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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for COPA |
 Gene summary |
| Gene information | Gene symbol | COPA | Gene ID | 1314 |
| Gene name | COPI coat complex subunit alpha | |
| Synonyms | AILJK|HEP-COP|alpha-COP | |
| Cytomap | 1q23.2 | |
| Type of gene | protein-coding | |
| Description | coatomer subunit alphaalpha coat proteincoatomer protein complex subunit alphaproxeninxenin | |
| Modification date | 20200327 | |
| UniProtAcc | P53621, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| COPA | GO:0030157 | pancreatic juice secretion | 1429581 |
Top |
RNA A-to-I events for COPA |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_37002(160288976, -), ADediting_37003(160302652, -), ADediting_37004(160302693, -), ADediting_37005(160302729, -), ADediting_37006(160302757, -), ADediting_37007(160302759, -), ADediting_37008(160302826, -), ADediting_37009(160302910, -), ADediting_37010(160302928, -), ADediting_37011(160302943, -), ADediting_37012(160302981, -), ADediting_37013(160302988, -), ADediting_37014(160302990, -), ADediting_37015(160302993, -), ADediting_37016(160303033, -), ADediting_37017(160303152, -), ADediting_37018(160303163, -), ADediting_37019(160304100, -), ADediting_37020(160304111, -), ADediting_37021(160304117, -), ADediting_37022(160304126, -), ADediting_37023(160304130, -), ADediting_37024(160304143, -), ADediting_37025(160304147, -), ADediting_37026(160304152, -), ADediting_37027(160304153, -), ADediting_37028(160304178, -), ADediting_37029(160304208, -), ADediting_37030(160304221, -), ADediting_37031(160304232, -), ADediting_37032(160304260, -), ADediting_37033(160304281, -), ADediting_37034(160304286, -), ADediting_37035(160304287, -), ADediting_37036(160304409, -), ADediting_37037(160304421, -), ADediting_37038(160304422, -), ADediting_37039(160304436, -), ADediting_37040(160304501, -), ADediting_37041(160304542, -), ADediting_37042(160304552, -), ADediting_37043(160304564, -), ADediting_37044(160304577, -), ADediting_37045(160304581, -), ADediting_37046(160304582, -), ADediting_37047(160304601, -), ADediting_37048(160304602, -), ADediting_37049(160304617, -), ADediting_37050(160304652, -), ADediting_37051(160313685, -), ADediting_37052(160314506, -), ADediting_37053(160314624, -), ADediting_37054(160324066, -), ADediting_37055(160324106, -), ADediting_37056(160324577, -), ADediting_37057(160326276, -), ADediting_37058(160326292, -), ADediting_37059(160326309, -), ADediting_37060(160326310, -), ADediting_37061(160326372, -), ADediting_37062(160326403, -), ADediting_37063(160326521, -), ADediting_37064(160326734, -), ADediting_37065(160326738, -), ADediting_37066(160326744, -), ADediting_37067(160326756, -), ADediting_37068(160326757, -), ADediting_37069(160326761, -), ADediting_37070(160328044, -), ADediting_37071(160328045, -), ADediting_37072(160328061, -), ADediting_37073(160328085, -), ADediting_37074(160332454, -), ADediting_37075(160333010, -), ADediting_37076(160333056, -), ADediting_37077(160333062, -), ADediting_37078(160333064, -), ADediting_37079(160333089, -), ADediting_37080(160333117, -), ADediting_37081(160333125, -), ADediting_37082(160333127, -), ADediting_37083(160333137, -), ADediting_37084(160333161, -), ADediting_37085(160333166, -), ADediting_37086(160333191, -), ADediting_37087(160333196, -), ADediting_37088(160333197, -), ADediting_37089(160333212, -), ADediting_37090(160337463, -), ADediting_1515935(160326419, -), ADediting_1515936(160328125, -), ADediting_1515937(160328484, -), ADediting_1515938(160333091, -), ADediting_1515939(160333094, -), ADediting_1515940(160333095, -), ADediting_1515941(160333170, -), ADediting_1515942(160333174, -), ADediting_1596742(160289683, -), ADediting_1596743(160289731, -), ADediting_1596744(160289742, -), ADediting_1596745(160289747, -), ADediting_1596746(160289755, -), ADediting_1596747(160304481, -), ADediting_1596748(160331026, -), ADediting_1596749(160333052, -), ADediting_1596750(160333088, -), |
Top |
RNA editing positional annotations for COPA using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| ADediting_37074 | chr1_160332454_- | nonsynonymous SNV | ENST00000649676.1 | c.A37G | p.I13V | 0.022 | 0.021 | -0.84 |
| ADediting_37074 | chr1_160332454_- | nonsynonymous SNV | ENST00000649787.1 | c.A490G | p.I164V | 0.022 | 0.021 | -0.84 |
| ADediting_37074 | chr1_160332454_- | nonsynonymous SNV | ENST00000241704.8 | c.A490G | p.I164V | 0.022 | 0.021 | -0.84 |
| ADediting_37074 | chr1_160332454_- | nonsynonymous SNV | ENST00000648805.1 | c.A490G | p.I164V | 0.022 | 0.021 | -0.84 |
