ADediting_1215905chr5_80627516_-SINEAluName=AluJb
ADediting_1215906chr5_80627517_-SINEAluName=AluJb
ADediting_1215907chr5_80627519_-SINEAluName=AluJb
ADediting_1215908chr5_80627522_-SINEAluName=AluJb
ADediting_1215909chr5_80627523_-SINEAluName=AluJb
ADediting_1215910chr5_80627525_-SINEAluName=AluJb
ADediting_1215911chr5_80627528_-SINEAluName=AluJb
ADediting_1215912chr5_80627534_-SINEAluName=AluJb
ADediting_1215913chr5_80627540_-SINEAluName=AluJb
ADediting_1215914chr5_80627541_-SINEAluName=AluJb
ADediting_1215915chr5_80627542_-SINEAluName=AluJb
ADediting_1215916chr5_80627547_-SINEAluName=AluJb
ADediting_1215917chr5_80627549_-SINEAluName=AluJb
ADediting_1215918chr5_80627559_-SINEAluName=AluJb
ADediting_1215919chr5_80627562_-SINEAluName=AluJb
ADediting_1215920chr5_80627569_-SINEAluName=AluJb
ADediting_1215921chr5_80627574_-SINEAluName=AluJb
ADediting_1215922chr5_80627578_-SINEAluName=AluJb
ADediting_1215923chr5_80627582_-SINEAluName=AluJb
ADediting_1215924chr5_80627583_-SINEAluName=AluJb
ADediting_1215925chr5_80627599_-SINEAluName=AluJb
ADediting_1215926chr5_80627604_-SINEAluName=AluJb
ADediting_1215927chr5_80627605_-SINEAluName=AluJb
ADediting_1215928chr5_80627611_-SINEAluName=AluJb
ADediting_1215929chr5_80627613_-SINEAluName=AluJb
ADediting_1215930chr5_80627627_-SINEAluName=AluJb
ADediting_1215931chr5_80627947_-SINEAluName=AluSq2
ADediting_1215932chr5_80627959_-SINEAluName=AluSq2
ADediting_1215933chr5_80627960_-SINEAluName=AluSq2
ADediting_1215934chr5_80627969_-SINEAluName=AluSq2
ADediting_1215935chr5_80627974_-SINEAluName=AluSq2
ADediting_1215936chr5_80627982_-SINEAluName=AluSq2
ADediting_1215937chr5_80628007_-SINEAluName=AluSq2
ADediting_1215938chr5_80628021_-SINEAluName=AluSq2
ADediting_1215939chr5_80628024_-SINEAluName=AluSq2
ADediting_1215940chr5_80628036_-SINEAluName=AluSq2
ADediting_1215941chr5_80628038_-SINEAluName=AluSq2
ADediting_1215942chr5_80628041_-SINEAluName=AluSq2
ADediting_1215943chr5_80628047_-SINEAluName=AluSq2
ADediting_1215944chr5_80628054_-SINEAluName=AluSq2
ADediting_1215945chr5_80628076_-SINEAluName=AluSq2
ADediting_1215946chr5_80628087_-SINEAluName=AluSq2
ADediting_1215947chr5_80628093_-SINEAluName=AluSq2
ADediting_1215948chr5_80628097_-SINEAluName=AluSq2
ADediting_1215949chr5_80628100_-SINEAluName=AluSq2
ADediting_1215950chr5_80628101_-SINEAluName=AluSq2
ADediting_1215951chr5_80628126_-SINEAluName=AluSq2
ADediting_1215952chr5_80628133_-SINEAluName=AluSq2
ADediting_1215953chr5_80628171_-SINEAluName=AluSq2
ADediting_1215954chr5_80628176_-SINEAluName=AluSq2
ADediting_1215955chr5_80628179_-SINEAluName=AluSq2
ADediting_1215956chr5_80630047_-SINEAluName=AluSx1
ADediting_1215957chr5_80630082_-SINEAluName=AluSx1
ADediting_1215958chr5_80630092_-SINEAluName=AluSx1
ADediting_1215959chr5_80630099_-SINEAluName=AluSx1
ADediting_1215960chr5_80630137_-SINEAluName=AluSx1
ADediting_1215961chr5_80630143_-SINEAluName=AluSx1
ADediting_1215962chr5_80630153_-SINEAluName=AluSx1
ADediting_1215963chr5_80630178_-SINEAluName=AluSx1
ADediting_1215964chr5_80630182_-SINEAluName=AluSx1
ADediting_1215965chr5_80630189_-SINEAluName=AluSx1
ADediting_1215966chr5_80630203_-SINEAluName=AluSx1
ADediting_1215967chr5_80630208_-SINEAluName=AluSx1
ADediting_1215968chr5_80630439_-SINEAluName=AluY
ADediting_1215969chr5_80630491_-SINEAluName=AluY
ADediting_1215970chr5_80630501_-SINEAluName=AluY
ADediting_1215971chr5_80630507_-SINEAluName=AluY
ADediting_1215972chr5_80630563_-SINEAluName=AluY
ADediting_1215973chr5_80630596_-SINEAluName=AluY
ADediting_1215974chr5_80631039_-SINEAluName=AluSx
ADediting_1215975chr5_80631158_-SINEAluName=AluSx
ADediting_1215976chr5_80631210_-SINEAluName=AluSx
ADediting_1215977chr5_80633422_-SINEAluName=AluSx
ADediting_1215978chr5_80633434_-SINEAluName=AluSx
ADediting_1215979chr5_80633460_-SINEAluName=AluSx
ADediting_1215980chr5_80644907_-SINEAluName=AluSx
ADediting_1215981chr5_80646330_-SINEAluName=AluSx1
ADediting_1215982chr5_80647724_-SINEAluName=AluJb
ADediting_1215983chr5_80647740_-SINEAluName=AluJb
ADediting_1215984chr5_80647744_-SINEAluName=AluJb
ADediting_1215985chr5_80647771_-SINEAluName=AluJb
ADediting_1581991chr5_80627467_-SINEAluName=AluJb

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RNA A-to-I editing events in the alternative splicing sites for DHFR

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for DHFR

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.
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check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for DHFR

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for DHFR

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1215891chr5_80627451_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-1236-3pchr580627451806274577mer-m88062745080627471153-17.17
ADediting_1215892chr5_80627454_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4691-5pchr580627451806274588mer-1a8062745180627470144-18.21
ADediting_1215892chr5_80627454_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6792-3pchr580627451806274588mer-1a8062745180627477152-22.87
ADediting_1215893chr5_80627466_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-660-3pchr580627465806274717mer-m88062746480627484157-19.68
ADediting_1215893chr5_80627466_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6791-3pchr580627464806274707mer-m88062746380627483140-15.2
ADediting_1215893chr5_80627466_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6829-3pchr580627464806274707mer-m88062746380627482142-15.25
ADediting_1215896chr5_80627478_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-483-5pchr580627474806274818mer-1a8062747480627495156-21.28
ADediting_1215897chr5_80627484_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-1292-5pchr580627478806274847mer-1a8062747880627506140-22.45
ADediting_1215897chr5_80627484_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6768-5pchr580627483806274897mer-m88062748280627504140-18.04
ADediting_1215899chr5_80627492_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4783-5pchr580627490806274978mer-1a8062749080627511157-30.23
ADediting_1215903chr5_80627514_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6844chr580627513806275197mer-m88062751280627532152-7.3
ADediting_1215904chr5_80627515_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-578chr580627513806275197mer-m88062751280627532149-9.96
ADediting_1215904chr5_80627515_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-581chr580627514806275218mer-1a8062751480627536151-13.05
ADediting_1215908chr5_80627522_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4711-3pchr580627517806275248mer-1a8062751780627534147-11.7
ADediting_1215908chr5_80627522_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-511-5pchr580627519806275257mer-m88062751880627538150-15.22
ADediting_1215909chr5_80627523_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4677-5pchr580627519806275257mer-m88062751880627539150-10.9
ADediting_1215909chr5_80627523_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6844chr580627521806275288mer-1a8062752180627541140-8.12
ADediting_1215911chr5_80627528_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3678-3pchr580627525806275328mer-1a8062752580627546144-14.46
ADediting_1215911chr5_80627528_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4756-3pchr580627528806275347mer-m88062752780627547158-20.59
ADediting_1215911chr5_80627528_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-557chr580627523806275297mer-1a8062752380627545147-23.4
ADediting_1215912chr5_80627534_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4508chr580627534806275407mer-m88062753380627549144-23.33
ADediting_1215912chr5_80627534_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-483-5pchr580627531806275377mer-m88062753080627551140-14
ADediting_1215914chr5_80627541_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3194-3pchr580627538806275447mer-m88062753780627565148-24.88
ADediting_1215914chr5_80627541_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4727-5pchr580627540806275467mer-m88062753980627559154-17.39
ADediting_1215914chr5_80627541_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4769-3pchr580627540806275478mer-1a8062754080627561148-17.5
ADediting_1215914chr5_80627541_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6817-5pchr580627540806275478mer-1a8062754080627560141-18.02
ADediting_1215914chr5_80627541_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-760chr580627537806275437mer-m88062753680627554143-16.3
ADediting_1215916chr5_80627547_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-12121chr580627541806275488mer-1a8062754180627560145-20.68
ADediting_1215919chr5_80627562_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3176chr580627558806275647mer-m88062755780627579143-17.75
ADediting_1215919chr5_80627562_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3922-3pchr580627558806275647mer-m88062755780627576156-17.39
ADediting_1215919chr5_80627562_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6878-3pchr580627559806275657mer-m88062755880627580145-23.52
ADediting_1215921chr5_80627574_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4485-5pchr580627572806275798mer-1a8062757280627587150-21.76
ADediting_1215922chr5_80627578_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4707-3pchr580627574806275818mer-1a8062757480627595154-24.16
ADediting_1215923chr5_80627582_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-18a-3pchr580627577806275837mer-m88062757680627596154-24.38
ADediting_1215923chr5_80627582_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3157-3pchr580627578806275847mer-m88062757780627597166-31.5
ADediting_1215925chr5_80627599_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3195chr580627595806276017mer-m88062759480627610145-22.63
ADediting_1215927chr5_80627605_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-513a-5pchr580627604806276107mer-m88062760380627620144-17.77
ADediting_1215927chr5_80627605_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-638chr580627599806276057mer-1a8062759980627623149-29.88
ADediting_1215932chr5_80627959_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3189-3pchr580627958806279647mer-m88062795780627980157-25.36
ADediting_1215932chr5_80627959_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6813-3pchr580627957806279637mer-m88062795680627976140-10.68
ADediting_1215933chr5_80627960_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-326chr580627958806279647mer-m88062795780627976140-13.25
ADediting_1215933chr5_80627960_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-330-5pchr580627958806279647mer-m88062795780627980141-19.11
ADediting_1215933chr5_80627960_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4314chr580627959806279657mer-m88062795880627976141-20.85
ADediting_1215933chr5_80627960_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-514a-5pchr580627957806279637mer-m88062795680627979150-18.62
ADediting_1215934chr5_80627969_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6089chr580627964806279707mer-m88062796380627986171-43.73
ADediting_1215935chr5_80627974_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6765-5pchr580627969806279757mer-m88062796880627992150-26.44
ADediting_1215937chr5_80628007_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4786-5pchr580628002806280087mer-m88062800180628026152-25.28
ADediting_1215937chr5_80628007_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6849-3pchr580628006806280127mer-m88062800580628025152-21.45
ADediting_1215938chr5_80628021_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-433-5pchr580628020806280267mer-m88062801980628042159-23.87
ADediting_1215938chr5_80628021_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-433-5pchr580628020806280267mer-m88062801980628042159-23.87
ADediting_1215945chr5_80628076_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-10400-5pchr580628073806280808mer-1a8062807380628092156-28.68
ADediting_1215945chr5_80628076_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4467chr580628073806280808mer-1a8062807380628095145-25.94
ADediting_1215945chr5_80628076_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6770-3pchr580628073806280797mer-m88062807280628093150-20.76
ADediting_1215945chr5_80628076_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-10400-5pchr580628073806280808mer-1a8062807380628092156-28.68
ADediting_1215945chr5_80628076_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-4467chr580628073806280808mer-1a8062807380628095145-25.94
ADediting_1215945chr5_80628076_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-6770-3pchr580628073806280797mer-m88062807280628093150-20.76
ADediting_1215947chr5_80628093_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-5690chr580628093806280997mer-m88062809280628112145-16.74
ADediting_1215947chr5_80628093_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-7977chr580628090806280967mer-m88062808980628106142-12.24
ADediting_1215947chr5_80628093_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-5690chr580628093806280997mer-m88062809280628112145-16.74
ADediting_1215947chr5_80628093_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-7977chr580628090806280967mer-m88062808980628106142-12.24
ADediting_1215948chr5_80628097_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3614-5pchr580628097806281037mer-m88062809680628119156-27.22
ADediting_1215948chr5_80628097_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-3614-5pchr580628097806281037mer-m88062809680628119156-27.22
ADediting_1215950chr5_80628101_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6771-5pchr580628100806281067mer-m88062809980628118157-30.52
ADediting_1215950chr5_80628101_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-6771-5pchr580628100806281067mer-m88062809980628118157-30.52
ADediting_1215951chr5_80628126_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3140-5pchr580628125806281317mer-m88062812480628144146-10.22
ADediting_1215951chr5_80628126_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-5187-3pchr580628126806281327mer-m88062812580628145140-8.85
ADediting_1215951chr5_80628126_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6078chr580628122806281298mer-1a8062812280628141144-20.72
ADediting_1215951chr5_80628126_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-3140-5pchr580628125806281317mer-m88062812480628144146-10.22
ADediting_1215951chr5_80628126_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-5187-3pchr580628126806281327mer-m88062812580628145140-8.85
ADediting_1215951chr5_80628126_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-6078chr580628122806281298mer-1a8062812280628141144-20.72
ADediting_1215951chr5_80628126_-ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-3140-5pchr580628125806281317mer-m88062812480628144146-10.22
ADediting_1215951chr5_80628126_-ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-5187-3pchr580628126806281327mer-m88062812580628145140-8.85
ADediting_1215952chr5_80628133_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4497chr580628131806281377mer-m88062813080628146155-23.26
ADediting_1215952chr5_80628133_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-4497chr580628131806281377mer-m88062813080628146155-23.26
ADediting_1215952chr5_80628133_-ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-4497chr580628131806281377mer-m88062813080628146155-23.26
ADediting_1215953chr5_80628171_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-217-5pchr580628170806281767mer-m88062816980628191142-16.29
ADediting_1215953chr5_80628171_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-324-3pchr580628168806281747mer-m88062816780628189140-22.55
ADediting_1215953chr5_80628171_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6807-3pchr580628170806281767mer-m88062816980628191164-24.94
ADediting_1215953chr5_80628171_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-217-5pchr580628170806281767mer-m88062816980628191142-16.29
ADediting_1215953chr5_80628171_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-324-3pchr580628168806281747mer-m88062816780628189140-22.55
ADediting_1215953chr5_80628171_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-6807-3pchr580628170806281767mer-m88062816980628191164-24.94
ADediting_1215953chr5_80628171_-ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-217-5pchr580628170806281767mer-m88062816980628191142-16.29
ADediting_1215953chr5_80628171_-ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-324-3pchr580628168806281747mer-m88062816780628189140-22.55
ADediting_1215953chr5_80628171_-ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-6807-3pchr580628170806281767mer-m88062816980628191164-24.94
ADediting_1215955chr5_80628179_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-1202chr580628176806281827mer-m88062817580628198154-25.99
ADediting_1215955chr5_80628179_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3194-5pchr580628176806281838mer-1a8062817680628199146-23.03
ADediting_1215955chr5_80628179_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3972chr580628176806281827mer-m88062817580628197147-20.7
ADediting_1215955chr5_80628179_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6849-3pchr580628178806281847mer-m88062817780628197150-17.04
ADediting_1215955chr5_80628179_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-1202chr580628176806281827mer-m88062817580628198154-25.99
ADediting_1215955chr5_80628179_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-3194-5pchr580628176806281838mer-1a8062817680628199146-23.03
ADediting_1215955chr5_80628179_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-3972chr580628176806281827mer-m88062817580628197147-20.7
ADediting_1215955chr5_80628179_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-6849-3pchr580628178806281847mer-m88062817780628197150-17.04
ADediting_1215955chr5_80628179_-ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-1202chr580628176806281827mer-m88062817580628198154-25.99
ADediting_1215955chr5_80628179_-ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-3194-5pchr580628176806281838mer-1a8062817680628199146-23.03
ADediting_1215955chr5_80628179_-ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-3972chr580628176806281827mer-m88062817580628197147-20.7
ADediting_1215955chr5_80628179_-ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-6849-3pchr580628178806281847mer-m88062817780628197150-17.04
ADediting_1581991chr5_80627467_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4732-3pchr580627466806274738mer-1a8062746680627486140-14.2
ADediting_1581991chr5_80627467_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-670-5pchr580627466806274727mer-m88062746580627484158-20.05
ADediting_1581991chr5_80627467_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6736-3pchr580627461806274688mer-1a8062746180627482145-16.92
ADediting_1581991chr5_80627467_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-7106-3pchr580627464806274707mer-m88062746380627485153-19.91
ADediting_1581991chr5_80627467_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-7113-3pchr580627465806274717mer-m88062746480627486142-13.3

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1215889chr5_80626973_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3663-5pchr580626972806269787mer-m88062697180626995148-28.59
ADediting_1215889chr5_80626973_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6131chr580626971806269777mer-m88062697080626985144-21.2
ADediting_1215891chr5_80627451_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6875-3pchr580627451806274577mer-m88062745080627471152-19.05
ADediting_1215892chr5_80627454_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6875-3pchr580627451806274577mer-m88062745080627471152-19.05
ADediting_1215893chr5_80627466_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-516a-3pchr580627464806274707mer-m88062746380627481147-18.9
ADediting_1215893chr5_80627466_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-516b-3pchr580627464806274707mer-m88062746380627481147-18.9
ADediting_1215893chr5_80627466_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-7162-5pchr580627464806274707mer-m88062746380627479145-13.78
ADediting_1215894chr5_80627470_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-378a-5pchr580627466806274738mer-1a8062746680627485148-14.38
ADediting_1215895chr5_80627474_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-28-3pchr580627472806274787mer-m88062747180627492145-12.79
ADediting_1215898chr5_80627490_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3934-5pchr580627486806274927mer-m88062748580627506149-20.36
ADediting_1215898chr5_80627490_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-552-3pchr580627484806274918mer-1a8062748480627503142-13.19
ADediting_1215900chr5_80627502_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-365a-3pchr580627500806275067mer-m88062749980627522147-13.55
ADediting_1215900chr5_80627502_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-365b-3pchr580627500806275067mer-m88062749980627522147-13.55
ADediting_1215901chr5_80627510_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4735-5pchr580627509806275157mer-m88062750880627529140-4.7
ADediting_1215902chr5_80627513_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4735-5pchr580627509806275157mer-m88062750880627529140-4.7
ADediting_1215903chr5_80627514_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4735-5pchr580627509806275157mer-m88062750880627529140-4.7
ADediting_1215904chr5_80627515_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-5010-3pchr580627514806275218mer-1a8062751480627535142-7.96
ADediting_1215905chr5_80627516_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-5010-3pchr580627514806275218mer-1a8062751480627535142-7.96
ADediting_1215906chr5_80627517_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-5010-3pchr580627514806275218mer-1a8062751480627535142-7.96
ADediting_1215907chr5_80627519_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-5010-3pchr580627514806275218mer-1a8062751480627535142-7.96
ADediting_1215910chr5_80627525_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3674chr580627524806275318mer-1a8062752480627545140-10.26
ADediting_1215911chr5_80627528_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3674chr580627524806275318mer-1a8062752480627545140-10.26
ADediting_1215911chr5_80627528_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6832-5pchr580627526806275338mer-1a8062752680627548142-13.77
ADediting_1215912chr5_80627534_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3675-5pchr580627533806275397mer-m88062753280627553154-16.67
ADediting_1215913chr5_80627540_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-1251-3pchr580627538806275447mer-m88062753780627557141-12.99
ADediting_1215914chr5_80627541_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-1251-3pchr580627538806275447mer-m88062753780627557141-12.99
ADediting_1215914chr5_80627541_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4776-3pchr580627540806275478mer-1a8062754080627563155-18.04
ADediting_1215915chr5_80627542_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-1251-3pchr580627538806275447mer-m88062753780627557141-12.99
ADediting_1215915chr5_80627542_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4659a-5pchr580627541806275488mer-1a8062754180627565149-16.42
ADediting_1215915chr5_80627542_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4659b-5pchr580627541806275488mer-1a8062754180627562149-18.53
ADediting_1215915chr5_80627542_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4776-3pchr580627540806275478mer-1a8062754080627563155-18.04
ADediting_1215916chr5_80627547_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4659a-5pchr580627541806275488mer-1a8062754180627565149-16.42
ADediting_1215916chr5_80627547_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4659b-5pchr580627541806275488mer-1a8062754180627562149-18.53
ADediting_1215916chr5_80627547_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4716-5pchr580627544806275507mer-m88062754380627564148-13.48
ADediting_1215916chr5_80627547_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-744-3pchr580627547806275537mer-m88062754680627570149-14.59
ADediting_1215917chr5_80627549_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4716-5pchr580627544806275507mer-m88062754380627564148-13.48
ADediting_1215917chr5_80627549_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-744-3pchr580627547806275537mer-m88062754680627570149-14.59
ADediting_1215918chr5_80627559_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-320echr580627555806275617mer-m88062755480627571146-12.92
ADediting_1215918chr5_80627559_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3663-5pchr580627558806275647mer-m88062755780627577151-21.84
ADediting_1215918chr5_80627559_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6131chr580627557806275637mer-m88062755680627574148-16.73
ADediting_1215918chr5_80627559_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6848-3pchr580627559806275657mer-m88062755880627576140-13.16
ADediting_1215919chr5_80627562_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3663-5pchr580627558806275647mer-m88062755780627577151-21.84
ADediting_1215919chr5_80627562_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-513c-5pchr580627562806275687mer-m88062756180627584154-19.19
ADediting_1215919chr5_80627562_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-514b-5pchr580627562806275687mer-m88062756180627582144-14.09
ADediting_1215919chr5_80627562_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6131chr580627557806275637mer-m88062755680627574148-16.73
ADediting_1215919chr5_80627562_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6848-3pchr580627559806275657mer-m88062755880627576140-13.16
ADediting_1215920chr5_80627569_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-1245achr580627567806275737mer-m88062756680627586153-19.32
ADediting_1215920chr5_80627569_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-8079chr580627567806275737mer-m88062756680627584155-17.84
ADediting_1215921chr5_80627574_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-5001-3pchr580627572806275787mer-m88062757180627590144-17.41
ADediting_1215922chr5_80627578_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6747-3pchr580627576806275827mer-m88062757580627596154-22.42
ADediting_1215925chr5_80627599_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-5089-5pchr580627599806276057mer-m88062759880627620148-13.62
ADediting_1215925chr5_80627599_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6506-5pchr580627598806276047mer-m88062759780627619144-13.21
ADediting_1215926chr5_80627604_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-10399-5pchr580627603806276097mer-m88062760280627623148-10
ADediting_1215926chr5_80627604_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-5089-5pchr580627599806276057mer-m88062759880627620148-13.62
ADediting_1215926chr5_80627604_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6504-3pchr580627603806276097mer-m88062760280627623149-15.11
ADediting_1215927chr5_80627605_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-10399-5pchr580627603806276097mer-m88062760280627623148-10
ADediting_1215927chr5_80627605_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6504-3pchr580627603806276097mer-m88062760280627623149-15.11
ADediting_1215928chr5_80627611_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-552-3pchr580627605806276128mer-1a8062760580627625140-14.1
ADediting_1215929chr5_80627613_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6807-5pchr580627613806276197mer-m88062761280627634152-27.29
ADediting_1215930chr5_80627627_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-1271-3pchr580627621806276288mer-1a8062762180627642142-15.31
ADediting_1215930chr5_80627627_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3064-5pchr580627626806276327mer-m88062762580627645144-14.07
ADediting_1215930chr5_80627627_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3085-3pchr580627626806276327mer-m88062762580627645144-14.34
ADediting_1215930chr5_80627627_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-550a-3-5pchr580627621806276288mer-1a8062762180627640140-15.46
ADediting_1215930chr5_80627627_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-550a-5pchr580627621806276288mer-1a8062762180627643140-16.78
ADediting_1215930chr5_80627627_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6504-5pchr580627626806276327mer-m88062762580627645140-16.75
ADediting_1215930chr5_80627627_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6842-3pchr580627627806276337mer-m88062762680627646150-19.37
ADediting_1215933chr5_80627960_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-887-5pchr580627959806279668mer-1a8062795980627978143-13.53
ADediting_1215934chr5_80627969_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4478chr580627965806279717mer-m88062796480627980154-23.41
ADediting_1215934chr5_80627969_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-7160-5pchr580627967806279737mer-m88062796680627983148-19.26
ADediting_1215934chr5_80627969_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-7162-3pchr580627968806279747mer-m88062796780627985150-18.21
ADediting_1215935chr5_80627974_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-1262chr580627974806279807mer-m88062797380627994152-18.19
ADediting_1215935chr5_80627974_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4701-3pchr580627974806279807mer-m88062797380627994153-22.2
ADediting_1215935chr5_80627974_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6134chr580627969806279768mer-1a8062796980627987150-17.77
ADediting_1215935chr5_80627974_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6736-5pchr580627974806279807mer-m88062797380627992145-22.19
ADediting_1215935chr5_80627974_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6748-5pchr580627973806279797mer-m88062797280627993142-19.3
ADediting_1215935chr5_80627974_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6769a-5pchr580627972806279787mer-m88062797180627991140-19.6
ADediting_1215935chr5_80627974_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6769b-5pchr580627972806279787mer-m88062797180627993147-21.53
ADediting_1215940chr5_80628036_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3675-3pchr580628033806280397mer-m88062803280628053145-12.58
ADediting_1215940chr5_80628036_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-3675-3pchr580628033806280397mer-m88062803280628053145-12.58
ADediting_1215941chr5_80628038_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3675-3pchr580628033806280397mer-m88062803280628053145-12.58
ADediting_1215941chr5_80628038_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-3675-3pchr580628033806280397mer-m88062803280628053145-12.58
ADediting_1215946chr5_80628087_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6765-3pchr580628083806280897mer-m88062808280628104148-19.15
ADediting_1215946chr5_80628087_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-6804-3pchr580628082806280887mer-m88062808180628101150-19.78
ADediting_1215946chr5_80628087_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-7152-3pchr580628086806280927mer-m88062808580628108152-26.99
ADediting_1215946chr5_80628087_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-6765-3pchr580628083806280897mer-m88062808280628104148-19.15
ADediting_1215946chr5_80628087_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-6804-3pchr580628082806280887mer-m88062808180628101150-19.78
ADediting_1215946chr5_80628087_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-7152-3pchr580628086806280927mer-m88062808580628108152-26.99
ADediting_1215949chr5_80628100_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-12126chr580628097806281048mer-1a8062809780628120155-17.04
ADediting_1215949chr5_80628100_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-887-5pchr580628100806281067mer-m88062809980628118151-24.36
ADediting_1215949chr5_80628100_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-12126chr580628097806281048mer-1a8062809780628120155-17.04
ADediting_1215949chr5_80628100_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-887-5pchr580628100806281067mer-m88062809980628118151-24.36
ADediting_1215950chr5_80628101_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-12126chr580628097806281048mer-1a8062809780628120155-17.04
ADediting_1215950chr5_80628101_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-887-5pchr580628100806281067mer-m88062809980628118151-24.36
ADediting_1215950chr5_80628101_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-12126chr580628097806281048mer-1a8062809780628120155-17.04
ADediting_1215950chr5_80628101_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-887-5pchr580628100806281067mer-m88062809980628118151-24.36
ADediting_1215952chr5_80628133_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-1298-3pchr580628130806281367mer-m88062812980628149142-11.38
ADediting_1215952chr5_80628133_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3192-5pchr580628131806281377mer-1a8062813180628157140-25.29
ADediting_1215952chr5_80628133_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4314chr580628131806281377mer-m88062813080628147151-17.05
ADediting_1215952chr5_80628133_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-4646-5pchr580628131806281388mer-1a8062813180628153155-23.8
ADediting_1215952chr5_80628133_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-1298-3pchr580628130806281367mer-m88062812980628149142-11.38
ADediting_1215952chr5_80628133_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-3192-5pchr580628131806281377mer-1a8062813180628157140-25.29
ADediting_1215952chr5_80628133_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-4314chr580628131806281377mer-m88062813080628147151-17.05
ADediting_1215952chr5_80628133_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-4646-5pchr580628131806281388mer-1a8062813180628153155-23.8
ADediting_1215952chr5_80628133_-ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-1298-3pchr580628130806281367mer-m88062812980628149142-11.38
ADediting_1215952chr5_80628133_-ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-3192-5pchr580628131806281377mer-1a8062813180628157140-25.29
ADediting_1215952chr5_80628133_-ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-4314chr580628131806281377mer-m88062813080628147151-17.05
ADediting_1215952chr5_80628133_-ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-4646-5pchr580628131806281388mer-1a8062813180628153155-23.8
ADediting_1215954chr5_80628176_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3146chr580628175806281817mer-m88062817480628196146-14.6
ADediting_1215954chr5_80628176_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-3146chr580628175806281817mer-m88062817480628196146-14.6
ADediting_1215954chr5_80628176_-ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-3146chr580628175806281817mer-m88062817480628196146-14.6
ADediting_1215955chr5_80628179_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-3146chr580628175806281817mer-m88062817480628196146-14.6
ADediting_1215955chr5_80628179_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-3146chr580628175806281817mer-m88062817480628196146-14.6
ADediting_1215955chr5_80628179_-ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-3146chr580628175806281817mer-m88062817480628196146-14.6
ADediting_1581991chr5_80627467_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-378a-5pchr580627466806274738mer-1a8062746680627485148-14.38
ADediting_1581991chr5_80627467_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-516a-3pchr580627464806274707mer-m88062746380627481147-18.9
ADediting_1581991chr5_80627467_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-516b-3pchr580627464806274707mer-m88062746380627481147-18.9
ADediting_1581991chr5_80627467_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-7162-5pchr580627464806274707mer-m88062746380627479145-13.78

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-589-3pchr580626543806265497mer-m88062654280626564152-15.47
ADediting_1535951chr14_100874558_+ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-337-3pchr580626802806268087mer-m88062680180626819151-16.12
ADediting_1535954chr14_101045974_+ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-381-3pchr580627483806274897mer-m88062748280627503144-13.12
ADediting_1596844chr1_162342605_+ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-556-3pchr580627111806271177mer-m88062711080627134143-12.07
ADediting_291761chr11_93733708_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-1304-3pchr580628460806284667mer-m88062845980628478143-12.77
ADediting_291761chr11_93733708_-ENSG00000228716.7ENST00000504396.1DHFR-202hsa-miR-1304-3pchr580628460806284667mer-m88062845980628478143-12.77
ADediting_291761chr11_93733708_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-1304-3pchr580628460806284667mer-m88062845980628478143-12.77
ADediting_291761chr11_93733708_-ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-1304-3pchr580628460806284667mer-m88062845980628478143-12.77

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337758chr7_5495892_-ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-589-5pchr580628450806284578mer-1a8062845080628470147-19.48
ADediting_1337758chr7_5495892_-ENSG00000228716.7ENST00000504396.1DHFR-202hsa-miR-589-5pchr580628450806284578mer-1a8062845080628470147-19.48
ADediting_1337758chr7_5495892_-ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-589-5pchr580628450806284578mer-1a8062845080628470147-19.48
ADediting_1337758chr7_5495892_-ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-589-5pchr580628450806284578mer-1a8062845080628470147-19.48
ADediting_1596844chr1_162342605_+ENSG00000228716.7ENST00000439211.7DHFR-201hsa-miR-556-3pchr580628782806287887mer-m88062878180628802149-10.2
ADediting_1596844chr1_162342605_+ENSG00000228716.7ENST00000504396.1DHFR-202hsa-miR-556-3pchr580628782806287887mer-m88062878180628802149-10.2
ADediting_1596844chr1_162342605_+ENSG00000228716.7ENST00000505337.5DHFR-203hsa-miR-556-3pchr580628782806287887mer-m88062878180628802149-10.2
ADediting_1596844chr1_162342605_+ENSG00000228716.7ENST00000511032.5DHFR-205hsa-miR-556-3pchr580628782806287887mer-m88062878180628802149-10.2

check button Differentially expressed gene-miRNA network
Differentially expressed mRNA-miRNA network
boxplot

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The effects of the RNA editing to the stability of the RNA structures for DHFR

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000439211.7protein_codingSoverviewSoverview
ENST00000505337.5protein_codingSoverviewSoverview
ENST00000511032.5protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_1215889ENST00000439211.7chr5_80626973_-3172-1294.00-1293.50-1385.30
ADediting_1215890ENST00000439211.7chr5_80627448_-2697-1294.80-1293.50-1385.30
ADediting_1215891ENST00000439211.7chr5_80627451_-2694-1293.50-1293.50-1385.30
ADediting_1215892ENST00000439211.7chr5_80627454_-2691-1294.50-1293.50-1385.30
ADediting_1215893ENST00000439211.7chr5_80627466_-2679-1297.80-1293.50-1385.30
ADediting_1581991ENST00000439211.7chr5_80627467_-2678-1296.90-1293.50-1385.30
ADediting_1215894ENST00000439211.7chr5_80627470_-2675-1296.70-1293.50-1385.30
ADediting_1215895ENST00000439211.7chr5_80627474_-2671-1293.50-1293.50-1385.30
ADediting_1215896ENST00000439211.7chr5_80627478_-2667-1293.10-1293.50-1385.30
ADediting_1215897ENST00000439211.7chr5_80627484_-2661-1294.20-1293.50-1385.30
ADediting_1215898ENST00000439211.7chr5_80627490_-2655-1293.10-1293.50-1385.30
ADediting_1215899ENST00000439211.7chr5_80627492_-2653-1298.90-1293.50-1385.30
ADediting_1215900ENST00000439211.7chr5_80627502_-2643-1298.90-1293.50-1385.30
ADediting_1215901ENST00000439211.7chr5_80627510_-2635-1293.20-1293.50-1385.30
ADediting_1215902ENST00000439211.7chr5_80627513_-2632-1293.50-1293.50-1385.30
ADediting_1215903ENST00000439211.7chr5_80627514_-2631-1293.60-1293.50-1385.30
ADediting_1215904ENST00000439211.7chr5_80627515_-2630-1293.60-1293.50-1385.30
ADediting_1215905ENST00000439211.7chr5_80627516_-2629-1293.60-1293.50-1385.30
ADediting_1215906ENST00000439211.7chr5_80627517_-2628-1293.20-1293.50-1385.30
ADediting_1215907ENST00000439211.7chr5_80627519_-2626-1293.80-1293.50-1385.30
ADediting_1215908ENST00000439211.7chr5_80627522_-2623-1293.60-1293.50-1385.30
ADediting_1215909ENST00000439211.7chr5_80627523_-2622-1293.60-1293.50-1385.30
ADediting_1215910ENST00000439211.7chr5_80627525_-2620-1293.60-1293.50-1385.30
ADediting_1215911ENST00000439211.7chr5_80627528_-2617-1293.50-1293.50-1385.30
ADediting_1215912ENST00000439211.7chr5_80627534_-2611-1293.10-1293.50-1385.30
ADediting_1215913ENST00000439211.7chr5_80627540_-2605-1293.10-1293.50-1385.30
ADediting_1215914ENST00000439211.7chr5_80627541_-2604-1293.40-1293.50-1385.30
ADediting_1215915ENST00000439211.7chr5_80627542_-2603-1297.70-1293.50-1385.30
ADediting_1215916ENST00000439211.7chr5_80627547_-2598-1293.10-1293.50-1385.30
ADediting_1215917ENST00000439211.7chr5_80627549_-2596-1293.50-1293.50-1385.30
ADediting_1215918ENST00000439211.7chr5_80627559_-2586-1293.50-1293.50-1385.30
ADediting_1215919ENST00000439211.7chr5_80627562_-2583-1292.90-1293.50-1385.30
ADediting_1215920ENST00000439211.7chr5_80627569_-2576-1298.60-1293.50-1385.30
ADediting_1215921ENST00000439211.7chr5_80627574_-2571-1298.10-1293.50-1385.30
ADediting_1215922ENST00000439211.7chr5_80627578_-2567-1298.20-1293.50-1385.30
ADediting_1215923ENST00000439211.7chr5_80627582_-2563-1294.70-1293.50-1385.30
ADediting_1215924ENST00000439211.7chr5_80627583_-2562-1299.90-1293.50-1385.30
ADediting_1215925ENST00000439211.7chr5_80627599_-2546-1292.80-1293.50-1385.30
ADediting_1215926ENST00000439211.7chr5_80627604_-2541-1293.50-1293.50-1385.30
ADediting_1215927ENST00000439211.7chr5_80627605_-2540-1293.60-1293.50-1385.30
ADediting_1215928ENST00000439211.7chr5_80627611_-2534-1297.40-1293.50-1385.30
ADediting_1215929ENST00000439211.7chr5_80627613_-2532-1292.30-1293.50-1385.30
ADediting_1215930ENST00000439211.7chr5_80627627_-2518-1299.70-1293.50-1385.30
ADediting_1215931ENST00000439211.7chr5_80627947_-2198-1293.50-1293.50-1385.30
ADediting_1215932ENST00000439211.7chr5_80627959_-2186-1293.20-1293.50-1385.30
ADediting_1215933ENST00000439211.7chr5_80627960_-2185-1293.60-1293.50-1385.30
ADediting_1215934ENST00000439211.7chr5_80627969_-2176-1293.50-1293.50-1385.30
ADediting_1215935ENST00000439211.7chr5_80627974_-2171-1297.40-1293.50-1385.30
ADediting_1215936ENST00000439211.7chr5_80627982_-2163-1296.10-1293.50-1385.30
ADediting_1215937ENST00000439211.7chr5_80628007_-2138-1300.10-1293.50-1385.30
ADediting_1215938ENST00000439211.7chr5_80628021_-2124-1293.10-1293.50-1385.30
ADediting_1215939ENST00000439211.7chr5_80628024_-2121-1297.10-1293.50-1385.30
ADediting_1215940ENST00000439211.7chr5_80628036_-2109-1292.60-1293.50-1385.30
ADediting_1215941ENST00000439211.7chr5_80628038_-2107-1293.20-1293.50-1385.30
ADediting_1215942ENST00000439211.7chr5_80628041_-2104-1293.50-1293.50-1385.30
ADediting_1215943ENST00000439211.7chr5_80628047_-2098-1297.00-1293.50-1385.30
ADediting_1215944ENST00000439211.7chr5_80628054_-2091-1298.50-1293.50-1385.30
ADediting_1215945ENST00000439211.7chr5_80628076_-2069-1293.10-1293.50-1385.30
ADediting_1215946ENST00000439211.7chr5_80628087_-2058-1292.80-1293.50-1385.30
ADediting_1215947ENST00000439211.7chr5_80628093_-2052-1300.10-1293.50-1385.30
ADediting_1215948ENST00000439211.7chr5_80628097_-2048-1293.80-1293.50-1385.30
ADediting_1215949ENST00000439211.7chr5_80628100_-2045-1293.10-1293.50-1385.30
ADediting_1215950ENST00000439211.7chr5_80628101_-2044-1296.90-1293.50-1385.30
ADediting_1215951ENST00000439211.7chr5_80628126_-2019-1295.90-1293.50-1385.30
ADediting_1215952ENST00000439211.7chr5_80628133_-2012-1296.70-1293.50-1385.30
ADediting_1215953ENST00000439211.7chr5_80628171_-1974-1299.30-1293.50-1385.30
ADediting_1215954ENST00000439211.7chr5_80628176_-1969-1297.00-1293.50-1385.30
ADediting_1215955ENST00000439211.7chr5_80628179_-1966-1299.70-1293.50-1385.30
ADediting_1215938ENST00000505337.5chr5_80628021_-1715-542.90-542.40-566.30
ADediting_1215939ENST00000505337.5chr5_80628024_-1712-542.70-542.40-566.30
ADediting_1215940ENST00000505337.5chr5_80628036_-1700-543.40-542.40-566.30
ADediting_1215941ENST00000505337.5chr5_80628038_-1698-542.50-542.40-566.30
ADediting_1215942ENST00000505337.5chr5_80628041_-1695-544.40-542.40-566.30
ADediting_1215943ENST00000505337.5chr5_80628047_-1689-543.20-542.40-566.30
ADediting_1215944ENST00000505337.5chr5_80628054_-1682-543.20-542.40-566.30
ADediting_1215945ENST00000505337.5chr5_80628076_-1660-545.70-542.40-566.30
ADediting_1215946ENST00000505337.5chr5_80628087_-1649-544.00-542.40-566.30
ADediting_1215947ENST00000505337.5chr5_80628093_-1643-545.20-542.40-566.30
ADediting_1215948ENST00000505337.5chr5_80628097_-1639-544.30-542.40-566.30
ADediting_1215949ENST00000505337.5chr5_80628100_-1636-542.40-542.40-566.30
ADediting_1215950ENST00000505337.5chr5_80628101_-1635-543.70-542.40-566.30
ADediting_1215951ENST00000505337.5chr5_80628126_-1610-544.70-542.40-566.30
ADediting_1215952ENST00000505337.5chr5_80628133_-1603-541.70-542.40-566.30
ADediting_1215953ENST00000505337.5chr5_80628171_-1565-544.30-542.40-566.30
ADediting_1215954ENST00000505337.5chr5_80628176_-1560-542.10-542.40-566.30
ADediting_1215955ENST00000505337.5chr5_80628179_-1557-545.40-542.40-566.30
ADediting_1215951ENST00000511032.5chr5_80628126_-1472-409.90-409.90-415.60
ADediting_1215952ENST00000511032.5chr5_80628133_-1465-411.10-409.90-415.60
ADediting_1215953ENST00000511032.5chr5_80628171_-1427-414.40-409.90-415.60
ADediting_1215954ENST00000511032.5chr5_80628176_-1422-411.40-409.90-415.60
ADediting_1215955ENST00000511032.5chr5_80628179_-1419-411.90-409.90-415.60

