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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for SFXN2

check button Gene summary
Gene informationGene symbol

SFXN2

Gene ID

118980

Gene namesideroflexin 2
SynonymsSLC56A2
Cytomap

10q24.32

Type of geneprotein-coding
Descriptionsideroflexin-2
Modification date20200313
UniProtAcc

Q96NB2,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
SFXN2

GO:1990542

mitochondrial transmembrane transport

30442778


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RNA A-to-I events for SFXN2

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_158625(102730967, +), ADediting_158626(102731156, +), ADediting_158627(102731503, +), ADediting_158628(102733957, +), ADediting_158629(102733981, +), ADediting_158630(102736031, +), ADediting_158631(102736319, +), ADediting_158632(102736335, +), ADediting_158633(102736351, +), ADediting_158634(102736356, +), ADediting_158635(102736357, +), ADediting_158636(102736479, +), ADediting_158637(102736485, +), ADediting_158638(102736534, +), ADediting_158639(102736546, +), ADediting_158640(102736556, +), ADediting_158641(102736591, +), ADediting_158642(102736597, +), ADediting_158643(102736600, +), ADediting_158644(102736667, +), ADediting_158645(102736677, +), ADediting_158646(102736689, +), ADediting_158647(102736730, +), ADediting_158648(102736733, +), ADediting_158649(102736772, +), ADediting_158650(102736774, +), ADediting_158651(102736785, +), ADediting_158652(102736803, +), ADediting_158653(102736811, +), ADediting_158654(102736812, +), ADediting_158655(102736813, +), ADediting_158656(102736816, +), ADediting_158657(102736825, +), ADediting_158658(102736935, +), ADediting_158659(102736954, +), ADediting_158660(102736969, +), ADediting_158661(102736971, +), ADediting_158662(102736977, +), ADediting_158663(102736978, +), ADediting_158664(102736979, +), ADediting_158665(102737033, +), ADediting_158666(102737034, +), ADediting_158667(102737039, +), ADediting_158668(102737043, +), ADediting_158669(102737051, +), ADediting_158670(102737057, +), ADediting_158671(102737083, +), ADediting_158672(102737111, +), ADediting_158673(102737137, +), ADediting_158674(102738080, +), ADediting_158675(102738094, +), ADediting_158676(102738109, +), ADediting_158677(102738110, +), ADediting_158678(102738111, +), ADediting_158679(102738123, +), ADediting_158680(102738124, +), ADediting_158681(102738125, +), ADediting_158682(102738126, +), ADediting_158683(102738130, +), ADediting_158684(102738137, +), ADediting_158685(102738139, +), ADediting_158686(102738169, +), ADediting_158687(102738186, +), ADediting_158688(102738200, +), ADediting_158689(102738348, +), ADediting_158690(102738414, +), ADediting_158691(102738549, +), ADediting_158692(102739656, +), ADediting_158693(102739657, +), ADediting_158694(102739683, +), ADediting_158695(102739692, +), ADediting_158696(102739697, +), ADediting_158697(102739711, +), ADediting_158698(102739736, +), ADediting_158699(102739792, +), ADediting_158700(102739793, +), ADediting_158701(102739825, +), ADediting_158702(102739828, +), ADediting_158703(102739833, +), ADediting_158704(102739834, +), ADediting_158705(102739862, +), ADediting_158706(102739863, +), ADediting_158707(102740268, +), ADediting_158708(102740270, +), ADediting_158709(102740305, +), ADediting_158710(102740311, +), ADediting_158711(102740333, +), ADediting_158712(102740346, +), ADediting_158713(102740347, +), ADediting_158714(102740350, +), ADediting_158715(102740351, +), ADediting_158716(102740364, +), ADediting_158717(102740411, +), ADediting_158718(102740444, +), ADediting_158719(102740456, +), ADediting_158720(102740457, +), ADediting_158721(102740461, +), ADediting_158722(102740474, +), ADediting_158723(102740483, +), ADediting_158724(102740484, +), ADediting_158725(102740492, +), ADediting_158726(102740496, +), ADediting_158727(102741421, +), ADediting_158728(102741422, +), ADediting_158729(102741423, +), ADediting_158730(102741424, +), ADediting_158731(102741461, +), ADediting_158732(102741464, +), ADediting_158733(102741470, +), ADediting_158734(102741472, +), ADediting_158735(102741475, +), ADediting_158736(102741492, +), ADediting_158737(102741515, +), ADediting_158738(102741544, +), ADediting_158739(102741550, +), ADediting_158740(102741605, +), ADediting_158741(102741640, +), ADediting_158742(102741643, +), ADediting_1522219(102716670, +), ADediting_1522220(102716694, +), ADediting_1522221(102716695, +), ADediting_1522222(102716698, +), ADediting_1522223(102734027, +), ADediting_1522224(102736747, +), ADediting_1522225(102738074, +), ADediting_1522226(102738098, +), ADediting_1522227(102738105, +), ADediting_1522228(102738108, +), ADediting_1522229(102738526, +), ADediting_1522230(102738531, +), ADediting_1522231(102741353, +), ADediting_1522232(102741354, +), ADediting_1522233(102741518, +), ADediting_1522234(102741577, +),

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RNA editing positional annotations for SFXN2 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_158625chr10_102730967_+intronic
ADediting_158626chr10_102731156_+intronic
ADediting_158627chr10_102731503_+intronic
ADediting_158628chr10_102733957_+intronic
ADediting_158629chr10_102733981_+intronic
ADediting_158630chr10_102736031_+intronic
ADediting_158631chr10_102736319_+intronic
ADediting_158632chr10_102736335_+intronic
ADediting_158633chr10_102736351_+intronic
ADediting_158634chr10_102736356_+intronic
ADediting_158635chr10_102736357_+intronic
ADediting_158636chr10_102736479_+intronic
ADediting_158637chr10_102736485_+intronic
ADediting_158638chr10_102736534_+intronic
ADediting_158639chr10_102736546_+intronic
ADediting_158640chr10_102736556_+intronic
ADediting_158641chr10_102736591_+intronic
ADediting_158642chr10_102736597_+intronic
ADediting_158643chr10_102736600_+intronic
ADediting_158644chr10_102736667_+intronic
ADediting_158645chr10_102736677_+intronic
ADediting_158646chr10_102736689_+intronic
ADediting_158647chr10_102736730_+intronic
ADediting_158648chr10_102736733_+intronic
ADediting_158649chr10_102736772_+intronic
ADediting_158650chr10_102736774_+intronic
ADediting_158651chr10_102736785_+intronic
ADediting_158652chr10_102736803_+intronic
ADediting_158653chr10_102736811_+intronic
ADediting_158654chr10_102736812_+intronic
ADediting_158655chr10_102736813_+intronic
ADediting_158656chr10_102736816_+intronic
ADediting_158657chr10_102736825_+intronic
ADediting_158658chr10_102736935_+intronic
ADediting_158659chr10_102736954_+intronic
ADediting_158660chr10_102736969_+intronic
ADediting_158661chr10_102736971_+intronic
ADediting_158662chr10_102736977_+intronic
ADediting_158663chr10_102736978_+intronic
ADediting_158664chr10_102736979_+intronic
ADediting_158665chr10_102737033_+intronic
ADediting_158666chr10_102737034_+intronic
ADediting_158667chr10_102737039_+intronic
ADediting_158668chr10_102737043_+intronic
ADediting_158669chr10_102737051_+intronic
ADediting_158670chr10_102737057_+intronic
ADediting_158671chr10_102737083_+intronic
ADediting_158672chr10_102737111_+intronic
ADediting_158673chr10_102737137_+intronic
ADediting_158674chr10_102738080_+UTR3
ADediting_158675chr10_102738094_+UTR3
ADediting_158676chr10_102738109_+UTR3
ADediting_158677chr10_102738110_+UTR3
ADediting_158678chr10_102738111_+UTR3
ADediting_158679chr10_102738123_+UTR3
ADediting_158680chr10_102738124_+UTR3
ADediting_158681chr10_102738125_+UTR3
ADediting_158682chr10_102738126_+UTR3
ADediting_158683chr10_102738130_+UTR3
ADediting_158684chr10_102738137_+UTR3
ADediting_158685chr10_102738139_+UTR3
ADediting_158686chr10_102738169_+UTR3
ADediting_158687chr10_102738186_+UTR3
ADediting_158688chr10_102738200_+UTR3
ADediting_158689chr10_102738348_+UTR3
ADediting_158690chr10_102738414_+UTR3
ADediting_158691chr10_102738549_+UTR3
ADediting_158692chr10_102739656_+UTR3
ADediting_158693chr10_102739657_+UTR3
ADediting_158694chr10_102739683_+UTR3
ADediting_158695chr10_102739692_+UTR3
ADediting_158696chr10_102739697_+UTR3
ADediting_158697chr10_102739711_+UTR3
ADediting_158698chr10_102739736_+UTR3
ADediting_158699chr10_102739792_+UTR3
ADediting_158700chr10_102739793_+UTR3
ADediting_158701chr10_102739825_+UTR3
ADediting_158702chr10_102739828_+UTR3
ADediting_158703chr10_102739833_+UTR3
ADediting_158704chr10_102739834_+UTR3
ADediting_158705chr10_102739862_+UTR3
ADediting_158706chr10_102739863_+UTR3
ADediting_158707chr10_102740268_+UTR3
ADediting_158708chr10_102740270_+UTR3
ADediting_158709chr10_102740305_+UTR3
ADediting_158710chr10_102740311_+UTR3
ADediting_158711chr10_102740333_+UTR3
ADediting_158712chr10_102740346_+UTR3
ADediting_158713chr10_102740347_+UTR3
ADediting_158714chr10_102740350_+UTR3
ADediting_158715chr10_102740351_+UTR3
ADediting_158716chr10_102740364_+UTR3
ADediting_158717chr10_102740411_+UTR3
ADediting_158718chr10_102740444_+UTR3
ADediting_158719chr10_102740456_+UTR3
ADediting_158720chr10_102740457_+UTR3
ADediting_158721chr10_102740461_+UTR3
ADediting_158722chr10_102740474_+UTR3
ADediting_158723chr10_102740483_+UTR3
ADediting_158724chr10_102740484_+UTR3
ADediting_158725chr10_102740492_+UTR3
ADediting_158726chr10_102740496_+UTR3
ADediting_158727chr10_102741421_+UTR3
ADediting_158728chr10_102741422_+UTR3
ADediting_158729chr10_102741423_+UTR3
ADediting_158730chr10_102741424_+UTR3
ADediting_158731chr10_102741461_+UTR3
ADediting_158732chr10_102741464_+UTR3
ADediting_158733chr10_102741470_+UTR3
ADediting_158734chr10_102741472_+UTR3
ADediting_158735chr10_102741475_+UTR3
ADediting_158736chr10_102741492_+UTR3
ADediting_158737chr10_102741515_+UTR3
ADediting_158738chr10_102741544_+UTR3
ADediting_158739chr10_102741550_+UTR3
ADediting_158740chr10_102741605_+UTR3
ADediting_158741chr10_102741640_+UTR3
ADediting_158742chr10_102741643_+UTR3
ADediting_1522219chr10_102716670_+UTR5
ADediting_1522220chr10_102716694_+UTR5
ADediting_1522221chr10_102716695_+UTR5
ADediting_1522222chr10_102716698_+UTR5
ADediting_1522223chr10_102734027_+intronic
ADediting_1522224chr10_102736747_+intronic
ADediting_1522225chr10_102738074_+UTR3
ADediting_1522226chr10_102738098_+UTR3
ADediting_1522227chr10_102738105_+UTR3
ADediting_1522228chr10_102738108_+UTR3
ADediting_1522229chr10_102738526_+UTR3
ADediting_1522230chr10_102738531_+UTR3
ADediting_1522231chr10_102741353_+UTR3
ADediting_1522232chr10_102741354_+UTR3
ADediting_1522233chr10_102741518_+UTR3
ADediting_1522234chr10_102741577_+UTR3

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_158625chr10_102730967_+SINEAluName=AluY
ADediting_158626chr10_102731156_+SINEAluName=AluSz6
ADediting_158627chr10_102731503_+SINEMIRName=MIRb
ADediting_158628chr10_102733957_+SINEAluName=AluSz
ADediting_158629chr10_102733981_+SINEAluName=AluSz
ADediting_158631chr10_102736319_+SINEAluName=AluSq
ADediting_158632chr10_102736335_+SINEAluName=AluSq
ADediting_158633chr10_102736351_+SINEAluName=AluSq
ADediting_158634chr10_102736356_+SINEAluName=AluSq
ADediting_158635chr10_102736357_+SINEAluName=AluSq
ADediting_158636chr10_102736479_+SINEAluName=AluSc5
ADediting_158637chr10_102736485_+SINEAluName=AluSc5
ADediting_158638chr10_102736534_+SINEAluName=AluSc5
ADediting_158639chr10_102736546_+SINEAluName=AluSc5
ADediting_158640chr10_102736556_+SINEAluName=AluSc5
ADediting_158641chr10_102736591_+SINEAluName=AluSc5
ADediting_158642chr10_102736597_+SINEAluName=AluSc5
ADediting_158643chr10_102736600_+SINEAluName=AluSc5
ADediting_158644chr10_102736667_+SINEAluName=AluSc5
ADediting_158645chr10_102736677_+SINEAluName=AluSc5
ADediting_158646chr10_102736689_+SINEAluName=AluSc5
ADediting_158647chr10_102736730_+SINEAluName=AluSq
ADediting_158648chr10_102736733_+SINEAluName=AluSq
ADediting_158649chr10_102736772_+SINEAluName=AluSq
ADediting_158650chr10_102736774_+SINEAluName=AluSq
ADediting_158651chr10_102736785_+SINEAluName=AluSq
ADediting_158652chr10_102736803_+SINEAluName=AluSq
ADediting_158653chr10_102736811_+SINEAluName=AluSq
ADediting_158654chr10_102736812_+SINEAluName=AluSq
ADediting_158655chr10_102736813_+SINEAluName=AluSq
ADediting_158656chr10_102736816_+SINEAluName=AluSq
ADediting_158657chr10_102736825_+SINEAluName=AluSq
ADediting_158658chr10_102736935_+SINEAluName=AluSp
ADediting_158659chr10_102736954_+SINEAluName=AluSp
ADediting_158660chr10_102736969_+SINEAluName=AluSp
ADediting_158661chr10_102736971_+SINEAluName=AluSp
ADediting_158662chr10_102736977_+SINEAluName=AluSp
ADediting_158663chr10_102736978_+SINEAluName=AluSp
ADediting_158664chr10_102736979_+SINEAluName=AluSp
ADediting_158665chr10_102737033_+SINEAluName=AluSp
ADediting_158666chr10_102737034_+SINEAluName=AluSp
ADediting_158667chr10_102737039_+SINEAluName=AluSp
ADediting_158668chr10_102737043_+SINEAluName=AluSp
ADediting_158669chr10_102737051_+SINEAluName=AluSp
ADediting_158670chr10_102737057_+SINEAluName=AluSp
ADediting_158671chr10_102737083_+SINEAluName=AluSp
ADediting_158672chr10_102737111_+SINEAluName=AluSp
ADediting_158673chr10_102737137_+SINEAluName=AluSp
ADediting_158689chr10_102738348_+SINEAluName=AluSx1
ADediting_158690chr10_102738414_+SINEAluName=AluSx1
ADediting_158691chr10_102738549_+SINEAluName=AluSx1
ADediting_158692chr10_102739656_+SINEAluName=AluSx
ADediting_158693chr10_102739657_+SINEAluName=AluSx
ADediting_158694chr10_102739683_+SINEAluName=AluSx
ADediting_158695chr10_102739692_+SINEAluName=AluSx
ADediting_158696chr10_102739697_+SINEAluName=AluSx
ADediting_158697chr10_102739711_+SINEAluName=AluSx
ADediting_158698chr10_102739736_+SINEAluName=AluSx
ADediting_158699chr10_102739792_+SINEAluName=AluSx
ADediting_158700chr10_102739793_+SINEAluName=AluSx
ADediting_158701chr10_102739825_+SINEAluName=AluSx
ADediting_158702chr10_102739828_+SINEAluName=AluSx
ADediting_158703chr10_102739833_+SINEAluName=AluSx
ADediting_158704chr10_102739834_+SINEAluName=AluSx
ADediting_158705chr10_102739862_+SINEAluName=AluSx
ADediting_158706chr10_102739863_+SINEAluName=AluSx
ADediting_158707chr10_102740268_+SINEAluName=AluJb
ADediting_158708chr10_102740270_+SINEAluName=AluJb
ADediting_158709chr10_102740305_+SINEAluName=AluJb
ADediting_158710chr10_102740311_+SINEAluName=AluJb
ADediting_158711chr10_102740333_+SINEAluName=AluJb
ADediting_158712chr10_102740346_+SINEAluName=AluJb
ADediting_158713chr10_102740347_+SINEAluName=AluJb
ADediting_158714chr10_102740350_+SINEAluName=AluJb
ADediting_158715chr10_102740351_+SINEAluName=AluJb
ADediting_158716chr10_102740364_+SINEAluName=AluJb
ADediting_158717chr10_102740411_+SINEAluName=AluJb
ADediting_158718chr10_102740444_+SINEAluName=AluJb
ADediting_158719chr10_102740456_+SINEAluName=AluJb
ADediting_158720chr10_102740457_+SINEAluName=AluJb
ADediting_158721chr10_102740461_+SINEAluName=AluJb
ADediting_158722chr10_102740474_+SINEAluName=AluJb
ADediting_158723chr10_102740483_+SINEAluName=AluJb
ADediting_158724chr10_102740484_+SINEAluName=AluJb
ADediting_158725chr10_102740492_+SINEAluName=AluJb
ADediting_158726chr10_102740496_+SINEAluName=AluJb
ADediting_158738chr10_102741544_+SINEAluName=AluJb
ADediting_158739chr10_102741550_+SINEAluName=AluJb
ADediting_158740chr10_102741605_+SINEAluName=AluJb
ADediting_158741chr10_102741640_+SINEAluName=AluJb
ADediting_158742chr10_102741643_+SINEAluName=AluJb
ADediting_1522219chr10_102716670_+SINEAluName=AluSp
ADediting_1522220chr10_102716694_+SINEAluName=AluSp
ADediting_1522221chr10_102716695_+SINEAluName=AluSp
ADediting_1522222chr10_102716698_+SINEAluName=AluSp
ADediting_1522223chr10_102734027_+SINEAluName=AluSz
ADediting_1522224chr10_102736747_+SINEAluName=AluSq
ADediting_1522229chr10_102738526_+SINEAluName=AluSx1
ADediting_1522230chr10_102738531_+SINEAluName=AluSx1
ADediting_1522231chr10_102741353_+SINEAluName=AluJb
ADediting_1522232chr10_102741354_+SINEAluName=AluJb
ADediting_1522234chr10_102741577_+SINEAluName=AluJb

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RNA A-to-I editing events in the alternative splicing sites for SFXN2

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SFXN2

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs