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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for TXNL4A |
 Gene summary |
| Gene information | Gene symbol | TXNL4A | Gene ID | 10907 |
| Gene name | thioredoxin like 4A | |
| Synonyms | BMKS|DIB1|DIM1|SNRNP15|TXNL4|U5-15kD | |
| Cytomap | 18q23 | |
| Type of gene | protein-coding | |
| Description | thioredoxin-like protein 4ADIM1 protein homologspliceosomal U5 snRNP-specific 15 kDa proteinthioredoxin-like 4thioredoxin-like U5 snRNP protein U5-15kD | |
| Modification date | 20200313 | |
| UniProtAcc | P83876, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| TXNL4A | GO:0000398 | mRNA splicing, via spliceosome | 28781166 |
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RNA A-to-I events for TXNL4A |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_699097(79971396, -), ADediting_699098(79971400, -), ADediting_699099(79971401, -), ADediting_699100(79971411, -), ADediting_699101(79971419, -), ADediting_699102(79971425, -), ADediting_699103(79972668, -), ADediting_699104(79972736, -), ADediting_699105(79972742, -), ADediting_699106(79972754, -), ADediting_699107(79972758, -), ADediting_699108(79974156, -), ADediting_699109(79974168, -), ADediting_699110(79974178, -), ADediting_699111(79974195, -), ADediting_699112(79974196, -), ADediting_699113(79974540, -), ADediting_699114(79974603, -), ADediting_699115(79974746, -), ADediting_699116(79974751, -), ADediting_699117(79974752, -), ADediting_699118(79974770, -), ADediting_699119(79976990, -), ADediting_699120(79977003, -), ADediting_699121(79977072, -), ADediting_699122(79977907, -), ADediting_699123(79977944, -), ADediting_699124(79981437, -), ADediting_699125(79981454, -), ADediting_699126(79981509, -), ADediting_699127(79981528, -), ADediting_699128(79981564, -), ADediting_699129(79981572, -), ADediting_699130(79983138, -), ADediting_699131(79983139, -), ADediting_699132(79983161, -), ADediting_699133(79983165, -), ADediting_699134(79983170, -), ADediting_699135(79983171, -), ADediting_699136(79983174, -), ADediting_699137(79983176, -), ADediting_699138(79983177, -), ADediting_699139(79983179, -), ADediting_699140(79983194, -), ADediting_699141(79983202, -), ADediting_699142(79983227, -), ADediting_699143(79983233, -), ADediting_699144(79983247, -), ADediting_699145(79983256, -), ADediting_699146(79983273, -), ADediting_699147(79983274, -), ADediting_699148(79983280, -), ADediting_699149(79983281, -), ADediting_699150(79984334, -), ADediting_699151(79984337, -), ADediting_699152(79984359, -), ADediting_699153(79984376, -), ADediting_699154(79984377, -), ADediting_699155(79984390, -), ADediting_699156(79984391, -), ADediting_699157(79984408, -), ADediting_699158(79984410, -), ADediting_699159(79984474, -), ADediting_699160(79984496, -), ADediting_699161(79984501, -), ADediting_699162(79984533, -), ADediting_699163(79984689, -), ADediting_699164(79984746, -), ADediting_699165(79984747, -), ADediting_699166(79984760, -), ADediting_699167(79985381, -), ADediting_699168(79985384, -), ADediting_699169(79985413, -), ADediting_699170(79985428, -), ADediting_699171(79985430, -), ADediting_699172(79985432, -), ADediting_699173(79985454, -), ADediting_699174(79986178, -), ADediting_699175(79986237, -), ADediting_699176(79986321, -), ADediting_699177(80008092, -), ADediting_699178(80008915, -), ADediting_699179(80008916, -), ADediting_699180(80008951, -), ADediting_699181(80019414, -), ADediting_699182(80019417, -), ADediting_699183(80019423, -), ADediting_699184(80019432, -), ADediting_699185(80019442, -), ADediting_699186(80020010, -), ADediting_699187(80020039, -), ADediting_699188(80020062, -), ADediting_699189(80020063, -), ADediting_699190(80020074, -), ADediting_699191(80030801, -), ADediting_699192(80030843, -), ADediting_699193(80030855, -), ADediting_699194(80032647, -), ADediting_1551224(79977901, -), ADediting_1551225(79983098, -), ADediting_1551226(79983183, -), ADediting_1551227(79983189, -), ADediting_1551228(79983204, -), ADediting_1551229(79984427, -), ADediting_1551230(79984445, -), ADediting_1551231(79985303, -), ADediting_1551232(79985446, -), ADediting_1551233(79985468, -), |
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RNA editing positional annotations for TXNL4A using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_699097 | chr18_79971396_- | UTR3 |
| ADediting_699098 | chr18_79971400_- | UTR3 |
| ADediting_699099 | chr18_79971401_- | UTR3 |
| ADediting_699100 | chr18_79971411_- | UTR3 |
| ADediting_699101 | chr18_79971419_- | UTR3 |
| ADediting_699102 | chr18_79971425_- | UTR3 |
| ADediting_699103 | chr18_79972668_- | UTR3 |
| ADediting_699104 | chr18_79972736_- | UTR3 |
| ADediting_699105 | chr18_79972742_- | UTR3 |
| ADediting_699106 | chr18_79972754_- | UTR3 |
| ADediting_699107 | chr18_79972758_- | UTR3 |
| ADediting_699108 | chr18_79974156_- | intronic |
| ADediting_699109 | chr18_79974168_- | intronic |
| ADediting_699110 | chr18_79974178_- | intronic |
| ADediting_699111 | chr18_79974195_- | intronic |
| ADediting_699112 | chr18_79974196_- | intronic |
| ADediting_699113 | chr18_79974540_- | intronic |
| ADediting_699114 | chr18_79974603_- | intronic |
| ADediting_699115 | chr18_79974746_- | intronic |
| ADediting_699116 | chr18_79974751_- | intronic |
| ADediting_699117 | chr18_79974752_- | intronic |
| ADediting_699118 | chr18_79974770_- | intronic |
| ADediting_699119 | chr18_79976990_- | intronic |
| ADediting_699120 | chr18_79977003_- | intronic |
| ADediting_699121 | chr18_79977072_- | intronic |
| ADediting_699122 | chr18_79977907_- | UTR5 |
| ADediting_699123 | chr18_79977944_- | intronic |
| ADediting_699124 | chr18_79981437_- | intronic |
| ADediting_699125 | chr18_79981454_- | intronic |
| ADediting_699126 | chr18_79981509_- | intronic |
| ADediting_699127 | chr18_79981528_- | intronic |
| ADediting_699128 | chr18_79981564_- | intronic |
| ADediting_699129 | chr18_79981572_- | intronic |
| ADediting_699130 | chr18_79983138_- | intronic |
| ADediting_699131 | chr18_79983139_- | intronic |
| ADediting_699132 | chr18_79983161_- | intronic |
| ADediting_699133 | chr18_79983165_- | intronic |
| ADediting_699134 | chr18_79983170_- | intronic |
| ADediting_699135 | chr18_79983171_- | intronic |
| ADediting_699136 | chr18_79983174_- | intronic |
| ADediting_699137 | chr18_79983176_- | intronic |
| ADediting_699138 | chr18_79983177_- | intronic |
| ADediting_699139 | chr18_79983179_- | intronic |
| ADediting_699140 | chr18_79983194_- | intronic |
| ADediting_699141 | chr18_79983202_- | intronic |
| ADediting_699142 | chr18_79983227_- | intronic |
| ADediting_699143 | chr18_79983233_- | intronic |
| ADediting_699144 | chr18_79983247_- | intronic |
| ADediting_699145 | chr18_79983256_- | intronic |
| ADediting_699146 | chr18_79983273_- | intronic |
| ADediting_699147 | chr18_79983274_- | intronic |
| ADediting_699148 | chr18_79983280_- | intronic |
| ADediting_699149 | chr18_79983281_- | intronic |
| ADediting_699150 | chr18_79984334_- | intronic |
| ADediting_699151 | chr18_79984337_- | intronic |
| ADediting_699152 | chr18_79984359_- | intronic |
| ADediting_699153 | chr18_79984376_- | intronic |
| ADediting_699154 | chr18_79984377_- | intronic |
| ADediting_699155 | chr18_79984390_- | intronic |
| ADediting_699156 | chr18_79984391_- | intronic |
| ADediting_699157 | chr18_79984408_- | intronic |
| ADediting_699158 | chr18_79984410_- | intronic |
| ADediting_699159 | chr18_79984474_- | intronic |
| ADediting_699160 | chr18_79984496_- | intronic |
| ADediting_699161 | chr18_79984501_- | intronic |
| ADediting_699162 | chr18_79984533_- | intronic |
| ADediting_699163 | chr18_79984689_- | intronic |
| ADediting_699164 | chr18_79984746_- | intronic |
| ADediting_699165 | chr18_79984747_- | intronic |
| ADediting_699166 | chr18_79984760_- | intronic |
| ADediting_699167 | chr18_79985381_- | intronic |
| ADediting_699168 | chr18_79985384_- | intronic |
| ADediting_699169 | chr18_79985413_- | intronic |
| ADediting_699170 | chr18_79985428_- | intronic |
| ADediting_699171 | chr18_79985430_- | intronic |
| ADediting_699172 | chr18_79985432_- | intronic |
| ADediting_699173 | chr18_79985454_- | intronic |
| ADediting_699174 | chr18_79986178_- | intronic |
| ADediting_699175 | chr18_79986237_- | intronic |
| ADediting_699176 | chr18_79986321_- | intronic |
| ADediting_699177 | chr18_80008092_- | intronic |
| ADediting_699178 | chr18_80008915_- | intronic |
| ADediting_699179 | chr18_80008916_- | intronic |
| ADediting_699180 | chr18_80008951_- | intronic |
| ADediting_699181 | chr18_80019414_- | intronic |
| ADediting_699182 | chr18_80019417_- | intronic |
| ADediting_699183 | chr18_80019423_- | intronic |
| ADediting_699184 | chr18_80019432_- | intronic |
| ADediting_699185 | chr18_80019442_- | intronic |
| ADediting_699186 | chr18_80020010_- | intronic |
| ADediting_699187 | chr18_80020039_- | intronic |
| ADediting_699188 | chr18_80020062_- | intronic |
| ADediting_699189 | chr18_80020063_- | intronic |
| ADediting_699190 | chr18_80020074_- | intronic |
| ADediting_699191 | chr18_80030801_- | intronic |
| ADediting_699192 | chr18_80030843_- | intronic |
| ADediting_699193 | chr18_80030855_- | intronic |
| ADediting_699194 | chr18_80032647_- | intronic |
| ADediting_1551224 | chr18_79977901_- | UTR5 |
| ADediting_1551225 | chr18_79983098_- | intronic |
| ADediting_1551226 | chr18_79983183_- | intronic |
| ADediting_1551227 | chr18_79983189_- | intronic |
| ADediting_1551228 | chr18_79983204_- | intronic |
| ADediting_1551229 | chr18_79984427_- | intronic |
| ADediting_1551230 | chr18_79984445_- | intronic |
| ADediting_1551231 | chr18_79985303_- | intronic |
| ADediting_1551232 | chr18_79985446_- | intronic |
| ADediting_1551233 | chr18_79985468_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_699097 | chr18_79971396_- | SINE | Alu | Name=AluJb |
| ADediting_699098 | chr18_79971400_- | SINE | Alu | Name=AluJb |
| ADediting_699099 | chr18_79971401_- | SINE | Alu | Name=AluJb |
| ADediting_699100 | chr18_79971411_- | SINE | Alu | Name=AluJb |
| ADediting_699101 | chr18_79971419_- | SINE | Alu | Name=AluJb |
| ADediting_699102 | chr18_79971425_- | SINE | Alu | Name=AluJb |
| ADediting_699103 | chr18_79972668_- | SINE | Alu | Name=AluSg |
| ADediting_699104 | chr18_79972736_- | SINE | Alu | Name=AluSg |