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for DHFR

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_1215893chr5_80627466_-1.04300628103298e-060.3863616429708040.0002801208491812250.2925650744989920.838295295631634-0.016801991925289
TCXADediting_1215893chr5_80627466_-0.003191189094124230.2392546354471061.09128359282746e-050.3505832706472870.0151054015756539-0.198082872287246
CERADediting_1215894chr5_80627470_-0.0001567427371703060.3038583222795530.01225322303302850.2040636760676190.935858155424616-0.0066262518395991
TCXADediting_1215894chr5_80627470_-0.002178271218553720.2483828136965014.78441596567816e-050.325611344599070.00134301814387607-0.259490824839754
STGADediting_1215895chr5_80627474_-0.6651516234574470.04791442441914090.9722194416078710.003857484392356530.004747505185430660.305272685196002
CERADediting_1215899chr5_80627492_-2.44145756381436e-060.3738892507714632.41907605533071e-050.3374010649497010.9613570556105380.0039893399929197
TCXADediting_1215899chr5_80627492_-2.48126786021631e-060.3736469774380223.63371738197269e-070.4011448181959020.0206059515368642-0.188904424887691
CERADediting_1215913chr5_80627540_-0.004175256458352670.2326228195779360.0001072589264691270.310996599985290.543398182662709-0.0500043095463414
CERADediting_1215914chr5_80627541_-0.0002893920509925430.2919178101474820.0001619027380279790.3032403124660760.487656194291691-0.0570996569338849
TCXADediting_1215914chr5_80627541_-3.97895974026523e-050.3288460600333961.49202313751487e-060.3811738729265990.251849608947146-0.0941393430876966
CERADediting_1215927chr5_80627605_-0.0003359057690386290.2889352361644326.23121450145122e-050.3209105666487630.01932757838562970.190828731682712
CERADediting_1215931chr5_80627947_-0.0001192601503611650.3090191403944392.01494916418609e-070.4091101114430.3974853488043510.0695837865380822
CERADediting_1215934chr5_80627969_-6.20440077949778e-060.3595883857632642.47113671039802e-060.3737082802541630.2754900657674720.0896098520825731
ACADediting_1215935chr5_80627974_-9.11501536459356e-070.3046398943465691.4845259771622e-050.2701582014952160.05423908028352260.12189929353956
CERADediting_1215937chr5_80628007_-3.39951380964333e-090.4592425566105113.32534270882571e-080.4322420233833850.2587657143716680.0927851650338162
CERADediting_1215939chr5_80628024_-4.11010147587441e-090.4570826758712281.48633005223446e-090.4684850720643860.5944773474396760.0438125650681324
CERADediting_1215945chr5_80628076_-2.04048850341877e-050.3402699461189343.44372457562525e-080.4318089927769540.572852123803458-0.0464020156122903
CERADediting_1215947chr5_80628093_-2.04863569320701e-090.4649330665914087.67859089186688e-060.3562209314160230.498268572732460.0557176270174465
CERADediting_1215953chr5_80628171_-0.0007488343776792890.2723025256562533.89353877436932e-070.4001982022176580.9966017758441830.000350684041580048
CERADediting_1215955chr5_80628179_-0.0005093749428878670.2804257337894683.54092223369433e-070.4014986434322250.3115928695639230.0831726190595471
DLPFCADediting_1215957chr5_80630082_-0.883219826551689-0.008376413100247040.0180526287617714-0.1342306219598641.96769403871013e-130.401436648516856
DLPFCADediting_1215958chr5_80630092_-0.9711112660277380.002065190215275450.0408845626647317-0.1162068143066345.46150791559196e-170.451669989834085
DLPFCADediting_1215962chr5_80630153_-0.626243668260711-0.02776775699953480.0101688269296569-0.1457765179865117.26267347350835e-140.40801734380879

