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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for PAPOLA |
 Gene summary |
| Gene information | Gene symbol | PAPOLA | Gene ID | 10914 |
| Gene name | poly(A) polymerase alpha | |
| Synonyms | PAP|PAP-alpha | |
| Cytomap | 14q32.2 | |
| Type of gene | protein-coding | |
| Description | poly(A) polymerase alphapolynucleotide adenylyltransferase alpha | |
| Modification date | 20200313 | |
| UniProtAcc | P51003, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| PAPOLA | GO:0006378 | mRNA polyadenylation | 7590244|19224921 |
| PAPOLA | GO:0031440 | regulation of mRNA 3'-end processing | 19224921 |
Top |
RNA A-to-I events for PAPOLA |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_461368(96504425, +), ADediting_461369(96504447, +), ADediting_461370(96504581, +), ADediting_461371(96504586, +), ADediting_461372(96504626, +), ADediting_461373(96505955, +), ADediting_461374(96506021, +), ADediting_461375(96506043, +), ADediting_461376(96506084, +), ADediting_461377(96506101, +), ADediting_461378(96506166, +), ADediting_461379(96506180, +), ADediting_461380(96518671, +), ADediting_461381(96518801, +), ADediting_461382(96518802, +), ADediting_461383(96518823, +), ADediting_461384(96518825, +), ADediting_461385(96518989, +), ADediting_461386(96519002, +), ADediting_461387(96519014, +), ADediting_461388(96521584, +), ADediting_461389(96521624, +), ADediting_461390(96521707, +), ADediting_461391(96522480, +), ADediting_461392(96522605, +), ADediting_461393(96522619, +), ADediting_461394(96522679, +), ADediting_461395(96523690, +), ADediting_461396(96523691, +), ADediting_461397(96523734, +), ADediting_461398(96523792, +), ADediting_461399(96523809, +), ADediting_461400(96523823, +), ADediting_461401(96523836, +), ADediting_461402(96523849, +), ADediting_461403(96523864, +), ADediting_461404(96523868, +), ADediting_461405(96523875, +), ADediting_461406(96523887, +), ADediting_461407(96524543, +), ADediting_461408(96524547, +), ADediting_461409(96524570, +), ADediting_461410(96524633, +), ADediting_461411(96525604, +), ADediting_461412(96525609, +), ADediting_461413(96525630, +), ADediting_461414(96525631, +), ADediting_461415(96525715, +), ADediting_461416(96526450, +), ADediting_461417(96528650, +), ADediting_461418(96529459, +), ADediting_461419(96529468, +), ADediting_461420(96529476, +), ADediting_461421(96529490, +), ADediting_461422(96529506, +), ADediting_461423(96529519, +), ADediting_461424(96529520, +), ADediting_461425(96529534, +), ADediting_461426(96529535, +), ADediting_461427(96529559, +), ADediting_461428(96529575, +), ADediting_461429(96529601, +), ADediting_461430(96529611, +), ADediting_461431(96529615, +), ADediting_461432(96529628, +), ADediting_461433(96529643, +), ADediting_461434(96529651, +), ADediting_461435(96529663, +), ADediting_461436(96529710, +), ADediting_461437(96530436, +), ADediting_461438(96530499, +), ADediting_461439(96530514, +), ADediting_461440(96530517, +), ADediting_461441(96530527, +), ADediting_461442(96530845, +), ADediting_461443(96530908, +), ADediting_461444(96531128, +), ADediting_461445(96531131, +), ADediting_461446(96531132, +), ADediting_461447(96531141, +), ADediting_461448(96531184, +), ADediting_461449(96531185, +), ADediting_461450(96531187, +), ADediting_461451(96531208, +), ADediting_461452(96531212, +), ADediting_461453(96531263, +), ADediting_461454(96531313, +), ADediting_461455(96533760, +), ADediting_461456(96533815, +), ADediting_461457(96533827, +), ADediting_461458(96549455, +), ADediting_461459(96549946, +), ADediting_461460(96549951, +), ADediting_461461(96549971, +), ADediting_461462(96550025, +), ADediting_461463(96553097, +), ADediting_461464(96553146, +), ADediting_461465(96553164, +), ADediting_461466(96553175, +), ADediting_461467(96553180, +), ADediting_461468(96553185, +), ADediting_461469(96553231, +), ADediting_461470(96553251, +), ADediting_461471(96553257, +), ADediting_461472(96553258, +), ADediting_461473(96553263, +), ADediting_461474(96553264, +), ADediting_461475(96553293, +), ADediting_461476(96553303, +), ADediting_461477(96553312, +), ADediting_461478(96553317, +), ADediting_461479(96553331, +), ADediting_461480(96553390, +), ADediting_461481(96553400, +), ADediting_461482(96553404, +), ADediting_461483(96553413, +), ADediting_461484(96553456, +), ADediting_461485(96553468, +), ADediting_461486(96553476, +), ADediting_461487(96553481, +), ADediting_461488(96553563, +), ADediting_461489(96553566, +), ADediting_461490(96553569, +), ADediting_461491(96553613, +), ADediting_461492(96553630, +), ADediting_461493(96553642, +), ADediting_461494(96553712, +), ADediting_461495(96553721, +), ADediting_461496(96553746, +), ADediting_461497(96564226, +), ADediting_461498(96564306, +), ADediting_1538516(96506104, +), ADediting_1538517(96521616, +), ADediting_1538518(96521699, +), ADediting_1538519(96521747, +), ADediting_1538520(96521843, +), ADediting_1538521(96521860, +), ADediting_1538522(96522484, +), ADediting_1538523(96522485, +), ADediting_1538524(96522510, +), ADediting_1538525(96522515, +), ADediting_1538526(96522523, +), ADediting_1538527(96522565, +), ADediting_1538528(96522602, +), ADediting_1538529(96526472, +), ADediting_1538530(96526610, +), ADediting_1538531(96529672, +), ADediting_1538532(96529692, +), ADediting_1538533(96530422, +), ADediting_1538534(96530854, +), ADediting_1538535(96530914, +), ADediting_1538536(96530915, +), ADediting_1538537(96530916, +), ADediting_1538538(96530971, +), ADediting_1538539(96531262, +), ADediting_1538540(96531321, +), ADediting_1538541(96533684, +), ADediting_1538542(96533694, +), ADediting_1538543(96549522, +), ADediting_1538544(96549897, +), ADediting_1538545(96549952, +), ADediting_1538546(96549967, +), ADediting_1538547(96550027, +), ADediting_1538548(96550104, +), ADediting_1538549(96562160, +), ADediting_1620931(96511379, +), ADediting_1620932(96529671, +), ADediting_1620933(96549974, +), ADediting_1620934(96549975, +), ADediting_1620935(96550094, +), |
Top |
RNA editing positional annotations for PAPOLA using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_461368 | chr14_96504425_+ | intronic |
| ADediting_461369 | chr14_96504447_+ | intronic |
| ADediting_461370 | chr14_96504581_+ | intronic |
| ADediting_461371 | chr14_96504586_+ | intronic |
| ADediting_461372 | chr14_96504626_+ | intronic |
| ADediting_461373 | chr14_96505955_+ | intronic |
| ADediting_461374 | chr14_96506021_+ | intronic |
| ADediting_461375 | chr14_96506043_+ | intronic |
| ADediting_461376 | chr14_96506084_+ | intronic |
| ADediting_461377 | chr14_96506101_+ | intronic |
| ADediting_461378 | chr14_96506166_+ | intronic |
| ADediting_461379 | chr14_96506180_+ | intronic |
| ADediting_461380 | chr14_96518671_+ | intronic |
| ADediting_461381 | chr14_96518801_+ | intronic |
| ADediting_461382 | chr14_96518802_+ | intronic |
| ADediting_461383 | chr14_96518823_+ | intronic |
| ADediting_461384 | chr14_96518825_+ | intronic |
| ADediting_461385 | chr14_96518989_+ | intronic |
| ADediting_461386 | chr14_96519002_+ | intronic |
| ADediting_461387 | chr14_96519014_+ | intronic |
| ADediting_461388 | chr14_96521584_+ | intronic |
| ADediting_461389 | chr14_96521624_+ | intronic |
| ADediting_461390 | chr14_96521707_+ | intronic |
| ADediting_461391 | chr14_96522480_+ | intronic |
| ADediting_461392 | chr14_96522605_+ | intronic |
| ADediting_461393 | chr14_96522619_+ | intronic |
| ADediting_461394 | chr14_96522679_+ | intronic |
| ADediting_461395 | chr14_96523690_+ | intronic |
| ADediting_461396 | chr14_96523691_+ | intronic |
| ADediting_461397 | chr14_96523734_+ | intronic |
| ADediting_461398 | chr14_96523792_+ | intronic |
| ADediting_461399 | chr14_96523809_+ | intronic |
| ADediting_461400 | chr14_96523823_+ | intronic |
| ADediting_461401 | chr14_96523836_+ | intronic |
| ADediting_461402 | chr14_96523849_+ | intronic |
| ADediting_461403 | chr14_96523864_+ | intronic |
| ADediting_461404 | chr14_96523868_+ | intronic |
| ADediting_461405 | chr14_96523875_+ | intronic |
| ADediting_461406 | chr14_96523887_+ | intronic |
| ADediting_461407 | chr14_96524543_+ | intronic |
| ADediting_461408 | chr14_96524547_+ | intronic |
| ADediting_461409 | chr14_96524570_+ | intronic |
| ADediting_461410 | chr14_96524633_+ | intronic |
| ADediting_461411 | chr14_96525604_+ | intronic |
| ADediting_461412 | chr14_96525609_+ | intronic |
| ADediting_461413 | chr14_96525630_+ | intronic |
| ADediting_461414 | chr14_96525631_+ | intronic |
| ADediting_461415 | chr14_96525715_+ | intronic |
| ADediting_461416 | chr14_96526450_+ | intronic |
| ADediting_461417 | chr14_96528650_+ | intronic |
| ADediting_461418 | chr14_96529459_+ | intronic |
| ADediting_461419 | chr14_96529468_+ | intronic |
| ADediting_461420 | chr14_96529476_+ | intronic |
| ADediting_461421 | chr14_96529490_+ | intronic |
| ADediting_461422 | chr14_96529506_+ | intronic |
| ADediting_461423 | chr14_96529519_+ | intronic |
| ADediting_461424 | chr14_96529520_+ | intronic |
| ADediting_461425 | chr14_96529534_+ | intronic |
| ADediting_461426 | chr14_96529535_+ | intronic |
| ADediting_461427 | chr14_96529559_+ | intronic |
| ADediting_461428 | chr14_96529575_+ | intronic |
| ADediting_461429 | chr14_96529601_+ | intronic |
| ADediting_461430 | chr14_96529611_+ | intronic |
| ADediting_461431 | chr14_96529615_+ | intronic |
| ADediting_461432 | chr14_96529628_+ | intronic |
| ADediting_461433 | chr14_96529643_+ | intronic |
| ADediting_461434 | chr14_96529651_+ | intronic |
| ADediting_461435 | chr14_96529663_+ | intronic |
| ADediting_461436 | chr14_96529710_+ | intronic |
| ADediting_461437 | chr14_96530436_+ | intronic |
| ADediting_461438 | chr14_96530499_+ | intronic |
| ADediting_461439 | chr14_96530514_+ | intronic |
| ADediting_461440 | chr14_96530517_+ | intronic |
| ADediting_461441 | chr14_96530527_+ | intronic |
| ADediting_461442 | chr14_96530845_+ | intronic |
| ADediting_461443 | chr14_96530908_+ | intronic |
| ADediting_461444 | chr14_96531128_+ | intronic |
| ADediting_461445 | chr14_96531131_+ | intronic |
| ADediting_461446 | chr14_96531132_+ | intronic |
| ADediting_461447 | chr14_96531141_+ | intronic |
| ADediting_461448 | chr14_96531184_+ | intronic |
| ADediting_461449 | chr14_96531185_+ | intronic |
| ADediting_461450 | chr14_96531187_+ | intronic |
| ADediting_461451 | chr14_96531208_+ | intronic |
| ADediting_461452 | chr14_96531212_+ | intronic |
| ADediting_461453 | chr14_96531263_+ | intronic |
| ADediting_461454 | chr14_96531313_+ | intronic |
| ADediting_461455 | chr14_96533760_+ | UTR3 |
| ADediting_461456 | chr14_96533815_+ | UTR3 |
| ADediting_461457 | chr14_96533827_+ | UTR3 |
| ADediting_461458 | chr14_96549455_+ | intronic |
| ADediting_461459 | chr14_96549946_+ | intronic |
| ADediting_461460 | chr14_96549951_+ | intronic |
| ADediting_461461 | chr14_96549971_+ | intronic |
| ADediting_461462 | chr14_96550025_+ | intronic |
| ADediting_461463 | chr14_96553097_+ | intronic |
| ADediting_461464 | chr14_96553146_+ | intronic |
| ADediting_461465 | chr14_96553164_+ | intronic |
| ADediting_461466 | chr14_96553175_+ | intronic |
| ADediting_461467 | chr14_96553180_+ | intronic |
| ADediting_461468 | chr14_96553185_+ | intronic |
| ADediting_461469 | chr14_96553231_+ | intronic |
| ADediting_461470 | chr14_96553251_+ | intronic |
| ADediting_461471 | chr14_96553257_+ | intronic |
| ADediting_461472 | chr14_96553258_+ | intronic |
| ADediting_461473 | chr14_96553263_+ | intronic |
| ADediting_461474 | chr14_96553264_+ | intronic |
| ADediting_461475 | chr14_96553293_+ | intronic |
| ADediting_461476 | chr14_96553303_+ | intronic |
| ADediting_461477 | chr14_96553312_+ | intronic |
| ADediting_461478 | chr14_96553317_+ | intronic |
| ADediting_461479 | chr14_96553331_+ | intronic |
| ADediting_461480 | chr14_96553390_+ | intronic |
| ADediting_461481 | chr14_96553400_+ | intronic |
| ADediting_461482 | chr14_96553404_+ | intronic |
| ADediting_461483 | chr14_96553413_+ | intronic |
| ADediting_461484 | chr14_96553456_+ | intronic |
| ADediting_461485 | chr14_96553468_+ | intronic |
| ADediting_461486 | chr14_96553476_+ | intronic |
| ADediting_461487 | chr14_96553481_+ | intronic |
| ADediting_461488 | chr14_96553563_+ | intronic |
| ADediting_461489 | chr14_96553566_+ | intronic |
| ADediting_461490 | chr14_96553569_+ | intronic |
| ADediting_461491 | chr14_96553613_+ | intronic |
| ADediting_461492 | chr14_96553630_+ | intronic |
| ADediting_461493 | chr14_96553642_+ | intronic |
| ADediting_461494 | chr14_96553712_+ | intronic |
| ADediting_461495 | chr14_96553721_+ | intronic |
| ADediting_461496 | chr14_96553746_+ | intronic |
| ADediting_461497 | chr14_96564226_+ | intronic |
| ADediting_461498 | chr14_96564306_+ | intronic |
| ADediting_1538516 | chr14_96506104_+ | intronic |
| ADediting_1538517 | chr14_96521616_+ | intronic |
| ADediting_1538518 | chr14_96521699_+ | intronic |
| ADediting_1538519 | chr14_96521747_+ | intronic |
| ADediting_1538520 | chr14_96521843_+ | intronic |
| ADediting_1538521 | chr14_96521860_+ | intronic |
| ADediting_1538522 | chr14_96522484_+ | intronic |
| ADediting_1538523 | chr14_96522485_+ | intronic |
| ADediting_1538524 | chr14_96522510_+ | intronic |
| ADediting_1538525 | chr14_96522515_+ | intronic |
| ADediting_1538526 | chr14_96522523_+ | intronic |
| ADediting_1538527 | chr14_96522565_+ | intronic |
| ADediting_1538528 | chr14_96522602_+ | intronic |
| ADediting_1538529 | chr14_96526472_+ | intronic |
| ADediting_1538530 | chr14_96526610_+ | intronic |
| ADediting_1538531 | chr14_96529672_+ | intronic |
| ADediting_1538532 | chr14_96529692_+ | intronic |
| ADediting_1538533 | chr14_96530422_+ | intronic |
| ADediting_1538534 | chr14_96530854_+ | intronic |
| ADediting_1538535 | chr14_96530914_+ | intronic |
| ADediting_1538536 | chr14_96530915_+ | intronic |
| ADediting_1538537 | chr14_96530916_+ | intronic |
| ADediting_1538538 | chr14_96530971_+ | intronic |
| ADediting_1538539 | chr14_96531262_+ | intronic |
| ADediting_1538540 | chr14_96531321_+ | intronic |
| ADediting_1538541 | chr14_96533684_+ | UTR3 |
| ADediting_1538542 | chr14_96533694_+ | UTR3 |
| ADediting_1538543 | chr14_96549522_+ | intronic |
| ADediting_1538544 | chr14_96549897_+ | intronic |
| ADediting_1538545 | chr14_96549952_+ | intronic |
| ADediting_1538546 | chr14_96549967_+ | intronic |
| ADediting_1538547 | chr14_96550027_+ | intronic |
| ADediting_1538548 | chr14_96550104_+ | intronic |
| ADediting_1538549 | chr14_96562160_+ | intronic |
| ADediting_1620931 | chr14_96511379_+ | intronic |
| ADediting_1620932 | chr14_96529671_+ | intronic |
| ADediting_1620933 | chr14_96549974_+ | intronic |
| ADediting_1620934 | chr14_96549975_+ | intronic |
| ADediting_1620935 | chr14_96550094_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_461368 | chr14_96504425_+ | SINE | Alu | Name=AluJb |
| ADediting_461369 | chr14_96504447_+ | SINE | Alu | Name=AluJb |
| ADediting_461370 | chr14_96504581_+ | SINE | Alu | Name=AluJb |
| ADediting_461371 | chr14_96504586_+ | SINE | Alu | Name=AluJb |
| ADediting_461372 | chr14_96504626_+ | SINE | Alu | Name=AluJb |
| ADediting_461373 | chr14_96505955_+ | SINE | Alu | Name=AluSc |
| ADediting_461374 | chr14_96506021_+ | SINE | Alu | Name=AluSc |
| ADediting_461375 | chr14_96506043_+ | SINE | Alu | Name=AluSc |
| ADediting_461376 | chr14_96506084_+ | SINE | Alu | Name=AluSc |
| ADediting_461377 | chr14_96506101_+ | SINE | Alu | Name=AluSc |
| ADediting_461378 | chr14_96506166_+ | SINE | Alu | Name=AluSc |
| ADediting_461379 | chr14_96506180_+ | SINE | Alu | Name=AluSc |
| ADediting_461380 | chr14_96518671_+ | SINE | Alu | Name=AluYc3 |
| ADediting_461381 | chr14_96518801_+ | SINE | Alu | Name=AluSz |
| ADediting_461382 | chr14_96518802_+ | SINE | Alu | Name=AluSz |
| ADediting_461383 | chr14_96518823_+ | SINE | Alu | Name=AluSz |
| ADediting_461384 | chr14_96518825_+ | SINE | Alu | Name=AluSz |
| ADediting_461385 | chr14_96518989_+ | SINE | Alu | Name=AluSz |
| ADediting_461386 | chr14_96519002_+ | SINE | Alu | Name=AluSz |
| ADediting_461387 | chr14_96519014_+ | SINE | Alu | Name=AluSz |
| ADediting_461388 | chr14_96521584_+ | SINE | Alu | Name=AluJr4 |
| ADediting_461389 | chr14_96521624_+ | SINE | Alu | Name=AluJr4 |
| ADediting_461390 | chr14_96521707_+ | SINE | Alu | Name=AluJr4 |
| ADediting_461391 | chr14_96522480_+ | SINE | Alu | Name=AluJb |
| ADediting_461392 | chr14_96522605_+ | SINE | Alu | Name=AluJb |
| ADediting_461393 | chr14_96522619_+ | SINE | Alu | Name=AluJb |
| ADediting_461394 | chr14_96522679_+ | SINE | Alu | Name=AluJb |
| ADediting_461395 | chr14_96523690_+ | SINE | Alu | Name=AluSg |
| ADediting_461396 | chr14_96523691_+ | SINE | Alu | Name=AluSg |
| ADediting_461397 | chr14_96523734_+ | SINE | Alu | Name=AluSg |
| ADediting_461398 | chr14_96523792_+ | SINE | Alu | Name=AluSg |
| ADediting_461399 | chr14_96523809_+ | SINE | Alu | Name=AluSg |
| ADediting_461400 | chr14_96523823_+ | SINE | Alu | Name=AluSg |
| ADediting_461401 | chr14_96523836_+ | SINE | Alu | Name=AluSg |
| ADediting_461402 | chr14_96523849_+ | SINE | Alu | Name=AluSg |
| ADediting_461403 | chr14_96523864_+ | SINE | Alu | Name=AluSg |
| ADediting_461404 | chr14_96523868_+ | SINE | Alu | Name=AluSg |
| ADediting_461405 | chr14_96523875_+ | SINE | Alu | Name=AluSg |
| ADediting_461406 | chr14_96523887_+ | SINE | Alu | Name=AluSg |
| ADediting_461407 | chr14_96524543_+ | SINE | Alu | Name=AluJb |
| ADediting_461408 | chr14_96524547_+ | SINE | Alu | Name=AluJb |
| ADediting_461409 | chr14_96524570_+ | SINE | Alu | Name=AluJb |
| ADediting_461410 | chr14_96524633_+ | SINE | Alu | Name=AluJb |
| ADediting_461411 | chr14_96525604_+ | SINE | Alu | Name=AluJb |
| ADediting_461412 | chr14_96525609_+ | SINE | Alu | Name=AluJb |
| ADediting_461413 | chr14_96525630_+ | SINE | Alu | Name=AluJb |
| ADediting_461414 | chr14_96525631_+ | SINE | Alu | Name=AluJb |
| ADediting_461415 | chr14_96525715_+ | SINE | Alu | Name=AluJb |
| ADediting_461416 | chr14_96526450_+ | SINE | Alu | Name=AluSz6 |
| ADediting_461417 | chr14_96528650_+ | SINE | Alu | Name=FLAM_A |
| ADediting_461418 | chr14_96529459_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461419 | chr14_96529468_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461420 | chr14_96529476_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461421 | chr14_96529490_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461422 | chr14_96529506_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461423 | chr14_96529519_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461424 | chr14_96529520_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461425 | chr14_96529534_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461426 | chr14_96529535_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461427 | chr14_96529559_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461428 | chr14_96529575_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461429 | chr14_96529601_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461430 | chr14_96529611_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461431 | chr14_96529615_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461432 | chr14_96529628_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461433 | chr14_96529643_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461434 | chr14_96529651_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461435 | chr14_96529663_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461436 | chr14_96529710_+ | SINE | Alu | Name=AluSc8 |
| ADediting_461437 | chr14_96530436_+ | SINE | Alu | Name=AluJr |
| ADediting_461438 | chr14_96530499_+ | SINE | Alu | Name=AluJr |
| ADediting_461439 | chr14_96530514_+ | SINE | Alu | Name=AluJr |
| ADediting_461440 | chr14_96530517_+ | SINE | Alu | Name=AluJr |
| ADediting_461441 | chr14_96530527_+ | SINE | Alu | Name=AluJr |
| ADediting_461442 | chr14_96530845_+ | SINE | Alu | Name=AluJb |
| ADediting_461443 | chr14_96530908_+ | SINE | Alu | Name=AluJb |
| ADediting_461444 | chr14_96531128_+ | SINE | Alu | Name=AluY |
| ADediting_461445 | chr14_96531131_+ | SINE | Alu | Name=AluY |
| ADediting_461446 | chr14_96531132_+ | SINE | Alu | Name=AluY |
| ADediting_461447 | chr14_96531141_+ | SINE | Alu | Name=AluY |
| ADediting_461448 | chr14_96531184_+ | SINE | Alu | Name=AluY |
| ADediting_461449 | chr14_96531185_+ | SINE | Alu | Name=AluY |
| ADediting_461450 | chr14_96531187_+ | SINE | Alu | Name=AluY |
| ADediting_461451 | chr14_96531208_+ | SINE | Alu | Name=AluY |
| ADediting_461452 | chr14_96531212_+ | SINE | Alu | Name=AluY |
| ADediting_461453 | chr14_96531263_+ | SINE | Alu | Name=AluY |
| ADediting_461454 | chr14_96531313_+ | SINE | Alu | Name=AluJb |
| ADediting_461455 | chr14_96533760_+ | SINE | Alu | Name=AluY |
| ADediting_461456 | chr14_96533815_+ | SINE | Alu | Name=AluY |
| ADediting_461457 | chr14_96533827_+ | SINE | Alu | Name=AluY |
| ADediting_461458 | chr14_96549455_+ | SINE | Alu | Name=AluY |
| ADediting_461459 | chr14_96549946_+ | SINE | Alu | Name=AluJr |
| ADediting_461460 | chr14_96549951_+ | SINE | Alu | Name=AluJr |
| ADediting_461461 | chr14_96549971_+ | SINE | Alu | Name=AluJr |
| ADediting_461462 | chr14_96550025_+ | SINE | Alu | Name=AluJr |
| ADediting_461463 | chr14_96553097_+ | SINE | Alu | Name=FLAM_A |
| ADediting_461464 | chr14_96553146_+ | SINE | Alu | Name=FLAM_A |
| ADediting_461465 | chr14_96553164_+ | SINE | Alu | Name=FLAM_A |
| ADediting_461466 | chr14_96553175_+ | SINE | Alu | Name=FLAM_A |
| ADediting_461467 | chr14_96553180_+ | SINE | Alu | Name=FLAM_A |
| ADediting_461468 | chr14_96553185_+ | SINE | Alu | Name=FLAM_A |
| ADediting_461470 | chr14_96553251_+ | SINE | Alu | Name=AluJb |
| ADediting_461471 | chr14_96553257_+ | SINE | Alu | Name=AluJb |
| ADediting_461472 | chr14_96553258_+ | SINE | Alu | Name=AluJb |
| ADediting_461473 | chr14_96553263_+ | SINE | Alu | Name=AluJb |
| ADediting_461474 | chr14_96553264_+ | SINE | Alu | Name=AluJb |
| ADediting_461475 | chr14_96553293_+ | SINE | Alu | Name=AluJb |
| ADediting_461476 | chr14_96553303_+ | SINE | Alu | Name=AluJb |
| ADediting_461477 | chr14_96553312_+ | SINE | Alu | Name=AluJb |
| ADediting_461478 | chr14_96553317_+ | SINE | Alu | Name=AluJb |
| ADediting_461479 | chr14_96553331_+ | SINE | Alu | Name=AluJb |
| ADediting_461480 | chr14_96553390_+ | SINE | Alu | Name=AluJb |
| ADediting_461481 | chr14_96553400_+ | SINE | Alu | Name=AluJb |
| ADediting_461482 | chr14_96553404_+ | SINE | Alu | Name=AluJb |
| ADediting_461483 | chr14_96553413_+ | SINE | Alu | Name=AluJb |
| ADediting_461484 | chr14_96553456_+ | SINE | Alu | Name=AluJb |
| ADediting_461485 | chr14_96553468_+ | SINE | Alu | Name=AluJb |
| ADediting_461486 | chr14_96553476_+ | SINE | Alu | Name=AluJb |
| ADediting_461487 | chr14_96553481_+ | SINE | Alu | Name=AluJb |
| ADediting_461488 | chr14_96553563_+ | SINE | Alu | Name=AluSx1 |
| ADediting_461489 | chr14_96553566_+ | SINE | Alu | Name=AluSx1 |
| ADediting_461490 | chr14_96553569_+ | SINE | Alu | Name=AluSx1 |
| ADediting_461491 | chr14_96553613_+ | SINE | Alu | Name=AluSx1 |
| ADediting_461492 | chr14_96553630_+ | SINE | Alu | Name=AluSx1 |
| ADediting_461493 | chr14_96553642_+ | SINE | Alu | Name=AluSx1 |
| ADediting_461494 | chr14_96553712_+ | SINE | Alu | Name=AluSx1 |
| ADediting_461495 | chr14_96553721_+ | SINE | Alu | Name=AluSx1 |
| ADediting_461496 | chr14_96553746_+ | SINE | Alu | Name=AluSx1 |
| ADediting_461497 | chr14_96564226_+ | LINE | L1 | Name=L1MC5 |
| ADediting_461498 | chr14_96564306_+ | LINE | L1 | Name=L1MC5 |
| ADediting_1538516 | chr14_96506104_+ | SINE | Alu | Name=AluSc |
| ADediting_1538517 | chr14_96521616_+ | SINE | Alu | Name=AluJr4 |
| ADediting_1538518 | chr14_96521699_+ | SINE | Alu | Name=AluJr4 |
| ADediting_1538519 | chr14_96521747_+ | SINE | Alu | Name=AluJr4 |
| ADediting_1538520 | chr14_96521843_+ | SINE | Alu | Name=AluSz |
| ADediting_1538521 | chr14_96521860_+ | SINE | Alu | Name=AluSz |
| ADediting_1538522 | chr14_96522484_+ | SINE | Alu | Name=AluJb |
| ADediting_1538523 | chr14_96522485_+ | SINE | Alu | Name=AluJb |
| ADediting_1538524 | chr14_96522510_+ | SINE | Alu | Name=AluJb |
| ADediting_1538525 | chr14_96522515_+ | SINE | Alu | Name=AluJb |
| ADediting_1538526 | chr14_96522523_+ | SINE | Alu | Name=AluJb |
| ADediting_1538527 | chr14_96522565_+ | SINE | Alu | Name=AluJb |
| ADediting_1538528 | chr14_96522602_+ | SINE | Alu | Name=AluJb |
| ADediting_1538529 | chr14_96526472_+ | SINE | Alu | Name=AluSz6 |
| ADediting_1538530 | chr14_96526610_+ | SINE | Alu | Name=AluSz6 |
| ADediting_1538531 | chr14_96529672_+ | SINE | Alu | Name=AluSc8 |
| ADediting_1538532 | chr14_96529692_+ | SINE | Alu | Name=AluSc8 |
| ADediting_1538533 | chr14_96530422_+ | SINE | Alu | Name=AluJr |
| ADediting_1538534 | chr14_96530854_+ | SINE | Alu | Name=AluJb |
| ADediting_1538535 | chr14_96530914_+ | SINE | Alu | Name=AluJb |
| ADediting_1538536 | chr14_96530915_+ | SINE | Alu | Name=AluJb |
| ADediting_1538537 | chr14_96530916_+ | SINE | Alu | Name=AluJb |
| ADediting_1538538 | chr14_96530971_+ | SINE | Alu | Name=AluJb |
| ADediting_1538539 | chr14_96531262_+ | SINE | Alu | Name=AluY |
| ADediting_1538540 | chr14_96531321_+ | SINE | Alu | Name=AluJb |
| ADediting_1538541 | chr14_96533684_+ | SINE | Alu | Name=AluY |
| ADediting_1538542 | chr14_96533694_+ | SINE | Alu | Name=AluY |
| ADediting_1538543 | chr14_96549522_+ | SINE | Alu | Name=AluY |
| ADediting_1538544 | chr14_96549897_+ | SINE | Alu | Name=AluJr |
| ADediting_1538545 | chr14_96549952_+ | SINE | Alu | Name=AluJr |
| ADediting_1538546 | chr14_96549967_+ | SINE | Alu | Name=AluJr |
| ADediting_1538547 | chr14_96550027_+ | SINE | Alu | Name=AluJr |
| ADediting_1538548 | chr14_96550104_+ | SINE | Alu | Name=AluJr |
| ADediting_1538549 | chr14_96562160_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1620931 | chr14_96511379_+ | SINE | Alu | Name=FLAM_C |
| ADediting_1620932 | chr14_96529671_+ | SINE | Alu | Name=AluSc8 |
| ADediting_1620933 | chr14_96549974_+ | SINE | Alu | Name=AluJr |
| ADediting_1620934 | chr14_96549975_+ | SINE | Alu | Name=AluJr |
| ADediting_1620935 | chr14_96550094_+ | SINE | Alu | Name=AluJr |
Top |
RNA A-to-I editing events in the alternative splicing sites for PAPOLA |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for PAPOLA |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for PAPOLA |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for PAPOLA |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1538541 | chr14_96533684_+ | ENSG00000090060.18 | ENST00000557320.5 | PAPOLA-223 | hsa-miR-4691-3p | chr14 | 96533681 | 96533687 | 7mer-m8 | 96533667 | 96533688 | 150 | -25.69 |
| ADediting_1538542 | chr14_96533694_+ | ENSG00000090060.18 | ENST00000557320.5 | PAPOLA-223 | hsa-miR-4327 | chr14 | 96533692 | 96533698 | 7mer-m8 | 96533681 | 96533699 | 140 | -13.33 |
| ADediting_1538542 | chr14_96533694_+ | ENSG00000090060.18 | ENST00000557320.5 | PAPOLA-223 | hsa-miR-6516-5p | chr14 | 96533690 | 96533696 | 7mer-m8 | 96533675 | 96533697 | 155 | -19.38 |
| ADediting_461455 | chr14_96533760_+ | ENSG00000090060.18 | ENST00000557320.5 | PAPOLA-223 | hsa-miR-3190-5p | chr14 | 96533758 | 96533764 | 7mer-m8 | 96533747 | 96533765 | 148 | -20.6 |
| ADediting_461455 | chr14_96533760_+ | ENSG00000090060.18 | ENST00000557320.5 | PAPOLA-223 | hsa-miR-548s | chr14 | 96533757 | 96533763 | 7mer-m8 | 96533742 | 96533764 | 149 | -16.39 |
| ADediting_461456 | chr14_96533815_+ | ENSG00000090060.18 | ENST00000557320.5 | PAPOLA-223 | hsa-miR-29a-3p | chr14 | 96533813 | 96533819 | 7mer-m8 | 96533799 | 96533820 | 155 | -21.5 |
| ADediting_461456 | chr14_96533815_+ | ENSG00000090060.18 | ENST00000557320.5 | PAPOLA-223 | hsa-miR-29b-3p | chr14 | 96533813 | 96533819 | 7mer-m8 | 96533797 | 96533820 | 150 | -18.73 |
| ADediting_461456 | chr14_96533815_+ | ENSG00000090060.18 | ENST00000557320.5 | PAPOLA-223 | hsa-miR-29c-3p | chr14 | 96533813 | 96533819 | 7mer-m8 | 96533799 | 96533820 | 155 | -21.5 |
| ADediting_461456 | chr14_96533815_+ | ENSG00000090060.18 | ENST00000557320.5 | PAPOLA-223 | hsa-miR-7153-3p | chr14 | 96533810 | 96533816 | 7mer-m8 | 96533800 | 96533817 | 148 | -19.07 |
| ADediting_461456 | chr14_96533815_+ | ENSG00000090060.18 | ENST00000557320.5 | PAPOLA-223 | hsa-miR-767-5p | chr14 | 96533812 | 96533818 | 7mer-m8 | 96533797 | 96533819 | 167 | -25.98 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1538541 | chr14_96533684_+ | ENSG00000090060.18 | ENST00000557320.5 | PAPOLA-223 | hsa-miR-5690 | chr14 | 96533681 | 96533687 | 7mer-m8 | 96533668 | 96533688 | 145 | -17.85 |
| ADediting_461455 | chr14_96533760_+ | ENSG00000090060.18 | ENST00000557320.5 | PAPOLA-223 | hsa-miR-664a-5p | chr14 | 96533758 | 96533764 | 7mer-m8 | 96533743 | 96533765 | 148 | -14.11 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_461368 | chr14_96504425_+ | ENSG00000090060.18 | ENST00000556248.1 | PAPOLA-218 | hsa-miR-10392-3p | chr14 | 96504419 | 96504425 | 7mer-m8 | 96504402 | 96504426 | 153 | -30.88 |
| ADediting_461369 | chr14_96504447_+ | ENSG00000090060.18 | ENST00000556248.1 | PAPOLA-218 | hsa-miR-513a-5p | chr14 | 96504442 | 96504448 | 7mer-m8 | 96504432 | 96504449 | 140 | -14.58 |
| ADediting_461369 | chr14_96504447_+ | ENSG00000090060.18 | ENST00000556248.1 | PAPOLA-218 | hsa-miR-638 | chr14 | 96504447 | 96504453 | 7mer-1a | 96504429 | 96504453 | 155 | -33.61 |
| ADediting_461370 | chr14_96504581_+ | ENSG00000090060.18 | ENST00000556248.1 | PAPOLA-218 | hsa-miR-8052 | chr14 | 96504580 | 96504586 | 7mer-1a | 96504568 | 96504586 | 148 | -29.06 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_461368 | chr14_96504425_+ | ENSG00000090060.18 | ENST00000556248.1 | PAPOLA-218 | hsa-miR-6720-3p | chr14 | 96504424 | 96504430 | 7mer-m8 | 96504410 | 96504431 | 140 | -21.96 |
| ADediting_461369 | chr14_96504447_+ | ENSG00000090060.18 | ENST00000556248.1 | PAPOLA-218 | hsa-miR-10399-5p | chr14 | 96504443 | 96504449 | 7mer-m8 | 96504429 | 96504450 | 144 | -11.5 |
| ADediting_461369 | chr14_96504447_+ | ENSG00000090060.18 | ENST00000556248.1 | PAPOLA-218 | hsa-miR-6504-3p | chr14 | 96504443 | 96504449 | 7mer-m8 | 96504429 | 96504450 | 144 | -12.19 |
| ADediting_461369 | chr14_96504447_+ | ENSG00000090060.18 | ENST00000556248.1 | PAPOLA-218 | hsa-miR-7151-3p | chr14 | 96504441 | 96504448 | 8mer-1a | 96504428 | 96504448 | 150 | -15.55 |
| ADediting_461370 | chr14_96504581_+ | ENSG00000090060.18 | ENST00000556248.1 | PAPOLA-218 | hsa-miR-10399-5p | chr14 | 96504576 | 96504582 | 7mer-m8 | 96504562 | 96504583 | 144 | -10.26 |
| ADediting_461370 | chr14_96504581_+ | ENSG00000090060.18 | ENST00000556248.1 | PAPOLA-218 | hsa-miR-5089-5p | chr14 | 96504580 | 96504586 | 7mer-m8 | 96504568 | 96504587 | 146 | -13.24 |
| ADediting_461371 | chr14_96504586_+ | ENSG00000090060.18 | ENST00000556248.1 | PAPOLA-218 | hsa-miR-5089-5p | chr14 | 96504580 | 96504586 | 7mer-m8 | 96504568 | 96504587 | 146 | -13.24 |
| ADediting_461371 | chr14_96504586_+ | ENSG00000090060.18 | ENST00000556248.1 | PAPOLA-218 | hsa-miR-6506-5p | chr14 | 96504581 | 96504587 | 7mer-m8 | 96504566 | 96504588 | 144 | -16.21 |
| ADediting_461372 | chr14_96504626_+ | ENSG00000090060.18 | ENST00000556248.1 | PAPOLA-218 | hsa-miR-10400-3p | chr14 | 96504620 | 96504626 | 7mer-m8 | 96504606 | 96504627 | 141 | -22.68 |
| ADediting_461372 | chr14_96504626_+ | ENSG00000090060.18 | ENST00000556248.1 | PAPOLA-218 | hsa-miR-1343-3p | chr14 | 96504623 | 96504629 | 7mer-m8 | 96504608 | 96504630 | 150 | -26.73 |
| ADediting_461372 | chr14_96504626_+ | ENSG00000090060.18 | ENST00000556248.1 | PAPOLA-218 | hsa-miR-4674 | chr14 | 96504620 | 96504626 | 7mer-m8 | 96504607 | 96504627 | 147 | -23.74 |
| ADediting_461372 | chr14_96504626_+ | ENSG00000090060.18 | ENST00000556248.1 | PAPOLA-218 | hsa-miR-660-3p | chr14 | 96504625 | 96504631 | 7mer-m8 | 96504612 | 96504632 | 154 | -16.37 |
| ADediting_461372 | chr14_96504626_+ | ENSG00000090060.18 | ENST00000556248.1 | PAPOLA-218 | hsa-miR-6783-3p | chr14 | 96504623 | 96504629 | 7mer-m8 | 96504604 | 96504630 | 152 | -27.23 |
| ADediting_461372 | chr14_96504626_+ | ENSG00000090060.18 | ENST00000556248.1 | PAPOLA-218 | hsa-miR-939-3p | chr14 | 96504622 | 96504629 | 8mer-1a | 96504607 | 96504629 | 146 | -23.71 |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000090060.18 | ENST00000557320.5 | PAPOLA-223 | hsa-miR-381-3p | chr14 | 96532868 | 96532875 | 8mer-1a | 96532856 | 96532875 | 147 | -16.27 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000090060.18 | ENST00000557320.5 | PAPOLA-223 | hsa-miR-381-3p | chr14 | 96534545 | 96534551 | 7mer-m8 | 96534533 | 96534552 | 145 | -12.68 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000090060.18 | ENST00000216277.12 | PAPOLA-201 | hsa-miR-641 | chr14 | 96566988 | 96566994 | 7mer-1a | 96566972 | 96566994 | 142 | -13.83 |
| ADediting_286380 | chr11_79422188_- | ENSG00000090060.18 | ENST00000216277.12 | PAPOLA-201 | hsa-miR-5579-3p | chr14 | 96565944 | 96565950 | 7mer-m8 | 96565929 | 96565951 | 163 | -18.74 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000090060.18 | ENST00000216277.12 | PAPOLA-201 | hsa-miR-4775 | chr14 | 96566248 | 96566254 | 7mer-m8 | 96566230 | 96566255 | 150 | -14.13 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000090060.18 | ENST00000557320.5 | PAPOLA-223 | hsa-miR-4775 | chr14 | 96534614 | 96534620 | 7mer-m8 | 96534596 | 96534621 | 150 | -10.59 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000090060.18 | ENST00000216277.12 | PAPOLA-201 | hsa-miR-381-3p | chr14 | 96565889 | 96565895 | 7mer-m8 | 96565875 | 96565896 | 146 | -10.72 |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000090060.18 | ENST00000216277.12 | PAPOLA-201 | hsa-miR-381-3p | chr14 | 96567032 | 96567038 | 7mer-m8 | 96567015 | 96567039 | 149 | -15.28 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000090060.18 | ENST00000216277.12 | PAPOLA-201 | hsa-miR-381-3p | chr14 | 96565889 | 96565895 | 7mer-m8 | 96565875 | 96565896 | 146 | -10.72 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000090060.18 | ENST00000216277.12 | PAPOLA-201 | hsa-miR-381-3p | chr14 | 96567032 | 96567038 | 7mer-m8 | 96567015 | 96567039 | 149 | -15.28 |
| ADediting_1596844 | chr1_162342605_+ | ENSG00000090060.18 | ENST00000557320.5 | PAPOLA-223 | hsa-miR-556-3p | chr14 | 96534444 | 96534450 | 7mer-m8 | 96534428 | 96534451 | 155 | -12.06 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000090060.18 | ENST00000216277.12 | PAPOLA-201 | hsa-miR-4775 | chr14 | 96565278 | 96565284 | 7mer-m8 | 96565264 | 96565285 | 148 | -2.81 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000090060.18 | ENST00000392990.6 | PAPOLA-202 | hsa-miR-4775 | chr14 | 96565278 | 96565284 | 7mer-m8 | 96565264 | 96565285 | 148 | -2.81 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000090060.18 | ENST00000556459.1 | PAPOLA-220 | hsa-miR-4775 | chr14 | 96565278 | 96565284 | 7mer-m8 | 96565264 | 96565285 | 148 | -2.81 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000090060.18 | ENST00000557320.5 | PAPOLA-223 | hsa-miR-4775 | chr14 | 96533387 | 96533393 | 7mer-m8 | 96533373 | 96533394 | 145 | -5.69 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000090060.18 | ENST00000557320.5 | PAPOLA-223 | hsa-miR-4775 | chr14 | 96534103 | 96534109 | 7mer-m8 | 96534083 | 96534110 | 154 | -15 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for PAPOLA |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000557320.5 | protein_coding |  |  |
| ENST00000556248.1 | lncRNA |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1538541 | ENST00000557320.5 | chr14_96533684_+ | 2063 | -828.10 | -823.70 | -832.90 |
| ADediting_1538542 | ENST00000557320.5 | chr14_96533694_+ | 2073 | -828.40 | -823.70 | -832.90 |
| ADediting_461455 | ENST00000557320.5 | chr14_96533760_+ | 2139 | -825.70 | -823.70 | -832.90 |
| ADediting_461456 | ENST00000557320.5 | chr14_96533815_+ | 2194 | -824.90 | -823.70 | -832.90 |
| ADediting_461457 | ENST00000557320.5 | chr14_96533827_+ | 2206 | -824.60 | -823.70 | -832.90 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_461368 | ENST00000556248.1 | chr14_96504425_+ | 137 | -202.50 | -203.20 | -204.40 |
| ADediting_461369 | ENST00000556248.1 | chr14_96504447_+ | 159 | -205.10 | -203.20 | -204.40 |
| ADediting_461370 | ENST00000556248.1 | chr14_96504581_+ | 293 | -204.60 | -203.20 | -204.40 |
| ADediting_461371 | ENST00000556248.1 | chr14_96504586_+ | 298 | -202.50 | -203.20 | -204.40 |
| ADediting_461372 | ENST00000556248.1 | chr14_96504626_+ | 338 | -202.50 | -203.20 | -204.40 |
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Relation with ADAR for PAPOLA |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_461497 | chr14_96564226_+ | 0.000157298317223432 | 0.303790877779135 | 4.73851826639229e-06 | 0.363792132811826 | 0.0232980825059129 | 0.18516739559423 |
| CER | ADediting_461498 | chr14_96564306_+ | 0.000167260314124194 | 0.302617754837252 | 8.57660662655193e-10 | 0.474479202429024 | 0.00293907380661333 | 0.241250256779825 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 5.59175031294671e-39 | 0.65246161461833 | 4.64193014156057e-26 | 0.55143547735214 | 0.000580352621955193 | 0.194333712727188 |
| AC | 1.25928405027738e-51 | 0.776354930172688 | 1.34924122096957e-33 | 0.667391992540392 | 3.02195516717607e-17 | 0.500379003705839 |
| PCC | 9.88358379231682e-19 | 0.582344287642767 | 7.50066080286689e-20 | 0.597282086901818 | 0.00066209767112686 | 0.244225342059968 |
| CER | 9.78863091456983e-15 | 0.577838429490042 | 1.34657053810142e-21 | 0.678837918376102 | 0.00210002540886353 | 0.249240169642442 |
| TCX | 6.04112445692721e-11 | 0.501876911097652 | 0.0166389762440803 | 0.195264997952417 | 1.02459136289804e-08 | 0.446473531798097 |
| FP | 8.79663849849048e-20 | 0.613438149368924 | 4.71955487463535e-25 | 0.675330301601351 | 0.000149465039617433 | 0.280469124264781 |
| IFG | 3.08651659390678e-06 | 0.786838126845653 | 3.55485308695281e-06 | 0.783911192245507 | 0.00656800802846646 | 0.528842535241792 |
| PG | 5.04797860424803e-40 | 0.784417172063579 | 7.02771525422928e-30 | 0.710389721916878 | 0.985194305526353 | -0.00136991809840582 |
| STG | 1.02536237277701e-10 | 0.633202390335898 | 9.3388332343321e-14 | 0.702683007546375 | 0.141555329486646 | 0.161758137273478 |
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Relation with AD stages for PAPOLA |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_461498 | chr14_96564306_+ | 4.87994182992953e-05 | 0.380426706583458 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 9.64746612979535e-07 | 0.451030917623779 |
| TCX | 3.17338891358583e-08 | 0.505879751984891 |
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RelatedDrugs for PAPOLA |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PAPOLA |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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