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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for CSF3R |
 Gene summary |
| Gene information | Gene symbol | CSF3R | Gene ID | 1441 |
| Gene name | colony stimulating factor 3 receptor | |
| Synonyms | CD114|GCSFR|SCN7 | |
| Cytomap | 1p34.3 | |
| Type of gene | protein-coding | |
| Description | granulocyte colony-stimulating factor receptorCD114 antigenG-CSF receptorG-CSF-Rcolony stimulating factor 3 receptor (granulocyte) | |
| Modification date | 20200320 | |
| UniProtAcc | Q99062, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for CSF3R |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_106838(36476745, -), ADediting_106839(36476763, -), ADediting_106840(36476768, -), ADediting_106841(36476785, -), ADediting_106842(36476825, -), ADediting_106843(36476869, -), ADediting_106844(36476878, -), ADediting_106845(36476889, -), ADediting_106846(36476916, -), ADediting_106847(36476919, -), ADediting_106848(36476920, -), ADediting_106849(36476959, -), ADediting_106850(36476961, -), ADediting_106851(36477355, -), ADediting_106852(36477356, -), ADediting_106853(36477370, -), ADediting_106854(36477397, -), ADediting_106855(36477423, -), ADediting_106856(36477816, -), ADediting_106857(36477826, -), ADediting_106858(36477831, -), ADediting_106859(36477832, -), ADediting_106860(36477851, -), ADediting_106861(36477856, -), ADediting_106862(36477870, -), ADediting_106863(36477887, -), ADediting_106864(36477891, -), ADediting_106865(36477897, -), ADediting_106866(36477923, -), ADediting_106867(36477933, -), ADediting_106868(36477935, -), ADediting_106869(36477953, -), ADediting_106870(36477959, -), ADediting_106871(36477984, -), ADediting_106872(36478025, -), ADediting_106873(36478030, -), ADediting_106874(36478031, -), ADediting_106875(36478266, -), ADediting_106876(36478272, -), ADediting_106877(36478284, -), ADediting_106878(36478285, -), ADediting_106879(36478326, -), ADediting_106880(36478346, -), ADediting_106881(36478349, -), ADediting_106882(36478407, -), ADediting_106883(36478417, -), ADediting_106884(36478419, -), ADediting_106885(36478446, -), ADediting_106886(36478472, -), ADediting_106887(36478477, -), ADediting_106888(36478488, -), ADediting_106889(36478493, -), ADediting_106890(36478585, -), ADediting_106891(36478588, -), ADediting_106892(36478591, -), ADediting_106893(36478603, -), ADediting_106894(36478604, -), ADediting_106895(36478645, -), ADediting_106896(36478665, -), ADediting_106897(36478682, -), ADediting_106898(36478768, -), ADediting_106899(36478769, -), ADediting_106900(36478794, -), ADediting_106901(36478799, -), ADediting_106902(36478845, -), ADediting_1519781(36476821, -), ADediting_1519782(36476858, -), ADediting_1519783(36476943, -), ADediting_1519784(36477427, -), ADediting_1519785(36477549, -), ADediting_1519786(36478721, -), |
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RNA editing positional annotations for CSF3R using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_106838 | chr1_36476745_- | intronic |
| ADediting_106839 | chr1_36476763_- | intronic |
| ADediting_106840 | chr1_36476768_- | intronic |
| ADediting_106841 | chr1_36476785_- | intronic |
| ADediting_106842 | chr1_36476825_- | intronic |
| ADediting_106843 | chr1_36476869_- | intronic |
| ADediting_106844 | chr1_36476878_- | intronic |
| ADediting_106845 | chr1_36476889_- | intronic |
| ADediting_106846 | chr1_36476916_- | intronic |
| ADediting_106847 | chr1_36476919_- | intronic |
| ADediting_106848 | chr1_36476920_- | intronic |
| ADediting_106849 | chr1_36476959_- | intronic |
| ADediting_106850 | chr1_36476961_- | intronic |
| ADediting_106851 | chr1_36477355_- | intronic |
| ADediting_106852 | chr1_36477356_- | intronic |
| ADediting_106853 | chr1_36477370_- | intronic |
| ADediting_106854 | chr1_36477397_- | intronic |
| ADediting_106855 | chr1_36477423_- | intronic |
| ADediting_106856 | chr1_36477816_- | intronic |
| ADediting_106857 | chr1_36477826_- | intronic |
| ADediting_106858 | chr1_36477831_- | intronic |
| ADediting_106859 | chr1_36477832_- | intronic |
| ADediting_106860 | chr1_36477851_- | intronic |
| ADediting_106861 | chr1_36477856_- | intronic |
| ADediting_106862 | chr1_36477870_- | intronic |
| ADediting_106863 | chr1_36477887_- | intronic |
| ADediting_106864 | chr1_36477891_- | intronic |
| ADediting_106865 | chr1_36477897_- | intronic |
| ADediting_106866 | chr1_36477923_- | intronic |
| ADediting_106867 | chr1_36477933_- | intronic |
| ADediting_106868 | chr1_36477935_- | intronic |
| ADediting_106869 | chr1_36477953_- | intronic |
| ADediting_106870 | chr1_36477959_- | intronic |
| ADediting_106871 | chr1_36477984_- | intronic |
| ADediting_106872 | chr1_36478025_- | intronic |
| ADediting_106873 | chr1_36478030_- | intronic |
| ADediting_106874 | chr1_36478031_- | intronic |
| ADediting_106875 | chr1_36478266_- | intronic |
| ADediting_106876 | chr1_36478272_- | intronic |
| ADediting_106877 | chr1_36478284_- | intronic |
| ADediting_106878 | chr1_36478285_- | intronic |
| ADediting_106879 | chr1_36478326_- | intronic |
| ADediting_106880 | chr1_36478346_- | intronic |
| ADediting_106881 | chr1_36478349_- | intronic |
| ADediting_106882 | chr1_36478407_- | intronic |
| ADediting_106883 | chr1_36478417_- | intronic |
| ADediting_106884 | chr1_36478419_- | intronic |
| ADediting_106885 | chr1_36478446_- | intronic |
| ADediting_106886 | chr1_36478472_- | intronic |
| ADediting_106887 | chr1_36478477_- | intronic |
| ADediting_106888 | chr1_36478488_- | intronic |
| ADediting_106889 | chr1_36478493_- | intronic |
| ADediting_106890 | chr1_36478585_- | intronic |
| ADediting_106891 | chr1_36478588_- | intronic |
| ADediting_106892 | chr1_36478591_- | intronic |
| ADediting_106893 | chr1_36478603_- | intronic |
| ADediting_106894 | chr1_36478604_- | intronic |
| ADediting_106895 | chr1_36478645_- | intronic |
| ADediting_106896 | chr1_36478665_- | intronic |
| ADediting_106897 | chr1_36478682_- | intronic |
| ADediting_106898 | chr1_36478768_- | intronic |
| ADediting_106899 | chr1_36478769_- | intronic |
| ADediting_106900 | chr1_36478794_- | intronic |
| ADediting_106901 | chr1_36478799_- | intronic |
| ADediting_106902 | chr1_36478845_- | intronic |
| ADediting_1519781 | chr1_36476821_- | intronic |
| ADediting_1519782 | chr1_36476858_- | intronic |
| ADediting_1519783 | chr1_36476943_- | intronic |
| ADediting_1519784 | chr1_36477427_- | intronic |
| ADediting_1519785 | chr1_36477549_- | intronic |
| ADediting_1519786 | chr1_36478721_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_106838 | chr1_36476745_- | SINE | Alu | Name=AluJb |
| ADediting_106839 | chr1_36476763_- | SINE | Alu | Name=AluJb |
| ADediting_106840 | chr1_36476768_- | SINE | Alu | Name=AluJb |
| ADediting_106841 | chr1_36476785_- | SINE | Alu | Name=AluJb |
| ADediting_106842 | chr1_36476825_- | SINE | Alu | Name=AluJb |
| ADediting_106843 | chr1_36476869_- | SINE | Alu | Name=AluJb |
| ADediting_106844 | chr1_36476878_- | SINE | Alu | Name=AluJb |
| ADediting_106845 | chr1_36476889_- | SINE | Alu | Name=AluJb |
| ADediting_106846 | chr1_36476916_- | SINE | Alu | Name=AluJb |
| ADediting_106847 | chr1_36476919_- | SINE | Alu | Name=AluJb |
| ADediting_106848 | chr1_36476920_- | SINE | Alu | Name=AluJb |
| ADediting_106849 | chr1_36476959_- | SINE | Alu | Name=AluJb |
| ADediting_106850 | chr1_36476961_- | SINE | Alu | Name=AluJb |
| ADediting_106851 | chr1_36477355_- | SINE | Alu | Name=AluSx3 |
| ADediting_106852 | chr1_36477356_- | SINE | Alu | Name=AluSx3 |
| ADediting_106853 | chr1_36477370_- | SINE | Alu | Name=AluSx3 |
| ADediting_106854 | chr1_36477397_- | SINE | Alu | Name=AluSx3 |
| ADediting_106855 | chr1_36477423_- | SINE | Alu | Name=AluSx3 |
| ADediting_106856 | chr1_36477816_- | SINE | Alu | Name=AluY |
| ADediting_106857 | chr1_36477826_- | SINE | Alu | Name=AluY |
| ADediting_106858 | chr1_36477831_- | SINE | Alu | Name=AluY |
| ADediting_106859 | chr1_36477832_- | SINE | Alu | Name=AluY |
| ADediting_106860 | chr1_36477851_- | SINE | Alu | Name=AluY |
| ADediting_106861 | chr1_36477856_- | SINE | Alu | Name=AluY |
| ADediting_106862 | chr1_36477870_- | SINE | Alu | Name=AluY |
| ADediting_106863 | chr1_36477887_- | SINE | Alu | Name=AluY |
| ADediting_106864 | chr1_36477891_- | SINE | Alu | Name=AluY |
| ADediting_106865 | chr1_36477897_- | SINE | Alu | Name=AluY |
| ADediting_106866 | chr1_36477923_- | SINE | Alu | Name=AluY |
| ADediting_106867 | chr1_36477933_- | SINE | Alu | Name=AluY |
| ADediting_106868 | chr1_36477935_- | SINE | Alu | Name=AluY |
| ADediting_106869 | chr1_36477953_- | SINE | Alu | Name=AluY |
| ADediting_106870 | chr1_36477959_- | SINE | Alu | Name=AluY |
| ADediting_106871 | chr1_36477984_- | SINE | Alu | Name=AluY |
| ADediting_106872 | chr1_36478025_- | SINE | Alu | Name=AluY |
| ADediting_106873 | chr1_36478030_- | SINE | Alu | Name=AluY |
| ADediting_106874 | chr1_36478031_- | SINE | Alu | Name=AluY |
| ADediting_106875 | chr1_36478266_- | SINE | Alu | Name=AluSx1 |
| ADediting_106876 | chr1_36478272_- | SINE | Alu | Name=AluSx1 |
| ADediting_106877 | chr1_36478284_- | SINE | Alu | Name=AluSx1 |
| ADediting_106878 | chr1_36478285_- | SINE | Alu | Name=AluSx1 |
| ADediting_106879 | chr1_36478326_- | SINE | Alu | Name=AluSx1 |
| ADediting_106880 | chr1_36478346_- | SINE | Alu | Name=AluSx1 |
| ADediting_106881 | chr1_36478349_- | SINE | Alu | Name=AluSx1 |
| ADediting_106882 | chr1_36478407_- | SINE | Alu | Name=AluSx1 |
| ADediting_106883 | chr1_36478417_- | SINE | Alu | Name=AluSx1 |
| ADediting_106884 | chr1_36478419_- | SINE | Alu | Name=AluSx1 |
| ADediting_106885 | chr1_36478446_- | SINE | Alu | Name=AluSx1 |
| ADediting_106886 | chr1_36478472_- | SINE | Alu | Name=AluSx1 |
| ADediting_106887 | chr1_36478477_- | SINE | Alu | Name=AluSx1 |
| ADediting_106888 | chr1_36478488_- | SINE | Alu | Name=AluSx1 |
| ADediting_106889 | chr1_36478493_- | SINE | Alu | Name=AluSx1 |
| ADediting_106890 | chr1_36478585_- | SINE | Alu | Name=AluJb |
| ADediting_106891 | chr1_36478588_- | SINE | Alu | Name=AluJb |
| ADediting_106892 | chr1_36478591_- | SINE | Alu | Name=AluJb |
| ADediting_106893 | chr1_36478603_- | SINE | Alu | Name=AluJb |
| ADediting_106894 | chr1_36478604_- | SINE | Alu | Name=AluJb |
| ADediting_106895 | chr1_36478645_- | SINE | Alu | Name=AluJb |
| ADediting_106896 | chr1_36478665_- | SINE | Alu | Name=AluJb |
| ADediting_106897 | chr1_36478682_- | SINE | Alu | Name=AluJb |
| ADediting_106898 | chr1_36478768_- | SINE | Alu | Name=AluJb |
| ADediting_106899 | chr1_36478769_- | SINE | Alu | Name=AluJb |
| ADediting_106900 | chr1_36478794_- | SINE | Alu | Name=AluJb |
| ADediting_106901 | chr1_36478799_- | SINE | Alu | Name=AluJb |
| ADediting_106902 | chr1_36478845_- | SINE | Alu | Name=AluJb |
| ADediting_1519781 | chr1_36476821_- | SINE | Alu | Name=AluJb |
| ADediting_1519782 | chr1_36476858_- | SINE | Alu | Name=AluJb |
| ADediting_1519783 | chr1_36476943_- | SINE | Alu | Name=AluJb |
| ADediting_1519784 | chr1_36477427_- | SINE | Alu | Name=AluSx3 |
| ADediting_1519785 | chr1_36477549_- | SINE | Alu | Name=AluSx3 |
| ADediting_1519786 | chr1_36478721_- | SINE | Alu | Name=AluJb |
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RNA A-to-I editing events in the alternative splicing sites for CSF3R |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CSF3R |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for CSF3R |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for CSF3R |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_106851 | chr1_36477355_- | ENSG00000119535.17 | ENST00000526980.5 | CSF3R-214 | hsa-miR-3155a | chr1 | 36477351 | 36477357 | 7mer-m8 | 36477350 | 36477371 | 141 | -23.88 |
| ADediting_106851 | chr1_36477355_- | ENSG00000119535.17 | ENST00000526980.5 | CSF3R-214 | hsa-miR-3155b | chr1 | 36477351 | 36477357 | 7mer-m8 | 36477350 | 36477368 | 141 | -22.98 |
| ADediting_106851 | chr1_36477355_- | ENSG00000119535.17 | ENST00000526980.5 | CSF3R-214 | hsa-miR-484 | chr1 | 36477351 | 36477357 | 7mer-m8 | 36477350 | 36477371 | 151 | -23.09 |
| ADediting_106852 | chr1_36477356_- | ENSG00000119535.17 | ENST00000526980.5 | CSF3R-214 | hsa-miR-9900 | chr1 | 36477351 | 36477357 | 7mer-m8 | 36477350 | 36477369 | 155 | -17.58 |
| ADediting_106854 | chr1_36477397_- | ENSG00000119535.17 | ENST00000526980.5 | CSF3R-214 | hsa-miR-128-1-5p | chr1 | 36477391 | 36477397 | 7mer-1a | 36477391 | 36477414 | 141 | -24.95 |
| ADediting_106854 | chr1_36477397_- | ENSG00000119535.17 | ENST00000526980.5 | CSF3R-214 | hsa-miR-6762-5p | chr1 | 36477391 | 36477398 | 8mer-1a | 36477391 | 36477413 | 154 | -25.68 |
| ADediting_106854 | chr1_36477397_- | ENSG00000119535.17 | ENST00000526980.5 | CSF3R-214 | hsa-miR-6845-5p | chr1 | 36477391 | 36477398 | 8mer-1a | 36477391 | 36477410 | 148 | -19.31 |
| ADediting_1519785 | chr1_36477549_- | ENSG00000119535.17 | ENST00000526980.5 | CSF3R-214 | hsa-miR-1292-3p | chr1 | 36477549 | 36477555 | 7mer-m8 | 36477548 | 36477566 | 147 | -25.41 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_106851 | chr1_36477355_- | ENSG00000119535.17 | ENST00000526980.5 | CSF3R-214 | hsa-miR-498-5p | chr1 | 36477355 | 36477361 | 7mer-m8 | 36477354 | 36477376 | 142 | -9.71 |
| ADediting_106852 | chr1_36477356_- | ENSG00000119535.17 | ENST00000526980.5 | CSF3R-214 | hsa-miR-498-5p | chr1 | 36477355 | 36477361 | 7mer-m8 | 36477354 | 36477376 | 142 | -9.71 |
| ADediting_106853 | chr1_36477370_- | ENSG00000119535.17 | ENST00000526980.5 | CSF3R-214 | hsa-miR-1976 | chr1 | 36477365 | 36477372 | 8mer-1a | 36477365 | 36477385 | 149 | -24.39 |
| ADediting_106853 | chr1_36477370_- | ENSG00000119535.17 | ENST00000526980.5 | CSF3R-214 | hsa-miR-6747-3p | chr1 | 36477367 | 36477374 | 8mer-1a | 36477367 | 36477389 | 149 | -22.77 |
| ADediting_106854 | chr1_36477397_- | ENSG00000119535.17 | ENST00000526980.5 | CSF3R-214 | hsa-miR-4489 | chr1 | 36477391 | 36477398 | 8mer-1a | 36477391 | 36477413 | 147 | -24.65 |
| ADediting_106854 | chr1_36477397_- | ENSG00000119535.17 | ENST00000526980.5 | CSF3R-214 | hsa-miR-548v | chr1 | 36477395 | 36477401 | 7mer-m8 | 36477394 | 36477414 | 150 | -21.94 |
| ADediting_106854 | chr1_36477397_- | ENSG00000119535.17 | ENST00000526980.5 | CSF3R-214 | hsa-miR-7151-3p | chr1 | 36477397 | 36477403 | 7mer-m8 | 36477396 | 36477416 | 142 | -18.13 |
| ADediting_106855 | chr1_36477423_- | ENSG00000119535.17 | ENST00000526980.5 | CSF3R-214 | hsa-miR-4735-5p | chr1 | 36477422 | 36477428 | 7mer-m8 | 36477421 | 36477442 | 140 | -4.28 |
| ADediting_1519784 | chr1_36477427_- | ENSG00000119535.17 | ENST00000526980.5 | CSF3R-214 | hsa-miR-4735-5p | chr1 | 36477422 | 36477428 | 7mer-m8 | 36477421 | 36477442 | 140 | -4.28 |
| ADediting_1519785 | chr1_36477549_- | ENSG00000119535.17 | ENST00000526980.5 | CSF3R-214 | hsa-miR-4252 | chr1 | 36477544 | 36477550 | 7mer-m8 | 36477543 | 36477561 | 150 | -20.34 |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for CSF3R |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000526980.5 | lncRNA |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_106851 | ENST00000526980.5 | chr1_36477355_- | 556 | -307.60 | -307.30 | -310.70 |
| ADediting_106852 | ENST00000526980.5 | chr1_36477356_- | 555 | -307.30 | -307.30 | -310.70 |
| ADediting_106853 | ENST00000526980.5 | chr1_36477370_- | 541 | -307.00 | -307.30 | -310.70 |
| ADediting_106854 | ENST00000526980.5 | chr1_36477397_- | 514 | -308.70 | -307.30 | -310.70 |
| ADediting_106855 | ENST00000526980.5 | chr1_36477423_- | 488 | -309.60 | -307.30 | -310.70 |
| ADediting_1519784 | ENST00000526980.5 | chr1_36477427_- | 484 | -307.30 | -307.30 | -310.70 |
| ADediting_1519785 | ENST00000526980.5 | chr1_36477549_- | 362 | -308.50 | -307.30 | -310.70 |
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Relation with ADAR for CSF3R |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_106873 | chr1_36478030_- | 0.0849189466406356 | 0.0980104954711761 | 0.546710108892717 | -0.0343595990625505 | 3.62629167199702e-12 | 0.381316374709511 |
| DLPFC | ADediting_106876 | chr1_36478272_- | 0.171341291370141 | 0.0778884562716978 | 0.662202868677731 | 0.0249095427751651 | 1.5961124161514e-08 | 0.314061286037281 |
| DLPFC | ADediting_106898 | chr1_36478768_- | 0.0876385524695152 | 0.097170066739109 | 0.811292355631995 | -0.0136149805569007 | 6.00239498995231e-08 | 0.301777581363213 |
| DLPFC | ADediting_106900 | chr1_36478794_- | 0.186911269780495 | 0.0751555522407513 | 0.369807679160143 | -0.0511099024921854 | 2.33189845199268e-09 | 0.330962551260586 |
| DLPFC | ADediting_106901 | chr1_36478799_- | 0.144542485113823 | 0.083062587086226 | 0.405950638850022 | -0.0473647854922692 | 3.16103199217723e-11 | 0.365418904870399 |
| TCX | ADediting_106901 | chr1_36478799_- | 0.258826622506069 | 0.0927733503325541 | 0.198059772375033 | -0.105680714645578 | 1.20328069056692e-05 | 0.348996993030039 |
| DLPFC | ADediting_106902 | chr1_36478845_- | 0.0744394608305804 | 0.101467131330531 | 0.777194840342392 | -0.0161361255776941 | 1.58488130161162e-10 | 0.352987647234656 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 0.00510424296304179 | 0.158682991833032 | 0.063671821495195 | 0.105459011839733 | 7.46183914757469e-21 | 0.498226668332113 |
| AC | 2.51326066691479e-20 | 0.54002488274228 | 3.15004842254445e-11 | 0.403908370839386 | 3.65031546655017e-13 | 0.438384776140688 |
| PCC | 0.110320720328486 | 0.115908112625427 | 0.505550626142958 | 0.0484640889722925 | 1.03789558193122e-07 | 0.373377134226728 |
| CER | 3.68131499719676e-07 | 0.400966665521755 | 0.00455206018618451 | 0.230452359531157 | 0.000133322147141151 | 0.306925866491367 |
| TCX | 0.0896996953107243 | 0.13904743645165 | 0.0171812233821976 | -0.194322580655989 | 1.84773785870818e-07 | 0.41026311267454 |
| FP | 0.00329996131830835 | 0.219097703220069 | 0.364357117438959 | 0.0683917550225071 | 1.11110245392243e-11 | 0.480722183063605 |
| IFG | 0.628430965562326 | 0.10174440296137 | 0.973223072137047 | -0.00707541581884484 | 6.47914059791094e-05 | 0.71233865098304 |
| PG | 0.633601013320618 | 0.0351770590404835 | 0.341290651613336 | -0.0701629857278145 | 3.45724130585126e-09 | 0.416203756155618 |
| STG | 0.963458162445682 | 0.00507477203875766 | 0.0278250168129724 | -0.240087023117273 | 3.94399311837987e-07 | 0.520200682500567 |
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Relation with AD stages for CSF3R |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| TCX | ADediting_106858 | chr1_36477831_- | 0.000400348898609932 | 0.337668529078676 |
| TCX | ADediting_106859 | chr1_36477832_- | 0.000962408458932437 | 0.316133196375057 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| TCX | 7.77984778724318e-08 | 0.493268904758015 |
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RelatedDrugs for CSF3R |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| CSF3R | Q99062 | DB00019 | Pegfilgrastim | Granulocyte colony-stimulating factor receptor | biotech | approved |
| CSF3R | Q99062 | DB00099 | Filgrastim | Granulocyte colony-stimulating factor receptor | biotech | approved |
| CSF3R | Q99062 | DB13144 | Lenograstim | Granulocyte colony-stimulating factor receptor | biotech | approved|investigational |
| CSF3R | Q99062 | DB13200 | Lipegfilgrastim | Granulocyte colony-stimulating factor receptor | biotech | approved|investigational |
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RelatedDiseases for CSF3R |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| CSF3R | C0010828 | Cytopenia | 3 | GENOMICS_ENGLAND |
| CSF3R | C0158995 | Congenital anemia | 3 | GENOMICS_ENGLAND |
| CSF3R | C4310764 | NEUTROPENIA, SEVERE CONGENITAL, 7, AUTOSOMAL RECESSIVE | 2 | CTD_human;ORPHANET;UNIPROT |
| CSF3R | C0023518 | Leukocytosis | 1 | CTD_human |
| CSF3R | C0151857 | Pleocytosis | 1 | CTD_human |
| CSF3R | C0543669 | Neutrophilia, Hereditary | 1 | CTD_human;ORPHANET;UNIPROT |
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