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	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited versus non-edited samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with AD stages
	Related drugs with this gene
	Related diseases with this gene

Gene summary for MRPL52

Gene summary

Gene information	Gene symbol	MRPL52
	Gene ID	122704
	Gene name	mitochondrial ribosomal protein L52
	Synonyms	-
	Cytomap	14q11.2
	Type of gene	protein-coding
	Description	39S ribosomal protein L52, mitochondrialL52mtMRP-L52mitochondrial large ribosomal subunit protein mL52
	Modification date	20200313
	UniProtAcc	Q86TS9,
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for MRPL52

RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA editing frequencies across three data sets.

The number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA A-to-I editing events in AD.

ADediting_420241(22831152, +), ADediting_420242(22831187, +), ADediting_420243(22831212, +), ADediting_420244(22831213, +), ADediting_420245(22831216, +), ADediting_420246(22831225, +), ADediting_420247(22831230, +), ADediting_420248(22831242, +), ADediting_420249(22831252, +), ADediting_420250(22831254, +), ADediting_420251(22831298, +), ADediting_420252(22831307, +), ADediting_420253(22831328, +), ADediting_420254(22831347, +), ADediting_420255(22831366, +), ADediting_420256(22831376, +), ADediting_420257(22831913, +), ADediting_420258(22831926, +), ADediting_420259(22831927, +), ADediting_420260(22831932, +), ADediting_420261(22831949, +), ADediting_420262(22831951, +), ADediting_420263(22832360, +), ADediting_420264(22832370, +), ADediting_420265(22832396, +), ADediting_420266(22832415, +), ADediting_420267(22832421, +), ADediting_420268(22832440, +), ADediting_420269(22832458, +), ADediting_420270(22832470, +), ADediting_420271(22832475, +), ADediting_420272(22832480, +), ADediting_420273(22832482, +), ADediting_420274(22832506, +), ADediting_420275(22832507, +), ADediting_420276(22832525, +), ADediting_420277(22832531, +), ADediting_420278(22832547, +), ADediting_420279(22832562, +), ADediting_420280(22832571, +), ADediting_420281(22832592, +), ADediting_420282(22832602, +), ADediting_420283(22832614, +), ADediting_420284(22832732, +), ADediting_420285(22832752, +), ADediting_420286(22832758, +), ADediting_420287(22832759, +), ADediting_420288(22832781, +), ADediting_420289(22832785, +), ADediting_420290(22832800, +), ADediting_420291(22832834, +), ADediting_420292(22832924, +), ADediting_420293(22832925, +), ADediting_420294(22832960, +), ADediting_420295(22832968, +), ADediting_420296(22832969, +), ADediting_420297(22832991, +), ADediting_420298(22832992, +), ADediting_420299(22833000, +), ADediting_420300(22833013, +), ADediting_420301(22833016, +), ADediting_420302(22833017, +), ADediting_420303(22833018, +), ADediting_420304(22833020, +), ADediting_420305(22833022, +), ADediting_420306(22833031, +), ADediting_420307(22833035, +), ADediting_420308(22833057, +), ADediting_420309(22833084, +), ADediting_420310(22833098, +), ADediting_420311(22833099, +), ADediting_420312(22833119, +), ADediting_420313(22833159, +), ADediting_420314(22833675, +), ADediting_420315(22833681, +), ADediting_420316(22833721, +), ADediting_420317(22833722, +), ADediting_420318(22833733, +), ADediting_420319(22833739, +), ADediting_420320(22833751, +), ADediting_420321(22833761, +), ADediting_420322(22833779, +), ADediting_420323(22833783, +), ADediting_420324(22833787, +), ADediting_420325(22833795, +), ADediting_420326(22833801, +), ADediting_420327(22833810, +), ADediting_420328(22833873, +), ADediting_420329(22833883, +), ADediting_420330(22833895, +), ADediting_420331(22833911, +), ADediting_420332(22834579, +), ADediting_420333(22834580, +), ADediting_420334(22834585, +), ADediting_420335(22834610, +), ADediting_420336(22834618, +), ADediting_420337(22834687, +), ADediting_420338(22834691, +), ADediting_420339(22834701, +), ADediting_420340(22834727, +), ADediting_420341(22834728, +), ADediting_420342(22834741, +), ADediting_420343(22834750, +), ADediting_420344(22834754, +), ADediting_420345(22834760, +), ADediting_420346(22834767, +), ADediting_420347(22834768, +), ADediting_420348(22834793, +), ADediting_420349(22834797, +), ADediting_420350(22834798, +), ADediting_1536349(22831156, +), ADediting_1536350(22831192, +), ADediting_1536351(22831375, +), ADediting_1536352(22831918, +), ADediting_1536353(22831919, +), ADediting_1536354(22832384, +), ADediting_1536355(22832451, +), ADediting_1536356(22832775, +), ADediting_1536357(22832858, +), ADediting_1536358(22833067, +), ADediting_1536359(22833110, +), ADediting_1536360(22833123, +), ADediting_1536361(22833138, +), ADediting_1536362(22833156, +), ADediting_1536363(22833668, +), ADediting_1536364(22833788, +), ADediting_1536365(22833804, +),

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RNA editing positional annotations for MRPL52 using Annovar

Protein coding RNA editing(s).

ADeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

ADeditome ID	Position	Variant type
ADediting_420241	chr14_22831152_+	intronic
ADediting_420242	chr14_22831187_+	intronic
ADediting_420243	chr14_22831212_+	intronic
ADediting_420244	chr14_22831213_+	intronic
ADediting_420245	chr14_22831216_+	intronic
ADediting_420246	chr14_22831225_+	intronic
ADediting_420247	chr14_22831230_+	intronic
ADediting_420248	chr14_22831242_+	intronic
ADediting_420249	chr14_22831252_+	intronic
ADediting_420250	chr14_22831254_+	intronic
ADediting_420251	chr14_22831298_+	intronic
ADediting_420252	chr14_22831307_+	intronic
ADediting_420253	chr14_22831328_+	intronic
ADediting_420254	chr14_22831347_+	intronic
ADediting_420255	chr14_22831366_+	intronic
ADediting_420256	chr14_22831376_+	intronic
ADediting_420257	chr14_22831913_+	intronic
ADediting_420258	chr14_22831926_+	intronic
ADediting_420259	chr14_22831927_+	intronic
ADediting_420260	chr14_22831932_+	intronic
ADediting_420261	chr14_22831949_+	intronic
ADediting_420262	chr14_22831951_+	intronic
ADediting_420263	chr14_22832360_+	intronic
ADediting_420264	chr14_22832370_+	intronic
ADediting_420265	chr14_22832396_+	intronic
ADediting_420266	chr14_22832415_+	intronic
ADediting_420267	chr14_22832421_+	intronic
ADediting_420268	chr14_22832440_+	intronic
ADediting_420269	chr14_22832458_+	intronic
ADediting_420270	chr14_22832470_+	intronic
ADediting_420271	chr14_22832475_+	intronic
ADediting_420272	chr14_22832480_+	intronic
ADediting_420273	chr14_22832482_+	intronic
ADediting_420274	chr14_22832506_+	intronic
ADediting_420275	chr14_22832507_+	intronic
ADediting_420276	chr14_22832525_+	intronic
ADediting_420277	chr14_22832531_+	intronic
ADediting_420278	chr14_22832547_+	intronic
ADediting_420279	chr14_22832562_+	intronic
ADediting_420280	chr14_22832571_+	intronic
ADediting_420281	chr14_22832592_+	intronic
ADediting_420282	chr14_22832602_+	intronic
ADediting_420283	chr14_22832614_+	intronic
ADediting_420284	chr14_22832732_+	intronic
ADediting_420285	chr14_22832752_+	intronic
ADediting_420286	chr14_22832758_+	intronic
ADediting_420287	chr14_22832759_+	intronic
ADediting_420288	chr14_22832781_+	intronic
ADediting_420289	chr14_22832785_+	intronic
ADediting_420290	chr14_22832800_+	intronic
ADediting_420291	chr14_22832834_+	intronic
ADediting_420292	chr14_22832924_+	intronic
ADediting_420293	chr14_22832925_+	intronic
ADediting_420294	chr14_22832960_+	intronic
ADediting_420295	chr14_22832968_+	intronic
ADediting_420296	chr14_22832969_+	intronic
ADediting_420297	chr14_22832991_+	intronic
ADediting_420298	chr14_22832992_+	intronic
ADediting_420299	chr14_22833000_+	intronic
ADediting_420300	chr14_22833013_+	intronic
ADediting_420301	chr14_22833016_+	intronic
ADediting_420302	chr14_22833017_+	intronic
ADediting_420303	chr14_22833018_+	intronic
ADediting_420304	chr14_22833020_+	intronic
ADediting_420305	chr14_22833022_+	intronic
ADediting_420306	chr14_22833031_+	intronic
ADediting_420307	chr14_22833035_+	intronic
ADediting_420308	chr14_22833057_+	intronic
ADediting_420309	chr14_22833084_+	intronic
ADediting_420310	chr14_22833098_+	intronic
ADediting_420311	chr14_22833099_+	intronic
ADediting_420312	chr14_22833119_+	intronic
ADediting_420313	chr14_22833159_+	intronic
ADediting_420314	chr14_22833675_+	intronic
ADediting_420315	chr14_22833681_+	intronic
ADediting_420316	chr14_22833721_+	intronic
ADediting_420317	chr14_22833722_+	intronic
ADediting_420318	chr14_22833733_+	intronic
ADediting_420319	chr14_22833739_+	intronic
ADediting_420320	chr14_22833751_+	intronic
ADediting_420321	chr14_22833761_+	intronic
ADediting_420322	chr14_22833779_+	intronic
ADediting_420323	chr14_22833783_+	intronic
ADediting_420324	chr14_22833787_+	intronic
ADediting_420325	chr14_22833795_+	intronic
ADediting_420326	chr14_22833801_+	intronic
ADediting_420327	chr14_22833810_+	intronic
ADediting_420328	chr14_22833873_+	intronic
ADediting_420329	chr14_22833883_+	intronic
ADediting_420330	chr14_22833895_+	intronic
ADediting_420331	chr14_22833911_+	intronic
ADediting_420332	chr14_22834579_+	UTR3
ADediting_420333	chr14_22834580_+	UTR3
ADediting_420334	chr14_22834585_+	UTR3
ADediting_420335	chr14_22834610_+	UTR3
ADediting_420336	chr14_22834618_+	UTR3
ADediting_420337	chr14_22834687_+	UTR3
ADediting_420338	chr14_22834691_+	UTR3
ADediting_420339	chr14_22834701_+	UTR3
ADediting_420340	chr14_22834727_+	UTR3
ADediting_420341	chr14_22834728_+	UTR3
ADediting_420342	chr14_22834741_+	UTR3
ADediting_420343	chr14_22834750_+	UTR3
ADediting_420344	chr14_22834754_+	UTR3
ADediting_420345	chr14_22834760_+	UTR3
ADediting_420346	chr14_22834767_+	UTR3
ADediting_420347	chr14_22834768_+	UTR3
ADediting_420348	chr14_22834793_+	UTR3
ADediting_420349	chr14_22834797_+	UTR3
ADediting_420350	chr14_22834798_+	UTR3
ADediting_1536349	chr14_22831156_+	intronic
ADediting_1536350	chr14_22831192_+	intronic
ADediting_1536351	chr14_22831375_+	intronic
ADediting_1536352	chr14_22831918_+	intronic
ADediting_1536353	chr14_22831919_+	intronic
ADediting_1536354	chr14_22832384_+	intronic
ADediting_1536355	chr14_22832451_+	intronic
ADediting_1536356	chr14_22832775_+	intronic
ADediting_1536357	chr14_22832858_+	intronic
ADediting_1536358	chr14_22833067_+	intronic
ADediting_1536359	chr14_22833110_+	intronic
ADediting_1536360	chr14_22833123_+	intronic
ADediting_1536361	chr14_22833138_+	intronic
ADediting_1536362	chr14_22833156_+	intronic
ADediting_1536363	chr14_22833668_+	intronic
ADediting_1536364	chr14_22833788_+	intronic
ADediting_1536365	chr14_22833804_+	intronic

Repat-regional RNA editing(s).

ADeditome ID	Position	Repeat family	Repeat sub family	Repeat name
ADediting_420241	chr14_22831152_+	SINE	Alu	Name=AluJo
ADediting_420242	chr14_22831187_+	SINE	Alu	Name=AluJo
ADediting_420243	chr14_22831212_+	SINE	Alu	Name=AluJo
ADediting_420244	chr14_22831213_+	SINE	Alu	Name=AluJo
ADediting_420245	chr14_22831216_+	SINE	Alu	Name=AluJo
ADediting_420246	chr14_22831225_+	SINE	Alu	Name=AluJo
ADediting_420247	chr14_22831230_+	SINE	Alu	Name=AluJo
ADediting_420248	chr14_22831242_+	SINE	Alu	Name=AluJo
ADediting_420249	chr14_22831252_+	SINE	Alu	Name=AluJo
ADediting_420250	chr14_22831254_+	SINE	Alu	Name=AluJo
ADediting_420251	chr14_22831298_+	SINE	Alu	Name=AluJo
ADediting_420252	chr14_22831307_+	SINE	Alu	Name=AluJo
ADediting_420253	chr14_22831328_+	SINE	Alu	Name=AluJo
ADediting_420254	chr14_22831347_+	SINE	Alu	Name=AluJo
ADediting_420255	chr14_22831366_+	SINE	Alu	Name=AluJo
ADediting_420256	chr14_22831376_+	SINE	Alu	Name=AluJo
ADediting_420257	chr14_22831913_+	SINE	Alu	Name=AluSx3
ADediting_420258	chr14_22831926_+	SINE	Alu	Name=AluSx3
ADediting_420259	chr14_22831927_+	SINE	Alu	Name=AluSx3
ADediting_420260	chr14_22831932_+	SINE	Alu	Name=AluSx3
ADediting_420261	chr14_22831949_+	SINE	Alu	Name=AluSx3
ADediting_420262	chr14_22831951_+	SINE	Alu	Name=AluSx3
ADediting_420263	chr14_22832360_+	SINE	Alu	Name=AluY
ADediting_420264	chr14_22832370_+	SINE	Alu	Name=AluY
ADediting_420265	chr14_22832396_+	SINE	Alu	Name=AluY
ADediting_420266	chr14_22832415_+	SINE	Alu	Name=AluY
ADediting_420267	chr14_22832421_+	SINE	Alu	Name=AluY
ADediting_420268	chr14_22832440_+	SINE	Alu	Name=AluY
ADediting_420269	chr14_22832458_+	SINE	Alu	Name=AluY
ADediting_420270	chr14_22832470_+	SINE	Alu	Name=AluY
ADediting_420271	chr14_22832475_+	SINE	Alu	Name=AluY
ADediting_420272	chr14_22832480_+	SINE	Alu	Name=AluY
ADediting_420273	chr14_22832482_+	SINE	Alu	Name=AluY
ADediting_420274	chr14_22832506_+	SINE	Alu	Name=AluY
ADediting_420275	chr14_22832507_+	SINE	Alu	Name=AluY
ADediting_420276	chr14_22832525_+	SINE	Alu	Name=AluY
ADediting_420277	chr14_22832531_+	SINE	Alu	Name=AluY
ADediting_420278	chr14_22832547_+	SINE	Alu	Name=AluY
ADediting_420279	chr14_22832562_+	SINE	Alu	Name=AluY
ADediting_420280	chr14_22832571_+	SINE	Alu	Name=AluY
ADediting_420281	chr14_22832592_+	SINE	Alu	Name=AluY
ADediting_420282	chr14_22832602_+	SINE	Alu	Name=AluY
ADediting_420283	chr14_22832614_+	SINE	Alu	Name=AluY
ADediting_420284	chr14_22832732_+	SINE	Alu	Name=AluSp
ADediting_420285	chr14_22832752_+	SINE	Alu	Name=AluSp
ADediting_420286	chr14_22832758_+	SINE	Alu	Name=AluSp
ADediting_420287	chr14_22832759_+	SINE	Alu	Name=AluSp
ADediting_420288	chr14_22832781_+	SINE	Alu	Name=AluSp
ADediting_420289	chr14_22832785_+	SINE	Alu	Name=AluSp
ADediting_420290	chr14_22832800_+	SINE	Alu	Name=AluSp
ADediting_420291	chr14_22832834_+	SINE	Alu	Name=AluSp
ADediting_420292	chr14_22832924_+	SINE	Alu	Name=AluSc
ADediting_420293	chr14_22832925_+	SINE	Alu	Name=AluSc
ADediting_420294	chr14_22832960_+	SINE	Alu	Name=AluSc
ADediting_420295	chr14_22832968_+	SINE	Alu	Name=AluSc
ADediting_420296	chr14_22832969_+	SINE	Alu	Name=AluSc
ADediting_420297	chr14_22832991_+	SINE	Alu	Name=AluSc
ADediting_420298	chr14_22832992_+	SINE	Alu	Name=AluSc
ADediting_420299	chr14_22833000_+	SINE	Alu	Name=AluSc
ADediting_420300	chr14_22833013_+	SINE	Alu	Name=AluSc
ADediting_420301	chr14_22833016_+	SINE	Alu	Name=AluSc
ADediting_420302	chr14_22833017_+	SINE	Alu	Name=AluSc
ADediting_420303	chr14_22833018_+	SINE	Alu	Name=AluSc
ADediting_420304	chr14_22833020_+	SINE	Alu	Name=AluSc
ADediting_420305	chr14_22833022_+	SINE	Alu	Name=AluSc
ADediting_420306	chr14_22833031_+	SINE	Alu	Name=AluSc
ADediting_420307	chr14_22833035_+	SINE	Alu	Name=AluSc
ADediting_420308	chr14_22833057_+	SINE	Alu	Name=AluSc
ADediting_420309	chr14_22833084_+	SINE	Alu	Name=AluSc
ADediting_420310	chr14_22833098_+	SINE	Alu	Name=AluSc
ADediting_420311	chr14_22833099_+	SINE	Alu	Name=AluSc
ADediting_420312	chr14_22833119_+	SINE	Alu	Name=AluSc
ADediting_420313	chr14_22833159_+	SINE	Alu	Name=AluSc
ADediting_420314	chr14_22833675_+	SINE	Alu	Name=AluSp
ADediting_420315	chr14_22833681_+	SINE	Alu	Name=AluSp
ADediting_420316	chr14_22833721_+	SINE	Alu	Name=AluSp
ADediting_420317	chr14_22833722_+	SINE	Alu	Name=AluSp
ADediting_420318	chr14_22833733_+	SINE	Alu	Name=AluSp
ADediting_420319	chr14_22833739_+	SINE	Alu	Name=AluSp
ADediting_420320	chr14_22833751_+	SINE	Alu	Name=AluSp
ADediting_420321	chr14_22833761_+	SINE	Alu	Name=AluSp
ADediting_420322	chr14_22833779_+	SINE	Alu	Name=AluSp
ADediting_420323	chr14_22833783_+	SINE	Alu	Name=AluSp
ADediting_420324	chr14_22833787_+	SINE	Alu	Name=AluSp
ADediting_420325	chr14_22833795_+	SINE	Alu	Name=AluSp
ADediting_420326	chr14_22833801_+	SINE	Alu	Name=AluSp
ADediting_420327	chr14_22833810_+	SINE	Alu	Name=AluSp
ADediting_420328	chr14_22833873_+	SINE	Alu	Name=AluSp
ADediting_420329	chr14_22833883_+	SINE	Alu	Name=AluSp
ADediting_420330	chr14_22833895_+	SINE	Alu	Name=AluSp
ADediting_420331	chr14_22833911_+	SINE	Alu	Name=AluSp
ADediting_420332	chr14_22834579_+	SINE	Alu	Name=AluSg
ADediting_420333	chr14_22834580_+	SINE	Alu	Name=AluSg
ADediting_420334	chr14_22834585_+	SINE	Alu	Name=AluSg
ADediting_420335	chr14_22834610_+	SINE	Alu	Name=AluSg
ADediting_420336	chr14_22834618_+	SINE	Alu	Name=AluSg
ADediting_420337	chr14_22834687_+	SINE	Alu	Name=AluSg
ADediting_420338	chr14_22834691_+	SINE	Alu	Name=AluSg
ADediting_420339	chr14_22834701_+	SINE	Alu	Name=AluSg
ADediting_420340	chr14_22834727_+	SINE	Alu	Name=AluSg
ADediting_420341	chr14_22834728_+	SINE	Alu	Name=AluSg
ADediting_420342	chr14_22834741_+	SINE	Alu	Name=AluSg
ADediting_420343	chr14_22834750_+	SINE	Alu	Name=AluSg
ADediting_420344	chr14_22834754_+	SINE	Alu	Name=AluSg
ADediting_420345	chr14_22834760_+	SINE	Alu	Name=AluSg
ADediting_420346	chr14_22834767_+	SINE	Alu	Name=AluSg
ADediting_420347	chr14_22834768_+	SINE	Alu	Name=AluSg
ADediting_420348	chr14_22834793_+	SINE	Alu	Name=AluSg
ADediting_420349	chr14_22834797_+	SINE	Alu	Name=AluSg
ADediting_420350	chr14_22834798_+	SINE	Alu	Name=AluSg
ADediting_1536349	chr14_22831156_+	SINE	Alu	Name=AluJo
ADediting_1536350	chr14_22831192_+	SINE	Alu	Name=AluJo
ADediting_1536351	chr14_22831375_+	SINE	Alu	Name=AluJo
ADediting_1536352	chr14_22831918_+	SINE	Alu	Name=AluSx3
ADediting_1536353	chr14_22831919_+	SINE	Alu	Name=AluSx3
ADediting_1536354	chr14_22832384_+	SINE	Alu	Name=AluY
ADediting_1536355	chr14_22832451_+	SINE	Alu	Name=AluY
ADediting_1536356	chr14_22832775_+	SINE	Alu	Name=AluSp
ADediting_1536357	chr14_22832858_+	SINE	Alu	Name=AluSp
ADediting_1536358	chr14_22833067_+	SINE	Alu	Name=AluSc
ADediting_1536359	chr14_22833110_+	SINE	Alu	Name=AluSc
ADediting_1536360	chr14_22833123_+	SINE	Alu	Name=AluSc
ADediting_1536361	chr14_22833138_+	SINE	Alu	Name=AluSc
ADediting_1536362	chr14_22833156_+	SINE	Alu	Name=AluSc
ADediting_1536363	chr14_22833668_+	SINE	Alu	Name=AluSp
ADediting_1536364	chr14_22833788_+	SINE	Alu	Name=AluSp
ADediting_1536365	chr14_22833804_+	SINE	Alu	Name=AluSp

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RNA A-to-I editing events in the alternative splicing sites for MRPL52

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

ADeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MRPL52

Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A.

Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window.

- Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window.

ADeditome ID

Chr

Positoing

Skipped exon

ENSG

ENSTs