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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for MGAT5B |
 Gene summary |
| Gene information | Gene symbol | MGAT5B | Gene ID | 146664 |
| Gene name | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B | |
| Synonyms | GnT-IX|GnT-VB | |
| Cytomap | 17q25.2 | |
| Type of gene | protein-coding | |
| Description | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase BN-acetylglucosaminyl-transferase VbN-acetylglucosaminyltransferase IXalpha-mannoside beta-1,6-N-acetylglucosaminyltransferase Bbeta(1,6)-N-acetylglucosaminyltransferase VglcNAc-T | |
| Modification date | 20200313 | |
| UniProtAcc | Q3V5L5, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| MGAT5B | GO:0018242 | protein O-linked glycosylation via serine | 19846580 |
Top |
RNA A-to-I events for MGAT5B |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_667873(76892502, +), ADediting_667874(76894601, +), ADediting_667875(76894644, +), ADediting_667876(76894668, +), ADediting_667877(76894684, +), ADediting_667878(76894690, +), ADediting_667879(76894693, +), ADediting_667880(76894703, +), ADediting_667881(76894708, +), ADediting_667882(76894734, +), ADediting_667895(76913929, +), ADediting_667896(76913955, +), ADediting_667897(76913986, +), ADediting_667898(76913990, +), ADediting_667899(76913994, +), ADediting_667900(76914007, +), ADediting_667901(76914040, +), ADediting_667902(76914084, +), ADediting_667903(76914738, +), ADediting_667904(76914818, +), ADediting_667905(76914885, +), ADediting_667907(76916534, +), ADediting_667908(76916570, +), ADediting_667914(76927260, +), ADediting_667915(76927273, +), ADediting_667916(76927326, +), ADediting_667917(76927339, +), ADediting_667918(76927340, +), ADediting_667919(76927357, +), ADediting_667920(76927369, +), ADediting_667921(76927379, +), ADediting_667922(76927405, +), ADediting_667923(76927412, +), ADediting_667924(76927414, +), ADediting_667925(76927423, +), ADediting_667926(76927428, +), ADediting_667927(76927429, +), ADediting_667928(76927449, +), ADediting_667929(76927483, +), ADediting_667930(76927501, +), ADediting_667931(76927502, +), ADediting_667932(76927514, +), ADediting_667933(76927522, +), ADediting_667934(76928429, +), ADediting_667935(76928443, +), ADediting_667936(76928445, +), ADediting_667937(76928451, +), ADediting_667938(76928452, +), ADediting_667939(76928521, +), ADediting_667940(76928540, +), ADediting_667941(76928585, +), ADediting_667942(76928594, +), ADediting_667943(76928598, +), ADediting_667944(76928611, +), ADediting_667945(76928620, +), ADediting_667946(76928626, +), ADediting_667947(76928685, +), ADediting_667948(76928692, +), ADediting_667949(76928945, +), ADediting_667950(76928946, +), ADediting_667951(76928995, +), ADediting_667952(76929031, +), ADediting_667953(76929046, +), ADediting_667954(76929055, +), ADediting_667955(76931191, +), ADediting_667956(76931197, +), ADediting_667957(76931214, +), ADediting_667958(76931226, +), ADediting_667959(76931271, +), ADediting_667960(76931277, +), ADediting_667961(76931280, +), ADediting_667962(76931340, +), ADediting_667963(76931359, +), ADediting_667964(76931371, +), ADediting_667965(76932233, +), ADediting_667966(76932245, +), ADediting_667967(76932250, +), ADediting_667968(76932272, +), ADediting_667969(76932305, +), ADediting_667970(76932408, +), ADediting_667971(76936152, +), ADediting_667972(76936224, +), ADediting_667973(76936230, +), ADediting_667974(76936314, +), ADediting_667975(76938702, +), ADediting_667977(76941605, +), ADediting_667978(76941606, +), ADediting_667979(76942266, +), ADediting_667980(76942272, +), ADediting_667981(76942296, +), ADediting_667982(76943680, +), ADediting_667983(76945523, +), ADediting_667984(76945563, +), ADediting_1549450(76914847, +), ADediting_1628785(76936236, +), |
Top |
RNA editing positional annotations for MGAT5B using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_667873 | chr17_76892502_+ | intronic |
| ADediting_667874 | chr17_76894601_+ | intronic |
| ADediting_667875 | chr17_76894644_+ | intronic |
| ADediting_667876 | chr17_76894668_+ | intronic |
| ADediting_667877 | chr17_76894684_+ | intronic |
| ADediting_667878 | chr17_76894690_+ | intronic |
| ADediting_667879 | chr17_76894693_+ | intronic |
| ADediting_667880 | chr17_76894703_+ | intronic |
| ADediting_667881 | chr17_76894708_+ | intronic |
| ADediting_667882 | chr17_76894734_+ | intronic |
| ADediting_667895 | chr17_76913929_+ | intronic |
| ADediting_667896 | chr17_76913955_+ | intronic |
| ADediting_667897 | chr17_76913986_+ | intronic |
| ADediting_667898 | chr17_76913990_+ | intronic |
| ADediting_667899 | chr17_76913994_+ | intronic |
| ADediting_667900 | chr17_76914007_+ | intronic |
| ADediting_667901 | chr17_76914040_+ | intronic |
| ADediting_667902 | chr17_76914084_+ | intronic |
| ADediting_667903 | chr17_76914738_+ | intronic |
| ADediting_667904 | chr17_76914818_+ | intronic |
| ADediting_667905 | chr17_76914885_+ | intronic |
| ADediting_667907 | chr17_76916534_+ | intronic |
| ADediting_667908 | chr17_76916570_+ | intronic |
| ADediting_667914 | chr17_76927260_+ | intronic |
| ADediting_667915 | chr17_76927273_+ | intronic |
| ADediting_667916 | chr17_76927326_+ | intronic |
| ADediting_667917 | chr17_76927339_+ | intronic |
| ADediting_667918 | chr17_76927340_+ | intronic |
| ADediting_667919 | chr17_76927357_+ | intronic |
| ADediting_667920 | chr17_76927369_+ | intronic |
| ADediting_667921 | chr17_76927379_+ | intronic |
| ADediting_667922 | chr17_76927405_+ | intronic |
| ADediting_667923 | chr17_76927412_+ | intronic |
| ADediting_667924 | chr17_76927414_+ | intronic |
| ADediting_667925 | chr17_76927423_+ | intronic |
| ADediting_667926 | chr17_76927428_+ | intronic |
| ADediting_667927 | chr17_76927429_+ | intronic |
| ADediting_667928 | chr17_76927449_+ | intronic |
| ADediting_667929 | chr17_76927483_+ | intronic |
| ADediting_667930 | chr17_76927501_+ | intronic |
| ADediting_667931 | chr17_76927502_+ | intronic |
| ADediting_667932 | chr17_76927514_+ | intronic |
| ADediting_667933 | chr17_76927522_+ | intronic |
| ADediting_667934 | chr17_76928429_+ | intronic |
| ADediting_667935 | chr17_76928443_+ | intronic |
| ADediting_667936 | chr17_76928445_+ | intronic |
| ADediting_667937 | chr17_76928451_+ | intronic |
| ADediting_667938 | chr17_76928452_+ | intronic |
| ADediting_667939 | chr17_76928521_+ | intronic |
| ADediting_667940 | chr17_76928540_+ | intronic |
| ADediting_667941 | chr17_76928585_+ | intronic |
| ADediting_667942 | chr17_76928594_+ | intronic |
| ADediting_667943 | chr17_76928598_+ | intronic |
| ADediting_667944 | chr17_76928611_+ | intronic |
| ADediting_667945 | chr17_76928620_+ | intronic |
| ADediting_667946 | chr17_76928626_+ | intronic |
| ADediting_667947 | chr17_76928685_+ | intronic |
| ADediting_667948 | chr17_76928692_+ | intronic |
| ADediting_667949 | chr17_76928945_+ | intronic |
| ADediting_667950 | chr17_76928946_+ | intronic |
| ADediting_667951 | chr17_76928995_+ | intronic |
| ADediting_667952 | chr17_76929031_+ | intronic |
| ADediting_667953 | chr17_76929046_+ | intronic |
| ADediting_667954 | chr17_76929055_+ | intronic |
| ADediting_667955 | chr17_76931191_+ | intronic |
| ADediting_667956 | chr17_76931197_+ | intronic |
| ADediting_667957 | chr17_76931214_+ | intronic |
| ADediting_667958 | chr17_76931226_+ | intronic |
| ADediting_667959 | chr17_76931271_+ | intronic |
| ADediting_667960 | chr17_76931277_+ | intronic |
| ADediting_667961 | chr17_76931280_+ | intronic |
| ADediting_667962 | chr17_76931340_+ | intronic |
| ADediting_667963 | chr17_76931359_+ | intronic |
| ADediting_667964 | chr17_76931371_+ | intronic |
| ADediting_667965 | chr17_76932233_+ | intronic |
| ADediting_667966 | chr17_76932245_+ | intronic |
| ADediting_667967 | chr17_76932250_+ | intronic |
| ADediting_667968 | chr17_76932272_+ | intronic |
| ADediting_667969 | chr17_76932305_+ | intronic |
| ADediting_667970 | chr17_76932408_+ | intronic |
| ADediting_667971 | chr17_76936152_+ | intronic |
| ADediting_667972 | chr17_76936224_+ | intronic |
| ADediting_667973 | chr17_76936230_+ | intronic |
| ADediting_667974 | chr17_76936314_+ | intronic |
| ADediting_667975 | chr17_76938702_+ | intronic |
| ADediting_667977 | chr17_76941605_+ | intronic |
| ADediting_667978 | chr17_76941606_+ | intronic |
| ADediting_667979 | chr17_76942266_+ | intronic |
| ADediting_667980 | chr17_76942272_+ | intronic |
| ADediting_667981 | chr17_76942296_+ | intronic |
| ADediting_667982 | chr17_76943680_+ | intronic |
| ADediting_667983 | chr17_76945523_+ | intronic |
| ADediting_667984 | chr17_76945563_+ | intronic |
| ADediting_1549450 | chr17_76914847_+ | intronic |
| ADediting_1628785 | chr17_76936236_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_667874 | chr17_76894601_+ | SINE | Alu | Name=AluSg7 |
| ADediting_667875 | chr17_76894644_+ | SINE | Alu | Name=AluSg7 |
| ADediting_667876 | chr17_76894668_+ | SINE | Alu | Name=AluSg7 |
| ADediting_667877 | chr17_76894684_+ | SINE | Alu | Name=AluSg7 |
| ADediting_667878 | chr17_76894690_+ | SINE | Alu | Name=AluSg7 |
| ADediting_667879 | chr17_76894693_+ | SINE | Alu | Name=AluSg7 |
| ADediting_667880 | chr17_76894703_+ | SINE | Alu | Name=AluSg7 |
| ADediting_667881 | chr17_76894708_+ | SINE | Alu | Name=AluSg7 |
| ADediting_667882 | chr17_76894734_+ | SINE | Alu | Name=AluSg7 |
| ADediting_667895 | chr17_76913929_+ | SINE | Alu | Name=AluJb |
| ADediting_667896 | chr17_76913955_+ | SINE | Alu | Name=AluJb |
| ADediting_667897 | chr17_76913986_+ | SINE | Alu | Name=AluJb |
| ADediting_667898 | chr17_76913990_+ | SINE | Alu | Name=AluJb |
| ADediting_667899 | chr17_76913994_+ | SINE | Alu | Name=AluJb |
| ADediting_667900 | chr17_76914007_+ | SINE | Alu | Name=AluJb |
| ADediting_667901 | chr17_76914040_+ | SINE | Alu | Name=AluJb |
| ADediting_667902 | chr17_76914084_+ | SINE | Alu | Name=AluJb |
| ADediting_667903 | chr17_76914738_+ | SINE | Alu | Name=AluSx |
| ADediting_667904 | chr17_76914818_+ | SINE | Alu | Name=AluSx |
| ADediting_667905 | chr17_76914885_+ | SINE | Alu | Name=AluSx |
| ADediting_667907 | chr17_76916534_+ | SINE | Alu | Name=AluJb |
| ADediting_667908 | chr17_76916570_+ | SINE | Alu | Name=AluJb |
| ADediting_667914 | chr17_76927260_+ | SINE | Alu | Name=AluJb |
| ADediting_667915 | chr17_76927273_+ | SINE | Alu | Name=AluJb |
| ADediting_667916 | chr17_76927326_+ | SINE | Alu | Name=AluJb |
| ADediting_667917 | chr17_76927339_+ | SINE | Alu | Name=AluJb |
| ADediting_667918 | chr17_76927340_+ | SINE | Alu | Name=AluJb |
| ADediting_667919 | chr17_76927357_+ | SINE | Alu | Name=AluJb |
| ADediting_667920 | chr17_76927369_+ | SINE | Alu | Name=AluJb |
| ADediting_667921 | chr17_76927379_+ | SINE | Alu | Name=AluJb |
| ADediting_667922 | chr17_76927405_+ | SINE | Alu | Name=AluJb |
| ADediting_667923 | chr17_76927412_+ | SINE | Alu | Name=AluJb |
| ADediting_667924 | chr17_76927414_+ | SINE | Alu | Name=AluJb |
| ADediting_667925 | chr17_76927423_+ | SINE | Alu | Name=AluJb |
| ADediting_667926 | chr17_76927428_+ | SINE | Alu | Name=AluJb |
| ADediting_667927 | chr17_76927429_+ | SINE | Alu | Name=AluJb |
| ADediting_667928 | chr17_76927449_+ | SINE | Alu | Name=AluJb |
| ADediting_667929 | chr17_76927483_+ | SINE | Alu | Name=AluJb |
| ADediting_667930 | chr17_76927501_+ | SINE | Alu | Name=AluJb |
| ADediting_667931 | chr17_76927502_+ | SINE | Alu | Name=AluJb |
| ADediting_667932 | chr17_76927514_+ | SINE | Alu | Name=AluJb |
| ADediting_667933 | chr17_76927522_+ | SINE | Alu | Name=AluJb |
| ADediting_667934 | chr17_76928429_+ | SINE | Alu | Name=AluSx1 |
| ADediting_667935 | chr17_76928443_+ | SINE | Alu | Name=AluSx1 |
| ADediting_667936 | chr17_76928445_+ | SINE | Alu | Name=AluSx1 |
| ADediting_667937 | chr17_76928451_+ | SINE | Alu | Name=AluSx1 |
| ADediting_667938 | chr17_76928452_+ | SINE | Alu | Name=AluSx1 |
| ADediting_667939 | chr17_76928521_+ | SINE | Alu | Name=AluSx1 |
| ADediting_667940 | chr17_76928540_+ | SINE | Alu | Name=AluSx1 |
| ADediting_667941 | chr17_76928585_+ | SINE | Alu | Name=AluSx1 |
| ADediting_667942 | chr17_76928594_+ | SINE | Alu | Name=AluSx1 |
| ADediting_667943 | chr17_76928598_+ | SINE | Alu | Name=AluSx1 |
| ADediting_667944 | chr17_76928611_+ | SINE | Alu | Name=AluSx1 |
| ADediting_667945 | chr17_76928620_+ | SINE | Alu | Name=AluSx1 |
| ADediting_667946 | chr17_76928626_+ | SINE | Alu | Name=AluSx1 |
| ADediting_667947 | chr17_76928685_+ | SINE | Alu | Name=AluSx1 |
| ADediting_667948 | chr17_76928692_+ | SINE | Alu | Name=AluSx1 |
| ADediting_667949 | chr17_76928945_+ | SINE | Alu | Name=AluSx |
| ADediting_667950 | chr17_76928946_+ | SINE | Alu | Name=AluSx |
| ADediting_667951 | chr17_76928995_+ | SINE | Alu | Name=AluSx |
| ADediting_667952 | chr17_76929031_+ | SINE | Alu | Name=AluSx |
| ADediting_667953 | chr17_76929046_+ | SINE | Alu | Name=AluSx |
| ADediting_667954 | chr17_76929055_+ | SINE | Alu | Name=AluSx |
| ADediting_667955 | chr17_76931191_+ | SINE | Alu | Name=AluSx |
| ADediting_667956 | chr17_76931197_+ | SINE | Alu | Name=AluSx |
| ADediting_667957 | chr17_76931214_+ | SINE | Alu | Name=AluSx |
| ADediting_667958 | chr17_76931226_+ | SINE | Alu | Name=AluSx |
| ADediting_667959 | chr17_76931271_+ | SINE | Alu | Name=AluSx |
| ADediting_667960 | chr17_76931277_+ | SINE | Alu | Name=AluSx |
| ADediting_667961 | chr17_76931280_+ | SINE | Alu | Name=AluSx |
| ADediting_667962 | chr17_76931340_+ | SINE | Alu | Name=AluSx |
| ADediting_667963 | chr17_76931359_+ | SINE | Alu | Name=AluSx |
| ADediting_667964 | chr17_76931371_+ | SINE | Alu | Name=AluSx |
| ADediting_667965 | chr17_76932233_+ | SINE | Alu | Name=AluJr |
| ADediting_667966 | chr17_76932245_+ | SINE | Alu | Name=AluJr |
| ADediting_667967 | chr17_76932250_+ | SINE | Alu | Name=AluJr |
| ADediting_667968 | chr17_76932272_+ | SINE | Alu | Name=AluJr |
| ADediting_667969 | chr17_76932305_+ | SINE | Alu | Name=AluJr |
| ADediting_667970 | chr17_76932408_+ | SINE | Alu | Name=AluJr |
| ADediting_667971 | chr17_76936152_+ | SINE | Alu | Name=AluSx3 |
| ADediting_667972 | chr17_76936224_+ | SINE | Alu | Name=AluSx3 |
| ADediting_667973 | chr17_76936230_+ | SINE | Alu | Name=AluSx3 |
| ADediting_667974 | chr17_76936314_+ | SINE | Alu | Name=AluSx3 |
| ADediting_667975 | chr17_76938702_+ | SINE | Alu | Name=AluJr |
| ADediting_667977 | chr17_76941605_+ | SINE | Alu | Name=AluSz6 |
| ADediting_667978 | chr17_76941606_+ | SINE | Alu | Name=AluSz6 |
| ADediting_667979 | chr17_76942266_+ | SINE | Alu | Name=AluSz |
| ADediting_667980 | chr17_76942272_+ | SINE | Alu | Name=AluSz |
| ADediting_667981 | chr17_76942296_+ | SINE | Alu | Name=AluSz |
| ADediting_667982 | chr17_76943680_+ | SINE | Alu | Name=FLAM_C |
| ADediting_667983 | chr17_76945523_+ | SINE | Alu | Name=AluSx1 |
| ADediting_667984 | chr17_76945563_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1549450 | chr17_76914847_+ | SINE | Alu | Name=AluSx |
| ADediting_1628785 | chr17_76936236_+ | SINE | Alu | Name=AluSx3 |
Top |
RNA A-to-I editing events in the alternative splicing sites for MGAT5B |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for MGAT5B |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for MGAT5B |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for MGAT5B |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_667895 | chr17_76913929_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-6511a-3p | chr17 | 76913928 | 76913935 | 8mer-1a | 76913913 | 76913935 | 151 | -21.01 |
| ADediting_667895 | chr17_76913929_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-6511b-3p | chr17 | 76913928 | 76913935 | 8mer-1a | 76913912 | 76913935 | 148 | -17.97 |
| ADediting_667898 | chr17_76913990_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-1207-3p | chr17 | 76913984 | 76913990 | 7mer-m8 | 76913973 | 76913991 | 145 | -15.47 |
| ADediting_667898 | chr17_76913990_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-646 | chr17 | 76913986 | 76913992 | 7mer-m8 | 76913975 | 76913993 | 145 | -17.14 |
| ADediting_667900 | chr17_76914007_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-4469 | chr17 | 76914005 | 76914011 | 7mer-m8 | 76913991 | 76914012 | 164 | -28.66 |
| ADediting_667900 | chr17_76914007_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-4667-3p | chr17 | 76914003 | 76914010 | 8mer-1a | 76913991 | 76914010 | 155 | -24.11 |
| ADediting_667900 | chr17_76914007_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-5193 | chr17 | 76914002 | 76914008 | 7mer-m8 | 76913988 | 76914009 | 140 | -19.24 |
| ADediting_667901 | chr17_76914040_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-1184 | chr17 | 76914037 | 76914043 | 7mer-m8 | 76914018 | 76914044 | 155 | -23.95 |
| ADediting_667901 | chr17_76914040_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-4418 | chr17 | 76914038 | 76914044 | 7mer-m8 | 76914029 | 76914045 | 146 | -15.66 |
| ADediting_667901 | chr17_76914040_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-509-3-5p | chr17 | 76914038 | 76914044 | 7mer-m8 | 76914024 | 76914045 | 151 | -18.33 |
| ADediting_667901 | chr17_76914040_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-509-5p | chr17 | 76914038 | 76914044 | 7mer-m8 | 76914025 | 76914045 | 142 | -18.29 |
| ADediting_667901 | chr17_76914040_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-7156-3p | chr17 | 76914036 | 76914042 | 7mer-m8 | 76914018 | 76914043 | 143 | -21.84 |
| ADediting_667902 | chr17_76914084_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-5691 | chr17 | 76914082 | 76914089 | 8mer-1a | 76914068 | 76914089 | 153 | -24.16 |
| ADediting_667902 | chr17_76914084_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-6773-3p | chr17 | 76914078 | 76914085 | 8mer-1a | 76914064 | 76914085 | 142 | -13.64 |
| ADediting_667902 | chr17_76914084_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-6805-3p | chr17 | 76914082 | 76914089 | 8mer-1a | 76914068 | 76914089 | 154 | -21.48 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_667900 | chr17_76914007_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-3667-3p | chr17 | 76914003 | 76914010 | 8mer-1a | 76913986 | 76914010 | 156 | -21.62 |
| ADediting_667900 | chr17_76914007_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-670-3p | chr17 | 76914001 | 76914007 | 7mer-m8 | 76913989 | 76914008 | 141 | -11.83 |
| ADediting_667901 | chr17_76914040_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-1183 | chr17 | 76914038 | 76914044 | 7mer-m8 | 76914019 | 76914045 | 140 | -17.1 |
| ADediting_667901 | chr17_76914040_+ | ENSG00000167889.12 | ENST00000374998.3 | MGAT5B-202 | hsa-miR-3137 | chr17 | 76914037 | 76914043 | 7mer-m8 | 76914021 | 76914044 | 153 | -24.85 |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1391023 | chr8_140732605_- | ENSG00000167889.12 | ENST00000301618.8 | MGAT5B-201 | hsa-miR-151a-3p | chr17 | 76949701 | 76949707 | 7mer-m8 | 76949683 | 76949708 | 156 | -27.62 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000167889.12 | ENST00000428789.6 | MGAT5B-203 | hsa-miR-151a-3p | chr17 | 76949701 | 76949707 | 7mer-m8 | 76949683 | 76949708 | 156 | -27.62 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000167889.12 | ENST00000569840.6 | MGAT5B-209 | hsa-miR-151a-3p | chr17 | 76949701 | 76949707 | 7mer-m8 | 76949683 | 76949708 | 156 | -27.62 |
| ADediting_496066 | chr15_66496985_- | ENSG00000167889.12 | ENST00000301618.8 | MGAT5B-201 | hsa-miR-4512 | chr17 | 76949139 | 76949145 | 7mer-m8 | 76949128 | 76949146 | 151 | -26.83 |
| ADediting_496066 | chr15_66496985_- | ENSG00000167889.12 | ENST00000428789.6 | MGAT5B-203 | hsa-miR-4512 | chr17 | 76949139 | 76949145 | 7mer-m8 | 76949128 | 76949146 | 151 | -26.83 |
| ADediting_496066 | chr15_66496985_- | ENSG00000167889.12 | ENST00000569840.6 | MGAT5B-209 | hsa-miR-4512 | chr17 | 76949139 | 76949145 | 7mer-m8 | 76949128 | 76949146 | 151 | -26.83 |
| ADediting_527135 | chr16_24203190_+ | ENSG00000167889.12 | ENST00000301618.8 | MGAT5B-201 | hsa-miR-1273h-3p | chr17 | 76949110 | 76949116 | 7mer-m8 | 76949093 | 76949117 | 157 | -23.17 |
| ADediting_527135 | chr16_24203190_+ | ENSG00000167889.12 | ENST00000428789.6 | MGAT5B-203 | hsa-miR-1273h-3p | chr17 | 76949110 | 76949116 | 7mer-m8 | 76949093 | 76949117 | 157 | -23.17 |
| ADediting_527135 | chr16_24203190_+ | ENSG00000167889.12 | ENST00000569840.6 | MGAT5B-209 | hsa-miR-1273h-3p | chr17 | 76949110 | 76949116 | 7mer-m8 | 76949093 | 76949117 | 157 | -23.17 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337758 | chr7_5495892_- | ENSG00000167889.12 | ENST00000301618.8 | MGAT5B-201 | hsa-miR-589-5p | chr17 | 76950272 | 76950279 | 8mer-1a | 76950258 | 76950279 | 145 | -15.84 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000167889.12 | ENST00000428789.6 | MGAT5B-203 | hsa-miR-589-5p | chr17 | 76950272 | 76950279 | 8mer-1a | 76950258 | 76950279 | 145 | -15.84 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000167889.12 | ENST00000569840.6 | MGAT5B-209 | hsa-miR-589-5p | chr17 | 76950272 | 76950279 | 8mer-1a | 76950258 | 76950279 | 145 | -15.84 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for MGAT5B |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000374998.3 | lncRNA |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_667895 | ENST00000374998.3 | chr17_76913929_+ | 1492 | -733.60 | -731.70 | -745.10 |
| ADediting_667896 | ENST00000374998.3 | chr17_76913955_+ | 1518 | -731.80 | -731.70 | -745.10 |
| ADediting_667897 | ENST00000374998.3 | chr17_76913986_+ | 1549 | -733.20 | -731.70 | -745.10 |
| ADediting_667898 | ENST00000374998.3 | chr17_76913990_+ | 1553 | -733.10 | -731.70 | -745.10 |
| ADediting_667899 | ENST00000374998.3 | chr17_76913994_+ | 1557 | -731.00 | -731.70 | -745.10 |
| ADediting_667900 | ENST00000374998.3 | chr17_76914007_+ | 1570 | -733.30 | -731.70 | -745.10 |
| ADediting_667901 | ENST00000374998.3 | chr17_76914040_+ | 1603 | -733.80 | -731.70 | -745.10 |
| ADediting_667902 | ENST00000374998.3 | chr17_76914084_+ | 1647 | -736.10 | -731.70 | -745.10 |
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Relation with ADAR for MGAT5B |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_667899 | chr17_76913994_+ | 0.0351792247982101 | 0.172131963484749 | 8.82524552779944e-05 | 0.314597208366629 | 0.00326886965143815 | 0.238668411016454 |
| CER | ADediting_667918 | chr17_76927340_+ | 0.00759347911088888 | 0.217183115511279 | 3.19321064517062e-06 | 0.369842934652859 | 0.0031170940927477 | 0.239825921636602 |
| CER | ADediting_667933 | chr17_76927522_+ | 0.0870934216255065 | 0.140179156015705 | 8.90622942106582e-05 | 0.314429602517747 | 3.19150403230581e-05 | 0.332668521287836 |
| DLPFC | ADediting_667981 | chr17_76942296_+ | 0.0442377735120246 | 0.114351192249178 | 0.339714752075923 | 0.0544045757758507 | 2.48494523256862e-10 | 0.349421219072011 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 4.88176249877243e-32 | 0.602682056933786 | 1.6853744356539e-51 | 0.723491654121278 | 2.99781978967384e-08 | 0.308286206441398 |
| AC | 2.12195241265324e-37 | 0.695027089048144 | 6.29083452745273e-69 | 0.843621410341842 | 0.000182180563867684 | 0.234562850811188 |
| PCC | 8.07412038976892e-39 | 0.770543233140038 | 5.26788905594146e-58 | 0.863215328579055 | 0.0060151485772799 | 0.198089468754294 |
| TCX | 4.08150162697798e-08 | 0.429696983902321 | 5.37688990922854e-20 | 0.658408998851916 | 0.000210014399409926 | -0.298225426522559 |
| FP | 4.98425263050696e-12 | 0.487796674008955 | 1.33291469313037e-05 | 0.320022767643551 | 5.5254653197629e-07 | 0.364850382405695 |
| IFG | 5.7628483611047e-05 | 0.7157132940881 | 1.37825808067292e-06 | 0.802717710016758 | 0.22342205689421 | 0.25245236841092 |
| STG | 1.15893387953213e-07 | 0.539888802019929 | 3.60454946052883e-07 | 0.521690668995552 | 0.055005967157842 | 0.210165804840105 |
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Relation with AD stages for MGAT5B |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_667934 | chr17_76928429_+ | 0.00126298234334077 | 0.306325193145214 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 9.66883752387671e-05 | 0.36629472326752 |
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RelatedDrugs for MGAT5B |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MGAT5B |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| MGAT5B | C0032460 | Polycystic Ovary Syndrome | 1 | CTD_human |
| MGAT5B | C1136382 | Sclerocystic Ovaries | 1 | CTD_human |
| MGAT5B | C3714756 | Intellectual Disability | 1 | GENOMICS_ENGLAND |
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