| ADediting_37074 | chr1_160332454_- | nonsynonymous SNV | ENST00000647799.1 | c.A413G | p.Y138C | 0.022 | 0.021 | -0.84 |
| ADediting_37074 | chr1_160332454_- | nonsynonymous SNV | ENST00000647683.1 | c.A490G | p.I164V | 0.022 | 0.021 | -0.84 |
| ADediting_37074 | chr1_160332454_- | nonsynonymous SNV | ENST00000368069.7 | c.A490G | p.I164V | 0.022 | 0.021 | -0.84 |
| ADediting_37074 | chr1_160332454_- | nonsynonymous SNV | ENST00000650154.1 | c.A332G | p.Y111C | 0.022 | 0.021 | -0.84 |
| ADediting_37074 | chr1_160332454_- | nonsynonymous SNV | ENST00000649231.1 | c.A490G | p.I164V | 0.022 | 0.021 | -0.84 |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_37002 | chr1_160288976_- | UTR3 |
| ADediting_37003 | chr1_160302652_- | intronic |
| ADediting_37004 | chr1_160302693_- | intronic |
| ADediting_37005 | chr1_160302729_- | intronic |
| ADediting_37006 | chr1_160302757_- | intronic |
| ADediting_37007 | chr1_160302759_- | intronic |
| ADediting_37008 | chr1_160302826_- | intronic |
| ADediting_37009 | chr1_160302910_- | intronic |
| ADediting_37010 | chr1_160302928_- | intronic |
| ADediting_37011 | chr1_160302943_- | intronic |
| ADediting_37012 | chr1_160302981_- | intronic |
| ADediting_37013 | chr1_160302988_- | intronic |
| ADediting_37014 | chr1_160302990_- | intronic |
| ADediting_37015 | chr1_160302993_- | intronic |
| ADediting_37016 | chr1_160303033_- | intronic |
| ADediting_37017 | chr1_160303152_- | intronic |
| ADediting_37018 | chr1_160303163_- | intronic |
| ADediting_37019 | chr1_160304100_- | intronic |
| ADediting_37020 | chr1_160304111_- | intronic |
| ADediting_37021 | chr1_160304117_- | intronic |
| ADediting_37022 | chr1_160304126_- | intronic |
| ADediting_37023 | chr1_160304130_- | intronic |
| ADediting_37024 | chr1_160304143_- | intronic |
| ADediting_37025 | chr1_160304147_- | intronic |
| ADediting_37026 | chr1_160304152_- | intronic |
| ADediting_37027 | chr1_160304153_- | intronic |
| ADediting_37028 | chr1_160304178_- | intronic |
| ADediting_37029 | chr1_160304208_- | intronic |
| ADediting_37030 | chr1_160304221_- | intronic |
| ADediting_37031 | chr1_160304232_- | intronic |
| ADediting_37032 | chr1_160304260_- | intronic |
| ADediting_37033 | chr1_160304281_- | intronic |
| ADediting_37034 | chr1_160304286_- | intronic |
| ADediting_37035 | chr1_160304287_- | intronic |
| ADediting_37036 | chr1_160304409_- | intronic |
| ADediting_37037 | chr1_160304421_- | intronic |
| ADediting_37038 | chr1_160304422_- | intronic |
| ADediting_37039 | chr1_160304436_- | intronic |
| ADediting_37040 | chr1_160304501_- | intronic |
| ADediting_37041 | chr1_160304542_- | intronic |
| ADediting_37042 | chr1_160304552_- | intronic |
| ADediting_37043 | chr1_160304564_- | intronic |
| ADediting_37044 | chr1_160304577_- | intronic |
| ADediting_37045 | chr1_160304581_- | intronic |
| ADediting_37046 | chr1_160304582_- | intronic |
| ADediting_37047 | chr1_160304601_- | intronic |
| ADediting_37048 | chr1_160304602_- | intronic |
| ADediting_37049 | chr1_160304617_- | intronic |
| ADediting_37050 | chr1_160304652_- | intronic |
| ADediting_37051 | chr1_160313685_- | intronic |
| ADediting_37052 | chr1_160314506_- | intronic |
| ADediting_37053 | chr1_160314624_- | intronic |
| ADediting_37054 | chr1_160324066_- | intronic |
| ADediting_37055 | chr1_160324106_- | intronic |
| ADediting_37056 | chr1_160324577_- | intronic |
| ADediting_37057 | chr1_160326276_- | intronic |
| ADediting_37058 | chr1_160326292_- | intronic |
| ADediting_37059 | chr1_160326309_- | intronic |
| ADediting_37060 | chr1_160326310_- | intronic |
| ADediting_37061 | chr1_160326372_- | intronic |
| ADediting_37062 | chr1_160326403_- | intronic |
| ADediting_37063 | chr1_160326521_- | intronic |
| ADediting_37064 | chr1_160326734_- | intronic |
| ADediting_37065 | chr1_160326738_- | intronic |
| ADediting_37066 | chr1_160326744_- | intronic |
| ADediting_37067 | chr1_160326756_- | intronic |
| ADediting_37068 | chr1_160326757_- | intronic |
| ADediting_37069 | chr1_160326761_- | intronic |
| ADediting_37070 | chr1_160328044_- | intronic |
| ADediting_37071 | chr1_160328045_- | intronic |
| ADediting_37072 | chr1_160328061_- | intronic |
| ADediting_37073 | chr1_160328085_- | intronic |
| ADediting_37074 | chr1_160332454_- | exonic |
| ADediting_37075 | chr1_160333010_- | intronic |
| ADediting_37076 | chr1_160333056_- | intronic |
| ADediting_37077 | chr1_160333062_- | intronic |
| ADediting_37078 | chr1_160333064_- | intronic |
| ADediting_37079 | chr1_160333089_- | intronic |
| ADediting_37080 | chr1_160333117_- | intronic |
