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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for WDR92

check button Gene summary
Gene informationGene symbol

WDR92

Gene ID

116143

Gene nameWD repeat domain 92
Synonyms-
Cytomap

2p14

Type of geneprotein-coding
DescriptionWD repeat-containing protein 92WD repeat-containing protein Monadmonadtesticular secretory protein Li 67
Modification date20200313
UniProtAcc

Q96MX6,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for WDR92

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_893275(68123911, -), ADediting_893276(68123925, -), ADediting_893277(68123952, -), ADediting_893278(68123954, -), ADediting_893279(68123964, -), ADediting_893280(68123977, -), ADediting_893281(68124017, -), ADediting_893282(68124037, -), ADediting_893283(68124066, -), ADediting_893284(68124140, -), ADediting_893285(68124158, -), ADediting_893286(68124220, -), ADediting_893287(68124237, -), ADediting_893288(68124269, -), ADediting_893289(68124280, -), ADediting_893290(68124295, -), ADediting_893291(68124304, -), ADediting_893292(68124309, -), ADediting_893293(68124318, -), ADediting_893294(68124321, -), ADediting_893295(68124341, -), ADediting_893296(68124373, -), ADediting_893297(68124395, -), ADediting_893298(68127073, -), ADediting_893299(68127103, -), ADediting_893300(68127138, -), ADediting_893301(68127143, -), ADediting_893302(68127170, -), ADediting_893303(68127393, -), ADediting_893304(68127411, -), ADediting_893305(68127417, -), ADediting_893306(68127421, -), ADediting_893307(68127449, -), ADediting_893308(68127464, -), ADediting_893309(68127471, -), ADediting_893310(68127476, -), ADediting_893311(68127489, -), ADediting_893312(68129010, -), ADediting_893313(68129022, -), ADediting_893314(68129032, -), ADediting_893315(68129084, -), ADediting_893316(68129104, -), ADediting_893317(68129119, -), ADediting_893318(68129145, -), ADediting_893319(68129167, -), ADediting_893320(68129180, -), ADediting_893321(68129181, -), ADediting_893322(68129184, -), ADediting_893323(68129205, -), ADediting_893324(68129246, -), ADediting_893325(68130203, -), ADediting_893326(68130223, -), ADediting_893327(68130227, -), ADediting_893328(68130233, -), ADediting_893329(68130242, -), ADediting_893330(68130268, -), ADediting_893331(68130269, -), ADediting_893332(68130285, -), ADediting_893333(68130295, -), ADediting_893334(68130305, -), ADediting_893335(68130310, -), ADediting_893336(68130311, -), ADediting_893337(68130314, -), ADediting_893338(68130324, -), ADediting_893339(68130335, -), ADediting_893340(68130355, -), ADediting_893341(68130359, -), ADediting_893342(68130397, -), ADediting_893343(68130402, -), ADediting_893344(68130403, -), ADediting_893345(68130411, -), ADediting_893346(68130416, -), ADediting_893347(68130425, -), ADediting_893348(68131012, -), ADediting_893349(68131013, -), ADediting_893350(68131027, -), ADediting_893351(68131044, -), ADediting_893352(68131048, -), ADediting_893353(68131054, -), ADediting_893354(68131113, -), ADediting_893355(68131124, -), ADediting_893356(68131185, -), ADediting_893357(68131190, -), ADediting_893358(68131191, -), ADediting_893359(68133289, -), ADediting_893360(68133303, -), ADediting_893361(68133315, -), ADediting_893362(68133319, -), ADediting_893363(68133332, -), ADediting_893364(68133358, -), ADediting_893365(68133367, -), ADediting_893366(68133371, -), ADediting_893367(68133375, -), ADediting_893368(68133400, -), ADediting_893369(68133406, -), ADediting_893370(68133409, -), ADediting_893371(68133412, -), ADediting_893372(68133413, -), ADediting_893373(68133414, -), ADediting_893374(68133415, -), ADediting_893375(68133418, -), ADediting_893376(68133431, -), ADediting_893377(68133587, -), ADediting_893378(68133604, -), ADediting_893379(68133605, -), ADediting_893380(68133615, -), ADediting_893381(68133637, -), ADediting_893382(68133641, -), ADediting_893383(68133670, -), ADediting_893384(68133671, -), ADediting_893385(68133677, -), ADediting_893386(68133708, -), ADediting_893387(68133726, -), ADediting_893388(68136135, -), ADediting_893389(68142355, -), ADediting_893390(68153799, -), ADediting_893391(68153834, -), ADediting_893392(68153837, -), ADediting_893393(68153876, -), ADediting_893394(68153889, -), ADediting_893395(68153890, -), ADediting_893396(68154518, -), ADediting_893397(68154901, -), ADediting_893398(68154982, -), ADediting_893399(68155235, -), ADediting_893400(68155418, -), ADediting_893401(68155437, -), ADediting_893402(68155467, -), ADediting_893403(68155472, -), ADediting_1564146(68129204, -), ADediting_1638970(68130336, -), ADediting_1638971(68133688, -), ADediting_1638972(68154990, -), ADediting_1638973(68154993, -),

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RNA editing positional annotations for WDR92 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_893275chr2_68123911_-intergenic
ADediting_893276chr2_68123925_-intergenic
ADediting_893277chr2_68123952_-intergenic
ADediting_893278chr2_68123954_-intergenic
ADediting_893279chr2_68123964_-intergenic
ADediting_893280chr2_68123977_-intergenic
ADediting_893281chr2_68124017_-intergenic
ADediting_893282chr2_68124037_-intergenic
ADediting_893283chr2_68124066_-intergenic
ADediting_893284chr2_68124140_-intergenic
ADediting_893285chr2_68124158_-intergenic
ADediting_893286chr2_68124220_-intergenic
ADediting_893287chr2_68124237_-intergenic
ADediting_893288chr2_68124269_-upstream
ADediting_893289chr2_68124280_-upstream
ADediting_893290chr2_68124295_-upstream
ADediting_893291chr2_68124304_-upstream
ADediting_893292chr2_68124309_-upstream
ADediting_893293chr2_68124318_-upstream
ADediting_893294chr2_68124321_-upstream
ADediting_893295chr2_68124341_-upstream
ADediting_893296chr2_68124373_-upstream
ADediting_893297chr2_68124395_-upstream
ADediting_893298chr2_68127073_-intergenic
ADediting_893299chr2_68127103_-intergenic
ADediting_893300chr2_68127138_-intergenic
ADediting_893301chr2_68127143_-intergenic
ADediting_893302chr2_68127170_-intergenic
ADediting_893303chr2_68127393_-intergenic
ADediting_893304chr2_68127411_-intergenic
ADediting_893305chr2_68127417_-intergenic
ADediting_893306chr2_68127421_-intergenic
ADediting_893307chr2_68127449_-intergenic
ADediting_893308chr2_68127464_-intergenic
ADediting_893309chr2_68127471_-intergenic
ADediting_893310chr2_68127476_-intergenic
ADediting_893311chr2_68127489_-intergenic
ADediting_893312chr2_68129010_-downstream
ADediting_893313chr2_68129022_-downstream
ADediting_893314chr2_68129032_-downstream
ADediting_893315chr2_68129084_-downstream
ADediting_893316chr2_68129104_-downstream
ADediting_893317chr2_68129119_-downstream
ADediting_893318chr2_68129145_-downstream
ADediting_893319chr2_68129167_-downstream
ADediting_893320chr2_68129180_-downstream
ADediting_893321chr2_68129181_-downstream
ADediting_893322chr2_68129184_-downstream
ADediting_893323chr2_68129205_-downstream
ADediting_893324chr2_68129246_-downstream
ADediting_893325chr2_68130203_-UTR3
ADediting_893326chr2_68130223_-UTR3
ADediting_893327chr2_68130227_-UTR3
ADediting_893328chr2_68130233_-UTR3
ADediting_893329chr2_68130242_-UTR3
ADediting_893330chr2_68130268_-UTR3
ADediting_893331chr2_68130269_-UTR3
ADediting_893332chr2_68130285_-UTR3
ADediting_893333chr2_68130295_-UTR3
ADediting_893334chr2_68130305_-UTR3
ADediting_893335chr2_68130310_-UTR3
ADediting_893336chr2_68130311_-UTR3
ADediting_893337chr2_68130314_-UTR3
ADediting_893338chr2_68130324_-UTR3
ADediting_893339chr2_68130335_-UTR3
ADediting_893340chr2_68130355_-UTR3
ADediting_893341chr2_68130359_-UTR3
ADediting_893342chr2_68130397_-UTR3
ADediting_893343chr2_68130402_-UTR3
ADediting_893344chr2_68130403_-UTR3
ADediting_893345chr2_68130411_-UTR3
ADediting_893346chr2_68130416_-UTR3
ADediting_893347chr2_68130425_-UTR3
ADediting_893348chr2_68131012_-UTR3
ADediting_893349chr2_68131013_-UTR3
ADediting_893350chr2_68131027_-UTR3
ADediting_893351chr2_68131044_-UTR3
ADediting_893352chr2_68131048_-UTR3
ADediting_893353chr2_68131054_-UTR3
ADediting_893354chr2_68131113_-UTR3
ADediting_893355chr2_68131124_-UTR3
ADediting_893356chr2_68131185_-UTR3
ADediting_893357chr2_68131190_-UTR3
ADediting_893358chr2_68131191_-UTR3
ADediting_893359chr2_68133289_-intronic
ADediting_893360chr2_68133303_-intronic
ADediting_893361chr2_68133315_-intronic
ADediting_893362chr2_68133319_-intronic
ADediting_893363chr2_68133332_-intronic
ADediting_893364chr2_68133358_-intronic
ADediting_893365chr2_68133367_-intronic
ADediting_893366chr2_68133371_-intronic
ADediting_893367chr2_68133375_-intronic
ADediting_893368chr2_68133400_-intronic
ADediting_893369chr2_68133406_-intronic
ADediting_893370chr2_68133409_-intronic
ADediting_893371chr2_68133412_-intronic
ADediting_893372chr2_68133413_-intronic
ADediting_893373chr2_68133414_-intronic
ADediting_893374chr2_68133415_-intronic
ADediting_893375chr2_68133418_-intronic
ADediting_893376chr2_68133431_-intronic
ADediting_893377chr2_68133587_-intronic
ADediting_893378chr2_68133604_-intronic
ADediting_893379chr2_68133605_-intronic
ADediting_893380chr2_68133615_-intronic
ADediting_893381chr2_68133637_-intronic
ADediting_893382chr2_68133641_-intronic
ADediting_893383chr2_68133670_-intronic
ADediting_893384chr2_68133671_-intronic
ADediting_893385chr2_68133677_-intronic
ADediting_893386chr2_68133708_-intronic
ADediting_893387chr2_68133726_-intronic
ADediting_893388chr2_68136135_-intronic
ADediting_893389chr2_68142355_-intronic
ADediting_893390chr2_68153799_-intronic
ADediting_893391chr2_68153834_-intronic
ADediting_893392chr2_68153837_-intronic
ADediting_893393chr2_68153876_-intronic
ADediting_893394chr2_68153889_-intronic
ADediting_893395chr2_68153890_-intronic
ADediting_893396chr2_68154518_-intronic
ADediting_893397chr2_68154901_-intronic
ADediting_893398chr2_68154982_-intronic
ADediting_893399chr2_68155235_-intronic
ADediting_893400chr2_68155418_-intronic
ADediting_893401chr2_68155437_-intronic
ADediting_893402chr2_68155467_-intronic
ADediting_893403chr2_68155472_-intronic
ADediting_1564146chr2_68129204_-downstream
ADediting_1638970chr2_68130336_-UTR3
ADediting_1638971chr2_68133688_-intronic
ADediting_1638972chr2_68154990_-intronic
ADediting_1638973chr2_68154993_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_893275chr2_68123911_-SINEAluName=AluJb
ADediting_893276chr2_68123925_-SINEAluName=AluJb
ADediting_893277chr2_68123952_-SINEAluName=AluJb
ADediting_893278chr2_68123954_-SINEAluName=AluJb
ADediting_893279chr2_68123964_-SINEAluName=AluJb
ADediting_893280chr2_68123977_-SINEAluName=AluJb
ADediting_893281chr2_68124017_-SINEAluName=AluJb
ADediting_893282chr2_68124037_-SINEAluName=AluJb
ADediting_893283chr2_68124066_-SINEAluName=AluJb
ADediting_893284chr2_68124140_-SINEAluName=AluSz
ADediting_893285chr2_68124158_-SINEAluName=AluSz
ADediting_893286chr2_68124220_-SINEAluName=AluSz
ADediting_893287chr2_68124237_-SINEAluName=AluSz
ADediting_893288chr2_68124269_-SINEAluName=AluSz
ADediting_893289chr2_68124280_-SINEAluName=AluSz
ADediting_893290chr2_68124295_-SINEAluName=AluSz
ADediting_893291chr2_68124304_-SINEAluName=AluSz
ADediting_893292chr2_68124309_-SINEAluName=AluSz
ADediting_893293chr2_68124318_-SINEAluName=AluSz
ADediting_893294chr2_68124321_-SINEAluName=AluSz
ADediting_893295chr2_68124341_-SINEAluName=AluSz
ADediting_893296chr2_68124373_-SINEAluName=AluSz
ADediting_893297chr2_68124395_-SINEAluName=AluSz
ADediting_893298chr2_68127073_-SINEAluName=AluSx
ADediting_893299chr2_68127103_-SINEAluName=AluSx
ADediting_893300chr2_68127138_-SINEAluName=AluSx
ADediting_893301chr2_68127143_-SINEAluName=AluSx
ADediting_893302chr2_68127170_-SINEAluName=AluSx
ADediting_893303chr2_68127393_-SINEAluName=AluJr
ADediting_893304chr2_68127411_-SINEAluName=AluJr
ADediting_893305chr2_68127417_-SINEAluName=AluJr
ADediting_893306chr2_68127421_-SINEAluName=AluJr
ADediting_893307chr2_68127449_-SINEAluName=AluJr
ADediting_893308chr2_68127464_-SINEAluName=AluJr
ADediting_893309chr2_68127471_-SINEAluName=AluJr
ADediting_893310chr2_68127476_-SINEAluName=AluJr
ADediting_893311chr2_68127489_-SINEAluName=AluJr
ADediting_893312chr2_68129010_-SINEAluName=AluSx
ADediting_893313chr2_68129022_-SINEAluName=AluSx
ADediting_893314chr2_68129032_-SINEAluName=AluSx
ADediting_893315chr2_68129084_-SINEAluName=AluSx
ADediting_893316chr2_68129104_-SINEAluName=AluSx
ADediting_893317chr2_68129119_-SINEAluName=AluSx
ADediting_893318chr2_68129145_-SINEAluName=AluSx
ADediting_893319chr2_68129167_-SINEAluName=AluSx
ADediting_893320chr2_68129180_-SINEAluName=AluSx
ADediting_893321chr2_68129181_-SINEAluName=AluSx
ADediting_893322chr2_68129184_-SINEAluName=AluSx
ADediting_893323chr2_68129205_-SINEAluName=AluSx
ADediting_893324chr2_68129246_-SINEAluName=AluSx
ADediting_893325chr2_68130203_-SINEAluName=AluSx3
ADediting_893326chr2_68130223_-SINEAluName=AluSx3
ADediting_893327chr2_68130227_-SINEAluName=AluSx3
ADediting_893328chr2_68130233_-SINEAluName=AluSx3
ADediting_893329chr2_68130242_-SINEAluName=AluSx3
ADediting_893330chr2_68130268_-SINEAluName=AluSx3
ADediting_893331chr2_68130269_-SINEAluName=AluSx3
ADediting_893332chr2_68130285_-SINEAluName=AluSx3
ADediting_893333chr2_68130295_-SINEAluName=AluSx3
ADediting_893334chr2_68130305_-SINEAluName=AluSx3
ADediting_893335chr2_68130310_-SINEAluName=AluSx3
ADediting_893336chr2_68130311_-SINEAluName=AluSx3
ADediting_893337chr2_68130314_-SINEAluName=AluSx3
ADediting_893338chr2_68130324_-SINEAluName=AluSx3
ADediting_893339chr2_68130335_-SINEAluName=AluSx3
ADediting_893340chr2_68130355_-SINEAluName=AluSx3
ADediting_893341chr2_68130359_-SINEAluName=AluSx3
ADediting_893342chr2_68130397_-SINEAluName=AluSx3
ADediting_893343chr2_68130402_-SINEAluName=AluSx3
ADediting_893344chr2_68130403_-SINEAluName=AluSx3
ADediting_893345chr2_68130411_-SINEAluName=AluSx3
ADediting_893346chr2_68130416_-SINEAluName=AluSx3
ADediting_893347chr2_68130425_-SINEAluName=AluSx3
ADediting_893348chr2_68131012_-SINEAluName=AluY
ADediting_893349chr2_68131013_-SINEAluName=AluY
ADediting_893350chr2_68131027_-SINEAluName=AluY
ADediting_893351chr2_68131044_-SINEAluName=AluY
ADediting_893352chr2_68131048_-SINEAluName=AluY
ADediting_893353chr2_68131054_-SINEAluName=AluY
ADediting_893354chr2_68131113_-SINEAluName=AluY
ADediting_893355chr2_68131124_-SINEAluName=AluY
ADediting_893356chr2_68131185_-SINEAluName=AluY
ADediting_893357chr2_68131190_-SINEAluName=AluY
ADediting_893358chr2_68131191_-SINEAluName=AluY
ADediting_893359chr2_68133289_-SINEAluName=AluSz6
ADediting_893360chr2_68133303_-SINEAluName=AluSz6
ADediting_893361chr2_68133315_-SINEAluName=AluSz6
ADediting_893362chr2_68133319_-SINEAluName=AluSz6
ADediting_893363chr2_68133332_-SINEAluName=AluSz6
ADediting_893364chr2_68133358_-SINEAluName=AluSz6
ADediting_893365chr2_68133367_-SINEAluName=AluSz6
ADediting_893366chr2_68133371_-SINEAluName=AluSz6
ADediting_893367chr2_68133375_-SINEAluName=AluSz6
ADediting_893368chr2_68133400_-SINEAluName=AluSz6
ADediting_893369chr2_68133406_-SINEAluName=AluSz6
ADediting_893370chr2_68133409_-SINEAluName=AluSz6
ADediting_893371chr2_68133412_-SINEAluName=AluSz6
ADediting_893372chr2_68133413_-SINEAluName=AluSz6
ADediting_893373chr2_68133414_-SINEAluName=AluSz6
ADediting_893374chr2_68133415_-SINEAluName=AluSz6
ADediting_893375chr2_68133418_-SINEAluName=AluSz6
ADediting_893376chr2_68133431_-SINEAluName=AluSz6
ADediting_893377chr2_68133587_-SINEAluName=AluSx1
ADediting_893378chr2_68133604_-SINEAluName=AluSx1
ADediting_893379chr2_68133605_-SINEAluName=AluSx1
ADediting_893380chr2_68133615_-SINEAluName=AluSx1
ADediting_893381chr2_68133637_-SINEAluName=AluSx1
ADediting_893382chr2_68133641_-SINEAluName=AluSx1
ADediting_893383chr2_68133670_-SINEAluName=AluSx1
ADediting_893384chr2_68133671_-SINEAluName=AluSx1
ADediting_893385chr2_68133677_-SINEAluName=AluSx1
ADediting_893386chr2_68133708_-SINEAluName=AluSx1
ADediting_893387chr2_68133726_-SINEAluName=AluSx1
ADediting_893388chr2_68136135_-SINEAluName=AluJr
ADediting_893389chr2_68142355_-SINEAluName=AluSx
ADediting_893390chr2_68153799_-SINEAluName=AluSc5
ADediting_893391chr2_68153834_-SINEAluName=AluSc5
ADediting_893392chr2_68153837_-SINEAluName=AluSc5
ADediting_893393chr2_68153876_-SINEAluName=AluSc5
ADediting_893394chr2_68153889_-SINEAluName=AluSc5
ADediting_893395chr2_68153890_-SINEAluName=AluSc5
ADediting_893396chr2_68154518_-SINEAluName=AluY
ADediting_893397chr2_68154901_-SINEAluName=AluJb
ADediting_893398chr2_68154982_-SINEAluName=AluJb
ADediting_893399chr2_68155235_-SINEAluName=AluSx
ADediting_893400chr2_68155418_-SINEAluName=AluSx
ADediting_893401chr2_68155437_-SINEAluName=AluSx
ADediting_893402chr2_68155467_-SINEAluName=AluSx
ADediting_893403chr2_68155472_-SINEAluName=AluSx
ADediting_1564146chr2_68129204_-SINEAluName=AluSx
ADediting_1638970chr2_68130336_-SINEAluName=AluSx3
ADediting_1638971chr2_68133688_-SINEAluName=AluSx1
ADediting_1638972chr2_68154990_-SINEAluName=AluJb
ADediting_1638973chr2_68154993_-SINEAluName=AluJb

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RNA A-to-I editing events in the alternative splicing sites for WDR92

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for WDR92

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for WDR92

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for WDR92

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_893325chr2_68130203_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-324-3pchr268130203681302097mer-m86813020268130228145-27.48
ADediting_893325chr2_68130203_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-4690-3pchr268130198681302058mer-1a6813019868130217157-23.66
ADediting_893325chr2_68130203_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-5685chr268130198681302058mer-1a6813019868130221162-24.48
ADediting_893327chr2_68130227_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-10400-3pchr268130223681302297mer-m86813022268130243140-21.46
ADediting_893327chr2_68130227_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-4437chr268130223681302308mer-1a6813022368130243146-19.6
ADediting_893327chr2_68130227_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-4674chr268130223681302297mer-m86813022268130242147-22.8
ADediting_893331chr2_68130269_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-513a-5pchr268130268681302747mer-m86813026768130284140-18.01
ADediting_893334chr2_68130305_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-153-5pchr268130305681303117mer-m86813030468130326144-8.17
ADediting_893334chr2_68130305_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-3680-3pchr268130300681303078mer-1a6813030068130322140-14.25
ADediting_893335chr2_68130310_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-325chr268130309681303168mer-1a6813030968130330143-11
ADediting_893336chr2_68130311_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-222-5pchr268130309681303168mer-1a6813030968130333147-11.65
ADediting_893336chr2_68130311_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-30a-3pchr268130307681303148mer-1a6813030768130332152-13
ADediting_893336chr2_68130311_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-30d-3pchr268130307681303148mer-1a6813030768130332152-13.69
ADediting_893336chr2_68130311_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-30e-3pchr268130307681303148mer-1a6813030768130331151-11.5
ADediting_893336chr2_68130311_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-936chr268130310681303178mer-1a6813031068130331151-18.71
ADediting_893337chr2_68130314_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-374b-3pchr268130309681303168mer-1a6813030968130331147-10.02
ADediting_893339chr2_68130335_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-3190-5pchr268130335681303417mer-m86813033468130353154-19.64
ADediting_893342chr2_68130397_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-371a-3pchr268130392681303987mer-m86813039168130413145-17.36
ADediting_893344chr2_68130403_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-513a-5pchr268130402681304087mer-m86813040168130421147-19.64
ADediting_893345chr2_68130411_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-4634chr268130407681304137mer-m86813040668130425151-20.95
ADediting_893346chr2_68130416_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-6807-5pchr268130411681304177mer-m86813041068130432144-19.77
ADediting_893347chr2_68130425_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-6075chr268130425681304317mer-m86813042468130444140-21.41
ADediting_893348chr2_68131012_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-4284chr268131010681310167mer-m86813100968131026148-20.34
ADediting_893348chr2_68131012_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-4437chr268131009681310157mer-m86813100868131028145-18.43
ADediting_893351chr2_68131044_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-646chr268131042681310487mer-m86813104168131060144-17.6
ADediting_893353chr2_68131054_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-140-3pchr268131052681310587mer-m86813105168131071141-17.51
ADediting_893354chr2_68131113_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-412-3pchr268131113681311197mer-m86813111268131134151-19.82
ADediting_893354chr2_68131113_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-4508chr268131108681311147mer-m86813110768131123140-21.85
ADediting_893354chr2_68131113_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-6754-3pchr268131113681311197mer-m86813111268131132144-16.46
ADediting_893355chr2_68131124_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-3157-5pchr268131123681311297mer-m86813112268131143159-20.57
ADediting_893356chr2_68131185_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-371a-3pchr268131180681311867mer-m86813117968131201153-22.17
ADediting_893357chr2_68131190_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-3199chr268131185681311917mer-1a6813118568131204141-22.83
ADediting_893358chr2_68131191_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-513a-5pchr268131190681311967mer-m86813118968131206148-20.07
ADediting_893358chr2_68131191_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-638chr268131185681311917mer-1a6813118568131209151-32.12

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1638970chr2_68130336_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-4435chr268130335681303428mer-1a6813033568130355146-18.86
ADediting_1638970chr2_68130336_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-4781-3pchr268130332681303387mer-m86813033168130349144-13.86
ADediting_893326chr2_68130223_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-1343-3pchr268130220681302267mer-m86813021968130242143-22.21
ADediting_893326chr2_68130223_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-6742-3pchr268130220681302278mer-1a6813022068130239145-14.93
ADediting_893326chr2_68130223_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-6783-3pchr268130220681302267mer-m86813021968130239146-16.82
ADediting_893328chr2_68130233_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-8062chr268130231681302377mer-m86813023068130250141-10.43
ADediting_893329chr2_68130242_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-1976chr268130237681302448mer-1a6813023768130257149-21.37
ADediting_893329chr2_68130242_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-6747-3pchr268130239681302468mer-1a6813023968130260150-24.11
ADediting_893330chr2_68130268_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-10399-5pchr268130267681302737mer-m86813026668130285141-12.33
ADediting_893330chr2_68130268_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-6504-3pchr268130267681302737mer-m86813026668130287152-15.51
ADediting_893330chr2_68130268_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-8070chr268130263681302697mer-m86813026268130282153-16.94
ADediting_893331chr2_68130269_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-10399-5pchr268130267681302737mer-m86813026668130285141-12.33
ADediting_893331chr2_68130269_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-6504-3pchr268130267681302737mer-m86813026668130287152-15.51
ADediting_893331chr2_68130269_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-7151-3pchr268130268681302758mer-1a6813026868130288140-11.91
ADediting_893333chr2_68130295_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-4735-5pchr268130294681303007mer-m86813029368130314140-4.28
ADediting_893337chr2_68130314_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-6832-5pchr268130313681303197mer-m86813031268130334142-18.17
ADediting_893338chr2_68130324_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-2052chr268130323681303297mer-m86813032268130341143-8.39
ADediting_893339chr2_68130335_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-4716-5pchr268130330681303367mer-m86813032968130350140-11.3
ADediting_893339chr2_68130335_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-4781-3pchr268130332681303387mer-m86813033168130349144-13.86
ADediting_893341chr2_68130359_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-378a-5pchr268130355681303628mer-1a6813035568130377148-18.03
ADediting_893342chr2_68130397_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-512-3pchr268130392681303987mer-m86813039168130412149-15.51
ADediting_893342chr2_68130397_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-6128chr268130396681304027mer-m86813039568130413155-15.19
ADediting_893343chr2_68130402_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-10399-5pchr268130401681304077mer-m86813040068130420140-11.64
ADediting_893343chr2_68130402_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-6504-3pchr268130401681304077mer-m86813040068130419140-7.96
ADediting_893344chr2_68130403_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-10399-5pchr268130401681304077mer-m86813040068130420140-11.64
ADediting_893344chr2_68130403_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-6504-3pchr268130401681304077mer-m86813040068130419140-7.96
ADediting_893344chr2_68130403_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-7151-3pchr268130402681304098mer-1a6813040268130418145-16.74
ADediting_893350chr2_68131027_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-1976chr268131022681310298mer-1a6813102268131042149-21.37
ADediting_893350chr2_68131027_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-6747-3pchr268131024681310318mer-1a6813102468131045150-24.11
ADediting_893351chr2_68131044_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-562chr268131041681310477mer-m86813104068131060151-11.75
ADediting_893351chr2_68131044_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-5697chr268131040681310467mer-m86813103968131058148-14.12
ADediting_893352chr2_68131048_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-3117-3pchr268131048681310547mer-m86813104768131065155-19.34
ADediting_893353chr2_68131054_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-4759chr268131048681310558mer-1a6813104868131070151-20.06
ADediting_893354chr2_68131113_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-193b-5pchr268131109681311157mer-m86813110868131129142-17.74
ADediting_893356chr2_68131185_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-4731-5pchr268131182681311887mer-1a6813118268131202146-26.76
ADediting_893356chr2_68131185_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-512-3pchr268131180681311867mer-m86813117968131200152-15.9
ADediting_893356chr2_68131185_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-6506-5pchr268131184681311907mer-m86813118368131205144-12.88
ADediting_893357chr2_68131190_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-10399-5pchr268131189681311957mer-m86813118868131209148-11.21
ADediting_893357chr2_68131190_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-6504-3pchr268131189681311957mer-m86813118868131209153-14.35
ADediting_893358chr2_68131191_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-10399-5pchr268131189681311957mer-m86813118868131209148-11.21
ADediting_893358chr2_68131191_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-6504-3pchr268131189681311957mer-m86813118868131209153-14.35

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1535951chr14_100874558_+ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-337-3pchr268129999681300068mer-1a6812999968130020145-10.45
ADediting_1643790chr3_121049689_+ENSG00000243667.7ENST00000406245.6WDR92-202hsa-miR-5682chr268134196681342038mer-1a6813419668134216153-22.12
ADediting_1643790chr3_121049689_+ENSG00000243667.7ENST00000409164.1WDR92-203hsa-miR-5682chr268134196681342038mer-1a6813419668134216153-22.12

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000243667.7ENST00000295121.11WDR92-201hsa-miR-589-3pchr268130629681306357mer-m86813062868130651155-13
ADediting_843620chr2_207754818_+ENSG00000243667.7ENST00000457114.5WDR92-204hsa-miR-4775chr268131790681317967mer-m86813178968131809152-8.31

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for WDR92

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000295121.11protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_893325ENST00000295121.11chr2_68130203_-2193-809.00-805.10-839.30
ADediting_893326ENST00000295121.11chr2_68130223_-2173-804.40-805.10-839.30
ADediting_893327ENST00000295121.11chr2_68130227_-2169-805.90-805.10-839.30
ADediting_893328ENST00000295121.11chr2_68130233_-2163-804.70-805.10-839.30
ADediting_893329ENST00000295121.11chr2_68130242_-2154-805.10-805.10-839.30
ADediting_893330ENST00000295121.11chr2_68130268_-2128-808.40-805.10-839.30
ADediting_893331ENST00000295121.11chr2_68130269_-2127-805.20-805.10-839.30
ADediting_893332ENST00000295121.11chr2_68130285_-2111-804.00-805.10-839.30
ADediting_893333ENST00000295121.11chr2_68130295_-2101-804.80-805.10-839.30
ADediting_893334ENST00000295121.11chr2_68130305_-2091-805.10-805.10-839.30
ADediting_893335ENST00000295121.11chr2_68130310_-2086-805.10-805.10-839.30
ADediting_893336ENST00000295121.11chr2_68130311_-2085-805.10-805.10-839.30
ADediting_893337ENST00000295121.11chr2_68130314_-2082-807.10-805.10-839.30
ADediting_893338ENST00000295121.11chr2_68130324_-2072-805.40-805.10-839.30
ADediting_893339ENST00000295121.11chr2_68130335_-2061-805.40-805.10-839.30
ADediting_1638970ENST00000295121.11chr2_68130336_-2060-806.10-805.10-839.30
ADediting_893340ENST00000295121.11chr2_68130355_-2041-805.70-805.10-839.30
ADediting_893341ENST00000295121.11chr2_68130359_-2037-804.40-805.10-839.30
ADediting_893342ENST00000295121.11chr2_68130397_-1999-804.40-805.10-839.30
ADediting_893343ENST00000295121.11chr2_68130402_-1994-805.50-805.10-839.30
ADediting_893344ENST00000295121.11chr2_68130403_-1993-805.80-805.10-839.30
ADediting_893345ENST00000295121.11chr2_68130411_-1985-804.70-805.10-839.30
ADediting_893346ENST00000295121.11chr2_68130416_-1980-805.10-805.10-839.30
ADediting_893347ENST00000295121.11chr2_68130425_-1971-804.40-805.10-839.30
ADediting_893348ENST00000295121.11chr2_68131012_-1384-808.10-805.10-839.30
ADediting_893349ENST00000295121.11chr2_68131013_-1383-808.60-805.10-839.30
ADediting_893350ENST00000295121.11chr2_68131027_-1369-805.00-805.10-839.30
ADediting_893351ENST00000295121.11chr2_68131044_-1352-805.10-805.10-839.30
ADediting_893352ENST00000295121.11chr2_68131048_-1348-808.30-805.10-839.30
ADediting_893353ENST00000295121.11chr2_68131054_-1342-806.50-805.10-839.30
ADediting_893354ENST00000295121.11chr2_68131113_-1283-806.50-805.10-839.30
ADediting_893355ENST00000295121.11chr2_68131124_-1272-805.10-805.10-839.30
ADediting_893356ENST00000295121.11chr2_68131185_-1211-804.70-805.10-839.30
ADediting_893357ENST00000295121.11chr2_68131190_-1206-808.20-805.10-839.30
ADediting_893358ENST00000295121.11chr2_68131191_-1205-807.80-805.10-839.30

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for WDR92

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC5.42445265087934e-230.5212280057328428.17533458945671e-130.3917731905191641.06058058459819e-340.622859105786622
AC2.83389805843222e-1030.9206175646783331.18900309896039e-650.832852360957352.17431215742039e-090.367023897935758
PCC1.73286568009016e-580.8649372682059431.1013243668042e-500.8339579069855210.0003063780957584160.258444135544035
CER4.29881111210716e-280.7476193990562655.80136045997353e-130.5446657082814250.1924136811234750.107017374719007
TCX7.41462824877742e-420.8438730731322272.92417922668808e-180.6343199614872670.09746847040183020.135822503476959
FP1.22147264996887e-330.7516712618769791.10330910332187e-260.6918515057933631.12990138287991e-060.355362551254589
IFG5.97047174725174e-050.7146987250440038.14453614781752e-050.705611777714870.1804259451746910.276790630586227
PG3.93766421866784e-630.885424479554194.81127672009026e-330.736340945979980.7308584706027310.0253892053820288
STG4.78699197176042e-160.7444875719573823.70791426116985e-080.5571450112772830.03099988172955250.235562958341257

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Relation with AD stages for WDR92

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_893305chr2_68127417_-0.000466000720422488-0.331051423286464
CERADediting_893307chr2_68127449_-0.000131108477038571-0.35978409240389
TCXADediting_893300chr2_68127138_-0.000462332636845208-0.334239986590059
TCXADediting_893301chr2_68127143_-0.00046536351655548-0.334083413902363
TCXADediting_893305chr2_68127417_-1.61384952039537e-05-0.405535885877061
TCXADediting_893308chr2_68127464_-5.69068014742998e-06-0.424711523863043

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.

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RelatedDrugs for WDR92

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for WDR92

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource