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Center for Computational Systems Medicine
Soverview

Gene summary

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RNA A-to-I events

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Differntial gene expression between RNA A-to-I edited versus non-edited samples

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Protein coding region RNA A-to-I editings

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The effects of the RNA editing to the miRNA binding sites

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The effects of the RNA editing to the stability of the RNA structures

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Relation with ADAR

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Relation with AD stages

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Related drugs with this gene

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Related diseases with this gene


Gene summary for SCRG1

check button Gene summary
Gene informationGene symbol

SCRG1

Gene ID

11341

Gene namestimulator of chondrogenesis 1
SynonymsSCRG-1
Cytomap

4q34.1

Type of geneprotein-coding
Descriptionscrapie-responsive protein 1scrapie responsive gene 1scrapie-responsive gene 1 protein
Modification date20200313
UniProtAcc

O75711,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for SCRG1

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1116611(173385212, -), ADediting_1116612(173385218, -), ADediting_1116613(173385224, -), ADediting_1116614(173385225, -), ADediting_1116615(173385247, -), ADediting_1116616(173385250, -), ADediting_1116617(173385251, -), ADediting_1116618(173385252, -), ADediting_1116619(173385300, -), ADediting_1116620(173385342, -), ADediting_1116621(173385369, -), ADediting_1116622(173385370, -), ADediting_1116623(173385381, -), ADediting_1116624(173385387, -), ADediting_1116625(173385388, -), ADediting_1116626(173385394, -), ADediting_1116627(173385423, -), ADediting_1116628(173385426, -), ADediting_1116629(173385432, -), ADediting_1116630(173385434, -), ADediting_1116631(173385439, -), ADediting_1116632(173385448, -), ADediting_1116633(173385456, -), ADediting_1116634(173385462, -), ADediting_1116635(173386182, -), ADediting_1116636(173386227, -), ADediting_1116637(173386273, -), ADediting_1116638(173386299, -), ADediting_1116639(173386343, -), ADediting_1116640(173386368, -), ADediting_1116641(173386415, -), ADediting_1116642(173386420, -), ADediting_1116643(173386421, -), ADediting_1116644(173387408, -), ADediting_1116645(173387478, -), ADediting_1116646(173387490, -), ADediting_1116647(173387508, -), ADediting_1116648(173387618, -), ADediting_1116649(173387619, -), ADediting_1116650(173387627, -), ADediting_1116651(173389291, -), ADediting_1116653(173390533, -), ADediting_1116654(173390611, -), ADediting_1116655(173390621, -), ADediting_1116656(173390701, -),