| ADediting_37081 | chr1_160333125_- | intronic |
| ADediting_37082 | chr1_160333127_- | intronic |
| ADediting_37083 | chr1_160333137_- | intronic |
| ADediting_37084 | chr1_160333161_- | intronic |
| ADediting_37085 | chr1_160333166_- | intronic |
| ADediting_37086 | chr1_160333191_- | intronic |
| ADediting_37087 | chr1_160333196_- | intronic |
| ADediting_37088 | chr1_160333197_- | intronic |
| ADediting_37089 | chr1_160333212_- | intronic |
| ADediting_37090 | chr1_160337463_- | intronic |
| ADediting_1515935 | chr1_160326419_- | intronic |
| ADediting_1515936 | chr1_160328125_- | intronic |
| ADediting_1515937 | chr1_160328484_- | intronic |
| ADediting_1515938 | chr1_160333091_- | intronic |
| ADediting_1515939 | chr1_160333094_- | intronic |
| ADediting_1515940 | chr1_160333095_- | intronic |
| ADediting_1515941 | chr1_160333170_- | intronic |
| ADediting_1515942 | chr1_160333174_- | intronic |
| ADediting_1596742 | chr1_160289683_- | UTR3 |
| ADediting_1596743 | chr1_160289731_- | UTR3 |
| ADediting_1596744 | chr1_160289742_- | UTR3 |
| ADediting_1596745 | chr1_160289747_- | UTR3 |
| ADediting_1596746 | chr1_160289755_- | UTR3 |
| ADediting_1596747 | chr1_160304481_- | intronic |
| ADediting_1596748 | chr1_160331026_- | intronic |
| ADediting_1596749 | chr1_160333052_- | intronic |
| ADediting_1596750 | chr1_160333088_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_37002 | chr1_160288976_- | SINE | Alu | Name=AluSg7 |
| ADediting_37003 | chr1_160302652_- | SINE | Alu | Name=AluY |
| ADediting_37004 | chr1_160302693_- | SINE | Alu | Name=AluY |
| ADediting_37005 | chr1_160302729_- | SINE | Alu | Name=AluY |
| ADediting_37006 | chr1_160302757_- | SINE | Alu | Name=AluY |
| ADediting_37007 | chr1_160302759_- | SINE | Alu | Name=AluY |
| ADediting_37008 | chr1_160302826_- | SINE | Alu | Name=AluY |
| ADediting_37009 | chr1_160302910_- | SINE | Alu | Name=AluSz |
| ADediting_37010 | chr1_160302928_- | SINE | Alu | Name=AluSz |
| ADediting_37011 | chr1_160302943_- | SINE | Alu | Name=AluSz |
| ADediting_37012 | chr1_160302981_- | SINE | Alu | Name=AluSz |
| ADediting_37013 | chr1_160302988_- | SINE | Alu | Name=AluSz |
| ADediting_37014 | chr1_160302990_- | SINE | Alu | Name=AluSz |
| ADediting_37015 | chr1_160302993_- | SINE | Alu | Name=AluSz |
| ADediting_37016 | chr1_160303033_- | SINE | Alu | Name=AluSz |
| ADediting_37017 | chr1_160303152_- | SINE | Alu | Name=AluSz |
| ADediting_37018 | chr1_160303163_- | SINE | Alu | Name=AluSz |
| ADediting_37019 | chr1_160304100_- | SINE | Alu | Name=AluSp |
| ADediting_37020 | chr1_160304111_- | SINE | Alu | Name=AluSp |
| ADediting_37021 | chr1_160304117_- | SINE | Alu | Name=AluSp |
| ADediting_37022 | chr1_160304126_- | SINE | Alu | Name=AluSp |
| ADediting_37023 | chr1_160304130_- | SINE | Alu | Name=AluSp |
| ADediting_37024 | chr1_160304143_- | SINE | Alu | Name=AluSp |
| ADediting_37025 | chr1_160304147_- | SINE | Alu | Name=AluSp |
| ADediting_37026 | chr1_160304152_- | SINE | Alu | Name=AluSp |
| ADediting_37027 | chr1_160304153_- | SINE | Alu | Name=AluSp |
| ADediting_37028 | chr1_160304178_- | SINE | Alu | Name=AluSp |
| ADediting_37029 | chr1_160304208_- | SINE | Alu | Name=AluSp |
| ADediting_37030 | chr1_160304221_- | SINE | Alu | Name=AluSp |
| ADediting_37031 | chr1_160304232_- | SINE | Alu | Name=AluSp |
| ADediting_37032 | chr1_160304260_- | SINE | Alu | Name=AluSp |
| ADediting_37033 | chr1_160304281_- | SINE | Alu | Name=AluSp |
| ADediting_37034 | chr1_160304286_- | SINE | Alu | Name=AluSp |
| ADediting_37035 | chr1_160304287_- | SINE | Alu | Name=AluSp |
| ADediting_37036 | chr1_160304409_- | SINE | Alu | Name=AluSg |
| ADediting_37037 | chr1_160304421_- | SINE | Alu | Name=AluSg |
| ADediting_37038 | chr1_160304422_- | SINE | Alu | Name=AluSg |
| ADediting_37039 | chr1_160304436_- | SINE | Alu | Name=AluSg |
| ADediting_37040 | chr1_160304501_- | SINE | Alu | Name=AluSg |
| ADediting_37041 | chr1_160304542_- | SINE | Alu | Name=AluSg |
| ADediting_37042 | chr1_160304552_- | SINE | Alu | Name=AluSg |
| ADediting_37043 | chr1_160304564_- | SINE | Alu | Name=AluSg |
| ADediting_37044 | chr1_160304577_- | SINE | Alu | Name=AluSg |
| ADediting_37045 | chr1_160304581_- | SINE | Alu | Name=AluSg |
| ADediting_37046 | chr1_160304582_- | SINE | Alu | Name=AluSg |
| ADediting_37047 | chr1_160304601_- | SINE | Alu | Name=AluSg |
| ADediting_37048 | chr1_160304602_- | SINE | Alu | Name=AluSg |
| ADediting_37049 | chr1_160304617_- | SINE | Alu | Name=AluSg |
| ADediting_37050 | chr1_160304652_- | SINE | Alu | Name=AluSg |
| ADediting_37051 | chr1_160313685_- | SINE | Alu | Name=AluY |
| ADediting_37052 | chr1_160314506_- | SINE | Alu | Name=AluJb |
| ADediting_37053 | chr1_160314624_- | SINE | Alu | Name=AluJb |
| ADediting_37054 | chr1_160324066_- | SINE | Alu | Name=AluSg7 |
| ADediting_37055 | chr1_160324106_- | SINE | Alu | Name=AluSg7 |
| ADediting_37056 | chr1_160324577_- | SINE | Alu | Name=AluJr |
| ADediting_37057 | chr1_160326276_- | SINE | Alu | Name=AluJb |
| ADediting_37058 | chr1_160326292_- | SINE | Alu | Name=AluJb |
| ADediting_37059 | chr1_160326309_- | SINE | Alu | Name=AluJb |
| ADediting_37060 | chr1_160326310_- | SINE | Alu | Name=AluJb |
| ADediting_37061 | chr1_160326372_- | SINE | Alu | Name=AluJb |
| ADediting_37062 | chr1_160326403_- | SINE | Alu | Name=AluJb |
| ADediting_37063 | chr1_160326521_- | SINE | Alu | Name=AluJb |
| ADediting_37075 | chr1_160333010_- | SINE | Alu | Name=AluSx |
| ADediting_37076 | chr1_160333056_- | SINE | Alu | Name=AluSx |
| ADediting_37077 | chr1_160333062_- | SINE | Alu | Name=AluSx |
| ADediting_37078 | chr1_160333064_- | SINE | Alu | Name=AluSx |
| ADediting_37079 | chr1_160333089_- | SINE | Alu | Name=AluSx |
| ADediting_37080 | chr1_160333117_- | SINE | Alu | Name=AluSx |
| ADediting_37081 | chr1_160333125_- | SINE | Alu | Name=AluSx |
| ADediting_37082 | chr1_160333127_- | SINE | Alu | Name=AluSx |
| ADediting_37083 | chr1_160333137_- | SINE | Alu | Name=AluSx |
| ADediting_37084 | chr1_160333161_- | SINE | Alu | Name=AluSx |
| ADediting_37085 | chr1_160333166_- | SINE | Alu | Name=AluSx |
| ADediting_37086 | chr1_160333191_- | SINE | Alu | Name=AluSx |
| ADediting_37087 | chr1_160333196_- | SINE | Alu | Name=AluSx |
| ADediting_37088 | chr1_160333197_- | SINE | Alu | Name=AluSx |
| ADediting_37089 | chr1_160333212_- | SINE | Alu | Name=AluSx |
| ADediting_37090 | chr1_160337463_- | SINE | Alu | Name=AluSx |
| ADediting_1515935 | chr1_160326419_- | SINE | Alu | Name=AluJb |
| ADediting_1515938 | chr1_160333091_- | SINE | Alu | Name=AluSx |
| ADediting_1515939 | chr1_160333094_- | SINE | Alu | Name=AluSx |
| ADediting_1515940 | chr1_160333095_- | SINE | Alu | Name=AluSx |
| ADediting_1515941 | chr1_160333170_- | SINE | Alu | Name=AluSx |
| ADediting_1515942 | chr1_160333174_- | SINE | Alu | Name=AluSx |
| ADediting_1596742 | chr1_160289683_- | SINE | Alu | Name=AluSz6 |
| ADediting_1596743 | chr1_160289731_- | SINE | Alu | Name=AluSz6 |
| ADediting_1596744 | chr1_160289742_- | SINE | Alu | Name=AluSz6 |
| ADediting_1596745 | chr1_160289747_- | SINE | Alu | Name=AluSz6 |
| ADediting_1596746 | chr1_160289755_- | SINE | Alu | Name=AluSz6 |
| ADediting_1596747 | chr1_160304481_- | SINE | Alu | Name=AluSg |
| ADediting_1596748 | chr1_160331026_- | SINE | Alu | Name=AluSx |
| ADediting_1596749 | chr1_160333052_- | SINE | Alu | Name=AluSx |
| ADediting_1596750 | chr1_160333088_- | SINE | Alu | Name=AluSx |
Top |
RNA A-to-I editing events in the alternative splicing sites for COPA |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for COPA |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for COPA |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
 |
Top |
The effects of the RNA editing to the miRNA binding sites for COPA |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1596742 | chr1_160289683_- | ENSG00000122218.16 | ENST00000241704.8 | COPA-201 | hsa-miR-4726-3p | chr1 | 160289680 | 160289687 | 8mer-1a | 160289680 | 160289701 | 150 | -19.15 |
| ADediting_1596742 | chr1_160289683_- | ENSG00000122218.16 | ENST00000368069.7 | COPA-202 | hsa-miR-4726-3p | chr1 | 160289680 | 160289687 | 8mer-1a | 160289680 | 160289701 | 150 | -19.15 |
| ADediting_1596742 | chr1_160289683_- | ENSG00000122218.16 | ENST00000647683.1 | COPA-208 | hsa-miR-4726-3p | chr1 | 160289680 | 160289687 | 8mer-1a | 160289680 | 160289701 | 150 | -19.15 |
| ADediting_1596742 | chr1_160289683_- | ENSG00000122218.16 | ENST00000648280.1 | COPA-212 | hsa-miR-4726-3p | chr1 | 160289680 | 160289687 | 8mer-1a | 160289680 | 160289701 | 150 | -19.15 |
| ADediting_1596742 | chr1_160289683_- | ENSG00000122218.16 | ENST00000649676.1 | COPA-217 | hsa-miR-4726-3p | chr1 | 160289680 | 160289687 | 8mer-1a | 160289680 | 160289701 | 150 | -19.15 |
| ADediting_1596742 | chr1_160289683_- | ENSG00000122218.16 | ENST00000649787.1 | COPA-218 | hsa-miR-4726-3p | chr1 | 160289680 | 160289687 | 8mer-1a | 160289680 | 160289701 | 150 | -19.15 |
| ADediting_1596743 | chr1_160289731_- | ENSG00000122218.16 | ENST00000241704.8 | COPA-201 | hsa-miR-7151-3p | chr1 | 160289729 | 160289735 | 7mer-m8 | 160289728 | 160289746 | 144 | -17.88 |
| ADediting_1596743 | chr1_160289731_- | ENSG00000122218.16 | ENST00000368069.7 | COPA-202 | hsa-miR-7151-3p | chr1 | 160289729 | 160289735 | 7mer-m8 | 160289728 | 160289746 | 144 | -17.88 |
| ADediting_1596743 | chr1_160289731_- | ENSG00000122218.16 | ENST00000647683.1 | COPA-208 | hsa-miR-7151-3p | chr1 | 160289729 | 160289735 | 7mer-m8 | 160289728 | 160289746 | 144 | -17.88 |
| ADediting_1596743 | chr1_160289731_- | ENSG00000122218.16 | ENST00000648280.1 | COPA-212 | hsa-miR-7151-3p | chr1 | 160289729 | 160289735 | 7mer-m8 | 160289728 | 160289746 | 144 | -17.88 |
| ADediting_1596743 | chr1_160289731_- | ENSG00000122218.16 | ENST00000649676.1 | COPA-217 | hsa-miR-7151-3p | chr1 | 160289729 | 160289735 | 7mer-m8 | 160289728 | 160289746 | 144 | -17.88 |
| ADediting_1596743 | chr1_160289731_- | ENSG00000122218.16 | ENST00000649787.1 | COPA-218 | hsa-miR-7151-3p | chr1 | 160289729 | 160289735 | 7mer-m8 | 160289728 | 160289746 | 144 | -17.88 |
| ADediting_1596744 | chr1_160289742_- | ENSG00000122218.16 | ENST00000241704.8 | COPA-201 | hsa-miR-4715-3p | chr1 | 160289739 | 160289745 | 7mer-m8 | 160289738 | 160289760 | 143 | -16.96 |
| ADediting_1596744 | chr1_160289742_- | ENSG00000122218.16 | ENST00000368069.7 | COPA-202 | hsa-miR-4715-3p | chr1 | 160289739 | 160289745 | 7mer-m8 | 160289738 | 160289760 | 143 | -16.96 |
| ADediting_1596744 | chr1_160289742_- | ENSG00000122218.16 | ENST00000647683.1 | COPA-208 | hsa-miR-4715-3p | chr1 | 160289739 | 160289745 | 7mer-m8 | 160289738 | 160289760 | 143 | -16.96 |
| ADediting_1596744 | chr1_160289742_- | ENSG00000122218.16 | ENST00000648280.1 | COPA-212 | hsa-miR-4715-3p | chr1 | 160289739 | 160289745 | 7mer-m8 | 160289738 | 160289760 | 143 | -16.96 |
| ADediting_1596744 | chr1_160289742_- | ENSG00000122218.16 | ENST00000649676.1 | COPA-217 | hsa-miR-4715-3p | chr1 | 160289739 | 160289745 | 7mer-m8 | 160289738 | 160289760 | 143 | -16.96 |
| ADediting_1596744 | chr1_160289742_- | ENSG00000122218.16 | ENST00000649787.1 | COPA-218 | hsa-miR-4715-3p | chr1 | 160289739 | 160289745 | 7mer-m8 | 160289738 | 160289760 | 143 | -16.96 |
| ADediting_1596746 | chr1_160289755_- | ENSG00000122218.16 | ENST00000241704.8 | COPA-201 | hsa-miR-1972 | chr1 | 160289750 | 160289756 | 7mer-m8 | 160289749 | 160289770 | 141 | -16.64 |
| ADediting_1596746 | chr1_160289755_- | ENSG00000122218.16 | ENST00000368069.7 | COPA-202 | hsa-miR-1972 | chr1 | 160289750 | 160289756 | 7mer-m8 | 160289749 | 160289770 | 141 | -16.64 |
| ADediting_1596746 | chr1_160289755_- | ENSG00000122218.16 | ENST00000647683.1 | COPA-208 | hsa-miR-1972 | chr1 | 160289750 | 160289756 | 7mer-m8 | 160289749 | 160289770 | 141 | -16.64 |
| ADediting_1596746 | chr1_160289755_- | ENSG00000122218.16 | ENST00000648280.1 | COPA-212 | hsa-miR-1972 | chr1 | 160289750 | 160289756 | 7mer-m8 | 160289749 | 160289770 | 141 | -16.64 |
| ADediting_1596746 | chr1_160289755_- | ENSG00000122218.16 | ENST00000649676.1 | COPA-217 | hsa-miR-1972 | chr1 | 160289750 | 160289756 | 7mer-m8 | 160289749 | 160289770 | 141 | -16.64 |
| ADediting_1596746 | chr1_160289755_- | ENSG00000122218.16 | ENST00000649787.1 | COPA-218 | hsa-miR-1972 | chr1 | 160289750 | 160289756 | 7mer-m8 | 160289749 | 160289770 | 141 | -16.64 |
| ADediting_37002 | chr1_160288976_- | ENSG00000122218.16 | ENST00000241704.8 | COPA-201 | hsa-miR-1248 | chr1 | 160288974 | 160288981 | 8mer-1a | 160288974 | 160289000 | 144 | -11.51 |
| ADediting_37002 | chr1_160288976_- | ENSG00000122218.16 | ENST00000241704.8 | COPA-201 | hsa-miR-6868-3p | chr1 | 160288973 | 160288980 | 8mer-1a | 160288973 | 160288992 | 152 | -13.07 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1596742 | chr1_160289683_- | ENSG00000122218.16 | ENST00000241704.8 | COPA-201 | hsa-miR-5571-3p | chr1 | 160289680 | 160289686 | 7mer-m8 | 160289679 | 160289702 | 143 | -15.68 |
| ADediting_1596742 | chr1_160289683_- | ENSG00000122218.16 | ENST00000368069.7 | COPA-202 | hsa-miR-5571-3p | chr1 | 160289680 | 160289686 | 7mer-m8 | 160289679 | 160289702 | 143 | -15.68 |
| ADediting_1596742 | chr1_160289683_- | ENSG00000122218.16 | ENST00000647683.1 | COPA-208 | hsa-miR-5571-3p | chr1 | 160289680 | 160289686 | 7mer-m8 | 160289679 | 160289702 | 143 | -15.68 |
| ADediting_1596742 | chr1_160289683_- | ENSG00000122218.16 | ENST00000648280.1 | COPA-212 | hsa-miR-5571-3p | chr1 | 160289680 | 160289686 | 7mer-m8 | 160289679 | 160289702 | 143 | -15.68 |
| ADediting_1596742 | chr1_160289683_- | ENSG00000122218.16 | ENST00000649676.1 | COPA-217 | hsa-miR-5571-3p | chr1 | 160289680 | 160289686 | 7mer-m8 | 160289679 | 160289702 | 143 | -15.68 |
| ADediting_1596742 | chr1_160289683_- | ENSG00000122218.16 | ENST00000649787.1 | COPA-218 | hsa-miR-5571-3p | chr1 | 160289680 | 160289686 | 7mer-m8 | 160289679 | 160289702 | 143 | -15.68 |
| ADediting_1596743 | chr1_160289731_- | ENSG00000122218.16 | ENST00000241704.8 | COPA-201 | hsa-miR-625-3p | chr1 | 160289727 | 160289733 | 7mer-m8 | 160289726 | 160289747 | 140 | -10.64 |
| ADediting_1596743 | chr1_160289731_- | ENSG00000122218.16 | ENST00000368069.7 | COPA-202 | hsa-miR-625-3p | chr1 | 160289727 | 160289733 | 7mer-m8 | 160289726 | 160289747 | 140 | -10.64 |
| ADediting_1596743 | chr1_160289731_- | ENSG00000122218.16 | ENST00000647683.1 | COPA-208 | hsa-miR-625-3p | chr1 | 160289727 | 160289733 | 7mer-m8 | 160289726 | 160289747 | 140 | -10.64 |
| ADediting_1596743 | chr1_160289731_- | ENSG00000122218.16 | ENST00000648280.1 | COPA-212 | hsa-miR-625-3p | chr1 | 160289727 | 160289733 | 7mer-m8 | 160289726 | 160289747 | 140 | -10.64 |
| ADediting_1596743 | chr1_160289731_- | ENSG00000122218.16 | ENST00000649676.1 | COPA-217 | hsa-miR-625-3p | chr1 | 160289727 | 160289733 | 7mer-m8 | 160289726 | 160289747 | 140 | -10.64 |
| ADediting_1596743 | chr1_160289731_- | ENSG00000122218.16 | ENST00000649787.1 | COPA-218 | hsa-miR-625-3p | chr1 | 160289727 | 160289733 | 7mer-m8 | 160289726 | 160289747 | 140 | -10.64 |
| ADediting_1596745 | chr1_160289747_- | ENSG00000122218.16 | ENST00000241704.8 | COPA-201 | hsa-miR-5006-5p | chr1 | 160289747 | 160289753 | 7mer-m8 | 160289746 | 160289766 | 140 | -13.55 |
| ADediting_1596745 | chr1_160289747_- | ENSG00000122218.16 | ENST00000241704.8 | COPA-201 | hsa-miR-6872-3p | chr1 | 160289744 | 160289750 | 7mer-m8 | 160289743 | 160289763 | 140 | -13.34 |
| ADediting_1596745 | chr1_160289747_- | ENSG00000122218.16 | ENST00000368069.7 | COPA-202 | hsa-miR-5006-5p | chr1 | 160289747 | 160289753 | 7mer-m8 | 160289746 | 160289766 | 140 | -13.55 |
| ADediting_1596745 | chr1_160289747_- | ENSG00000122218.16 | ENST00000368069.7 | COPA-202 | hsa-miR-6872-3p | chr1 | 160289744 | 160289750 | 7mer-m8 | 160289743 | 160289763 | 140 | -13.34 |
| ADediting_1596745 | chr1_160289747_- | ENSG00000122218.16 | ENST00000647683.1 | COPA-208 | hsa-miR-5006-5p | chr1 | 160289747 | 160289753 | 7mer-m8 | 160289746 | 160289766 | 140 | -13.55 |
| ADediting_1596745 | chr1_160289747_- | ENSG00000122218.16 | ENST00000647683.1 | COPA-208 | hsa-miR-6872-3p | chr1 | 160289744 | 160289750 | 7mer-m8 | 160289743 | 160289763 | 140 | -13.34 |
| ADediting_1596745 | chr1_160289747_- | ENSG00000122218.16 | ENST00000648280.1 | COPA-212 | hsa-miR-5006-5p | chr1 | 160289747 | 160289753 | 7mer-m8 | 160289746 | 160289766 | 140 | -13.55 |
| ADediting_1596745 | chr1_160289747_- | ENSG00000122218.16 | ENST00000648280.1 | COPA-212 | hsa-miR-6872-3p | chr1 | 160289744 | 160289750 | 7mer-m8 | 160289743 | 160289763 | 140 | -13.34 |
| ADediting_1596745 | chr1_160289747_- | ENSG00000122218.16 | ENST00000649676.1 | COPA-217 | hsa-miR-5006-5p | chr1 | 160289747 | 160289753 | 7mer-m8 | 160289746 | 160289766 | 140 | -13.55 |
| ADediting_1596745 | chr1_160289747_- | ENSG00000122218.16 | ENST00000649676.1 | COPA-217 | hsa-miR-6872-3p | chr1 | 160289744 | 160289750 | 7mer-m8 | 160289743 | 160289763 | 140 | -13.34 |
| ADediting_1596745 | chr1_160289747_- | ENSG00000122218.16 | ENST00000649787.1 | COPA-218 | hsa-miR-5006-5p | chr1 | 160289747 | 160289753 | 7mer-m8 | 160289746 | 160289766 | 140 | -13.55 |
| ADediting_1596745 | chr1_160289747_- | ENSG00000122218.16 | ENST00000649787.1 | COPA-218 | hsa-miR-6872-3p | chr1 | 160289744 | 160289750 | 7mer-m8 | 160289743 | 160289763 | 140 | -13.34 |
| ADediting_1596746 | chr1_160289755_- | ENSG00000122218.16 | ENST00000241704.8 | COPA-201 | hsa-miR-4735-5p | chr1 | 160289754 | 160289760 | 7mer-m8 | 160289753 | 160289774 | 145 | -4.28 |
| ADediting_1596746 | chr1_160289755_- | ENSG00000122218.16 | ENST00000368069.7 | COPA-202 | hsa-miR-4735-5p | chr1 | 160289754 | 160289760 | 7mer-m8 | 160289753 | 160289774 | 145 | -4.28 |
| ADediting_1596746 | chr1_160289755_- | ENSG00000122218.16 | ENST00000647683.1 | COPA-208 | hsa-miR-4735-5p | chr1 | 160289754 | 160289760 | 7mer-m8 | 160289753 | 160289774 | 145 | -4.28 |
| ADediting_1596746 | chr1_160289755_- | ENSG00000122218.16 | ENST00000648280.1 | COPA-212 | hsa-miR-4735-5p | chr1 | 160289754 | 160289760 | 7mer-m8 | 160289753 | 160289774 | 145 | -4.28 |
| ADediting_1596746 | chr1_160289755_- | ENSG00000122218.16 | ENST00000649676.1 | COPA-217 | hsa-miR-4735-5p | chr1 | 160289754 | 160289760 | 7mer-m8 | 160289753 | 160289774 | 145 | -4.28 |
| ADediting_1596746 | chr1_160289755_- | ENSG00000122218.16 | ENST00000649787.1 | COPA-218 | hsa-miR-4735-5p | chr1 | 160289754 | 160289760 | 7mer-m8 | 160289753 | 160289774 | 145 | -4.28 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_843620 | chr2_207754818_+ | ENSG00000122218.16 | ENST00000241704.8 | COPA-201 | hsa-miR-4775 | chr1 | 160288594 | 160288600 | 7mer-m8 | 160288594 | 160288615 | 151 | -5.75 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| Differentially expressed gene-miRNA network |
Top |
The effects of the RNA editing to the stability of the RNA structures for COPA |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000241704.8 | protein_coding |  |  |
| ENST00000649676.1 | protein_coding |  |  |
| ENST00000368069.7 | protein_coding |  |  |
| ENST00000649787.1 | protein_coding |  |  |
| ENST00000647683.1 | protein_coding |  |  |
| ENST00000647899.1 | protein_coding |  |  |
| ENST00000648280.1 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_37002 | ENST00000241704.8 | chr1_160288976_- | 4936 | -1663.50 | -1662.40 | -1675.20 |
| ADediting_1596742 | ENST00000241704.8 | chr1_160289683_- | 4229 | -1663.90 | -1662.40 | -1675.20 |
| ADediting_1596743 | ENST00000241704.8 | chr1_160289731_- | 4181 | -1664.20 | -1662.40 | -1675.20 |
| ADediting_1596744 | ENST00000241704.8 | chr1_160289742_- | 4170 | -1664.00 | -1662.40 | -1675.20 |
| ADediting_1596745 | ENST00000241704.8 | chr1_160289747_- | 4165 | -1662.00 | -1662.40 | -1675.20 |
| ADediting_1596746 | ENST00000241704.8 | chr1_160289755_- | 4157 | -1662.90 | -1662.40 | -1675.20 |
| ADediting_37074 | ENST00000241704.8 | chr1_160332454_- | 570 | -1666.60 | -1662.40 | -1675.20 |
| ADediting_1596742 | ENST00000649676.1 | chr1_160289683_- | 3549 | -1291.30 | -1290.20 | -1297.30 |
| ADediting_1596743 | ENST00000649676.1 | chr1_160289731_- | 3501 | -1292.00 | -1290.20 | -1297.30 |
| ADediting_1596744 | ENST00000649676.1 | chr1_160289742_- | 3490 | -1291.80 | -1290.20 | -1297.30 |
| ADediting_1596745 | ENST00000649676.1 | chr1_160289747_- | 3485 | -1289.80 | -1290.20 | -1297.30 |
| ADediting_1596746 | ENST00000649676.1 | chr1_160289755_- | 3477 | -1290.70 | -1290.20 | -1297.30 |
| ADediting_37074 | ENST00000649676.1 | chr1_160332454_- | 37 | -1289.70 | -1290.20 | -1297.30 |
| ADediting_1596742 | ENST00000368069.7 | chr1_160289683_- | 4254 | -1506.90 | -1505.80 | -1515.60 |
| ADediting_1596743 | ENST00000368069.7 | chr1_160289731_- | 4206 | -1507.60 | -1505.80 | -1515.60 |
| ADediting_1596744 | ENST00000368069.7 | chr1_160289742_- | 4195 | -1507.40 | -1505.80 | -1515.60 |
| ADediting_1596745 | ENST00000368069.7 | chr1_160289747_- | 4190 | -1505.40 | -1505.80 | -1515.60 |
| ADediting_1596746 | ENST00000368069.7 | chr1_160289755_- | 4182 | -1506.30 | -1505.80 | -1515.60 |
| ADediting_37074 | ENST00000368069.7 | chr1_160332454_- | 568 | -1508.00 | -1505.80 | -1515.60 |
| ADediting_1596742 | ENST00000649787.1 | chr1_160289683_- | 4177 | -1481.20 | -1480.10 | -1491.90 |
| ADediting_1596743 | ENST00000649787.1 | chr1_160289731_- | 4129 | -1481.90 | -1480.10 | -1491.90 |
| ADediting_1596744 | ENST00000649787.1 | chr1_160289742_- | 4118 | -1481.70 | -1480.10 | -1491.90 |
| ADediting_1596745 | ENST00000649787.1 | chr1_160289747_- | 4113 | -1479.70 | -1480.10 | -1491.90 |
| ADediting_1596746 | ENST00000649787.1 | chr1_160289755_- | 4105 | -1480.60 | -1480.10 | -1491.90 |
| ADediting_37074 | ENST00000649787.1 | chr1_160332454_- | 578 | -1484.30 | -1480.10 | -1491.90 |
| ADediting_1596742 | ENST00000647683.1 | chr1_160289683_- | 4171 | -1389.70 | -1388.60 | -1400.40 |
| ADediting_1596743 | ENST00000647683.1 | chr1_160289731_- | 4123 | -1390.40 | -1388.60 | -1400.40 |
| ADediting_1596744 | ENST00000647683.1 | chr1_160289742_- | 4112 | -1390.20 | -1388.60 | -1400.40 |
| ADediting_1596745 | ENST00000647683.1 | chr1_160289747_- | 4107 | -1388.20 | -1388.60 | -1400.40 |
| ADediting_1596746 | ENST00000647683.1 | chr1_160289755_- | 4099 | -1389.10 | -1388.60 | -1400.40 |
| ADediting_37074 | ENST00000647683.1 | chr1_160332454_- | 572 | -1392.80 | -1388.60 | -1400.40 |
| ADediting_37074 | ENST00000647899.1 | chr1_160332454_- | 93 | -629.60 | -627.30 | -629.60 |
| ADediting_1596742 | ENST00000648280.1 | chr1_160289683_- | 1831 | -706.60 | -705.50 | -713.10 |
| ADediting_1596743 | ENST00000648280.1 | chr1_160289731_- | 1783 | -707.30 | -705.50 | -713.10 |
| ADediting_1596744 | ENST00000648280.1 | chr1_160289742_- | 1772 | -707.10 | -705.50 | -713.10 |
| ADediting_1596745 | ENST00000648280.1 | chr1_160289747_- | 1767 | -705.10 | -705.50 | -713.10 |
| ADediting_1596746 | ENST00000648280.1 | chr1_160289755_- | 1759 | -706.00 | -705.50 | -713.10 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for COPA |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_37019 | chr1_160304100_- | 5.7831907014404e-05 | 0.226348243883832 | 0.0501374182364602 | 0.111355398804162 | 1.39330619648543e-12 | 0.38807324690087 |
| DLPFC | ADediting_37021 | chr1_160304117_- | 0.00733094882487242 | 0.152022642668918 | 0.495278346923188 | 0.038873856762101 | 6.10905184533517e-15 | 0.423763220599903 |
| DLPFC | ADediting_37036 | chr1_160304409_- | 0.00172991578971434 | 0.177251058707965 | 0.517005870864703 | 0.0369387512948467 | 1.94093706946247e-23 | 0.525816305634337 |
| DLPFC | ADediting_37037 | chr1_160304421_- | 0.0131987405764056 | 0.140629380344779 | 0.49280663901206 | 0.0390968035215105 | 1.99499532572153e-12 | 0.385555709798923 |
| TCX | ADediting_37065 | chr1_160326738_- | 0.171467687879728 | 0.112241946381618 | 0.0476847975110562 | -0.161965695217118 | 1.33790466030958e-05 | 0.347265296533053 |
| TCX | ADediting_37067 | chr1_160326756_- | 0.714400080127661 | -0.0301251719184497 | 0.000275745856861235 | -0.292877441587339 | 5.11128081236927e-08 | 0.426878024852445 |
| TCX | ADediting_37072 | chr1_160328061_- | 0.171196382737849 | 0.112312630436765 | 0.0805054553701884 | -0.143165658739752 | 2.19351131987815e-08 | 0.437346657810762 |
| AC | ADediting_37074 | chr1_160332454_- | 0.00733989466348769 | 0.169186155500655 | 0.376850948404655 | 0.056128156742669 | 8.05842583523635e-19 | 0.521285996997087 |
| PCC | ADediting_37074 | chr1_160332454_- | 0.00294641766350739 | -0.214044566043957 | 5.76264179605831e-05 | -0.286790340272542 | 2.46432115791289e-08 | 0.389924500018443 |
| IFG | ADediting_37074 | chr1_160332454_- | 0.929310122864111 | 0.0186983634748114 | 0.898952464673522 | -0.0267626244486131 | 0.014500943121914 | 0.482812598533711 |
| STG | ADediting_37074 | chr1_160332454_- | 0.0297126858591693 | -0.23734775608692 | 0.000221032790692278 | -0.392588504017829 | 0.00191035692612982 | 0.333883355079105 |
| DLPFC | ADediting_37078 | chr1_160333064_- | 0.0111000000404241 | 0.144064695578669 | 0.122526038444275 | 0.0878931625344511 | 5.29863920877314e-10 | 0.343313468978288 |
| TCX | ADediting_37080 | chr1_160333117_- | 0.445555923311933 | 0.0627495351622255 | 0.0155035499549694 | -0.19732816495097 | 2.77755561742859e-07 | 0.404799982197628 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 2.88777469245528e-90 | 0.856029365894834 | 3.73903785173495e-72 | 0.806108527730471 | 1.28592641506204e-08 | 0.316013055734139 |
| AC | 2.81413432159714e-130 | 0.952697647551214 | 2.21397789029196e-79 | 0.87321178370326 | 5.25951564983777e-10 | 0.379905431977334 |
| PCC | 1.73020315899401e-68 | 0.895832624510919 | 2.01257763371355e-67 | 0.892932240372722 | 0.027424055206482 | 0.1596025246331 |
| CER | 7.76744088984871e-36 | 0.808092121615545 | 1.46373985389067e-17 | 0.62397384290592 | 0.178053437939569 | 0.110550971297607 |
| TCX | 1.60320760441647e-54 | 0.897622358793983 | 1.27201396584106e-16 | 0.609451282778367 | 0.000150353524401072 | 0.304650369381849 |
| FP | 1.96190510230856e-40 | 0.79725601858481 | 4.41149480699466e-22 | 0.642208819294564 | 0.00812336126296233 | 0.197822650618466 |
| IFG | 2.69952680133487e-08 | 0.863670683759644 | 0.000696488776446853 | 0.632273635775918 | 0.0923127322431328 | 0.343912857797768 |
| PG | 3.70503200827834e-77 | 0.920797191085601 | 1.85951400224942e-23 | 0.647184528244381 | 0.306672297172352 | 0.0753548657455956 |
| STG | 1.71563616004046e-20 | 0.807515564768065 | 4.01069397408138e-14 | 0.709911581656566 | 0.83280923670715 | 0.0233800765371599 |
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Relation with AD stages for COPA |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| TCX | ADediting_37074 | chr1_160332454_- | 6.17887956700306e-06 | 0.423239334229697 |
| IFG | ADediting_37074 | chr1_160332454_- | 0.00188596099952337 | 0.590500179020904 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| TCX | 0.00141730259030347 | 0.306101485931983 |
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RelatedDrugs for COPA |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for COPA |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| COPA | C0003864 | Arthritis | 1 | CTD_human |
| COPA | C0004364 | Autoimmune Diseases | 1 | CTD_human |
| COPA | C0162323 | Polyarthritis | 1 | CTD_human |
| COPA | C0206061 | Pneumonia, Interstitial | 1 | CTD_human |
| COPA | C0206062 | Lung Diseases, Interstitial | 1 | CTD_human |
| COPA | C4225334 | AUTOIMMUNE INTERSTITIAL LUNG, JOINT, AND KIDNEY DISEASE | 1 | CTD_human;ORPHANET;UNIPROT |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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