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.63055140603808e-120.3869731176796441.70802750974747e-130.4023799377872550.03383613178567760.120569659001073
AC1.56799551951256e-530.7851742199711851.32447796060647e-320.6596621193811593.55787929828594e-200.538198245718884
PCC2.74124333322917e-070.3616545285018099.75128088301653e-090.4001293054314980.007458600026020620.193045420737098
CER2.8881200168255e-210.6747412591948076.09786321155286e-220.6830221439234460.007823340020538970.216386605081674
TCX1.67916912392623e-050.34352074184920.9509153056639230.005068508640012771.88329800251609e-090.465868547810783
FP3.46297464294284e-070.3708867847410740.0001047994841346920.2866524828420650.002011754269191920.23000104147339
PG1.0703621661714e-320.7336346329270495.23812402263717e-160.5485892653452380.200130999342850.0943669394928301
STG0.002112815968228950.3308480613282440.02054160852480420.2524047973611450.0005825000176455210.367573422920044

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Relation with AD stages for DHFR

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_1215934chr5_80627969_-4.93857620312117e-050.380185358728139
IFGADediting_1215901chr5_80627510_-0.009421533869624490.508637368330032
IFGADediting_1215904chr5_80627515_-0.00301621047054580.568654731101904
IFGADediting_1215918chr5_80627559_-0.03871768498079440.415790006692857

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER5.92886180130043e-050.376468611795564
TCX0.0002286539177427710.350647735204545

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RelatedDrugs for DHFR

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
DHFRP00374DB00563MethotrexateDihydrofolate reductasesmall moleculeapproved
DHFRP00374DB01131ProguanilDihydrofolate reductasesmall moleculeapproved
DHFRP00374DB00642PemetrexedDihydrofolate reductasesmall moleculeapproved|investigational
DHFRP00374DB01157TrimetrexateDihydrofolate reductasesmall moleculeapproved|investigational
DHFRP00374DB06813PralatrexateDihydrofolate reductasesmall moleculeapproved|investigational
DHFRP00374DB00205PyrimethamineDihydrofolate reductasesmall moleculeapproved|investigational|vet_approved
DHFRP00374DB00440TrimethoprimDihydrofolate reductasesmall moleculeapproved|vet_approved
DHFRP00374DB00798GentamicinDihydrofolate reductasesmall moleculeapproved|vet_approved

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RelatedDiseases for DHFR

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource
DHFRC2751584Neurodegeneration Due To Cerebral Folate Transport Deficiency3GENOMICS_ENGLAND
DHFRC0002888Anemia, Megaloblastic2CTD_human
DHFRC0006142Malignant neoplasm of breast2CTD_human
DHFRC0025521Inborn Errors of Metabolism2CTD_human
DHFRC0027765nervous system disorder2CTD_human
DHFRC0678222Breast Carcinoma2CTD_human
DHFRC1257931Mammary Neoplasms, Human2CTD_human
DHFRC1458155Mammary Neoplasms2CTD_human
DHFRC3151205Megaloblastic Anemia due to Dihydrofolate Reductase Deficiency2CTD_human;ORPHANET;UNIPROT
DHFRC0000786Spontaneous abortion1CTD_human
DHFRC0000822Abortion, Tubal1CTD_human
DHFRC0003873Rheumatoid Arthritis1CTD_human
DHFRC0004352Autistic Disorder1CTD_human
DHFRC0009402Colorectal Carcinoma1CTD_human
DHFRC0009404Colorectal Neoplasms1CTD_human
DHFRC0010828Cytopenia1GENOMICS_ENGLAND
DHFRC0013221Drug toxicity1CTD_human
DHFRC0016412Folic Acid Deficiency1CTD_human
DHFRC0019193Hepatitis, Toxic1CTD_human
DHFRC0021361Female infertility1CTD_human
DHFRC0027627Neoplasm Metastasis1CTD_human
DHFRC0029463Osteosarcoma1CTD_human
DHFRC0030312Pancytopenia1CTD_human
DHFRC0038279Sterility, Postpartum1CTD_human
DHFRC0041755Adverse reaction to drug1CTD_human
DHFRC0158995Congenital anemia1GENOMICS_ENGLAND
DHFRC0341869Subfertility, Female1CTD_human
DHFRC0860207Drug-Induced Liver Disease1CTD_human
DHFRC0917730Female sterility1CTD_human
DHFRC1262760Hepatitis, Drug-Induced1CTD_human
DHFRC1527249Colorectal Cancer1CTD_human
DHFRC3658290Drug-Induced Acute Liver Injury1CTD_human
DHFRC4277682Chemical and Drug Induced Liver Injury1CTD_human
DHFRC4279912Chemically-Induced Liver Toxicity1CTD_human