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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for DIDO1

check button Gene summary
Gene informationGene symbol

DIDO1

Gene ID

11083

Gene namedeath inducer-obliterator 1
SynonymsBYE1|C20orf158|DATF-1|DATF1|DIDO2|DIDO3|DIO-1|DIO1|dJ885L7.8
Cytomap

20q13.33

Type of geneprotein-coding
Descriptiondeath-inducer obliterator 1death-associated transcription factor 1
Modification date20200313
UniProtAcc

Q9BTC0,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for DIDO1

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_948404(62883001, -), ADediting_948405(62883011, -), ADediting_948406(62883061, -), ADediting_948407(62883062, -), ADediting_948408(62883070, -), ADediting_948409(62883078, -), ADediting_948410(62883080, -), ADediting_948411(62883088, -), ADediting_948412(62883125, -), ADediting_948413(62883196, -), ADediting_948414(62883448, -), ADediting_948415(62883508, -), ADediting_948416(62883511, -), ADediting_948417(62883743, -), ADediting_948418(62883867, -), ADediting_948419(62883875, -), ADediting_948420(62883883, -), ADediting_948421(62883893, -), ADediting_948422(62883923, -), ADediting_948423(62883962, -), ADediting_948424(62908207, -), ADediting_948425(62908231, -), ADediting_948426(62908232, -), ADediting_948427(62908236, -), ADediting_948428(62915241, -), ADediting_948429(62915257, -), ADediting_948430(62915591, -), ADediting_948431(62915627, -), ADediting_948432(62915643, -), ADediting_948433(62915645, -), ADediting_948434(62915758, -), ADediting_948435(62917230, -), ADediting_948436(62917258, -), ADediting_948437(62917273, -), ADediting_948438(62917304, -), ADediting_948439(62917312, -), ADediting_948440(62919428, -), ADediting_948441(62921687, -), ADediting_948442(62922403, -), ADediting_948443(62923304, -), ADediting_948444(62930002, -), ADediting_948445(62930057, -), ADediting_948446(62930077, -), ADediting_948447(62930128, -), ADediting_948448(62930145, -), ADediting_948449(62931001, -), ADediting_948450(62931003, -), ADediting_948451(62931006, -), ADediting_948452(62931008, -), ADediting_948453(62931017, -), ADediting_948454(62931026, -), ADediting_948455(62931030, -), ADediting_948456(62931052, -), ADediting_948457(62931069, -), ADediting_948458(62931079, -), ADediting_948459(62931085, -), ADediting_948460(62931101, -), ADediting_948461(62931105, -), ADediting_948462(62931111, -), ADediting_948463(62931114, -), ADediting_948464(62931116, -), ADediting_948465(62931118, -), ADediting_948466(62931120, -), ADediting_948467(62931123, -), ADediting_948468(62931134, -), ADediting_948469(62931135, -), ADediting_948470(62931136, -), ADediting_948471(62931140, -), ADediting_948472(62931142, -), ADediting_948473(62931144, -), ADediting_948474(62931197, -), ADediting_948475(62931206, -), ADediting_948476(62931245, -), ADediting_948477(62932142, -), ADediting_948478(62932150, -), ADediting_948479(62932154, -), ADediting_948480(62932236, -), ADediting_948481(62932242, -), ADediting_948482(62932248, -), ADediting_948483(62932249, -), ADediting_948484(62932967, -), ADediting_948485(62933047, -), ADediting_948486(62933050, -), ADediting_948487(62933063, -), ADediting_948488(62933064, -), ADediting_948489(62933090, -), ADediting_948490(62933099, -), ADediting_948491(62933100, -), ADediting_948492(62933112, -), ADediting_948493(62933129, -), ADediting_948494(62933167, -), ADediting_948495(62933172, -), ADediting_948496(62933203, -), ADediting_948497(62933206, -), ADediting_948498(62933635, -), ADediting_948499(62933667, -), ADediting_948500(62933687, -), ADediting_948501(62933690, -), ADediting_948502(62933697, -), ADediting_948503(62933704, -), ADediting_948504(62933722, -), ADediting_948505(62933727, -), ADediting_948506(62933741, -), ADediting_948507(62933749, -), ADediting_948508(62933759, -), ADediting_948509(62933776, -), ADediting_948510(62933816, -), ADediting_948511(62933826, -), ADediting_1567859(62915712, -), ADediting_1567860(62917068, -), ADediting_1567861(62917227, -), ADediting_1567862(62930048, -), ADediting_1567863(62930060, -), ADediting_1567864(62930118, -), ADediting_1567865(62930157, -), ADediting_1567866(62930201, -), ADediting_1567867(62931089, -), ADediting_1567868(62931109, -), ADediting_1567869(62931110, -), ADediting_1567870(62931119, -), ADediting_1567871(62931154, -), ADediting_1567872(62931159, -), ADediting_1567873(62931205, -), ADediting_1567874(62931216, -), ADediting_1567875(62931230, -), ADediting_1567876(62932147, -), ADediting_1567877(62932234, -), ADediting_1567878(62932288, -), ADediting_1567879(62932289, -), ADediting_1567880(62932301, -), ADediting_1567881(62933030, -), ADediting_1567882(62933056, -), ADediting_1567883(62933185, -), ADediting_1567884(62933204, -), ADediting_1567885(62933747, -), ADediting_1567886(62933815, -), ADediting_1641323(62908735, -), ADediting_1641324(62908737, -), ADediting_1641325(62908747, -), ADediting_1641326(62908750, -), ADediting_1641327(62915711, -),

Top

RNA editing positional annotations for DIDO1 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_948404chr20_62883001_-intronic
ADediting_948405chr20_62883011_-intronic
ADediting_948406chr20_62883061_-intronic
ADediting_948407chr20_62883062_-intronic
ADediting_948408chr20_62883070_-intronic
ADediting_948409chr20_62883078_-intronic
ADediting_948410chr20_62883080_-intronic
ADediting_948411chr20_62883088_-intronic
ADediting_948412chr20_62883125_-intronic
ADediting_948413chr20_62883196_-intronic
ADediting_948414chr20_62883448_-intronic
ADediting_948415chr20_62883508_-intronic
ADediting_948416chr20_62883511_-intronic
ADediting_948417chr20_62883743_-intronic
ADediting_948418chr20_62883867_-intronic
ADediting_948419chr20_62883875_-intronic
ADediting_948420chr20_62883883_-intronic
ADediting_948421chr20_62883893_-intronic
ADediting_948422chr20_62883923_-intronic
ADediting_948423chr20_62883962_-intronic
ADediting_948424chr20_62908207_-intronic
ADediting_948425chr20_62908231_-intronic
ADediting_948426chr20_62908232_-intronic
ADediting_948427chr20_62908236_-intronic
ADediting_948428chr20_62915241_-intronic
ADediting_948429chr20_62915257_-intronic
ADediting_948430chr20_62915591_-intronic
ADediting_948431chr20_62915627_-intronic
ADediting_948432chr20_62915643_-intronic
ADediting_948433chr20_62915645_-intronic
ADediting_948434chr20_62915758_-intronic
ADediting_948435chr20_62917230_-intronic
ADediting_948436chr20_62917258_-intronic
ADediting_948437chr20_62917273_-intronic
ADediting_948438chr20_62917304_-intronic
ADediting_948439chr20_62917312_-intronic
ADediting_948440chr20_62919428_-intronic
ADediting_948441chr20_62921687_-intronic
ADediting_948442chr20_62922403_-intronic
ADediting_948443chr20_62923304_-intronic
ADediting_948444chr20_62930002_-intronic
ADediting_948445chr20_62930057_-intronic
ADediting_948446chr20_62930077_-intronic
ADediting_948447chr20_62930128_-intronic
ADediting_948448chr20_62930145_-intronic
ADediting_948449chr20_62931001_-intronic
ADediting_948450chr20_62931003_-intronic
ADediting_948451chr20_62931006_-intronic
ADediting_948452chr20_62931008_-intronic
ADediting_948453chr20_62931017_-intronic
ADediting_948454chr20_62931026_-intronic
ADediting_948455chr20_62931030_-intronic
ADediting_948456chr20_62931052_-intronic
ADediting_948457chr20_62931069_-intronic
ADediting_948458chr20_62931079_-intronic
ADediting_948459chr20_62931085_-intronic
ADediting_948460chr20_62931101_-intronic
ADediting_948461chr20_62931105_-intronic
ADediting_948462chr20_62931111_-intronic
ADediting_948463chr20_62931114_-intronic
ADediting_948464chr20_62931116_-intronic
ADediting_948465chr20_62931118_-intronic
ADediting_948466chr20_62931120_-intronic
ADediting_948467chr20_62931123_-intronic
ADediting_948468chr20_62931134_-intronic
ADediting_948469chr20_62931135_-intronic
ADediting_948470chr20_62931136_-intronic
ADediting_948471chr20_62931140_-intronic
ADediting_948472chr20_62931142_-intronic
ADediting_948473chr20_62931144_-intronic
ADediting_948474chr20_62931197_-intronic
ADediting_948475chr20_62931206_-intronic
ADediting_948476chr20_62931245_-intronic
ADediting_948477chr20_62932142_-intronic
ADediting_948478chr20_62932150_-intronic
ADediting_948479chr20_62932154_-intronic
ADediting_948480chr20_62932236_-intronic
ADediting_948481chr20_62932242_-intronic
ADediting_948482chr20_62932248_-intronic
ADediting_948483chr20_62932249_-intronic
ADediting_948484chr20_62932967_-intronic
ADediting_948485chr20_62933047_-intronic
ADediting_948486chr20_62933050_-intronic
ADediting_948487chr20_62933063_-intronic
ADediting_948488chr20_62933064_-intronic
ADediting_948489chr20_62933090_-intronic
ADediting_948490chr20_62933099_-intronic
ADediting_948491chr20_62933100_-intronic
ADediting_948492chr20_62933112_-intronic
ADediting_948493chr20_62933129_-intronic
ADediting_948494chr20_62933167_-intronic
ADediting_948495chr20_62933172_-intronic
ADediting_948496chr20_62933203_-intronic
ADediting_948497chr20_62933206_-intronic
ADediting_948498chr20_62933635_-intronic
ADediting_948499chr20_62933667_-intronic
ADediting_948500chr20_62933687_-intronic
ADediting_948501chr20_62933690_-intronic
ADediting_948502chr20_62933697_-intronic
ADediting_948503chr20_62933704_-intronic
ADediting_948504chr20_62933722_-intronic
ADediting_948505chr20_62933727_-intronic
ADediting_948506chr20_62933741_-intronic
ADediting_948507chr20_62933749_-intronic
ADediting_948508chr20_62933759_-intronic
ADediting_948509chr20_62933776_-intronic
ADediting_948510chr20_62933816_-intronic
ADediting_948511chr20_62933826_-intronic
ADediting_1567859chr20_62915712_-intronic
ADediting_1567860chr20_62917068_-intronic
ADediting_1567861chr20_62917227_-intronic
ADediting_1567862chr20_62930048_-intronic
ADediting_1567863chr20_62930060_-intronic
ADediting_1567864chr20_62930118_-intronic
ADediting_1567865chr20_62930157_-intronic
ADediting_1567866chr20_62930201_-intronic
ADediting_1567867chr20_62931089_-intronic
ADediting_1567868chr20_62931109_-intronic
ADediting_1567869chr20_62931110_-intronic
ADediting_1567870chr20_62931119_-intronic
ADediting_1567871chr20_62931154_-intronic
ADediting_1567872chr20_62931159_-intronic
ADediting_1567873chr20_62931205_-intronic
ADediting_1567874chr20_62931216_-intronic
ADediting_1567875chr20_62931230_-intronic
ADediting_1567876chr20_62932147_-intronic
ADediting_1567877chr20_62932234_-intronic
ADediting_1567878chr20_62932288_-intronic
ADediting_1567879chr20_62932289_-intronic
ADediting_1567880chr20_62932301_-intronic
ADediting_1567881chr20_62933030_-intronic
ADediting_1567882chr20_62933056_-intronic
ADediting_1567883chr20_62933185_-intronic
ADediting_1567884chr20_62933204_-intronic
ADediting_1567885chr20_62933747_-intronic
ADediting_1567886chr20_62933815_-intronic
ADediting_1641323chr20_62908735_-intronic
ADediting_1641324chr20_62908737_-intronic
ADediting_1641325chr20_62908747_-intronic
ADediting_1641326chr20_62908750_-intronic
ADediting_1641327chr20_62915711_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_948404chr20_62883001_-SINEAluName=AluSx
ADediting_948405chr20_62883011_-SINEAluName=AluSx
ADediting_948406chr20_62883061_-SINEAluName=AluSx
ADediting_948407chr20_62883062_-SINEAluName=AluSx
ADediting_948408chr20_62883070_-SINEAluName=AluSx
ADediting_948409chr20_62883078_-SINEAluName=AluSx
ADediting_948410chr20_62883080_-SINEAluName=AluSx
ADediting_948411chr20_62883088_-SINEAluName=AluSx
ADediting_948412chr20_62883125_-SINEAluName=AluSx
ADediting_948413chr20_62883196_-SINEAluName=AluSx
ADediting_948414chr20_62883448_-SINEAluName=AluSx3
ADediting_948415chr20_62883508_-SINEAluName=AluSx3
ADediting_948416chr20_62883511_-SINEAluName=AluSx3
ADediting_948417chr20_62883743_-SINEAluName=AluSc
ADediting_948418chr20_62883867_-SINEAluName=AluSx3
ADediting_948419chr20_62883875_-SINEAluName=AluSx3
ADediting_948420chr20_62883883_-SINEAluName=AluSx3
ADediting_948421chr20_62883893_-SINEAluName=AluSx3
ADediting_948422chr20_62883923_-SINEAluName=AluSx3
ADediting_948423chr20_62883962_-SINEAluName=AluSx3
ADediting_948424chr20_62908207_-SINEAluName=AluJr
ADediting_948425chr20_62908231_-SINEAluName=AluJr
ADediting_948426chr20_62908232_-SINEAluName=AluJr
ADediting_948427chr20_62908236_-SINEAluName=AluJr
ADediting_948428chr20_62915241_-SINEAluName=AluJo
ADediting_948429chr20_62915257_-SINEAluName=AluJo
ADediting_948430chr20_62915591_-SINEAluName=AluJr
ADediting_948431chr20_62915627_-SINEAluName=AluJr
ADediting_948432chr20_62915643_-SINEAluName=AluJr
ADediting_948433chr20_62915645_-SINEAluName=AluJr
ADediting_948434chr20_62915758_-SINEAluName=AluJr
ADediting_948435chr20_62917230_-SINEAluName=AluJb
ADediting_948436chr20_62917258_-SINEAluName=AluJb
ADediting_948437chr20_62917273_-SINEAluName=AluJb
ADediting_948438chr20_62917304_-SINEAluName=AluJb
ADediting_948439chr20_62917312_-SINEAluName=AluJb
ADediting_948440chr20_62919428_-SINEAluName=AluSq
ADediting_948441chr20_62921687_-SINEAluName=AluJb
ADediting_948443chr20_62923304_-SINEAluName=AluSz
ADediting_948444chr20_62930002_-SINEAluName=AluSx1
ADediting_948445chr20_62930057_-SINEAluName=AluSx1
ADediting_948446chr20_62930077_-SINEAluName=AluSx1
ADediting_948447chr20_62930128_-SINEAluName=AluSx1
ADediting_948448chr20_62930145_-SINEAluName=AluSx1
ADediting_948449chr20_62931001_-SINEAluName=AluJb
ADediting_948450chr20_62931003_-SINEAluName=AluJb
ADediting_948451chr20_62931006_-SINEAluName=AluJb
ADediting_948452chr20_62931008_-SINEAluName=AluJb
ADediting_948453chr20_62931017_-SINEAluName=AluJb
ADediting_948454chr20_62931026_-SINEAluName=AluJb
ADediting_948455chr20_62931030_-SINEAluName=AluJb
ADediting_948456chr20_62931052_-SINEAluName=AluJb
ADediting_948457chr20_62931069_-SINEAluName=AluJb
ADediting_948458chr20_62931079_-SINEAluName=AluJb
ADediting_948459chr20_62931085_-SINEAluName=AluJb
ADediting_948460chr20_62931101_-SINEAluName=AluJb
ADediting_948461chr20_62931105_-SINEAluName=AluJb
ADediting_948462chr20_62931111_-SINEAluName=AluJb
ADediting_948463chr20_62931114_-SINEAluName=AluJb
ADediting_948464chr20_62931116_-SINEAluName=AluJb
ADediting_948465chr20_62931118_-SINEAluName=AluJb
ADediting_948466chr20_62931120_-SINEAluName=AluJb
ADediting_948467chr20_62931123_-SINEAluName=AluJb
ADediting_948468chr20_62931134_-SINEAluName=AluJb
ADediting_948469chr20_62931135_-SINEAluName=AluJb
ADediting_948470chr20_62931136_-SINEAluName=AluJb
ADediting_948471chr20_62931140_-SINEAluName=AluJb
ADediting_948472chr20_62931142_-SINEAluName=AluJb
ADediting_948473chr20_62931144_-SINEAluName=AluJb
ADediting_948474chr20_62931197_-SINEAluName=AluJb
ADediting_948475chr20_62931206_-SINEAluName=AluJb
ADediting_948477chr20_62932142_-SINEAluName=FLAM_C
ADediting_948478chr20_62932150_-SINEAluName=FLAM_C
ADediting_948479chr20_62932154_-SINEAluName=FLAM_C
ADediting_948480chr20_62932236_-SINEAluName=AluJb
ADediting_948481chr20_62932242_-SINEAluName=AluJb
ADediting_948482chr20_62932248_-SINEAluName=AluJb
ADediting_948483chr20_62932249_-SINEAluName=AluJb
ADediting_948484chr20_62932967_-SINEAluName=AluSp
ADediting_948485chr20_62933047_-SINEAluName=AluSp
ADediting_948486chr20_62933050_-SINEAluName=AluSp
ADediting_948487chr20_62933063_-SINEAluName=AluSp
ADediting_948488chr20_62933064_-SINEAluName=AluSp
ADediting_948489chr20_62933090_-SINEAluName=AluSp
ADediting_948490chr20_62933099_-SINEAluName=AluSp
ADediting_948491chr20_62933100_-SINEAluName=AluSp
ADediting_948492chr20_62933112_-SINEAluName=AluSp
ADediting_948493chr20_62933129_-SINEAluName=AluSp
ADediting_948494chr20_62933167_-SINEAluName=AluSp
ADediting_948495chr20_62933172_-SINEAluName=AluSp
ADediting_948496chr20_62933203_-SINEAluName=AluSp
ADediting_948497chr20_62933206_-SINEAluName=AluSp
ADediting_948498chr20_62933635_-SINEAluName=AluJb
ADediting_948499chr20_62933667_-SINEAluName=AluJb
ADediting_948500chr20_62933687_-SINEAluName=AluJb
ADediting_948501chr20_62933690_-SINEAluName=AluJb
ADediting_948502chr20_62933697_-SINEAluName=AluJb
ADediting_948503chr20_62933704_-SINEAluName=AluJb
ADediting_948504chr20_62933722_-SINEAluName=AluJb
ADediting_948505chr20_62933727_-SINEAluName=AluJb
ADediting_948506chr20_62933741_-SINEAluName=AluJb
ADediting_948507chr20_62933749_-SINEAluName=AluJb
ADediting_948508chr20_62933759_-SINEAluName=AluJb
ADediting_948509chr20_62933776_-SINEAluName=AluJb
ADediting_948510chr20_62933816_-SINEAluName=AluJb
ADediting_948511chr20_62933826_-SINEAluName=AluJb
ADediting_1567859chr20_62915712_-SINEAluName=AluJr
ADediting_1567860chr20_62917068_-SINEAluName=AluJb
ADediting_1567861chr20_62917227_-SINEAluName=AluJb
ADediting_1567862chr20_62930048_-SINEAluName=AluSx1
ADediting_1567863chr20_62930060_-SINEAluName=AluSx1
ADediting_1567864chr20_62930118_-SINEAluName=AluSx1
ADediting_1567865chr20_62930157_-SINEAluName=AluSx1
ADediting_1567866chr20_62930201_-SINEAluName=AluSx1
ADediting_1567867chr20_62931089_-SINEAluName=AluJb
ADediting_1567868chr20_62931109_-SINEAluName=AluJb
ADediting_1567869chr20_62931110_-SINEAluName=AluJb
ADediting_1567870chr20_62931119_-SINEAluName=AluJb
ADediting_1567871chr20_62931154_-SINEAluName=AluJb
ADediting_1567872chr20_62931159_-SINEAluName=AluJb
ADediting_1567873chr20_62931205_-SINEAluName=AluJb
ADediting_1567874chr20_62931216_-SINEAluName=AluJb
ADediting_1567875chr20_62931230_-SINEAluName=AluJb
ADediting_1567876chr20_62932147_-SINEAluName=FLAM_C
ADediting_1567877chr20_62932234_-SINEAluName=AluJb
ADediting_1567878chr20_62932288_-SINEAluName=AluJb
ADediting_1567879chr20_62932289_-SINEAluName=AluJb
ADediting_1567880chr20_62932301_-SINEAluName=AluJb
ADediting_1567881chr20_62933030_-SINEAluName=AluSp
ADediting_1567882chr20_62933056_-SINEAluName=AluSp
ADediting_1567883chr20_62933185_-SINEAluName=AluSp
ADediting_1567884chr20_62933204_-SINEAluName=AluSp
ADediting_1567885chr20_62933747_-SINEAluName=AluJb
ADediting_1567886chr20_62933815_-SINEAluName=AluJb
ADediting_1641323chr20_62908735_-SINEAluName=FRAM
ADediting_1641324chr20_62908737_-SINEAluName=FRAM
ADediting_1641325chr20_62908747_-SINEAluName=FRAM
ADediting_1641326chr20_62908750_-SINEAluName=FRAM
ADediting_1641327chr20_62915711_-SINEAluName=AluJr

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RNA A-to-I editing events in the alternative splicing sites for DIDO1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for DIDO1

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for DIDO1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for DIDO1


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1097295chr3_85385762_+ENSG00000101191.16ENST00000266070.8DIDO1-201hsa-miR-5688chr2062878368628783747mer-m86287836762878392146-11.48
ADediting_1097295chr3_85385762_+ENSG00000101191.16ENST00000395343.5DIDO1-207hsa-miR-5688chr2062878368628783747mer-m86287836762878392146-11.48
ADediting_1337757chr7_5495852_-ENSG00000101191.16ENST00000395340.5DIDO1-206hsa-miR-589-3pchr2062890321628903277mer-m86289032062890343146-21.59
ADediting_1337758chr7_5495892_-ENSG00000101191.16ENST00000395340.5DIDO1-206hsa-miR-589-5pchr2062889323628893297mer-m86288932262889341152-22.61
ADediting_1535951chr14_100874558_+ENSG00000101191.16ENST00000266070.8DIDO1-201hsa-miR-337-3pchr2062877743628777508mer-1a6287774362877764153-12.53
ADediting_1535951chr14_100874558_+ENSG00000101191.16ENST00000395340.5DIDO1-206hsa-miR-337-3pchr2062887676628876827mer-m86288767562887695153-15.51
ADediting_1535951chr14_100874558_+ENSG00000101191.16ENST00000395343.5DIDO1-207hsa-miR-337-3pchr2062877743628777508mer-1a6287774362877764153-12.53
ADediting_1535953chr14_101045971_+ENSG00000101191.16ENST00000395340.5DIDO1-206hsa-miR-381-3pchr2062887969628879768mer-1a6288796962887989166-24.83
ADediting_1631458chr19_40282624_-ENSG00000101191.16ENST00000395340.5DIDO1-206hsa-miR-641chr2062888862628888687mer-m86288886162888884163-18.65
ADediting_496066chr15_66496985_-ENSG00000101191.16ENST00000354665.8DIDO1-202hsa-miR-4512chr2062905259629052668mer-1a6290525962905278142-14.49
ADediting_496066chr15_66496985_-ENSG00000101191.16ENST00000370366.1DIDO1-203hsa-miR-4512chr2062905259629052668mer-1a6290525962905278142-14.49
ADediting_496066chr15_66496985_-ENSG00000101191.16ENST00000370368.5DIDO1-204hsa-miR-4512chr2062905259629052668mer-1a6290525962905278142-14.49
ADediting_496066chr15_66496985_-ENSG00000101191.16ENST00000370371.8DIDO1-205hsa-miR-4512chr2062905259629052668mer-1a6290525962905278142-14.49
ADediting_843620chr2_207754818_+ENSG00000101191.16ENST00000266070.8DIDO1-201hsa-miR-4775chr2062877877628778848mer-1a6287787762877899157-7.61
ADediting_843620chr2_207754818_+ENSG00000101191.16ENST00000395343.5DIDO1-207hsa-miR-4775chr2062877877628778848mer-1a6287787762877899157-7.61

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_107020chr1_37500952_-ENSG00000101191.16ENST00000395340.5DIDO1-206hsa-miR-5581-3pchr2062887294628873018mer-1a6288729462887315140-13.48
ADediting_1097295chr3_85385762_+ENSG00000101191.16ENST00000266070.8DIDO1-201hsa-miR-5688chr2062877928628779347mer-m86287792762877948145-10.45
ADediting_1097295chr3_85385762_+ENSG00000101191.16ENST00000395343.5DIDO1-207hsa-miR-5688chr2062877928628779347mer-m86287792762877948145-10.45
ADediting_1337757chr7_5495852_-ENSG00000101191.16ENST00000354665.8DIDO1-202hsa-miR-589-3pchr2062905502629055098mer-1a6290550262905524149-18.75
ADediting_1337757chr7_5495852_-ENSG00000101191.16ENST00000370366.1DIDO1-203hsa-miR-589-3pchr2062905502629055098mer-1a6290550262905524149-18.75
ADediting_1337757chr7_5495852_-ENSG00000101191.16ENST00000370368.5DIDO1-204hsa-miR-589-3pchr2062905502629055098mer-1a6290550262905524149-18.75
ADediting_1337757chr7_5495852_-ENSG00000101191.16ENST00000370371.8DIDO1-205hsa-miR-589-3pchr2062905502629055098mer-1a6290550262905524149-18.75
ADediting_1535953chr14_101045971_+ENSG00000101191.16ENST00000266070.8DIDO1-201hsa-miR-381-3pchr2062878769628787757mer-m86287876862878791150-14.21
ADediting_1535953chr14_101045971_+ENSG00000101191.16ENST00000395343.5DIDO1-207hsa-miR-381-3pchr2062878769628787757mer-m86287876862878791150-14.21
ADediting_1535954chr14_101045974_+ENSG00000101191.16ENST00000266070.8DIDO1-201hsa-miR-381-3pchr2062878769628787757mer-m86287876862878791150-14.21
ADediting_1535954chr14_101045974_+ENSG00000101191.16ENST00000395343.5DIDO1-207hsa-miR-381-3pchr2062878769628787757mer-m86287876862878791150-14.21
ADediting_291761chr11_93733708_-ENSG00000101191.16ENST00000395340.5DIDO1-206hsa-miR-1304-3pchr2062888053628880608mer-1a6288805362888074141-19.36
ADediting_527135chr16_24203190_+ENSG00000101191.16ENST00000354665.8DIDO1-202hsa-miR-1273h-3pchr2062905517629055237mer-m86290551662905537140-11.82
ADediting_527135chr16_24203190_+ENSG00000101191.16ENST00000370366.1DIDO1-203hsa-miR-1273h-3pchr2062905517629055237mer-m86290551662905537140-11.82
ADediting_527135chr16_24203190_+ENSG00000101191.16ENST00000370368.5DIDO1-204hsa-miR-1273h-3pchr2062905517629055237mer-m86290551662905537140-11.82
ADediting_527135chr16_24203190_+ENSG00000101191.16ENST00000370371.8DIDO1-205hsa-miR-1273h-3pchr2062905517629055237mer-m86290551662905537140-11.82
ADediting_527135chr16_24203190_+ENSG00000101191.16ENST00000395340.5DIDO1-206hsa-miR-1273h-3pchr2062888365628883717mer-m86288836462888386147-18.79
ADediting_843620chr2_207754818_+ENSG00000101191.16ENST00000266070.8DIDO1-201hsa-miR-4775chr2062878138628781458mer-1a6287813862878159150-6.05
ADediting_843620chr2_207754818_+ENSG00000101191.16ENST00000266070.8DIDO1-201hsa-miR-4775chr2062879014628790218mer-1a6287901462879035140-4.93
ADediting_843620chr2_207754818_+ENSG00000101191.16ENST00000395343.5DIDO1-207hsa-miR-4775chr2062878138628781458mer-1a6287813862878159150-6.05
ADediting_843620chr2_207754818_+ENSG00000101191.16ENST00000395343.5DIDO1-207hsa-miR-4775chr2062879014628790218mer-1a6287901462879035140-4.93

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for DIDO1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for DIDO1

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_948404chr20_62883001_-0.79320248606404-0.01494892159376970.0113468521080517-0.1436322407202011.23925766507781e-210.506815935147729
DLPFCADediting_948406chr20_62883061_-0.976636577981261-0.001670072475641210.02459557848503-0.1276535407712072.98947320966469e-180.467664448969813
DLPFCADediting_948408chr20_62883070_-0.8416421152313-0.01139316340347440.0191446926674066-0.1330021482051721.63423341659142e-170.458414705482383
DLPFCADediting_948409chr20_62883078_-0.839281217373847-0.01156533874990940.0215128229990609-0.1305347386942991.41809613833182e-170.459197991967978
DLPFCADediting_948412chr20_62883125_-0.242561321963479-0.06656778819168310.00399465724716878-0.1630557070403122.18691686892584e-130.400730642560103
DLPFCADediting_948414chr20_62883448_-0.486461979788319-0.0396718382173780.0505363953495823-0.1111636446773486.53907422159875e-100.341593057121233
DLPFCADediting_948416chr20_62883511_-0.873088685070375-0.009109030893350760.172675591364734-0.07764720407708229.62575403830544e-090.318607140089495
DLPFCADediting_948419chr20_62883875_-0.049189168600803-0.1118163017171980.00129444626847972-0.1819328074378623.55211865104439e-080.306710302521945
DLPFCADediting_948420chr20_62883883_-0.171233119067096-0.07790807593420180.00989546526878266-0.1463054227049372.18081193563066e-100.350461115660327
DLPFCADediting_948421chr20_62883893_-0.798909199640842-0.01452726517856620.0180479052735124-0.1342360745182491.76161729093697e-200.494029547268907
DLPFCADediting_948422chr20_62883923_-0.431016299544282-0.04488314054040630.0113669226662446-0.1435974460649085.33168932412203e-120.378548974804394
DLPFCADediting_948423chr20_62883962_-0.0243601164219205-0.1278622587521620.000342131790433124-0.2021072040146374.51107610630842e-090.325281102687416
DLPFCADediting_948448chr20_62930145_-0.04650365062885540.113163147138250.9756682942943830.001739308612304628.13779377664344e-100.339792889669241
DLPFCADediting_948452chr20_62931008_-0.005888571671569160.1560830793035060.6244904499555690.02790884421941129.48070223881267e-130.390749778629609
DLPFCADediting_948454chr20_62931026_-0.001686727877920130.1776637636319870.8809722695379030.008538818761336936.66705526344298e-160.437188233725232
TCXADediting_948479chr20_62932154_-0.7117765402510790.0304146480376320.0343198170312877-0.1729372375042364.41524414033191e-070.398467089073926
CERADediting_948482chr20_62932248_-2.19901915337997e-050.3390122058730250.003137793604802850.2396651016612110.9747246539994140.00260874545581621
DLPFCADediting_948495chr20_62933172_-0.01945299587461130.1326663842893650.809715302276519-0.01373096693871992.93421462499102e-220.513537221715689
CERADediting_948500chr20_62933687_-9.06299345759499e-050.314109170607320.00118794990268650.2622342745302120.1741209557679550.111555009268571
TCXADediting_948503chr20_62933704_-0.8751534742766090.01293614316466780.016355268036397-0.1957687629119391.43769098658149e-050.346084877248424
TCXADediting_948511chr20_62933826_-0.3848660877013130.07145774398106010.0258685303576177-0.1819309838540521.21950465114915e-060.384107254917898

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC2.04386196061817e-570.7507873601617424.0736336731618e-630.7741128508386541.37622567258082e-080.315401599735464
AC6.73758013993055e-550.7912564806527219.40912427975337e-350.676120963397639.29331709317165e-310.644640525398431
PCC2.3022617391481e-260.6711766023883636.06132307085349e-230.6348703660129954.38205988215478e-120.473888721528688
CER5.92115287214445e-340.7950874070467585.05423621381366e-490.8772363823191358.42838422608599e-060.354737074230592
TCX5.39150619117312e-210.6713403141755930.0002290626943312320.2965315674276948.17399200642321e-170.6124831066935
FP3.19413160092165e-380.7835705511353992.15191781522277e-140.5319697131804067.00111152845352e-150.540334819627756
IFG3.33607582123691e-070.8275787497107776.13803478530648e-060.7721619840879730.0006506719232721410.634924053765641
PG1.12106550637954e-280.6997121332106425.89247474607054e-220.6299006535398481.07768932348549e-060.348656657086072
STG4.65614272119033e-170.7607082000615213.92235711133985e-070.5202919597842011.18403837971718e-060.501404311916431

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Relation with AD stages for DIDO1

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
TCXADediting_948479chr20_62932154_-0.0009624084589324370.316133196375057

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER3.8035291071861e-100.557115669045273
TCX7.19034024262173e-090.525697155667912

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RelatedDrugs for DIDO1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for DIDO1

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource