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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for ITPRIPL2 |
 Gene summary |
| Gene information | Gene symbol | ITPRIPL2 | Gene ID | 162073 |
| Gene name | ITPRIP like 2 | |
| Synonyms | - | |
| Cytomap | 16p12.3 | |
| Type of gene | protein-coding | |
| Description | inositol 1,4,5-trisphosphate receptor-interacting protein-like 2inositol 1,4,5-triphosphate receptor-interacting protein-like 2inositol 1,4,5-trisphosphate receptor interacting protein like 2 | |
| Modification date | 20200313 | |
| UniProtAcc | Q3MIP1, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for ITPRIPL2 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_520657(19118201, +), ADediting_520658(19118209, +), ADediting_520659(19118210, +), ADediting_520660(19118244, +), ADediting_520661(19118262, +), ADediting_520662(19118273, +), ADediting_520663(19118282, +), ADediting_520664(19118318, +), ADediting_520665(19118344, +), ADediting_520666(19118345, +), ADediting_520667(19118366, +), ADediting_520668(19118367, +), ADediting_520669(19118371, +), ADediting_520670(19118377, +), ADediting_520671(19118380, +), ADediting_520672(19118386, +), ADediting_520673(19118399, +), ADediting_520674(19118406, +), ADediting_520675(19118408, +), ADediting_520676(19118414, +), ADediting_520677(19118415, +), ADediting_520678(19119737, +), ADediting_520679(19119738, +), ADediting_1541240(19118278, +), |
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RNA editing positional annotations for ITPRIPL2 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_520657 | chr16_19118201_+ | ncRNA_intronic |
| ADediting_520658 | chr16_19118209_+ | ncRNA_intronic |
| ADediting_520659 | chr16_19118210_+ | ncRNA_intronic |
| ADediting_520660 | chr16_19118244_+ | ncRNA_intronic |
| ADediting_520661 | chr16_19118262_+ | ncRNA_intronic |
| ADediting_520662 | chr16_19118273_+ | ncRNA_intronic |
| ADediting_520663 | chr16_19118282_+ | ncRNA_intronic |
| ADediting_520664 | chr16_19118318_+ | ncRNA_intronic |
| ADediting_520665 | chr16_19118344_+ | ncRNA_intronic |
| ADediting_520666 | chr16_19118345_+ | ncRNA_intronic |
| ADediting_520667 | chr16_19118366_+ | ncRNA_intronic |
| ADediting_520668 | chr16_19118367_+ | ncRNA_intronic |
| ADediting_520669 | chr16_19118371_+ | ncRNA_intronic |
| ADediting_520670 | chr16_19118377_+ | ncRNA_intronic |
| ADediting_520671 | chr16_19118380_+ | ncRNA_intronic |
| ADediting_520672 | chr16_19118386_+ | ncRNA_intronic |
| ADediting_520673 | chr16_19118399_+ | ncRNA_intronic |
| ADediting_520674 | chr16_19118406_+ | ncRNA_intronic |
| ADediting_520675 | chr16_19118408_+ | ncRNA_intronic |
| ADediting_520676 | chr16_19118414_+ | ncRNA_intronic |
| ADediting_520677 | chr16_19118415_+ | ncRNA_intronic |
| ADediting_520678 | chr16_19119737_+ | ncRNA_intronic |
| ADediting_520679 | chr16_19119738_+ | ncRNA_intronic |
| ADediting_1541240 | chr16_19118278_+ | ncRNA_intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_520657 | chr16_19118201_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520658 | chr16_19118209_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520659 | chr16_19118210_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520660 | chr16_19118244_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520661 | chr16_19118262_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520662 | chr16_19118273_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520663 | chr16_19118282_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520664 | chr16_19118318_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520665 | chr16_19118344_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520666 | chr16_19118345_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520667 | chr16_19118366_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520668 | chr16_19118367_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520669 | chr16_19118371_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520670 | chr16_19118377_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520671 | chr16_19118380_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520672 | chr16_19118386_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520673 | chr16_19118399_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520674 | chr16_19118406_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520675 | chr16_19118408_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520676 | chr16_19118414_+ | SINE | Alu | Name=AluSx1 |
| ADediting_520677 | chr16_19118415_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1541240 | chr16_19118278_+ | SINE | Alu | Name=AluSx1 |
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RNA A-to-I editing events in the alternative splicing sites for ITPRIPL2 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ITPRIPL2 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for ITPRIPL2 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for ITPRIPL2 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1541240 | chr16_19118278_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-4794 | chr16 | 19118271 | 19118277 | 7mer-m8 | 19118257 | 19118278 | 140 | -13.25 |
| ADediting_1541240 | chr16_19118278_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-5580-5p | chr16 | 19118272 | 19118279 | 8mer-1a | 19118258 | 19118279 | 140 | -13.97 |
| ADediting_1541240 | chr16_19118278_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-664a-5p | chr16 | 19118271 | 19118277 | 7mer-m8 | 19118255 | 19118278 | 150 | -21.92 |
| ADediting_520657 | chr16_19118201_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-4634 | chr16 | 19118198 | 19118204 | 7mer-m8 | 19118186 | 19118205 | 151 | -24.1 |
| ADediting_520658 | chr16_19118209_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-513a-5p | chr16 | 19118203 | 19118209 | 7mer-m8 | 19118193 | 19118210 | 144 | -16.68 |
| ADediting_520658 | chr16_19118209_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-638 | chr16 | 19118208 | 19118214 | 7mer-1a | 19118190 | 19118214 | 159 | -35.77 |
| ADediting_520659 | chr16_19118210_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-8052 | chr16 | 19118208 | 19118214 | 7mer-1a | 19118196 | 19118214 | 140 | -24.15 |
| ADediting_520662 | chr16_19118273_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-4435 | chr16 | 19118270 | 19118277 | 8mer-1a | 19118257 | 19118277 | 146 | -17.76 |
| ADediting_520662 | chr16_19118273_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-4755-3p | chr16 | 19118268 | 19118274 | 7mer-m8 | 19118254 | 19118275 | 145 | -16.93 |
| ADediting_520663 | chr16_19118282_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-4716-5p | chr16 | 19118276 | 19118282 | 7mer-m8 | 19118262 | 19118283 | 144 | -10.91 |
| ADediting_520665 | chr16_19118344_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-513a-5p | chr16 | 19118338 | 19118344 | 7mer-m8 | 19118328 | 19118345 | 140 | -18.01 |
| ADediting_520665 | chr16_19118344_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-638 | chr16 | 19118343 | 19118349 | 7mer-1a | 19118325 | 19118349 | 155 | -34.54 |
| ADediting_520666 | chr16_19118345_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-8052 | chr16 | 19118343 | 19118349 | 7mer-1a | 19118329 | 19118349 | 141 | -23.11 |
| ADediting_520668 | chr16_19118367_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-18a-3p | chr16 | 19118365 | 19118371 | 7mer-m8 | 19118352 | 19118372 | 154 | -24.74 |
| ADediting_520668 | chr16_19118367_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-3157-3p | chr16 | 19118364 | 19118370 | 7mer-m8 | 19118351 | 19118371 | 160 | -30.02 |
| ADediting_520672 | chr16_19118386_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-4437 | chr16 | 19118382 | 19118388 | 7mer-m8 | 19118369 | 19118389 | 146 | -19.54 |
| ADediting_520675 | chr16_19118408_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-10398-5p | chr16 | 19118406 | 19118413 | 8mer-1a | 19118391 | 19118413 | 154 | -26.12 |
| ADediting_520675 | chr16_19118408_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-7106-3p | chr16 | 19118405 | 19118411 | 7mer-m8 | 19118390 | 19118412 | 160 | -24.6 |
| ADediting_520675 | chr16_19118408_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-7113-3p | chr16 | 19118404 | 19118410 | 7mer-m8 | 19118384 | 19118411 | 154 | -27.89 |
| ADediting_520676 | chr16_19118414_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-4638-5p | chr16 | 19118409 | 19118416 | 8mer-1a | 19118397 | 19118416 | 142 | -17.39 |
| ADediting_520677 | chr16_19118415_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-149-5p | chr16 | 19118408 | 19118414 | 7mer-m8 | 19118390 | 19118415 | 159 | -29.37 |
| ADediting_520678 | chr16_19119737_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-130a-5p | chr16 | 19119732 | 19119738 | 7mer-m8 | 19119718 | 19119739 | 152 | -11.43 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1541240 | chr16_19118278_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-4781-3p | chr16 | 19118274 | 19118281 | 8mer-1a | 19118258 | 19118281 | 142 | -11.69 |
| ADediting_520657 | chr16_19118201_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-6807-5p | chr16 | 19118194 | 19118200 | 7mer-m8 | 19118180 | 19118201 | 140 | -16.43 |
| ADediting_520658 | chr16_19118209_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-10399-5p | chr16 | 19118204 | 19118210 | 7mer-m8 | 19118190 | 19118211 | 144 | -10.39 |
| ADediting_520658 | chr16_19118209_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-6504-3p | chr16 | 19118204 | 19118210 | 7mer-m8 | 19118190 | 19118211 | 148 | -14.48 |
| ADediting_520658 | chr16_19118209_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-7151-3p | chr16 | 19118202 | 19118209 | 8mer-1a | 19118189 | 19118209 | 144 | -16.51 |
| ADediting_520659 | chr16_19118210_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-10399-5p | chr16 | 19118204 | 19118210 | 7mer-m8 | 19118190 | 19118211 | 144 | -10.39 |
| ADediting_520659 | chr16_19118210_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-5089-5p | chr16 | 19118208 | 19118214 | 7mer-m8 | 19118193 | 19118215 | 148 | -14.13 |
| ADediting_520659 | chr16_19118210_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-6504-3p | chr16 | 19118204 | 19118210 | 7mer-m8 | 19118190 | 19118211 | 148 | -14.48 |
| ADediting_520660 | chr16_19118244_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-125a-3p | chr16 | 19118241 | 19118248 | 8mer-1a | 19118227 | 19118248 | 140 | -18.15 |
| ADediting_520662 | chr16_19118273_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-6069 | chr16 | 19118269 | 19118276 | 8mer-1a | 19118258 | 19118276 | 144 | -15.82 |
| ADediting_520664 | chr16_19118318_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-4735-5p | chr16 | 19118312 | 19118318 | 7mer-m8 | 19118298 | 19118319 | 140 | -4.28 |
| ADediting_520665 | chr16_19118344_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-10399-5p | chr16 | 19118339 | 19118345 | 7mer-m8 | 19118327 | 19118346 | 141 | -12.5 |
| ADediting_520665 | chr16_19118344_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-6504-3p | chr16 | 19118339 | 19118345 | 7mer-m8 | 19118325 | 19118346 | 148 | -14.75 |
| ADediting_520665 | chr16_19118344_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-7151-3p | chr16 | 19118337 | 19118344 | 8mer-1a | 19118324 | 19118344 | 140 | -12.68 |
| ADediting_520666 | chr16_19118345_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-10399-5p | chr16 | 19118339 | 19118345 | 7mer-m8 | 19118327 | 19118346 | 141 | -12.5 |
| ADediting_520666 | chr16_19118345_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-5089-5p | chr16 | 19118343 | 19118349 | 7mer-m8 | 19118330 | 19118350 | 144 | -13.27 |
| ADediting_520666 | chr16_19118345_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-6504-3p | chr16 | 19118339 | 19118345 | 7mer-m8 | 19118325 | 19118346 | 148 | -14.75 |
| ADediting_520669 | chr16_19118371_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-1976 | chr16 | 19118368 | 19118375 | 8mer-1a | 19118354 | 19118375 | 152 | -22.93 |
| ADediting_520669 | chr16_19118371_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-6747-3p | chr16 | 19118366 | 19118373 | 8mer-1a | 19118351 | 19118373 | 153 | -24.06 |
| ADediting_520670 | chr16_19118377_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-8062 | chr16 | 19118375 | 19118381 | 7mer-m8 | 19118362 | 19118382 | 141 | -10.43 |
| ADediting_520671 | chr16_19118380_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-8062 | chr16 | 19118375 | 19118381 | 7mer-m8 | 19118362 | 19118382 | 141 | -10.43 |
| ADediting_520673 | chr16_19118399_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-412-3p | chr16 | 19118393 | 19118399 | 7mer-m8 | 19118374 | 19118400 | 146 | -16.24 |
| ADediting_520673 | chr16_19118399_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-6754-3p | chr16 | 19118393 | 19118399 | 7mer-m8 | 19118379 | 19118400 | 152 | -19.89 |
| ADediting_520674 | chr16_19118406_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-6817-3p | chr16 | 19118404 | 19118410 | 7mer-m8 | 19118393 | 19118411 | 143 | -16.58 |
| ADediting_520675 | chr16_19118408_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-6817-3p | chr16 | 19118404 | 19118410 | 7mer-m8 | 19118393 | 19118411 | 143 | -16.58 |
| ADediting_520676 | chr16_19118414_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-8057 | chr16 | 19118407 | 19118414 | 8mer-1a | 19118395 | 19118414 | 149 | -15.06 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-589-3p | chr16 | 19119885 | 19119891 | 7mer-m8 | 19119870 | 19119892 | 159 | -20.95 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-151a-3p | chr16 | 19116232 | 19116238 | 7mer-m8 | 19116217 | 19116239 | 147 | -22.06 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-151a-3p | chr16 | 19117577 | 19117584 | 8mer-1a | 19117566 | 19117584 | 146 | -12.41 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-4477b | chr16 | 19117515 | 19117521 | 7mer-m8 | 19117501 | 19117522 | 163 | -15.81 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-4477b | chr16 | 19118631 | 19118637 | 7mer-m8 | 19118617 | 19118638 | 143 | -10.78 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-337-3p | chr16 | 19117784 | 19117791 | 8mer-1a | 19117771 | 19117791 | 154 | -11.88 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-641 | chr16 | 19118906 | 19118912 | 7mer-m8 | 19118892 | 19118913 | 164 | -24.1 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-641 | chr16 | 19120995 | 19121001 | 7mer-m8 | 19120980 | 19121002 | 168 | -19.68 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-5585-3p | chr16 | 19116920 | 19116926 | 7mer-m8 | 19116904 | 19116927 | 158 | -21.4 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-5688 | chr16 | 19118586 | 19118592 | 7mer-1a | 19118570 | 19118592 | 143 | -16.19 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-589-3p | chr16 | 19116329 | 19116335 | 7mer-m8 | 19116308 | 19116336 | 153 | -19.08 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-641 | chr16 | 19121338 | 19121344 | 7mer-m8 | 19121325 | 19121345 | 153 | -15.03 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-641 | chr16 | 19121338 | 19121344 | 7mer-m8 | 19121325 | 19121345 | 153 | -15.03 |
| ADediting_291761 | chr11_93733708_- | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-1304-3p | chr16 | 19118521 | 19118527 | 7mer-m8 | 19118505 | 19118528 | 149 | -12.8 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000205730.6 | ENST00000381440.4 | ITPRIPL2-201 | hsa-miR-4775 | chr16 | 19118018 | 19118024 | 7mer-m8 | 19118004 | 19118025 | 140 | -7.2 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for ITPRIPL2 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000381440.4 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_520657 | ENST00000381440.4 | chr16_19118201_+ | 3819 | -2744.81 | -2745.21 | -2760.84 |
| ADediting_520658 | ENST00000381440.4 | chr16_19118209_+ | 3827 | -2745.31 | -2745.21 | -2760.84 |
| ADediting_520659 | ENST00000381440.4 | chr16_19118210_+ | 3828 | -2745.21 | -2745.21 | -2760.84 |
| ADediting_520660 | ENST00000381440.4 | chr16_19118244_+ | 3862 | -2744.81 | -2745.21 | -2760.84 |
| ADediting_520661 | ENST00000381440.4 | chr16_19118262_+ | 3880 | -2751.21 | -2745.21 | -2760.84 |
| ADediting_520662 | ENST00000381440.4 | chr16_19118273_+ | 3891 | -2751.81 | -2745.21 | -2760.84 |
| ADediting_1541240 | ENST00000381440.4 | chr16_19118278_+ | 3896 | -2745.21 | -2745.21 | -2760.84 |
| ADediting_520663 | ENST00000381440.4 | chr16_19118282_+ | 3900 | -2750.71 | -2745.21 | -2760.84 |
| ADediting_520664 | ENST00000381440.4 | chr16_19118318_+ | 3936 | -2744.91 | -2745.21 | -2760.84 |
| ADediting_520665 | ENST00000381440.4 | chr16_19118344_+ | 3962 | -2745.31 | -2745.21 | -2760.84 |
| ADediting_520666 | ENST00000381440.4 | chr16_19118345_+ | 3963 | -2745.21 | -2745.21 | -2760.84 |
| ADediting_520667 | ENST00000381440.4 | chr16_19118366_+ | 3984 | -2745.31 | -2745.21 | -2760.84 |
| ADediting_520668 | ENST00000381440.4 | chr16_19118367_+ | 3985 | -2744.91 | -2745.21 | -2760.84 |
| ADediting_520669 | ENST00000381440.4 | chr16_19118371_+ | 3989 | -2744.41 | -2745.21 | -2760.84 |
| ADediting_520670 | ENST00000381440.4 | chr16_19118377_+ | 3995 | -2745.21 | -2745.21 | -2760.84 |
| ADediting_520671 | ENST00000381440.4 | chr16_19118380_+ | 3998 | -2744.81 | -2745.21 | -2760.84 |
| ADediting_520672 | ENST00000381440.4 | chr16_19118386_+ | 4004 | -2745.21 | -2745.21 | -2760.84 |
| ADediting_520673 | ENST00000381440.4 | chr16_19118399_+ | 4017 | -2745.21 | -2745.21 | -2760.84 |
| ADediting_520674 | ENST00000381440.4 | chr16_19118406_+ | 4024 | -2744.51 | -2745.21 | -2760.84 |
| ADediting_520675 | ENST00000381440.4 | chr16_19118408_+ | 4026 | -2745.61 | -2745.21 | -2760.84 |
| ADediting_520676 | ENST00000381440.4 | chr16_19118414_+ | 4032 | -2744.91 | -2745.21 | -2760.84 |
| ADediting_520677 | ENST00000381440.4 | chr16_19118415_+ | 4033 | -2744.91 | -2745.21 | -2760.84 |
| ADediting_520678 | ENST00000381440.4 | chr16_19119737_+ | 5355 | -2747.04 | -2745.21 | -2760.84 |
| ADediting_520679 | ENST00000381440.4 | chr16_19119738_+ | 5356 | -2747.14 | -2745.21 | -2760.84 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for ITPRIPL2 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 2.98876140001481e-07 | 0.286082957778082 | 0.900456711667881 | -0.00713304348378037 | 6.07911504185211e-68 | 0.791893651605728 |
| AC | 2.29461846828323e-10 | 0.387181104243623 | 1.99570127279159e-05 | 0.266215906050851 | 2.66238585540397e-08 | 0.342792410797155 |
| PCC | 0.0958596715992777 | 0.12084569812953 | 0.622440738702747 | 0.0358522769045917 | 8.13353170871368e-07 | 0.347946159835969 |
| CER | 8.51175953041066e-11 | 0.498469661584642 | 1.32841183001285e-05 | 0.347381886206228 | 2.03093172478136e-09 | 0.46502968476106 |
| TCX | 4.2188149816774e-07 | 0.399094738029796 | 0.685880169678729 | 0.0332927410001063 | 0.000145317500093133 | 0.305297088196689 |
| FP | 0.0209248355101568 | 0.173003772185406 | 0.77241122048082 | 0.0218293424670538 | 1.79109319568828e-12 | 0.496598989249456 |
| IFG | 0.0270146500591161 | 0.441837677835817 | 0.00725983379515074 | 0.52335384485512 | 0.000333451101797095 | 0.659732755860758 |
| PG | 4.82388267559866e-12 | 0.478679942409075 | 2.61316982109108e-06 | 0.33670969808112 | 0.00485236492872484 | 0.205701989372165 |
| STG | 0.733498124692741 | 0.0377006633292614 | 0.144179348680518 | -0.160713345171314 | 2.17868769513028e-05 | 0.445427867720348 |
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Relation with AD stages for ITPRIPL2 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 2.36016487697285e-05 | 0.394761361609787 |
| TCX | 2.02781900520516e-10 | 0.5686710933757 |
| PG | 4.44778350164908e-09 | 0.413537295836012 |
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RelatedDrugs for ITPRIPL2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ITPRIPL2 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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