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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for ARAP1

check button Gene summary
Gene informationGene symbol

ARAP1

Gene ID

116985

Gene nameArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
SynonymsCENTD2
Cytomap

11q13.4

Type of geneprotein-coding
Descriptionarf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containing protein 1centaurin-delta-2cnt-d2
Modification date20200313
UniProtAcc

Q96P48,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
ARAP1

GO:0043547

positive regulation of GTPase activity

11804590


Top

RNA A-to-I events for ARAP1

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_277986(72715168, -), ADediting_277987(72715643, -), ADediting_277988(72715647, -), ADediting_277989(72715673, -), ADediting_277990(72715679, -), ADediting_277991(72715685, -), ADediting_277992(72715692, -), ADediting_277993(72715717, -), ADediting_277994(72715751, -), ADediting_277995(72715752, -), ADediting_277996(72715754, -), ADediting_277997(72715762, -), ADediting_277998(72715790, -), ADediting_277999(72732977, -), ADediting_278000(72734259, -), ADediting_278001(72735119, -), ADediting_278002(72735145, -), ADediting_278003(72735366, -), ADediting_278004(72735367, -), ADediting_278005(72735452, -), ADediting_278006(72735484, -), ADediting_278007(72735513, -), ADediting_278008(72735557, -), ADediting_278009(72735558, -), ADediting_278010(72735582, -), ADediting_278011(72745681, -), ADediting_278012(72745836, -), ADediting_278013(72749627, -), ADediting_278014(72749694, -), ADediting_278015(72749702, -), ADediting_278016(72749782, -), ADediting_278017(72749813, -), ADediting_278018(72755396, -), ADediting_278019(72755400, -), ADediting_278020(72755408, -), ADediting_278021(72755413, -), ADediting_278022(72755426, -), ADediting_278023(72755427, -), ADediting_278024(72755448, -), ADediting_278025(72755449, -), ADediting_278026(72755504, -), ADediting_278027(72755512, -), ADediting_278028(72755514, -), ADediting_278029(72755529, -), ADediting_278030(72755530, -), ADediting_278031(72755557, -), ADediting_278032(72755592, -), ADediting_278033(72755606, -), ADediting_278034(72756978, -), ADediting_278035(72757032, -), ADediting_278036(72757033, -), ADediting_278037(72757061, -), ADediting_278038(72757140, -), ADediting_278039(72759978, -), ADediting_278040(72759996, -), ADediting_278041(72760067, -), ADediting_278042(72760082, -), ADediting_278043(72760085, -), ADediting_278044(72760091, -), ADediting_278045(72760096, -), ADediting_278046(72760097, -), ADediting_278047(72760104, -), ADediting_278048(72760129, -), ADediting_278049(72760312, -), ADediting_278050(72760316, -), ADediting_278051(72760351, -), ADediting_278052(72760364, -), ADediting_278053(72760391, -), ADediting_278054(72760401, -), ADediting_278055(72760429, -), ADediting_278056(72760460, -), ADediting_278057(72760472, -), ADediting_278058(72761494, -), ADediting_278059(72761500, -), ADediting_278060(72761512, -), ADediting_278061(72761514, -), ADediting_278062(72761522, -), ADediting_278063(72761539, -), ADediting_278064(72761540, -), ADediting_278065(72761545, -), ADediting_278066(72761565, -), ADediting_278067(72761601, -), ADediting_278068(72761645, -), ADediting_278069(72761663, -), ADediting_278070(72761669, -), ADediting_278071(72761676, -), ADediting_278072(72761688, -), ADediting_278073(72761718, -), ADediting_278074(72761740, -), ADediting_278075(72761742, -), ADediting_278076(72761743, -), ADediting_278077(72761968, -), ADediting_278078(72761994, -), ADediting_278079(72762015, -), ADediting_278080(72762028, -), ADediting_278081(72762031, -), ADediting_278082(72762034, -), ADediting_278083(72762035, -), ADediting_278084(72762037, -), ADediting_278085(72762041, -), ADediting_278086(72762066, -), ADediting_278087(72762086, -), ADediting_278088(72762090, -), ADediting_278089(72762099, -), ADediting_278090(72762104, -), ADediting_278091(72762127, -), ADediting_278092(72762153, -), ADediting_278093(72762158, -), ADediting_278094(72762176, -), ADediting_278095(72762198, -), ADediting_278096(72762205, -), ADediting_278097(72765011, -), ADediting_278098(72765017, -), ADediting_278099(72765051, -), ADediting_278100(72765080, -), ADediting_278101(72765154, -), ADediting_278102(72770382, -), ADediting_278103(72771446, -), ADediting_278104(72773294, -), ADediting_278105(72777123, -), ADediting_278106(72777831, -), ADediting_278107(72779374, -), ADediting_278108(72779400, -), ADediting_278109(72779407, -), ADediting_278110(72779412, -), ADediting_278111(72779420, -), ADediting_278112(72779426, -), ADediting_278113(72779429, -), ADediting_278114(72779443, -), ADediting_278115(72779448, -), ADediting_278116(72779452, -), ADediting_278117(72779512, -), ADediting_278118(72779519, -), ADediting_278119(72779536, -), ADediting_278120(72779547, -), ADediting_278121(72779574, -), ADediting_278122(72791442, -), ADediting_278123(72791591, -), ADediting_278124(72791595, -), ADediting_278125(72792188, -), ADediting_278126(72792258, -), ADediting_278127(72792259, -), ADediting_1528623(72732733, -), ADediting_1528624(72755383, -), ADediting_1528625(72755416, -), ADediting_1528626(72755464, -), ADediting_1528627(72755475, -), ADediting_1528628(72755481, -), ADediting_1528629(72755489, -), ADediting_1528630(72755506, -), ADediting_1528631(72756902, -), ADediting_1528632(72757082, -), ADediting_1528633(72760375, -), ADediting_1528634(72760431, -), ADediting_1528635(72760478, -), ADediting_1528636(72762139, -), ADediting_1528637(72765714, -), ADediting_1528638(72770316, -), ADediting_1528639(72770371, -), ADediting_1528640(72770411, -), ADediting_1528641(72770419, -), ADediting_1528642(72773308, -), ADediting_1528643(72779444, -), ADediting_1528644(72779480, -),

Top

RNA editing positional annotations for ARAP1 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_277986chr11_72715168_-intronic
ADediting_277987chr11_72715643_-intronic
ADediting_277988chr11_72715647_-intronic
ADediting_277989chr11_72715673_-intronic
ADediting_277990chr11_72715679_-intronic
ADediting_277991chr11_72715685_-intronic
ADediting_277992chr11_72715692_-intronic
ADediting_277993chr11_72715717_-intronic
ADediting_277994chr11_72715751_-intronic
ADediting_277995chr11_72715752_-intronic
ADediting_277996chr11_72715754_-intronic
ADediting_277997chr11_72715762_-intronic
ADediting_277998chr11_72715790_-intronic
ADediting_277999chr11_72732977_-intronic
ADediting_278000chr11_72734259_-intronic
ADediting_278001chr11_72735119_-intronic
ADediting_278002chr11_72735145_-intronic
ADediting_278003chr11_72735366_-intronic
ADediting_278004chr11_72735367_-intronic
ADediting_278005chr11_72735452_-intronic
ADediting_278006chr11_72735484_-intronic
ADediting_278007chr11_72735513_-intronic
ADediting_278008chr11_72735557_-intronic
ADediting_278009chr11_72735558_-intronic
ADediting_278010chr11_72735582_-intronic
ADediting_278011chr11_72745681_-intronic
ADediting_278012chr11_72745836_-intronic
ADediting_278013chr11_72749627_-intronic
ADediting_278014chr11_72749694_-intronic
ADediting_278015chr11_72749702_-intronic
ADediting_278016chr11_72749782_-intronic
ADediting_278017chr11_72749813_-intronic
ADediting_278018chr11_72755396_-UTR3
ADediting_278019chr11_72755400_-UTR3
ADediting_278020chr11_72755408_-UTR3
ADediting_278021chr11_72755413_-UTR3
ADediting_278022chr11_72755426_-UTR3
ADediting_278023chr11_72755427_-UTR3
ADediting_278024chr11_72755448_-UTR3
ADediting_278025chr11_72755449_-UTR3
ADediting_278026chr11_72755504_-UTR3
ADediting_278027chr11_72755512_-exonic
ADediting_278028chr11_72755514_-exonic
ADediting_278029chr11_72755529_-exonic
ADediting_278030chr11_72755530_-exonic
ADediting_278031chr11_72755557_-exonic
ADediting_278032chr11_72755592_-exonic
ADediting_278033chr11_72755606_-exonic
ADediting_278034chr11_72756978_-intronic
ADediting_278035chr11_72757032_-intronic
ADediting_278036chr11_72757033_-intronic
ADediting_278037chr11_72757061_-intronic
ADediting_278038chr11_72757140_-intronic
ADediting_278039chr11_72759978_-intronic
ADediting_278040chr11_72759996_-intronic
ADediting_278041chr11_72760067_-intronic
ADediting_278042chr11_72760082_-intronic
ADediting_278043chr11_72760085_-intronic
ADediting_278044chr11_72760091_-intronic
ADediting_278045chr11_72760096_-intronic
ADediting_278046chr11_72760097_-intronic
ADediting_278047chr11_72760104_-intronic
ADediting_278048chr11_72760129_-intronic
ADediting_278049chr11_72760312_-intronic
ADediting_278050chr11_72760316_-intronic
ADediting_278051chr11_72760351_-intronic
ADediting_278052chr11_72760364_-intronic
ADediting_278053chr11_72760391_-intronic
ADediting_278054chr11_72760401_-intronic
ADediting_278055chr11_72760429_-intronic
ADediting_278056chr11_72760460_-intronic
ADediting_278057chr11_72760472_-intronic
ADediting_278058chr11_72761494_-intronic
ADediting_278059chr11_72761500_-intronic
ADediting_278060chr11_72761512_-intronic
ADediting_278061chr11_72761514_-intronic
ADediting_278062chr11_72761522_-intronic
ADediting_278063chr11_72761539_-intronic
ADediting_278064chr11_72761540_-intronic
ADediting_278065chr11_72761545_-intronic
ADediting_278066chr11_72761565_-intronic
ADediting_278067chr11_72761601_-intronic
ADediting_278068chr11_72761645_-intronic
ADediting_278069chr11_72761663_-intronic
ADediting_278070chr11_72761669_-intronic
ADediting_278071chr11_72761676_-intronic
ADediting_278072chr11_72761688_-intronic
ADediting_278073chr11_72761718_-intronic
ADediting_278074chr11_72761740_-intronic
ADediting_278075chr11_72761742_-intronic
ADediting_278076chr11_72761743_-intronic
ADediting_278077chr11_72761968_-intronic
ADediting_278078chr11_72761994_-intronic
ADediting_278079chr11_72762015_-intronic
ADediting_278080chr11_72762028_-intronic
ADediting_278081chr11_72762031_-intronic
ADediting_278082chr11_72762034_-intronic
ADediting_278083chr11_72762035_-intronic
ADediting_278084chr11_72762037_-intronic
ADediting_278085chr11_72762041_-intronic
ADediting_278086chr11_72762066_-intronic
ADediting_278087chr11_72762086_-intronic
ADediting_278088chr11_72762090_-intronic
ADediting_278089chr11_72762099_-intronic
ADediting_278090chr11_72762104_-intronic
ADediting_278091chr11_72762127_-intronic
ADediting_278092chr11_72762153_-intronic
ADediting_278093chr11_72762158_-intronic
ADediting_278094chr11_72762176_-intronic
ADediting_278095chr11_72762198_-intronic
ADediting_278096chr11_72762205_-intronic
ADediting_278097chr11_72765011_-intronic
ADediting_278098chr11_72765017_-intronic
ADediting_278099chr11_72765051_-intronic
ADediting_278100chr11_72765080_-intronic
ADediting_278101chr11_72765154_-intronic
ADediting_278102chr11_72770382_-intronic
ADediting_278103chr11_72771446_-intronic
ADediting_278104chr11_72773294_-intronic
ADediting_278105chr11_72777123_-intronic
ADediting_278106chr11_72777831_-intronic
ADediting_278107chr11_72779374_-intronic
ADediting_278108chr11_72779400_-intronic
ADediting_278109chr11_72779407_-intronic
ADediting_278110chr11_72779412_-intronic
ADediting_278111chr11_72779420_-intronic
ADediting_278112chr11_72779426_-intronic
ADediting_278113chr11_72779429_-intronic
ADediting_278114chr11_72779443_-intronic
ADediting_278115chr11_72779448_-intronic
ADediting_278116chr11_72779452_-intronic
ADediting_278117chr11_72779512_-intronic
ADediting_278118chr11_72779519_-intronic
ADediting_278119chr11_72779536_-intronic
ADediting_278120chr11_72779547_-intronic
ADediting_278121chr11_72779574_-intronic
ADediting_278122chr11_72791442_-intronic
ADediting_278123chr11_72791591_-intronic
ADediting_278124chr11_72791595_-intronic
ADediting_278125chr11_72792188_-intronic
ADediting_278126chr11_72792258_-intronic
ADediting_278127chr11_72792259_-intronic
ADediting_1528623chr11_72732733_-intronic
ADediting_1528624chr11_72755383_-UTR3
ADediting_1528625chr11_72755416_-UTR3
ADediting_1528626chr11_72755464_-UTR3
ADediting_1528627chr11_72755475_-UTR3
ADediting_1528628chr11_72755481_-UTR3
ADediting_1528629chr11_72755489_-UTR3
ADediting_1528630chr11_72755506_-exonic
ADediting_1528631chr11_72756902_-intronic
ADediting_1528632chr11_72757082_-intronic
ADediting_1528633chr11_72760375_-intronic
ADediting_1528634chr11_72760431_-intronic
ADediting_1528635chr11_72760478_-intronic
ADediting_1528636chr11_72762139_-intronic
ADediting_1528637chr11_72765714_-intronic
ADediting_1528638chr11_72770316_-intronic
ADediting_1528639chr11_72770371_-intronic
ADediting_1528640chr11_72770411_-intronic
ADediting_1528641chr11_72770419_-intronic
ADediting_1528642chr11_72773308_-intronic
ADediting_1528643chr11_72779444_-intronic
ADediting_1528644chr11_72779480_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_277986chr11_72715168_-SINEMIRName=MIRb
ADediting_277987chr11_72715643_-SINEAluName=AluJr
ADediting_277988chr11_72715647_-SINEAluName=AluJr
ADediting_277989chr11_72715673_-SINEAluName=AluJr
ADediting_277990chr11_72715679_-SINEAluName=AluJr
ADediting_277991chr11_72715685_-SINEAluName=AluJr
ADediting_277992chr11_72715692_-SINEAluName=AluJr
ADediting_277993chr11_72715717_-SINEAluName=AluJr
ADediting_277994chr11_72715751_-SINEAluName=AluJr
ADediting_277995chr11_72715752_-SINEAluName=AluJr
ADediting_277996chr11_72715754_-SINEAluName=AluJr
ADediting_277997chr11_72715762_-SINEAluName=AluJr
ADediting_277998chr11_72715790_-SINEAluName=AluJr
ADediting_277999chr11_72732977_-SINEAluName=AluJb
ADediting_278000chr11_72734259_-SINEAluName=AluJr
ADediting_278001chr11_72735119_-SINEAluName=AluJb
ADediting_278002chr11_72735145_-SINEAluName=AluJb
ADediting_278003chr11_72735366_-SINEAluName=AluSx1
ADediting_278004chr11_72735367_-SINEAluName=AluSx1
ADediting_278005chr11_72735452_-SINEAluName=AluSx1
ADediting_278006chr11_72735484_-SINEAluName=AluSx1
ADediting_278007chr11_72735513_-SINEAluName=AluSx1
ADediting_278008chr11_72735557_-SINEAluName=AluSx1
ADediting_278009chr11_72735558_-SINEAluName=AluSx1
ADediting_278010chr11_72735582_-SINEAluName=AluSx1
ADediting_278013chr11_72749627_-SINEAluName=AluY
ADediting_278014chr11_72749694_-SINEAluName=AluY
ADediting_278015chr11_72749702_-SINEAluName=AluY
ADediting_278016chr11_72749782_-SINEAluName=AluY
ADediting_278017chr11_72749813_-SINEAluName=AluY
ADediting_278018chr11_72755396_-SINEAluName=AluSx1
ADediting_278019chr11_72755400_-SINEAluName=AluSx1
ADediting_278020chr11_72755408_-SINEAluName=AluSx1
ADediting_278021chr11_72755413_-SINEAluName=AluSx1
ADediting_278022chr11_72755426_-SINEAluName=AluSx1
ADediting_278023chr11_72755427_-SINEAluName=AluSx1
ADediting_278024chr11_72755448_-SINEAluName=AluSx1
ADediting_278025chr11_72755449_-SINEAluName=AluSx1
ADediting_278026chr11_72755504_-SINEAluName=AluSx1
ADediting_278027chr11_72755512_-SINEAluName=AluSx1
ADediting_278028chr11_72755514_-SINEAluName=AluSx1
ADediting_278029chr11_72755529_-SINEAluName=AluSx1
ADediting_278030chr11_72755530_-SINEAluName=AluSx1
ADediting_278031chr11_72755557_-SINEAluName=AluSx1
ADediting_278032chr11_72755592_-SINEAluName=AluSx1
ADediting_278033chr11_72755606_-SINEAluName=AluSx1
ADediting_278034chr11_72756978_-SINEAluName=AluSq2
ADediting_278035chr11_72757032_-SINEAluName=AluSq2
ADediting_278036chr11_72757033_-SINEAluName=AluSq2
ADediting_278037chr11_72757061_-SINEAluName=AluSq2
ADediting_278038chr11_72757140_-SINEAluName=AluSq2
ADediting_278039chr11_72759978_-SINEAluName=AluSc
ADediting_278040chr11_72759996_-SINEAluName=AluSc
ADediting_278041chr11_72760067_-SINEAluName=AluSc
ADediting_278042chr11_72760082_-SINEAluName=AluSc
ADediting_278043chr11_72760085_-SINEAluName=AluSc
ADediting_278044chr11_72760091_-SINEAluName=AluSc
ADediting_278045chr11_72760096_-SINEAluName=AluSc
ADediting_278046chr11_72760097_-SINEAluName=AluSc
ADediting_278047chr11_72760104_-SINEAluName=AluSc
ADediting_278048chr11_72760129_-SINEAluName=AluSc
ADediting_278049chr11_72760312_-SINEAluName=AluSq4
ADediting_278050chr11_72760316_-SINEAluName=AluSq4
ADediting_278051chr11_72760351_-SINEAluName=AluSq4
ADediting_278052chr11_72760364_-SINEAluName=AluSq4
ADediting_278053chr11_72760391_-SINEAluName=AluSq4
ADediting_278054chr11_72760401_-SINEAluName=AluSq4
ADediting_278055chr11_72760429_-SINEAluName=AluSq4
ADediting_278056chr11_72760460_-SINEAluName=AluSq4
ADediting_278057chr11_72760472_-SINEAluName=AluSq4
ADediting_278058chr11_72761494_-SINEAluName=AluSz
ADediting_278059chr11_72761500_-SINEAluName=AluSz
ADediting_278060chr11_72761512_-SINEAluName=AluSz
ADediting_278061chr11_72761514_-SINEAluName=AluSz
ADediting_278062chr11_72761522_-SINEAluName=AluSz
ADediting_278063chr11_72761539_-SINEAluName=AluSz
ADediting_278064chr11_72761540_-SINEAluName=AluSz
ADediting_278065chr11_72761545_-SINEAluName=AluSz
ADediting_278066chr11_72761565_-SINEAluName=AluSz
ADediting_278067chr11_72761601_-SINEAluName=AluSz
ADediting_278068chr11_72761645_-SINEAluName=AluSz
ADediting_278069chr11_72761663_-SINEAluName=AluSz
ADediting_278070chr11_72761669_-SINEAluName=AluSz
ADediting_278071chr11_72761676_-SINEAluName=AluSz
ADediting_278072chr11_72761688_-SINEAluName=AluSz
ADediting_278073chr11_72761718_-SINEAluName=AluSz
ADediting_278074chr11_72761740_-SINEAluName=AluSz
ADediting_278075chr11_72761742_-SINEAluName=AluSz
ADediting_278076chr11_72761743_-SINEAluName=AluSz
ADediting_278077chr11_72761968_-SINEAluName=AluSq2
ADediting_278078chr11_72761994_-SINEAluName=AluSq2
ADediting_278079chr11_72762015_-SINEAluName=AluSq2
ADediting_278080chr11_72762028_-SINEAluName=AluSq2
ADediting_278081chr11_72762031_-SINEAluName=AluSq2
ADediting_278082chr11_72762034_-SINEAluName=AluSq2
ADediting_278083chr11_72762035_-SINEAluName=AluSq2
ADediting_278084chr11_72762037_-SINEAluName=AluSq2
ADediting_278085chr11_72762041_-SINEAluName=AluSq2
ADediting_278086chr11_72762066_-SINEAluName=AluSq2
ADediting_278087chr11_72762086_-SINEAluName=AluSq2
ADediting_278088chr11_72762090_-SINEAluName=AluSq2
ADediting_278089chr11_72762099_-SINEAluName=AluSq2
ADediting_278090chr11_72762104_-SINEAluName=AluSq2
ADediting_278091chr11_72762127_-SINEAluName=AluSq2
ADediting_278092chr11_72762153_-SINEAluName=AluSq2
ADediting_278093chr11_72762158_-SINEAluName=AluSq2
ADediting_278094chr11_72762176_-SINEAluName=AluSq2
ADediting_278095chr11_72762198_-SINEAluName=AluSq2
ADediting_278096chr11_72762205_-SINEAluName=AluSq2
ADediting_278097chr11_72765011_-SINEAluName=AluSp
ADediting_278098chr11_72765017_-SINEAluName=AluSp
ADediting_278099chr11_72765051_-SINEAluName=AluSp
ADediting_278100chr11_72765080_-SINEAluName=AluSp
ADediting_278101chr11_72765154_-SINEAluName=AluSp
ADediting_278102chr11_72770382_-SINEAluName=AluSz6
ADediting_278103chr11_72771446_-SINEMIRName=MIR1_Amn
ADediting_278107chr11_72779374_-SINEAluName=AluSz
ADediting_278108chr11_72779400_-SINEAluName=AluSz
ADediting_278109chr11_72779407_-SINEAluName=AluSz
ADediting_278110chr11_72779412_-SINEAluName=AluSz
ADediting_278111chr11_72779420_-SINEAluName=AluSz
ADediting_278112chr11_72779426_-SINEAluName=AluSz
ADediting_278113chr11_72779429_-SINEAluName=AluSz
ADediting_278114chr11_72779443_-SINEAluName=AluSz
ADediting_278115chr11_72779448_-SINEAluName=AluSz
ADediting_278116chr11_72779452_-SINEAluName=AluSz
ADediting_278117chr11_72779512_-SINEAluName=AluSz
ADediting_278118chr11_72779519_-SINEAluName=AluSz
ADediting_278119chr11_72779536_-SINEAluName=AluSz
ADediting_278120chr11_72779547_-SINEAluName=AluSz
ADediting_278121chr11_72779574_-SINEAluName=AluSz
ADediting_278122chr11_72791442_-SINEAluName=AluSq2
ADediting_278123chr11_72791591_-SINEAluName=AluSq2
ADediting_278124chr11_72791595_-SINEAluName=AluSq2
ADediting_278125chr11_72792188_-SINEAluName=AluSx1
ADediting_278126chr11_72792258_-SINEAluName=AluSx1
ADediting_278127chr11_72792259_-SINEAluName=AluSx1
ADediting_1528623chr11_72732733_-SINEAluName=AluJb
ADediting_1528624chr11_72755383_-SINEAluName=AluSx1
ADediting_1528625chr11_72755416_-SINEAluName=AluSx1
ADediting_1528626chr11_72755464_-SINEAluName=AluSx1
ADediting_1528627chr11_72755475_-SINEAluName=AluSx1
ADediting_1528628chr11_72755481_-SINEAluName=AluSx1
ADediting_1528629chr11_72755489_-SINEAluName=AluSx1
ADediting_1528630chr11_72755506_-SINEAluName=AluSx1
ADediting_1528631chr11_72756902_-SINEAluName=AluSq2
ADediting_1528632chr11_72757082_-SINEAluName=AluSq2
ADediting_1528633chr11_72760375_-SINEAluName=AluSq4
ADediting_1528634chr11_72760431_-SINEAluName=AluSq4
ADediting_1528635chr11_72760478_-SINEAluName=AluSq4
ADediting_1528636chr11_72762139_-SINEAluName=AluSq2
ADediting_1528637chr11_72765714_-SINEAluName=AluSz
ADediting_1528638chr11_72770316_-SINEAluName=AluSz6
ADediting_1528639chr11_72770371_-SINEAluName=AluSz6
ADediting_1528640chr11_72770411_-SINEAluName=AluSz6
ADediting_1528641chr11_72770419_-SINEAluName=AluSz6
ADediting_1528643chr11_72779444_-SINEAluName=AluSz
ADediting_1528644chr11_72779480_-SINEAluName=AluSz

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RNA A-to-I editing events in the alternative splicing sites for ARAP1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ARAP1

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot
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boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
Soverview
Soverview
Soverview

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Soverview
Soverview
Soverview
Soverview
Soverview
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Soverview
ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for ARAP1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for ARAP1


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337758chr7_5495892_-ENSG00000186635.14ENST00000334211.12ARAP1-201hsa-miR-589-5pchr1172685506726855127mer-m87268550572685527159-22.8
ADediting_1337758chr7_5495892_-ENSG00000186635.14ENST00000359373.9ARAP1-202hsa-miR-589-5pchr1172685506726855127mer-m87268550572685527159-22.8
ADediting_1337758chr7_5495892_-ENSG00000186635.14ENST00000393605.7ARAP1-203hsa-miR-589-5pchr1172685506726855127mer-m87268550572685527159-22.8
ADediting_1337758chr7_5495892_-ENSG00000186635.14ENST00000393609.7ARAP1-204hsa-miR-589-5pchr1172685506726855127mer-m87268550572685527159-22.8
ADediting_1337758chr7_5495892_-ENSG00000186635.14ENST00000455638.6ARAP1-209hsa-miR-589-5pchr1172685506726855127mer-m87268550572685527159-22.8

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ARAP1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for ARAP1

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_278013chr11_72749627_-0.160062787735542-0.0799859404999150.00607857950375644-0.1555002660243084.42185269873749e-080.304662107488968
CERADediting_278022chr11_72755426_-0.05123079230719990.1594931421025343.83846402399954e-060.3670367217729950.002204455625786060.248102140126948
CERADediting_278023chr11_72755427_-0.05729047516149480.1555781520173961.72753544851647e-050.3430493282549370.02837039538296070.179035322021229
CERADediting_278025chr11_72755449_-0.04468126273474330.164182699715243.84984630550746e-050.3294210703702620.300373322215010.0851175740379939
CERADediting_278026chr11_72755504_-0.0125582010396140.2033691126572161.21460426222362e-070.4157865028881360.009659544000220850.210677152276541
CERADediting_278030chr11_72755530_-0.09479210720733050.1369096842887182.13187326284576e-050.3395341411790870.0008753549616706980.268939488164688
CERADediting_278034chr11_72756978_-0.03937314946182970.1684252702845030.0001715872890447410.3021283633760180.8517879794232230.0153830081882006
CERADediting_278035chr11_72757032_-0.06953722204468320.1486062905787331.04678663453359e-060.3863096616746760.003831495236832510.23476224125538
CERADediting_278036chr11_72757033_-0.06294715237587240.1522201635867584.77557107117518e-070.3973820772460720.01792784461326920.193066356522593
CERADediting_278037chr11_72757061_-0.09856637132291510.1353833460853388.40224853551852e-070.3894517759394810.0008835349313895490.26873775373872
CERADediting_278038chr11_72757140_-0.2704980276630390.09054359164437040.0001061484825834320.311189883121930.2237841879893530.0999160989595104
CERADediting_278039chr11_72759978_-0.08216530766482790.1423952459327150.0001208990560333720.3087636525043746.59930915043255e-050.319879093315988
DLPFCADediting_278049chr11_72760312_-0.4716856710733320.04102695603569870.491095527216365-0.03925149430828652.12623598469611e-090.331748299379786
CERADediting_278049chr11_72760312_-0.00838697217988790.2145179922060732.08977650879328e-060.3762091059275070.001647654730477640.254853848523839
CERADediting_278053chr11_72760391_-0.0007618513367920280.2719333648754168.05733538007013e-050.3162621360199850.04628743803373070.162982199581227
CERADediting_278055chr11_72760429_-0.04265009170151040.1657535722862055.2836091523613e-050.3238546265561110.03166017479097140.175542413422548
DLPFCADediting_278056chr11_72760460_-0.2168762890456870.07033354400392120.6409052362492050.0265943913497073.2925599775264e-080.307416262881734
CERADediting_278067chr11_72761601_-0.007029681058060110.219231342371081.31374382601969e-060.3830279555722450.001557984403145320.256131459820352
CERADediting_278068chr11_72761645_-0.00793120708381330.216019958514752.92026920515082e-060.3711958768410540.001764812479482540.253276813733732
CERADediting_278069chr11_72761663_-0.005083481179226210.2276502937941382.61429341757354e-050.3360834146299560.06089296023606020.153409841608411
CERADediting_278071chr11_72761676_-0.007747799798485220.2166460490865430.0001912561173563660.300039284321830.2112253650405680.102667543604515
DLPFCADediting_278092chr11_72762153_-0.0634068521733056-0.1055640179949420.000937183981446389-0.1870183164036554.93585242875564e-080.303627746429746
CERADediting_278097chr11_72765011_-0.0665522707520520.1502069485241313.33450617714627e-050.3319127910480590.1781587787558070.110524301682593
DLPFCADediting_278100chr11_72765080_-0.1811344927702310.07614913933805070.7127588102510160.02099221049300192.14892087714475e-090.331658097069298
CERADediting_278102chr11_72770382_-0.0003688233084757510.2870476836007522.47265991677931e-060.3736990482133040.002499668680188960.24513103636124
CERADediting_278108chr11_72779400_-0.01932845055568140.1908273817782620.0001253689633235170.3080829263862450.0001301918006516670.307373393876759
DLPFCADediting_278109chr11_72779407_-0.489394009272440.03940560374446350.384628654837694-0.04954840081112391.66293274321058e-120.386835244698931
CERADediting_278109chr11_72779407_-0.007278547617280650.2183098861086560.0001030953250667460.3117312143997730.0008377147934208560.269890661391694
DLPFCADediting_278111chr11_72779420_-0.8891184382338160.007950504707184080.1498079468802-0.08199188486947022.9005172281535e-090.329096655202697
CERADediting_278111chr11_72779420_-0.002473356522325780.2453825572637096.53277354726889e-060.3587772172490570.0008746201819343640.268957693880519
CERADediting_278113chr11_72779429_-0.01744752887653590.1938691696194821.47679829710712e-050.3456432481080040.0007653360910372850.271835521132331
CERADediting_278117chr11_72779512_-0.0108039786051640.2075873114862515.37610302547209e-050.323546330223530.06926307470401520.148750942716485
CERADediting_278118chr11_72779519_-0.04436349529001760.1644244645253916.07720221558578e-050.3213591786780680.01675567123323980.195059953864503
DLPFCADediting_278122chr11_72791442_-0.788437412299972-0.01530162564798020.0666151461354634-0.1043160831720772.00968362979043e-100.351110108875286
DLPFCADediting_278123chr11_72791591_-0.42654496141620.04531953039129020.086678930295789-0.09746419066303753.47143138938779e-220.51276046257795
DLPFCADediting_278124chr11_72791595_-0.5411505834422440.03483686769825170.0282713204528069-0.1245999454440643.45926716513457e-220.512776700509969

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC6.15509710314413e-090.3225643980507911.86387716274029e-090.3328652199012199.41709683707594e-300.584142373671764
AC1.38829394798185e-260.6072524580750712.18838671262104e-160.4883230840351432.05850698743542e-250.595797937761668
PCC9.82201473974876e-080.3740291021583286.23156202639629e-060.3203819285534622.95908284478774e-110.457193348841821
CER1.18342684737679e-090.4709834701489691.37882438481506e-170.624364746695442.83215967677969e-100.486217271775489
TCX0.00383592956129990.2347335635860680.0333379871412124-0.1738783697212442.81055831521902e-200.662121989372775
FP1.53692164821861e-100.4563339713222223.95561359299498e-060.3379624626788061.76249597400488e-200.622493238688497
IFG0.0007308709075213760.6303820969507310.0002274542552973570.6729927833855640.0004535852568307570.648584117796601
PG0.337977628979114-0.07064476225595410.308718249370524-0.07503773345392447.34734419783686e-110.454317999739611
STG0.007102888983546580.2916737671331910.2699368429628940.1217456777502682.8991458748821e-100.621157408270802

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Relation with AD stages for ARAP1

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_278022chr11_72755426_-0.0002376382435000170.346651287023762
CERADediting_278023chr11_72755427_-0.0007587754368301480.319222534116711
CERADediting_278030chr11_72755530_-0.001137833460911430.309013733878932
CERADediting_278039chr11_72759978_-0.001159919241252670.308520303596811
CERADediting_278049chr11_72760312_-0.0001360069217637260.358990396594405
CERADediting_278056chr11_72760460_-0.001361220693729160.304379662748593
CERADediting_278067chr11_72761601_-0.001124647550565520.309312504007946
CERADediting_278069chr11_72761663_-0.001300215901475250.305572125285008
CERADediting_278070chr11_72761669_-7.42463924046739e-050.371830640236636
CERADediting_278071chr11_72761676_-0.001250328204370130.30658573432894
CERADediting_278098chr11_72765017_-0.0006151911845054130.324370795757184
CERADediting_278113chr11_72779429_-0.001218465237309590.307252559944024
CERADediting_278120chr11_72779547_-0.001472721562193710.302320492049836

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER9.56886360665788e-100.546362581363041
TCX1.53727017647396e-080.515712568263553
IFG0.03929259923699340.414682064760879

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RelatedDrugs for ARAP1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ARAP1

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource