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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for ELFN2 |
 Gene summary |
| Gene information | Gene symbol | ELFN2 | Gene ID | 114794 |
| Gene name | extracellular leucine rich repeat and fibronectin type III domain containing 2 | |
| Synonyms | LRRC62|PPP1R29 | |
| Cytomap | 22q13.1 | |
| Type of gene | protein-coding | |
| Description | protein phosphatase 1 regulatory subunit 29dJ63G5.3 (putative Leucine rich protein)leucine-rich repeat and fibronectin type-III domain-containing protein 6leucine-rich repeat-containing protein 62 | |
| Modification date | 20200313 | |
| UniProtAcc | Q5R3F8, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| ELFN2 | GO:0010923 | negative regulation of phosphatase activity | 19389623 |
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RNA A-to-I events for ELFN2 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_988968(37369569, -), ADediting_988969(37374134, -), ADediting_988970(37382635, -), ADediting_988971(37384952, -), ADediting_988972(37384955, -), ADediting_988973(37388476, -), ADediting_988974(37389861, -), ADediting_988975(37390303, -), ADediting_988976(37392075, -), ADediting_988977(37397084, -), ADediting_988978(37405158, -), ADediting_988979(37405165, -), ADediting_988980(37405201, -), ADediting_988981(37405231, -), ADediting_988982(37405330, -), ADediting_988983(37405388, -), ADediting_988984(37405940, -), ADediting_988985(37406080, -), ADediting_988986(37407771, -), ADediting_988987(37407773, -), ADediting_988988(37407783, -), ADediting_988989(37407795, -), ADediting_988990(37408491, -), ADediting_988991(37413918, -), ADediting_988992(37414028, -), ADediting_988993(37422462, -), ADediting_988994(37422513, -), ADediting_988995(37422522, -), ADediting_988996(37422539, -), ADediting_988997(37422542, -), ADediting_988998(37422565, -), ADediting_988999(37422575, -), ADediting_989000(37422583, -), ADediting_989001(37422593, -), ADediting_989002(37422596, -), ADediting_989003(37422750, -), ADediting_989004(37422758, -), ADediting_989005(37422788, -), ADediting_989006(37422798, -), ADediting_989007(37422822, -), ADediting_989008(37422874, -), ADediting_989009(37422876, -), ADediting_989010(37423201, -), ADediting_1570493(37388714, -), ADediting_1570494(37422841, -), |
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RNA editing positional annotations for ELFN2 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| ADediting_988969 | chr22_37374134_- | synonymous SNV | ENST00000613079.4 | c.A1401G | p.V467V | . | . | . |
| ADediting_988969 | chr22_37374134_- | synonymous SNV | ENST00000402918.7 | c.A1401G | p.V467V | . | . | . |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_988968 | chr22_37369569_- | ncRNA_intronic |
| ADediting_988969 | chr22_37374134_- | exonic |
| ADediting_988970 | chr22_37382635_- | ncRNA_intronic |
| ADediting_988971 | chr22_37384952_- | ncRNA_exonic |
| ADediting_988972 | chr22_37384955_- | ncRNA_exonic |
| ADediting_988973 | chr22_37388476_- | ncRNA_intronic |
| ADediting_988974 | chr22_37389861_- | ncRNA_intronic |
| ADediting_988975 | chr22_37390303_- | ncRNA_intronic |
| ADediting_988976 | chr22_37392075_- | ncRNA_intronic |
| ADediting_988977 | chr22_37397084_- | ncRNA_intronic |
| ADediting_988978 | chr22_37405158_- | ncRNA_intronic |
| ADediting_988979 | chr22_37405165_- | ncRNA_intronic |
| ADediting_988980 | chr22_37405201_- | ncRNA_intronic |
| ADediting_988981 | chr22_37405231_- | ncRNA_intronic |
| ADediting_988982 | chr22_37405330_- | ncRNA_intronic |
| ADediting_988983 | chr22_37405388_- | ncRNA_intronic |
| ADediting_988984 | chr22_37405940_- | ncRNA_intronic |
| ADediting_988985 | chr22_37406080_- | ncRNA_intronic |
| ADediting_988986 | chr22_37407771_- | ncRNA_intronic |
| ADediting_988987 | chr22_37407773_- | ncRNA_intronic |
| ADediting_988988 | chr22_37407783_- | ncRNA_intronic |
| ADediting_988989 | chr22_37407795_- | ncRNA_intronic |
| ADediting_988990 | chr22_37408491_- | ncRNA_intronic |
| ADediting_988991 | chr22_37413918_- | ncRNA_intronic |
| ADediting_988992 | chr22_37414028_- | ncRNA_intronic |
| ADediting_988993 | chr22_37422462_- | ncRNA_intronic |
| ADediting_988994 | chr22_37422513_- | ncRNA_intronic |
| ADediting_988995 | chr22_37422522_- | ncRNA_intronic |
| ADediting_988996 | chr22_37422539_- | ncRNA_intronic |
| ADediting_988997 | chr22_37422542_- | ncRNA_intronic |
| ADediting_988998 | chr22_37422565_- | ncRNA_intronic |
| ADediting_988999 | chr22_37422575_- | ncRNA_intronic |
| ADediting_989000 | chr22_37422583_- | ncRNA_intronic |
| ADediting_989001 | chr22_37422593_- | ncRNA_intronic |
| ADediting_989002 | chr22_37422596_- | ncRNA_intronic |
| ADediting_989003 | chr22_37422750_- | ncRNA_intronic |
| ADediting_989004 | chr22_37422758_- | ncRNA_intronic |
| ADediting_989005 | chr22_37422788_- | ncRNA_intronic |
| ADediting_989006 | chr22_37422798_- | ncRNA_intronic |
| ADediting_989007 | chr22_37422822_- | ncRNA_intronic |
| ADediting_989008 | chr22_37422874_- | ncRNA_intronic |
| ADediting_989009 | chr22_37422876_- | ncRNA_intronic |
| ADediting_989010 | chr22_37423201_- | ncRNA_intronic |
| ADediting_1570493 | chr22_37388714_- | ncRNA_intronic |
| ADediting_1570494 | chr22_37422841_- | ncRNA_intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_988970 | chr22_37382635_- | SINE | Alu | Name=AluSz |
| ADediting_988971 | chr22_37384952_- | LINE | L2 | Name=L2c |
| ADediting_988972 | chr22_37384955_- | LINE | L2 | Name=L2c |
| ADediting_988973 | chr22_37388476_- | SINE | MIR | Name=MIRb |
| ADediting_988974 | chr22_37389861_- | LINE | L2 | Name=L2b |
| ADediting_988975 | chr22_37390303_- | SINE | MIR | Name=MIRc |
| ADediting_988977 | chr22_37397084_- | LINE | L2 | Name=L2b |
| ADediting_988978 | chr22_37405158_- | SINE | Alu | Name=AluSx |
| ADediting_988979 | chr22_37405165_- | SINE | Alu | Name=AluSx |
| ADediting_988980 | chr22_37405201_- | SINE | Alu | Name=AluSx |
| ADediting_988981 | chr22_37405231_- | SINE | Alu | Name=AluSx |
| ADediting_988982 | chr22_37405330_- | SINE | Alu | Name=AluSx |
| ADediting_988983 | chr22_37405388_- | SINE | Alu | Name=AluSx |
| ADediting_988984 | chr22_37405940_- | SINE | Alu | Name=AluJb |
| ADediting_988985 | chr22_37406080_- | SINE | Alu | Name=AluJb |
| ADediting_988986 | chr22_37407771_- | SINE | Alu | Name=AluY |
| ADediting_988987 | chr22_37407773_- | SINE | Alu | Name=AluY |
| ADediting_988988 | chr22_37407783_- | SINE | Alu | Name=AluY |
| ADediting_988989 | chr22_37407795_- | SINE | Alu | Name=AluY |
| ADediting_988990 | chr22_37408491_- | SINE | MIR | Name=MIRb |
| ADediting_988991 | chr22_37413918_- | SINE | MIR | Name=MIRb |
| ADediting_988992 | chr22_37414028_- | SINE | MIR | Name=MIRb |
| ADediting_988993 | chr22_37422462_- | SINE | Alu | Name=AluSg |
| ADediting_988994 | chr22_37422513_- | SINE | Alu | Name=AluSg |
| ADediting_988995 | chr22_37422522_- | SINE | Alu | Name=AluSg |
| ADediting_988996 | chr22_37422539_- | SINE | Alu | Name=AluSg |
| ADediting_988997 | chr22_37422542_- | SINE | Alu | Name=AluSg |
| ADediting_988998 | chr22_37422565_- | SINE | Alu | Name=AluSg |
| ADediting_988999 | chr22_37422575_- | SINE | Alu | Name=AluSg |
| ADediting_989000 | chr22_37422583_- | SINE | Alu | Name=AluSg |
| ADediting_989001 | chr22_37422593_- | SINE | Alu | Name=AluSg |
| ADediting_989002 | chr22_37422596_- | SINE | Alu | Name=AluSg |
| ADediting_989003 | chr22_37422750_- | SINE | Alu | Name=AluSx |
| ADediting_989004 | chr22_37422758_- | SINE | Alu | Name=AluSx |
| ADediting_989005 | chr22_37422788_- | SINE | Alu | Name=AluSx |
| ADediting_989006 | chr22_37422798_- | SINE | Alu | Name=AluSx |
| ADediting_989007 | chr22_37422822_- | SINE | Alu | Name=AluSx |
| ADediting_989008 | chr22_37422874_- | SINE | Alu | Name=AluSx |
| ADediting_989009 | chr22_37422876_- | SINE | Alu | Name=AluSx |
| ADediting_1570493 | chr22_37388714_- | SINE | MIR | Name=MIRc |
| ADediting_1570494 | chr22_37422841_- | SINE | Alu | Name=AluSx |
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RNA A-to-I editing events in the alternative splicing sites for ELFN2 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ELFN2 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for ELFN2 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for ELFN2 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_988968 | chr22_37369569_- | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-3074-5p | chr22 | 37369565 | 37369572 | 8mer-1a | 37369565 | 37369585 | 141 | -20.95 |
| ADediting_988968 | chr22_37369569_- | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-3124-3p | chr22 | 37369564 | 37369570 | 7mer-m8 | 37369563 | 37369583 | 148 | -15.92 |
| ADediting_988968 | chr22_37369569_- | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-6747-3p | chr22 | 37369567 | 37369574 | 8mer-1a | 37369567 | 37369588 | 162 | -24.4 |
| ADediting_988968 | chr22_37369569_- | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-7152-5p | chr22 | 37369565 | 37369571 | 7mer-1a | 37369565 | 37369586 | 152 | -28.34 |
| ADediting_988968 | chr22_37369569_- | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-3074-5p | chr22 | 37369565 | 37369572 | 8mer-1a | 37369565 | 37369585 | 141 | -20.95 |
| ADediting_988968 | chr22_37369569_- | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-3124-3p | chr22 | 37369564 | 37369570 | 7mer-m8 | 37369563 | 37369583 | 148 | -15.92 |
| ADediting_988968 | chr22_37369569_- | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-6747-3p | chr22 | 37369567 | 37369574 | 8mer-1a | 37369567 | 37369588 | 162 | -24.4 |
| ADediting_988968 | chr22_37369569_- | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-7152-5p | chr22 | 37369565 | 37369571 | 7mer-1a | 37369565 | 37369586 | 152 | -28.34 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-5688 | chr22 | 37370824 | 37370830 | 7mer-m8 | 37370823 | 37370848 | 147 | -14.07 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-5688 | chr22 | 37370824 | 37370830 | 7mer-m8 | 37370823 | 37370848 | 147 | -14.07 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-589-5p | chr22 | 37370283 | 37370290 | 8mer-1a | 37370283 | 37370304 | 147 | -22.18 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-589-5p | chr22 | 37370283 | 37370290 | 8mer-1a | 37370283 | 37370304 | 147 | -22.18 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-4477b | chr22 | 37368025 | 37368031 | 7mer-m8 | 37368024 | 37368052 | 148 | -14.52 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-4477b | chr22 | 37370538 | 37370544 | 7mer-m8 | 37370537 | 37370558 | 145 | -11.64 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-4477b | chr22 | 37368025 | 37368031 | 7mer-m8 | 37368024 | 37368052 | 148 | -14.52 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-4477b | chr22 | 37370538 | 37370544 | 7mer-m8 | 37370537 | 37370558 | 145 | -11.64 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-381-3p | chr22 | 37368008 | 37368014 | 7mer-m8 | 37368007 | 37368025 | 146 | -20.94 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-381-3p | chr22 | 37368088 | 37368094 | 7mer-m8 | 37368087 | 37368108 | 150 | -15.42 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-381-3p | chr22 | 37368008 | 37368014 | 7mer-m8 | 37368007 | 37368025 | 146 | -20.94 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-381-3p | chr22 | 37368088 | 37368094 | 7mer-m8 | 37368087 | 37368108 | 150 | -15.42 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-641 | chr22 | 37372576 | 37372582 | 7mer-m8 | 37372575 | 37372598 | 147 | -15.27 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-641 | chr22 | 37372576 | 37372582 | 7mer-m8 | 37372575 | 37372598 | 147 | -15.27 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_107020 | chr1_37500952_- | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-5581-3p | chr22 | 37371019 | 37371025 | 7mer-m8 | 37371018 | 37371039 | 153 | -23.53 |
| ADediting_107020 | chr1_37500952_- | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-5581-3p | chr22 | 37371019 | 37371025 | 7mer-m8 | 37371018 | 37371039 | 153 | -23.53 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-589-5p | chr22 | 37371642 | 37371648 | 7mer-m8 | 37371641 | 37371661 | 144 | -17.02 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-589-5p | chr22 | 37371642 | 37371648 | 7mer-m8 | 37371641 | 37371661 | 144 | -17.02 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-151a-3p | chr22 | 37371346 | 37371352 | 7mer-m8 | 37371345 | 37371365 | 154 | -18.05 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-151a-3p | chr22 | 37371346 | 37371352 | 7mer-m8 | 37371345 | 37371365 | 154 | -18.05 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-4477b | chr22 | 37372844 | 37372851 | 8mer-1a | 37372844 | 37372866 | 155 | -13.04 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-4477b | chr22 | 37372844 | 37372851 | 8mer-1a | 37372844 | 37372866 | 155 | -13.04 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-4477b | chr22 | 37372844 | 37372851 | 8mer-1a | 37372844 | 37372866 | 155 | -13.04 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-4477b | chr22 | 37372844 | 37372851 | 8mer-1a | 37372844 | 37372866 | 155 | -13.04 |
| ADediting_291761 | chr11_93733708_- | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-1304-3p | chr22 | 37371777 | 37371783 | 7mer-m8 | 37371776 | 37371797 | 145 | -14.63 |
| ADediting_291761 | chr11_93733708_- | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-1304-3p | chr22 | 37371777 | 37371783 | 7mer-m8 | 37371776 | 37371797 | 145 | -14.63 |
| ADediting_496066 | chr15_66496985_- | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-4512 | chr22 | 37368207 | 37368213 | 7mer-m8 | 37368206 | 37368227 | 147 | -22.33 |
| ADediting_496066 | chr15_66496985_- | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-4512 | chr22 | 37368207 | 37368213 | 7mer-m8 | 37368206 | 37368227 | 147 | -22.33 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000166897.15 | ENST00000402918.7 | ELFN2-201 | hsa-miR-4775 | chr22 | 37369001 | 37369008 | 8mer-1a | 37369001 | 37369023 | 155 | -13.13 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000166897.15 | ENST00000613079.4 | ELFN2-207 | hsa-miR-4775 | chr22 | 37369001 | 37369008 | 8mer-1a | 37369001 | 37369023 | 155 | -13.13 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for ELFN2 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000402918.7 | protein_coding |  |  |
| ENST00000613079.4 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_988968 | ENST00000402918.7 | chr22_37369569_- | 6761 | -3803.20 | -3797.40 | -3809.40 |
| ADediting_988969 | ENST00000402918.7 | chr22_37374134_- | 2196 | -3803.60 | -3797.40 | -3809.40 |
| ADediting_988968 | ENST00000613079.4 | chr22_37369569_- | 6752 | -3793.30 | -3787.50 | -3799.50 |
| ADediting_988969 | ENST00000613079.4 | chr22_37374134_- | 2187 | -3793.70 | -3787.50 | -3799.50 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for ELFN2 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 8.39765446748345e-64 | 0.776743510548555 | 1.81157818922055e-79 | 0.828272732903967 | 0.000522734414427557 | 0.195895308187088 |
| AC | 4.61385896665768e-52 | 0.778410258674844 | 7.38578878624185e-58 | 0.803766634022892 | 6.56069314916695e-05 | 0.249696898444667 |
| PCC | 2.37844702286005e-42 | 0.791909675581568 | 5.03143549921432e-39 | 0.771853573727078 | 0.00117924514441698 | 0.233007275927092 |
| TCX | 8.61858767590586e-08 | 0.420230722686993 | 6.3926870250691e-13 | 0.543830475638509 | 0.0178247102973241 | -0.19323715140319 |
| FP | 4.3063474985077e-09 | 0.422331587438153 | 0.00113632714950572 | 0.241996474507822 | 3.42445373458891e-11 | 0.470507323543377 |
| IFG | 1.00459144492174e-06 | 0.808583883448982 | 1.15013077218156e-07 | 0.843989170007234 | 0.254286527731737 | 0.236863324000402 |
| STG | 2.36153180773771e-09 | 0.595175005287832 | 1.97103067119785e-07 | 0.53150447382741 | 0.0338189897409641 | 0.231862225202171 |
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Relation with AD stages for ELFN2 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| TCX | 0.00080959068224169 | 0.320505131373929 |
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RelatedDrugs for ELFN2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ELFN2 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
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