| ADediting_699105 | chr18_79972742_- | SINE | Alu | Name=AluSg |
| ADediting_699106 | chr18_79972754_- | SINE | Alu | Name=AluSg |
| ADediting_699107 | chr18_79972758_- | SINE | Alu | Name=AluSg |
| ADediting_699108 | chr18_79974156_- | SINE | Alu | Name=FLAM_C |
| ADediting_699109 | chr18_79974168_- | SINE | Alu | Name=FLAM_C |
| ADediting_699110 | chr18_79974178_- | SINE | Alu | Name=FLAM_C |
| ADediting_699111 | chr18_79974195_- | SINE | Alu | Name=FLAM_C |
| ADediting_699112 | chr18_79974196_- | SINE | Alu | Name=FLAM_C |
| ADediting_699113 | chr18_79974540_- | SINE | Alu | Name=AluYe5 |
| ADediting_699114 | chr18_79974603_- | SINE | Alu | Name=AluJb |
| ADediting_699115 | chr18_79974746_- | SINE | Alu | Name=AluJb |
| ADediting_699116 | chr18_79974751_- | SINE | Alu | Name=AluJb |
| ADediting_699117 | chr18_79974752_- | SINE | Alu | Name=AluJb |
| ADediting_699118 | chr18_79974770_- | SINE | Alu | Name=AluJb |
| ADediting_699119 | chr18_79976990_- | SINE | Alu | Name=AluSq2 |
| ADediting_699120 | chr18_79977003_- | SINE | Alu | Name=AluSq2 |
| ADediting_699121 | chr18_79977072_- | SINE | Alu | Name=AluSq2 |
| ADediting_699122 | chr18_79977907_- | SINE | Alu | Name=AluJb |
| ADediting_699123 | chr18_79977944_- | SINE | Alu | Name=AluJb |
| ADediting_699124 | chr18_79981437_- | SINE | Alu | Name=AluSz |
| ADediting_699125 | chr18_79981454_- | SINE | Alu | Name=AluSz |
| ADediting_699126 | chr18_79981509_- | SINE | Alu | Name=AluSz |
| ADediting_699127 | chr18_79981528_- | SINE | Alu | Name=AluSz |
| ADediting_699128 | chr18_79981564_- | SINE | Alu | Name=AluSz |
| ADediting_699129 | chr18_79981572_- | SINE | Alu | Name=AluSz |
| ADediting_699130 | chr18_79983138_- | SINE | Alu | Name=AluSx1 |
| ADediting_699131 | chr18_79983139_- | SINE | Alu | Name=AluSx1 |
| ADediting_699132 | chr18_79983161_- | SINE | Alu | Name=AluSx1 |
| ADediting_699133 | chr18_79983165_- | SINE | Alu | Name=AluSx1 |
| ADediting_699134 | chr18_79983170_- | SINE | Alu | Name=AluSx1 |
| ADediting_699135 | chr18_79983171_- | SINE | Alu | Name=AluSx1 |
| ADediting_699136 | chr18_79983174_- | SINE | Alu | Name=AluSx1 |
| ADediting_699137 | chr18_79983176_- | SINE | Alu | Name=AluSx1 |
| ADediting_699138 | chr18_79983177_- | SINE | Alu | Name=AluSx1 |
| ADediting_699139 | chr18_79983179_- | SINE | Alu | Name=AluSx1 |
| ADediting_699140 | chr18_79983194_- | SINE | Alu | Name=AluSx1 |
| ADediting_699141 | chr18_79983202_- | SINE | Alu | Name=AluSx1 |
| ADediting_699142 | chr18_79983227_- | SINE | Alu | Name=AluSx1 |
| ADediting_699143 | chr18_79983233_- | SINE | Alu | Name=AluSx1 |
| ADediting_699144 | chr18_79983247_- | SINE | Alu | Name=AluSx1 |
| ADediting_699145 | chr18_79983256_- | SINE | Alu | Name=AluSx1 |
| ADediting_699146 | chr18_79983273_- | SINE | Alu | Name=AluSx1 |
| ADediting_699147 | chr18_79983274_- | SINE | Alu | Name=AluSx1 |
| ADediting_699148 | chr18_79983280_- | SINE | Alu | Name=AluSx1 |
| ADediting_699149 | chr18_79983281_- | SINE | Alu | Name=AluSx1 |
| ADediting_699150 | chr18_79984334_- | SINE | Alu | Name=AluSz6 |
| ADediting_699151 | chr18_79984337_- | SINE | Alu | Name=AluSz6 |
| ADediting_699152 | chr18_79984359_- | SINE | Alu | Name=AluSz6 |
| ADediting_699153 | chr18_79984376_- | SINE | Alu | Name=AluSz6 |
| ADediting_699154 | chr18_79984377_- | SINE | Alu | Name=AluSz6 |
| ADediting_699155 | chr18_79984390_- | SINE | Alu | Name=AluSz6 |
| ADediting_699156 | chr18_79984391_- | SINE | Alu | Name=AluSz6 |
| ADediting_699157 | chr18_79984408_- | SINE | Alu | Name=AluSz6 |
| ADediting_699158 | chr18_79984410_- | SINE | Alu | Name=AluSz6 |
| ADediting_699159 | chr18_79984474_- | SINE | Alu | Name=AluSz6 |
| ADediting_699160 | chr18_79984496_- | SINE | Alu | Name=AluSz6 |
| ADediting_699161 | chr18_79984501_- | SINE | Alu | Name=AluSz6 |
| ADediting_699162 | chr18_79984533_- | SINE | Alu | Name=AluSz6 |
| ADediting_699163 | chr18_79984689_- | SINE | Alu | Name=AluJo |
| ADediting_699164 | chr18_79984746_- | SINE | Alu | Name=AluJo |
| ADediting_699165 | chr18_79984747_- | SINE | Alu | Name=AluJo |
| ADediting_699166 | chr18_79984760_- | SINE | Alu | Name=AluJo |
| ADediting_699167 | chr18_79985381_- | SINE | Alu | Name=AluJb |
| ADediting_699168 | chr18_79985384_- | SINE | Alu | Name=AluJb |
| ADediting_699169 | chr18_79985413_- | SINE | Alu | Name=AluJb |
| ADediting_699170 | chr18_79985428_- | SINE | Alu | Name=AluJb |
| ADediting_699171 | chr18_79985430_- | SINE | Alu | Name=AluJb |
| ADediting_699172 | chr18_79985432_- | SINE | Alu | Name=AluJb |
| ADediting_699173 | chr18_79985454_- | SINE | Alu | Name=AluJb |
| ADediting_699174 | chr18_79986178_- | SINE | Alu | Name=AluJb |
| ADediting_699175 | chr18_79986237_- | SINE | Alu | Name=AluJb |
| ADediting_699176 | chr18_79986321_- | SINE | Alu | Name=AluJb |
| ADediting_699177 | chr18_80008092_- | SINE | Alu | Name=AluJb |
| ADediting_699178 | chr18_80008915_- | SINE | Alu | Name=AluSx4 |
| ADediting_699179 | chr18_80008916_- | SINE | Alu | Name=AluSx4 |
| ADediting_699180 | chr18_80008951_- | SINE | Alu | Name=AluSx4 |
| ADediting_699181 | chr18_80019414_- | LTR | ERVL-MaLR | Name=THE1A |
| ADediting_699182 | chr18_80019417_- | LTR | ERVL-MaLR | Name=THE1A |
| ADediting_699183 | chr18_80019423_- | LTR | ERVL-MaLR | Name=THE1A |
| ADediting_699184 | chr18_80019432_- | LTR | ERVL-MaLR | Name=THE1A |
| ADediting_699185 | chr18_80019442_- | LTR | ERVL-MaLR | Name=THE1A |
| ADediting_699186 | chr18_80020010_- | LTR | ERVL-MaLR | Name=THE1B |
| ADediting_699187 | chr18_80020039_- | LTR | ERVL-MaLR | Name=THE1B |
| ADediting_699188 | chr18_80020062_- | LTR | ERVL-MaLR | Name=THE1B |
| ADediting_699189 | chr18_80020063_- | LTR | ERVL-MaLR | Name=THE1B |
| ADediting_699190 | chr18_80020074_- | LTR | ERVL-MaLR | Name=THE1B |
| ADediting_699191 | chr18_80030801_- | SINE | Alu | Name=AluSz |
| ADediting_699192 | chr18_80030843_- | SINE | Alu | Name=AluSz |
| ADediting_699193 | chr18_80030855_- | SINE | Alu | Name=AluSz |
| ADediting_699194 | chr18_80032647_- | SINE | Alu | Name=AluSz |
| ADediting_1551224 | chr18_79977901_- | SINE | Alu | Name=AluJb |
| ADediting_1551225 | chr18_79983098_- | SINE | Alu | Name=AluSx1 |
| ADediting_1551226 | chr18_79983183_- | SINE | Alu | Name=AluSx1 |
| ADediting_1551227 | chr18_79983189_- | SINE | Alu | Name=AluSx1 |
| ADediting_1551228 | chr18_79983204_- | SINE | Alu | Name=AluSx1 |
| ADediting_1551229 | chr18_79984427_- | SINE | Alu | Name=AluSz6 |
| ADediting_1551230 | chr18_79984445_- | SINE | Alu | Name=AluSz6 |
| ADediting_1551231 | chr18_79985303_- | SINE | Alu | Name=AluJb |
| ADediting_1551232 | chr18_79985446_- | SINE | Alu | Name=AluJb |
| ADediting_1551233 | chr18_79985468_- | SINE | Alu | Name=AluJb |
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RNA A-to-I editing events in the alternative splicing sites for TXNL4A |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for TXNL4A |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |