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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

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Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for SPACA9

check button Gene summary
Gene informationGene symbol

SPACA9

Gene ID

11092

Gene namesperm acrosome associated 9
SynonymsC9orf9|Mast
Cytomap

9q34.13

Type of geneprotein-coding
Descriptionsperm acrosome-associated protein 9Rsb66 homolog
Modification date20200313
UniProtAcc

Q96E40,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for SPACA9

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1453960(132881086, +), ADediting_1453961(132881216, +), ADediting_1453962(132881346, +), ADediting_1453963(132881361, +), ADediting_1453964(132881383, +), ADediting_1453965(132881388, +), ADediting_1453966(132881431, +), ADediting_1453967(132885433, +), ADediting_1453968(132886912, +), ADediting_1453969(132887066, +), ADediting_1453970(132888848, +), ADediting_1453971(132888872, +), ADediting_1453972(132888894, +), ADediting_1453973(132888897, +), ADediting_1453974(132888907, +), ADediting_1453975(132888974, +), ADediting_1453976(132888978, +), ADediting_1453977(132888989, +), ADediting_1453978(132889031, +), ADediting_1453979(132889032, +), ADediting_1453980(132889044, +), ADediting_1453981(132889204, +), ADediting_1453982(132889438, +), ADediting_1453983(132889468, +), ADediting_1453984(132889493, +), ADediting_1453985(132889505, +), ADediting_1453986(132889506, +), ADediting_1453987(132889523, +), ADediting_1453988(132889535, +), ADediting_1453989(132889545, +), ADediting_1453990(132889595, +), ADediting_1453991(132889598, +), ADediting_1453992(132889658, +), ADediting_1453993(132889676, +), ADediting_1453994(132889677, +), ADediting_1453995(132889689, +),

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RNA editing positional annotations for SPACA9 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1453960chr9_132881086_+intronic
ADediting_1453961chr9_132881216_+intronic
ADediting_1453962chr9_132881346_+intronic
ADediting_1453963chr9_132881361_+intronic
ADediting_1453964chr9_132881383_+intronic
ADediting_1453965chr9_132881388_+intronic
ADediting_1453966chr9_132881431_+intronic
ADediting_1453967chr9_132885433_+intronic
ADediting_1453968chr9_132886912_+intronic
ADediting_1453969chr9_132887066_+intronic
ADediting_1453970chr9_132888848_+UTR3
ADediting_1453971chr9_132888872_+UTR3
ADediting_1453972chr9_132888894_+UTR3
ADediting_1453973chr9_132888897_+UTR3
ADediting_1453974chr9_132888907_+UTR3
ADediting_1453975chr9_132888974_+UTR3
ADediting_1453976chr9_132888978_+UTR3
ADediting_1453977chr9_132888989_+UTR3
ADediting_1453978chr9_132889031_+UTR3
ADediting_1453979chr9_132889032_+UTR3
ADediting_1453980chr9_132889044_+UTR3
ADediting_1453981chr9_132889204_+UTR3
ADediting_1453982chr9_132889438_+UTR3
ADediting_1453983chr9_132889468_+UTR3
ADediting_1453984chr9_132889493_+UTR3
ADediting_1453985chr9_132889505_+UTR3
ADediting_1453986chr9_132889506_+UTR3
ADediting_1453987chr9_132889523_+UTR3
ADediting_1453988chr9_132889535_+UTR3
ADediting_1453989chr9_132889545_+UTR3
ADediting_1453990chr9_132889595_+UTR3
ADediting_1453991chr9_132889598_+UTR3
ADediting_1453992chr9_132889658_+UTR3
ADediting_1453993chr9_132889676_+UTR3
ADediting_1453994chr9_132889677_+UTR3
ADediting_1453995chr9_132889689_+UTR3

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1453960chr9_132881086_+SINEAluName=AluY
ADediting_1453961chr9_132881216_+SINEAluName=FLAM_C
ADediting_1453962chr9_132881346_+SINEAluName=AluJb
ADediting_1453963chr9_132881361_+SINEAluName=AluJb
ADediting_1453964chr9_132881383_+SINEAluName=AluJb
ADediting_1453965chr9_132881388_+SINEAluName=AluJb
ADediting_1453966chr9_132881431_+SINEAluName=AluJb
ADediting_1453967chr9_132885433_+SINEAluName=AluSx
ADediting_1453968chr9_132886912_+SINEAluName=AluSz
ADediting_1453969chr9_132887066_+SINEAluName=AluSz
ADediting_1453970chr9_132888848_+SINEAluName=AluYf1
ADediting_1453971chr9_132888872_+SINEAluName=AluYf1
ADediting_1453972chr9_132888894_+SINEAluName=AluYf1
ADediting_1453973chr9_132888897_+SINEAluName=AluYf1
ADediting_1453974chr9_132888907_+SINEAluName=AluYf1
ADediting_1453975chr9_132888974_+SINEAluName=AluYf1
ADediting_1453976chr9_132888978_+SINEAluName=AluYf1
ADediting_1453977chr9_132888989_+SINEAluName=AluYf1
ADediting_1453978chr9_132889031_+SINEAluName=AluYf1
ADediting_1453979chr9_132889032_+SINEAluName=AluYf1
ADediting_1453980chr9_132889044_+SINEAluName=AluYf1
ADediting_1453982chr9_132889438_+SINEAluName=AluSx1
ADediting_1453983chr9_132889468_+SINEAluName=AluSx1
ADediting_1453984chr9_132889493_+SINEAluName=AluSx1
ADediting_1453985chr9_132889505_+SINEAluName=AluSx1
ADediting_1453986chr9_132889506_+SINEAluName=AluSx1
ADediting_1453987chr9_132889523_+SINEAluName=AluSx1
ADediting_1453988chr9_132889535_+SINEAluName=AluSx1
ADediting_1453989chr9_132889545_+SINEAluName=AluSx1
ADediting_1453990chr9_132889595_+SINEAluName=AluSx1
ADediting_1453991chr9_132889598_+SINEAluName=AluSx1
ADediting_1453992chr9_132889658_+SINEAluName=AluSx1
ADediting_1453993chr9_132889676_+SINEAluName=AluSx1
ADediting_1453994chr9_132889677_+SINEAluName=AluSx1
ADediting_1453995chr9_132889689_+SINEAluName=AluSx1

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RNA A-to-I editing events in the alternative splicing sites for SPACA9

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SPACA9

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for SPACA9

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for SPACA9

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1453970chr9_132888848_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-17-3pchr91328888411328888477mer-m8132888827132888848150-18.77
ADediting_1453970chr9_132888848_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-485-5pchr91328888451328888517mer-m8132888832132888852153-18.27
ADediting_1453970chr9_132888848_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-6884-5pchr91328888451328888517mer-m8132888829132888852154-23.9
ADediting_1453970chr9_132888848_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-17-3pchr91328888411328888477mer-m8132888827132888848150-18.77
ADediting_1453970chr9_132888848_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-485-5pchr91328888451328888517mer-m8132888832132888852153-18.27
ADediting_1453970chr9_132888848_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-6884-5pchr91328888451328888517mer-m8132888829132888852154-23.9
ADediting_1453973chr9_132888897_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-3614-5pchr91328888901328888967mer-m8132888874132888897152-25.27
ADediting_1453973chr9_132888897_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-4691-3pchr91328888941328889007mer-m8132888874132888901150-26.36
ADediting_1453973chr9_132888897_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-3614-5pchr91328888901328888967mer-m8132888874132888897152-25.27
ADediting_1453973chr9_132888897_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-4691-3pchr91328888941328889007mer-m8132888874132888901150-26.36
ADediting_1453974chr9_132888907_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-17-3pchr91328889031328889097mer-m8132888888132888910158-20.42
ADediting_1453974chr9_132888907_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-17-3pchr91328889031328889097mer-m8132888888132888910158-20.42
ADediting_1453975chr9_132888974_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-3190-5pchr91328889721328889787mer-m8132888960132888979147-18.34
ADediting_1453975chr9_132888974_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-548schr91328889711328889777mer-m8132888957132888978143-12
ADediting_1453975chr9_132888974_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-3190-5pchr91328889721328889787mer-m8132888960132888979147-18.34
ADediting_1453975chr9_132888974_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-548schr91328889711328889777mer-m8132888957132888978143-12
ADediting_1453978chr9_132889031_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-3192-5pchr91328890241328890318mer-1a132889009132889031158-30.26
ADediting_1453978chr9_132889031_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-326chr91328890261328890327mer-m8132889014132889033140-14.32
ADediting_1453978chr9_132889031_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-330-5pchr91328890261328890327mer-m8132889012132889033140-20.08
ADediting_1453978chr9_132889031_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-4314chr91328890251328890317mer-m8132889015132889032140-19.27
ADediting_1453978chr9_132889031_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-514a-5pchr91328890271328890337mer-m8132889014132889034161-25.3
ADediting_1453978chr9_132889031_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-3192-5pchr91328890241328890318mer-1a132889009132889031158-30.26
ADediting_1453978chr9_132889031_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-326chr91328890261328890327mer-m8132889014132889033140-14.32
ADediting_1453978chr9_132889031_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-330-5pchr91328890261328890327mer-m8132889012132889033140-20.08
ADediting_1453978chr9_132889031_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-4314chr91328890251328890317mer-m8132889015132889032140-19.27
ADediting_1453978chr9_132889031_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-514a-5pchr91328890271328890337mer-m8132889014132889034161-25.3
ADediting_1453979chr9_132889032_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-3189-3pchr91328890261328890327mer-m8132889011132889033145-22.44
ADediting_1453979chr9_132889032_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-6813-3pchr91328890271328890337mer-m8132889014132889034140-12.07
ADediting_1453979chr9_132889032_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-3189-3pchr91328890261328890327mer-m8132889011132889033145-22.44
ADediting_1453979chr9_132889032_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-6813-3pchr91328890271328890337mer-m8132889014132889034140-12.07
ADediting_1453981chr9_132889204_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-125a-3pchr91328891971328892037mer-m8132889182132889204152-21.32
ADediting_1453981chr9_132889204_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-4726-3pchr91328891991328892057mer-m8132889182132889206141-22.41
ADediting_1453981chr9_132889204_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-711chr91328892021328892087mer-m8132889187132889209158-27.18
ADediting_1453981chr9_132889204_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-125a-3pchr91328891971328892037mer-m8132889182132889204152-21.32
ADediting_1453981chr9_132889204_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-4726-3pchr91328891991328892057mer-m8132889182132889206141-22.41
ADediting_1453981chr9_132889204_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-711chr91328892021328892087mer-m8132889187132889209158-27.18
ADediting_1453984chr9_132889493_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-25-5pchr91328894881328894947mer-m8132889476132889495143-19.97
ADediting_1453984chr9_132889493_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-658chr91328894871328894937mer-m8132889468132889494153-29.56
ADediting_1453984chr9_132889493_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-25-5pchr91328894881328894947mer-m8132889476132889495143-19.97
ADediting_1453984chr9_132889493_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-658chr91328894871328894937mer-m8132889468132889494153-29.56
ADediting_1453986chr9_132889506_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-6078chr91328895021328895098mer-1a132889491132889509149-21.32
ADediting_1453986chr9_132889506_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-6078chr91328895021328895098mer-1a132889491132889509149-21.32
ADediting_1453987chr9_132889523_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-6089chr91328895211328895277mer-m8132889505132889528164-39.99
ADediting_1453987chr9_132889523_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-6089chr91328895211328895277mer-m8132889505132889528164-39.99
ADediting_1453988chr9_132889535_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-4691-3pchr91328895321328895387mer-m8132889512132889539150-26.36
ADediting_1453988chr9_132889535_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-4691-3pchr91328895321328895387mer-m8132889512132889539150-26.36
ADediting_1453990chr9_132889595_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-3613-3pchr91328895881328895947mer-m8132889572132889595144-3.57
ADediting_1453990chr9_132889595_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-3613-3pchr91328895881328895947mer-m8132889572132889595144-3.57
ADediting_1453992chr9_132889658_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-4767chr91328896561328896627mer-m8132889641132889663146-21.37
ADediting_1453992chr9_132889658_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-4767chr91328896561328896627mer-m8132889641132889663146-21.37
ADediting_1453993chr9_132889676_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-326chr91328896711328896777mer-m8132889659132889678140-15.12
ADediting_1453993chr9_132889676_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-330-5pchr91328896711328896777mer-m8132889657132889678140-21.22
ADediting_1453993chr9_132889676_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-4314chr91328896701328896767mer-m8132889660132889677140-21.17
ADediting_1453993chr9_132889676_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-514a-5pchr91328896721328896787mer-m8132889656132889679146-20.07
ADediting_1453993chr9_132889676_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-326chr91328896711328896777mer-m8132889659132889678140-15.12
ADediting_1453993chr9_132889676_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-330-5pchr91328896711328896777mer-m8132889657132889678140-21.22
ADediting_1453993chr9_132889676_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-4314chr91328896701328896767mer-m8132889660132889677140-21.17
ADediting_1453993chr9_132889676_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-514a-5pchr91328896721328896787mer-m8132889656132889679146-20.07
ADediting_1453994chr9_132889677_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-3189-3pchr91328896711328896777mer-m8132889655132889678153-24.71
ADediting_1453994chr9_132889677_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-6813-3pchr91328896721328896787mer-m8132889659132889679140-12.55
ADediting_1453994chr9_132889677_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-3189-3pchr91328896711328896777mer-m8132889655132889678153-24.71
ADediting_1453994chr9_132889677_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-6813-3pchr91328896721328896787mer-m8132889659132889679140-12.55

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1453970chr9_132888848_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-377-5pchr91328888451328888517mer-m8132888830132888852149-17.66
ADediting_1453970chr9_132888848_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-6086chr91328888451328888517mer-m8132888833132888852150-23.99
ADediting_1453970chr9_132888848_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-6516-5pchr91328888411328888477mer-m8132888826132888848148-17.04
ADediting_1453970chr9_132888848_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-377-5pchr91328888451328888517mer-m8132888830132888852149-17.66
ADediting_1453970chr9_132888848_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-6086chr91328888451328888517mer-m8132888833132888852150-23.99
ADediting_1453970chr9_132888848_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-6516-5pchr91328888411328888477mer-m8132888826132888848148-17.04
ADediting_1453972chr9_132888894_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-12126chr91328888891328888968mer-1a132888873132888896147-13.23
ADediting_1453972chr9_132888894_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-887-5pchr91328888871328888937mer-m8132888875132888894143-19.73
ADediting_1453972chr9_132888894_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-12126chr91328888891328888968mer-1a132888873132888896147-13.23
ADediting_1453972chr9_132888894_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-887-5pchr91328888871328888937mer-m8132888875132888894143-19.73
ADediting_1453973chr9_132888897_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-5690chr91328888941328889007mer-m8132888881132888901145-16.74
ADediting_1453973chr9_132888897_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-5690chr91328888941328889007mer-m8132888881132888901145-16.74
ADediting_1453975chr9_132888974_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-4794chr91328889721328889787mer-m8132888957132888979150-17.77
ADediting_1453975chr9_132888974_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-664a-5pchr91328889721328889787mer-m8132888952132888979146-18.97
ADediting_1453975chr9_132888974_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-4794chr91328889721328889787mer-m8132888957132888979150-17.77
ADediting_1453975chr9_132888974_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-664a-5pchr91328889721328889787mer-m8132888952132888979146-18.97
ADediting_1453976chr9_132888978_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-4793-5pchr91328889761328889827mer-m8132888960132888983154-18.88
ADediting_1453976chr9_132888978_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-4794chr91328889721328889787mer-m8132888957132888979150-17.77
ADediting_1453976chr9_132888978_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-664a-5pchr91328889721328889787mer-m8132888952132888979146-18.97
ADediting_1453976chr9_132888978_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-4793-5pchr91328889761328889827mer-m8132888960132888983154-18.88
ADediting_1453976chr9_132888978_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-4794chr91328889721328889787mer-m8132888957132888979150-17.77
ADediting_1453976chr9_132888978_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-664a-5pchr91328889721328889787mer-m8132888952132888979146-18.97
ADediting_1453977chr9_132888989_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-5186chr91328889871328889937mer-m8132888974132888994147-15.89
ADediting_1453977chr9_132888989_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-5186chr91328889871328889937mer-m8132888974132888994147-15.89
ADediting_1453982chr9_132889438_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-5586-3pchr91328894351328894417mer-m8132889421132889442148-15.42
ADediting_1453982chr9_132889438_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-759chr91328894361328894427mer-m8132889421132889443155-16.3
ADediting_1453982chr9_132889438_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-5586-3pchr91328894351328894417mer-m8132889421132889442148-15.42
ADediting_1453982chr9_132889438_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-759chr91328894361328894427mer-m8132889421132889443155-16.3
ADediting_1453983chr9_132889468_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-1227-3pchr91328894621328894687mer-m8132889450132889469148-22.88
ADediting_1453983chr9_132889468_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-1227-3pchr91328894621328894687mer-m8132889450132889469148-22.88
ADediting_1453984chr9_132889493_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-3689dchr91328894911328894988mer-1a132889478132889498146-14.69
ADediting_1453984chr9_132889493_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-6851-5pchr91328894911328894988mer-1a132889472132889498155-29.5
ADediting_1453984chr9_132889493_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-7847-3pchr91328894871328894937mer-m8132889472132889494146-19.07
ADediting_1453984chr9_132889493_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-3689dchr91328894911328894988mer-1a132889478132889498146-14.69
ADediting_1453984chr9_132889493_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-6851-5pchr91328894911328894988mer-1a132889472132889498155-29.5
ADediting_1453984chr9_132889493_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-7847-3pchr91328894871328894937mer-m8132889472132889494146-19.07
ADediting_1453987chr9_132889523_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-4478chr91328895201328895267mer-m8132889512132889527149-25.05
ADediting_1453987chr9_132889523_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-4649-3pchr91328895171328895237mer-m8132889504132889524140-14.11
ADediting_1453987chr9_132889523_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-7160-5pchr91328895181328895247mer-m8132889505132889525146-20.4
ADediting_1453987chr9_132889523_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-4478chr91328895201328895267mer-m8132889512132889527149-25.05
ADediting_1453987chr9_132889523_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-4649-3pchr91328895171328895237mer-m8132889504132889524140-14.11
ADediting_1453987chr9_132889523_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-7160-5pchr91328895181328895247mer-m8132889505132889525146-20.4
ADediting_1453988chr9_132889535_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-5690chr91328895321328895387mer-m8132889519132889539145-17.72
ADediting_1453988chr9_132889535_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-5690chr91328895321328895387mer-m8132889519132889539145-17.72
ADediting_1453991chr9_132889598_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-4684-5pchr91328895951328896017mer-m8132889581132889602151-12.03
ADediting_1453991chr9_132889598_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-4684-5pchr91328895951328896017mer-m8132889581132889602151-12.03
ADediting_1453992chr9_132889658_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-363-5pchr91328896541328896607mer-m8132889641132889661154-24.88
ADediting_1453992chr9_132889658_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-4800-5pchr91328896521328896587mer-m8132889634132889659147-23.92
ADediting_1453992chr9_132889658_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-6745chr91328896541328896607mer-m8132889637132889661153-27.18
ADediting_1453992chr9_132889658_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-8071chr91328896531328896597mer-m8132889641132889660154-22.65
ADediting_1453992chr9_132889658_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-363-5pchr91328896541328896607mer-m8132889641132889661154-24.88
ADediting_1453992chr9_132889658_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-4800-5pchr91328896521328896587mer-m8132889634132889659147-23.92
ADediting_1453992chr9_132889658_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-6745chr91328896541328896607mer-m8132889637132889661153-27.18
ADediting_1453992chr9_132889658_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-8071chr91328896531328896597mer-m8132889641132889660154-22.65
ADediting_1453993chr9_132889676_+ENSG00000165698.16ENST00000356311.10SPACA9-202hsa-miR-887-5pchr91328896691328896768mer-1a132889656132889676147-13.82
ADediting_1453993chr9_132889676_+ENSG00000165698.16ENST00000372136.7SPACA9-203hsa-miR-887-5pchr91328896691328896768mer-1a132889656132889676147-13.82

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for SPACA9

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000372136.7protein_codingSoverviewSoverview
ENST00000356311.10protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_1453970ENST00000372136.7chr9_132888848_+1353-960.90-960.90-998.80
ADediting_1453971ENST00000372136.7chr9_132888872_+1377-961.90-960.90-998.80
ADediting_1453972ENST00000372136.7chr9_132888894_+1399-964.50-960.90-998.80
ADediting_1453973ENST00000372136.7chr9_132888897_+1402-964.20-960.90-998.80
ADediting_1453974ENST00000372136.7chr9_132888907_+1412-964.80-960.90-998.80
ADediting_1453975ENST00000372136.7chr9_132888974_+1479-963.70-960.90-998.80
ADediting_1453976ENST00000372136.7chr9_132888978_+1483-960.20-960.90-998.80
ADediting_1453977ENST00000372136.7chr9_132888989_+1494-960.90-960.90-998.80
ADediting_1453978ENST00000372136.7chr9_132889031_+1536-963.60-960.90-998.80
ADediting_1453979ENST00000372136.7chr9_132889032_+1537-964.20-960.90-998.80
ADediting_1453980ENST00000372136.7chr9_132889044_+1549-961.10-960.90-998.80
ADediting_1453981ENST00000372136.7chr9_132889204_+1709-967.50-960.90-998.80
ADediting_1453982ENST00000372136.7chr9_132889438_+1943-962.60-960.90-998.80
ADediting_1453983ENST00000372136.7chr9_132889468_+1973-961.80-960.90-998.80
ADediting_1453984ENST00000372136.7chr9_132889493_+1998-962.40-960.90-998.80
ADediting_1453985ENST00000372136.7chr9_132889505_+2010-966.60-960.90-998.80
ADediting_1453986ENST00000372136.7chr9_132889506_+2011-966.90-960.90-998.80
ADediting_1453987ENST00000372136.7chr9_132889523_+2028-963.10-960.90-998.80
ADediting_1453988ENST00000372136.7chr9_132889535_+2040-962.70-960.90-998.80
ADediting_1453989ENST00000372136.7chr9_132889545_+2050-965.70-960.90-998.80
ADediting_1453990ENST00000372136.7chr9_132889595_+2100-963.60-960.90-998.80
ADediting_1453991ENST00000372136.7chr9_132889598_+2103-961.50-960.90-998.80
ADediting_1453992ENST00000372136.7chr9_132889658_+2163-961.20-960.90-998.80
ADediting_1453993ENST00000372136.7chr9_132889676_+2181-963.60-960.90-998.80
ADediting_1453994ENST00000372136.7chr9_132889677_+2182-963.20-960.90-998.80
ADediting_1453995ENST00000372136.7chr9_132889689_+2194-960.90-960.90-998.80
ADediting_1453970ENST00000356311.10chr9_132888848_+1060-803.80-803.80-842.00
ADediting_1453971ENST00000356311.10chr9_132888872_+1084-804.70-803.80-842.00
ADediting_1453972ENST00000356311.10chr9_132888894_+1106-807.30-803.80-842.00
ADediting_1453973ENST00000356311.10chr9_132888897_+1109-806.90-803.80-842.00
ADediting_1453974ENST00000356311.10chr9_132888907_+1119-807.60-803.80-842.00
ADediting_1453975ENST00000356311.10chr9_132888974_+1186-805.70-803.80-842.00
ADediting_1453976ENST00000356311.10chr9_132888978_+1190-803.10-803.80-842.00
ADediting_1453977ENST00000356311.10chr9_132888989_+1201-803.80-803.80-842.00
ADediting_1453978ENST00000356311.10chr9_132889031_+1243-806.50-803.80-842.00
ADediting_1453979ENST00000356311.10chr9_132889032_+1244-807.00-803.80-842.00
ADediting_1453980ENST00000356311.10chr9_132889044_+1256-803.90-803.80-842.00
ADediting_1453981ENST00000356311.10chr9_132889204_+1416-810.40-803.80-842.00
ADediting_1453982ENST00000356311.10chr9_132889438_+1650-804.10-803.80-842.00
ADediting_1453983ENST00000356311.10chr9_132889468_+1680-804.70-803.80-842.00
ADediting_1453984ENST00000356311.10chr9_132889493_+1705-805.50-803.80-842.00
ADediting_1453985ENST00000356311.10chr9_132889505_+1717-809.80-803.80-842.00
ADediting_1453986ENST00000356311.10chr9_132889506_+1718-808.00-803.80-842.00
ADediting_1453987ENST00000356311.10chr9_132889523_+1735-804.90-803.80-842.00
ADediting_1453988ENST00000356311.10chr9_132889535_+1747-805.90-803.80-842.00
ADediting_1453989ENST00000356311.10chr9_132889545_+1757-806.80-803.80-842.00
ADediting_1453990ENST00000356311.10chr9_132889595_+1807-804.70-803.80-842.00
ADediting_1453991ENST00000356311.10chr9_132889598_+1810-804.30-803.80-842.00
ADediting_1453992ENST00000356311.10chr9_132889658_+1870-803.40-803.80-842.00
ADediting_1453993ENST00000356311.10chr9_132889676_+1888-804.70-803.80-842.00
ADediting_1453994ENST00000356311.10chr9_132889677_+1889-804.30-803.80-842.00
ADediting_1453995ENST00000356311.10chr9_132889689_+1901-804.10-803.80-842.00

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for SPACA9

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_1453963chr9_132881361_+0.6566708246957350.02534504483756140.108498184057049-0.09133509032556923.29481619069513e-160.441338046923492

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.38895316647578e-320.6069378300840572.49188920810986e-350.6274189075838232.21093501480452e-190.481322660073314
AC5.00774755980346e-630.8236332603954248.71805226384275e-350.6763666582604671.09549851278704e-150.478152716296182
PCC1.36742553152155e-220.630823767782921.47920431197908e-210.6186272882272760.001281389529345990.231348849491408
TCX3.3164299909085e-170.6185683221726169.4922931257102e-080.418986384763680.001110798422168950.263723627388759
FP1.40430195936505e-200.6237495396648982.38387045568231e-070.3756241711089912.30853963179538e-110.474124439139819
IFG5.76703419331233e-060.773538905633370.0004515157567781170.6487531042721270.2568038178272830.235647818317368
PG2.67297918766449e-050.3027194537665380.004250265056729610.2087226160094158.03324820860861e-090.40718707386141
STG1.29506328238557e-120.6787245613341010.0001681308176641530.3993049687580140.0036612867252350.31372077784554

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Relation with AD stages for SPACA9

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
TCXADediting_1453989chr9_132889545_+0.001211147426199490.310217253965341

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.

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RelatedDrugs for SPACA9

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SPACA9

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource