ADeditome: functional annotation of RNA A-to-I editing in AD

Gene summary for SERINC3

Gene summary

Gene information	Gene symbol	SERINC3
	Gene ID	10955
	Gene name	serine incorporator 3
	Synonyms	AIGP1\|DIFF33\|SBBI99\|TDE\|TDE1\|TMS-1
	Cytomap	20q13.12
	Type of gene	protein-coding
	Description	serine incorporator 3tumor differentially expressed protein 1
	Modification date	20200313
	UniProtAcc	Q13530,
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
SERINC3	GO:0009597	detection of virus	26416733\|26416734
SERINC3	GO:0045087	innate immune response	26416733\|26416734
SERINC3	GO:0051607	defense response to virus	26416733\|26416734

Top

RNA A-to-I events for SERINC3

RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA editing frequencies across three data sets.

The number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA A-to-I editing events in AD.

ADediting_937043(44496559, -), ADediting_937044(44498385, -), ADediting_937045(44498454, -), ADediting_937046(44498464, -), ADediting_937047(44498537, -), ADediting_937048(44502390, -), ADediting_937049(44502413, -), ADediting_937050(44502439, -), ADediting_937051(44502459, -), ADediting_937052(44502461, -), ADediting_937053(44502466, -), ADediting_937054(44502471, -), ADediting_937055(44502514, -), ADediting_937056(44502515, -), ADediting_937057(44502523, -), ADediting_937058(44502545, -), ADediting_937059(44502549, -), ADediting_937060(44502575, -), ADediting_937061(44502578, -), ADediting_937062(44502666, -), ADediting_937063(44502688, -), ADediting_937064(44502696, -), ADediting_937065(44502701, -), ADediting_937066(44502735, -), ADediting_937067(44502739, -), ADediting_937068(44502745, -), ADediting_937069(44502766, -), ADediting_937070(44502770, -), ADediting_937071(44502796, -), ADediting_937072(44502810, -), ADediting_937073(44502847, -), ADediting_937074(44502856, -), ADediting_937075(44502863, -), ADediting_937076(44502892, -), ADediting_937077(44503404, -), ADediting_937078(44503405, -), ADediting_937079(44503476, -), ADediting_937080(44503526, -), ADediting_937081(44503531, -), ADediting_937082(44503536, -), ADediting_937083(44503539, -), ADediting_937084(44503585, -), ADediting_937085(44503604, -), ADediting_937086(44503610, -), ADediting_937087(44505359, -), ADediting_937088(44505386, -), ADediting_937089(44505398, -), ADediting_937090(44505446, -), ADediting_937091(44505460, -), ADediting_937092(44505489, -), ADediting_937093(44505497, -), ADediting_937094(44505594, -), ADediting_937095(44505678, -), ADediting_937096(44505739, -), ADediting_937097(44505765, -), ADediting_937098(44505773, -), ADediting_937099(44505776, -), ADediting_937100(44505782, -), ADediting_937101(44505788, -), ADediting_937102(44505807, -), ADediting_937103(44505818, -), ADediting_937104(44505827, -), ADediting_937105(44505850, -), ADediting_937106(44505851, -), ADediting_937107(44506056, -), ADediting_937108(44506109, -), ADediting_937109(44506138, -), ADediting_937110(44506144, -), ADediting_937111(44506221, -), ADediting_937112(44506350, -), ADediting_937113(44506414, -), ADediting_937114(44506420, -), ADediting_937115(44506438, -), ADediting_937116(44506464, -), ADediting_937117(44506502, -), ADediting_937118(44506538, -), ADediting_937119(44507614, -), ADediting_937120(44507745, -), ADediting_937121(44508301, -), ADediting_937122(44509559, -), ADediting_937123(44509718, -), ADediting_937124(44509780, -), ADediting_937125(44510579, -), ADediting_937126(44510588, -), ADediting_937127(44510632, -), ADediting_937128(44510646, -), ADediting_937129(44510650, -), ADediting_937130(44510655, -), ADediting_937131(44510668, -), ADediting_937132(44510688, -), ADediting_937133(44510700, -), ADediting_937134(44510703, -), ADediting_937135(44510712, -), ADediting_937136(44510725, -), ADediting_937137(44510728, -), ADediting_937138(44510748, -), ADediting_937139(44510749, -), ADediting_937140(44510759, -), ADediting_937141(44510767, -), ADediting_937142(44510981, -), ADediting_937143(44510982, -), ADediting_937144(44510999, -), ADediting_937145(44511010, -), ADediting_937146(44511021, -), ADediting_937147(44511038, -), ADediting_937148(44511042, -), ADediting_937149(44511074, -), ADediting_937150(44511078, -), ADediting_937151(44511081, -), ADediting_937152(44511082, -), ADediting_937153(44511084, -), ADediting_937154(44511087, -), ADediting_937155(44511096, -), ADediting_937156(44511108, -), ADediting_937157(44511126, -), ADediting_937158(44511141, -), ADediting_937159(44511164, -), ADediting_937160(44511165, -), ADediting_937161(44511186, -), ADediting_937162(44511187, -), ADediting_937163(44511203, -), ADediting_937164(44513361, -), ADediting_937165(44513403, -), ADediting_937166(44513423, -), ADediting_937167(44514570, -), ADediting_937168(44514613, -), ADediting_937169(44514709, -), ADediting_937170(44515137, -), ADediting_937171(44515174, -), ADediting_937172(44515191, -), ADediting_937173(44515226, -), ADediting_937174(44515230, -), ADediting_937175(44515254, -), ADediting_937176(44515267, -), ADediting_937177(44515271, -), ADediting_937178(44515285, -), ADediting_937179(44515291, -), ADediting_937180(44515297, -), ADediting_937181(44515302, -), ADediting_937182(44515340, -), ADediting_937183(44515346, -), ADediting_937184(44515743, -), ADediting_937185(44515759, -), ADediting_937186(44515765, -), ADediting_937187(44515766, -), ADediting_937188(44515767, -), ADediting_937189(44515789, -), ADediting_937190(44515815, -), ADediting_937191(44515849, -), ADediting_937192(44515851, -), ADediting_937193(44515852, -), ADediting_937194(44515859, -), ADediting_937195(44515874, -), ADediting_937196(44515941, -), ADediting_937197(44515944, -), ADediting_937198(44516078, -), ADediting_937199(44516119, -), ADediting_937200(44516122, -), ADediting_937201(44516139, -), ADediting_937202(44516154, -), ADediting_937203(44516180, -), ADediting_937204(44516202, -), ADediting_937205(44516239, -), ADediting_937206(44516245, -), ADediting_937207(44516255, -), ADediting_937208(44516288, -), ADediting_937209(44516428, -), ADediting_937210(44516485, -), ADediting_937211(44516490, -), ADediting_937212(44516505, -), ADediting_937213(44516511, -), ADediting_937214(44516527, -), ADediting_937215(44516528, -), ADediting_937216(44516563, -), ADediting_937217(44516566, -), ADediting_937218(44516608, -), ADediting_937219(44516615, -), ADediting_937220(44516619, -), ADediting_937221(44516634, -), ADediting_937222(44516664, -), ADediting_937223(44516787, -), ADediting_937224(44516792, -), ADediting_1566920(44502312, -), ADediting_1566921(44502453, -), ADediting_1566922(44502465, -), ADediting_1566923(44502521, -), ADediting_1566924(44502526, -), ADediting_1566925(44502695, -), ADediting_1566926(44502713, -), ADediting_1566927(44502714, -), ADediting_1566928(44502751, -), ADediting_1566929(44502774, -), ADediting_1566930(44502793, -), ADediting_1566931(44502800, -), ADediting_1566932(44502853, -), ADediting_1566933(44503403, -), ADediting_1566934(44503413, -), ADediting_1566935(44503562, -), ADediting_1566936(44507761, -), ADediting_1566937(44508401, -), ADediting_1566938(44509591, -), ADediting_1566939(44509602, -), ADediting_1566940(44509644, -), ADediting_1566941(44509645, -), ADediting_1566942(44509653, -), ADediting_1566943(44509657, -), ADediting_1566944(44509669, -), ADediting_1566945(44509689, -), ADediting_1566946(44509712, -), ADediting_1566947(44510620, -), ADediting_1566948(44510663, -), ADediting_1566949(44510664, -), ADediting_1566950(44510674, -), ADediting_1566951(44510677, -), ADediting_1566952(44511035, -), ADediting_1566953(44511060, -), ADediting_1566954(44511083, -), ADediting_1566955(44511089, -), ADediting_1566956(44511178, -), ADediting_1566957(44513358, -), ADediting_1640898(44498324, -), ADediting_1640899(44505778, -), ADediting_1640900(44506075, -), ADediting_1640901(44508393, -), ADediting_1640902(44509729, -), ADediting_1640903(44510990, -), ADediting_1640904(44511091, -), ADediting_1640905(44511118, -), ADediting_1640906(44511170, -),

Top

RNA editing positional annotations for SERINC3 using Annovar

Protein coding RNA editing(s).

ADeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

ADeditome ID	Position	Variant type
ADediting_937043	chr20_44496559_-	intronic
ADediting_937044	chr20_44498385_-	UTR3
ADediting_937045	chr20_44498454_-	UTR3
ADediting_937046	chr20_44498464_-	UTR3
ADediting_937047	chr20_44498537_-	UTR3
ADediting_937048	chr20_44502390_-	intronic
ADediting_937049	chr20_44502413_-	intronic
ADediting_937050	chr20_44502439_-	intronic
ADediting_937051	chr20_44502459_-	intronic
ADediting_937052	chr20_44502461_-	intronic
ADediting_937053	chr20_44502466_-	intronic
ADediting_937054	chr20_44502471_-	intronic
ADediting_937055	chr20_44502514_-	intronic
ADediting_937056	chr20_44502515_-	intronic
ADediting_937057	chr20_44502523_-	intronic
ADediting_937058	chr20_44502545_-	intronic
ADediting_937059	chr20_44502549_-	intronic
ADediting_937060	chr20_44502575_-	intronic
ADediting_937061	chr20_44502578_-	intronic
ADediting_937062	chr20_44502666_-	intronic
ADediting_937063	chr20_44502688_-	intronic
ADediting_937064	chr20_44502696_-	intronic
ADediting_937065	chr20_44502701_-	intronic
ADediting_937066	chr20_44502735_-	intronic
ADediting_937067	chr20_44502739_-	intronic
ADediting_937068	chr20_44502745_-	intronic
ADediting_937069	chr20_44502766_-	intronic
ADediting_937070	chr20_44502770_-	intronic
ADediting_937071	chr20_44502796_-	intronic
ADediting_937072	chr20_44502810_-	intronic
ADediting_937073	chr20_44502847_-	intronic
ADediting_937074	chr20_44502856_-	intronic
ADediting_937075	chr20_44502863_-	intronic
ADediting_937076	chr20_44502892_-	intronic
ADediting_937077	chr20_44503404_-	intronic
ADediting_937078	chr20_44503405_-	intronic
ADediting_937079	chr20_44503476_-	intronic
ADediting_937080	chr20_44503526_-	intronic
ADediting_937081	chr20_44503531_-	intronic
ADediting_937082	chr20_44503536_-	intronic
ADediting_937083	chr20_44503539_-	intronic
ADediting_937084	chr20_44503585_-	intronic
ADediting_937085	chr20_44503604_-	intronic
ADediting_937086	chr20_44503610_-	intronic
ADediting_937087	chr20_44505359_-	intronic
ADediting_937088	chr20_44505386_-	intronic
ADediting_937089	chr20_44505398_-	intronic
ADediting_937090	chr20_44505446_-	intronic
ADediting_937091	chr20_44505460_-	intronic
ADediting_937092	chr20_44505489_-	intronic
ADediting_937093	chr20_44505497_-	intronic
ADediting_937094	chr20_44505594_-	intronic
ADediting_937095	chr20_44505678_-	intronic
ADediting_937096	chr20_44505739_-	intronic
ADediting_937097	chr20_44505765_-	intronic
ADediting_937098	chr20_44505773_-	intronic
ADediting_937099	chr20_44505776_-	intronic
ADediting_937100	chr20_44505782_-	intronic
ADediting_937101	chr20_44505788_-	intronic
ADediting_937102	chr20_44505807_-	intronic
ADediting_937103	chr20_44505818_-	intronic
ADediting_937104	chr20_44505827_-	intronic
ADediting_937105	chr20_44505850_-	intronic
ADediting_937106	chr20_44505851_-	intronic
ADediting_937107	chr20_44506056_-	intronic
ADediting_937108	chr20_44506109_-	intronic
ADediting_937109	chr20_44506138_-	intronic
ADediting_937110	chr20_44506144_-	intronic
ADediting_937111	chr20_44506221_-	intronic
ADediting_937112	chr20_44506350_-	intronic
ADediting_937113	chr20_44506414_-	intronic
ADediting_937114	chr20_44506420_-	intronic
ADediting_937115	chr20_44506438_-	intronic
ADediting_937116	chr20_44506464_-	intronic
ADediting_937117	chr20_44506502_-	intronic
ADediting_937118	chr20_44506538_-	intronic
ADediting_937119	chr20_44507614_-	intronic
ADediting_937120	chr20_44507745_-	intronic
ADediting_937121	chr20_44508301_-	intronic
ADediting_937122	chr20_44509559_-	intronic
ADediting_937123	chr20_44509718_-	intronic
ADediting_937124	chr20_44509780_-	intronic
ADediting_937125	chr20_44510579_-	intronic
ADediting_937126	chr20_44510588_-	intronic
ADediting_937127	chr20_44510632_-	intronic
ADediting_937128	chr20_44510646_-	intronic
ADediting_937129	chr20_44510650_-	intronic
ADediting_937130	chr20_44510655_-	intronic
ADediting_937131	chr20_44510668_-	intronic
ADediting_937132	chr20_44510688_-	intronic
ADediting_937133	chr20_44510700_-	intronic
ADediting_937134	chr20_44510703_-	intronic
ADediting_937135	chr20_44510712_-	intronic
ADediting_937136	chr20_44510725_-	intronic
ADediting_937137	chr20_44510728_-	intronic
ADediting_937138	chr20_44510748_-	intronic
ADediting_937139	chr20_44510749_-	intronic
ADediting_937140	chr20_44510759_-	intronic
ADediting_937141	chr20_44510767_-	intronic
ADediting_937142	chr20_44510981_-	intronic
ADediting_937143	chr20_44510982_-	intronic
ADediting_937144	chr20_44510999_-	intronic
ADediting_937145	chr20_44511010_-	intronic
ADediting_937146	chr20_44511021_-	intronic
ADediting_937147	chr20_44511038_-	intronic
ADediting_937148	chr20_44511042_-	intronic
ADediting_937149	chr20_44511074_-	intronic
ADediting_937150	chr20_44511078_-	intronic
ADediting_937151	chr20_44511081_-	intronic
ADediting_937152	chr20_44511082_-	intronic
ADediting_937153	chr20_44511084_-	intronic
ADediting_937154	chr20_44511087_-	intronic
ADediting_937155	chr20_44511096_-	intronic
ADediting_937156	chr20_44511108_-	intronic
ADediting_937157	chr20_44511126_-	intronic
ADediting_937158	chr20_44511141_-	intronic
ADediting_937159	chr20_44511164_-	intronic
ADediting_937160	chr20_44511165_-	intronic
ADediting_937161	chr20_44511186_-	intronic
ADediting_937162	chr20_44511187_-	intronic
ADediting_937163	chr20_44511203_-	intronic
ADediting_937164	chr20_44513361_-	intronic
ADediting_937165	chr20_44513403_-	intronic
ADediting_937166	chr20_44513423_-	intronic
ADediting_937167	chr20_44514570_-	intronic
ADediting_937168	chr20_44514613_-	intronic
ADediting_937169	chr20_44514709_-	intronic
ADediting_937170	chr20_44515137_-	intronic
ADediting_937171	chr20_44515174_-	intronic
ADediting_937172	chr20_44515191_-	intronic
ADediting_937173	chr20_44515226_-	intronic
ADediting_937174	chr20_44515230_-	intronic
ADediting_937175	chr20_44515254_-	intronic
ADediting_937176	chr20_44515267_-	intronic
ADediting_937177	chr20_44515271_-	intronic
ADediting_937178	chr20_44515285_-	intronic
ADediting_937179	chr20_44515291_-	intronic
ADediting_937180	chr20_44515297_-	intronic
ADediting_937181	chr20_44515302_-	intronic
ADediting_937182	chr20_44515340_-	intronic
ADediting_937183	chr20_44515346_-	intronic
ADediting_937184	chr20_44515743_-	intronic
ADediting_937185	chr20_44515759_-	intronic
ADediting_937186	chr20_44515765_-	intronic
ADediting_937187	chr20_44515766_-	intronic
ADediting_937188	chr20_44515767_-	intronic
ADediting_937189	chr20_44515789_-	intronic
ADediting_937190	chr20_44515815_-	intronic
ADediting_937191	chr20_44515849_-	intronic
ADediting_937192	chr20_44515851_-	intronic
ADediting_937193	chr20_44515852_-	intronic
ADediting_937194	chr20_44515859_-	intronic
ADediting_937195	chr20_44515874_-	intronic
ADediting_937196	chr20_44515941_-	intronic
ADediting_937197	chr20_44515944_-	intronic
ADediting_937198	chr20_44516078_-	intronic
ADediting_937199	chr20_44516119_-	intronic
ADediting_937200	chr20_44516122_-	intronic
ADediting_937201	chr20_44516139_-	intronic
ADediting_937202	chr20_44516154_-	intronic
ADediting_937203	chr20_44516180_-	intronic
ADediting_937204	chr20_44516202_-	intronic
ADediting_937205	chr20_44516239_-	intronic
ADediting_937206	chr20_44516245_-	intronic
ADediting_937207	chr20_44516255_-	intronic
ADediting_937208	chr20_44516288_-	intronic
ADediting_937209	chr20_44516428_-	intronic
ADediting_937210	chr20_44516485_-	intronic
ADediting_937211	chr20_44516490_-	intronic
ADediting_937212	chr20_44516505_-	intronic
ADediting_937213	chr20_44516511_-	intronic
ADediting_937214	chr20_44516527_-	intronic
ADediting_937215	chr20_44516528_-	intronic
ADediting_937216	chr20_44516563_-	intronic
ADediting_937217	chr20_44516566_-	intronic
ADediting_937218	chr20_44516608_-	intronic
ADediting_937219	chr20_44516615_-	intronic
ADediting_937220	chr20_44516619_-	intronic
ADediting_937221	chr20_44516634_-	intronic
ADediting_937222	chr20_44516664_-	intronic
ADediting_937223	chr20_44516787_-	intronic
ADediting_937224	chr20_44516792_-	intronic
ADediting_1566920	chr20_44502312_-	intronic
ADediting_1566921	chr20_44502453_-	intronic
ADediting_1566922	chr20_44502465_-	intronic
ADediting_1566923	chr20_44502521_-	intronic
ADediting_1566924	chr20_44502526_-	intronic
ADediting_1566925	chr20_44502695_-	intronic
ADediting_1566926	chr20_44502713_-	intronic
ADediting_1566927	chr20_44502714_-	intronic
ADediting_1566928	chr20_44502751_-	intronic
ADediting_1566929	chr20_44502774_-	intronic
ADediting_1566930	chr20_44502793_-	intronic
ADediting_1566931	chr20_44502800_-	intronic
ADediting_1566932	chr20_44502853_-	intronic
ADediting_1566933	chr20_44503403_-	intronic
ADediting_1566934	chr20_44503413_-	intronic
ADediting_1566935	chr20_44503562_-	intronic
ADediting_1566936	chr20_44507761_-	intronic
ADediting_1566937	chr20_44508401_-	intronic
ADediting_1566938	chr20_44509591_-	intronic
ADediting_1566939	chr20_44509602_-	intronic
ADediting_1566940	chr20_44509644_-	intronic
ADediting_1566941	chr20_44509645_-	intronic
ADediting_1566942	chr20_44509653_-	intronic
ADediting_1566943	chr20_44509657_-	intronic
ADediting_1566944	chr20_44509669_-	intronic
ADediting_1566945	chr20_44509689_-	intronic
ADediting_1566946	chr20_44509712_-	intronic
ADediting_1566947	chr20_44510620_-	intronic
ADediting_1566948	chr20_44510663_-	intronic
ADediting_1566949	chr20_44510664_-	intronic
ADediting_1566950	chr20_44510674_-	intronic
ADediting_1566951	chr20_44510677_-	intronic
ADediting_1566952	chr20_44511035_-	intronic
ADediting_1566953	chr20_44511060_-	intronic
ADediting_1566954	chr20_44511083_-	intronic
ADediting_1566955	chr20_44511089_-	intronic
ADediting_1566956	chr20_44511178_-	intronic
ADediting_1566957	chr20_44513358_-	intronic
ADediting_1640898	chr20_44498324_-	UTR3
ADediting_1640899	chr20_44505778_-	intronic
ADediting_1640900	chr20_44506075_-	intronic
ADediting_1640901	chr20_44508393_-	intronic
ADediting_1640902	chr20_44509729_-	intronic
ADediting_1640903	chr20_44510990_-	intronic
ADediting_1640904	chr20_44511091_-	intronic
ADediting_1640905	chr20_44511118_-	intronic
ADediting_1640906	chr20_44511170_-	intronic

Repat-regional RNA editing(s).

ADeditome ID	Position	Repeat family	Repeat sub family	Repeat name
ADediting_937043	chr20_44496559_-	SINE	Alu	Name=AluSx
ADediting_937044	chr20_44498385_-	SINE	Alu	Name=AluY
ADediting_937045	chr20_44498454_-	SINE	Alu	Name=AluY
ADediting_937046	chr20_44498464_-	SINE	Alu	Name=AluY
ADediting_937047	chr20_44498537_-	SINE	Alu	Name=AluY
ADediting_937048	chr20_44502390_-	SINE	Alu	Name=AluJr
ADediting_937049	chr20_44502413_-	SINE	Alu	Name=AluJr
ADediting_937050	chr20_44502439_-	SINE	Alu	Name=AluJr
ADediting_937051	chr20_44502459_-	SINE	Alu	Name=AluJr
ADediting_937052	chr20_44502461_-	SINE	Alu	Name=AluJr
ADediting_937053	chr20_44502466_-	SINE	Alu	Name=AluJr
ADediting_937054	chr20_44502471_-	SINE	Alu	Name=AluJr
ADediting_937055	chr20_44502514_-	SINE	Alu	Name=AluJr
ADediting_937056	chr20_44502515_-	SINE	Alu	Name=AluJr
ADediting_937057	chr20_44502523_-	SINE	Alu	Name=AluJr
ADediting_937058	chr20_44502545_-	SINE	Alu	Name=AluJr
ADediting_937059	chr20_44502549_-	SINE	Alu	Name=AluJr
ADediting_937060	chr20_44502575_-	SINE	Alu	Name=AluJr
ADediting_937061	chr20_44502578_-	SINE	Alu	Name=AluJr
ADediting_937062	chr20_44502666_-	SINE	Alu	Name=AluJr
ADediting_937063	chr20_44502688_-	SINE	Alu	Name=AluJr
ADediting_937064	chr20_44502696_-	SINE	Alu	Name=AluJr
ADediting_937065	chr20_44502701_-	SINE	Alu	Name=AluJr
ADediting_937066	chr20_44502735_-	SINE	Alu	Name=AluJr
ADediting_937067	chr20_44502739_-	SINE	Alu	Name=AluJr
ADediting_937068	chr20_44502745_-	SINE	Alu	Name=AluJr
ADediting_937069	chr20_44502766_-	SINE	Alu	Name=AluJr
ADediting_937070	chr20_44502770_-	SINE	Alu	Name=AluJr
ADediting_937071	chr20_44502796_-	SINE	Alu	Name=AluJr
ADediting_937072	chr20_44502810_-	SINE	Alu	Name=AluJr
ADediting_937073	chr20_44502847_-	SINE	Alu	Name=AluJr
ADediting_937074	chr20_44502856_-	SINE	Alu	Name=AluJr
ADediting_937075	chr20_44502863_-	SINE	Alu	Name=AluJr
ADediting_937076	chr20_44502892_-	LINE	L1	Name=L1M4
ADediting_937077	chr20_44503404_-	SINE	Alu	Name=AluSx1
ADediting_937078	chr20_44503405_-	SINE	Alu	Name=AluSx1
ADediting_937079	chr20_44503476_-	SINE	Alu	Name=AluSx1
ADediting_937080	chr20_44503526_-	SINE	Alu	Name=AluSx1
ADediting_937081	chr20_44503531_-	SINE	Alu	Name=AluSx1
ADediting_937082	chr20_44503536_-	SINE	Alu	Name=AluSx1
ADediting_937083	chr20_44503539_-	SINE	Alu	Name=AluSx1
ADediting_937084	chr20_44503585_-	SINE	Alu	Name=AluSx1
ADediting_937085	chr20_44503604_-	SINE	Alu	Name=AluSx1
ADediting_937086	chr20_44503610_-	SINE	Alu	Name=AluSx1
ADediting_937087	chr20_44505359_-	SINE	Alu	Name=AluSq2
ADediting_937088	chr20_44505386_-	SINE	Alu	Name=AluSq2
ADediting_937089	chr20_44505398_-	SINE	Alu	Name=AluSq2
ADediting_937090	chr20_44505446_-	SINE	Alu	Name=AluSq2
ADediting_937091	chr20_44505460_-	SINE	Alu	Name=AluSq2
ADediting_937092	chr20_44505489_-	SINE	Alu	Name=AluSq2
ADediting_937093	chr20_44505497_-	SINE	Alu	Name=AluSq2
ADediting_937094	chr20_44505594_-	SINE	Alu	Name=AluSq2
ADediting_937095	chr20_44505678_-	SINE	Alu	Name=AluSq2
ADediting_937096	chr20_44505739_-	SINE	Alu	Name=AluSq2
ADediting_937097	chr20_44505765_-	SINE	Alu	Name=AluSq2
ADediting_937098	chr20_44505773_-	SINE	Alu	Name=AluSq2
ADediting_937099	chr20_44505776_-	SINE	Alu	Name=AluSq2
ADediting_937100	chr20_44505782_-	SINE	Alu	Name=AluSq2
ADediting_937101	chr20_44505788_-	SINE	Alu	Name=AluSq2
ADediting_937102	chr20_44505807_-	SINE	Alu	Name=AluSq2
ADediting_937103	chr20_44505818_-	SINE	Alu	Name=AluSq2
ADediting_937104	chr20_44505827_-	SINE	Alu	Name=AluSq2
ADediting_937105	chr20_44505850_-	SINE	Alu	Name=AluSq2
ADediting_937106	chr20_44505851_-	SINE	Alu	Name=AluSq2
ADediting_937107	chr20_44506056_-	SINE	Alu	Name=AluSq10
ADediting_937108	chr20_44506109_-	SINE	Alu	Name=AluSq10
ADediting_937109	chr20_44506138_-	SINE	Alu	Name=AluSq10
ADediting_937110	chr20_44506144_-	SINE	Alu	Name=AluSq10
ADediting_937111	chr20_44506221_-	SINE	Alu	Name=AluSq10
ADediting_937112	chr20_44506350_-	SINE	Alu	Name=AluSg7
ADediting_937113	chr20_44506414_-	SINE	Alu	Name=AluSg7
ADediting_937114	chr20_44506420_-	SINE	Alu	Name=AluSg7
ADediting_937115	chr20_44506438_-	SINE	Alu	Name=AluSg7
ADediting_937116	chr20_44506464_-	SINE	Alu	Name=AluSg7
ADediting_937117	chr20_44506502_-	SINE	Alu	Name=AluSg7
ADediting_937118	chr20_44506538_-	SINE	Alu	Name=AluSg7
ADediting_937119	chr20_44507614_-	SINE	Alu	Name=AluJb
ADediting_937120	chr20_44507745_-	SINE	Alu	Name=AluJb
ADediting_937121	chr20_44508301_-	SINE	Alu	Name=AluJb
ADediting_937122	chr20_44509559_-	SINE	Alu	Name=AluJo
ADediting_937123	chr20_44509718_-	SINE	Alu	Name=AluJo
ADediting_937124	chr20_44509780_-	SINE	Alu	Name=AluJo
ADediting_937125	chr20_44510579_-	SINE	Alu	Name=AluSg7
ADediting_937126	chr20_44510588_-	SINE	Alu	Name=AluSg7
ADediting_937127	chr20_44510632_-	SINE	Alu	Name=AluSg7
ADediting_937128	chr20_44510646_-	SINE	Alu	Name=AluSg7
ADediting_937129	chr20_44510650_-	SINE	Alu	Name=AluSg7
ADediting_937130	chr20_44510655_-	SINE	Alu	Name=AluSg7
ADediting_937131	chr20_44510668_-	SINE	Alu	Name=AluSg7
ADediting_937132	chr20_44510688_-	SINE	Alu	Name=AluSg7
ADediting_937133	chr20_44510700_-	SINE	Alu	Name=AluSg7
ADediting_937134	chr20_44510703_-	SINE	Alu	Name=AluSg7
ADediting_937135	chr20_44510712_-	SINE	Alu	Name=AluSg7
ADediting_937136	chr20_44510725_-	SINE	Alu	Name=AluSg7
ADediting_937137	chr20_44510728_-	SINE	Alu	Name=AluSg7
ADediting_937138	chr20_44510748_-	SINE	Alu	Name=AluSg7
ADediting_937139	chr20_44510749_-	SINE	Alu	Name=AluSg7
ADediting_937140	chr20_44510759_-	SINE	Alu	Name=AluSg7
ADediting_937141	chr20_44510767_-	SINE	Alu	Name=AluSg7
ADediting_937142	chr20_44510981_-	SINE	Alu	Name=AluSx
ADediting_937143	chr20_44510982_-	SINE	Alu	Name=AluSx
ADediting_937144	chr20_44510999_-	SINE	Alu	Name=AluSx
ADediting_937145	chr20_44511010_-	SINE	Alu	Name=AluSx
ADediting_937146	chr20_44511021_-	SINE	Alu	Name=AluSx
ADediting_937147	chr20_44511038_-	SINE	Alu	Name=AluSx
ADediting_937148	chr20_44511042_-	SINE	Alu	Name=AluSx
ADediting_937149	chr20_44511074_-	SINE	Alu	Name=AluSx
ADediting_937150	chr20_44511078_-	SINE	Alu	Name=AluSx
ADediting_937151	chr20_44511081_-	SINE	Alu	Name=AluSx
ADediting_937152	chr20_44511082_-	SINE	Alu	Name=AluSx
ADediting_937153	chr20_44511084_-	SINE	Alu	Name=AluSx
ADediting_937154	chr20_44511087_-	SINE	Alu	Name=AluSx
ADediting_937155	chr20_44511096_-	SINE	Alu	Name=AluSx
ADediting_937156	chr20_44511108_-	SINE	Alu	Name=AluSx
ADediting_937157	chr20_44511126_-	SINE	Alu	Name=AluSx
ADediting_937158	chr20_44511141_-	SINE	Alu	Name=AluSx
ADediting_937159	chr20_44511164_-	SINE	Alu	Name=AluSx
ADediting_937160	chr20_44511165_-	SINE	Alu	Name=AluSx
ADediting_937161	chr20_44511186_-	SINE	Alu	Name=AluSx
ADediting_937162	chr20_44511187_-	SINE	Alu	Name=AluSx
ADediting_937163	chr20_44511203_-	SINE	Alu	Name=AluSx
ADediting_937164	chr20_44513361_-	SINE	Alu	Name=AluSx3
ADediting_937165	chr20_44513403_-	SINE	Alu	Name=AluSx3
ADediting_937166	chr20_44513423_-	SINE	Alu	Name=AluSx3
ADediting_937167	chr20_44514570_-	SINE	Alu	Name=AluY
ADediting_937168	chr20_44514613_-	SINE	Alu	Name=AluY
ADediting_937169	chr20_44514709_-	SINE	Alu	Name=AluY
ADediting_937170	chr20_44515137_-	SINE	Alu	Name=AluSx
ADediting_937171	chr20_44515174_-	SINE	Alu	Name=AluSx
ADediting_937172	chr20_44515191_-	SINE	Alu	Name=AluSx
ADediting_937173	chr20_44515226_-	SINE	Alu	Name=AluSx
ADediting_937174	chr20_44515230_-	SINE	Alu	Name=AluSx
ADediting_937175	chr20_44515254_-	SINE	Alu	Name=AluSx
ADediting_937176	chr20_44515267_-	SINE	Alu	Name=AluSx
ADediting_937177	chr20_44515271_-	SINE	Alu	Name=AluSx
ADediting_937178	chr20_44515285_-	SINE	Alu	Name=AluSx
ADediting_937179	chr20_44515291_-	SINE	Alu	Name=AluSx
ADediting_937180	chr20_44515297_-	SINE	Alu	Name=AluSx
ADediting_937181	chr20_44515302_-	SINE	Alu	Name=AluSx
ADediting_937182	chr20_44515340_-	SINE	Alu	Name=AluSx
ADediting_937183	chr20_44515346_-	SINE	Alu	Name=AluSx
ADediting_937184	chr20_44515743_-	SINE	Alu	Name=AluSz6
ADediting_937185	chr20_44515759_-	SINE	Alu	Name=AluSz6
ADediting_937186	chr20_44515765_-	SINE	Alu	Name=AluSz6
ADediting_937187	chr20_44515766_-	SINE	Alu	Name=AluSz6
ADediting_937188	chr20_44515767_-	SINE	Alu	Name=AluSz6
ADediting_937189	chr20_44515789_-	SINE	Alu	Name=AluSz6
ADediting_937190	chr20_44515815_-	SINE	Alu	Name=AluSz6
ADediting_937191	chr20_44515849_-	SINE	Alu	Name=AluSz6
ADediting_937192	chr20_44515851_-	SINE	Alu	Name=AluSz6
ADediting_937193	chr20_44515852_-	SINE	Alu	Name=AluSz6
ADediting_937194	chr20_44515859_-	SINE	Alu	Name=AluSz6
ADediting_937195	chr20_44515874_-	SINE	Alu	Name=AluSz6
ADediting_937196	chr20_44515941_-	SINE	Alu	Name=AluSz6
ADediting_937197	chr20_44515944_-	SINE	Alu	Name=AluSz6
ADediting_937198	chr20_44516078_-	SINE	Alu	Name=AluSg4
ADediting_937199	chr20_44516119_-	SINE	Alu	Name=AluSg4
ADediting_937200	chr20_44516122_-	SINE	Alu	Name=AluSg4
ADediting_937201	chr20_44516139_-	SINE	Alu	Name=AluSg4
ADediting_937202	chr20_44516154_-	SINE	Alu	Name=AluSg4
ADediting_937203	chr20_44516180_-	SINE	Alu	Name=AluSg4
ADediting_937204	chr20_44516202_-	SINE	Alu	Name=AluSg4
ADediting_937205	chr20_44516239_-	SINE	Alu	Name=AluSg4
ADediting_937206	chr20_44516245_-	SINE	Alu	Name=AluSg4
ADediting_937207	chr20_44516255_-	SINE	Alu	Name=AluSg4
ADediting_937208	chr20_44516288_-	SINE	Alu	Name=AluSg4
ADediting_937209	chr20_44516428_-	SINE	Alu	Name=AluSz
ADediting_937210	chr20_44516485_-	SINE	Alu	Name=AluSz
ADediting_937211	chr20_44516490_-	SINE	Alu	Name=AluSz
ADediting_937212	chr20_44516505_-	SINE	Alu	Name=AluSz
ADediting_937213	chr20_44516511_-	SINE	Alu	Name=AluSz
ADediting_937214	chr20_44516527_-	SINE	Alu	Name=AluSz
ADediting_937215	chr20_44516528_-	SINE	Alu	Name=AluSz
ADediting_937216	chr20_44516563_-	SINE	Alu	Name=AluSz
ADediting_937217	chr20_44516566_-	SINE	Alu	Name=AluSz
ADediting_937218	chr20_44516608_-	SINE	Alu	Name=AluSz
ADediting_937219	chr20_44516615_-	SINE	Alu	Name=AluSz
ADediting_937220	chr20_44516619_-	SINE	Alu	Name=AluSz
ADediting_937221	chr20_44516634_-	SINE	Alu	Name=AluSz
ADediting_937222	chr20_44516664_-	SINE	Alu	Name=AluSz
ADediting_937223	chr20_44516787_-	SINE	Alu	Name=AluJr
ADediting_937224	chr20_44516792_-	SINE	Alu	Name=AluJr
ADediting_1566920	chr20_44502312_-	SINE	Alu	Name=AluJr
ADediting_1566921	chr20_44502453_-	SINE	Alu	Name=AluJr
ADediting_1566922	chr20_44502465_-	SINE	Alu	Name=AluJr
ADediting_1566923	chr20_44502521_-	SINE	Alu	Name=AluJr
ADediting_1566924	chr20_44502526_-	SINE	Alu	Name=AluJr
ADediting_1566925	chr20_44502695_-	SINE	Alu	Name=AluJr
ADediting_1566926	chr20_44502713_-	SINE	Alu	Name=AluJr
ADediting_1566927	chr20_44502714_-	SINE	Alu	Name=AluJr
ADediting_1566928	chr20_44502751_-	SINE	Alu	Name=AluJr
ADediting_1566929	chr20_44502774_-	SINE	Alu	Name=AluJr
ADediting_1566930	chr20_44502793_-	SINE	Alu	Name=AluJr
ADediting_1566931	chr20_44502800_-	SINE	Alu	Name=AluJr
ADediting_1566932	chr20_44502853_-	SINE	Alu	Name=AluJr
ADediting_1566933	chr20_44503403_-	SINE	Alu	Name=AluSx1
ADediting_1566934	chr20_44503413_-	SINE	Alu	Name=AluSx1
ADediting_1566935	chr20_44503562_-	SINE	Alu	Name=AluSx1
ADediting_1566936	chr20_44507761_-	SINE	Alu	Name=AluJb
ADediting_1566937	chr20_44508401_-	SINE	Alu	Name=AluJb
ADediting_1566938	chr20_44509591_-	SINE	Alu	Name=AluJo
ADediting_1566939	chr20_44509602_-	SINE	Alu	Name=AluJo
ADediting_1566940	chr20_44509644_-	SINE	Alu	Name=AluJo
ADediting_1566941	chr20_44509645_-	SINE	Alu	Name=AluJo
ADediting_1566942	chr20_44509653_-	SINE	Alu	Name=AluJo
ADediting_1566943	chr20_44509657_-	SINE	Alu	Name=AluJo
ADediting_1566944	chr20_44509669_-	SINE	Alu	Name=AluJo
ADediting_1566945	chr20_44509689_-	SINE	Alu	Name=AluJo
ADediting_1566946	chr20_44509712_-	SINE	Alu	Name=AluJo
ADediting_1566947	chr20_44510620_-	SINE	Alu	Name=AluSg7
ADediting_1566948	chr20_44510663_-	SINE	Alu	Name=AluSg7
ADediting_1566949	chr20_44510664_-	SINE	Alu	Name=AluSg7
ADediting_1566950	chr20_44510674_-	SINE	Alu	Name=AluSg7
ADediting_1566951	chr20_44510677_-	SINE	Alu	Name=AluSg7
ADediting_1566952	chr20_44511035_-	SINE	Alu	Name=AluSx
ADediting_1566953	chr20_44511060_-	SINE	Alu	Name=AluSx
ADediting_1566954	chr20_44511083_-	SINE	Alu	Name=AluSx
ADediting_1566955	chr20_44511089_-	SINE	Alu	Name=AluSx
ADediting_1566956	chr20_44511178_-	SINE	Alu	Name=AluSx
ADediting_1566957	chr20_44513358_-	SINE	Alu	Name=AluSx3
ADediting_1640898	chr20_44498324_-	SINE	Alu	Name=AluY
ADediting_1640899	chr20_44505778_-	SINE	Alu	Name=AluSq2
ADediting_1640900	chr20_44506075_-	SINE	Alu	Name=AluSq10
ADediting_1640901	chr20_44508393_-	SINE	Alu	Name=AluJb
ADediting_1640902	chr20_44509729_-	SINE	Alu	Name=AluJo
ADediting_1640903	chr20_44510990_-	SINE	Alu	Name=AluSx
ADediting_1640904	chr20_44511091_-	SINE	Alu	Name=AluSx
ADediting_1640905	chr20_44511118_-	SINE	Alu	Name=AluSx
ADediting_1640906	chr20_44511170_-	SINE	Alu	Name=AluSx

Top

RNA A-to-I editing events in the alternative splicing sites for SERINC3

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	ADeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
A3SS	ADediting_937060	chr20_44502575_-	44502574:44502596	3ss	2e	TTTTTTTTTTTGAAGAGAAGAAG	-7.12	TTTTTTTTTTTGAAGAGAAGAGG	-7.03
A3SS	ADediting_937061	chr20_44502578_-	44502574:44502596	3ss	2i	TTTTTTTTTTTGAAGAGAAGAAG	-7.12	TTTTTTTTTTTGAAGAGAGGAAG	-15.07

Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for SERINC3

Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

- Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

ADeditome ID

Chr

Positoing

Skipped exon

ENSG

ENSTs

Top

Protein coding region RNA A-to-I editings for SERINC3

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

Top

The effects of the RNA editing to the miRNA binding sites for SERINC3

RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_937044

chr20_44498385_-

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-3190-5p

chr20

44498380

44498386

7mer-m8

44498379

44498398

147

-18.34

ADediting_937044

chr20_44498385_-

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-548s

chr20

44498381

44498387

7mer-m8

44498380

44498404

143

-15.64

ADediting_937045

chr20_44498454_-

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-17-3p

chr20

44498451

44498457

7mer-m8

44498450

44498472

150

-21.31

ADediting_937046

chr20_44498464_-

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-4691-3p

chr20

44498460

44498466

7mer-m8

44498459

44498485

152

-29.86

ADediting_937047

chr20_44498537_-

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-324-3p

chr20

44498534

44498540

7mer-m8

44498533

44498555

148

-24.1

ADediting_937047

chr20_44498537_-

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-4793-3p

chr20

44498537

44498543

7mer-m8

44498536

44498558

153

-23.14

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_937044

chr20_44498385_-

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-4794

chr20

44498380

44498386

7mer-m8

44498379

44498401

151

-18.19

ADediting_937044

chr20_44498385_-

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-664a-5p

chr20

44498380

44498386

7mer-m8

44498379

44498402

141

-16.24

ADediting_937045

chr20_44498454_-

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-20b-3p

chr20

44498451

44498457

7mer-m8

44498450

44498472

152

-16.7

ADediting_937046

chr20_44498464_-

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-5690

chr20

44498460

44498466

7mer-m8

44498459

44498479

150

-16.63

ADediting_937047

chr20_44498537_-

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-32-5p

chr20

44498536

44498542

7mer-m8

44498535

44498556

144

-12.53

ADediting_937047

chr20_44498537_-

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-363-3p

chr20

44498536

44498542

7mer-m8

44498535

44498556

147

-16.12

ADediting_937047

chr20_44498537_-

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-92a-3p

chr20

44498536

44498542

7mer-m8

44498535

44498552

155

-26.92

RNA A-to-I editing in lncRNA gained miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_1337757

chr7_5495852_-

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-589-3p

chr20

44498557

44498563

7mer-m8

44498556

44498580

162

-21.11

ADediting_1391023

chr8_140732605_-

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-151a-3p

chr20

44498684

44498690

7mer-m8

44498683

44498703

149

-15.75

ADediting_1631458

chr19_40282624_-

ENSG00000132824.14

ENST00000255175.5

SERINC3-201

hsa-miR-641

chr20

44496333

44496340

8mer-1a

44496333

44496354

147

-13.63

ADediting_1631458

chr19_40282624_-

ENSG00000132824.14

ENST00000411544.5

SERINC3-203

hsa-miR-641

chr20

44496333

44496340

8mer-1a

44496333

44496354

147

-13.63

ADediting_286380

chr11_79422188_-

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-5579-3p

chr20

44498980

44498987

8mer-1a

44498980

44499001

151

-13.45

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_1097295

chr3_85385762_+

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-5688

chr20

44500218

44500224

7mer-m8

44500217

44500234

144

-9.4

ADediting_496066

chr15_66496985_-

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-4512

chr20

44499466

44499472

7mer-m8

44499465

44499486

144

-13.63

ADediting_843620

chr2_207754818_+

ENSG00000132824.14

ENST00000342374.5

SERINC3-202

hsa-miR-4775

chr20

44499364

44499370

7mer-m8

44499363

44499384

147

-3.67

Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for SERINC3

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000342374.5	protein_coding

RNA A-to-I editing in miRNA.

ADeditom_ID

ENST

mir_ID

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

RNA A-to-I editing in mRNA.

ADeditom_ID	ENST	Editing_Information	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
ADediting_1640898	ENST00000342374.5	chr20_44498324_-	3513	-1297.90	-1294.60	-1308.40
ADediting_937044	ENST00000342374.5	chr20_44498385_-	3452	-1294.40	-1294.60	-1308.40
ADediting_937045	ENST00000342374.5	chr20_44498454_-	3383	-1298.20	-1294.60	-1308.40
ADediting_937046	ENST00000342374.5	chr20_44498464_-	3373	-1298.90	-1294.60	-1308.40
ADediting_937047	ENST00000342374.5	chr20_44498537_-	3300	-1300.80	-1294.60	-1308.40

RNA A-to-I editing in lncRNA.

ADeditom_ID

ENST

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

Top

Relation with ADAR for SERINC3

Correlation between ADAR gene expression and RNA editing frequency

Tissue	ADeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
DLPFC	ADediting_937048	chr20_44502390_-	6.46040706423904e-05	0.224914049409394	0.0319895641871133	0.121839816907712	4.89272894512704e-08	0.303710434760469
CER	ADediting_937048	chr20_44502390_-	1.00548348598966e-06	0.386887555289767	0.000141652890784915	0.305780957975478	0.476642001040944	0.0585511175817733
DLPFC	ADediting_937052	chr20_44502461_-	2.12720341640809e-05	0.23890621538061	0.0377041947946511	0.118089438752413	5.2325643463689e-15	0.424721431387174
DLPFC	ADediting_937055	chr20_44502514_-	2.69483651664867e-10	0.348773415328738	5.95629329918779e-06	0.253966620614309	3.71596103089621e-05	0.231987494752239
CER	ADediting_937055	chr20_44502514_-	5.80362228085454e-06	0.360635407573215	0.000555610736941529	0.278615598651061	0.0891970844871249	0.139263624145362
DLPFC	ADediting_937056	chr20_44502515_-	2.66340458989238e-09	0.329827420214318	5.4342324047435e-06	0.255015946456863	4.16154871060602e-06	0.258042640229047
CER	ADediting_937056	chr20_44502515_-	7.22715772957757e-06	0.357181943894324	0.00046792505529798	0.282182343143569	0.0559060357909139	0.156441348683539
TCX	ADediting_937056	chr20_44502515_-	0.000108162072121818	0.310840772210053	0.0130107476199979	0.202365235000933	0.400191130807454	0.0691866365199689
DLPFC	ADediting_937057	chr20_44502523_-	1.16539651147854e-11	0.372852984829165	1.10205161351013e-06	0.272581573424585	2.52634474780435e-07	0.287771359849673
CER	ADediting_937057	chr20_44502523_-	6.84179066165125e-11	0.50064440213432	5.32758604208235e-08	0.426355881592698	9.09222767045707e-05	0.31404998858314
DLPFC	ADediting_937058	chr20_44502545_-	4.98472883827341e-07	0.280875465765693	0.00569263871432047	0.156702006026369	2.62505186569386e-08	0.309513162109337
CER	ADediting_937058	chr20_44502545_-	0.000166193071737637	0.302740274006584	0.00194375994676033	0.251042929144653	0.0592035945336853	0.154413149130782
CER	ADediting_937068	chr20_44502745_-	7.28292809466535e-09	0.450480663657265	5.99665718488668e-05	0.321598053423834	0.239028086782444	0.0967194375836599
CER	ADediting_937070	chr20_44502770_-	2.63105260098417e-05	0.335974654174887	0.000179425403708192	0.301270402520855	0.695357582172223	-0.0322349351386973
CER	ADediting_937071	chr20_44502796_-	0.000185643076970012	0.30061427623975	0.00790883934867255	0.2160956228818	0.84943598354348	-0.0156300232754111
CER	ADediting_937072	chr20_44502810_-	1.65823905753432e-07	0.411697193168303	0.000625351960533538	0.276132206233378	0.942572500649852	0.00593135953722082
DLPFC	ADediting_937074	chr20_44502856_-	2.03144944333858e-05	0.239468310800853	0.0484300223674028	0.112190667889422	5.41386689277361e-19	0.476694509938016
CER	ADediting_937074	chr20_44502856_-	3.87098025795692e-12	0.527900928556174	1.65988110379954e-06	0.379611693971456	0.527356098396666	0.0520065486109421
CER	ADediting_937076	chr20_44502892_-	1.22916517032469e-05	0.348650281576612	0.0103951756411177	0.208656403748107	0.25287094088917	-0.0939377672264626
CER	ADediting_937084	chr20_44503585_-	0.000132914535868018	0.306983581897125	0.00095153131788592	0.26712415671314	0.958300599502008	0.00430515037329283
DLPFC	ADediting_937088	chr20_44505386_-	0.695976027218918	0.0222808240445522	0.101212006683402	-0.0932630534118839	1.3051043754864e-18	0.472077841910333
DLPFC	ADediting_937137	chr20_44510728_-	0.386094056600204	0.0493960227904078	0.106590689757435	-0.0918296995982286	1.24204616039614e-11	0.372384060692691
DLPFC	ADediting_937140	chr20_44510759_-	0.156781499868339	0.0806169541238388	0.212287215651016	-0.0710393747830795	2.02748166691411e-18	0.469740086355447
STG	ADediting_937147	chr20_44511038_-	0.732561032427006	-0.0378384028652091	0.0404949994583538	-0.224034599762147	0.00300884688580875	0.31994731630529
DLPFC	ADediting_937184	chr20_44515743_-	0.0691880908000477	-0.103350402116112	0.00065628541421562	-0.192481923668409	7.28819989205419e-10	0.34070182889262
DLPFC	ADediting_937204	chr20_44516202_-	0.135929253028271	-0.0848800769893989	0.000521407558985263	-0.195933116858371	4.73857715330921e-08	0.304011877760851

Correlation between ADAR gene expression and this gene's expression

Tissue	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
DLPFC	2.73840691669893e-104	0.885032744060807	1.10669206267743e-71	0.80457381503664	0.117827230864508	0.0890100782963212
AC	4.09384121549317e-104	0.921897735710277	2.13495252450595e-63	0.824967481211044	2.38929340457919e-13	0.441467734829154
PCC	9.71197544189433e-60	0.86929191362916	2.61480777125082e-60	0.871224448372808	0.252450112006945	0.0832097420150316
CER	1.01720274007412e-49	0.880041547896197	3.53334060038838e-18	0.633124310789774	0.0233449212813914	0.185105738570693
TCX	6.1478806318447e-54	0.895639865150439	4.69308369381198e-15	0.583437187753974	0.0239361387098196	0.184336477780687
FP	7.31488664809825e-20	0.614492093341852	5.79478904089524e-19	0.602435404514798	0.959642337872839	0.00381970851835981
IFG	5.08917548192906e-05	0.719243296297032	0.0083317432209144	0.515657469214931	0.610549950355273	-0.10704451966654
PG	3.21919329746572e-58	0.869345968795625	1.16125824257515e-26	0.680697955862328	0.822193329220881	-0.0165883187188285
STG	1.1015654878188e-14	0.72055364637698	1.18113682595122e-09	0.604019288914263	0.2007235970746	-0.141018303019991

Top

Relation with AD stages for SERINC3

Correlation between AD stages and RNA editing frequency

Tissue	ADeditomID	position	P-val	Coeff.
IFG	ADediting_937155	chr20_44511096_-	0.0354713369979928	0.422303326441651

Correlation between AD stages and this gene's expression

Tissue

P-val

Coeff.

Top

RelatedDrugs for SERINC3

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

RelatedDiseases for SERINC3

Diseases associated with this gene.
(DisGeNet 4.0)

Gene	Disease ID	Disease name	# pubmeds	Source
SERINC3	C0033578	Prostatic Neoplasms	1	CTD_human
SERINC3	C0376358	Malignant neoplasm of prostate	1	CTD_human

Home

Download

Statistics

Landscape

Help

Contact

Gene summary for SERINC3

RNA A-to-I events for SERINC3

RNA editing positional annotations for SERINC3 using Annovar

RNA A-to-I editing events in the alternative splicing sites for SERINC3

Differntial gene expression between RNA A-to-I edited versus non-edited samples for SERINC3

Protein coding region RNA A-to-I editings for SERINC3

The effects of the RNA editing to the miRNA binding sites for SERINC3

The effects of the RNA editing to the stability of the RNA structures for SERINC3

Relation with ADAR for SERINC3

Relation with AD stages for SERINC3

RelatedDrugs for SERINC3

RelatedDiseases for SERINC3

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited versus non-edited samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with AD stages
	Related drugs with this gene
	Related diseases with this gene