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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for CYB5D2

check button Gene summary
Gene informationGene symbol

CYB5D2

Gene ID

124936

Gene namecytochrome b5 domain containing 2
Synonyms-
Cytomap

17p13.2

Type of geneprotein-coding
Descriptionneuferricincytochrome b5 domain-containing protein 2
Modification date20200313
UniProtAcc

Q8WUJ1,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for CYB5D2

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_620201(4143249, +), ADediting_620202(4143272, +), ADediting_620203(4143331, +), ADediting_620204(4143341, +), ADediting_620205(4143369, +), ADediting_620206(4143372, +), ADediting_620207(4143379, +), ADediting_620208(4143405, +), ADediting_620209(4143406, +), ADediting_620210(4143411, +), ADediting_620211(4143415, +), ADediting_620212(4143432, +), ADediting_620213(4143446, +), ADediting_620214(4143447, +), ADediting_620215(4143454, +), ADediting_620216(4143467, +), ADediting_620217(4143471, +), ADediting_620218(4143517, +), ADediting_620219(4144805, +), ADediting_620220(4144813, +), ADediting_620221(4144867, +), ADediting_620222(4144926, +), ADediting_620223(4144928, +), ADediting_620224(4144968, +), ADediting_620225(4144971, +), ADediting_620226(4144993, +), ADediting_620227(4145047, +), ADediting_620228(4145048, +), ADediting_620229(4145060, +), ADediting_620230(4145062, +), ADediting_620231(4145078, +), ADediting_620232(4145822, +), ADediting_620233(4145838, +), ADediting_620234(4145860, +), ADediting_620235(4145873, +), ADediting_620236(4145879, +), ADediting_620237(4145893, +), ADediting_620238(4145899, +), ADediting_620239(4145902, +), ADediting_620240(4145903, +), ADediting_620241(4145911, +), ADediting_620242(4145924, +), ADediting_620243(4145925, +), ADediting_620244(4145938, +), ADediting_620245(4145948, +), ADediting_620246(4145960, +), ADediting_620247(4145982, +), ADediting_620248(4146008, +), ADediting_620249(4146021, +), ADediting_620250(4146034, +), ADediting_620251(4146159, +), ADediting_620252(4146227, +), ADediting_620253(4146233, +), ADediting_620254(4146422, +), ADediting_620255(4146439, +), ADediting_620256(4146454, +), ADediting_620257(4146520, +), ADediting_620258(4146530, +), ADediting_620259(4146597, +), ADediting_620260(4146642, +), ADediting_620261(4146664, +), ADediting_620262(4147150, +), ADediting_620263(4147180, +), ADediting_620264(4147192, +), ADediting_620265(4147196, +), ADediting_620266(4147203, +), ADediting_620267(4147220, +), ADediting_620268(4147221, +), ADediting_620269(4147228, +), ADediting_620270(4147654, +), ADediting_620271(4147655, +), ADediting_620272(4147658, +), ADediting_620273(4147733, +), ADediting_620274(4147746, +), ADediting_620275(4148297, +), ADediting_620276(4148331, +), ADediting_620277(4148370, +), ADediting_620278(4148410, +), ADediting_620279(4148584, +), ADediting_620280(4148605, +), ADediting_620281(4148606, +), ADediting_620282(4148677, +), ADediting_620283(4148681, +), ADediting_620284(4148703, +), ADediting_620285(4148756, +), ADediting_620286(4148984, +), ADediting_620287(4148992, +), ADediting_620288(4149527, +), ADediting_620289(4149543, +), ADediting_620290(4149547, +), ADediting_620291(4149656, +), ADediting_620292(4149688, +), ADediting_620293(4149721, +), ADediting_620294(4149727, +), ADediting_620295(4149731, +), ADediting_620296(4149751, +), ADediting_620297(4150724, +), ADediting_620298(4151436, +), ADediting_620299(4152871, +), ADediting_620300(4152877, +), ADediting_620301(4152895, +), ADediting_620302(4159131, +), ADediting_620303(4159145, +), ADediting_620304(4159147, +), ADediting_620305(4159151, +), ADediting_620306(4159186, +), ADediting_620307(4159189, +), ADediting_620308(4159215, +), ADediting_620309(4160610, +), ADediting_620310(4160641, +), ADediting_620311(4160646, +), ADediting_620312(4160655, +), ADediting_620313(4160658, +), ADediting_620314(4160660, +), ADediting_620315(4160665, +), ADediting_620316(4160709, +), ADediting_620317(4160721, +), ADediting_620318(4160731, +), ADediting_620319(4160737, +), ADediting_620320(4160741, +), ADediting_620321(4160744, +), ADediting_620322(4160757, +), ADediting_620323(4160765, +), ADediting_620324(4160773, +), ADediting_620325(4160799, +), ADediting_620326(4160812, +), ADediting_620327(4160825, +), ADediting_620328(4160828, +), ADediting_620329(4160837, +), ADediting_620330(4162132, +), ADediting_620331(4162134, +), ADediting_620332(4162135, +), ADediting_620333(4162140, +), ADediting_620334(4162156, +), ADediting_620335(4162157, +), ADediting_620336(4162176, +), ADediting_620337(4162198, +), ADediting_620338(4162208, +), ADediting_620339(4162210, +), ADediting_620340(4162218, +), ADediting_620341(4162229, +), ADediting_620342(4162232, +), ADediting_620343(4162233, +), ADediting_620344(4162234, +), ADediting_620345(4162235, +), ADediting_620346(4162239, +), ADediting_620347(4162240, +), ADediting_620348(4162241, +), ADediting_620349(4162242, +), ADediting_620350(4162246, +), ADediting_620351(4162262, +), ADediting_620352(4162266, +), ADediting_620353(4162272, +), ADediting_620354(4162282, +), ADediting_620355(4162306, +), ADediting_620356(4162313, +), ADediting_620357(4162316, +), ADediting_620358(4162318, +), ADediting_620359(4162326, +), ADediting_1546385(4143271, +), ADediting_1546386(4143486, +), ADediting_1546387(4144806, +), ADediting_1546388(4145928, +), ADediting_1546389(4146052, +),

Top

RNA editing positional annotations for CYB5D2 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_620201chr17_4143249_+UTR5
ADediting_620202chr17_4143272_+UTR5
ADediting_620203chr17_4143331_+UTR5
ADediting_620204chr17_4143341_+UTR5
ADediting_620205chr17_4143369_+UTR5
ADediting_620206chr17_4143372_+UTR5
ADediting_620207chr17_4143379_+UTR5
ADediting_620208chr17_4143405_+UTR5
ADediting_620209chr17_4143406_+UTR5
ADediting_620210chr17_4143411_+UTR5
ADediting_620211chr17_4143415_+UTR5
ADediting_620212chr17_4143432_+UTR5
ADediting_620213chr17_4143446_+UTR5
ADediting_620214chr17_4143447_+UTR5
ADediting_620215chr17_4143454_+UTR5
ADediting_620216chr17_4143467_+UTR5
ADediting_620217chr17_4143471_+UTR5
ADediting_620218chr17_4143517_+UTR5
ADediting_620219chr17_4144805_+intronic
ADediting_620220chr17_4144813_+intronic
ADediting_620221chr17_4144867_+intronic
ADediting_620222chr17_4144926_+intronic
ADediting_620223chr17_4144928_+intronic
ADediting_620224chr17_4144968_+intronic
ADediting_620225chr17_4144971_+intronic
ADediting_620226chr17_4144993_+intronic
ADediting_620227chr17_4145047_+intronic
ADediting_620228chr17_4145048_+intronic
ADediting_620229chr17_4145060_+intronic
ADediting_620230chr17_4145062_+intronic
ADediting_620231chr17_4145078_+intronic
ADediting_620232chr17_4145822_+intronic
ADediting_620233chr17_4145838_+intronic
ADediting_620234chr17_4145860_+intronic
ADediting_620235chr17_4145873_+intronic
ADediting_620236chr17_4145879_+intronic
ADediting_620237chr17_4145893_+intronic
ADediting_620238chr17_4145899_+intronic
ADediting_620239chr17_4145902_+intronic
ADediting_620240chr17_4145903_+intronic
ADediting_620241chr17_4145911_+intronic
ADediting_620242chr17_4145924_+intronic
ADediting_620243chr17_4145925_+intronic
ADediting_620244chr17_4145938_+intronic
ADediting_620245chr17_4145948_+intronic
ADediting_620246chr17_4145960_+intronic
ADediting_620247chr17_4145982_+intronic
ADediting_620248chr17_4146008_+intronic
ADediting_620249chr17_4146021_+intronic
ADediting_620250chr17_4146034_+intronic
ADediting_620251chr17_4146159_+intronic
ADediting_620252chr17_4146227_+intronic
ADediting_620253chr17_4146233_+intronic
ADediting_620254chr17_4146422_+intronic
ADediting_620255chr17_4146439_+intronic
ADediting_620256chr17_4146454_+intronic
ADediting_620257chr17_4146520_+intronic
ADediting_620258chr17_4146530_+intronic
ADediting_620259chr17_4146597_+intronic
ADediting_620260chr17_4146642_+intronic
ADediting_620261chr17_4146664_+intronic
ADediting_620262chr17_4147150_+intronic
ADediting_620263chr17_4147180_+intronic
ADediting_620264chr17_4147192_+intronic
ADediting_620265chr17_4147196_+intronic
ADediting_620266chr17_4147203_+intronic
ADediting_620267chr17_4147220_+intronic
ADediting_620268chr17_4147221_+intronic
ADediting_620269chr17_4147228_+intronic
ADediting_620270chr17_4147654_+intronic
ADediting_620271chr17_4147655_+intronic
ADediting_620272chr17_4147658_+intronic
ADediting_620273chr17_4147733_+intronic
ADediting_620274chr17_4147746_+intronic
ADediting_620275chr17_4148297_+intronic
ADediting_620276chr17_4148331_+intronic
ADediting_620277chr17_4148370_+intronic
ADediting_620278chr17_4148410_+intronic
ADediting_620279chr17_4148584_+intronic
ADediting_620280chr17_4148605_+intronic
ADediting_620281chr17_4148606_+intronic
ADediting_620282chr17_4148677_+intronic
ADediting_620283chr17_4148681_+intronic
ADediting_620284chr17_4148703_+intronic
ADediting_620285chr17_4148756_+intronic
ADediting_620286chr17_4148984_+intronic
ADediting_620287chr17_4148992_+intronic
ADediting_620288chr17_4149527_+intronic
ADediting_620289chr17_4149543_+intronic
ADediting_620290chr17_4149547_+intronic
ADediting_620291chr17_4149656_+intronic
ADediting_620292chr17_4149688_+intronic
ADediting_620293chr17_4149721_+intronic
ADediting_620294chr17_4149727_+intronic
ADediting_620295chr17_4149731_+intronic
ADediting_620296chr17_4149751_+intronic
ADediting_620297chr17_4150724_+intronic
ADediting_620298chr17_4151436_+intronic
ADediting_620299chr17_4152871_+intronic
ADediting_620300chr17_4152877_+intronic
ADediting_620301chr17_4152895_+intronic
ADediting_620302chr17_4159131_+intronic
ADediting_620303chr17_4159145_+intronic
ADediting_620304chr17_4159147_+intronic
ADediting_620305chr17_4159151_+intronic
ADediting_620306chr17_4159186_+intronic
ADediting_620307chr17_4159189_+intronic
ADediting_620308chr17_4159215_+intronic
ADediting_620309chr17_4160610_+intronic
ADediting_620310chr17_4160641_+intronic
ADediting_620311chr17_4160646_+intronic
ADediting_620312chr17_4160655_+intronic
ADediting_620313chr17_4160658_+intronic
ADediting_620314chr17_4160660_+intronic
ADediting_620315chr17_4160665_+intronic
ADediting_620316chr17_4160709_+intronic
ADediting_620317chr17_4160721_+intronic
ADediting_620318chr17_4160731_+intronic
ADediting_620319chr17_4160737_+intronic
ADediting_620320chr17_4160741_+intronic
ADediting_620321chr17_4160744_+intronic
ADediting_620322chr17_4160757_+intronic
ADediting_620323chr17_4160765_+intronic
ADediting_620324chr17_4160773_+intronic
ADediting_620325chr17_4160799_+intronic
ADediting_620326chr17_4160812_+intronic
ADediting_620327chr17_4160825_+intronic
ADediting_620328chr17_4160828_+intronic
ADediting_620329chr17_4160837_+intronic
ADediting_620330chr17_4162132_+intronic
ADediting_620331chr17_4162134_+intronic
ADediting_620332chr17_4162135_+intronic
ADediting_620333chr17_4162140_+intronic
ADediting_620334chr17_4162156_+intronic
ADediting_620335chr17_4162157_+intronic
ADediting_620336chr17_4162176_+intronic
ADediting_620337chr17_4162198_+intronic
ADediting_620338chr17_4162208_+intronic
ADediting_620339chr17_4162210_+intronic
ADediting_620340chr17_4162218_+intronic
ADediting_620341chr17_4162229_+intronic
ADediting_620342chr17_4162232_+intronic
ADediting_620343chr17_4162233_+intronic
ADediting_620344chr17_4162234_+intronic
ADediting_620345chr17_4162235_+intronic
ADediting_620346chr17_4162239_+intronic
ADediting_620347chr17_4162240_+intronic
ADediting_620348chr17_4162241_+intronic
ADediting_620349chr17_4162242_+intronic
ADediting_620350chr17_4162246_+intronic
ADediting_620351chr17_4162262_+intronic
ADediting_620352chr17_4162266_+intronic
ADediting_620353chr17_4162272_+intronic
ADediting_620354chr17_4162282_+intronic
ADediting_620355chr17_4162306_+intronic
ADediting_620356chr17_4162313_+intronic
ADediting_620357chr17_4162316_+intronic
ADediting_620358chr17_4162318_+intronic
ADediting_620359chr17_4162326_+intronic
ADediting_1546385chr17_4143271_+UTR5
ADediting_1546386chr17_4143486_+UTR5
ADediting_1546387chr17_4144806_+intronic
ADediting_1546388chr17_4145928_+intronic
ADediting_1546389chr17_4146052_+intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_620201chr17_4143249_+SINEAluName=AluSq
ADediting_620202chr17_4143272_+SINEAluName=AluSq
ADediting_620203chr17_4143331_+SINEAluName=AluSq
ADediting_620204chr17_4143341_+SINEAluName=AluSq
ADediting_620205chr17_4143369_+SINEAluName=AluSq
ADediting_620206chr17_4143372_+SINEAluName=AluSq
ADediting_620207chr17_4143379_+SINEAluName=AluSq
ADediting_620208chr17_4143405_+SINEAluName=AluSq
ADediting_620209chr17_4143406_+SINEAluName=AluSq
ADediting_620210chr17_4143411_+SINEAluName=AluSq
ADediting_620211chr17_4143415_+SINEAluName=AluSq
ADediting_620212chr17_4143432_+SINEAluName=AluSq
ADediting_620213chr17_4143446_+SINEAluName=AluSq
ADediting_620214chr17_4143447_+SINEAluName=AluSq
ADediting_620215chr17_4143454_+SINEAluName=AluSq
ADediting_620216chr17_4143467_+SINEAluName=AluSq
ADediting_620217chr17_4143471_+SINEAluName=AluSq
ADediting_620218chr17_4143517_+SINEAluName=AluSq
ADediting_620219chr17_4144805_+SINEAluName=AluY
ADediting_620220chr17_4144813_+SINEAluName=AluY
ADediting_620221chr17_4144867_+SINEAluName=AluY
ADediting_620222chr17_4144926_+SINEAluName=AluY
ADediting_620223chr17_4144928_+SINEAluName=AluY
ADediting_620224chr17_4144968_+SINEAluName=AluY
ADediting_620225chr17_4144971_+SINEAluName=AluY
ADediting_620226chr17_4144993_+SINEAluName=AluY
ADediting_620227chr17_4145047_+SINEAluName=AluY
ADediting_620228chr17_4145048_+SINEAluName=AluY
ADediting_620229chr17_4145060_+SINEAluName=AluY
ADediting_620230chr17_4145062_+SINEAluName=AluY
ADediting_620231chr17_4145078_+SINEAluName=AluY
ADediting_620232chr17_4145822_+SINEAluName=AluJb
ADediting_620233chr17_4145838_+SINEAluName=AluJb
ADediting_620234chr17_4145860_+SINEAluName=AluJb
ADediting_620235chr17_4145873_+SINEAluName=AluJb
ADediting_620236chr17_4145879_+SINEAluName=AluJb
ADediting_620237chr17_4145893_+SINEAluName=AluJb
ADediting_620238chr17_4145899_+SINEAluName=AluJb
ADediting_620239chr17_4145902_+SINEAluName=AluJb
ADediting_620240chr17_4145903_+SINEAluName=AluJb
ADediting_620241chr17_4145911_+SINEAluName=AluJb
ADediting_620242chr17_4145924_+SINEAluName=AluJb
ADediting_620243chr17_4145925_+SINEAluName=AluJb
ADediting_620244chr17_4145938_+SINEAluName=AluJb
ADediting_620245chr17_4145948_+SINEAluName=AluJb
ADediting_620246chr17_4145960_+SINEAluName=AluJb
ADediting_620247chr17_4145982_+SINEAluName=AluJb
ADediting_620248chr17_4146008_+SINEAluName=AluJb
ADediting_620249chr17_4146021_+SINEAluName=AluJb
ADediting_620250chr17_4146034_+SINEAluName=AluJb
ADediting_620251chr17_4146159_+SINEAluName=AluSz6
ADediting_620252chr17_4146227_+SINEAluName=AluSz6
ADediting_620253chr17_4146233_+SINEAluName=AluSz6
ADediting_620254chr17_4146422_+SINEAluName=AluYm1
ADediting_620255chr17_4146439_+SINEAluName=AluYm1
ADediting_620256chr17_4146454_+SINEAluName=AluYm1
ADediting_620257chr17_4146520_+SINEAluName=AluYm1
ADediting_620258chr17_4146530_+SINEAluName=AluYm1
ADediting_620259chr17_4146597_+SINEAluName=AluYm1
ADediting_620260chr17_4146642_+SINEAluName=AluYm1
ADediting_620261chr17_4146664_+SINEAluName=AluYm1
ADediting_620262chr17_4147150_+SINEAluName=AluSx4
ADediting_620263chr17_4147180_+SINEAluName=AluSx4
ADediting_620264chr17_4147192_+SINEAluName=AluSx4
ADediting_620265chr17_4147196_+SINEAluName=AluSx4
ADediting_620266chr17_4147203_+SINEAluName=AluSx4
ADediting_620267chr17_4147220_+SINEAluName=AluSx4
ADediting_620268chr17_4147221_+SINEAluName=AluSx4
ADediting_620269chr17_4147228_+SINEAluName=AluSx4
ADediting_620270chr17_4147654_+SINEAluName=AluSp
ADediting_620271chr17_4147655_+SINEAluName=AluSp
ADediting_620272chr17_4147658_+SINEAluName=AluSp
ADediting_620273chr17_4147733_+SINEAluName=AluSp
ADediting_620274chr17_4147746_+SINEAluName=AluSp
ADediting_620275chr17_4148297_+SINEAluName=AluSx1
ADediting_620276chr17_4148331_+SINEAluName=AluSx1
ADediting_620277chr17_4148370_+SINEAluName=AluSx1
ADediting_620278chr17_4148410_+SINEAluName=AluSx1
ADediting_620279chr17_4148584_+SINEAluName=AluSx
ADediting_620280chr17_4148605_+SINEAluName=AluSx
ADediting_620281chr17_4148606_+SINEAluName=AluSx
ADediting_620282chr17_4148677_+SINEAluName=AluSx
ADediting_620283chr17_4148681_+SINEAluName=AluSx
ADediting_620284chr17_4148703_+SINEAluName=AluSx
ADediting_620285chr17_4148756_+SINEAluName=AluSx
ADediting_620286chr17_4148984_+SINEAluName=AluJo
ADediting_620287chr17_4148992_+SINEAluName=AluJo
ADediting_620288chr17_4149527_+SINEAluName=AluSx1
ADediting_620289chr17_4149543_+SINEAluName=AluSx1
ADediting_620290chr17_4149547_+SINEAluName=AluSx1
ADediting_620291chr17_4149656_+SINEAluName=AluSx1
ADediting_620292chr17_4149688_+SINEAluName=AluSx1
ADediting_620293chr17_4149721_+SINEAluName=AluSx1
ADediting_620294chr17_4149727_+SINEAluName=AluSx1
ADediting_620295chr17_4149731_+SINEAluName=AluSx1
ADediting_620296chr17_4149751_+SINEAluName=AluSx1
ADediting_620297chr17_4150724_+SINEAluName=AluSz
ADediting_620298chr17_4151436_+SINEAluName=AluSx1
ADediting_620299chr17_4152871_+SINEAluName=AluSz
ADediting_620300chr17_4152877_+SINEAluName=AluSz
ADediting_620301chr17_4152895_+SINEAluName=AluSz
ADediting_620302chr17_4159131_+SINEAluName=AluSg
ADediting_620303chr17_4159145_+SINEAluName=AluSg
ADediting_620304chr17_4159147_+SINEAluName=AluSg
ADediting_620305chr17_4159151_+SINEAluName=AluSg
ADediting_620306chr17_4159186_+SINEAluName=AluSg
ADediting_620307chr17_4159189_+SINEAluName=AluSg
ADediting_620308chr17_4159215_+SINEAluName=AluSg
ADediting_620309chr17_4160610_+SINEAluName=AluJb
ADediting_620310chr17_4160641_+SINEAluName=AluJb
ADediting_620311chr17_4160646_+SINEAluName=AluJb
ADediting_620312chr17_4160655_+SINEAluName=AluJb
ADediting_620313chr17_4160658_+SINEAluName=AluJb
ADediting_620314chr17_4160660_+SINEAluName=AluJb
ADediting_620315chr17_4160665_+SINEAluName=AluJb
ADediting_620316chr17_4160709_+SINEAluName=AluJb
ADediting_620317chr17_4160721_+SINEAluName=AluJb
ADediting_620318chr17_4160731_+SINEAluName=AluJb
ADediting_620319chr17_4160737_+SINEAluName=AluJb
ADediting_620320chr17_4160741_+SINEAluName=AluJb
ADediting_620321chr17_4160744_+SINEAluName=AluJb
ADediting_620322chr17_4160757_+SINEAluName=AluJb
ADediting_620323chr17_4160765_+SINEAluName=AluJb
ADediting_620324chr17_4160773_+SINEAluName=AluJb
ADediting_620325chr17_4160799_+SINEAluName=AluJb
ADediting_620326chr17_4160812_+SINEAluName=AluJb
ADediting_620327chr17_4160825_+SINEAluName=AluJb
ADediting_620328chr17_4160828_+SINEAluName=AluJb
ADediting_620329chr17_4160837_+SINEAluName=AluJb
ADediting_620330chr17_4162132_+SINEAluName=AluSz
ADediting_620331chr17_4162134_+SINEAluName=AluSz
ADediting_620332chr17_4162135_+SINEAluName=AluSz
ADediting_620333chr17_4162140_+SINEAluName=AluSz
ADediting_620334chr17_4162156_+SINEAluName=AluSz
ADediting_620335chr17_4162157_+SINEAluName=AluSz
ADediting_620336chr17_4162176_+SINEAluName=AluSz
ADediting_620337chr17_4162198_+SINEAluName=AluSz
ADediting_620338chr17_4162208_+SINEAluName=AluSz
ADediting_620339chr17_4162210_+SINEAluName=AluSz
ADediting_620340chr17_4162218_+SINEAluName=AluSz
ADediting_620341chr17_4162229_+SINEAluName=AluSz
ADediting_620342chr17_4162232_+SINEAluName=AluSz
ADediting_620343chr17_4162233_+SINEAluName=AluSz
ADediting_620344chr17_4162234_+SINEAluName=AluSz
ADediting_620345chr17_4162235_+SINEAluName=AluSz
ADediting_620346chr17_4162239_+SINEAluName=AluSz
ADediting_620347chr17_4162240_+SINEAluName=AluSz
ADediting_620348chr17_4162241_+SINEAluName=AluSz
ADediting_620349chr17_4162242_+SINEAluName=AluSz
ADediting_620350chr17_4162246_+SINEAluName=AluSz
ADediting_620351chr17_4162262_+SINEAluName=AluSz
ADediting_620352chr17_4162266_+SINEAluName=AluSz
ADediting_620353chr17_4162272_+SINEAluName=AluSz
ADediting_620354chr17_4162282_+SINEAluName=AluSz
ADediting_620355chr17_4162306_+SINEAluName=AluSz
ADediting_620356chr17_4162313_+SINEAluName=AluSz
ADediting_620357chr17_4162316_+SINEAluName=AluSz
ADediting_620358chr17_4162318_+SINEAluName=AluSz
ADediting_620359chr17_4162326_+SINEAluName=AluSz
ADediting_1546385chr17_4143271_+SINEAluName=AluSq
ADediting_1546386chr17_4143486_+SINEAluName=AluSq
ADediting_1546387chr17_4144806_+SINEAluName=AluY
ADediting_1546388chr17_4145928_+SINEAluName=AluJb
ADediting_1546389chr17_4146052_+SINEAluName=AluJb

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RNA A-to-I editing events in the alternative splicing sites for CYB5D2

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
A5SSADediting_620204chr17_4143341_+4143340:41433485ss2eAACGTGGTG-9.84AGCGTGGTG-15.27
A5SSADediting_620204chr17_4143341_+4143340:41433485ss2eAACGTGGTG-9.84AGCGTGGTG-15.27
ESADediting_620247chr17_4145982_+4145964:41459863ss2iAATTTTTGTATTTTTTGTAGAGA6.53AATTTTTGTATTTTTTGTGGAGA-1.43
ESADediting_620247chr17_4145982_+4145964:41459863ss2iAATTTTTGTATTTTTTGTAGAGA6.53AATTTTTGTATTTTTTGTGGAGA-1.43
ESADediting_620247chr17_4145982_+4145964:41459863ss2iAATTTTTGTATTTTTTGTAGAGA6.53AATTTTTGTATTTTTTGTGGAGA-1.43
ESADediting_620247chr17_4145982_+4145964:41459863ss2iAATTTTTGTATTTTTTGTAGAGA6.53AATTTTTGTATTTTTTGTGGAGA-1.43

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CYB5D2

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
Soverview
Soverview

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Soverview
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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for CYB5D2

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for CYB5D2


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1556067chr19_40282625_-ENSG00000167740.9ENST00000301391.7CYB5D2-201hsa-miR-641chr17415751641575227mer-m841574994157523148-18.18
ADediting_1556067chr19_40282625_-ENSG00000167740.9ENST00000575251.5CYB5D2-203hsa-miR-641chr17415751641575227mer-m841574994157523148-18.18
ADediting_1596844chr1_162342605_+ENSG00000167740.9ENST00000301391.7CYB5D2-201hsa-miR-556-3pchr17415744341574508mer-1a41574294157450143-8.35
ADediting_1596844chr1_162342605_+ENSG00000167740.9ENST00000575251.5CYB5D2-203hsa-miR-556-3pchr17415744341574508mer-1a41574294157450143-8.35
ADediting_843620chr2_207754818_+ENSG00000167740.9ENST00000301391.7CYB5D2-201hsa-miR-4775chr17415757441575807mer-m841575564157581146-11.01

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_496066chr15_66496985_-ENSG00000167740.9ENST00000301391.7CYB5D2-201hsa-miR-4512chr17415713541571417mer-m841571224157142146-16.07
ADediting_496066chr15_66496985_-ENSG00000167740.9ENST00000575251.5CYB5D2-203hsa-miR-4512chr17415713541571417mer-m841571224157142146-16.07
ADediting_527135chr16_24203190_+ENSG00000167740.9ENST00000301391.7CYB5D2-201hsa-miR-1273h-3pchr17415760741576137mer-m841575924157614150-15.93

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CYB5D2

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000577075.6protein_codingSoverviewSoverview
ENST00000575251.5protein_codingSoverviewSoverview
ENST00000301391.7protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_620201ENST00000577075.6chr17_4143249_+82-257.10-255.80-259.30
ADediting_1546385ENST00000577075.6chr17_4143271_+104-258.50-255.80-259.30
ADediting_620202ENST00000577075.6chr17_4143272_+105-256.90-255.80-259.30
ADediting_620201ENST00000575251.5chr17_4143249_+39-572.10-572.20-589.50
ADediting_1546385ENST00000575251.5chr17_4143271_+61-572.30-572.20-589.50
ADediting_620202ENST00000575251.5chr17_4143272_+62-572.20-572.20-589.50
ADediting_620203ENST00000575251.5chr17_4143331_+121-573.00-572.20-589.50
ADediting_620204ENST00000575251.5chr17_4143341_+131-572.60-572.20-589.50
ADediting_620205ENST00000575251.5chr17_4143369_+159-572.20-572.20-589.50
ADediting_620206ENST00000575251.5chr17_4143372_+162-572.20-572.20-589.50
ADediting_620207ENST00000575251.5chr17_4143379_+169-575.70-572.20-589.50
ADediting_620208ENST00000575251.5chr17_4143405_+195-578.60-572.20-589.50
ADediting_620209ENST00000575251.5chr17_4143406_+196-572.50-572.20-589.50
ADediting_620210ENST00000575251.5chr17_4143411_+201-572.90-572.20-589.50
ADediting_620211ENST00000575251.5chr17_4143415_+205-572.50-572.20-589.50
ADediting_620212ENST00000575251.5chr17_4143432_+222-571.50-572.20-589.50
ADediting_620213ENST00000575251.5chr17_4143446_+236-572.20-572.20-589.50
ADediting_620214ENST00000575251.5chr17_4143447_+237-572.60-572.20-589.50
ADediting_620215ENST00000575251.5chr17_4143454_+244-572.20-572.20-589.50
ADediting_620216ENST00000575251.5chr17_4143467_+257-571.50-572.20-589.50
ADediting_620217ENST00000575251.5chr17_4143471_+261-572.30-572.20-589.50
ADediting_1546386ENST00000575251.5chr17_4143486_+276-571.50-572.20-589.50
ADediting_620218ENST00000575251.5chr17_4143517_+307-572.20-572.20-589.50
ADediting_1546385ENST00000301391.7chr17_4143271_+16-712.10-711.90-731.10
ADediting_620202ENST00000301391.7chr17_4143272_+17-713.70-711.90-731.10
ADediting_620203ENST00000301391.7chr17_4143331_+76-712.70-711.90-731.10
ADediting_620204ENST00000301391.7chr17_4143341_+86-712.30-711.90-731.10
ADediting_620205ENST00000301391.7chr17_4143369_+114-712.90-711.90-731.10
ADediting_620206ENST00000301391.7chr17_4143372_+117-714.60-711.90-731.10
ADediting_620207ENST00000301391.7chr17_4143379_+124-711.90-711.90-731.10
ADediting_620208ENST00000301391.7chr17_4143405_+150-711.50-711.90-731.10
ADediting_620209ENST00000301391.7chr17_4143406_+151-712.70-711.90-731.10
ADediting_620210ENST00000301391.7chr17_4143411_+156-714.90-711.90-731.10
ADediting_620211ENST00000301391.7chr17_4143415_+160-712.50-711.90-731.10
ADediting_620212ENST00000301391.7chr17_4143432_+177-713.60-711.90-731.10
ADediting_620213ENST00000301391.7chr17_4143446_+191-711.90-711.90-731.10
ADediting_620214ENST00000301391.7chr17_4143447_+192-713.00-711.90-731.10
ADediting_620215ENST00000301391.7chr17_4143454_+199-712.30-711.90-731.10
ADediting_620216ENST00000301391.7chr17_4143467_+212-713.00-711.90-731.10
ADediting_620217ENST00000301391.7chr17_4143471_+216-715.40-711.90-731.10
ADediting_1546386ENST00000301391.7chr17_4143486_+231-711.20-711.90-731.10
ADediting_620218ENST00000301391.7chr17_4143517_+262-711.90-711.90-731.10

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for CYB5D2

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_620203chr17_4143331_+8.58955314719788e-060.3544344870790333.60966759695939e-070.4012356833612940.08181713222032950.142555807039683
DLPFCADediting_620226chr17_4144993_+0.409528303729649-0.04700516775812260.0876433082363831-0.09716861555185034.13206564363948e-090.326043495988706
DLPFCADediting_620232chr17_4145822_+0.08637297665945010.09755851526821120.7268464275185990.0199187421662573.9785009512758e-110.363677904104626
DLPFCADediting_620237chr17_4145893_+0.1467106039419440.08261817524216220.8329706308705460.01202607665477848.33391268372145e-100.339596194406831
DLPFCADediting_620241chr17_4145911_+0.09121155254168480.09609716572099790.9748680185719460.001796533432294813.7782821069539e-130.397049117970076
DLPFCADediting_620242chr17_4145924_+0.652611724016140.0256655289855080.218685023573017-0.07005828807545994.8488098322077e-130.395354173340183
DLPFCADediting_620250chr17_4146034_+0.08116370288343630.09920732844473050.3827536889825490.04974388306941724.02574034536835e-090.326269558820466
DLPFCADediting_620252chr17_4146227_+0.4143378912437140.04652463690599640.48100593584508-0.04016956878483142.17932529556478e-170.45681915047625
DLPFCADediting_620270chr17_4147654_+0.1344879419104020.08519277953003120.855862554864362-0.01035822214310983.6929339859438e-100.346242065693592
DLPFCADediting_620272chr17_4147658_+0.004408588079246890.1613094567760510.2962731404198410.0595090922842164.47776910983171e-100.3446826705665
DLPFCADediting_620277chr17_4148370_+0.07507061162343250.1012481356699320.8429992050680460.01129424054196224.36296697054062e-100.344893348584023
DLPFCADediting_620288chr17_4149527_+0.02430313971112230.127913025314080.5562441714080840.03354665101009483.10040988699427e-180.46746895132217
DLPFCADediting_620289chr17_4149543_+0.496133030472230.03879690250188150.277436831745039-0.06187690859849633.78453396397776e-220.512360718782507
DLPFCADediting_620290chr17_4149547_+0.9981547334112-0.0001318853617605630.0683586132806537-0.103658465111964.30836826718021e-170.453007603885451
DLPFCADediting_620291chr17_4149656_+0.478867945334474-0.04036544082815340.0852111961659593-0.09791915356641329.50681448782726e-110.356987124235906
DLPFCADediting_620296chr17_4149751_+0.2934279218086880.05986014840988920.764720020167296-0.01706614271476462.37737186524372e-090.330797911495956
CERADediting_620334chr17_4162156_+0.1042713748497330.1331615843067761.01585657569548e-050.3517407743068810.06653860225814250.150214411479388
CERADediting_620338chr17_4162208_+0.02466508919774290.1834101470091342.50231908832231e-060.3735203548880370.01166102283800530.205456823297321
TCXADediting_620350chr17_4162246_+0.1347284312651490.1226889519919461.14001110262552e-050.3498750543176680.0228394343442782-0.185776841709478
CERADediting_620351chr17_4162262_+0.04721935178861690.1623014946886132.18843320162408e-050.3390934865145980.006396123899557450.221715111492928

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC4.47172673290426e-370.6396922637847185.11900668252031e-240.5316644478248661.06536995057983e-410.6697028613196
AC1.65222852592351e-800.8760205299998581.07384762906687e-530.7859164435193284.08179954732964e-170.498578671647743
PCC2.87731201776919e-400.7795986705486381.13844765913542e-380.7695858298911230.0005232854313181090.24865384482002
CER5.50053791961155e-180.6303072388574126.02318265712694e-070.394149185533480.003848463857091110.234652662707732
TCX2.37415259473768e-240.7104925546969791.832205009402e-060.3781571198823484.56936508031362e-050.326421756307782
FP4.56932184110457e-240.6647957502927819.94382257280141e-280.7018841078164353.51702757049365e-050.304824994450267
IFG3.41998444985243e-050.7301898512255976.83147640876426e-050.7107978497156520.6459112222557020.0966210790097933
PG1.78827172425791e-100.4459252903894341.52669720296063e-130.5070362844733510.3567766740328020.0679493860069271
STG1.21293002936566e-210.8208086177941622.05467034981003e-110.650855265099490.02060326862085610.252285817105247

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Relation with AD stages for CYB5D2

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_620203chr17_4143331_+0.0004828202573353910.330206943219393
CERADediting_620340chr17_4162218_+0.0003904317741144810.335229817403535
CERADediting_620351chr17_4162262_+0.0001883922201906330.351847492825565

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.

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RelatedDrugs for CYB5D2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for CYB5D2

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource
CYB5D2C1527249Colorectal Cancer1UNIPROT