|
||||||
|
 | |
| |
| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
| |
| |
| The effects of the RNA editing to the stability of the RNA structures |
| |
| |
| |
|
Gene summary for ZNF582 |
 Gene summary |
| Gene information | Gene symbol | ZNF582 | Gene ID | 147948 |
| Gene name | zinc finger protein 582 | |
| Synonyms | - | |
| Cytomap | 19q13.43 | |
| Type of gene | protein-coding | |
| Description | zinc finger protein 582 | |
| Modification date | 20200313 | |
| UniProtAcc | Q96NG8, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for ZNF582 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_783524(56379994, -), ADediting_783525(56380075, -), ADediting_783526(56380079, -), ADediting_783527(56380092, -), ADediting_783528(56380102, -), ADediting_783529(56380112, -), ADediting_783532(56383994, -), ADediting_783533(56384056, -), ADediting_783534(56384059, -), ADediting_783535(56384071, -), ADediting_783536(56384072, -), ADediting_783538(56384322, -), ADediting_783539(56384323, -), ADediting_783540(56384344, -), ADediting_783541(56384354, -), ADediting_783542(56384360, -), ADediting_783543(56384834, -), ADediting_783550(56388773, -), ADediting_783551(56388892, -), ADediting_1559184(56384074, -), ADediting_1559185(56384238, -), ADediting_1559186(56385482, -), ADediting_1559187(56385554, -), ADediting_1559188(56385617, -), ADediting_1559189(56386741, -), ADediting_1559190(56386766, -), ADediting_1559191(56386821, -), ADediting_1559192(56388709, -), ADediting_1559193(56388770, -), ADediting_1559194(56388797, -), ADediting_1559195(56388881, -), |
Top |
RNA editing positional annotations for ZNF582 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| ADediting_1559184 | chr19_56384074_- | nonsynonymous SNV | ENST00000301310.8 | c.A1343G | p.K448R | 0.036 | 0.006 | -1.14 |
| ADediting_1559184 | chr19_56384074_- | nonsynonymous SNV | ENST00000619584.4 | c.A1343G | p.K448R | 0.036 | 0.006 | -1.14 |
| ADediting_1559184 | chr19_56384074_- | nonsynonymous SNV | ENST00000586929.5 | c.A1343G | p.K448R | 0.036 | 0.006 | -1.14 |
| ADediting_1559185 | chr19_56384238_- | synonymous SNV | ENST00000301310.8 | c.A1179G | p.K393K | . | . | . |
| ADediting_1559185 | chr19_56384238_- | synonymous SNV | ENST00000619584.4 | c.A1179G | p.K393K | . | . | . |
| ADediting_1559185 | chr19_56384238_- | synonymous SNV | ENST00000586929.5 | c.A1179G | p.K393K | . | . | . |
| ADediting_783532 | chr19_56383994_- | nonsynonymous SNV | ENST00000301310.8 | c.A1423G | p.R475G | 1.0 | 0.0 | 4.15 |
| ADediting_783532 | chr19_56383994_- | nonsynonymous SNV | ENST00000619584.4 | c.A1423G | p.R475G | 1.0 | 0.0 | 4.15 |
| ADediting_783532 | chr19_56383994_- | nonsynonymous SNV | ENST00000586929.5 | c.A1423G | p.R475G | 1.0 | 0.0 | 4.15 |
| ADediting_783533 | chr19_56384056_- | nonsynonymous SNV | ENST00000301310.8 | c.A1361G | p.K454R | 0.079 | 0.036 | -1.1 |
| ADediting_783533 | chr19_56384056_- | nonsynonymous SNV | ENST00000619584.4 | c.A1361G | p.K454R | 0.079 | 0.036 | -1.1 |
| ADediting_783533 | chr19_56384056_- | nonsynonymous SNV | ENST00000586929.5 | c.A1361G | p.K454R | 0.079 | 0.036 | -1.1 |
| ADediting_783534 | chr19_56384059_- | nonsynonymous SNV | ENST00000301310.8 | c.A1358G | p.Y453C | 1.0 | 0.0 | 7.26 |
| ADediting_783534 | chr19_56384059_- | nonsynonymous SNV | ENST00000619584.4 | c.A1358G | p.Y453C | 1.0 | 0.0 | 7.26 |
| ADediting_783534 | chr19_56384059_- | nonsynonymous SNV | ENST00000586929.5 | c.A1358G | p.Y453C | 1.0 | 0.0 | 7.26 |
| ADediting_783535 | chr19_56384071_- | nonsynonymous SNV | ENST00000301310.8 | c.A1346G | p.K449R | 0.107 | 0.047 | -1.72 |
| ADediting_783535 | chr19_56384071_- | nonsynonymous SNV | ENST00000619584.4 | c.A1346G | p.K449R | 0.107 | 0.047 | -1.72 |
| ADediting_783535 | chr19_56384071_- | nonsynonymous SNV | ENST00000586929.5 | c.A1346G | p.K449R | 0.107 | 0.047 | -1.72 |
| ADediting_783536 | chr19_56384072_- | nonsynonymous SNV | ENST00000301310.8 | c.A1345G | p.K449E | 0.008 | 0.157 | -2.92 |
| ADediting_783536 | chr19_56384072_- | nonsynonymous SNV | ENST00000619584.4 | c.A1345G | p.K449E | 0.008 | 0.157 | -2.92 |
| ADediting_783536 | chr19_56384072_- | nonsynonymous SNV | ENST00000586929.5 | c.A1345G | p.K449E | 0.008 | 0.157 | -2.92 |
| ADediting_783538 | chr19_56384322_- | synonymous SNV | ENST00000301310.8 | c.A1095G | p.K365K | . | . | . |
| ADediting_783538 | chr19_56384322_- | synonymous SNV | ENST00000619584.4 | c.A1095G | p.K365K | . | . | . |
| ADediting_783538 | chr19_56384322_- | synonymous SNV | ENST00000586929.5 | c.A1095G | p.K365K | . | . | . |
| ADediting_783539 | chr19_56384323_- | nonsynonymous SNV | ENST00000301310.8 | c.A1094G | p.K365R | 0.131 | 0.338 | -2.33 |
| ADediting_783539 | chr19_56384323_- | nonsynonymous SNV | ENST00000619584.4 | c.A1094G | p.K365R | 0.131 | 0.338 | -2.33 |
| ADediting_783539 | chr19_56384323_- | nonsynonymous SNV | ENST00000586929.5 | c.A1094G | p.K365R | 0.131 | 0.338 | -2.33 |
| ADediting_783540 | chr19_56384344_- | nonsynonymous SNV | ENST00000301310.8 | c.A1073G | p.Q358R | 0.055 | 0.935 | -3.05 |
| ADediting_783540 | chr19_56384344_- | nonsynonymous SNV | ENST00000619584.4 | c.A1073G | p.Q358R | 0.055 | 0.935 | -3.05 |
| ADediting_783540 | chr19_56384344_- | nonsynonymous SNV | ENST00000586929.5 | c.A1073G | p.Q358R | 0.055 | 0.935 | -3.05 |
| ADediting_783541 | chr19_56384354_- | nonsynonymous SNV | ENST00000301310.8 | c.A1063G | p.I355V | 0.34 | 0.006 | 0.12 |
| ADediting_783541 | chr19_56384354_- | nonsynonymous SNV | ENST00000619584.4 | c.A1063G | p.I355V | 0.34 | 0.006 | 0.12 |
| ADediting_783541 | chr19_56384354_- | nonsynonymous SNV | ENST00000586929.5 | c.A1063G | p.I355V | 0.34 | 0.006 | 0.12 |
| ADediting_783542 | chr19_56384360_- | nonsynonymous SNV | ENST00000301310.8 | c.A1057G | p.T353A | 0.964 | 0.523 | -0.14 |
| ADediting_783542 | chr19_56384360_- | nonsynonymous SNV | ENST00000619584.4 | c.A1057G | p.T353A | 0.964 | 0.523 | -0.14 |
| ADediting_783542 | chr19_56384360_- | nonsynonymous SNV | ENST00000586929.5 | c.A1057G | p.T353A | 0.964 | 0.523 | -0.14 |
| ADediting_783543 | chr19_56384834_- | nonsynonymous SNV | ENST00000301310.8 | c.A583G | p.N195D | 0.003 | 0.004 | -1.33 |
| ADediting_783543 | chr19_56384834_- | nonsynonymous SNV | ENST00000619584.4 | c.A583G | p.N195D | 0.003 | 0.004 | -1.33 |
| ADediting_783543 | chr19_56384834_- | nonsynonymous SNV | ENST00000586929.5 | c.A583G | p.N195D | 0.003 | 0.004 | -1.33 |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_783524 | chr19_56379994_- | intronic |
| ADediting_783525 | chr19_56380075_- | intronic |
| ADediting_783526 | chr19_56380079_- | intronic |
| ADediting_783527 | chr19_56380092_- | intronic |
| ADediting_783528 | chr19_56380102_- | intronic |
| ADediting_783529 | chr19_56380112_- | intronic |
| ADediting_783532 | chr19_56383994_- | exonic |
| ADediting_783533 | chr19_56384056_- | exonic |
| ADediting_783534 | chr19_56384059_- | exonic |
| ADediting_783535 | chr19_56384071_- | exonic |
| ADediting_783536 | chr19_56384072_- | exonic |
| ADediting_783538 | chr19_56384322_- | exonic |
| ADediting_783539 | chr19_56384323_- | exonic |
| ADediting_783540 | chr19_56384344_- | exonic |
| ADediting_783541 | chr19_56384354_- | exonic |
| ADediting_783542 | chr19_56384360_- | exonic |
| ADediting_783543 | chr19_56384834_- | exonic |
| ADediting_783550 | chr19_56388773_- | intronic |
| ADediting_783551 | chr19_56388892_- | intronic |
| ADediting_1559184 | chr19_56384074_- | exonic |
| ADediting_1559185 | chr19_56384238_- | exonic |
| ADediting_1559186 | chr19_56385482_- | intronic |
| ADediting_1559187 | chr19_56385554_- | intronic |
| ADediting_1559188 | chr19_56385617_- | intronic |
| ADediting_1559189 | chr19_56386741_- | intronic |
| ADediting_1559190 | chr19_56386766_- | intronic |
| ADediting_1559191 | chr19_56386821_- | intronic |
| ADediting_1559192 | chr19_56388709_- | intronic |
| ADediting_1559193 | chr19_56388770_- | intronic |
| ADediting_1559194 | chr19_56388797_- | intronic |
| ADediting_1559195 | chr19_56388881_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_783524 | chr19_56379994_- | SINE | Alu | Name=AluY |
| ADediting_783525 | chr19_56380075_- | SINE | Alu | Name=AluY |
| ADediting_783526 | chr19_56380079_- | SINE | Alu | Name=AluY |
| ADediting_783527 | chr19_56380092_- | SINE | Alu | Name=AluY |
| ADediting_783528 | chr19_56380102_- | SINE | Alu | Name=AluY |
| ADediting_783529 | chr19_56380112_- | SINE | Alu | Name=AluY |
| ADediting_783550 | chr19_56388773_- | SINE | Alu | Name=AluSz |
| ADediting_783551 | chr19_56388892_- | SINE | Alu | Name=AluSz |
| ADediting_1559186 | chr19_56385482_- | SINE | Alu | Name=AluJr |
| ADediting_1559187 | chr19_56385554_- | SINE | Alu | Name=AluJr |
| ADediting_1559188 | chr19_56385617_- | SINE | Alu | Name=AluJr |
| ADediting_1559189 | chr19_56386741_- | SINE | Alu | Name=AluJo |
| ADediting_1559190 | chr19_56386766_- | SINE | Alu | Name=AluJo |
| ADediting_1559191 | chr19_56386821_- | SINE | Alu | Name=AluJo |
| ADediting_1559192 | chr19_56388709_- | SINE | Alu | Name=AluSz |
| ADediting_1559193 | chr19_56388770_- | SINE | Alu | Name=AluSz |
| ADediting_1559194 | chr19_56388797_- | SINE | Alu | Name=AluSz |
| ADediting_1559195 | chr19_56388881_- | SINE | Alu | Name=AluSz |
Top |
RNA A-to-I editing events in the alternative splicing sites for ZNF582 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZNF582 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
 | |
 | |
 | |
 | |
| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
 |
 |
 |
 |
 |
 |
| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for ZNF582 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
 |
Top |
The effects of the RNA editing to the miRNA binding sites for ZNF582 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_98288 | chr1_32086990_+ | ENSG00000018869.16 | ENST00000301310.8 | ZNF582-201 | hsa-miR-5585-3p | chr19 | 56383351 | 56383358 | 8mer-1a | 56383351 | 56383373 | 146 | -10.94 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000018869.16 | ENST00000619584.4 | ZNF582-207 | hsa-miR-5585-3p | chr19 | 56383351 | 56383358 | 8mer-1a | 56383351 | 56383373 | 146 | -10.94 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000018869.16 | ENST00000301310.8 | ZNF582-201 | hsa-miR-5585-3p | chr19 | 56383351 | 56383358 | 8mer-1a | 56383351 | 56383373 | 146 | -10.94 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000018869.16 | ENST00000619584.4 | ZNF582-207 | hsa-miR-5585-3p | chr19 | 56383351 | 56383358 | 8mer-1a | 56383351 | 56383373 | 146 | -10.94 |
| Differentially expressed gene-miRNA network |
Top |
The effects of the RNA editing to the stability of the RNA structures for ZNF582 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000301310.8 | protein_coding |  |  |
| ENST00000619584.4 | protein_coding |  |  |
| ENST00000586929.5 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_783532 | ENST00000301310.8 | chr19_56383994_- | 1582 | -770.20 | -768.40 | -787.20 |
| ADediting_783533 | ENST00000301310.8 | chr19_56384056_- | 1520 | -772.20 | -768.40 | -787.20 |
| ADediting_783534 | ENST00000301310.8 | chr19_56384059_- | 1517 | -768.50 | -768.40 | -787.20 |
| ADediting_783535 | ENST00000301310.8 | chr19_56384071_- | 1505 | -768.40 | -768.40 | -787.20 |
| ADediting_783536 | ENST00000301310.8 | chr19_56384072_- | 1504 | -768.40 | -768.40 | -787.20 |
| ADediting_1559184 | ENST00000301310.8 | chr19_56384074_- | 1502 | -768.40 | -768.40 | -787.20 |
| ADediting_1559185 | ENST00000301310.8 | chr19_56384238_- | 1338 | -772.80 | -768.40 | -787.20 |
| ADediting_783538 | ENST00000301310.8 | chr19_56384322_- | 1254 | -768.80 | -768.40 | -787.20 |
| ADediting_783539 | ENST00000301310.8 | chr19_56384323_- | 1253 | -768.40 | -768.40 | -787.20 |
| ADediting_783540 | ENST00000301310.8 | chr19_56384344_- | 1232 | -769.40 | -768.40 | -787.20 |
| ADediting_783541 | ENST00000301310.8 | chr19_56384354_- | 1222 | -768.50 | -768.40 | -787.20 |
| ADediting_783542 | ENST00000301310.8 | chr19_56384360_- | 1216 | -769.90 | -768.40 | -787.20 |
| ADediting_783543 | ENST00000301310.8 | chr19_56384834_- | 742 | -773.80 | -768.40 | -787.20 |
| ADediting_783532 | ENST00000619584.4 | chr19_56383994_- | 1582 | -613.60 | -611.80 | -631.10 |
| ADediting_783533 | ENST00000619584.4 | chr19_56384056_- | 1520 | -615.60 | -611.80 | -631.10 |
| ADediting_783534 | ENST00000619584.4 | chr19_56384059_- | 1517 | -611.90 | -611.80 | -631.10 |
| ADediting_783535 | ENST00000619584.4 | chr19_56384071_- | 1505 | -611.80 | -611.80 | -631.10 |
| ADediting_783536 | ENST00000619584.4 | chr19_56384072_- | 1504 | -611.80 | -611.80 | -631.10 |
| ADediting_1559184 | ENST00000619584.4 | chr19_56384074_- | 1502 | -611.80 | -611.80 | -631.10 |
| ADediting_1559185 | ENST00000619584.4 | chr19_56384238_- | 1338 | -616.20 | -611.80 | -631.10 |
| ADediting_783538 | ENST00000619584.4 | chr19_56384322_- | 1254 | -612.20 | -611.80 | -631.10 |
| ADediting_783539 | ENST00000619584.4 | chr19_56384323_- | 1253 | -611.80 | -611.80 | -631.10 |
| ADediting_783540 | ENST00000619584.4 | chr19_56384344_- | 1232 | -612.80 | -611.80 | -631.10 |
| ADediting_783541 | ENST00000619584.4 | chr19_56384354_- | 1222 | -611.90 | -611.80 | -631.10 |
| ADediting_783542 | ENST00000619584.4 | chr19_56384360_- | 1216 | -613.30 | -611.80 | -631.10 |
| ADediting_783543 | ENST00000619584.4 | chr19_56384834_- | 742 | -617.70 | -611.80 | -631.10 |
| ADediting_783532 | ENST00000586929.5 | chr19_56383994_- | 1829 | -635.40 | -633.60 | -651.40 |
| ADediting_783533 | ENST00000586929.5 | chr19_56384056_- | 1767 | -637.40 | -633.60 | -651.40 |
| ADediting_783534 | ENST00000586929.5 | chr19_56384059_- | 1764 | -633.70 | -633.60 | -651.40 |
| ADediting_783535 | ENST00000586929.5 | chr19_56384071_- | 1752 | -633.60 | -633.60 | -651.40 |
| ADediting_783536 | ENST00000586929.5 | chr19_56384072_- | 1751 | -633.60 | -633.60 | -651.40 |
| ADediting_1559184 | ENST00000586929.5 | chr19_56384074_- | 1749 | -633.60 | -633.60 | -651.40 |
| ADediting_1559185 | ENST00000586929.5 | chr19_56384238_- | 1585 | -638.00 | -633.60 | -651.40 |
| ADediting_783538 | ENST00000586929.5 | chr19_56384322_- | 1501 | -634.00 | -633.60 | -651.40 |
| ADediting_783539 | ENST00000586929.5 | chr19_56384323_- | 1500 | -633.60 | -633.60 | -651.40 |
| ADediting_783540 | ENST00000586929.5 | chr19_56384344_- | 1479 | -634.60 | -633.60 | -651.40 |
| ADediting_783541 | ENST00000586929.5 | chr19_56384354_- | 1469 | -633.70 | -633.60 | -651.40 |
| ADediting_783542 | ENST00000586929.5 | chr19_56384360_- | 1463 | -635.10 | -633.60 | -651.40 |
| ADediting_783543 | ENST00000586929.5 | chr19_56384834_- | 989 | -638.00 | -633.60 | -651.40 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
Top |
Relation with ADAR for ZNF582 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_1559186 | chr19_56385482_- | 0.00149705408021173 | 0.257038404429882 | 2.3413984849216e-06 | 0.374515159908673 | 0.4999188909389 | -0.0555041124038628 |
| CER | ADediting_1559188 | chr19_56385617_- | 0.00403109942169482 | 0.233499973915024 | 1.5602228041325e-05 | 0.344736909202629 | 0.397159593819587 | 0.0696317088880695 |
| CER | ADediting_783532 | chr19_56383994_- | 1.81951030745807e-05 | 0.342186238371386 | 0.00389179734985849 | 0.234374786338982 | 0.724262358331996 | -0.0290402469822657 |
| TCX | ADediting_783532 | chr19_56383994_- | 1.50283942812647e-05 | 0.345355253399335 | 0.0106668729297659 | 0.207941837737467 | 0.239185582248839 | 0.0966871673688111 |
| CER | ADediting_783534 | chr19_56384059_- | 3.16575278254077e-06 | 0.369973967050088 | 6.70304527882279e-08 | 0.423446591786217 | 0.611736047632038 | -0.0417764938790772 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 3.80527100018086e-29 | 0.579015383126178 | 9.77758266770616e-34 | 0.61571677763134 | 9.87870733490116e-08 | 0.297006445777193 |
| AC | 4.14646333217203e-52 | 0.778627608612909 | 7.38266279137462e-39 | 0.704854065039932 | 5.93991503560485e-15 | 0.467102186076496 |
| PCC | 2.90904963544964e-15 | 0.530587736018812 | 8.23939531827897e-18 | 0.569457635730267 | 0.0140652250306173 | 0.177433076877704 |
| CER | 3.22190075595077e-16 | 0.602972317037114 | 4.13302221437344e-20 | 0.659921197214994 | 0.00522503960404376 | 0.226948228375934 |
| TCX | 8.64771540947598e-11 | 0.498311270992706 | 0.00190629756781093 | 0.251494644556952 | 5.12943403600688e-07 | 0.396390074838171 |
| FP | 8.8314862583536e-17 | 0.57085852687311 | 5.06553830738576e-29 | 0.713741565557855 | 0.000225586530909129 | 0.273113571230369 |
| IFG | 0.000621884385029192 | 0.636673283960663 | 4.90099949169347e-05 | 0.720302945702174 | 0.332996146421975 | 0.201953688788875 |
| PG | 2.28578654927905e-40 | 0.786510049001607 | 6.19295357906325e-23 | 0.641291797857616 | 0.302816950279433 | 0.0759562639342789 |
| STG | 3.68160724510723e-15 | 0.729211278907697 | 1.77489675970066e-14 | 0.716681362295983 | 0.133793320183873 | 0.164936848682137 |
Top |
Relation with AD stages for ZNF582 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 9.98573100864886e-05 | 0.365611818805345 |
| TCX | 1.01185036295549e-05 | 0.414269409951287 |
Top |
RelatedDrugs for ZNF582 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for ZNF582 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|