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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for DAPK3 |
 Gene summary |
| Gene information | Gene symbol | DAPK3 | Gene ID | 1613 |
| Gene name | death associated protein kinase 3 | |
| Synonyms | DLK|ZIP|ZIPK | |
| Cytomap | 19p13.3 | |
| Type of gene | protein-coding | |
| Description | death-associated protein kinase 3DAP kinase 3DAP-like kinaseMYPT1 kinaseZIP-kinasezipper-interacting protein kinase | |
| Modification date | 20200329 | |
| UniProtAcc | O43293, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| DAPK3 | GO:0006468 | protein phosphorylation | 10356987 |
| DAPK3 | GO:0006915 | apoptotic process | 10580117 |
| DAPK3 | GO:0017148 | negative regulation of translation | 18995835 |
| DAPK3 | GO:0035556 | intracellular signal transduction | 10356987 |
| DAPK3 | GO:0043065 | positive regulation of apoptotic process | 21487036 |
| DAPK3 | GO:0046777 | protein autophosphorylation | 18239682 |
| DAPK3 | GO:0051893 | regulation of focal adhesion assembly | 23454120 |
| DAPK3 | GO:0071346 | cellular response to interferon-gamma | 18995835 |
| DAPK3 | GO:2000249 | regulation of actin cytoskeleton reorganization | 23454120 |
Top |
RNA A-to-I events for DAPK3 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_750025(3961906, -), ADediting_750026(3961911, -), ADediting_750027(3961924, -), ADediting_750028(3961951, -), ADediting_750029(3961955, -), ADediting_750030(3961956, -), ADediting_750031(3961959, -), ADediting_750032(3961970, -), ADediting_750033(3961983, -), ADediting_750034(3961987, -), ADediting_750035(3961991, -), ADediting_750036(3961997, -), ADediting_750037(3962010, -), ADediting_750038(3962023, -), ADediting_750039(3962026, -), ADediting_750040(3962027, -), ADediting_750041(3962028, -), ADediting_750042(3962029, -), ADediting_750043(3962032, -), ADediting_750044(3962034, -), ADediting_750045(3962035, -), ADediting_750046(3962036, -), ADediting_750047(3962038, -), ADediting_750048(3962041, -), ADediting_750049(3962052, -), ADediting_750050(3962053, -), ADediting_750051(3962054, -), ADediting_750052(3962057, -), ADediting_750053(3962060, -), ADediting_750054(3962062, -), ADediting_750055(3962086, -), ADediting_750056(3962091, -), ADediting_750057(3962094, -), ADediting_750058(3962099, -), ADediting_750059(3962113, -), ADediting_750060(3962121, -), ADediting_750061(3962129, -), ADediting_750062(3962130, -), ADediting_750063(3962138, -), ADediting_750064(3962145, -), ADediting_750065(3962519, -), ADediting_750066(3962530, -), ADediting_750067(3962533, -), ADediting_750068(3962593, -), ADediting_750069(3962610, -), ADediting_750070(3962613, -), ADediting_750071(3962619, -), ADediting_750072(3962628, -), ADediting_750073(3962629, -), ADediting_750074(3962642, -), ADediting_750075(3962653, -), ADediting_750076(3962655, -), ADediting_750077(3962665, -), ADediting_750078(3962668, -), ADediting_750079(3962669, -), ADediting_750080(3962677, -), ADediting_750081(3962684, -), ADediting_750082(3962694, -), ADediting_750083(3962695, -), ADediting_750084(3962720, -), ADediting_750085(3962731, -), ADediting_750086(3962761, -), ADediting_750087(3962782, -), ADediting_750088(3962844, -), ADediting_750089(3962856, -), ADediting_750090(3962857, -), ADediting_750091(3962919, -), ADediting_750092(3962939, -), ADediting_750093(3962953, -), ADediting_750094(3962967, -), ADediting_750095(3962970, -), ADediting_750096(3962990, -), ADediting_750097(3963002, -), ADediting_750098(3963015, -), ADediting_750099(3963019, -), ADediting_750100(3963020, -), ADediting_750101(3963026, -), ADediting_750102(3963045, -), ADediting_750103(3963053, -), ADediting_750104(3963079, -), ADediting_750105(3963178, -), ADediting_750106(3963190, -), ADediting_750107(3963197, -), ADediting_750108(3963221, -), ADediting_750109(3963251, -), ADediting_750110(3963261, -), ADediting_750111(3963378, -), ADediting_750112(3965399, -), ADediting_750113(3965425, -), ADediting_750114(3965434, -), ADediting_750115(3965437, -), ADediting_750116(3965496, -), ADediting_750117(3965506, -), ADediting_750118(3965509, -), ADediting_750119(3965535, -), ADediting_750120(3965536, -), ADediting_750121(3965555, -), ADediting_750122(3965571, -), ADediting_750123(3965700, -), ADediting_750124(3965703, -), ADediting_750125(3965757, -), ADediting_750126(3965762, -), ADediting_750127(3965788, -), ADediting_750128(3965797, -), ADediting_750129(3965803, -), ADediting_750130(3965865, -), ADediting_750131(3965927, -), ADediting_750132(3965940, -), ADediting_750133(3965980, -), ADediting_750134(3965981, -), ADediting_750135(3966002, -), ADediting_750136(3966012, -), ADediting_750137(3966017, -), ADediting_750138(3966288, -), ADediting_750139(3967655, -), ADediting_750140(3968047, -), ADediting_750141(3968055, -), ADediting_750142(3968238, -), ADediting_750143(3968250, -), ADediting_750144(3968251, -), ADediting_750145(3968320, -), ADediting_750146(3968373, -), ADediting_750147(3968395, -), ADediting_750148(3968433, -), ADediting_750149(3969259, -), ADediting_750150(3969264, -), ADediting_750151(3969277, -), ADediting_750152(3969290, -), ADediting_1555969(3960722, -), ADediting_1555970(3961948, -), ADediting_1555971(3962049, -), ADediting_1555972(3962107, -), ADediting_1555973(3962124, -), ADediting_1555974(3962566, -), ADediting_1555975(3962780, -), ADediting_1555976(3962858, -), ADediting_1555977(3962909, -), ADediting_1555978(3962936, -), ADediting_1555979(3962945, -), ADediting_1555980(3965726, -), ADediting_1555981(3965776, -), ADediting_1555982(3966050, -), ADediting_1555983(3967252, -), ADediting_1555984(3968079, -), |
Top |
RNA editing positional annotations for DAPK3 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_750025 | chr19_3961906_- | intronic |
| ADediting_750026 | chr19_3961911_- | intronic |
| ADediting_750027 | chr19_3961924_- | intronic |
| ADediting_750028 | chr19_3961951_- | intronic |
| ADediting_750029 | chr19_3961955_- | intronic |
| ADediting_750030 | chr19_3961956_- | intronic |
| ADediting_750031 | chr19_3961959_- | intronic |
| ADediting_750032 | chr19_3961970_- | intronic |
| ADediting_750033 | chr19_3961983_- | intronic |
| ADediting_750034 | chr19_3961987_- | intronic |
| ADediting_750035 | chr19_3961991_- | intronic |
| ADediting_750036 | chr19_3961997_- | intronic |
| ADediting_750037 | chr19_3962010_- | intronic |
| ADediting_750038 | chr19_3962023_- | intronic |
| ADediting_750039 | chr19_3962026_- | intronic |
| ADediting_750040 | chr19_3962027_- | intronic |
| ADediting_750041 | chr19_3962028_- | intronic |
| ADediting_750042 | chr19_3962029_- | intronic |
| ADediting_750043 | chr19_3962032_- | intronic |
| ADediting_750044 | chr19_3962034_- | intronic |
| ADediting_750045 | chr19_3962035_- | intronic |
| ADediting_750046 | chr19_3962036_- | intronic |
| ADediting_750047 | chr19_3962038_- | intronic |
| ADediting_750048 | chr19_3962041_- | intronic |
| ADediting_750049 | chr19_3962052_- | intronic |
| ADediting_750050 | chr19_3962053_- | intronic |
| ADediting_750051 | chr19_3962054_- | intronic |
| ADediting_750052 | chr19_3962057_- | intronic |
| ADediting_750053 | chr19_3962060_- | intronic |
| ADediting_750054 | chr19_3962062_- | intronic |
| ADediting_750055 | chr19_3962086_- | intronic |
| ADediting_750056 | chr19_3962091_- | intronic |
| ADediting_750057 | chr19_3962094_- | intronic |
| ADediting_750058 | chr19_3962099_- | intronic |
| ADediting_750059 | chr19_3962113_- | intronic |
| ADediting_750060 | chr19_3962121_- | intronic |
| ADediting_750061 | chr19_3962129_- | intronic |
| ADediting_750062 | chr19_3962130_- | intronic |
| ADediting_750063 | chr19_3962138_- | intronic |
| ADediting_750064 | chr19_3962145_- | intronic |
| ADediting_750065 | chr19_3962519_- | intronic |
| ADediting_750066 | chr19_3962530_- | intronic |
| ADediting_750067 | chr19_3962533_- | intronic |
| ADediting_750068 | chr19_3962593_- | intronic |
| ADediting_750069 | chr19_3962610_- | intronic |
| ADediting_750070 | chr19_3962613_- | intronic |
| ADediting_750071 | chr19_3962619_- | intronic |
| ADediting_750072 | chr19_3962628_- | intronic |
| ADediting_750073 | chr19_3962629_- | intronic |
| ADediting_750074 | chr19_3962642_- | intronic |
| ADediting_750075 | chr19_3962653_- | intronic |
| ADediting_750076 | chr19_3962655_- | intronic |
| ADediting_750077 | chr19_3962665_- | intronic |
| ADediting_750078 | chr19_3962668_- | intronic |
| ADediting_750079 | chr19_3962669_- | intronic |
| ADediting_750080 | chr19_3962677_- | intronic |
| ADediting_750081 | chr19_3962684_- | intronic |
| ADediting_750082 | chr19_3962694_- | intronic |
| ADediting_750083 | chr19_3962695_- | intronic |
| ADediting_750084 | chr19_3962720_- | intronic |
| ADediting_750085 | chr19_3962731_- | intronic |
| ADediting_750086 | chr19_3962761_- | intronic |
| ADediting_750087 | chr19_3962782_- | intronic |
| ADediting_750088 | chr19_3962844_- | intronic |
| ADediting_750089 | chr19_3962856_- | intronic |
| ADediting_750090 | chr19_3962857_- | intronic |
| ADediting_750091 | chr19_3962919_- | intronic |
| ADediting_750092 | chr19_3962939_- | intronic |
| ADediting_750093 | chr19_3962953_- | intronic |
| ADediting_750094 | chr19_3962967_- | intronic |
| ADediting_750095 | chr19_3962970_- | intronic |
| ADediting_750096 | chr19_3962990_- | intronic |
| ADediting_750097 | chr19_3963002_- | intronic |
| ADediting_750098 | chr19_3963015_- | intronic |
| ADediting_750099 | chr19_3963019_- | intronic |
| ADediting_750100 | chr19_3963020_- | intronic |
| ADediting_750101 | chr19_3963026_- | intronic |
| ADediting_750102 | chr19_3963045_- | intronic |
| ADediting_750103 | chr19_3963053_- | intronic |
| ADediting_750104 | chr19_3963079_- | intronic |
| ADediting_750105 | chr19_3963178_- | intronic |
| ADediting_750106 | chr19_3963190_- | intronic |
| ADediting_750107 | chr19_3963197_- | intronic |
| ADediting_750108 | chr19_3963221_- | intronic |
| ADediting_750109 | chr19_3963251_- | intronic |
| ADediting_750110 | chr19_3963261_- | intronic |
| ADediting_750111 | chr19_3963378_- | intronic |
| ADediting_750112 | chr19_3965399_- | intronic |
| ADediting_750113 | chr19_3965425_- | intronic |
| ADediting_750114 | chr19_3965434_- | intronic |
| ADediting_750115 | chr19_3965437_- | intronic |
| ADediting_750116 | chr19_3965496_- | intronic |
| ADediting_750117 | chr19_3965506_- | intronic |
| ADediting_750118 | chr19_3965509_- | intronic |
| ADediting_750119 | chr19_3965535_- | intronic |
| ADediting_750120 | chr19_3965536_- | intronic |
| ADediting_750121 | chr19_3965555_- | intronic |
| ADediting_750122 | chr19_3965571_- | intronic |
| ADediting_750123 | chr19_3965700_- | intronic |
| ADediting_750124 | chr19_3965703_- | intronic |
| ADediting_750125 | chr19_3965757_- | intronic |
| ADediting_750126 | chr19_3965762_- | intronic |
| ADediting_750127 | chr19_3965788_- | intronic |
| ADediting_750128 | chr19_3965797_- | intronic |
| ADediting_750129 | chr19_3965803_- | intronic |
| ADediting_750130 | chr19_3965865_- | intronic |
| ADediting_750131 | chr19_3965927_- | intronic |
| ADediting_750132 | chr19_3965940_- | intronic |
| ADediting_750133 | chr19_3965980_- | intronic |
| ADediting_750134 | chr19_3965981_- | intronic |
| ADediting_750135 | chr19_3966002_- | intronic |
| ADediting_750136 | chr19_3966012_- | intronic |
| ADediting_750137 | chr19_3966017_- | intronic |
| ADediting_750138 | chr19_3966288_- | intronic |
| ADediting_750139 | chr19_3967655_- | intronic |
| ADediting_750140 | chr19_3968047_- | intronic |
| ADediting_750141 | chr19_3968055_- | intronic |
| ADediting_750142 | chr19_3968238_- | intronic |
| ADediting_750143 | chr19_3968250_- | intronic |
| ADediting_750144 | chr19_3968251_- | intronic |
| ADediting_750145 | chr19_3968320_- | intronic |
| ADediting_750146 | chr19_3968373_- | intronic |
| ADediting_750147 | chr19_3968395_- | intronic |
| ADediting_750148 | chr19_3968433_- | intronic |
| ADediting_750149 | chr19_3969259_- | intronic |
| ADediting_750150 | chr19_3969264_- | intronic |
| ADediting_750151 | chr19_3969277_- | intronic |
| ADediting_750152 | chr19_3969290_- | intronic |
| ADediting_1555969 | chr19_3960722_- | intronic |
| ADediting_1555970 | chr19_3961948_- | intronic |
| ADediting_1555971 | chr19_3962049_- | intronic |
| ADediting_1555972 | chr19_3962107_- | intronic |
| ADediting_1555973 | chr19_3962124_- | intronic |
| ADediting_1555974 | chr19_3962566_- | intronic |
| ADediting_1555975 | chr19_3962780_- | intronic |
| ADediting_1555976 | chr19_3962858_- | intronic |
| ADediting_1555977 | chr19_3962909_- | intronic |
| ADediting_1555978 | chr19_3962936_- | intronic |
| ADediting_1555979 | chr19_3962945_- | intronic |
| ADediting_1555980 | chr19_3965726_- | intronic |
| ADediting_1555981 | chr19_3965776_- | intronic |
| ADediting_1555982 | chr19_3966050_- | intronic |
| ADediting_1555983 | chr19_3967252_- | intronic |
| ADediting_1555984 | chr19_3968079_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_750025 | chr19_3961906_- | SINE | Alu | Name=AluY |
| ADediting_750026 | chr19_3961911_- | SINE | Alu | Name=AluY |
| ADediting_750027 | chr19_3961924_- | SINE | Alu | Name=AluY |
| ADediting_750028 | chr19_3961951_- | SINE | Alu | Name=AluY |
| ADediting_750029 | chr19_3961955_- | SINE | Alu | Name=AluY |
| ADediting_750030 | chr19_3961956_- | SINE | Alu | Name=AluY |
| ADediting_750031 | chr19_3961959_- | SINE | Alu | Name=AluY |
| ADediting_750032 | chr19_3961970_- | SINE | Alu | Name=AluY |
| ADediting_750033 | chr19_3961983_- | SINE | Alu | Name=AluY |
| ADediting_750034 | chr19_3961987_- | SINE | Alu | Name=AluY |
| ADediting_750035 | chr19_3961991_- | SINE | Alu | Name=AluY |
| ADediting_750036 | chr19_3961997_- | SINE | Alu | Name=AluY |
| ADediting_750037 | chr19_3962010_- | SINE | Alu | Name=AluY |
| ADediting_750038 | chr19_3962023_- | SINE | Alu | Name=AluY |
| ADediting_750039 | chr19_3962026_- | SINE | Alu | Name=AluY |
| ADediting_750040 | chr19_3962027_- | SINE | Alu | Name=AluY |
| ADediting_750041 | chr19_3962028_- | SINE | Alu | Name=AluY |
| ADediting_750042 | chr19_3962029_- | SINE | Alu | Name=AluY |
| ADediting_750043 | chr19_3962032_- | SINE | Alu | Name=AluY |
| ADediting_750044 | chr19_3962034_- | SINE | Alu | Name=AluY |
| ADediting_750045 | chr19_3962035_- | SINE | Alu | Name=AluY |
| ADediting_750046 | chr19_3962036_- | SINE | Alu | Name=AluY |
| ADediting_750047 | chr19_3962038_- | SINE | Alu | Name=AluY |
| ADediting_750048 | chr19_3962041_- | SINE | Alu | Name=AluY |
| ADediting_750049 | chr19_3962052_- | SINE | Alu | Name=AluY |
| ADediting_750050 | chr19_3962053_- | SINE | Alu | Name=AluY |
| ADediting_750051 | chr19_3962054_- | SINE | Alu | Name=AluY |
| ADediting_750052 | chr19_3962057_- | SINE | Alu | Name=AluY |
| ADediting_750053 | chr19_3962060_- | SINE | Alu | Name=AluY |
| ADediting_750054 | chr19_3962062_- | SINE | Alu | Name=AluY |
| ADediting_750055 | chr19_3962086_- | SINE | Alu | Name=AluY |
| ADediting_750056 | chr19_3962091_- | SINE | Alu | Name=AluY |
| ADediting_750057 | chr19_3962094_- | SINE | Alu | Name=AluY |
| ADediting_750058 | chr19_3962099_- | SINE | Alu | Name=AluY |
| ADediting_750059 | chr19_3962113_- | SINE | Alu | Name=AluY |
| ADediting_750060 | chr19_3962121_- | SINE | Alu | Name=AluY |
| ADediting_750061 | chr19_3962129_- | SINE | Alu | Name=AluY |
| ADediting_750062 | chr19_3962130_- | SINE | Alu | Name=AluY |
| ADediting_750063 | chr19_3962138_- | SINE | Alu | Name=AluY |
| ADediting_750064 | chr19_3962145_- | SINE | Alu | Name=AluY |
| ADediting_750065 | chr19_3962519_- | SINE | Alu | Name=AluSq2 |
| ADediting_750066 | chr19_3962530_- | SINE | Alu | Name=AluSq2 |
| ADediting_750067 | chr19_3962533_- | SINE | Alu | Name=AluSq2 |
| ADediting_750068 | chr19_3962593_- | SINE | Alu | Name=AluSq2 |
| ADediting_750069 | chr19_3962610_- | SINE | Alu | Name=AluSq2 |
| ADediting_750070 | chr19_3962613_- | SINE | Alu | Name=AluSq2 |
| ADediting_750071 | chr19_3962619_- | SINE | Alu | Name=AluSq2 |
| ADediting_750072 | chr19_3962628_- | SINE | Alu | Name=AluSq2 |
| ADediting_750073 | chr19_3962629_- | SINE | Alu | Name=AluSq2 |
| ADediting_750074 | chr19_3962642_- | SINE | Alu | Name=AluSq2 |
| ADediting_750075 | chr19_3962653_- | SINE | Alu | Name=AluSq2 |
| ADediting_750076 | chr19_3962655_- | SINE | Alu | Name=AluSq2 |
| ADediting_750077 | chr19_3962665_- | SINE | Alu | Name=AluSq2 |
| ADediting_750078 | chr19_3962668_- | SINE | Alu | Name=AluSq2 |
| ADediting_750079 | chr19_3962669_- | SINE | Alu | Name=AluSq2 |
| ADediting_750080 | chr19_3962677_- | SINE | Alu | Name=AluSq2 |
| ADediting_750081 | chr19_3962684_- | SINE | Alu | Name=AluSq2 |
| ADediting_750082 | chr19_3962694_- | SINE | Alu | Name=AluSq2 |
| ADediting_750083 | chr19_3962695_- | SINE | Alu | Name=AluSq2 |
| ADediting_750084 | chr19_3962720_- | SINE | Alu | Name=AluSq2 |
| ADediting_750085 | chr19_3962731_- | SINE | Alu | Name=AluSq2 |
| ADediting_750086 | chr19_3962761_- | SINE | Alu | Name=AluSq2 |
| ADediting_750087 | chr19_3962782_- | SINE | Alu | Name=AluSq2 |
| ADediting_750088 | chr19_3962844_- | SINE | Alu | Name=AluSq |
| ADediting_750089 | chr19_3962856_- | SINE | Alu | Name=AluSq |
| ADediting_750090 | chr19_3962857_- | SINE | Alu | Name=AluSq |
| ADediting_750091 | chr19_3962919_- | SINE | Alu | Name=AluSq |
| ADediting_750092 | chr19_3962939_- | SINE | Alu | Name=AluSq |
| ADediting_750093 | chr19_3962953_- | SINE | Alu | Name=AluSq |
| ADediting_750094 | chr19_3962967_- | SINE | Alu | Name=AluSq |
| ADediting_750095 | chr19_3962970_- | SINE | Alu | Name=AluSq |
| ADediting_750096 | chr19_3962990_- | SINE | Alu | Name=AluSq |
| ADediting_750097 | chr19_3963002_- | SINE | Alu | Name=AluSq |
| ADediting_750098 | chr19_3963015_- | SINE | Alu | Name=AluSq |
| ADediting_750099 | chr19_3963019_- | SINE | Alu | Name=AluSq |
| ADediting_750100 | chr19_3963020_- | SINE | Alu | Name=AluSq |
| ADediting_750101 | chr19_3963026_- | SINE | Alu | Name=AluSq |
| ADediting_750102 | chr19_3963045_- | SINE | Alu | Name=AluSq |
| ADediting_750103 | chr19_3963053_- | SINE | Alu | Name=AluSq |
| ADediting_750104 | chr19_3963079_- | SINE | Alu | Name=AluSq |
| ADediting_750105 | chr19_3963178_- | SINE | Alu | Name=AluJb |
| ADediting_750106 | chr19_3963190_- | SINE | Alu | Name=AluJb |
| ADediting_750107 | chr19_3963197_- | SINE | Alu | Name=AluJb |
| ADediting_750108 | chr19_3963221_- | SINE | Alu | Name=AluJb |
| ADediting_750109 | chr19_3963251_- | SINE | Alu | Name=AluJb |
| ADediting_750110 | chr19_3963261_- | SINE | Alu | Name=AluJb |
| ADediting_750112 | chr19_3965399_- | SINE | Alu | Name=AluSx1 |
| ADediting_750113 | chr19_3965425_- | SINE | Alu | Name=AluSx1 |
| ADediting_750114 | chr19_3965434_- | SINE | Alu | Name=AluSx1 |
| ADediting_750115 | chr19_3965437_- | SINE | Alu | Name=AluSx1 |
| ADediting_750116 | chr19_3965496_- | SINE | Alu | Name=AluSx1 |
| ADediting_750117 | chr19_3965506_- | SINE | Alu | Name=AluSx1 |
| ADediting_750118 | chr19_3965509_- | SINE | Alu | Name=AluSx1 |
| ADediting_750119 | chr19_3965535_- | SINE | Alu | Name=AluSx1 |
| ADediting_750120 | chr19_3965536_- | SINE | Alu | Name=AluSx1 |
| ADediting_750121 | chr19_3965555_- | SINE | Alu | Name=AluSx1 |
| ADediting_750122 | chr19_3965571_- | SINE | Alu | Name=AluSx1 |
| ADediting_750123 | chr19_3965700_- | SINE | Alu | Name=AluJb |
| ADediting_750124 | chr19_3965703_- | SINE | Alu | Name=AluJb |
| ADediting_750125 | chr19_3965757_- | SINE | Alu | Name=AluJb |
| ADediting_750126 | chr19_3965762_- | SINE | Alu | Name=AluJb |
| ADediting_750127 | chr19_3965788_- | SINE | Alu | Name=AluJb |
| ADediting_750128 | chr19_3965797_- | SINE | Alu | Name=AluJb |
| ADediting_750129 | chr19_3965803_- | SINE | Alu | Name=AluJb |
| ADediting_750130 | chr19_3965865_- | SINE | Alu | Name=AluJb |
| ADediting_750131 | chr19_3965927_- | SINE | Alu | Name=AluJb |
| ADediting_750132 | chr19_3965940_- | SINE | Alu | Name=AluJr |
| ADediting_750133 | chr19_3965980_- | SINE | Alu | Name=AluJr |
| ADediting_750134 | chr19_3965981_- | SINE | Alu | Name=AluJr |
| ADediting_750135 | chr19_3966002_- | SINE | Alu | Name=AluJr |
| ADediting_750136 | chr19_3966012_- | SINE | Alu | Name=AluJr |
| ADediting_750137 | chr19_3966017_- | SINE | Alu | Name=AluJr |
| ADediting_750139 | chr19_3967655_- | SINE | Alu | Name=AluSx1 |
| ADediting_750140 | chr19_3968047_- | SINE | Alu | Name=FLAM_C |
| ADediting_750141 | chr19_3968055_- | SINE | Alu | Name=FLAM_C |
| ADediting_750142 | chr19_3968238_- | SINE | Alu | Name=AluSx1 |
| ADediting_750143 | chr19_3968250_- | SINE | Alu | Name=AluSx1 |
| ADediting_750144 | chr19_3968251_- | SINE | Alu | Name=AluSx1 |
| ADediting_750145 | chr19_3968320_- | SINE | Alu | Name=AluSx1 |
| ADediting_750146 | chr19_3968373_- | SINE | Alu | Name=AluSx1 |
| ADediting_750147 | chr19_3968395_- | SINE | Alu | Name=AluSx1 |
| ADediting_750148 | chr19_3968433_- | SINE | Alu | Name=AluSx1 |
| ADediting_750149 | chr19_3969259_- | SINE | Alu | Name=AluJr |
| ADediting_750150 | chr19_3969264_- | SINE | Alu | Name=AluJr |
| ADediting_750151 | chr19_3969277_- | SINE | Alu | Name=AluJr |
| ADediting_750152 | chr19_3969290_- | SINE | Alu | Name=AluJr |
| ADediting_1555969 | chr19_3960722_- | SINE | Alu | Name=AluSx1 |
| ADediting_1555970 | chr19_3961948_- | SINE | Alu | Name=AluY |
| ADediting_1555971 | chr19_3962049_- | SINE | Alu | Name=AluY |
| ADediting_1555972 | chr19_3962107_- | SINE | Alu | Name=AluY |
| ADediting_1555973 | chr19_3962124_- | SINE | Alu | Name=AluY |
| ADediting_1555974 | chr19_3962566_- | SINE | Alu | Name=AluSq2 |
| ADediting_1555975 | chr19_3962780_- | SINE | Alu | Name=AluSq2 |
| ADediting_1555976 | chr19_3962858_- | SINE | Alu | Name=AluSq |
| ADediting_1555977 | chr19_3962909_- | SINE | Alu | Name=AluSq |
| ADediting_1555978 | chr19_3962936_- | SINE | Alu | Name=AluSq |
| ADediting_1555979 | chr19_3962945_- | SINE | Alu | Name=AluSq |
| ADediting_1555980 | chr19_3965726_- | SINE | Alu | Name=AluJb |
| ADediting_1555981 | chr19_3965776_- | SINE | Alu | Name=AluJb |
| ADediting_1555982 | chr19_3966050_- | SINE | Alu | Name=AluJr |
| ADediting_1555983 | chr19_3967252_- | SINE | Alu | Name=AluSx3 |
| ADediting_1555984 | chr19_3968079_- | SINE | Alu | Name=FLAM_C |
Top |
RNA A-to-I editing events in the alternative splicing sites for DAPK3 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for DAPK3 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for DAPK3 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for DAPK3 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_107020 | chr1_37500952_- | ENSG00000167657.14 | ENST00000301264.7 | DAPK3-201 | hsa-miR-5581-3p | chr19 | 3958730 | 3958736 | 7mer-m8 | 3958729 | 3958753 | 146 | -20.49 |
| ADediting_107020 | chr1_37500952_- | ENSG00000167657.14 | ENST00000545797.7 | DAPK3-202 | hsa-miR-5581-3p | chr19 | 3958730 | 3958736 | 7mer-m8 | 3958729 | 3958753 | 146 | -20.49 |
| ADediting_496066 | chr15_66496985_- | ENSG00000167657.14 | ENST00000301264.7 | DAPK3-201 | hsa-miR-4512 | chr19 | 3959076 | 3959083 | 8mer-1a | 3959076 | 3959100 | 146 | -25.39 |
| ADediting_496066 | chr15_66496985_- | ENSG00000167657.14 | ENST00000545797.7 | DAPK3-202 | hsa-miR-4512 | chr19 | 3959076 | 3959083 | 8mer-1a | 3959076 | 3959100 | 146 | -25.39 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| Differentially expressed gene-miRNA network |
Top |
The effects of the RNA editing to the stability of the RNA structures for DAPK3 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
Top |
Relation with ADAR for DAPK3 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_750028 | chr19_3961951_- | 0.0538323706996296 | 0.109626017519478 | 0.680087597982862 | 0.0235112847054224 | 1.57605772619254e-09 | 0.33428131625336 |
| CER | ADediting_750028 | chr19_3961951_- | 0.00390346051752438 | 0.2343004713907 | 5.00456892844897e-05 | 0.3248163718187 | 0.0326942808533276 | 0.17450821306032 |
| CER | ADediting_750034 | chr19_3961987_- | 0.0479814980557493 | 0.161753058997217 | 0.000100389141868134 | 0.312223695453852 | 0.0418647609698717 | 0.166377748155673 |
| DLPFC | ADediting_750038 | chr19_3962023_- | 2.41765463901622e-07 | 0.288211273765167 | 3.03671302789578e-09 | 0.328702669886166 | 0.000684027260449312 | 0.191854584222067 |
| CER | ADediting_750038 | chr19_3962023_- | 3.34464499993004e-05 | 0.331860373447802 | 2.52808009261171e-08 | 0.435614472473771 | 0.097926071930028 | 0.135638991076612 |
| CER | ADediting_750039 | chr19_3962026_- | 1.90497192028776e-05 | 0.341420377828952 | 4.44359237746577e-10 | 0.481498936242417 | 0.0308693148070114 | 0.176352874265734 |
| TCX | ADediting_750039 | chr19_3962026_- | 0.0857581602388792 | 0.140769477161687 | 6.90597989680283e-06 | 0.357900907068709 | 0.199040380022385 | -0.105451389786737 |
| DLPFC | ADediting_750052 | chr19_3962057_- | 7.90844076084307e-15 | 0.422159146644443 | 1.26115401343055e-15 | 0.433385704868198 | 0.0167160570280262 | 0.135825563898212 |
| DLPFC | ADediting_750055 | chr19_3962086_- | 1.13402233234265e-07 | 0.295669732118401 | 1.92522200117738e-09 | 0.332590995300496 | 0.0473434525410795 | 0.112735127733529 |
| DLPFC | ADediting_750058 | chr19_3962099_- | 3.09376794018257e-08 | 0.307994272983649 | 1.25854569609537e-13 | 0.404405284495222 | 0.475490115778672 | 0.0406758723010701 |
| CER | ADediting_750058 | chr19_3962099_- | 0.00137618272165933 | 0.258941875883214 | 9.22339240014824e-07 | 0.388122866525248 | 0.485005671955344 | 0.0574473217450481 |
| TCX | ADediting_750058 | chr19_3962099_- | 0.0398271548705702 | 0.168044233152988 | 2.91247100286426e-06 | 0.371236271340031 | 0.158353275290936 | -0.115758380100872 |
| DLPFC | ADediting_750061 | chr19_3962129_- | 7.03656482940549e-08 | 0.300264662409884 | 5.00941301848617e-16 | 0.43887813127566 | 0.115880327980402 | 0.0894830618603712 |
| DLPFC | ADediting_750062 | chr19_3962130_- | 1.14069040851664e-07 | 0.295612781391882 | 2.14925276670241e-16 | 0.443826126702276 | 0.116477484308778 | 0.0893373316808999 |
| DLPFC | ADediting_750063 | chr19_3962138_- | 6.66682936115055e-09 | 0.321861814479551 | 8.14299355574559e-15 | 0.42197700420039 | 0.0152576962201259 | 0.137698364977928 |
| DLPFC | ADediting_750065 | chr19_3962519_- | 7.06803236742384e-10 | 0.340954168835511 | 3.34921148848461e-16 | 0.441242279105108 | 0.0209380106847759 | 0.1311111288706 |
| CER | ADediting_750065 | chr19_3962519_- | 0.00374475326207964 | 0.235329308636162 | 0.000100277342892539 | 0.312244306751787 | 0.0864646619681973 | 0.14045622363275 |
| DLPFC | ADediting_750066 | chr19_3962530_- | 1.67372271955676e-05 | 0.241817445113873 | 3.31846982979462e-08 | 0.307343422269047 | 0.375900832574607 | 0.0504633752218123 |
| CER | ADediting_750066 | chr19_3962530_- | 0.000265312402123354 | 0.293641337990991 | 2.79148093982098e-07 | 0.404732346309076 | 0.746052065537362 | -0.0266605177936192 |
| DLPFC | ADediting_750068 | chr19_3962593_- | 9.12850529305836e-11 | 0.357302506391249 | 3.01727944679729e-11 | 0.365769932305348 | 0.00365439237278737 | 0.164618264755287 |
| TCX | ADediting_750073 | chr19_3962629_- | 0.0103281156656115 | 0.2088353006581 | 0.593555846954861 | 0.0439220174787967 | 4.5653189713514e-07 | 0.398005271321521 |
| CER | ADediting_750074 | chr19_3962642_- | 0.0130027385322043 | 0.202382733765159 | 3.57776799296103e-05 | 0.330694586401309 | 0.814357457401656 | -0.0193319535350742 |
| DLPFC | ADediting_750076 | chr19_3962655_- | 1.20408724466986e-07 | 0.29508678984829 | 2.02339681932302e-08 | 0.311902453930319 | 0.0426983646250323 | 0.115187830841968 |
| CER | ADediting_750076 | chr19_3962655_- | 0.000601228287986402 | 0.276960980657719 | 7.00079998689686e-07 | 0.392035709867335 | 0.221303221663826 | 0.100450774057402 |
| CER | ADediting_750077 | chr19_3962665_- | 0.000217216540798941 | 0.297568807759631 | 1.40319534375118e-07 | 0.413897490795987 | 0.640867060718545 | 0.0383956384641861 |
| DLPFC | ADediting_750079 | chr19_3962669_- | 6.0966477992613e-06 | 0.253699461988857 | 1.34662118965398e-09 | 0.335603062144193 | 0.0102602932658671 | 0.145602358711178 |
| CER | ADediting_750079 | chr19_3962669_- | 0.000822703873370736 | 0.270280971747932 | 2.97586651670001e-08 | 0.433612563861485 | 0.0747835683927416 | 0.145923455426726 |
| CER | ADediting_750080 | chr19_3962677_- | 0.0411416238003171 | 0.166961228829482 | 7.91340795084934e-05 | 0.316590628140111 | 0.301734602701656 | 0.0848790729102743 |
| DLPFC | ADediting_750082 | chr19_3962694_- | 2.8916940168221e-05 | 0.235123882855377 | 1.47757201151493e-10 | 0.353539609536933 | 0.00984443197623006 | 0.146405594766056 |
| CER | ADediting_750088 | chr19_3962844_- | 0.00789669207575392 | 0.216136793544362 | 5.43994588766818e-05 | 0.32333642050363 | 0.290590944409217 | 0.0868528791501263 |
| TCX | ADediting_750091 | chr19_3962919_- | 0.51993015627135 | 0.0529437569213295 | 0.610217387739467 | -0.0419546248911293 | 2.4658072135174e-05 | 0.337076766206166 |
| CER | ADediting_750092 | chr19_3962939_- | 7.64197827156178e-05 | 0.317225632503693 | 3.53857028965569e-11 | 0.507118345248305 | 0.0462914845394396 | 0.162979219278187 |
| CER | ADediting_750093 | chr19_3962953_- | 0.000374736355151651 | 0.286725242968394 | 1.90884106955293e-07 | 0.409830616198479 | 0.0219611676405707 | 0.186973855593387 |
| CER | ADediting_750094 | chr19_3962967_- | 0.00098600465224031 | 0.266346084534013 | 5.12534826465005e-08 | 0.426843428522631 | 0.108950644218411 | 0.131409584365005 |
| CER | ADediting_750095 | chr19_3962970_- | 0.0140968478162421 | 0.200075254718769 | 1.75518715763519e-06 | 0.378790396607793 | 0.0910298020246833 | 0.138479939209194 |
| TCX | ADediting_750095 | chr19_3962970_- | 0.904553531377251 | 0.0098730587735165 | 0.000135619613184233 | 0.306603604057638 | 0.697182027136299 | -0.0320319117287771 |
| CER | ADediting_750099 | chr19_3963019_- | 0.000137564186343352 | 0.306334794798871 | 1.28343154572929e-07 | 0.415066483074703 | 0.0015936873311984 | 0.255614936788721 |
| DLPFC | ADediting_750100 | chr19_3963020_- | 3.50177081737252e-06 | 0.259980752337233 | 1.54263094538427e-08 | 0.314370051761576 | 0.000906810674139943 | 0.187529838168528 |
| CER | ADediting_750100 | chr19_3963020_- | 0.00864078906106809 | 0.213712608838402 | 2.29022171623522e-06 | 0.374845183977789 | 0.0589948812411511 | 0.15453872903215 |
| CER | ADediting_750101 | chr19_3963026_- | 0.00011628008307613 | 0.309492214072701 | 2.30441768064067e-08 | 0.436745887748834 | 0.00683103373322237 | 0.219987904873652 |
| DLPFC | ADediting_750103 | chr19_3963053_- | 3.20977468099275e-07 | 0.285362980505487 | 3.39440911776272e-08 | 0.307133053296563 | 0.0101801046949061 | 0.145754969382556 |
| CER | ADediting_750105 | chr19_3963178_- | 0.0216745010926148 | 0.187373487782902 | 6.56644616219074e-08 | 0.42370852881505 | 0.138993177124038 | 0.121373073715888 |
| TCX | ADediting_750105 | chr19_3963178_- | 0.0462798044549389 | 0.162987822400534 | 1.24813724321035e-05 | 0.348400511359654 | 0.806009395723763 | 0.0202183961088896 |
| CER | ADediting_750107 | chr19_3963197_- | 0.0233132536583211 | 0.185147413134924 | 3.7176057064604e-06 | 0.367526418327467 | 0.00596373349183734 | 0.223539304866671 |
| DLPFC | ADediting_750111 | chr19_3963378_- | 3.84859352392067e-09 | 0.326659364938274 | 1.64786433180524e-11 | 0.370293620584772 | 0.163220763583784 | 0.0793877661144653 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 8.19688081492626e-32 | 0.600908617094136 | 1.04068581229032e-26 | 0.557456491020506 | 1.36913932852987e-29 | 0.582777227485562 |
| AC | 2.77736927957654e-71 | 0.850890435070626 | 1.38527735702888e-50 | 0.771356254197787 | 5.0447387572996e-17 | 0.497303871992354 |
| PCC | 2.06175497129393e-71 | 0.903371356072177 | 6.97171734851488e-82 | 0.92599104982367 | 0.0414813589218133 | 0.147673767011881 |
| CER | 5.92560340319354e-13 | 0.544483561845053 | 4.12539289862562e-27 | 0.738459145209203 | 0.00431518474689456 | 0.231797030482499 |
| TCX | 3.82975406408728e-30 | 0.765547894342573 | 3.89417189954701e-25 | 0.718802009742453 | 0.154945719643086 | 0.116707542185756 |
| FP | 5.63963669798209e-18 | 0.588564714220915 | 2.18388076868243e-18 | 0.59442933355259 | 0.0189889872599921 | 0.17568913537959 |
| IFG | 1.03304184967859e-07 | 0.845547272395908 | 8.06697959178191e-07 | 0.812540176906898 | 0.267610471583605 | 0.230515363425613 |
| STG | 1.11688856307707e-13 | 0.701124323223977 | 3.95887777240385e-12 | 0.667813115879403 | 0.47985697864695 | -0.0781419028441849 |
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Relation with AD stages for DAPK3 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_750031 | chr19_3961959_- | 0.000400015076067147 | 0.334660632411822 |
| CER | ADediting_750076 | chr19_3962655_- | 0.00011225349535104 | 0.363120935766174 |
| CER | ADediting_750092 | chr19_3962939_- | 0.000342255091672482 | 0.338302190024597 |
| CER | ADediting_750093 | chr19_3962953_- | 3.6834764913587e-06 | 0.428667751695497 |
| CER | ADediting_750095 | chr19_3962970_- | 0.000367703415589325 | 0.336632953238485 |
| CER | ADediting_750099 | chr19_3963019_- | 0.000712249511998466 | 0.320785052134235 |
| CER | ADediting_750101 | chr19_3963026_- | 0.000123685812840966 | 0.361040910086108 |
| CER | ADediting_750107 | chr19_3963197_- | 0.000995339592171868 | 0.31242475516223 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 0.000148361394406792 | 0.357100738286608 |
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RelatedDrugs for DAPK3 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| DAPK3 | O43293 | DB12010 | Fostamatinib | Death-associated protein kinase 3 | small molecule | approved|investigational |
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RelatedDiseases for DAPK3 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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