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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for OMA1 |
 Gene summary |
| Gene information | Gene symbol | OMA1 | Gene ID | 115209 |
| Gene name | OMA1 zinc metallopeptidase | |
| Synonyms | 2010001O09Rik|DAB1|MPRP-1|MPRP1|YKR087C|ZMPOMA1|peptidase | |
| Cytomap | 1p32.2-p32.1 | |
| Type of gene | protein-coding | |
| Description | metalloendopeptidase OMA1, mitochondrialOMA1 homolog, zinc metallopeptidaseOMA1 zinc metallopeptidase homologmetalloprotease-related protein 1overlapping activity with M-AAA proteaseoverlapping with the m-AAA protease 1 homologzinc metallopeptidase | |
| Modification date | 20200313 | |
| UniProtAcc | Q96E52, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for OMA1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_129663(58452043, -), ADediting_129664(58452048, -), ADediting_129665(58452049, -), ADediting_129666(58452061, -), ADediting_129667(58541516, -), ADediting_129668(58541533, -), ADediting_129669(58541534, -), ADediting_129670(58541540, -), ADediting_129671(58541573, -), ADediting_129672(58544655, -), ADediting_129673(58544667, -), ADediting_129674(58544685, -), ADediting_129675(58544686, -), ADediting_129676(58544690, -), ADediting_129677(58544691, -), ADediting_129678(58544718, -), ADediting_129679(58544722, -), ADediting_129680(58544758, -), ADediting_129681(58544767, -), ADediting_129682(58544771, -), ADediting_129683(58544772, -), ADediting_129684(58544773, -), ADediting_129685(58544787, -), ADediting_129686(58544821, -), ADediting_129687(58544826, -), ADediting_129688(58544836, -), ADediting_129689(58544869, -), ADediting_129690(58544875, -), ADediting_1520798(58541507, -), ADediting_1520799(58541555, -), ADediting_1520800(58541560, -), ADediting_1520801(58544764, -), |
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RNA editing positional annotations for OMA1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_129663 | chr1_58452043_- | intergenic |
| ADediting_129664 | chr1_58452048_- | intergenic |
| ADediting_129665 | chr1_58452049_- | intergenic |
| ADediting_129666 | chr1_58452061_- | intergenic |
| ADediting_129667 | chr1_58541516_- | UTR5 |
| ADediting_129668 | chr1_58541533_- | UTR5 |
| ADediting_129669 | chr1_58541534_- | UTR5 |
| ADediting_129670 | chr1_58541540_- | UTR5 |
| ADediting_129671 | chr1_58541573_- | UTR5 |
| ADediting_129672 | chr1_58544655_- | intronic |
| ADediting_129673 | chr1_58544667_- | intronic |
| ADediting_129674 | chr1_58544685_- | intronic |
| ADediting_129675 | chr1_58544686_- | intronic |
| ADediting_129676 | chr1_58544690_- | intronic |
| ADediting_129677 | chr1_58544691_- | intronic |
| ADediting_129678 | chr1_58544718_- | intronic |
| ADediting_129679 | chr1_58544722_- | intronic |
| ADediting_129680 | chr1_58544758_- | intronic |
| ADediting_129681 | chr1_58544767_- | intronic |
| ADediting_129682 | chr1_58544771_- | intronic |
| ADediting_129683 | chr1_58544772_- | intronic |
| ADediting_129684 | chr1_58544773_- | intronic |
| ADediting_129685 | chr1_58544787_- | intronic |
| ADediting_129686 | chr1_58544821_- | intronic |
| ADediting_129687 | chr1_58544826_- | intronic |
| ADediting_129688 | chr1_58544836_- | intronic |
| ADediting_129689 | chr1_58544869_- | intronic |
| ADediting_129690 | chr1_58544875_- | intronic |
| ADediting_1520798 | chr1_58541507_- | UTR5 |
| ADediting_1520799 | chr1_58541555_- | UTR5 |
| ADediting_1520800 | chr1_58541560_- | UTR5 |
| ADediting_1520801 | chr1_58544764_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_129663 | chr1_58452043_- | SINE | Alu | Name=AluSp |
| ADediting_129664 | chr1_58452048_- | SINE | Alu | Name=AluSp |
| ADediting_129665 | chr1_58452049_- | SINE | Alu | Name=AluSp |
| ADediting_129666 | chr1_58452061_- | SINE | Alu | Name=AluSp |
| ADediting_129667 | chr1_58541516_- | SINE | Alu | Name=AluSx |
| ADediting_129668 | chr1_58541533_- | SINE | Alu | Name=AluSx |
| ADediting_129669 | chr1_58541534_- | SINE | Alu | Name=AluSx |
| ADediting_129670 | chr1_58541540_- | SINE | Alu | Name=AluSx |
| ADediting_129671 | chr1_58541573_- | SINE | Alu | Name=AluSx |
| ADediting_129672 | chr1_58544655_- | SINE | Alu | Name=AluSz6 |
| ADediting_129673 | chr1_58544667_- | SINE | Alu | Name=AluSz6 |
| ADediting_129674 | chr1_58544685_- | SINE | Alu | Name=AluSz6 |
| ADediting_129675 | chr1_58544686_- | SINE | Alu | Name=AluSz6 |
| ADediting_129676 | chr1_58544690_- | SINE | Alu | Name=AluSz6 |
| ADediting_129677 | chr1_58544691_- | SINE | Alu | Name=AluSz6 |
| ADediting_129678 | chr1_58544718_- | SINE | Alu | Name=AluSz6 |
| ADediting_129679 | chr1_58544722_- | SINE | Alu | Name=AluSz6 |
| ADediting_129680 | chr1_58544758_- | SINE | Alu | Name=AluSz6 |
| ADediting_129681 | chr1_58544767_- | SINE | Alu | Name=AluSz6 |
| ADediting_129682 | chr1_58544771_- | SINE | Alu | Name=AluSz6 |
| ADediting_129683 | chr1_58544772_- | SINE | Alu | Name=AluSz6 |
| ADediting_129684 | chr1_58544773_- | SINE | Alu | Name=AluSz6 |
| ADediting_129685 | chr1_58544787_- | SINE | Alu | Name=AluSz6 |
| ADediting_129686 | chr1_58544821_- | SINE | Alu | Name=AluSz6 |
| ADediting_129687 | chr1_58544826_- | SINE | Alu | Name=AluSz6 |
| ADediting_129688 | chr1_58544836_- | SINE | Alu | Name=AluSz6 |
| ADediting_129689 | chr1_58544869_- | SINE | Alu | Name=AluSz6 |
| ADediting_129690 | chr1_58544875_- | SINE | Alu | Name=AluSz6 |
| ADediting_1520798 | chr1_58541507_- | SINE | Alu | Name=AluSx |
| ADediting_1520799 | chr1_58541555_- | SINE | Alu | Name=AluSx |
| ADediting_1520800 | chr1_58541560_- | SINE | Alu | Name=AluSx |
| ADediting_1520801 | chr1_58544764_- | SINE | Alu | Name=AluSz6 |
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RNA A-to-I editing events in the alternative splicing sites for OMA1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for OMA1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |