|
||||||
|
 | |
| |
| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
| |
| |
| The effects of the RNA editing to the stability of the RNA structures |
| |
| |
| |
|
Gene summary for ZNF738 |
 Gene summary |
| Gene information | Gene symbol | ZNF738 | Gene ID | 148203 |
| Gene name | zinc finger protein 738 | |
| Synonyms | - | |
| Cytomap | 19p12 | |
| Type of gene | protein-coding | |
| Description | protein ZNF738 | |
| Modification date | 20200313 | |
| UniProtAcc | Q8NE65, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for ZNF738 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_730308(21364885, +), ADediting_730309(21364887, +), ADediting_730310(21376609, +), ADediting_730311(21376610, +), ADediting_730312(21376617, +), ADediting_730313(21376657, +), ADediting_730314(21376671, +), ADediting_730315(21376674, +), ADediting_730316(21376694, +), ADediting_730317(21376786, +), ADediting_730318(21376798, +), ADediting_730319(21376814, +), ADediting_730320(21377052, +), ADediting_730321(21377053, +), ADediting_730322(21377173, +), ADediting_730323(21377176, +), ADediting_730324(21377186, +), ADediting_730325(21377192, +), ADediting_730326(21377196, +), ADediting_730327(21377200, +), ADediting_730328(21377203, +), ADediting_730329(21377267, +), ADediting_730330(21377290, +), ADediting_730331(21378703, +), ADediting_730332(21378712, +), ADediting_730333(21378808, +), ADediting_730334(21378813, +), ADediting_730335(21378851, +), ADediting_730336(21378861, +), ADediting_730337(21378876, +), ADediting_1554205(21376608, +), ADediting_1554206(21376785, +), ADediting_1554207(21376807, +), ADediting_1554208(21377213, +), ADediting_1554209(21377216, +), ADediting_1554210(21377277, +), ADediting_1554211(21377296, +), ADediting_1554212(21378842, +), ADediting_1554213(21378846, +), |
Top |
RNA editing positional annotations for ZNF738 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_730308 | chr19_21364885_+ | intronic |
| ADediting_730309 | chr19_21364887_+ | intronic |
| ADediting_730310 | chr19_21376609_+ | intronic |
| ADediting_730311 | chr19_21376610_+ | intronic |
| ADediting_730312 | chr19_21376617_+ | intronic |
| ADediting_730313 | chr19_21376657_+ | intronic |
| ADediting_730314 | chr19_21376671_+ | intronic |
| ADediting_730315 | chr19_21376674_+ | intronic |
| ADediting_730316 | chr19_21376694_+ | intronic |
| ADediting_730317 | chr19_21376786_+ | intronic |
| ADediting_730318 | chr19_21376798_+ | intronic |
| ADediting_730319 | chr19_21376814_+ | intronic |
| ADediting_730320 | chr19_21377052_+ | intronic |
| ADediting_730321 | chr19_21377053_+ | intronic |
| ADediting_730322 | chr19_21377173_+ | intronic |
| ADediting_730323 | chr19_21377176_+ | intronic |
| ADediting_730324 | chr19_21377186_+ | intronic |
| ADediting_730325 | chr19_21377192_+ | intronic |
| ADediting_730326 | chr19_21377196_+ | intronic |
| ADediting_730327 | chr19_21377200_+ | intronic |
| ADediting_730328 | chr19_21377203_+ | intronic |
| ADediting_730329 | chr19_21377267_+ | intronic |
| ADediting_730330 | chr19_21377290_+ | intronic |
| ADediting_730331 | chr19_21378703_+ | UTR3 |
| ADediting_730332 | chr19_21378712_+ | UTR3 |
| ADediting_730333 | chr19_21378808_+ | UTR3 |
| ADediting_730334 | chr19_21378813_+ | UTR3 |
| ADediting_730335 | chr19_21378851_+ | UTR3 |
| ADediting_730336 | chr19_21378861_+ | UTR3 |
| ADediting_730337 | chr19_21378876_+ | UTR3 |
| ADediting_1554205 | chr19_21376608_+ | intronic |
| ADediting_1554206 | chr19_21376785_+ | intronic |
| ADediting_1554207 | chr19_21376807_+ | intronic |
| ADediting_1554208 | chr19_21377213_+ | intronic |
| ADediting_1554209 | chr19_21377216_+ | intronic |
| ADediting_1554210 | chr19_21377277_+ | intronic |
| ADediting_1554211 | chr19_21377296_+ | intronic |
| ADediting_1554212 | chr19_21378842_+ | UTR3 |
| ADediting_1554213 | chr19_21378846_+ | UTR3 |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_730308 | chr19_21364885_+ | SINE | Alu | Name=AluSc |
| ADediting_730309 | chr19_21364887_+ | SINE | Alu | Name=AluSc |
| ADediting_730310 | chr19_21376609_+ | SINE | Alu | Name=AluSp |
| ADediting_730311 | chr19_21376610_+ | SINE | Alu | Name=AluSp |
| ADediting_730312 | chr19_21376617_+ | SINE | Alu | Name=AluSp |
| ADediting_730313 | chr19_21376657_+ | SINE | Alu | Name=AluSp |
| ADediting_730314 | chr19_21376671_+ | SINE | Alu | Name=AluSp |
| ADediting_730315 | chr19_21376674_+ | SINE | Alu | Name=AluSp |
| ADediting_730316 | chr19_21376694_+ | SINE | Alu | Name=AluSp |
| ADediting_730317 | chr19_21376786_+ | SINE | Alu | Name=AluSp |
| ADediting_730318 | chr19_21376798_+ | SINE | Alu | Name=AluSp |
| ADediting_730319 | chr19_21376814_+ | SINE | Alu | Name=AluSp |
| ADediting_730320 | chr19_21377052_+ | SINE | Alu | Name=AluSp |
| ADediting_730321 | chr19_21377053_+ | SINE | Alu | Name=AluSp |
| ADediting_730322 | chr19_21377173_+ | SINE | Alu | Name=AluSp |
| ADediting_730323 | chr19_21377176_+ | SINE | Alu | Name=AluSp |
| ADediting_730324 | chr19_21377186_+ | SINE | Alu | Name=AluSp |
| ADediting_730325 | chr19_21377192_+ | SINE | Alu | Name=AluSp |
| ADediting_730326 | chr19_21377196_+ | SINE | Alu | Name=AluSp |
| ADediting_730327 | chr19_21377200_+ | SINE | Alu | Name=AluSp |
| ADediting_730328 | chr19_21377203_+ | SINE | Alu | Name=AluSp |
| ADediting_730329 | chr19_21377267_+ | SINE | Alu | Name=AluSp |
| ADediting_730330 | chr19_21377290_+ | SINE | Alu | Name=AluSp |
| ADediting_730331 | chr19_21378703_+ | SINE | Alu | Name=AluSp |
| ADediting_730332 | chr19_21378712_+ | SINE | Alu | Name=AluSp |
| ADediting_730333 | chr19_21378808_+ | SINE | Alu | Name=AluSp |
| ADediting_730334 | chr19_21378813_+ | SINE | Alu | Name=AluSp |
| ADediting_730335 | chr19_21378851_+ | SINE | Alu | Name=AluSp |
| ADediting_730336 | chr19_21378861_+ | SINE | Alu | Name=AluSp |
| ADediting_730337 | chr19_21378876_+ | SINE | Alu | Name=AluSp |
| ADediting_1554205 | chr19_21376608_+ | SINE | Alu | Name=AluSp |
| ADediting_1554206 | chr19_21376785_+ | SINE | Alu | Name=AluSp |
| ADediting_1554207 | chr19_21376807_+ | SINE | Alu | Name=AluSp |
| ADediting_1554208 | chr19_21377213_+ | SINE | Alu | Name=AluSp |
| ADediting_1554209 | chr19_21377216_+ | SINE | Alu | Name=AluSp |
| ADediting_1554210 | chr19_21377277_+ | SINE | Alu | Name=AluSp |
| ADediting_1554211 | chr19_21377296_+ | SINE | Alu | Name=AluSp |
| ADediting_1554212 | chr19_21378842_+ | SINE | Alu | Name=AluSp |
| ADediting_1554213 | chr19_21378846_+ | SINE | Alu | Name=AluSp |
Top |
RNA A-to-I editing events in the alternative splicing sites for ZNF738 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZNF738 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
 | |
 | |
| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for ZNF738 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for ZNF738 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1554212 | chr19_21378842_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-6729-5p | chr19 | 21378839 | 21378845 | 7mer-1a | 21378825 | 21378845 | 140 | -29.26 |
| ADediting_1554212 | chr19_21378842_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-6729-5p | chr19 | 21378839 | 21378845 | 7mer-1a | 21378825 | 21378845 | 140 | -29.26 |
| ADediting_1554213 | chr19_21378846_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-6765-5p | chr19 | 21378844 | 21378850 | 7mer-m8 | 21378827 | 21378851 | 150 | -30.48 |
| ADediting_1554213 | chr19_21378846_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-6765-5p | chr19 | 21378844 | 21378850 | 7mer-m8 | 21378827 | 21378851 | 150 | -30.48 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-1827 | chr19 | 21378709 | 21378716 | 8mer-1a | 21378698 | 21378716 | 154 | -20.82 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-4722-5p | chr19 | 21378706 | 21378712 | 7mer-m8 | 21378691 | 21378713 | 158 | -30.22 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-4768-3p | chr19 | 21378705 | 21378711 | 7mer-m8 | 21378693 | 21378712 | 142 | -12.24 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-6808-5p | chr19 | 21378708 | 21378714 | 7mer-m8 | 21378690 | 21378715 | 153 | -25.51 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-6893-5p | chr19 | 21378708 | 21378714 | 7mer-m8 | 21378694 | 21378715 | 146 | -16.48 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-940 | chr19 | 21378708 | 21378714 | 7mer-m8 | 21378695 | 21378715 | 149 | -16.78 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-1827 | chr19 | 21378709 | 21378716 | 8mer-1a | 21378698 | 21378716 | 154 | -20.82 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-4722-5p | chr19 | 21378706 | 21378712 | 7mer-m8 | 21378691 | 21378713 | 158 | -30.22 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-4768-3p | chr19 | 21378705 | 21378711 | 7mer-m8 | 21378693 | 21378712 | 142 | -12.24 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-6808-5p | chr19 | 21378708 | 21378714 | 7mer-m8 | 21378690 | 21378715 | 153 | -25.51 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-6893-5p | chr19 | 21378708 | 21378714 | 7mer-m8 | 21378694 | 21378715 | 146 | -16.48 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-940 | chr19 | 21378708 | 21378714 | 7mer-m8 | 21378695 | 21378715 | 149 | -16.78 |
| ADediting_730334 | chr19_21378813_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-4786-5p | chr19 | 21378811 | 21378817 | 7mer-m8 | 21378793 | 21378818 | 154 | -25.28 |
| ADediting_730334 | chr19_21378813_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-6849-3p | chr19 | 21378807 | 21378813 | 7mer-m8 | 21378794 | 21378814 | 152 | -21.45 |
| ADediting_730334 | chr19_21378813_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-4786-5p | chr19 | 21378811 | 21378817 | 7mer-m8 | 21378793 | 21378818 | 154 | -25.28 |
| ADediting_730334 | chr19_21378813_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-6849-3p | chr19 | 21378807 | 21378813 | 7mer-m8 | 21378794 | 21378814 | 152 | -21.45 |
| ADediting_730336 | chr19_21378861_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-3189-3p | chr19 | 21378855 | 21378861 | 7mer-m8 | 21378839 | 21378862 | 157 | -25.36 |
| ADediting_730336 | chr19_21378861_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-6813-3p | chr19 | 21378856 | 21378862 | 7mer-m8 | 21378843 | 21378863 | 140 | -10.68 |
| ADediting_730336 | chr19_21378861_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-3189-3p | chr19 | 21378855 | 21378861 | 7mer-m8 | 21378839 | 21378862 | 157 | -25.36 |
| ADediting_730336 | chr19_21378861_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-6813-3p | chr19 | 21378856 | 21378862 | 7mer-m8 | 21378843 | 21378863 | 140 | -10.68 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1554212 | chr19_21378842_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-1262 | chr19 | 21378839 | 21378845 | 7mer-m8 | 21378825 | 21378846 | 155 | -18.44 |
| ADediting_1554212 | chr19_21378842_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-4701-3p | chr19 | 21378839 | 21378845 | 7mer-m8 | 21378825 | 21378846 | 145 | -15.82 |
| ADediting_1554212 | chr19_21378842_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-6748-5p | chr19 | 21378840 | 21378846 | 7mer-m8 | 21378828 | 21378847 | 149 | -19.55 |
| ADediting_1554212 | chr19_21378842_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-1262 | chr19 | 21378839 | 21378845 | 7mer-m8 | 21378825 | 21378846 | 155 | -18.44 |
| ADediting_1554212 | chr19_21378842_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-4701-3p | chr19 | 21378839 | 21378845 | 7mer-m8 | 21378825 | 21378846 | 145 | -15.82 |
| ADediting_1554212 | chr19_21378842_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-6748-5p | chr19 | 21378840 | 21378846 | 7mer-m8 | 21378828 | 21378847 | 149 | -19.55 |
| ADediting_1554213 | chr19_21378846_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-1262 | chr19 | 21378839 | 21378845 | 7mer-m8 | 21378825 | 21378846 | 155 | -18.44 |
| ADediting_1554213 | chr19_21378846_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-4701-3p | chr19 | 21378839 | 21378845 | 7mer-m8 | 21378825 | 21378846 | 145 | -15.82 |
| ADediting_1554213 | chr19_21378846_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-6134 | chr19 | 21378843 | 21378850 | 8mer-1a | 21378832 | 21378850 | 150 | -17.47 |
| ADediting_1554213 | chr19_21378846_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-6748-5p | chr19 | 21378840 | 21378846 | 7mer-m8 | 21378828 | 21378847 | 149 | -19.55 |
| ADediting_1554213 | chr19_21378846_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-6769a-5p | chr19 | 21378841 | 21378847 | 7mer-m8 | 21378828 | 21378848 | 140 | -21.27 |
| ADediting_1554213 | chr19_21378846_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-6769b-5p | chr19 | 21378841 | 21378847 | 7mer-m8 | 21378825 | 21378848 | 148 | -24.08 |
| ADediting_1554213 | chr19_21378846_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-1262 | chr19 | 21378839 | 21378845 | 7mer-m8 | 21378825 | 21378846 | 155 | -18.44 |
| ADediting_1554213 | chr19_21378846_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-4701-3p | chr19 | 21378839 | 21378845 | 7mer-m8 | 21378825 | 21378846 | 145 | -15.82 |
| ADediting_1554213 | chr19_21378846_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-6134 | chr19 | 21378843 | 21378850 | 8mer-1a | 21378832 | 21378850 | 150 | -17.47 |
| ADediting_1554213 | chr19_21378846_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-6748-5p | chr19 | 21378840 | 21378846 | 7mer-m8 | 21378828 | 21378847 | 149 | -19.55 |
| ADediting_1554213 | chr19_21378846_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-6769a-5p | chr19 | 21378841 | 21378847 | 7mer-m8 | 21378828 | 21378848 | 140 | -21.27 |
| ADediting_1554213 | chr19_21378846_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-6769b-5p | chr19 | 21378841 | 21378847 | 7mer-m8 | 21378825 | 21378848 | 148 | -24.08 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-let-7a-5p | chr19 | 21378709 | 21378716 | 8mer-1a | 21378694 | 21378716 | 153 | -18.35 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-let-7g-5p | chr19 | 21378709 | 21378716 | 8mer-1a | 21378695 | 21378716 | 147 | -18.15 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-let-7i-5p | chr19 | 21378709 | 21378716 | 8mer-1a | 21378696 | 21378716 | 153 | -20.68 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-4458 | chr19 | 21378709 | 21378716 | 8mer-1a | 21378698 | 21378716 | 147 | -15.65 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-4500 | chr19 | 21378709 | 21378716 | 8mer-1a | 21378700 | 21378716 | 147 | -16 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-let-7a-5p | chr19 | 21378709 | 21378716 | 8mer-1a | 21378694 | 21378716 | 153 | -18.35 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-let-7g-5p | chr19 | 21378709 | 21378716 | 8mer-1a | 21378695 | 21378716 | 147 | -18.15 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-let-7i-5p | chr19 | 21378709 | 21378716 | 8mer-1a | 21378696 | 21378716 | 153 | -20.68 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-4458 | chr19 | 21378709 | 21378716 | 8mer-1a | 21378698 | 21378716 | 147 | -15.65 |
| ADediting_730332 | chr19_21378712_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-4500 | chr19 | 21378709 | 21378716 | 8mer-1a | 21378700 | 21378716 | 147 | -16 |
| ADediting_730333 | chr19_21378808_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-4293 | chr19 | 21378805 | 21378812 | 8mer-1a | 21378796 | 21378812 | 146 | -16.68 |
| ADediting_730333 | chr19_21378808_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-4293 | chr19 | 21378805 | 21378812 | 8mer-1a | 21378796 | 21378812 | 146 | -16.68 |
| ADediting_730335 | chr19_21378851_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-7160-5p | chr19 | 21378846 | 21378852 | 7mer-m8 | 21378836 | 21378853 | 148 | -19.76 |
| ADediting_730335 | chr19_21378851_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-7162-3p | chr19 | 21378845 | 21378851 | 7mer-m8 | 21378834 | 21378852 | 150 | -18.37 |
| ADediting_730335 | chr19_21378851_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-7160-5p | chr19 | 21378846 | 21378852 | 7mer-m8 | 21378836 | 21378853 | 148 | -19.76 |
| ADediting_730335 | chr19_21378851_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-7162-3p | chr19 | 21378845 | 21378851 | 7mer-m8 | 21378834 | 21378852 | 150 | -18.37 |
| ADediting_730337 | chr19_21378876_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-100-3p | chr19 | 21378873 | 21378879 | 7mer-m8 | 21378860 | 21378880 | 154 | -23.23 |
| ADediting_730337 | chr19_21378876_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-100-3p | chr19 | 21378873 | 21378879 | 7mer-m8 | 21378860 | 21378880 | 154 | -23.23 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000172687.13 | ENST00000594245.1 | ZNF738-203 | hsa-miR-589-3p | chr19 | 21372777 | 21372783 | 7mer-m8 | 21372760 | 21372784 | 147 | -16.86 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-589-5p | chr19 | 21377546 | 21377553 | 8mer-1a | 21377531 | 21377553 | 142 | -15.45 |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-381-3p | chr19 | 21377903 | 21377909 | 7mer-m8 | 21377888 | 21377910 | 149 | -13.04 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-641 | chr19 | 21377834 | 21377840 | 7mer-m8 | 21377814 | 21377841 | 148 | -16.45 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-5688 | chr19 | 21378438 | 21378444 | 7mer-m8 | 21378423 | 21378445 | 150 | -9.4 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-641 | chr19 | 21377577 | 21377583 | 7mer-m8 | 21377560 | 21377584 | 153 | -12.29 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-641 | chr19 | 21377577 | 21377583 | 7mer-m8 | 21377560 | 21377584 | 153 | -12.29 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000172687.13 | ENST00000311015.7 | ZNF738-201 | hsa-miR-4775 | chr19 | 21379190 | 21379197 | 8mer-1a | 21379176 | 21379197 | 140 | -4.61 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000172687.13 | ENST00000380870.8 | ZNF738-202 | hsa-miR-4775 | chr19 | 21379190 | 21379197 | 8mer-1a | 21379176 | 21379197 | 140 | -4.61 |
| Differentially expressed gene-miRNA network |
Top |
The effects of the RNA editing to the stability of the RNA structures for ZNF738 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000311015.7 | protein_coding |  |  |
| ENST00000380870.8 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_730331 | ENST00000311015.7 | chr19_21378703_+ | 1845 | -578.00 | -578.70 | -587.20 |
| ADediting_730332 | ENST00000311015.7 | chr19_21378712_+ | 1854 | -581.00 | -578.70 | -587.20 |
| ADediting_730333 | ENST00000311015.7 | chr19_21378808_+ | 1950 | -578.00 | -578.70 | -587.20 |
| ADediting_730334 | ENST00000311015.7 | chr19_21378813_+ | 1955 | -580.30 | -578.70 | -587.20 |
| ADediting_1554212 | ENST00000311015.7 | chr19_21378842_+ | 1984 | -579.00 | -578.70 | -587.20 |
| ADediting_1554213 | ENST00000311015.7 | chr19_21378846_+ | 1988 | -579.80 | -578.70 | -587.20 |
| ADediting_730335 | ENST00000311015.7 | chr19_21378851_+ | 1993 | -581.20 | -578.70 | -587.20 |
| ADediting_730336 | ENST00000311015.7 | chr19_21378861_+ | 2003 | -578.70 | -578.70 | -587.20 |
| ADediting_730337 | ENST00000311015.7 | chr19_21378876_+ | 2018 | -578.30 | -578.70 | -587.20 |
| ADediting_730331 | ENST00000380870.8 | chr19_21378703_+ | 543 | -299.50 | -298.00 | -310.00 |
| ADediting_730332 | ENST00000380870.8 | chr19_21378712_+ | 552 | -300.70 | -298.00 | -310.00 |
| ADediting_730333 | ENST00000380870.8 | chr19_21378808_+ | 648 | -298.30 | -298.00 | -310.00 |
| ADediting_730334 | ENST00000380870.8 | chr19_21378813_+ | 653 | -299.60 | -298.00 | -310.00 |
| ADediting_1554212 | ENST00000380870.8 | chr19_21378842_+ | 682 | -298.30 | -298.00 | -310.00 |
| ADediting_1554213 | ENST00000380870.8 | chr19_21378846_+ | 686 | -299.00 | -298.00 | -310.00 |
| ADediting_730335 | ENST00000380870.8 | chr19_21378851_+ | 691 | -302.50 | -298.00 | -310.00 |
| ADediting_730336 | ENST00000380870.8 | chr19_21378861_+ | 701 | -299.10 | -298.00 | -310.00 |
| ADediting_730337 | ENST00000380870.8 | chr19_21378876_+ | 716 | -298.90 | -298.00 | -310.00 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
Top |
Relation with ADAR for ZNF738 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_1554205 | chr19_21376608_+ | 0.00504220045555511 | 0.227858321413642 | 0.000131392827374471 | 0.307200515499039 | 0.0123524532878198 | 0.203836039576078 |
| DLPFC | ADediting_730310 | chr19_21376609_+ | 0.00248280325288932 | 0.17125350735606 | 0.591976072685243 | 0.0305576498345978 | 1.74190018181853e-18 | 0.470547793543511 |
| CER | ADediting_730310 | chr19_21376609_+ | 9.16940025722249e-08 | 0.419432953808721 | 9.79056598469618e-06 | 0.352335319691053 | 0.00510347757825881 | 0.227550068010355 |
| TCX | ADediting_730310 | chr19_21376609_+ | 0.00560202432394758 | 0.225158297860745 | 0.639415255967856 | 0.0385625734077611 | 2.59704713513608e-05 | 0.33619602351537 |
| DLPFC | ADediting_730311 | chr19_21376610_+ | 2.97002997306915e-05 | 0.234791646365923 | 0.0857638761244255 | 0.0977471015559922 | 3.10627430260468e-18 | 0.467458808967431 |
| CER | ADediting_730311 | chr19_21376610_+ | 3.3249308844007e-07 | 0.402357781855776 | 1.46401474569781e-05 | 0.34578638259733 | 0.0207996987220941 | 0.188621834371485 |
| TCX | ADediting_730311 | chr19_21376610_+ | 0.00508704157113268 | 0.227632422646868 | 0.551681041205975 | 0.048981958765786 | 3.88852029760517e-05 | 0.329246957397536 |
| CER | ADediting_730312 | chr19_21376617_+ | 0.000131643037501869 | 0.307164685296854 | 0.00425005597540707 | 0.232178351327761 | 0.0742024835369275 | 0.146212953323094 |
| DLPFC | ADediting_730313 | chr19_21376657_+ | 6.60776066606096e-05 | 0.224620833325632 | 0.052327456905059 | 0.110318073196304 | 2.69279356276862e-11 | 0.366626245247316 |
| DLPFC | ADediting_730315 | chr19_21376674_+ | 7.13342037392798e-05 | 0.223622738157398 | 0.131863618023019 | 0.0857688310152217 | 2.40767325353018e-15 | 0.429478910460533 |
| CER | ADediting_730315 | chr19_21376674_+ | 1.53318503519666e-05 | 0.345025537282452 | 0.000685275786819517 | 0.274194401883604 | 0.307544516706087 | 0.0838690386662849 |
| CER | ADediting_730318 | chr19_21376798_+ | 0.000240777441103289 | 0.295553726559678 | 1.50795858285199e-05 | 0.345299193893659 | 0.00115680814570484 | 0.262824478850386 |
| TCX | ADediting_730322 | chr19_21377173_+ | 0.420672192932126 | 0.0662306625690366 | 0.0772397266547196 | -0.144719510632252 | 1.52295106012562e-05 | 0.345136039514682 |
| DLPFC | ADediting_730323 | chr19_21377176_+ | 7.59768878504436e-06 | 0.251159932952714 | 0.00281616943022862 | 0.169116667164722 | 3.24795690614931e-08 | 0.30754296183099 |
| TCX | ADediting_730323 | chr19_21377176_+ | 0.189283542800206 | 0.107770733568178 | 0.293323718233816 | -0.086364258248016 | 5.54036198581507e-05 | 0.323010889939154 |
| TCX | ADediting_730327 | chr19_21377200_+ | 0.605267709239703 | 0.0425365563009711 | 0.0503426739559624 | -0.160098743014889 | 3.09401715723377e-06 | 0.37032145850233 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 1.84490161566332e-13 | 0.401866504260597 | 5.38294495262075e-05 | 0.227272247040705 | 8.12342916026465e-44 | 0.682368753012973 |
| AC | 1.69533943523516e-41 | 0.721659732862813 | 1.39388516881473e-24 | 0.587385738248752 | 1.13419391427643e-28 | 0.626585522222565 |
| PCC | 1.08659489277835e-29 | 0.702153479767492 | 4.95363260953076e-29 | 0.696318512498975 | 0.000318687887339548 | 0.257736587831472 |
| CER | 6.13721141084043e-33 | 0.787655893891582 | 2.25945662015104e-30 | 0.76745764046447 | 0.00847347084961207 | 0.214241130055477 |
| TCX | 7.2405651639961e-09 | 0.450548699524195 | 0.527810664199219 | 0.05194939693043 | 6.56816469545522e-16 | 0.597905553542112 |
| FP | 3.5671887233704e-12 | 0.490701349996588 | 8.25540587796594e-18 | 0.586175378654811 | 0.00200484665791917 | 0.23007508874326 |
| PG | 3.53405821214373e-27 | 0.685713550699772 | 8.66864629540106e-17 | 0.560650452276448 | 0.0898004990177807 | 0.124744417756614 |
| STG | 2.7785646408687e-12 | 0.671320314126934 | 1.56237884795499e-06 | 0.496480559404057 | 0.0015217392921281 | 0.340627183568291 |
Top |
Relation with AD stages for ZNF738 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 1.38926838337885e-06 | 0.445099622917553 |
Top |
RelatedDrugs for ZNF738 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for ZNF738 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|