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RNA editing positional annotations for SCRG1 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1116611chr4_173385212_-UTR3
ADediting_1116612chr4_173385218_-UTR3
ADediting_1116613chr4_173385224_-UTR3
ADediting_1116614chr4_173385225_-UTR3
ADediting_1116615chr4_173385247_-UTR3
ADediting_1116616chr4_173385250_-UTR3
ADediting_1116617chr4_173385251_-UTR3
ADediting_1116618chr4_173385252_-UTR3
ADediting_1116619chr4_173385300_-UTR3
ADediting_1116620chr4_173385342_-UTR3
ADediting_1116621chr4_173385369_-UTR3
ADediting_1116622chr4_173385370_-UTR3
ADediting_1116623chr4_173385381_-UTR3
ADediting_1116624chr4_173385387_-UTR3
ADediting_1116625chr4_173385388_-UTR3
ADediting_1116626chr4_173385394_-UTR3
ADediting_1116627chr4_173385423_-UTR3
ADediting_1116628chr4_173385426_-UTR3
ADediting_1116629chr4_173385432_-UTR3
ADediting_1116630chr4_173385434_-UTR3
ADediting_1116631chr4_173385439_-UTR3
ADediting_1116632chr4_173385448_-UTR3
ADediting_1116633chr4_173385456_-UTR3
ADediting_1116634chr4_173385462_-UTR3
ADediting_1116635chr4_173386182_-UTR3
ADediting_1116636chr4_173386227_-UTR3
ADediting_1116637chr4_173386273_-UTR3
ADediting_1116638chr4_173386299_-UTR3
ADediting_1116639chr4_173386343_-UTR3
ADediting_1116640chr4_173386368_-UTR3
ADediting_1116641chr4_173386415_-UTR3
ADediting_1116642chr4_173386420_-UTR3
ADediting_1116643chr4_173386421_-UTR3
ADediting_1116644chr4_173387408_-UTR3
ADediting_1116645chr4_173387478_-UTR3
ADediting_1116646chr4_173387490_-UTR3
ADediting_1116647chr4_173387508_-UTR3
ADediting_1116648chr4_173387618_-UTR3
ADediting_1116649chr4_173387619_-UTR3
ADediting_1116650chr4_173387627_-UTR3
ADediting_1116651chr4_173389291_-intronic
ADediting_1116653chr4_173390533_-intronic
ADediting_1116654chr4_173390611_-intronic
ADediting_1116655chr4_173390621_-intronic
ADediting_1116656chr4_173390701_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1116611chr4_173385212_-SINEAluName=AluSz6
ADediting_1116612chr4_173385218_-SINEAluName=AluSz6
ADediting_1116613chr4_173385224_-SINEAluName=AluSz6
ADediting_1116614chr4_173385225_-SINEAluName=AluSz6
ADediting_1116615chr4_173385247_-SINEAluName=AluSz6
ADediting_1116616chr4_173385250_-SINEAluName=AluSz6
ADediting_1116617chr4_173385251_-SINEAluName=AluSz6
ADediting_1116618chr4_173385252_-SINEAluName=AluSz6
ADediting_1116619chr4_173385300_-SINEAluName=AluSz6
ADediting_1116620chr4_173385342_-SINEAluName=AluSz6
ADediting_1116621chr4_173385369_-SINEAluName=AluSz6
ADediting_1116622chr4_173385370_-SINEAluName=AluSz6
ADediting_1116623chr4_173385381_-SINEAluName=AluSz6
ADediting_1116624chr4_173385387_-SINEAluName=AluSz6
ADediting_1116625chr4_173385388_-SINEAluName=AluSz6
ADediting_1116626chr4_173385394_-SINEAluName=AluSz6
ADediting_1116627chr4_173385423_-SINEAluName=AluSz6
ADediting_1116628chr4_173385426_-SINEAluName=AluSz6
ADediting_1116629chr4_173385432_-SINEAluName=AluSz6
ADediting_1116630chr4_173385434_-SINEAluName=AluSz6
ADediting_1116631chr4_173385439_-SINEAluName=AluSz6
ADediting_1116632chr4_173385448_-SINEAluName=AluSz6
ADediting_1116633chr4_173385456_-SINEAluName=AluSz6
ADediting_1116634chr4_173385462_-SINEAluName=AluSz6
ADediting_1116635chr4_173386182_-SINEAluName=AluY
ADediting_1116636chr4_173386227_-SINEAluName=AluY
ADediting_1116637chr4_173386273_-SINEAluName=AluY
ADediting_1116638chr4_173386299_-SINEAluName=AluY
ADediting_1116639chr4_173386343_-SINEAluName=AluY
ADediting_1116640chr4_173386368_-SINEAluName=AluY
ADediting_1116641chr4_173386415_-SINEAluName=AluY
ADediting_1116642chr4_173386420_-SINEAluName=AluY
ADediting_1116643chr4_173386421_-SINEAluName=AluY
ADediting_1116644chr4_173387408_-SINEAluName=AluJo
ADediting_1116645chr4_173387478_-SINEAluName=AluJo
ADediting_1116646chr4_173387490_-SINEAluName=AluJo
ADediting_1116647chr4_173387508_-SINEAluName=AluJo
ADediting_1116648chr4_173387618_-SINEAluName=AluJo
ADediting_1116649chr4_173387619_-SINEAluName=AluJo
ADediting_1116650chr4_173387627_-SINEAluName=AluJo
ADediting_1116651chr4_173389291_-SINEAluName=AluYf1
ADediting_1116653chr4_173390533_-SINEAluName=AluSq2
ADediting_1116654chr4_173390611_-SINEAluName=AluSq2
ADediting_1116655chr4_173390621_-SINEAluName=AluSq2
ADediting_1116656chr4_173390701_-SINEAluName=AluSq2

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RNA A-to-I editing events in the alternative splicing sites for SCRG1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SCRG1

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for SCRG1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for SCRG1

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1116612chr4_173385218_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-4733-5pchr41733852141733852207mer-m8173385213173385234152-16.58
ADediting_1116613chr4_173385224_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-3189-3pchr41733852231733852297mer-m8173385222173385241141-22.4
ADediting_1116613chr4_173385224_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6813-3pchr41733852221733852287mer-m8173385221173385241140-12.88
ADediting_1116614chr4_173385225_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-326chr41733852231733852297mer-m8173385222173385241140-15.33
ADediting_1116614chr4_173385225_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-330-5pchr41733852231733852297mer-m8173385222173385243140-22.45
ADediting_1116614chr4_173385225_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-4314chr41733852241733852307mer-m8173385223173385240140-18.79
ADediting_1116614chr4_173385225_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-514a-5pchr41733852221733852287mer-m8173385221173385241154-19.31
ADediting_1116615chr4_173385247_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6502-3pchr41733852441733852507mer-m8173385243173385266145-17.05
ADediting_1116617chr4_173385251_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-12119chr41733852501733852567mer-m8173385249173385269149-22.78
ADediting_1116617chr4_173385251_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-3200-5pchr41733852491733852557mer-m8173385248173385271141-14.79
ADediting_1116617chr4_173385251_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-452-3pchr41733852471733852537mer-m8173385246173385267140-11.83
ADediting_1116617chr4_173385251_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-4649-3pchr41733852501733852578mer-1a173385250173385270147-18.76
ADediting_1116618chr4_173385252_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-1298-5pchr41733852471733852537mer-m8173385246173385265150-18.59
ADediting_1116619chr4_173385300_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-3675-3pchr41733852981733853047mer-m8173385297173385320148-12.58
ADediting_1116619chr4_173385300_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-4684-5pchr41733852991733853057mer-m8173385298173385321155-14.81
ADediting_1116620chr4_173385342_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6720-3pchr41733853411733853477mer-m8173385340173385361152-20.49
ADediting_1116621chr4_173385369_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-3929chr41733853661733853727mer-m8173385365173385389151-25.11
ADediting_1116621chr4_173385369_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-4478chr41733853661733853727mer-m8173385365173385382146-19.74
ADediting_1116621chr4_173385369_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-485-5pchr41733853651733853717mer-m8173385364173385385145-16.57
ADediting_1116621chr4_173385369_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6884-5pchr41733853651733853717mer-m8173385364173385385146-19.66
ADediting_1116623chr4_173385381_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-7112-3pchr41733853801733853867mer-m8173385379173385402144-18.52
ADediting_1116624chr4_173385387_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-3622a-3pchr41733853831733853908mer-1a173385383173385405149-18.21
ADediting_1116624chr4_173385387_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-3622b-3pchr41733853831733853908mer-1a173385383173385403147-18.77
ADediting_1116626chr4_173385394_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-1247-3pchr41733853921733853987mer-m8173385391173385413152-24.12
ADediting_1116627chr4_173385423_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6529-3pchr41733854231733854297mer-m8173385422173385444155-15.88
ADediting_1116627chr4_173385423_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6889-3pchr41733854231733854297mer-m8173385422173385443150-16.72
ADediting_1116630chr4_173385434_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-4793-3pchr41733854311733854377mer-m8173385430173385452165-26.03
ADediting_1116630chr4_173385434_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-7703chr41733854321733854387mer-m8173385431173385453170-29.73
ADediting_1116631chr4_173385439_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-1234-3pchr41733854391733854457mer-m8173385438173385459140-16.45
ADediting_1116632chr4_173385448_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-4486chr41733854431733854497mer-m8173385442173385460146-18.47
ADediting_1116634chr4_173385462_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-3130-5pchr41733854601733854667mer-m8173385459173385479147-12.22
ADediting_1116634chr4_173385462_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-4482-5pchr41733854601733854667mer-m8173385459173385479146-12.75
ADediting_1116635chr4_173386182_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-4743-5pchr41733861791733861857mer-m8173386178173386197147-26.03
ADediting_1116639chr4_173386343_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-3188chr41733863391733863457mer-m8173386338173386359151-14.54
ADediting_1116639chr4_173386343_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-412-3pchr41733863431733863497mer-m8173386342173386360151-18.93
ADediting_1116639chr4_173386343_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6754-3pchr41733863431733863497mer-m8173386342173386362146-15.85
ADediting_1116641chr4_173386415_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-371a-3pchr41733864101733864167mer-m8173386409173386431145-17.36
ADediting_1116642chr4_173386420_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-8052chr41733864151733864217mer-1a173386415173386433140-24.15
ADediting_1116643chr4_173386421_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-513a-5pchr41733864201733864267mer-m8173386419173386436144-16.68
ADediting_1116643chr4_173386421_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-638chr41733864151733864217mer-1a173386415173386439159-35.56
ADediting_1116644chr4_173387408_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-593-5pchr41733874031733874108mer-1a173387403173387427156-23.6
ADediting_1116644chr4_173387408_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-767-5pchr41733874051733874117mer-m8173387404173387427150-18.37
ADediting_1116644chr4_173387408_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-9851-3pchr41733874031733874108mer-1a173387403173387423146-20.55
ADediting_1116648chr4_173387618_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-3117-3pchr41733876131733876197mer-m8173387612173387637147-19.95
ADediting_1116648chr4_173387618_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-4759chr41733876131733876208mer-1a173387613173387635147-16.75
ADediting_1116649chr4_173387619_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-513a-5pchr41733876181733876247mer-m8173387617173387634148-18.07

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1116614chr4_173385225_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-887-5pchr41733852241733852318mer-1a173385224173385245150-16.93
ADediting_1116615chr4_173385247_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-1288-5pchr41733852431733852497mer-m8173385242173385264140-13.48
ADediting_1116615chr4_173385247_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-5694chr41733852441733852507mer-m8173385243173385263144-18.01
ADediting_1116615chr4_173385247_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-579-3pchr41733852471733852537mer-m8173385246173385268141-10.12
ADediting_1116615chr4_173385247_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-664b-3pchr41733852471733852537mer-m8173385246173385266142-12.45
ADediting_1116616chr4_173385250_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-579-3pchr41733852471733852537mer-m8173385246173385268141-10.12
ADediting_1116616chr4_173385250_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-664b-3pchr41733852471733852537mer-m8173385246173385266142-12.45
ADediting_1116617chr4_173385251_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-579-3pchr41733852471733852537mer-m8173385246173385268141-10.12
ADediting_1116617chr4_173385251_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-664b-3pchr41733852471733852537mer-m8173385246173385266142-12.45
ADediting_1116618chr4_173385252_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-579-3pchr41733852471733852537mer-m8173385246173385268141-10.12
ADediting_1116618chr4_173385252_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-664b-3pchr41733852471733852537mer-m8173385246173385266142-12.45
ADediting_1116620chr4_173385342_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-33b-3pchr41733853401733853467mer-m8173385339173385359152-18.31
ADediting_1116620chr4_173385342_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-515-3pchr41733853401733853467mer-m8173385339173385360143-14.04
ADediting_1116620chr4_173385342_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-519e-3pchr41733853401733853467mer-m8173385339173385360140-16.03
ADediting_1116620chr4_173385342_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-550a-3-5pchr41733853411733853477mer-m8173385340173385359143-18.47
ADediting_1116620chr4_173385342_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-550a-5pchr41733853411733853477mer-m8173385340173385362143-20.73
ADediting_1116621chr4_173385369_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-377-5pchr41733853651733853717mer-m8173385364173385385140-12.31
ADediting_1116621chr4_173385369_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6086chr41733853651733853717mer-m8173385364173385381151-21.26
ADediting_1116622chr4_173385370_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-377-5pchr41733853651733853717mer-m8173385364173385385140-12.31
ADediting_1116622chr4_173385370_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6086chr41733853651733853717mer-m8173385364173385381151-21.26
ADediting_1116624chr4_173385387_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-3614-5pchr41733853831733853897mer-1a173385383173385406155-25.83
ADediting_1116625chr4_173385388_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-3614-5pchr41733853831733853897mer-1a173385383173385406155-25.83
ADediting_1116626chr4_173385394_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-3689a-3pchr41733853941733854007mer-m8173385393173385413146-20.25
ADediting_1116626chr4_173385394_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-3689b-3pchr41733853941733854007mer-m8173385393173385413154-23.63
ADediting_1116626chr4_173385394_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-3689cchr41733853941733854007mer-m8173385393173385413154-23.63
ADediting_1116626chr4_173385394_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-490-3pchr41733853901733853967mer-m8173385389173385411146-17.33
ADediting_1116626chr4_173385394_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6779-5pchr41733853941733854007mer-m8173385393173385411152-23.44
ADediting_1116626chr4_173385394_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6780a-5pchr41733853941733854007mer-m8173385393173385417147-24.54
ADediting_1116628chr4_173385426_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-1227-3pchr41733854241733854318mer-1a173385424173385443147-14.44
ADediting_1116629chr4_173385432_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-4252chr41733854261733854338mer-1a173385426173385445145-16.28
ADediting_1116631chr4_173385439_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-3176chr41733854371733854448mer-1a173385437173385455155-25.03
ADediting_1116631chr4_173385439_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-3922-3pchr41733854371733854448mer-1a173385437173385456146-18.98
ADediting_1116632chr4_173385448_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-1262chr41733854441733854507mer-m8173385443173385465144-15.28
ADediting_1116632chr4_173385448_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6736-5pchr41733854441733854507mer-m8173385443173385463143-20.94
ADediting_1116633chr4_173385456_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-5586-3pchr41733854521733854587mer-m8173385451173385472152-16.78
ADediting_1116633chr4_173385456_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6864-3pchr41733854561733854627mer-m8173385455173385475141-14.57
ADediting_1116633chr4_173385456_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-759chr41733854511733854577mer-m8173385450173385472151-12.38
ADediting_1116635chr4_173386182_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-3652chr41733861791733861857mer-m8173386178173386197148-20.61
ADediting_1116636chr4_173386227_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6742-3pchr41733862241733862318mer-1a173386224173386245153-20.13
ADediting_1116636chr4_173386227_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6783-3pchr41733862241733862307mer-m8173386223173386243151-19.27
ADediting_1116637chr4_173386273_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-520g-5pchr41733862721733862787mer-m8173386271173386291142-16.4
ADediting_1116637chr4_173386273_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6503-3pchr41733862691733862757mer-m8173386268173386289145-25.46
ADediting_1116637chr4_173386273_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6866-5pchr41733862731733862797mer-m8173386272173386294140-17.06
ADediting_1116637chr4_173386273_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-8052chr41733862671733862737mer-1a173386267173386287141-22.31
ADediting_1116638chr4_173386299_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-4735-5pchr41733862981733863047mer-m8173386297173386318140-4.28
ADediting_1116641chr4_173386415_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-5089-5pchr41733864151733864217mer-m8173386414173386436148-14.13
ADediting_1116641chr4_173386415_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-512-3pchr41733864101733864167mer-m8173386409173386430149-15.51
ADediting_1116641chr4_173386415_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6506-5pchr41733864141733864207mer-m8173386413173386435144-13.78
ADediting_1116642chr4_173386420_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-10399-5pchr41733864191733864257mer-m8173386418173386439144-11.2
ADediting_1116642chr4_173386420_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-5089-5pchr41733864151733864217mer-m8173386414173386436148-14.13
ADediting_1116642chr4_173386420_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6504-3pchr41733864191733864257mer-m8173386418173386439148-14.35
ADediting_1116643chr4_173386421_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-10399-5pchr41733864191733864257mer-m8173386418173386439144-11.2
ADediting_1116643chr4_173386421_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6504-3pchr41733864191733864257mer-m8173386418173386439148-14.35
ADediting_1116643chr4_173386421_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-7151-3pchr41733864201733864278mer-1a173386420173386440144-16.51
ADediting_1116644chr4_173387408_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-4642chr41733874031733874097mer-m8173387402173387423151-19.85
ADediting_1116646chr4_173387490_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-552-3pchr41733874841733874918mer-1a173387484173387504144-14.26
ADediting_1116646chr4_173387490_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-764chr41733874861733874927mer-m8173387485173387505141-18.03
ADediting_1116647chr4_173387508_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-4735-5pchr41733875071733875137mer-m8173387506173387527145-4.28
ADediting_1116647chr4_173387508_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-4775chr41733875081733875147mer-m8173387507173387528150-5.25
ADediting_1116648chr4_173387618_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-10399-5pchr41733876171733876237mer-m8173387616173387640155-15.28
ADediting_1116648chr4_173387618_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6504-3pchr41733876171733876237mer-m8173387616173387637148-9.48
ADediting_1116649chr4_173387619_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-10399-5pchr41733876171733876237mer-m8173387616173387640155-15.28
ADediting_1116649chr4_173387619_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-6504-3pchr41733876171733876237mer-m8173387616173387637148-9.48
ADediting_1116649chr4_173387619_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-7151-3pchr41733876181733876258mer-1a173387618173387638140-13.01

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1097295chr3_85385762_+ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-5688chr41733850431733850497mer-m8173385042173385062152-11.1
ADediting_843620chr2_207754818_+ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-4775chr41733872211733872288mer-1a173387221173387242148-10.39

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1556067chr19_40282625_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-641chr41733864641733864707mer-1a173386464173386488149-17.07
ADediting_1631458chr19_40282624_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-641chr41733864641733864707mer-1a173386464173386488149-17.07
ADediting_291761chr11_93733708_-ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-1304-3pchr41733850221733850287mer-m8173385021173385042148-12.94
ADediting_843620chr2_207754818_+ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-4775chr41733875081733875147mer-m8173387507173387528150-5.25
ADediting_843620chr2_207754818_+ENSG00000164106.8ENST00000296506.8SCRG1-201hsa-miR-4775chr41733878711733878788mer-1a173387871173387893151-7.36

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for SCRG1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000296506.8protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_1116611ENST00000296506.8chr4_173385212_-3489-1197.74-1197.74-1254.00
ADediting_1116612ENST00000296506.8chr4_173385218_-3483-1197.44-1197.74-1254.00
ADediting_1116613ENST00000296506.8chr4_173385224_-3477-1197.34-1197.74-1254.00
ADediting_1116614ENST00000296506.8chr4_173385225_-3476-1197.84-1197.74-1254.00
ADediting_1116615ENST00000296506.8chr4_173385247_-3454-1197.14-1197.74-1254.00
ADediting_1116616ENST00000296506.8chr4_173385250_-3451-1203.94-1197.74-1254.00
ADediting_1116617ENST00000296506.8chr4_173385251_-3450-1197.44-1197.74-1254.00
ADediting_1116618ENST00000296506.8chr4_173385252_-3449-1197.44-1197.74-1254.00
ADediting_1116619ENST00000296506.8chr4_173385300_-3401-1204.14-1197.74-1254.00
ADediting_1116620ENST00000296506.8chr4_173385342_-3359-1203.14-1197.74-1254.00
ADediting_1116621ENST00000296506.8chr4_173385369_-3332-1204.44-1197.74-1254.00
ADediting_1116622ENST00000296506.8chr4_173385370_-3331-1197.04-1197.74-1254.00
ADediting_1116623ENST00000296506.8chr4_173385381_-3320-1197.74-1197.74-1254.00
ADediting_1116624ENST00000296506.8chr4_173385387_-3314-1200.34-1197.74-1254.00
ADediting_1116625ENST00000296506.8chr4_173385388_-3313-1198.44-1197.74-1254.00
ADediting_1116626ENST00000296506.8chr4_173385394_-3307-1201.64-1197.74-1254.00
ADediting_1116627ENST00000296506.8chr4_173385423_-3278-1197.94-1197.74-1254.00
ADediting_1116628ENST00000296506.8chr4_173385426_-3275-1197.34-1197.74-1254.00
ADediting_1116629ENST00000296506.8chr4_173385432_-3269-1197.04-1197.74-1254.00
ADediting_1116630ENST00000296506.8chr4_173385434_-3267-1204.44-1197.74-1254.00
ADediting_1116631ENST00000296506.8chr4_173385439_-3262-1201.64-1197.74-1254.00
ADediting_1116632ENST00000296506.8chr4_173385448_-3253-1203.14-1197.74-1254.00
ADediting_1116633ENST00000296506.8chr4_173385456_-3245-1197.34-1197.74-1254.00
ADediting_1116634ENST00000296506.8chr4_173385462_-3239-1196.84-1197.74-1254.00
ADediting_1116635ENST00000296506.8chr4_173386182_-2519-1201.64-1197.74-1254.00
ADediting_1116636ENST00000296506.8chr4_173386227_-2474-1201.64-1197.74-1254.00
ADediting_1116637ENST00000296506.8chr4_173386273_-2428-1197.44-1197.74-1254.00
ADediting_1116638ENST00000296506.8chr4_173386299_-2402-1197.44-1197.74-1254.00
ADediting_1116639ENST00000296506.8chr4_173386343_-2358-1197.74-1197.74-1254.00
ADediting_1116640ENST00000296506.8chr4_173386368_-2333-1197.74-1197.74-1254.00
ADediting_1116641ENST00000296506.8chr4_173386415_-2286-1196.94-1197.74-1254.00
ADediting_1116642ENST00000296506.8chr4_173386420_-2281-1199.84-1197.74-1254.00
ADediting_1116643ENST00000296506.8chr4_173386421_-2280-1197.74-1197.74-1254.00
ADediting_1116644ENST00000296506.8chr4_173387408_-1293-1199.04-1197.74-1254.00
ADediting_1116645ENST00000296506.8chr4_173387478_-1223-1197.04-1197.74-1254.00
ADediting_1116646ENST00000296506.8chr4_173387490_-1211-1200.84-1197.74-1254.00
ADediting_1116647ENST00000296506.8chr4_173387508_-1193-1197.64-1197.74-1254.00
ADediting_1116648ENST00000296506.8chr4_173387618_-1083-1197.74-1197.74-1254.00
ADediting_1116649ENST00000296506.8chr4_173387619_-1082-1197.84-1197.74-1254.00
ADediting_1116650ENST00000296506.8chr4_173387627_-1074-1198.04-1197.74-1254.00

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for SCRG1

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
ACADediting_1116612chr4_173385218_-0.00106941377030950.2057273160352450.1014223468014480.1038361787784674.10135203376366e-080.338397256492714
ACADediting_1116616chr4_173385250_-2.32027986419039e-050.2641841877718950.002107122215807950.1935885964511329.0852051160612e-080.330123853870208
FPADediting_1116616chr4_173385250_-0.3212811556631220.07476332186114320.4860101588594010.05255166932579041.63443530226839e-070.380337339428832
ACADediting_1116617chr4_173385251_-0.0002071198141204330.2325911696765970.0175021499898460.1501699861515757.04393570267313e-080.33279768090229
ACADediting_1116618chr4_173385252_-1.61914093106142e-060.2978999624571220.005956342972101950.1734849098143451.21580193620972e-120.429458697757329
ACADediting_1116620chr4_173385342_-0.2700431539507120.07002277914449160.448329499179746-0.04816651230883796.98268425661775e-110.397315005804907
DLPFCADediting_1116621chr4_173385369_-0.1124379154144360.09033480627671770.78117524979896-0.01584028833980074.04940570397927e-080.305486856626189
DLPFCADediting_1116626chr4_173385394_-0.8874197416695260.008073112561882470.0617334503582835-0.1062356478066354.4524352605926e-080.304597394349573
DLPFCADediting_1116630chr4_173385434_-0.2295070312469190.0684444192764670.294653751328041-0.05970862286749144.71183125532963e-150.425368280937113
DLPFCADediting_1116631chr4_173385439_-0.7249413925806130.02006348619490250.431708659940621-0.04481580249273454.3827099795085e-120.379959432282477
DLPFCADediting_1116635chr4_173386182_-0.1510020627121270.08175305751668770.6248555542296510.02787944908240491.73224372561117e-090.333484453628611
DLPFCADediting_1116639chr4_173386343_-0.888507025484612-0.007994630774532230.0614258211456097-0.1063607440049914.16559469778044e-140.411625650741498
TCXADediting_1116649chr4_173387619_-0.1433543756309660.1200588874215610.104265117773946-0.1331639680247880.0001434782799889840.305538496251173

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.01853378140323e-120.3902532234846561.70060995906651e-060.2679280656672220.003244107896903730.166687891500598
AC2.47631424806744e-290.6324347578511659.04613581795103e-150.4642894594822991.20997263889297e-300.643679454344803
PCC2.20727951129375e-060.3347642825325642.67970702295602e-050.2988265854196110.0001422346213382330.27184823796735
CER2.71269983332669e-050.335453949751760.3635158789102990.07471516166783446.1868422767875e-070.393773550113126
TCX0.0007031976544429670.2736451287750150.32313157210603-0.08121944259219076.20070528853694e-060.359597743961256
FP3.99666651645472e-110.4690783166887271.52941807049483e-110.4778565292074490.1921069224369490.0982222037706714
IFG0.0332843748416310.4269637287157910.2435160161326410.2421543488944250.4958685683936390.142811619216046
PG2.85532565993223e-370.7667949642554291.02812331145071e-160.5595272194237430.7731264213754630.021279345959976
STG3.90887090327957e-090.5885694906497498.70892434683774e-080.5443075327025170.788280623380558-0.0297396857904657

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Relation with AD stages for SCRG1

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
TCXADediting_1116646chr4_173387490_-0.0008169901611369770.320276708049278

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
TCX1.37728382794737e-050.408528664295608

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RelatedDrugs for SCRG1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SCRG1

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource