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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for ZNF582 |
 Gene summary |
| Gene information | Gene symbol | ZNF582 | Gene ID | 147948 |
| Gene name | zinc finger protein 582 | |
| Synonyms | - | |
| Cytomap | 19q13.43 | |
| Type of gene | protein-coding | |
| Description | zinc finger protein 582 | |
| Modification date | 20200313 | |
| UniProtAcc | Q96NG8, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for ZNF582 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_783524(56379994, -), ADediting_783525(56380075, -), ADediting_783526(56380079, -), ADediting_783527(56380092, -), ADediting_783528(56380102, -), ADediting_783529(56380112, -), ADediting_783532(56383994, -), ADediting_783533(56384056, -), ADediting_783534(56384059, -), ADediting_783535(56384071, -), ADediting_783536(56384072, -), ADediting_783538(56384322, -), ADediting_783539(56384323, -), ADediting_783540(56384344, -), ADediting_783541(56384354, -), ADediting_783542(56384360, -), ADediting_783543(56384834, -), ADediting_783550(56388773, -), ADediting_783551(56388892, -), ADediting_1559184(56384074, -), ADediting_1559185(56384238, -), ADediting_1559186(56385482, -), ADediting_1559187(56385554, -), ADediting_1559188(56385617, -), ADediting_1559189(56386741, -), ADediting_1559190(56386766, -), ADediting_1559191(56386821, -), ADediting_1559192(56388709, -), ADediting_1559193(56388770, -), ADediting_1559194(56388797, -), ADediting_1559195(56388881, -), |
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RNA editing positional annotations for ZNF582 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| ADediting_1559184 | chr19_56384074_- | nonsynonymous SNV | ENST00000586929.5 | c.A1343G | p.K448R | 0.036 | 0.006 | -1.14 |
| ADediting_1559184 | chr19_56384074_- | nonsynonymous SNV | ENST00000619584.4 | c.A1343G | p.K448R | 0.036 | 0.006 | -1.14 |
| ADediting_1559184 | chr19_56384074_- | nonsynonymous SNV | ENST00000301310.8 | c.A1343G | p.K448R | 0.036 | 0.006 | -1.14 |
| ADediting_1559185 | chr19_56384238_- | synonymous SNV | ENST00000586929.5 | c.A1179G | p.K393K | . | . | . |
| ADediting_1559185 | chr19_56384238_- | synonymous SNV | ENST00000619584.4 | c.A1179G | p.K393K | . | . | . |
| ADediting_1559185 | chr19_56384238_- | synonymous SNV | ENST00000301310.8 | c.A1179G | p.K393K | . | . | . |
| ADediting_783532 | chr19_56383994_- | nonsynonymous SNV | ENST00000619584.4 | c.A1423G | p.R475G | 1.0 | 0.0 | 4.15 |
| ADediting_783532 | chr19_56383994_- | nonsynonymous SNV | ENST00000586929.5 | c.A1423G | p.R475G | 1.0 | 0.0 | 4.15 |
| ADediting_783532 | chr19_56383994_- | nonsynonymous SNV | ENST00000301310.8 | c.A1423G | p.R475G | 1.0 | 0.0 | 4.15 |
| ADediting_783533 | chr19_56384056_- | nonsynonymous SNV | ENST00000586929.5 | c.A1361G | p.K454R | 0.079 | 0.036 | -1.1 |
| ADediting_783533 | chr19_56384056_- | nonsynonymous SNV | ENST00000619584.4 | c.A1361G | p.K454R | 0.079 | 0.036 | -1.1 |
| ADediting_783533 | chr19_56384056_- | nonsynonymous SNV | ENST00000301310.8 | c.A1361G | p.K454R | 0.079 | 0.036 | -1.1 |
| ADediting_783534 | chr19_56384059_- | nonsynonymous SNV | ENST00000586929.5 | c.A1358G | p.Y453C | 1.0 | 0.0 | 7.26 |
| ADediting_783534 | chr19_56384059_- | nonsynonymous SNV | ENST00000301310.8 | c.A1358G | p.Y453C | 1.0 | 0.0 | 7.26 |
| ADediting_783534 | chr19_56384059_- | nonsynonymous SNV | ENST00000619584.4 | c.A1358G | p.Y453C | 1.0 | 0.0 | 7.26 |
| ADediting_783535 | chr19_56384071_- | nonsynonymous SNV | ENST00000301310.8 | c.A1346G | p.K449R | 0.107 | 0.047 | -1.72 |
| ADediting_783535 | chr19_56384071_- | nonsynonymous SNV | ENST00000619584.4 | c.A1346G | p.K449R | 0.107 | 0.047 | -1.72 |
| ADediting_783535 | chr19_56384071_- | nonsynonymous SNV | ENST00000586929.5 | c.A1346G | p.K449R | 0.107 | 0.047 | -1.72 |
| ADediting_783536 | chr19_56384072_- | nonsynonymous SNV | ENST00000301310.8 | c.A1345G | p.K449E | 0.008 | 0.157 | -2.92 |
| ADediting_783536 | chr19_56384072_- | nonsynonymous SNV | ENST00000619584.4 | c.A1345G | p.K449E | 0.008 | 0.157 | -2.92 |
| ADediting_783536 | chr19_56384072_- | nonsynonymous SNV | ENST00000586929.5 | c.A1345G | p.K449E | 0.008 | 0.157 | -2.92 |
| ADediting_783538 | chr19_56384322_- | synonymous SNV | ENST00000586929.5 | c.A1095G | p.K365K | . | . | . |
| ADediting_783538 | chr19_56384322_- | synonymous SNV | ENST00000301310.8 | c.A1095G | p.K365K | . | . | . |
| ADediting_783538 | chr19_56384322_- | synonymous SNV | ENST00000619584.4 | c.A1095G | p.K365K | . | . | . |
| ADediting_783539 | chr19_56384323_- | nonsynonymous SNV | ENST00000301310.8 | c.A1094G | p.K365R | 0.131 | 0.338 | -2.33 |
| ADediting_783539 | chr19_56384323_- | nonsynonymous SNV | ENST00000619584.4 | c.A1094G | p.K365R | 0.131 | 0.338 | -2.33 |
| ADediting_783539 | chr19_56384323_- | nonsynonymous SNV | ENST00000586929.5 | c.A1094G | p.K365R | 0.131 | 0.338 | -2.33 |
| ADediting_783540 | chr19_56384344_- | nonsynonymous SNV | ENST00000301310.8 | c.A1073G | p.Q358R | 0.055 | 0.935 | -3.05 |
| ADediting_783540 | chr19_56384344_- | nonsynonymous SNV | ENST00000619584.4 | c.A1073G | p.Q358R | 0.055 | 0.935 | -3.05 |
| ADediting_783540 | chr19_56384344_- | nonsynonymous SNV | ENST00000586929.5 | c.A1073G | p.Q358R | 0.055 | 0.935 | -3.05 |
| ADediting_783541 | chr19_56384354_- | nonsynonymous SNV | ENST00000301310.8 | c.A1063G | p.I355V | 0.34 | 0.006 | 0.12 |
| ADediting_783541 | chr19_56384354_- | nonsynonymous SNV | ENST00000586929.5 | c.A1063G | p.I355V | 0.34 | 0.006 | 0.12 |
| ADediting_783541 | chr19_56384354_- | nonsynonymous SNV | ENST00000619584.4 | c.A1063G | p.I355V | 0.34 | 0.006 | 0.12 |
| ADediting_783542 | chr19_56384360_- | nonsynonymous SNV | ENST00000301310.8 | c.A1057G | p.T353A | 0.964 | 0.523 | -0.14 |
| ADediting_783542 | chr19_56384360_- | nonsynonymous SNV | ENST00000619584.4 | c.A1057G | p.T353A | 0.964 | 0.523 | -0.14 |
| ADediting_783542 | chr19_56384360_- | nonsynonymous SNV | ENST00000586929.5 | c.A1057G | p.T353A | 0.964 | 0.523 | -0.14 |
| ADediting_783543 | chr19_56384834_- | nonsynonymous SNV | ENST00000301310.8 | c.A583G | p.N195D | 0.003 | 0.004 | -1.33 |
| ADediting_783543 | chr19_56384834_- | nonsynonymous SNV | ENST00000619584.4 | c.A583G | p.N195D | 0.003 | 0.004 | -1.33 |
| ADediting_783543 | chr19_56384834_- | nonsynonymous SNV | ENST00000586929.5 | c.A583G | p.N195D | 0.003 | 0.004 | -1.33 |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_783524 | chr19_56379994_- | intronic |
| ADediting_783525 | chr19_56380075_- | intronic |
| ADediting_783526 | chr19_56380079_- | intronic |
| ADediting_783527 | chr19_56380092_- | intronic |
| ADediting_783528 | chr19_56380102_- | intronic |
| ADediting_783529 | chr19_56380112_- | intronic |
| ADediting_783532 | chr19_56383994_- | exonic |
| ADediting_783533 | chr19_56384056_- | exonic |
| ADediting_783534 | chr19_56384059_- | exonic |
| ADediting_783535 | chr19_56384071_- | exonic |
| ADediting_783536 | chr19_56384072_- | exonic |
| ADediting_783538 | chr19_56384322_- | exonic |
| ADediting_783539 | chr19_56384323_- | exonic |
| ADediting_783540 | chr19_56384344_- | exonic |
| ADediting_783541 | chr19_56384354_- | exonic |
| ADediting_783542 | chr19_56384360_- | exonic |
| ADediting_783543 | chr19_56384834_- | exonic |
| ADediting_783550 | chr19_56388773_- | intronic |
| ADediting_783551 | chr19_56388892_- | intronic |
| ADediting_1559184 | chr19_56384074_- | exonic |
| ADediting_1559185 | chr19_56384238_- | exonic |
| ADediting_1559186 | chr19_56385482_- | intronic |
| ADediting_1559187 | chr19_56385554_- | intronic |
| ADediting_1559188 | chr19_56385617_- | intronic |
| ADediting_1559189 | chr19_56386741_- | intronic |
| ADediting_1559190 | chr19_56386766_- | intronic |
| ADediting_1559191 | chr19_56386821_- | intronic |
| ADediting_1559192 | chr19_56388709_- | intronic |
| ADediting_1559193 | chr19_56388770_- | intronic |
| ADediting_1559194 | chr19_56388797_- | intronic |
| ADediting_1559195 | chr19_56388881_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_783524 | chr19_56379994_- | SINE | Alu | Name=AluY |
| ADediting_783525 | chr19_56380075_- | SINE | Alu | Name=AluY |
| ADediting_783526 | chr19_56380079_- | SINE | Alu | Name=AluY |
| ADediting_783527 | chr19_56380092_- | SINE | Alu | Name=AluY |
| ADediting_783528 | chr19_56380102_- | SINE | Alu | Name=AluY |
| ADediting_783529 | chr19_56380112_- | SINE | Alu | Name=AluY |
| ADediting_783550 | chr19_56388773_- | SINE | Alu | Name=AluSz |
| ADediting_783551 | chr19_56388892_- | SINE | Alu | Name=AluSz |
| ADediting_1559186 | chr19_56385482_- | SINE | Alu | Name=AluJr |
| ADediting_1559187 | chr19_56385554_- | SINE | Alu | Name=AluJr |
| ADediting_1559188 | chr19_56385617_- | SINE | Alu | Name=AluJr |
| ADediting_1559189 | chr19_56386741_- | SINE | Alu | Name=AluJo |
| ADediting_1559190 | chr19_56386766_- | SINE | Alu | Name=AluJo |
| ADediting_1559191 | chr19_56386821_- | SINE | Alu | Name=AluJo |
| ADediting_1559192 | chr19_56388709_- | SINE | Alu | Name=AluSz |
| ADediting_1559193 | chr19_56388770_- | SINE | Alu | Name=AluSz |
| ADediting_1559194 | chr19_56388797_- | SINE | Alu | Name=AluSz |
| ADediting_1559195 | chr19_56388881_- | SINE | Alu | Name=AluSz |
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RNA A-to-I editing events in the alternative splicing sites for ZNF582 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZNF582 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |